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| PBID | Uniprot | Name | Gene | Alternative | Organism | Uniprot Description |
| PB0234 | P08648 | Integrin alpha-5 | ITGA5 | CD49e, FNRA, VLA-5, VLA5A, integrin subunit alpha 5 | Homo_sapiens | (Microbial infection) In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. |
| Domains | Gene Ontology |
| PF01839 (2_FG-GAP) PF08441 (Integrin_alpha2) |
GO:0005911 (colocalizes with) cell-cell junction
GO:0032587 (colocalizes with) ruffle membrane GO:0001618 (enables) virus receptor activity GO:0005154 (enables) epidermal growth factor receptor binding GO:0005161 (enables) platelet-derived growth factor receptor binding GO:0005178 (enables) integrin binding GO:0005515 (enables) protein binding GO:0043184 (enables) vascular endothelial growth factor receptor 2 binding GO:0046872 (enables) metal ion binding GO:0050839 (enables) cell adhesion molecule binding GO:0001525 (involved in) angiogenesis GO:0007044 (involved in) cell-substrate junction assembly GO:0007155 (involved in) cell adhesion GO:0007157 (involved in) heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007159 (involved in) leukocyte cell-cell adhesion GO:0007160 (involved in) cell-matrix adhesion GO:0007229 (involved in) integrin-mediated signaling pathway GO:0007565 (involved in) female pregnancy GO:0007613 (involved in) memory GO:0010811 (involved in) positive regulation of cell-substrate adhesion GO:0023035 (involved in) CD40 signaling pathway GO:0030335 (involved in) positive regulation of cell migration GO:0030949 (involved in) positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0031589 (involved in) cell-substrate adhesion GO:0033627 (involved in) cell adhesion mediated by integrin GO:0033631 (involved in) cell-cell adhesion mediated by integrin GO:0034113 (involved in) heterotypic cell-cell adhesion GO:0035313 (involved in) wound healing, spreading of epidermal cells GO:0035987 (involved in) endodermal cell differentiation GO:0045765 (involved in) regulation of angiogenesis GO:0046718 (involved in) viral entry into host cell GO:0050731 (involved in) positive regulation of peptidyl-tyrosine phosphorylation GO:0098609 (involved in) cell-cell adhesion GO:1903672 (involved in) positive regulation of sprouting angiogenesis GO:2000811 (involved in) negative regulation of anoikis GO:0001726 (located in) ruffle GO:0005737 (located in) cytoplasm GO:0005783 (located in) endoplasmic reticulum GO:0005794 (located in) Golgi apparatus GO:0005886 (located in) plasma membrane GO:0005925 (located in) focal adhesion GO:0009897 (located in) external side of plasma membrane GO:0009986 (located in) cell surface GO:0016020 (located in) membrane GO:0016021 (located in) integral component of membrane GO:0031410 (located in) cytoplasmic vesicle GO:0045202 (located in) synapse GO:0070161 (located in) anchoring junction GO:0008305 (part of) integrin complex GO:0034674 (part of) integrin alpha5-beta1 complex GO:0071062 (part of) alphav-beta3 integrin-vitronectin complex |
| External Links | Description |
| Intact | Open source database system and analysis tools for molecular interaction data. |
| Protein Atlas | An open access resource for human proteins |
| InterPro (new pfam) | InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. |