Click here to access PB0242 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0242 P02766 Transthyretin TTR ATTR, CTS, CTS1, HEL111, HsT2651, PALB, TBPA, TTN Homo_sapiens Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain.

DomainsGene Ontology
PF00576 (Transthyretin)
GO:0005179 (enables) hormone activity
GO:0005515 (enables) protein binding
GO:0042562 (enables) hormone binding
GO:0042802 (enables) identical protein binding
GO:0044877 (enables) protein-containing complex binding
GO:0070324 (enables) thyroid hormone binding
GO:0006144 (involved in) purine nucleobase metabolic process
GO:0007165 (involved in) signal transduction
GO:0042572 (involved in) retinol metabolic process
GO:0070327 (involved in) thyroid hormone transport
GO:0005576 (located in) extracellular region
GO:0005615 (located in) extracellular space
GO:0005737 (located in) cytoplasm
GO:0035578 (located in) azurophil granule lumen
GO:0070062 (located in) extracellular exosome
GO:0032991 (part of) protein-containing complex

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)