PB0232

DATABASE

Click here to access PB0232 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0232	P02671	Fibrinogen alpha chain	FGA	Fib2	Homo_sapiens	Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.

Domains

Gene Ontology

PF00147 (Fibrinogen_C) PF08702 (Fib_alpha) PF12160 (Fibrinogen_aC)

GO:0005102 (contributes to) signaling receptor binding GO:0050839 (contributes to) cell adhesion molecule binding GO:0005198 (enables) structural molecule activity GO:0005201 (enables) extracellular matrix structural constituent GO:0005515 (enables) protein binding GO:0046872 (enables) metal ion binding GO:0002250 (involved in) adaptive immune response GO:0002376 (involved in) immune system process GO:0007160 (involved in) cell-matrix adhesion GO:0007596 (involved in) blood coagulation GO:0007599 (involved in) hemostasis GO:0030168 (involved in) platelet activation GO:0031639 (involved in) plasminogen activation GO:0034116 (involved in) positive regulation of heterotypic cell-cell adhesion GO:0042730 (involved in) fibrinolysis GO:0043152 (involved in) induction of bacterial agglutination GO:0045087 (involved in) innate immune response GO:0045907 (involved in) positive regulation of vasoconstriction GO:0045921 (involved in) positive regulation of exocytosis GO:0050714 (involved in) positive regulation of protein secretion GO:0051258 (involved in) protein polymerization GO:0051592 (involved in) response to calcium ion GO:0065003 (involved in) protein-containing complex assembly GO:0070374 (involved in) positive regulation of ERK1 and ERK2 cascade GO:0070527 (involved in) platelet aggregation GO:0072377 (involved in) blood coagulation, common pathway GO:0072378 (involved in) blood coagulation, fibrin clot formation GO:0090277 (involved in) positive regulation of peptide hormone secretion GO:1900026 (involved in) positive regulation of substrate adhesion-dependent cell spreading GO:1902042 (involved in) negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:2000352 (involved in) negative regulation of endothelial cell apoptotic process GO:0005576 (located in) extracellular region GO:0005615 (located in) extracellular space GO:0005783 (located in) endoplasmic reticulum GO:0005788 (located in) endoplasmic reticulum lumen GO:0005886 (located in) plasma membrane GO:0009897 (located in) external side of plasma membrane GO:0009986 (located in) cell surface GO:0031091 (located in) platelet alpha granule GO:0031093 (located in) platelet alpha granule lumen GO:0062023 (located in) collagen-containing extracellular matrix GO:0070062 (located in) extracellular exosome GO:0072562 (located in) blood microparticle GO:0110165 (located in) cellular anatomical entity GO:1903561 (located in) extracellular vesicle GO:0005577 (part of) fibrinogen complex

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|P02671|FIBA_HUMAN Fibrinogen alpha chain OS=Homo sapiens OX=9606 GN=FGA PE=1 SV=2 MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDW NYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSA NNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSC RGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQ LQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSS GPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTW NPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNV SPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTK EVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEF VSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKS YKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIFS VYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQR GSVLRVELEDWAGNEAYAEYHFRVGSEAEGYALQVSSYEGTAGDALIEGSVEEGAEYTSH NNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENG VVWVSFRGADYSLRAVRMKIRPLVTQ >sp|P02671-2|FIBA_HUMAN Isoform 2 of Fibrinogen alpha chain OS=Homo sapiens OX=9606 GN=FGA MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDW NYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSA NNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSC RGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQ LQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSS GPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTW NPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNV SPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTK EVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEF VSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKS YKMADEAGSEADHEGTHSTKRGHAKSRPVRGIHTSPLGKPSLSP
Selected proteins from model organisms >sp|P02671|FIBA_HUMAN Fibrinogen alpha chain OS=Homo sapiens OX=9606 GN=FGA PE=1 SV=2 MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDW NYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSA NNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSC RGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQ LQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSS GPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTW NPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNV SPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTK EVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEF VSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKS YKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIFS VYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQR GSVLRVELEDWAGNEAYAEYHFRVGSEAEGYALQVSSYEGTAGDALIEGSVEEGAEYTSH NNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENG VVWVSFRGADYSLRAVRMKIRPLVTQ >sp|P02671-2|FIBA_HUMAN Isoform 2 of Fibrinogen alpha chain OS=Homo sapiens OX=9606 GN=FGA MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDW NYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSA NNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSC RGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQ LQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSS GPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTW NPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNV SPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTK EVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEF VSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKS YKMADEAGSEADHEGTHSTKRGHAKSRPVRGIHTSPLGKPSLSP >NP_001104518.1 fibrinogen alpha chain isoform 1 preproprotein [Mus musculus] MLSLRVTCLILSVASTVWTTDTEDKGEFLSEGGGVRGPRVVERHQSQCKDSDWPFCSDDDWNHKCPSGCR MKGLIDEANQDFTNRINKLKNSLFDFQRNNKDSNSLTRNIMEYLRGDFANANNFDNTYGQVSEDLRRRIE ILRRKVIEKAQQIQALQSNVRAQLIDMKRLEVDIDIKIRSCKGSCSRAVNREINLQDYEGHQKQLQQVIA KELLPTKDRQYLPALKMSPVPDLVPGSFKSQLQEAPPEWKALTEMRQMRMELERPGKDGGSRGDSPGDSR GDSRGDFATRGPGSKAENPTNPGPGGSGYWRPGNSGSGSDGNRNPGTTGSDGTGDWGTGSPRPGSDSGNF RPANPNWGVFSEFGDSSSPATRKEYHTGKAVTSKGDKELLIGKEKVTSSGTSTTHRSCSKTITKTVTGPD GRREVVKEVITSDDGSDCGDATELDISHSFSGSLDELSERHPDLSGFFDNHFGLISPNFKEFGSKTHSDS DILTNIEDPSSHVPEFSSSSKTSTVKKQVTKTYKMADEAGSEAHREGETRNTKRGRARARPTRDCDDVLQ TQTSGAQNGIFSIKPPGSSKVFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEF WLGNDYLHLLTLRGSVLRVELEDWAGKEAYAEYHFRVGSEAEGYALQVSSYRGTAGDALVQGSVEEGTEY TSHSNMQFSTFDRDADQWEENCAEVYGGGWWYNSCQAANLNGIYYPGGTYDPRNNSPYEIENGVVWVPFR GADYSLRAVRMKIRPLVGQ >NP_001008724.1 fibrinogen alpha chain isoform 1 precursor [Rattus norvegicus] MLSLRVACLILSLASTVWTADTGTTSEFIEAGGDIRGPRIVERQPSQCKETDWPFCSDEDWNHKCPSGCR MKGLIDEANQDFTNRINKLKNSLFDFQKNNKDSNSLTRNIMEYLRGDFANANNFDNTFGQVSEDLRRRIE ILKRKVIEKAQQIQVLQKDVRDQLIDMKRLEVDIDIKIRSCKGSCSRSVSREINLKDYEGQQKQLEQVIA KELLPAKDRQYLPAIKMSPVPDLVPGSFKSQLQEGPPEWKALTEMRQMRMELERPGKDGASRGDLPGDSR GDSATRGPGSKIENPMTPGHGGSGYWRPGSSGSGSDGNWGSGTTGSDDTGTWGAGSSRPSSGSGNLKPSN PDWGEFSEFGGSSSPATRKEYHTGKLVTSKGDKELLIGNEKVTSTGTSTTRRSCSKTITKTVLGNDGHRE VVKEVVTSDDGSDCGDGMDLGLTHSFSGRLDELSRMHPELGSFYDSRFGSLTSNFKEFGSKTSDSDIFTD IENPSSHVPEFSSSSKTSTVRKQVTKSYKMADEAASEAHQEGDTRTTKRGRARTMRDCDDVLQTHPSGAQ NGIFSIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNDYL HLLTLRGSVLRVELEDWAGKEAYAEYHFRVGSEAEGYALQVSSYQGTAGDALMEGSVEEGTEYTSHSNMQ FSTFDRDADQWEENCAEVYGGGWWYNSCQAANLNGIYYPGGTYDPRNNSPYEIENGVVWVPFRGADYSLR AVRMKIRPLVGQ >NP_001258840.1 fibrinogen alpha chain isoform 1 precursor [Gallus gallus] MIPVTILCVLLCLNLAWAQDGKTTFEKEGGGGRGPRILENMHESSCKYEKNWPICVDDDWGTKCPSGCRM QGIIDDTDQNYSQRIDNIRQQLADSQNKYKTSNRVIVETINILKPGLEGAQQLDENYGHVSTELRRRIVT LKQRVATQVNRIKALQNSIQEQVVEMKRLEVDIDIKIRACKGSCARSFDYQVDKEGYDNIQKHLTQASSI DMHPDFQTTTLSTLKMRPLKDSNVPEHFKLKPSPEMQAMSAFNNIKQMQVVLERPETDHVAEARGDSSPS HTGKLITSSHRRESPSLVDKTSSASSVHRCTRTVTKKVISGPDGPREEIVEKMVSSDGSDCSHLQGGREG STYHFSGTGDFHKLDRLLPDLESFFTHDSVSTSSRHSIGSSTSSHVTGAGSSHLGTGGKDKFTDLGEEEE DDFGGLQPSGFAAGSASHSKTVLTSSSSSFNKGGSTFETKSLKTRETSEQLGGVQHDQSAEDTPDFKARS FRPAAMSTRRSYNGKDCDDIRQKHTSGAKSGIFKIKPEGSNKVLSVYCDQETTLGGWLLIQQRMDGSVNF NRTWQDYRRGFGSVDGKGQGELWLGNENIHLLTQNDTLLRVELEDWDGNAAYAEYIVQVGTEAEGYALTV SSYEGTAGDALVAGWLEEGSEYTSHAQMQFSTFDRDQDHWEESCAEVYGGGWWYNSCQAANLNGIYYPGG HYDPRYNVPYEIENGVVWIPFRASDYSLKVVRMKIRPLETL >XP_001136067.1 fibrinogen alpha chain [Pan troglodytes] MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDWNYKCPSGCRM KGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSANNRDNTYNRVSEDLRSRIEV LKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCSRALAREVDLKDYEDQQKQLEQVIAK DLLPSRDRQHLPLIKMKPVPDLVPGNFKSQLQKAPPEWKALTDMPQMRMELERPGRNEITRGDSTSYGTG SETESPRNPSSAGSWNPGSSGPGSSGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPG SPRPGSTGTWNPGSSEHGSAGHWTSESSVSGSTGQWHSESGSFRPDSSGSGNARPTNPDWGTFEEVSGNV SPGTRREYHTEKLVTSKGDKELTTGKEKVTSGSTTTTRRSCSKTVTKTFIGHDGHKEVTKEVVTSEDGSD CPEAIDLGTLSGIGTLDEFRHRHPDEATFFDTASTGKTFSGLFSPMFREFVSETESRGSESGIFTNTKES SSHPPGIAEFPSRGKTSSHSKQFTSGTSYSRGGSTFESKSYKMADEAGSEADHEGTHSTKRGHAKSRPVR DCDDVLQTHPSGTQSGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLN DEGEGEFWLGNDYLHLLTQRGSVLRVELEDWAGNEAYAEYHFWVGSEAEGYALQVSSYEGTAGDALIEGS VEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENG VVWVSFRGADYSLRAVRMKIRPLVTQ >XP_038544611.1 fibrinogen alpha chain isoform X1 [Canis lupus familiaris] MFSAKILCLVLSVVGTVWTTNSKEGEFIAEGGGVRGPRIVERQQSACKETDWPFCSDEDWNYKCPSGCRM KGLIDEVNQDFTNRINKLKNSLFDYQKNNKDSSSLTTNIMELVRGDFATANNNDNTYSQVSEDLRSKIEI LRRKVLEQVQHIHLLQKNVRDQLVDMKRLEVDIDIKIRSCQGSCSRALERRTDLKYYEDQQKQLEQVIAK DLLPPKDRQYLPLLKTSPAPNMLPGDYKSQLQEAPLEWKALMEMKQMKMTLERLDRDGNARGDTPSHGTG SVPESPRNPGSSTPGSAGTWNPGSTGPGSAGPWSSGSTRPGSTGPGSAGTWSTRPGSTGPGSAGTWSTRP GSTGPGSAGTWSSGSTGPGSTGPGSTGTWSSGSTGPGNTGPGSTGTWSSGSTGPGNTGPGSTGTWSSGST GPGNTGPGSTGTWSSGSSDSESFRPGSVGHGNTRPTNPEWGTFEEVSGSVTPGLKNEFHTGKLVTSKGEK ELLIGNEKVTSGSTTTTRHACSKTVTKTVIGPDGRKEVTKEVVNSEDGSDCGDLSHTFAGSLDDLHARHP DLERFFGTSIVKTPPGILLPSRKEFEHKTHIMGSDSDIFTNIGTPEFPSSGKTSSHSKQFVTSSTTYNRG DSAFESKSYKGAGEAGTEAEREIFRGEYSIKRGHAKARPARDCDDVLQTHPSGAQSGIFNIKLPGSSKLF SVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLDDKGEGEFWLGNEHLHLLTLRASVLRVELE DWAGNQAYAEYHLRVGSEAEGYALQVSSYEGTAGDALVEGSAEEGTEYTSHAGMQFSTYDRDADQWEENC AEVYGGGWWYNSCQAANLNGIYYPGGSYDPRNNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLETR >XP_005217494.2 fibrinogen alpha chain isoform X1 [Bos taurus] MFSVRDLCLVLSLVGAIKTEDGSDPPSGDFLTEGGGVRGPRLVERQQSACKETGWPFCSDEDWNTKCPSG CRMKGLIDEVDQDFTSRINKLRDSLFNYQKNSKDSNTLTKNIVELMRGDFAKANNNDNTFKQISEDLRSR IEILRRKVIEQVQRINVLQKNVRDQLVDMKRLEVDIDIKIRSCKGSCSRALEHKVDLEDYKNQQKQLEQV IAINLLPSRDIQYLPLIKMSTITGPVPREFKSQLQEAPLEWKALLEMQQTKMVLETFGGDGHARGDSVSQ GTGLAPGSPRKPGTSSIGNVNPGSYGPGSSGTWNPGRPEPGSAGTWNPGRPEPGSAGTWNPGRPEPGSAG TWNPGRPEPGSAGTWNPGRPEPGSAGTWNTGSSGSSSFRPDSSGHGNIRPSSPDWGTFREEGSVSSGTKQ EFHTGKLVTTKGDKELLIDNEKVTSGHTTTTRRSCSKVITKTVTNADGRTETTKEVVKSEDGSDCGDADF DWHHTFPSRGNLDDFFHRDKDDFFTRSSHEFDGRTGLAPEFAALGESGSSSSKTSTHSKQFVSSSTTVNR GGSAIESKHFKMEDEAESLEDLGFKGAHGTQKGHTKARPARDCYDVLQTRPSGAQSGIFSIKLPASSKIF SVYCDQETGLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEYLHLLTLRGSILRVELE DWAGKGAYAEYHLRVGSEAEDYALEVSSYKGTAGDALIEGSVEEGTEYTSHTGMRFSTFDRDADKWEDNC AEVYGGGWWYNNCQAANLNGIYYPGGSYDPRDNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLVTQ >XP_002716943.1 PREDICTED: fibrinogen alpha chain [Oryctolagus cuniculus] MFSMKILCLLLCAVGTVWTVDPGESTFIDEGATGRGPRVVDKPPSSCKEADWPFCADDDWNQKCPSGCRM KGLIDEMNQDFTDRMNKLRNSLFDYQKNNKDSSSVVTNIMEYLRGNLATANNYDTTYNQVSEELRRRIEV LQRKVIEKVQHIKLLQNNVRAQLIDMKRLEVDIDIKIRSCQGSCNRVLSHEVNLKDYEDQQKQLEQVIAK DLLPPPDRQYLPTIKMTPVADLVPGEYKSQLQKAHPEWKALTEMKQMKVVVEKSGRGETARGDSASFGTG SETGSHRNPGHGSEGPWPTGSSGSSTSHWTSGSFGSGNVGTRNPGISGHGSIRPDSSGHGSTRPTHPDWG TFEEISGNVSPGTKKEFHTEKLVTSKGDKEMLISNERATSGSSSSTSTVRRSCSKTITKTVTGPDGHKQV VKEVVHSEDGSECPEVPDLDSMHSFMSRGSLDDFSFRHPGEASFFDTSSTGKASTFPGLLSTSFKEFGSK SQSMGSESDFFTDAEGAGSHHTSFPSSGKTTTHRKQIVTSHTAFNRGGSTVESKSYKMADEAGGEADQEL RHTHTSRRTHAKVRPSRDCDDVLQTHPSGAQSGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSL NFNRTWQDYKRGFGSLNDKGEGEFWLGNDQLHLLTLRASVLRVELEDWDGRGAYAEYHFRVGSEAEGYAL QVSSYEGTAGDALIEGSVEEGAEYTSHNSMQFSTFDRDADHWEENCAEVYGGGWWYNNCQAANLNGIYYP GGPYDPRNNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLRTP >XP_002815279.3 fibrinogen alpha chain isoform X1 [Pongo abelii] MFSVRILFLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDWNYKCPSGCRM KGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSNSLTTNIMEILRGDFSSANNRDNTYNRVSEDLRSRIEV LKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCSRALAHEVDLKDYEDQQKQLEQVIAK DLLPSRDRQHLPLIKMKPVPDLVPGNFKSQLNKAPPEWRALTDMPQMRMELERPGRNEVTRGDSTSYGTG SEMESPRNPSSAGSWSPGSSGPGSTGNRNPGSSGTGSTGTWNPGSSGTGSTGTWKPGSSGTGSTGTWKPG SSGTGSTGTWKPGSSGSGSTGAWNSGSSGTVSTGNQNPGSPRPGSTGTWNPSSSGHGSAGHWSSESSVSG STGHWHSESGSFRPDSSGSGNMRPTNPDWGTFEEVSGNVSPGTKREYHTDKLVTSKGDEELTTGKEKVTS GSTTTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEGIDLGTLSGIGTLDEFRHRHPDEAAFFE TASTGKTFPGFFSPMFREFVSETESMGSESGIFTNTKESSSRHPGIAEFPSSGKTSSHSKQFITSTSYNR EGSTFESKSYKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIFSV YCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQRGSVLRVELEDW AGNKAYAEYHFRVGSEAEGYALQVSSYEGTAGDALIEGSVEEGTEYTSHNNMQFSTFDRDADQWEENCAE VYGGGWWYNNCQAANLNGIYYLGGSYDPRNNSPYEIENGVVWVSFRGADYSLRAVRMKIRPPATQ >XP_003205398.1 fibrinogen alpha chain [Meleagris gallopavo] MIPLRILCVLLCLNLAWAQDGETTFEKEGAAGRGPRIVEHMHQSSCKYEKNWPMCVDDDWGIKCPSGCRM QGIIDDTNQDNSHRIEKIRQQLADSQNNYKTSNRVIVETINILKPGLEGAQQLDENYGHVSAELRRRIVT LKQRVANQVNRIKALQNSIQEQVVEMKRLEVDIDIKIRACKGSCARSFDYQVDKEGYDNIQKQLTQASSI DMHPDFQATTLSTLKMRPLKDSNVPEHFKLKPPPEMQALNVFNNIKQMQVVLERPETDSRPSQGETFYHV AEARGDSSPPHTSKLVTSAHGRETPSLVDKTSSVHRCTRIVTKKVISSPDGPREEIVEKMVSSDGSDCSH LQGGREGSTYHFSGTGDFHKLDRFQPDLESFFTHDSATGSRHSVSSSTTTTSSRVTGAGSSHLGTGGKDK FTDLGEEEEDDFGGLQPSGFAAGSASHSRTVVTSSSSSFNKGGSTFETKSLKTREISERLGGVQHDQSAE DTPDFQARSFRQAAMSTRRDYSGKDCDDIRQKHTFGAKSGIFKIKPEGSSKVLSVYCDQETTLGGWLLIQ QRMDGSVNFNRTWQDYKRGFGSVDGKGRGELWLGNENIHLLTQNDTLLRVELEDWDGNAAYAEYIMQVGT EAEGYALAVSSYEGTAGDALVAGWLEEGSEYTSHAQMQFSTFDRDQDRWEESCAEVYGGGWWYNSCQAAN LNGIYYPGGHYDPRYNVPYEIENGVVWIPFRASDYSLKVVRMKIRPLDTL >XP_020957142.1 fibrinogen alpha chain isoform X1 [Sus scrofa] MGWDVAAETILSSSRSAPPERAPPLAKMFSVRLFCLVLTVVGTVQMAEVQDKGEFLAEGGGVRGPRLTER HQSACKESDWPFCSDEDWNIKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFDYQKNNKDSSTLSRNIIEL LRGDFSNANNNDNIYSQVSEELRSRIEILKRKVLEKVQHIHLLQKNVRDQLIEMKRLEVDIDIKIRSCKG SCSRALEHKVDLKDYENQQKQLDQVIAINLLPSRDRQYLPLIKISPLPDITPADFKTQARETPPEWKALL ETRQVKMVLERVGGDERTRGGSISHGPGSVPGTGSPGGLKPGSYGPGGPGTWKPGRPEPGSTGTWDSGHP DPGSAGTWKPGRPEPGSTGTWDSGHPDPGSAGTWKPGRPEPGSTGTWDSGRPDPGSAGTWKPGRPESGST GTWHSEHLEHGSSSTWHSGQHEHGSVGSWKPGSSGSGSLRPDSSGPGDTTPSNPDWGTFKEVSGSVSPGT KSEVHTSKLVTSKGDKDIVIGKEKVTSGHTSTTHRSCSKTITKTVTKADGRTETIKEVINSEDGSDCGGT DVEFAHMLPGKGSLDEFFHRHRDETSLSRDPFPDFFSPVLKEFDGKTHPGGPGSDLAGFFHPDGPEYSSS SKISSHSKQTITKTINREGGAVESKSYKMEDEADSEEGLDLKGGHVIKRVYTRTRPARDCGDALQTHPSG AQSGIFNIELPGSSKIFSVYCDQETDLGGWLLIQQRTDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNE YLHLLTLRGSVLRVELEDWAGKGAYAEYHLRVGSEAEGYALQVSSYKGTAGDALIEGSPEEGSEYTSHAG MQFSTFDRDADKWEENCAEVYGGGWWYNNCQAANLNGIYYTGGSYDPRDNSPYEIENGVVWVPFRGADYS LRAVRMKIRPLVTP >XP_003822627.2 fibrinogen alpha chain [Pan paniscus] MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDWNYKCPSGCRM KGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSANNRDNTYNRVSEDLRSRIEV LKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCSRALAREVDLKDYEDQQKQLEQVIAK DLLPSRDRQHLPLIKMKPVPDLVPGNFKSQLQKAPPEWKALTDMPQMRMELERPGRNEITRGDSTSYGTG SETESPRNPSSAGSWNPGSSGPGSSGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPG SPRPGSTGTWNPGSSEHGSAGHWTSESSVSGSTGQWHSESGSFRPDSSGSGNGRPTNPDWGTFEEVSGNV SPGTRREYHTEKLVTSKGDKELTTGKEKVTSGSTTTTRRSCSKTVTKTVIGHDGHKEVTKEVVTSEDGSD CPEAIDLGTLSGIGTLDEFRHRHPDEAAFFDTASTGKTFSGLFSPIFREFVSETESRGSESGIFTNTKES SSHHPGIAEFPSRGKTSSHSKQFTSGTSYSRGGSTFESKSYKMADEAGSEADHEGTHSTKRGHAKSRPVR DCDDVLQTHPSGTQSGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLN DEGEGEFWLGNDYLHLLTQRGSVLRVELEDWAGNEAYAEYHFRVGSEAEGYALQVSSYEGTAGDALIEGS VEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENG VVWVSFRGADYSLRAVRMKIRPLVTQ >XP_019684378.1 fibrinogen alpha chain [Felis catus] MFSLKIFCLALSVVGTVWTGDVQEGEFIAEGGGVRGPRIVEGHHSVCKETDWPFCSDEDWNYKCPSGCRM KGLIDEVNQDFTNRINKLKNSLFDYQKNNKDSSLLTGNVMELVRGDFATGNNNDNTFSQVSEDLRSRIEI LKRKVLEQVQHIQLLQKNVRDQLIDMKRLEVDIDIKIRSCQGSCSRALERRTDLKYYEDQQKQLEQVIAK DLLPSRDTQYLPLLKMRTAPDMIPGEYKHQLQKAPAEWKALMETQQMKITLERSGTDGNAPGDSASHGTG SVPESPRNPGSSTPGSSGTWNPGSSGPGSSGAWNPGSTGPGSSGAWNPGSSGPGSSGAWNPGSSTPGSSG AWNPGSSGPGSSGPGSSGAWNPGSSGPGSSGAWNPGSSGPGSGSTWNAGSSGVSSAGTWNTESASSWSTG TGSGGSWSSGTPQPGSFRPDSLGHGDTRPTKQEWGTVEEVSGSVSPGTKKEYHTGKLITSKGDKELLIGN EKVTSGSTTTTHRSCSKTVTKTVIGPDGRKEVIKEVVNSEDGSDCDLSHAFSGSLGDLHSRHPDLASFFE SASTGSKFSSVLTPTLREFESMGSESDIFTHLGEHELPSSGKTSTHSKQLVTTSKTYNRGDSTFESKSFK VAGEAGSEAEHEVLRGAYTTKRGHARARPARDCDDVLQTHPAGAQSGIFNIKLPGSSKIFSVYCDQETSL GGWLLIQQRMDGSLNFNRTWQDYKRGFGSLDDKGEGEFWLGNEYLHLLTLRGSVLRVELEDWAGNLAYAE YHLRVGSEAEGYPLQVSSYQGTAGDALIEGSVEEGTEYTSHAGMQFSTYDRDADLWEENCAEVYGGGWWY NSCQAANLNGIYYPGGSYDPRNNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLVTHSEQK >XP_004017232.4 fibrinogen alpha chain [Ovis aries] MFSVRDLCLVLSLVGAIQTADDSDPVGGEFLAEGGGVRGPRLVEKQQSTCKETGWPFCADEDWGEKCPSG CRMKGLIDEVNQDFTGRINKLRDSLFNYQKTNKDSNTLTKNIVEILRGDFAKANNNDNTFNQVSEDLRSR IEILRRKVIEQAQHINLLQKNVKNQLVDMKRLEVDIDIKIRSCKGSCSRALEHKVDLEDYKNQQKQLEQV IAINLLPSRDTQYLSLIKMSAVTGPVPRELKSQLREAPPEWKALLEMQQMKMVLENFGGDGHARGDSVSH RTGLAPESPRKPGTGSIGNVNPGSYGPGSSGTWSPGHPEPGSAGTWNTGRPEPGSAGTWNTGRPEPGSAG TWNTGRPEPGSAGTWNIGSPEPGSVGIRNTGSSGSSSFRPDSSGHGGNIRPSSPDWGTFREEGSVSSGTK KEFHTGKLVSAKGEKELLIGNEKVSSGHATTTRRSCSKVITKTVTNAEGHTETTKEVVKSEDGSDCGDAD FDWDHTFSTRGNLEDFFHRNSDGFFTHKLHEFDGKTRLESDVPDLREIGSSGSKTSAHSKQFLSSSTTIS RGGSALESKNFKMADEAESIEDLGIKGAHATKTGHAKARPARDCYDVLQTHPSGAQSGIFSIKLPGSSKI FSVYCDQETGLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEYLHLLTLRGSILRVEL EDWAGKGAYAEYHLRVGSEAEDYALEVSSYKGTAGDALIEGSVEEGTEYTSHTGMRFSTFDRDADKWEDN CAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRDNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLVTQ >XP_018880884.1 fibrinogen alpha chain [Gorilla gorilla gorilla] MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDWNYKCPSGCRM KGLIDEVNQDFTNRINKLKNSLLEYQKSNKDSHSLTTNIMEILRGDFSSANNRDNTYNRVSEDLRSRIEV LKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCSRALAREVDLKDYEDQRKQLEQVIAK DLLPSRDRQHLPLIKMKPVPDLVPGNFKSQLQKAPPEWKALTDMPQMRMELERPGRNEITRGDSTSYGTG SETESPRNPSSAGSWNPGSSGPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPG SPRPGSTGIWNPGSSERESAGHWTSESSVSGSTGQWHSESGSFRPDSSGSGNARPTNPDWGTFEEVSGNV SPGTRREYHTEKLVTSKGDKELTTGKEKVTSGSTTTTRRSCSKTVTKTVIGPAGHKEVTKEVVTSEDGSD CPEAMDLGTLSGVGTLDEFRHRHPDEAAFFDTASTGKTFPGFFSPMFGEFVSETESRGSESGIFTNTKES SSHHPGLAEFPSRGKTSSHSKQFTSSTSYSRGGSTFESKSYKMADEAGSEADHEETHSTKRGHAKSRPVR DCDDVLQTHPSGTQSGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLN DEGEGEFWLGNDYLHLLTQRGSVLRVELEDWAGNEAYAEYHFRVGSEAEGYALQVSSYEGTAGDALIEGS VEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENG VVWVSFRGADYSLRAVRMKIRPLLTQ >XP_013227609.1 fibrinogen alpha chain [Columba livia] MISMKILCVLLCLNLAWAQDGETTFEKEGAGVRGPRIVEHMSQSTCQYEKNWPFCADDDWGIKCPSGCRM QGLIDETDKDYSQRIDKIKKLLAENQNNYKKSNRVIVETINVLKPNLDSAQEIDENYGHVSGELRRRIVT LKQRVVTQVNRIKALQSSIQEQVAEMKRLEVDIDIKLRACKGSCARSFDYQVDKESYDNIQKQLTQANSI NLHPELQTTTLSTLKMRPLKDSNVPEHFKHKPLPEMQALNIINNIRQMQAVLERSETDINPSRGDSLYHV SESRGDGHSHTSKLVTPIHERETLSLGGKTSSTVRRCTKTTTKKIVTGPDGPREEVVEKMVSSDGLDCSF LQGAGNVGGEGTTYHVGGTGDLHKLEKLFPELDSFFSPDSPSTAGRPFGGSSSISTSSHLTGTGSSHLGT GVSTHSGTYEGKGKFTDLREDEEDDFGGLHLQPSGFPSGSASHSKTVVTSASSSFNKGGSTFETKSLKTR EITEQLGGVQHDESAEDIPDFQARSFRPSGVKQRTPNTGKDCDDIRQKHTSGAKSGIFKIKPAGSNKVLS VYCDQETTLGGWLLIQQRMDGSVNFNRTWQDYKRGFGSVDGRGRGEFWLGNENIHLLTQNDTLLRIELED WDGNAVYAEYIVQVGSEEEGYALAVSSYEGTAGDALITGWLEEGSEYTSHAQMRFSTFDQDQDHWEESCA EVYGGGWWYNSCQAANLNGIYYLGGHYDPRYNVPYEIENGVVWLPFRASDYSLKIVRMKIRPIETL >XP_005691214.3 PREDICTED: fibrinogen alpha chain [Capra hircus] MFSVRDLCLVLSLVGAIQTADDSDPVGGEFLAEGGGVRGPRLVEKQQSTCKETGWPFCADEDWGEKCPSG CRMKGLIDEVNQDFTSRINKLRDSLFNYQKNNKDSNTLTKNIVEILRGDFAKANNNDNTFNQVSEDLRSR IEILRRKVIEQAQHINLLQKNVKNQLVDMKRLEVDIDIKIRSCKGSCSRALEHKVDLEDYKNQQKQLEQV IAINLLPSRDTQYLSLIKMSAVTGPVPRELKSQLREAPPEWKALLEMQQMKMVLENFGGDGHARGDSVSH RTGLAPESPRKPGTGSIGNVNPGSYGPGSSGTWSPGHPEPGSAGAWNTGSPEPGSAGTWNTGRPEPGSAG TWNTGRPEPGSAGTWNTGRPEPGSAGTWNTGRPEPGSAGTWNTGSPEPGSVGIRNTGSSGSSSFRPDSSG HGGNIRPSSPDWGTFREEGSVSSGTKKEFHTGKLVSAKGEKELLIGNEKVTSGHATTTRRSCSKVITKTV TNAEGHTETTKEVVKSEDGSDCGDADFDWDHTFSTRGNLEDFFHRNSDGFFTHKLHEFDGKTRLESDVPD LREIGSSGSKTSAHSKQFLSSSTTISRGGSALESKNFKMADEAESIEDLGIKGAHATKTGHAKARPARDC YDVLQTHPSGAQSGIFSIKLPGSSKIFSVYCDQETGLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDK GEGEFWLGNEYLHLLTLRGSVLRVELEDWAGKGAYAEYHLRVGSEAEDYALEVSAYKGTAGDALIEGSVE EGTEYTSHTGMRFSTFDRDADKWEDNCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRDNSPYEIENGVV WVPFRGADYSLRAVRMKIRPLVTQ >XP_006034117.1 LOW QUALITY PROTEIN: fibrinogen alpha chain [Alligator sinensis] MLQMRILCILLCLSIVWAVEEGSTFEEEGGVARGPRLSERAQASCKHEKSWPFCSDDQWGQKCPSGCRMQ GLIDDTNSDFNHRLDKIRKLLDDNENKYKKSKIITTETFNSMKGTLVSGQESDSKYGQVIEDLRRRIVSL KTKVIAQIERIYGLQNSIREQVLEMKRMEVDIDIKIRACKGSCVKSSDYHVDKESYDNIQRQLTQASSIN LQSDLSSSIIRVLKIKPMKDSTILPHFKAGDPKDWPEWNFLNKMQQLELVLESPETGPKFFPVDTSYSSS VHKGDGEPQGSKFVHTTYGKETRFGEGVSSSSTHYTCTKTVTKKVVTGPDGPREEVVEKYTSSDGSDCSH LRGLGKEDISGGYNVRVTTGGGGDGMSDLDKVFSFFSTDSESDGSRHSSSSIGGTSSGFINTGTGSERGS GGSSHSRGVQGSDASGELREGEEDWHISELPYSKTQSGVSSETVVSSSTSFNKGGSTFETKSLKTXRLDG FPHDESTEDGPDFKACSFKMDTFFSGPRTTGTDCEDIRQKHTSGAKSGIFRIKPTGSSKVLSVYCDQETT LGGWLLIQQRIDGSVNFNQTWQDYKKGFGSVDAKGKGELWLGNENIHLLTQKDTVLRVELEDWAGNTVYA EYNIHVGSESQGYVLSVSNYEGTAGDALITGSVDEGSEYTSHANMKFSTFDRDSDQWEENCAEVHGGGWW YNNCQAANLNGMYYLGGQYDPRNNIPYEVENGVVWIPFRASDYSLKIVRMKIRPNKTL >XP_043340007.1 fibrinogen alpha chain [Cervus canadensis] MFSMRDLCLVLSLVGAVQAADGSDPASSDFLAEGGGVRGPRLVERQQSTCKETGWPFCADEDWGEKCPSGCRMKGLIDEV NQDFTSRINKLRDSLFNYQKNNKDSNTLTKNIVELLGGDFAKANNNDNTFNQVSEDLRSRIEILRRKVIEQVQYINLLQK NVRDQLVDMKRLEVDIDIKIRSCKGSCSRALEHKVDLEDYKDQQKKLEQVIAIDLLPSRDVQYLPLIKMSAITGPVSREF KKQLQEVPSEWKALLEMQQTKMVLETFGGDGHARGDSVSHGTGLAPERPRRPGTSSIGNVNPGSYGPGGSGTWNTGRPEP GSAGTWNTGRPEPGSAGTWNTGRPEPGSAGTWNTGRPEPGSAGTWNTGSSGSSSFRPDSSGHGNTRPSSPDWGTFREEGS VSSGTKKEFHTGKLVTTKGEKELLIGNEGVSSGHTTTTRRSCSKVITKTVTNADGRTETTKEVVKSEDGSDCGDADLDWH RTLSVRGNLDDFFSRNNDGFLTHKLREFDGKTGLESGVPALEEFGSSSGKTSTQSKQFVSSSTTINRGGSAIESKSFKMA DEAESVEDLGLKGAHATQKGHAKARPARDCYDVLQTHPSGAQSGIFSIKLPGSSKIFSVYCDQETGLGGWLLIQQRMDGS LNFNRTWQDYKRGFGSLNDKGEGEFWLGNEYLHLLTLRGSILRVELEDWAGKGAYAEYHLRVGSEAEGYALEVSSYKGTA GDALIEGSVEEGTEYTSHTGMRFSTFDRDADKWEDNCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRDNSPYEIENGVV WVPFRGADYSLRAARMKIRPLGHNRLTGWE >XP_043758605.1 fibrinogen alpha chain [Cervus elaphus] MFSMRDLCLVLSLVGAVQAADGSDPASSDFLAEGGGVRGPRLVERQQSTCKETGWPFCADEDWGEKCPSGCRMKGLIDEV NQDFTSRINKLRDSLFNYQKNNKDSNTLTKNIVELLGGDFAKANNNDNTFNQVSEDLRSRIEILRRKVIEQVQYINLLQK NVRDQLVDMKRLEVDIDIKIRSCKGSCSRALEHKVDLEDYKDQQKKLEQVIAIDLLPSRDVQYLPLIKMSAITGPVSREF KKQLQEVPSEWKALLEMQQTKMVLETFGGDGHARGDSVSHGTGLAPERPRRPGTSSIGNVNPGSYGPGGSGTWNTGRPEP GSAGTWNTGRPEPGSAGTWNTGRPEPGSAGTWNTGRPEPGSAGTWNTGRPEPGSAGTWNTGSSGSSSFRPDSSGHGNTRP SSPDWGTFREEGSVSSGTKKEFHTGKLVTTKGEKELLIGNEGVSSGHTTTTRRSCSKVITKTVTNADGRTETTKEVVKSE DGSDCGDADLDWHRTLSVRGNLDDFFSRNNDGFLTHKLREFDGKTGLESGVPALEEFGSSSGKTSTQSKQFVSSSTTINR GGSAIESKSFKMADEAESVEDLGLKGAHATQKGHAKARPARDCYDVLQTHPSGAQSGIFSIKLPGSSKIFSVYCDQETGL GGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEYLHLLTLRGSILRVELEDWAGKGAYAEYHLRVGSEAE GYALEVSSYKGTAGDALIEGSVEEGTEYTSHTGMRFSTFDRDADKWEDNCAEVYGGGWWYNNCQAANLNGIYYPGGSYDP RDNSPYEIENGVVWVPFRGADYSLRAARMKIRPLGHNRLTGWE >KAB0370205.1 hypothetical protein FD755_018167 [Muntiacus reevesi] MQETQEMQVQCLAADGSDPASGEFLTEGGGVRGPRLVERQQSTCKETGWPFCADEDWGEKCPSGCRMKGLIDEVNQDFTS RINKLRDSLFNYQKNNKDSNTLTKNIVELLGGDFAKANNNDNTFNQVSEDLRSRIEILRRKVIEQVQHINLLQKNVRDQL VDMKRLEVDIDIKIRSCKGSCSRALEHKVDLEDYKDQQKTLEQVIAIDLLPSRDVQYLPLIKMSAATGPVSREFKKQLQE VPSEWKALLEMQQTKMVLETFGEDGHARGDSVSHGTGLAPERPRRPGTSSTGNVNPGSYGSGGTRKCWHLXXXAGTWNTG RPEPGSAGTWNTGSSGSSSFRPDSSGHGNTRPSSPDWGTFREEGSVSSGTKKEFHTGKLVTTKGEKELLIGNEGVSSGHT TTTRRSCSKVITKTVTNADGRTETTKEVVKSEDGSDCGDADLDWHRTLSVRGNLDDFFSRNSDGFFTHKLHEFDGKTGLE SGVPALEEFGSSSGKTSTQSKQFVSSSTTINRGGSAIESKSFKMADEAESVEDLGLKGAHATQKGHAKARPARDCYDVLQ THPSGAQSGIFSIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEYLHLL TLRGSILRVELEDWAGKGAYAEYHLRVGSEAEGYALDVSSYNGTAGDALIEGSVEEGTEYTSHTGMQFSTFDRDADKWED NCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRDNSPYEIENGVVWVPFRGADYSLRAARMKIRPLGHNRLTGGE >KAB0358664.1 hypothetical protein FD754_002820 [Muntiacus muntjak] MQETQEMQVQCLAADGSDPASGEFLTEGGGVRGPRLVERQQSTCKETGWPFCADEDWGEKCPSGCRMKGLIDEVNQDFTS RINKLRDSLFNYQKNNKDSNTLTKNIVELLGGDFAKANNNDNTFNQVSEDLRSRIEILRRKVIEQVQHINLLQKNVRDQL VDMKRLEVDIDIKIRSCKGSCSRALEHKVDLEDYKDQQKTLEQVIAIDLLPSRDVQYLPLIKMSAVTGPVSREFKKQLQE VPSEWKALLEMQQTKMVLETFGEDGHARGDSVSHGTGLAPERPRRPGTSSTGNVNPGSYGSGGTRKCWHLXXXAGTWNTG RPEPGSAGTWNTGSSGSSSFRPDSSGHGNTRPSSPDWGTFREEGSVSSGTKKEFHTGKLVTTKGEKELLIGNEGVSSGHT TTTRRSCSKVITKTVTNADGRTETTKEVVKSEDGSDCGDADLDWHRTLSMRGNLDDFFSRNSDGFFTHKLHEFDGKTGLE SGVPALEEFGSSSGKTSTQSKQFVSSSTTINRGGSAIESKSFKMADEAESVEDLGLKGAHATQKGHAKARPARDCYDVLQ THPSGAQSGIFSIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEYLHLL TLRGSILRVELEDWAGKGAYAEYHLRVGSEAEGYALDVSSYNGTAGDALIEGSVEEGTEYTSHTGMQFSTFDRDADKWED NCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRDNSPYEIENGVVWVPFRGADYSLRAARMKIRPLGHNRLTGWE >NP_001080329.1 fibrinogen alpha chain precursor [Xenopus laevis] MTQWAALITLLLCFAGSVWSEGEGGIEAQGGSIRGPRIMESKAESDCKQEKNWPICSDEDWGPKCPSGCRIQGLTDKTDK DFAKRIETIKQKFKDGEISYKSIDVQTKQTYENLKNNLIQAQQSDGKYNQASEDLRKKIEYLKLKVSNQVERIKSLQRNI RDQVVEMKRLEVDIDIKIRACKGSCAKNTDYKVDLDSYNNIQKLLLQAETTDLSNEMNSIRVLKMKPIKDSPVDSRYKTL ALDKDQEAEFPIFKDINQYSFVLEGTKEEVKGSSIGTSSVVFPSGSGKDVDFQGSKGTQSGTVKGGDQSTKVITESRTVS CTKTKKKRVIITPEGPKEEIIESYSGGAECEKLGKFSTGDTFEAGSDGTRVIKISGSSSLGDISKIPSFEEFLSSSGKKT QTSQTSSSSSSSSSSTYSKGVTHDAFSDLGEDEFDDFSHTGLDSPSFTPIQKEGSSTYTKTVVSSSSRGSTKDGTQFDIK SMKSGPVFDDFGPIQHDNSEEDRPDFQARTVRKETKLVGDYTGKDCDDIRQKHSSGAKSGIFKIRPEGSSKVLTVYCDQD TQLGGWILIQQREDGSVNFNRTWQDYKNGFGSVDASGKGEVWLGNENIHLLTQKDTFLRIELEDWSGEKAYAEYNFQLGS ESEGFILKVSQYEGTAGDALIEGSKEDGEYTSHFNMKFSTYDRDSDKWEENCAEMYGGGWWYNNCQASNLNGIFYIGGQY DPRNSVPYEIENGVVWVPFKAADYSLKTVRMKIRPVETSG >XP_040187953.1 fibrinogen alpha chain-like [Rana temporaria] MLRATLVTVLLCLASTAWTAEDFEDVGATGRGPRILEQKAAAGCKQEKNWPVCSDEDWGPKCPSGCRVQGLTTQTDKEFS KRIDAIKQKLKDGESNYKSIDVRTKETYELVKGNLVAAQQTDGAYNQVTENLRRKIEFLKTKVTIQIDRIKLLQKNIRNQ VVEMKRLEVDIDIKLRSCKGSCAKGVEYNVDYESYENIQKQLLQAESTDLRPNVNAIPVLKMRPIKDEAVTDSRYKTLAQ QKEQYPIFSDIKQYSFVLEGKSKEVSGQPVSTSSVSGSTKEQPTQTFVIYGDKGTQPVKVSGGDKTSVTTESRVITCTKT ITKKIVRGPDGPREEVFETTSGDECEKLEALKKEGKGEFDADGTYTVKVTGSGSAGGVHIPSWDDFLSGKQVSGSSASSG SSTSKTQSSSTKTQTSFTNGEDEFDDFSHVDLGAPSFQPIKTQSSSGSTTYSKTVVSSSSGSTKDGTEWGTKYKSGPVFE DLGPILEGNSEEDVPDFSARSVRPGVKKTSSSTGSDCADILQKHSSGGKSGIFKIKPEGSQTELSVYCDQDTQIGGWLLI QQREDGSVNFNRTWQDYKHGFGSVDANGKGELWLGNKYIHMLSQNETILRVELEDWSGKQAFAEYIFRLGSESEGFALHA SSYEGLAGDALTEGSKEDSENTSHDKMKFSTYDRDNDKWEENCAEMYGGGWWYNNCQAANLNGIYYTGGQYDPRNNVPYE IENGVVWLSFKPDDYSLKTVKMKIRPVETA >NP_001181918.1 fibrinogen alpha chain precursor [Danio rerio] MKFTHSLLCLFVAVSSALAEEDTVVNPRGARPIEHGFKAQDTCQTKEWPGCTDDDWGSKCPSGCRVQGLMDKADHDLLKK IEKIRRLLVEGQKLYRSADEVSKTTYTYLREKLTSNSGYDNRYMSLAEQLRQRITDIKIKIDRQLRLLDALKSQVKDQVV VMQRLEVDIDIKLRTCKGSCASYSEFSVDRESYVTLDKQMDNLNAMRVQSVETVSSLGIMKSRPLKDVLVPTIYKSGTGK AEQKLLFGDVGQMQLSLEAEGSTAESAATVSKFPTSGTGSTSQTSSKQCTKSVRKVITHTKDGPVEKVEVSSSGPGCDDL GKLGISDSEFLTAAKDGKDLSRDGLKITVTGGDEKSLTSLSHSTSDLGGFGGDFFKNLGTDNRKYASSSSSTSTKTVSDG SKSYSKTTLTSDPIFGDDLGAFMRGDVEEDMPDIHARSVKSQDDRKAGFVGGDCVEIQQKHVNGGQSGMFKIKPAGSEEV VEVYCDQSTGLGGWTLVQQREDGSVNFNRTWKEYLNGFGQIDKQGKGEIWIGNKFLHLLTQKESLLRVELQDWTGAEAYA EYNIKVGSEAEGFPLTASDYDGDAGDALVRGHPNLGSFLSHAGMKFSTFDRDSDKWEENCAEMYGGGWWYNNCQSANLNG IYYKGGQYDPATKVPYEIENGVVWLPFKPADYSLKVVRMKIRPV >XP_030287455.1 fibrinogen alpha chain-like isoform X1 [Sparus aurata] MQRLGLLVCFIIGVTQSAVQVDPRGARPVEHGTRSEKCASEKEWPFCTTDEWGPKCPSGCRIEGLMNKYDHSLLKRIEKI RSLLDENTVKQRSTDSATKQTYDYLKDKLTTDAGHNNNYYDLAQNLRQRITDMKIKIDRQLRILAALKDRVKDQVVEMQR LEVDVDIKLRSCKGSCQGYAEFQVDHEDYVVLDKQINQLDSQSAQRIDSVKTLYVMKSRPLKESNVDSIYKSSDTTGAVA AQRREDVFTDVPMVQLLLGEEGSSSSPATISKDQGTSYSSPTFSSSSSSSSSSSSSSSSSSSSTPSKSITELGGSSHLFG TDGGIQGLGGSATTHMSTQTISCTKSTRRTIVHTKDGPVEKVEEVYEGGPECQALGDSSKGGMGAFFPTLTHTGGAKGSL LGNTKTGFENPFGAEGLDLGGFMKDNTEDDIPDFHARSVKSSRVERQADYVGKDCVEAYQNHLKGETNGLFNIRPGGTDS TQVVEVYCQQEGLMGGWMLVQQRENGALSFNRTWAEYRTGFGSVDAKGKGELWLGNQNLHLLTNQGETMLKVELEDWEGG VAIAEYIIRVGSEEEGYPLHVSGYTGDAGDALVMPKSDMASYLSHNGMKFSTFDKDNDRWEENCAEMYGGGWWYNNCQSA NLNGMYYQGTYDPEKNKPYEIENGVVWVTYKTANYSLKTVRMFIRSSAF >XP_015801603.1 PREDICTED: fibrinogen alpha chain [Nothobranchius furzeri] MKMMRLLVCLVCVAVTQVASQVDPRGARPVEPATRSDKCSTQKEWPFCTDDDWLSKCPSGCRIQGLMDKADHELLKKIEK IRSLLNQNKAKHRSTDQVSKQTYDYLRDRLTTDSGNNNNYYDLAQSLRQRITDMKIRIDNQMNTLAALKNRVKNQVTEMQ RLEVDIDIKLRSCKGSCGGYSEYQVDKESYVNLDKQMRQLEAQSAQSVESVGTLYVMKTSSLQTAAAETRFKSKDVGGQK KDDVFSEVKTLQFVLEQEGSSSSPATVSKEPGTSQLQGTPAPLLPSSSSSSSSSKYITQLGGPGDFPGGFGTFDNSGQDR VYYGSTKTSSCTKSIKRTVVLTKDGPVEKTEEVMQGGPECRGMTELTKGGMSSLFPTLTHTSSSSSSSLTHTSSSSSGGA KGSLLGDSKLGFMDPFRDDGFDLGAFMPDNAEDDVPDFHARSVKSAPVQRQDDFVGKDCVDAYQKHLKGETNGLFKIKPG GTDSTVVEVYCHQEGIMGGWLLVQQRASGSVSFNRTWAEYRDGFGSVDAEGNGEFWLGNQLLHLLTNQSETMLKVELEDW EGGAATAEYSVRVGSKEEGYPLHVSGFTGDAGDALLKSHSGMKFSTFDKDDDKWERNCAEVYGGGWWYNSCQLANLNGVY YRGSYDPKGSAPHQAENGVVWTTFKPATYSLKAVRMFVRPAEF >XP_011485484.2 fibrinogen alpha chain [Oryzias latipes] MGCWSRCSTLMRPDGRRLSGESQLWWRPSKDVTAAAQMQSDTEERRMKQLVVLTCLLCVAFTQDTVIDPRGARPVEHGTR DEKCATQKEWPFCLDDDWGHKCPSGCRIQGLMDKYDHDLLKRIEYIRDQLNQHKGKYRSADQVSKQTHDYLREKLTVDAG HDNKYFELAQSLRQRITEIKIRIDRQMKVMAALKGRIREQVTEMQRLEVDIDMKLRSCKGSCATYHEYQVDQQSYVTLEK QVAQLDSQTPQNIEAAGTLYVMKSRPLKDLQVDSIYKSKAVQGQQKQDLFSDIKTLKLVLEEEGSSSSPATVSKEPGTPF PSTSSSSSSSSSSSSGSSNPSKSITELGGRGDTDFFGGGLGGFGGFSQASTGSVTTKSVSCTTHMKKVVVQTKAGPVERY ETVTEGGPECQGGADLTKGGLTSLFPSLSHTSSSMSTKSGFSSGAKGGLLGNPFEGDLGSDLGAFMTDNAEDDLPDFHAR SLGSTVVNRQADYVGKDCVEANQKHLKGETNGLFKIKPGGADSTQVVEVYCQQEGVMGGWLLVQQRESGALSFNRSWADY RGGFGSVDAQGKGEFWLGNENLHLLTSQGETILKVELEDWEGGKASAEYTMRVGSEQEGFPLHVSGYTGDAGDSLAAPTS EKASEVTHDGMKFSAFDKDNDNWGENCAEAYGGGWWYNSCQAANLNGVYYKGEYDPATNTPYKTENGVVWSSFKPVNYSL KTVRMLIRSAAF >XP_006275580.1 PREDICTED: LOW QUALITY PROTEIN: fibrinogen alpha chain [Alligator mississippiensis] MLLKMLQMRILCVLLYLSIVWAVEEGSTFEDEGGVARGPRLSERAQASCKHEKSWPFCSDDQWGQKCPSG CRMQGLVDDTNSDFNHRLDKIRKLLDDNENKYKKSKIITTETFNSMKGTLVSGQESDSKYGQVIEDLRRR IVSLKTKVIAQIERIYGLQNSIREQVLEMKRMEVDIDIKIRACKGSCAKSFDYHVDKESYDNIQRQLTQA SSINLQSDLSSSIIRVLKIKPMKDSTVLPHFKAGDPKDWPEWNFLNKMQQLELVLESPETGPKFFPVDTS YSSSVHKGDGEPQGSKFVHPTYGKETHFGEGVSSSSTHYTCTKTVTKKVVAGPDGPREEVVEKYTSSDGS DCSHLRGLGKEDISGGYNVRVTAGGGGDGMSDLDKVFSFFSTDSESDGSRHSSSSIGGTSSGFINTGTGS ERGSGGSSHSRGVQGSDASGELREGEEDWHISELPYSKTQSGVSSETVVSSSTSFNKGGSTFETKSLKTX RLDGFPHNESTEDGPDFKSRSFKMDTFFSGPRTTGTDCEDIRQKHTSGAKSGIFRIKPTGSNKVLSVYCD QETTLGGWLLIQQRIDGSVNFNQTWQDYKKGFGSVDAKGKGELWLGNENIHLLTQKDTVLRVELEDWAGN TVYAEYNIHVGSESQGYVLSVSNYEGTAGDALITGSVDEGSEYTSHANMKFSTFDRDSDQWEENCAEVHG GGWWYNNCQAANLNGMYYLGGQYDPRNNIPYEVENGVVWIPFRASDYSLKIVRMKIRPNETL >XP_020747240.1 fibrinogen alpha chain [Odocoileus virginianus texanus] MFSVRDLCLVLSLVGAFQAADGSDPAGGEFLAEGGGVRGPRLVERQQSTCKETGWPFCADEDWGEKCPSG CRMKGLIDEVNQDFTSRINKLRDSLFNYQKNNKDSNTLTKNIVELLGGDFAKANNNDNTFNQVSEDLRSR IEILRRKVIEQVQHINLLQKNVRDQLVDMKRLEVDIDIKIRSCKGSCSRALEHKVDLEDYKDQQKKLEQV IAIDLLPSRDVQYLPLIKMSPVAGPVSREFKRQLQEVPQEWKALLEMQQTKMVLETFGGDGHARGDSVSH GTGLAPERPRRPGTSSIGNVNPGSYGPGGSGTWNTGHPEPGSAGTWNTGRPEPGSAGTWNTGRPEPGSAG TWNTGRPEPGSAGTWNTGSSGSSSFRPDSSGHGNTRPSSPDWGTFREEGSVSSGTKKEFHTGKLVTTKGE KELLIGNEGVASGHTTTTRRSCSKVITKTVTNADGRTETTKEVVKSEDGSDCGDADLDWHRTLSVRGNLD DFFSRNSDGFFTHKLHEFDGKTGLESGVPALEEIGSSSGKTSTQSKQYVSSSTTINRGGSTIESKSFKMA DEAESVEDLGLKGAHAAQKGHVKSRPARDCYDVLQTHPSGAQSGIFSIKLPGSSKIFSVYCDQETGLGGW LLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEYLHLLTLGGSILRVELEDWAGKGAYAEYHL RVGSEAEGYALEVSSYKGTAGDALIEGSVEEGTEYTSHTGMRFSTFDRDADKWEDNCAEVYGGGWWYNNC QAANLNGIYYPGGSYDPRDNSPYEIENGVVWVPFRGADYSLRAARMKIRPLGHNRLTGWE >XP_031552222.1 angiopoietin-2-like [Actinia tenebrosa] MISPPHLIVNESQSALFHYSIRGNPQPLFGWSKVGGSLDTTRSIVNSSRGILEIKHVTFSDSGIYQCNASSIJGKALATT RLVVNYRPRVSLKKGPIYVKIGDNVTLPTCHVMGHPKPRVTWSRSIGKLPSNRTLTRDNELTLFNVVKDDSGTYVCTSDN FLGSDAAGCVLVVVQLPVFVVRPPNISYAIVGSSLTLNCSAKGDPEQVISWRRENGALPSGRYEITPNGSLVLRNIQASD DDIYVCSATSAGVFDVQVKSTLNIFYHDCSEIYKSGERRSGVYTIKPDSERAFQVYCDMTTDGGGWTVFQRRQDGSVDFY RDWQQYKTGFGNLNGEFWLGNDYIHRLTEKTPSVLRVELEDWNRNKKYAKYGSFSVGDESDKYRLKVASYSGDAGDSLIS HHNNLFSTKDRDNDKHQSKCTTLFGGAWWYRACYDSNLNGKYFGNKRDEKGIAWEGFHYDLSLKYSEMKIRPISF >XP_039268423.1 angiopoietin-related protein 2-like [Styela clava] MSRIVVVTLFIALLFCGHVRSQLTVVDPPIMQIATGGDNNGKSNMKYDVKIRKYTVVRVPETPPSTTTEISTTTTTPPPD LDVNHIEVQTRSTFEENLLEEDHDCAFTFTLPNPRPSNQQVCVRDVRALMTSYPEERRSGDEEALNTLRNEISLWQESMG DLKTQIEERLAVPSLEPVRNDVRLLQKESRNMNFRISQLYMQLLHEIIRKRDDTIEYTSVENSVMNVTIKYYELKEKHEA LVTDHKALKQQSQSQQEQIKILQTKMEEMVHRMNRMAVDIQLMGIDDEKDEVNDTANSSLSESRSSYTNCVDIQLYASKE SGIYILTLPSLSRKMKVWCDFEQDPGGWTVIQRRSEGKVNFYRNFASYQRGFGSLEGEFWLGLENIHHLTNQPGVNYKLH IDMEDWSGRKTFVEYGSFKLEGQDEGYRLKVAHYSGTAGDSLTWHNNMKFTTKNVDNDPFARNCANYQKGGWWYNTCAHS NLNGVYYMGGHYRSKFQDGIYWSEWRGGSYSLKHVEMKIKPSE
Mafft alignment of selected proteins >sp|P02671|FIBA_HUMAN Fibrinogen alpha chain OS=Homo sapiens OX=9606 GN=FGA PE=1 SV=2 ----------------------------------------MFS------MRIVCLVLSVV GTAWTADSG---EGDFLAEGGGVRGPRVVER---HQSACK-DSDWPFCSDEDWNYKCPSG CRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSANNRDNTY NRVSEDLRSRIEVL--KRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCS RALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKP------VPDL-V-PGNF KSQ----LQKVPPEWKALTDMPQMRMELERPGGNE-ITRGGSTSYGTGSETESPRNP--- --SSAGSWNSGSSGPGSTGNRN-------------------------------------- --------PGSSGTGGTATWK-----PGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGS TGTWNP-------------GSSERGSAGHWTSE-----SSVS--------GSTGQW---H SESGSFRPDSPGS-GNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKEL---- ------RTGKEKVTSG---STT--TTRRSCSKTVTKTVI-GPDGHKEVTKEVVTSEDGSD CPEAMDLG-----------------TLSGIGT-LDGFRHRHPDEAAFFDTA------STG K--TFPGFFSPMLGEF-----------VSETESRG-SESGIFTNTKESSSH-----HPGI AEF-----PSRGKSSSYSKQF-TS-STSYNRGDSTFES-----KSYKM------------ ADEAGSEADHE---GTHST-----KRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPG- -SSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDY LHLLTQRG-SV---LRVELEDWAGNEAYAEY-HFRVGSEAEGYALQVSSYEGTAGDALIE GSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYD PRNNSPYEIENGVVWVSFRGADYSLRAVRMKIRPLVTQ------ >sp|P02671-2|FIBA_HUMAN Isoform 2 of Fibrinogen alpha chain OS=Homo sapiens OX=9606 GN=FGA ----------------------------------------MFS------MRIVCLVLSVV GTAWTADSG---EGDFLAEGGGVRGPRVVER---HQSACK-DSDWPFCSDEDWNYKCPSG CRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSANNRDNTY NRVSEDLRSRIEVL--KRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCS RALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKP------VPDL-V-PGNF KSQ----LQKVPPEWKALTDMPQMRMELERPGGNE-ITRGGSTSYGTGSETESPRNP--- --SSAGSWNSGSSGPGSTGNRN-------------------------------------- --------PGSSGTGGTATWK-----PGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGS TGTWNP-------------GSSERGSAGHWTSE-----SSVS--------GSTGQW---H SESGSFRPDSPGS-GNARPNNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKEL---- ------RTGKEKVTSG---STT--TTRRSCSKTVTKTVI-GPDGHKEVTKEVVTSEDGSD CPEAMDLG-----------------TLSGIGT-LDGFRHRHPDEAAFFDTA------STG K--TFPGFFSPMLGEF-----------VSETESRG-SESGIFTNTKESSSH-----HPGI AEF-----PSRGKSSSYSKQF-TS-STSYNRGDSTFES-----KSYKM------------ ADEAGSEADHE---GTHST-----KRGHAKSRPVRG----IHTSPLGKPS---------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------LSP---------- >NP_001104518.1 fibrinogen alpha chain isoform 1 preproprotein [Mus musculus] ----------------------------------------MLS------LRVTCLILSVA STVWTTDTED--KGEFLSEGGGVRGPRVVER---HQSQCK-DSDWPFCSDDDWNHKCPSG CRMKGLIDEANQDFTNRINKLKNSLFDFQRNNKDSNSLTRNIMEYLRGDFANANNFDNTY GQVSEDLRRRIEIL--RRKVIEKAQQIQALQSNVRAQLIDMKRLEVDIDIKIRSCKGSCS RAVNREINLQDYEGHQKQLQQVIAKELLPTKDRQYLPALKMSP------VPDL-V-PGSF KSQ----LQEAPPEWKALTEMRQMRMELERPGKDG-GSRGDSPGDSRGDSRGD------- ---------FATRGPGSK-AEN-------------------------------------- --------PTNPGPGGSGYWR-----PGNSGSGSDGNRNPGTTGS-------------DG TGDW-------------------------------------------------------- -GTGSPRP-GSDS-GNFRPANPNWGVFSEFGDSSSPATRKEYHTGKAVTSKGDKEL---- ------LIGKEKVTSS---GTS--TTHRSCSKTITKTVT-GPDGRREVVKEVITSDDGSD CGDATELD--------------ISHSF--SGS-LDELSERHPDLSGFFDNHF-------- ------GLISPNFKEF-----------GSKTH----SDSDILTNIEDPSSH--------V PEF-----SSSSKTSTVKKQV----------------T-----KTYKM------------ ADEAGSEAHRE--GETRNT-----KRGRARARPTRDCDDVLQTQTSGAQNGIFSIKPPG- -SSKVFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNDY LHLLTLRG-SV---LRVELEDWAGKEAYAEY-HFRVGSEAEGYALQVSSYRGTAGDALVQ GSVEEGTEYTSHSNMQFSTFDRDADQWEENCAEVYGGGWWYNSCQAANLNGIYYPGGTYD PRNNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLVGQ------ >NP_001008724.1 fibrinogen alpha chain isoform 1 precursor [Rattus norvegicus] ----------------------------------------MLS------LRVACLILSLA STVWTADTGT--TSEFIEAGGDIRGPRIVER---QPSQCK-ETDWPFCSDEDWNHKCPSG CRMKGLIDEANQDFTNRINKLKNSLFDFQKNNKDSNSLTRNIMEYLRGDFANANNFDNTF GQVSEDLRRRIEIL--KRKVIEKAQQIQVLQKDVRDQLIDMKRLEVDIDIKIRSCKGSCS RSVSREINLKDYEGQQKQLEQVIAKELLPAKDRQYLPAIKMSP------VPDL-V-PGSF KSQ----LQEGPPEWKALTEMRQMRMELERPGKDG-ASRGDLPGDSRGDS---------- ----------ATRGPGSK-IEN-------------------------------------- --------PMTPGHGGSGYWR-----PGSSGSGSDGNWGSGTTGS-------------DD TGTW-------------------------------------------------------- -GAGSSRP-SSGS-GNLKPSNPDWGEFSEFGGSSSPATRKEYHTGKLVTSKGDKEL---- ------LIGNEKVTST---GTS--TTRRSCSKTITKTVL-GNDGHREVVKEVVTSDDGSD CGDGMDLG--------------LTHSF--SGR-LDELSRMHPELGSFYDSRF-------- ------GSLTSNFKEF-----------GSKT-----SDSDIFTDIENPSSH--------V PEF-----SSSSKTSTVRKQV----------------T-----KSYKM------------ ADEAASEAHQE--GDTRTT-----KRGRA--RTMRDCDDVLQTHPSGAQNGIFSIKLPG- -SSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNDY LHLLTLRG-SV---LRVELEDWAGKEAYAEY-HFRVGSEAEGYALQVSSYQGTAGDALME GSVEEGTEYTSHSNMQFSTFDRDADQWEENCAEVYGGGWWYNSCQAANLNGIYYPGGTYD PRNNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLVGQ------ >NP_001258840.1 fibrinogen alpha chain isoform 1 precursor [Gallus gallus] ----------------------------------------MIP------VTILCVLLCL- NLAWAQDG----KTTFEKEGGGGRGPRILENM--HESSCKYEKNWPICVDDDWGTKCPSG CRMQGIIDDTDQNYSQRIDNIRQQLADSQNKYKTSNRVIVETINILKPGLEGAQQLDENY GHVSTELRRRIVTL--KQRVATQVNRIKALQNSIQEQVVEMKRLEVDIDIKIRACKGSCA RSFDYQVDKEGYDNIQKHLTQASSIDMHPDFQTTTLSTLKMRP------LKDSNV-PEHF KLK----PSPEMQAMSAFNNIKQMQVVLERPETD-----------HV------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AEAR-GDSSP----------------------SHTGKLITSSHRRES---- -----------PSLVD---KTSSASSVHRCTRTVTKKVISGPDGPREEIVEKMVSSDGSD CSHLQG-----------GREG-STYHFSGTGD-FHKLDRLLPDLESFFTHD----SVSTS SRHSIGSS---TSSHV-TGAGSSHLGTG---------GKDKFTDLGEEEEDDFGG--LQP SGF-------AAGSASHSKTVLTSSSSSFNKGGSTFET-----KSLKTRETSEQLGGVQH DQSAEDTPDFK-ARSFRPA-----AMSTRRSYNGKDCDDIRQKHTSGAKSGIFKIKPEG- -SNKVLSVYCDQETTLGGWLLIQQRMDGSVNFNRTWQDYRRGFGSVDGKGQGELWLGNEN IHLLTQND-TL---LRVELEDWDGNAAYAEY-IVQVGTEAEGYALTVSSYEGTAGDALVA GWLEEGSEYTSHAQMQFSTFDRDQDHWEESCAEVYGGGWWYNSCQAANLNGIYYPGGHYD PRYNVPYEIENGVVWIPFRASDYSLKVVRMKIRPLETL------ >XP_001136067.1 fibrinogen alpha chain [Pan troglodytes] ----------------------------------------MFS------MRIVCLVLSVV GTAWTADSG---EGDFLAEGGGVRGPRVVER---HQSACK-DSDWPFCSDEDWNYKCPSG CRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSANNRDNTY NRVSEDLRSRIEVL--KRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCS RALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKP------VPDL-V-PGNF KSQ----LQKAPPEWKALTDMPQMRMELERPGRNE-ITRGDSTSYGTGSETESPRNP--- --SSAGSWNPGSSGPGSSGNRN-------------------------------------- --------PGSSGTGGTATWK-----PGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGS TGTWNP-------------GSSEHGSAGHWTSE-----SSVS--------GSTGQW---H SESGSFRPDSSGS-GNARPTNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKEL---- ------TTGKEKVTSG---STT--TTRRSCSKTVTKTFI-GHDGHKEVTKEVVTSEDGSD CPEAIDLG-----------------TLSGIGT-LDEFRHRHPDEATFFDTA------STG K--TFSGLFSPMFREF-----------VSETESRG-SESGIFTNTKESSSH-----PPGI AEF-----PSRGKTSSHSKQF-TS-GTSYSRGGSTFES-----KSYKM------------ ADEAGSEADHE---GTHST-----KRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPG- -SSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDY LHLLTQRG-SV---LRVELEDWAGNEAYAEY-HFWVGSEAEGYALQVSSYEGTAGDALIE GSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYD PRNNSPYEIENGVVWVSFRGADYSLRAVRMKIRPLVTQ------ >XP_038544611.1 fibrinogen alpha chain isoform X1 [Canis lupus familiaris] ----------------------------------------MFS------AKILCLVLSVV GTVWTTNSK---EGEFIAEGGGVRGPRIVER---QQSACK-ETDWPFCSDEDWNYKCPSG CRMKGLIDEVNQDFTNRINKLKNSLFDYQKNNKDSSSLTTNIMELVRGDFATANNNDNTY SQVSEDLRSKIEIL--RRKVLEQVQHIHLLQKNVRDQLVDMKRLEVDIDIKIRSCQGSCS RALERRTDLKYYEDQQKQLEQVIAKDLLPPKDRQYLPLLKTSP------APNM-L-PGDY KSQ----LQEAPLEWKALMEMKQMKMTLERLDRDG-NARGDTPSHGTGSVPESPRNPGSS TPGSAGTWNPGSTGPGSAGPWSSGSTRPGSTGPGSAGTWSTRPGSTGPGSAGTWST---- -------RPGSTGPGSAGTWSSGSTGPGSTGPGSTGTWSSGSTGP--------GNTGPGS TGTWSSG-----STG---PGNTGPGSTGTWSSG-----STGPGNTGP---GSTGTWSSGS SDSESFRPGSVGH-GNTRPTNPEWGTFEEVSGSVTPGLKNEFHTGKLVTSKGEKEL---- ------LIGNEKVTSG---STT--TTRHACSKTVTKTVI-GPDGRKEVTKEVVNSEDGSD CGD-------------------LSHTF--AGS-LDDLHARHPDLERFFGTS------IVK ---TPPGILLPSRKEF-----------EHKTHIMG-SDSDIFTNI-------------GT PEF-----PSSGKTSSHSKQFVTS-STTYNRGDSAFES-----KSYKG------------ AGEAGTEAEREIFRGEYSI-----KRGHAKARPARDCDDVLQTHPSGAQSGIFNIKLPG- -SSKLFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLDDKGEGEFWLGNEH LHLLTLRA-SV---LRVELEDWAGNQAYAEY-HLRVGSEAEGYALQVSSYEGTAGDALVE GSAEEGTEYTSHAGMQFSTYDRDADQWEENCAEVYGGGWWYNSCQAANLNGIYYPGGSYD PRNNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLETR------ >XP_005217494.2 fibrinogen alpha chain isoform X1 [Bos taurus] ----------------------------------------MFS------VRDLCLVLSLV GAIKTEDGSDPPSGDFLTEGGGVRGPRLVER---QQSACK-ETGWPFCSDEDWNTKCPSG CRMKGLIDEVDQDFTSRINKLRDSLFNYQKNSKDSNTLTKNIVELMRGDFAKANNNDNTF KQISEDLRSRIEIL--RRKVIEQVQRINVLQKNVRDQLVDMKRLEVDIDIKIRSCKGSCS RALEHKVDLEDYKNQQKQLEQVIAINLLPSRDIQYLPLIKMST------ITGP-V-PREF KSQ----LQEAPLEWKALLEMQQTKMVLETFGGDG-HARGDSVSQGTGLAPGSPRKPGT- --SSIGNVNPGSYGPGSSGTWN-----PGRPEPGSA---------------GTWN----- --------PGRPEPGSAGTWN-----PGRPEPGSAGTWNPGRPEPGSAGTWNPGRPEPGS AGTW----------------------------------------------------NTGS SGSSSFRPDSSGH-GNIRPSSPDWGTFRE-EGSVSSGTKQEFHTGKLVTTKGDKEL---- ------LIDNEKVTSG---HTT--TTRRSCSKVITKTVT-NADGRTETTKEVVKSEDGSD CGDA-DFD--------------WHHTFPSRGN-LDDFFHRDKD----------------- ------DFFTRSSHEF-----------DGRTG----LAPEF----------------AAL GES----GSSSSKTSTHSKQFVSS-STTVNRGGSAIES-----KHFKM------------ EDEAESLEDLG-FKGAHGT-----QKGHTKARPARDCYDVLQTRPSGAQSGIFSIKLPA- -SSKIFSVYCDQETGLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEY LHLLTLRG-SI---LRVELEDWAGKGAYAEY-HLRVGSEAEDYALEVSSYKGTAGDALIE GSVEEGTEYTSHTGMRFSTFDRDADKWEDNCAEVYGGGWWYNNCQAANLNGIYYPGGSYD PRDNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLVTQ------ >XP_002716943.1 PREDICTED: fibrinogen alpha chain [Oryctolagus cuniculus] ----------------------------------------MFS------MKILCLLLCAV GTVWTVDPG---ESTFIDEGATGRGPRVVDK---PPSSCK-EADWPFCADDDWNQKCPSG CRMKGLIDEMNQDFTDRMNKLRNSLFDYQKNNKDSSSVVTNIMEYLRGNLATANNYDTTY NQVSEELRRRIEVL--QRKVIEKVQHIKLLQNNVRAQLIDMKRLEVDIDIKIRSCQGSCN RVLSHEVNLKDYEDQQKQLEQVIAKDLLPPPDRQYLPTIKMTP------VADL-V-PGEY KSQ----LQKAHPEWKALTEMKQMKVVVEKSGRGE-TARGDSASFGTGSETGSHRNPGH- ------------------------------------------------------------ --------------GSEGPWP-----TGSSGS-STSHWTSGSFGS-------------GN VGTRNP----------------------------------------------------GI SGHGSIRPDSSGH-GSTRPTHPDWGTFEEISGNVSPGTKKEFHTEKLVTSKGDKEM---- ------LISNERATSGSSSSTS--TVRRSCSKTITKTVT-GPDGHKQVVKEVVHSEDGSE CPEVPDLD--------------SMHSFMSRGS-LDDFSFRHPGEASFFDTS------STG KASTFPGLLSTSFKEF-----------GSKSQSMG-SESDFFTDAEGAGSH--------H TSF-----PSSGKTTTHRKQIVTS-HTAFNRGGSTVES-----KSYKM------------ ADEAGGEADQE-LRHTHTS-----RRTHAKVRPSRDCDDVLQTHPSGAQSGIFNIKLPG- -SSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNDQ LHLLTLRA-SV---LRVELEDWDGRGAYAEY-HFRVGSEAEGYALQVSSYEGTAGDALIE GSVEEGAEYTSHNSMQFSTFDRDADHWEENCAEVYGGGWWYNNCQAANLNGIYYPGGPYD PRNNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLRTP------ >XP_002815279.3 fibrinogen alpha chain isoform X1 [Pongo abelii] ----------------------------------------MFS------VRILFLVLSVV GTAWTADSG---EGDFLAEGGGVRGPRVVER---HQSACK-DSDWPFCSDEDWNYKCPSG CRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSNSLTTNIMEILRGDFSSANNRDNTY NRVSEDLRSRIEVL--KRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCS RALAHEVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKP------VPDL-V-PGNF KSQ----LNKAPPEWRALTDMPQMRMELERPGRNE-VTRGDSTSYGTGSEMESPRNP--- --SSAGSWSPGSSGPGSTGNRN-----PGSSGTGSTGTWN--PGSSGTGSTGTWKPGSSG TGSTGTWKPGSSGTGSTGTWK-----PGSSGSGSTGAWNSGSSGTVSTGNQNPGSPRPGS TGTWNP-------------SSSGHGSAGHWSSE-----SSVS--------GSTGHW---H SESGSFRPDSSGS-GNMRPTNPDWGTFEEVSGNVSPGTKREYHTDKLVTSKGDEEL---- ------TTGKEKVTSG---STT--TTRRSCSKTVTKTVI-GPDGHKEVTKEVVTSEDGSD CPEGIDLG-----------------TLSGIGT-LDEFRHRHPDEAAFFETA------STG K--TFPGFFSPMFREF-----------VSETESMG-SESGIFTNTKESSSR-----HPGI AEF-----PSSGKTSSHSKQF-IT-STSYNREGSTFES-----KSYKM------------ ADEAGSEADHE---GTHST-----KRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPG- -SSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDY LHLLTQRG-SV---LRVELEDWAGNKAYAEY-HFRVGSEAEGYALQVSSYEGTAGDALIE GSVEEGTEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYLGGSYD PRNNSPYEIENGVVWVSFRGADYSLRAVRMKIRPPATQ------ >XP_003205398.1 fibrinogen alpha chain [Meleagris gallopavo] ----------------------------------------MIP------LRILCVLLCL- NLAWAQDG----ETTFEKEGAAGRGPRIVEHM--HQSSCKYEKNWPMCVDDDWGIKCPSG CRMQGIIDDTNQDNSHRIEKIRQQLADSQNNYKTSNRVIVETINILKPGLEGAQQLDENY GHVSAELRRRIVTL--KQRVANQVNRIKALQNSIQEQVVEMKRLEVDIDIKIRACKGSCA RSFDYQVDKEGYDNIQKQLTQASSIDMHPDFQATTLSTLKMRP------LKDSNV-PEHF KLK----PPPEMQALNVFNNIKQMQVVLERPETDS-RPSQGETFYHV------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------AEAR-GDSSP----------------------PHTSKLVTSAHGRET---- -----------PSLVD---KT---SSVHRCTRIVTKKVISSPDGPREEIVEKMVSSDGSD CSHLQG-----------GREG-STYHFSGTGD-FHKLDRFQPDLESFFTHD----S-ATG SRHSVSSSTTTTSSRV-TGAGSSHLGTG---------GKDKFTDLGEEEEDDFGG--LQP SGF-------AAGSASHSRTVVTSSSSSFNKGGSTFET-----KSLKTREISERLGGVQH DQSAEDTPDFQ-ARSFRQA-----AMSTRRDYSGKDCDDIRQKHTFGAKSGIFKIKPEG- -SSKVLSVYCDQETTLGGWLLIQQRMDGSVNFNRTWQDYKRGFGSVDGKGRGELWLGNEN IHLLTQND-TL---LRVELEDWDGNAAYAEY-IMQVGTEAEGYALAVSSYEGTAGDALVA GWLEEGSEYTSHAQMQFSTFDRDQDRWEESCAEVYGGGWWYNSCQAANLNGIYYPGGHYD PRYNVPYEIENGVVWIPFRASDYSLKVVRMKIRPLDTL------ >XP_020957142.1 fibrinogen alpha chain isoform X1 [Sus scrofa] MG-W------------DVAAETILSSSRSAPPERAPPLAKMFS------VRLFCLVLTVV GTVQMAEVQD--KGEFLAEGGGVRGPRLTER---HQSACK-ESDWPFCSDEDWNIKCPSG CRMKGLIDEVNQDFTNRINKLKNSLFDYQKNNKDSSTLSRNIIELLRGDFSNANNNDNIY SQVSEELRSRIEIL--KRKVLEKVQHIHLLQKNVRDQLIEMKRLEVDIDIKIRSCKGSCS RALEHKVDLKDYENQQKQLDQVIAINLLPSRDRQYLPLIKISP------LPDI-T-PADF KTQ----ARETPPEWKALLETRQVKMVLERVGGDE-RTRGGSISHGPGSVPGT------- --GSPGGLKPGSYGPGGPGTWK-----PGRPEPGST---------------GTWD----- --------SGHPDPGSAGTWK-----PGRPEPGSTGTWDSGHPDPGSAGTWKPGRPEPGS TGTWDSGRPDPGSAGTWKPGRPESGSTGTWHSEHLEHGSSSTWHSGQHEHGSVGSWKPGS SGSGSLRPDSSGP-GDTTPSNPDWGTFKEVSGSVSPGTKSEVHTSKLVTSKGDKDI---- ------VIGKEKVTSG---HTS--TTHRSCSKTITKTVT-KADGRTETIKEVINSEDGSD CGGT-DVE--------------FAHMLPGKGS-LDEFFHRHRD-----ETS------LSR D--PFPDFFSPVLKEF-----------DGKTHPGG-PGSDL------AGFF-----HPDG PEY-----SSSSKISSHSKQTITK---TINREGGAVES-----KSYKM------------ EDEADSEEGLD-LKGGHVI-----KRVYTRTRPARDCGDALQTHPSGAQSGIFNIELPG- -SSKIFSVYCDQETDLGGWLLIQQRTDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEY LHLLTLRG-SV---LRVELEDWAGKGAYAEY-HLRVGSEAEGYALQVSSYKGTAGDALIE GSPEEGSEYTSHAGMQFSTFDRDADKWEENCAEVYGGGWWYNNCQAANLNGIYYTGGSYD PRDNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLVTP------ >XP_003822627.2 fibrinogen alpha chain [Pan paniscus] ----------------------------------------MFS------MRIVCLVLSVV GTAWTADSG---EGDFLAEGGGVRGPRVVER---HQSACK-DSDWPFCSDEDWNYKCPSG CRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSANNRDNTY NRVSEDLRSRIEVL--KRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCS RALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKP------VPDL-V-PGNF KSQ----LQKAPPEWKALTDMPQMRMELERPGRNE-ITRGDSTSYGTGSETESPRNP--- --SSAGSWNPGSSGPGSSGNRN-------------------------------------- --------PGSSGTGGTATWK-----PGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGS TGTWNP-------------GSSEHGSAGHWTSE-----SSVS--------GSTGQW---H SESGSFRPDSSGS-GNGRPTNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKEL---- ------TTGKEKVTSG---STT--TTRRSCSKTVTKTVI-GHDGHKEVTKEVVTSEDGSD CPEAIDLG-----------------TLSGIGT-LDEFRHRHPDEAAFFDTA------STG K--TFSGLFSPIFREF-----------VSETESRG-SESGIFTNTKESSSH-----HPGI AEF-----PSRGKTSSHSKQF-TS-GTSYSRGGSTFES-----KSYKM------------ ADEAGSEADHE---GTHST-----KRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPG- -SSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDY LHLLTQRG-SV---LRVELEDWAGNEAYAEY-HFRVGSEAEGYALQVSSYEGTAGDALIE GSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYD PRNNSPYEIENGVVWVSFRGADYSLRAVRMKIRPLVTQ------ >XP_019684378.1 fibrinogen alpha chain [Felis catus] ----------------------------------------MFS------LKIFCLALSVV GTVWTGDVQ---EGEFIAEGGGVRGPRIVEG---HHSVCK-ETDWPFCSDEDWNYKCPSG CRMKGLIDEVNQDFTNRINKLKNSLFDYQKNNKDSSLLTGNVMELVRGDFATGNNNDNTF SQVSEDLRSRIEIL--KRKVLEQVQHIQLLQKNVRDQLIDMKRLEVDIDIKIRSCQGSCS RALERRTDLKYYEDQQKQLEQVIAKDLLPSRDTQYLPLLKMRT------APDM-I-PGEY KHQ----LQKAPAEWKALMETQQMKITLERSGTDG-NAPGDSASHGTGSVPESPRNPGSS TPGSSGTWNPGSSGPGSSGAWN-----PGSTGPGSSGAWN--PGSSGPGSSGAWN----- --------PGSSTPGSSGAWNPGSSGPGSSGPGSSGAWNPGSSGPGSSGAWNPGSSGPGS GSTWNA-------------GSSGVSSAGTWNTE-----SASSWSTGT---GSGGSWSSGT PQPGSFRPDSLGH-GDTRPTKQEWGTVEEVSGSVSPGTKKEYHTGKLITSKGDKEL---- ------LIGNEKVTSG---STT--TTHRSCSKTVTKTVI-GPDGRKEVIKEVVNSEDGSD CD--------------------LSHAF--SGS-LGDLHSRHPDLASFFESA------STG S--KFSSVLTPTLREF-----------ES----MG-SESDIFTHL-------------GE HEL-----PSSGKTSTHSKQLVTT-SKTYNRGDSTFES-----KSFKV------------ AGEAGSEAEHEVLRGAYTT-----KRGHARARPARDCDDVLQTHPAGAQSGIFNIKLPG- -SSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLDDKGEGEFWLGNEY LHLLTLRG-SV---LRVELEDWAGNLAYAEY-HLRVGSEAEGYPLQVSSYQGTAGDALIE GSVEEGTEYTSHAGMQFSTYDRDADLWEENCAEVYGGGWWYNSCQAANLNGIYYPGGSYD PRNNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLVTHSEQK-- >XP_004017232.4 fibrinogen alpha chain [Ovis aries] ----------------------------------------MFS------VRDLCLVLSLV GAIQTADDSDPVGGEFLAEGGGVRGPRLVEK---QQSTCK-ETGWPFCADEDWGEKCPSG CRMKGLIDEVNQDFTGRINKLRDSLFNYQKTNKDSNTLTKNIVEILRGDFAKANNNDNTF NQVSEDLRSRIEIL--RRKVIEQAQHINLLQKNVKNQLVDMKRLEVDIDIKIRSCKGSCS RALEHKVDLEDYKNQQKQLEQVIAINLLPSRDTQYLSLIKMSA------VTGP-V-PREL KSQ----LREAPPEWKALLEMQQMKMVLENFGGDG-HARGDSVSHRTGLAPESPRKPGT- --GSIGNVNPGSYGPGSSGTWS-----PGH------------------------------ -----------PEPGSAGTWN-----TGRPEPGSAGTWNTGRPEPGSAGTWNTGRPEPGS AGTWNI-------------GSPEP--------------------------GSVGIRNTGS SGSSSFRPDSSGHGGNIRPSSPDWGTFRE-EGSVSSGTKKEFHTGKLVSAKGEKEL---- ------LIGNEKVSSG---HAT--TTRRSCSKVITKTVT-NAEGHTETTKEVVKSEDGSD CGDA-DFD--------------WDHTFSTRGN-LEDFFHRNSD----------------- ------GFFTHKLHEF-----------DGKTR----LESDV----------------PDL REI----GSSGSKTSAHSKQFLSS-STTISRGGSALES-----KNFKM------------ ADEAESIEDLG-IKGAHAT-----KTGHAKARPARDCYDVLQTHPSGAQSGIFSIKLPG- -SSKIFSVYCDQETGLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEY LHLLTLRG-SI---LRVELEDWAGKGAYAEY-HLRVGSEAEDYALEVSSYKGTAGDALIE GSVEEGTEYTSHTGMRFSTFDRDADKWEDNCAEVYGGGWWYNNCQAANLNGIYYPGGSYD PRDNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLVTQ------ >XP_018880884.1 fibrinogen alpha chain [Gorilla gorilla gorilla] ----------------------------------------MFS------MRIVCLVLSVV GTAWTADSG---EGDFLAEGGGVRGPRVVER---HQSACK-DSDWPFCSDEDWNYKCPSG CRMKGLIDEVNQDFTNRINKLKNSLLEYQKSNKDSHSLTTNIMEILRGDFSSANNRDNTY NRVSEDLRSRIEVL--KRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCS RALAREVDLKDYEDQRKQLEQVIAKDLLPSRDRQHLPLIKMKP------VPDL-V-PGNF KSQ----LQKAPPEWKALTDMPQMRMELERPGRNE-ITRGDSTSYGTGSETESPRNP--- --SSAGSWNPGSSGPGSTGNRN-------------------------------------- --------PGSSGTGGTATWK-----PGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGS TGIWNP-------------GSSERESAGHWTSE-----SSVS--------GSTGQW---H SESGSFRPDSSGS-GNARPTNPDWGTFEEVSGNVSPGTRREYHTEKLVTSKGDKEL---- ------TTGKEKVTSG---STT--TTRRSCSKTVTKTVI-GPAGHKEVTKEVVTSEDGSD CPEAMDLG-----------------TLSGVGT-LDEFRHRHPDEAAFFDTA------STG K--TFPGFFSPMFGEF-----------VSETESRG-SESGIFTNTKESSSH-----HPGL AEF-----PSRGKTSSHSKQF-TS-STSYSRGGSTFES-----KSYKM------------ ADEAGSEADHE---ETHST-----KRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPG- -SSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDY LHLLTQRG-SV---LRVELEDWAGNEAYAEY-HFRVGSEAEGYALQVSSYEGTAGDALIE GSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYD PRNNSPYEIENGVVWVSFRGADYSLRAVRMKIRPLLTQ------ >XP_013227609.1 fibrinogen alpha chain [Columba livia] ----------------------------------------MIS------MKILCVLLCL- NLAWAQDG----ETTFEKEGAGVRGPRIVEHM--SQSTCQYEKNWPFCADDDWGIKCPSG CRMQGLIDETDKDYSQRIDKIKKLLAENQNNYKKSNRVIVETINVLKPNLDSAQEIDENY GHVSGELRRRIVTL--KQRVVTQVNRIKALQSSIQEQVAEMKRLEVDIDIKLRACKGSCA RSFDYQVDKESYDNIQKQLTQANSINLHPELQTTTLSTLKMRP------LKDSNV-PEHF KHK----PLPEMQALNIINNIRQMQAVLERSETDI-NPSRGDSLYHV------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------SESR-GDGH-----------------------SHTSKLVTPIHERET---- -----------LSLGG---KTS--STVRRCTKTTTKKIVTGPDGPREEVVEKMVSSDGLD CSFLQGAGN-------VGGEG-TTYHVGGTGD-LHKLEKLFPELDSFFSPD----SPSTA GRPFGGSSSISTSSHL-TGTGSSHLGTGVSTHSGTYEGKGKFTDLREDEEDDFGGLHLQP SGF-------PSGSASHSKTVVTSASSSFNKGGSTFET-----KSLKTREITEQLGGVQH DESAEDIPDFQ-ARSFRPS-----GVKQRTPNTGKDCDDIRQKHTSGAKSGIFKIKPAG- -SNKVLSVYCDQETTLGGWLLIQQRMDGSVNFNRTWQDYKRGFGSVDGRGRGEFWLGNEN IHLLTQND-TL---LRIELEDWDGNAVYAEY-IVQVGSEEEGYALAVSSYEGTAGDALIT GWLEEGSEYTSHAQMRFSTFDQDQDHWEESCAEVYGGGWWYNSCQAANLNGIYYLGGHYD PRYNVPYEIENGVVWLPFRASDYSLKIVRMKIRPIETL------ >XP_005691214.3 PREDICTED: fibrinogen alpha chain [Capra hircus] ----------------------------------------MFS------VRDLCLVLSLV GAIQTADDSDPVGGEFLAEGGGVRGPRLVEK---QQSTCK-ETGWPFCADEDWGEKCPSG CRMKGLIDEVNQDFTSRINKLRDSLFNYQKNNKDSNTLTKNIVEILRGDFAKANNNDNTF NQVSEDLRSRIEIL--RRKVIEQAQHINLLQKNVKNQLVDMKRLEVDIDIKIRSCKGSCS RALEHKVDLEDYKNQQKQLEQVIAINLLPSRDTQYLSLIKMSA------VTGP-V-PREL KSQ----LREAPPEWKALLEMQQMKMVLENFGGDG-HARGDSVSHRTGLAPESPRKPGT- --GSIGNVNPGSYGPGSSGTWS-----PGHPEPGSAGAWN--TGSPEPGSAGTWN----- --------TGRPEPGSAGTWN-----TGRPEPGSAGTWNTGRPEPGSAGTWNTGRPEPGS AGTWNT-------------GSPEP--------------------------GSVGIRNTGS SGSSSFRPDSSGHGGNIRPSSPDWGTFRE-EGSVSSGTKKEFHTGKLVSAKGEKEL---- ------LIGNEKVTSG---HAT--TTRRSCSKVITKTVT-NAEGHTETTKEVVKSEDGSD CGDA-DFD--------------WDHTFSTRGN-LEDFFHRNSD----------------- ------GFFTHKLHEF-----------DGKTR----LESDV----------------PDL REI----GSSGSKTSAHSKQFLSS-STTISRGGSALES-----KNFKM------------ ADEAESIEDLG-IKGAHAT-----KTGHAKARPARDCYDVLQTHPSGAQSGIFSIKLPG- -SSKIFSVYCDQETGLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEY LHLLTLRG-SV---LRVELEDWAGKGAYAEY-HLRVGSEAEDYALEVSAYKGTAGDALIE GSVEEGTEYTSHTGMRFSTFDRDADKWEDNCAEVYGGGWWYNNCQAANLNGIYYPGGSYD PRDNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLVTQ------ >XP_006034117.1 LOW QUALITY PROTEIN: fibrinogen alpha chain [Alligator sinensis] ----------------------------------------MLQ------MRILCILLCL- SIVWAVEE----GSTFEEEGGVARGPRLSER---AQASCKHEKSWPFCSDDQWGQKCPSG CRMQGLIDDTNSDFNHRLDKIRKLLDDNENKYKKSKIITTETFNSMKGTLVSGQESDSKY GQVIEDLRRRIVSL--KTKVIAQIERIYGLQNSIREQVLEMKRMEVDIDIKIRACKGSCV KSSDYHVDKESYDNIQRQLTQASSINLQSDLSSSIIRVLKIKP------MKDSTI-LPHF KAG----DPKDWPEWNFLNKMQQLELVLESPETGP-KFFPVDTSYSS------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------SVHK-GDGEP-----------------------QGSKFVHTTYGKET---- ----------RFGEGV---SSS--STHYTCTKTVTKKVVTGPDGPREEVVEKYTSSDGSD CSHLRGLGKEDI----SGGYN-VRVTTGGGGDGMSDLDKVF----SFFSTD----SESDG SRHSSSSIGGTSSGFINTGTGSER-GSGGSSHSRGVQGSDASGELREGEED------WHI SEL-----PYSKTQSGVSSETVVSSSTSFNKGGSTFET-----KSLKT----XRLDGFPH DESTEDGPDFK-ACSFKMD-----TFFSGPRTTGTDCEDIRQKHTSGAKSGIFRIKPTG- -SSKVLSVYCDQETTLGGWLLIQQRIDGSVNFNQTWQDYKKGFGSVDAKGKGELWLGNEN IHLLTQKD-TV---LRVELEDWAGNTVYAEY-NIHVGSESQGYVLSVSNYEGTAGDALIT GSVDEGSEYTSHANMKFSTFDRDSDQWEENCAEVHGGGWWYNNCQAANLNGMYYLGGQYD PRNNIPYEVENGVVWIPFRASDYSLKIVRMKIRPNKTL------ >XP_043340007.1 fibrinogen alpha chain [Cervus canadensis] ----------------------------------------MFS------MRDLCLVLSLV GAVQAADGSDPASSDFLAEGGGVRGPRLVER---QQSTCK-ETGWPFCADEDWGEKCPSG CRMKGLIDEVNQDFTSRINKLRDSLFNYQKNNKDSNTLTKNIVELLGGDFAKANNNDNTF NQVSEDLRSRIEIL--RRKVIEQVQYINLLQKNVRDQLVDMKRLEVDIDIKIRSCKGSCS RALEHKVDLEDYKDQQKKLEQVIAIDLLPSRDVQYLPLIKMSA------ITGP-V-SREF KKQ----LQEVPSEWKALLEMQQTKMVLETFGGDG-HARGDSVSHGTGLAPERPRRPGT- --SSIGNVNPGSYGPGGS---------------------------------GTWN----- --------TGRPEPGSAGTWN-----TGRPEPGSAGTWNTGRPEPGSAGTWNTGRPEPGS AGTW----------------------------------------------------NTGS SGSSSFRPDSSGH-GNTRPSSPDWGTFRE-EGSVSSGTKKEFHTGKLVTTKGEKEL---- ------LIGNEGVSSG---HTT--TTRRSCSKVITKTVT-NADGRTETTKEVVKSEDGSD CGDA-DLD--------------WHRTLSVRGN-LDDFFSRNND----------------- ------GFLTHKLREF-----------DGKTG----LESGV----------------PAL EEF----GSSSGKTSTQSKQFVSS-STTINRGGSAIES-----KSFKM------------ ADEAESVEDLG-LKGAHAT-----QKGHAKARPARDCYDVLQTHPSGAQSGIFSIKLPG- -SSKIFSVYCDQETGLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEY LHLLTLRG-SI---LRVELEDWAGKGAYAEY-HLRVGSEAEGYALEVSSYKGTAGDALIE GSVEEGTEYTSHTGMRFSTFDRDADKWEDNCAEVYGGGWWYNNCQAANLNGIYYPGGSYD PRDNSPYEIENGVVWVPFRGADYSLRAARMKIRPLGHNRLTGWE >XP_043758605.1 fibrinogen alpha chain [Cervus elaphus] ----------------------------------------MFS------MRDLCLVLSLV GAVQAADGSDPASSDFLAEGGGVRGPRLVER---QQSTCK-ETGWPFCADEDWGEKCPSG CRMKGLIDEVNQDFTSRINKLRDSLFNYQKNNKDSNTLTKNIVELLGGDFAKANNNDNTF NQVSEDLRSRIEIL--RRKVIEQVQYINLLQKNVRDQLVDMKRLEVDIDIKIRSCKGSCS RALEHKVDLEDYKDQQKKLEQVIAIDLLPSRDVQYLPLIKMSA------ITGP-V-SREF KKQ----LQEVPSEWKALLEMQQTKMVLETFGGDG-HARGDSVSHGTGLAPERPRRPGT- --SSIGNVNPGSYGPGGSGTWN-----TGRPEPGSA---------------GTWN----- --------TGRPEPGSAGTWN-----TGRPEPGSAGTWNTGRPEPGSAGTWNTGRPEPGS AGTW----------------------------------------------------NTGS SGSSSFRPDSSGH-GNTRPSSPDWGTFRE-EGSVSSGTKKEFHTGKLVTTKGEKEL---- ------LIGNEGVSSG---HTT--TTRRSCSKVITKTVT-NADGRTETTKEVVKSEDGSD CGDA-DLD--------------WHRTLSVRGN-LDDFFSRNND----------------- ------GFLTHKLREF-----------DGKTG----LESGV----------------PAL EEF----GSSSGKTSTQSKQFVSS-STTINRGGSAIES-----KSFKM------------ ADEAESVEDLG-LKGAHAT-----QKGHAKARPARDCYDVLQTHPSGAQSGIFSIKLPG- -SSKIFSVYCDQETGLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEY LHLLTLRG-SI---LRVELEDWAGKGAYAEY-HLRVGSEAEGYALEVSSYKGTAGDALIE GSVEEGTEYTSHTGMRFSTFDRDADKWEDNCAEVYGGGWWYNNCQAANLNGIYYPGGSYD PRDNSPYEIENGVVWVPFRGADYSLRAARMKIRPLGHNRLTGWE >KAB0370205.1 hypothetical protein FD755_018167 [Muntiacus reevesi] ----------------------------------------MQETQ---EMQVQCL----- ----AADGSDPASGEFLTEGGGVRGPRLVER---QQSTCK-ETGWPFCADEDWGEKCPSG CRMKGLIDEVNQDFTSRINKLRDSLFNYQKNNKDSNTLTKNIVELLGGDFAKANNNDNTF NQVSEDLRSRIEIL--RRKVIEQVQHINLLQKNVRDQLVDMKRLEVDIDIKIRSCKGSCS RALEHKVDLEDYKDQQKTLEQVIAIDLLPSRDVQYLPLIKMSA------ATGP-V-SREF KKQ----LQEVPSEWKALLEMQQTKMVLETFGEDG-HARGDSVSHGTGLAPERPRRPGT- --SSTGNVNPGSYGSG-------------------------------------------- --------------GTRKCWH-----L-----------------XXXAGTWNTGRPEPGS AGTW----------------------------------------------------NTGS SGSSSFRPDSSGH-GNTRPSSPDWGTFRE-EGSVSSGTKKEFHTGKLVTTKGEKEL---- ------LIGNEGVSSG---HTT--TTRRSCSKVITKTVT-NADGRTETTKEVVKSEDGSD CGDA-DLD--------------WHRTLSVRGN-LDDFFSRNSD----------------- ------GFFTHKLHEF-----------DGKTG----LESGV----------------PAL EEF----GSSSGKTSTQSKQFVSS-STTINRGGSAIES-----KSFKM------------ ADEAESVEDLG-LKGAHAT-----QKGHAKARPARDCYDVLQTHPSGAQSGIFSIKLPG- -SSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEY LHLLTLRG-SI---LRVELEDWAGKGAYAEY-HLRVGSEAEGYALDVSSYNGTAGDALIE GSVEEGTEYTSHTGMQFSTFDRDADKWEDNCAEVYGGGWWYNNCQAANLNGIYYPGGSYD PRDNSPYEIENGVVWVPFRGADYSLRAARMKIRPLGHNRLTGGE >KAB0358664.1 hypothetical protein FD754_002820 [Muntiacus muntjak] ----------------------------------------MQETQ---EMQVQCL----- ----AADGSDPASGEFLTEGGGVRGPRLVER---QQSTCK-ETGWPFCADEDWGEKCPSG CRMKGLIDEVNQDFTSRINKLRDSLFNYQKNNKDSNTLTKNIVELLGGDFAKANNNDNTF NQVSEDLRSRIEIL--RRKVIEQVQHINLLQKNVRDQLVDMKRLEVDIDIKIRSCKGSCS RALEHKVDLEDYKDQQKTLEQVIAIDLLPSRDVQYLPLIKMSA------VTGP-V-SREF KKQ----LQEVPSEWKALLEMQQTKMVLETFGEDG-HARGDSVSHGTGLAPERPRRPGT- --SSTGNVNPGSYGSG-------------------------------------------- --------------GTRKCWH-----L-----------------XXXAGTWNTGRPEPGS AGTW----------------------------------------------------NTGS SGSSSFRPDSSGH-GNTRPSSPDWGTFRE-EGSVSSGTKKEFHTGKLVTTKGEKEL---- ------LIGNEGVSSG---HTT--TTRRSCSKVITKTVT-NADGRTETTKEVVKSEDGSD CGDA-DLD--------------WHRTLSMRGN-LDDFFSRNSD----------------- ------GFFTHKLHEF-----------DGKTG----LESGV----------------PAL EEF----GSSSGKTSTQSKQFVSS-STTINRGGSAIES-----KSFKM------------ ADEAESVEDLG-LKGAHAT-----QKGHAKARPARDCYDVLQTHPSGAQSGIFSIKLPG- -SSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEY LHLLTLRG-SI---LRVELEDWAGKGAYAEY-HLRVGSEAEGYALDVSSYNGTAGDALIE GSVEEGTEYTSHTGMQFSTFDRDADKWEDNCAEVYGGGWWYNNCQAANLNGIYYPGGSYD PRDNSPYEIENGVVWVPFRGADYSLRAARMKIRPLGHNRLTGWE >NP_001080329.1 fibrinogen alpha chain precursor [Xenopus laevis] ----------------------------------------MTQ-----WAALITLLLCFA GSVWSEG-----EGGIEAQGGSIRGPRIMESK--AESDCKQEKNWPICSDEDWGPKCPSG CRIQGLTDKTDKDFAKRIETIKQKFKDGEISYKSIDVQTKQTYENLKNNLIQAQQSDGKY NQASEDLRKKIEYL--KLKVSNQVERIKSLQRNIRDQVVEMKRLEVDIDIKIRACKGSCA KNTDYKVDLDSYNNIQKLLLQAETTDLSN--EMNSIRVLKMKP------IKDSPV-DSRY KTL--ALDKDQEAEFPIFKDINQYSFVLEGTKEEV-KGSSIGTSSVV------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------FP-S----GSGKDVD--------------------FQ-----GSKGTQSG---- -----TVKGGDQSTKV---ITE--SRTVSCTKTKKKRVIITPEGPKEEIIESY--SGGAE CEKLGKFSTGDT--FEAGSDGTRVIKISGSSS-LGDISKI-PSFEEFLSSSGKKTQTSQT SSSSSSSSSSTYSKGV---------------------THDAFSDLGEDEFDDFSHTGLDS PSFTPIQ---KEGSSTYTKTVVSSSSRGSTKDGTQFDI-----KSMKSGPVFDDFGPIQH DNSEEDRPDFQ-ARTVRKE-----T-KLVGDYTGKDCDDIRQKHSSGAKSGIFKIRPEG- -SSKVLTVYCDQDTQLGGWILIQQREDGSVNFNRTWQDYKNGFGSVDASGKGEVWLGNEN IHLLTQKD-TF---LRIELEDWSGEKAYAEY-NFQLGSESEGFILKVSQYEGTAGDALIE GSKEDG-EYTSHFNMKFSTYDRDSDKWEENCAEMYGGGWWYNNCQASNLNGIFYIGGQYD PRNSVPYEIENGVVWVPFKAADYSLKTVRMKIRPVETSG----- >XP_040187953.1 fibrinogen alpha chain-like [Rana temporaria] ----------------------------------------MLR------ATLVTVLLCLA STAWTAE-------DFEDVGATGRGPRILEQK--AAAGCKQEKNWPVCSDEDWGPKCPSG CRVQGLTTQTDKEFSKRIDAIKQKLKDGESNYKSIDVRTKETYELVKGNLVAAQQTDGAY NQVTENLRRKIEFL--KTKVTIQIDRIKLLQKNIRNQVVEMKRLEVDIDIKLRSCKGSCA KGVEYNVDYESYENIQKQLLQAESTDLRP--NVNAIPVLKMRP------IKDEAVTDSRY KTL-----AQQKEQYPIFSDIKQYSFVLEGKSKEV-SGQPVSTSSVS------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------GSTKEQP--------------------TQTFVIYGDKGTQPV---- -----KVSGGDK-TSV---TTE--SRVITCTKTITKKIVRGPDGPREEVFET---TSGDE CEKLEALKKEGK--GEFDADGTYTVKVTGSGS-AGGV-HI-PSWDDFLSGK----QVSGS SASSGSSTSKTQSSST---------------------KTQTSFTNGEDEFDDFSHVDLGA PSFQPIKTQSSSGSTTYSKTVVSS-SSGSTKDGTEWGT-----K-YKSGPVFEDLGPILE GNSEEDVPDFS-ARSVRPG-----V-KKTSSSTGSDCADILQKHSSGGKSGIFKIKPEG- -SQTELSVYCDQDTQIGGWLLIQQREDGSVNFNRTWQDYKHGFGSVDANGKGELWLGNKY IHMLSQNE-TI---LRVELEDWSGKQAFAEY-IFRLGSESEGFALHASSYEGLAGDALTE GSKEDS-ENTSHDKMKFSTYDRDNDKWEENCAEMYGGGWWYNNCQAANLNGIYYTGGQYD PRNNVPYEIENGVVWLSFKPDDYSLKTVKMKIRPVETA------ >NP_001181918.1 fibrinogen alpha chain precursor [Danio rerio] -------------------------------------------------MKFTHSLLCLF VAVSSALAE-------EDTVVNPRGARPIEHGFKAQDTCQ-TKEWPGCTDDDWGSKCPSG CRVQGLMDKADHDLLKKIEKIRRLLVEGQKLYRSADEVSKTTYTYLREKLTSNSGYDNRY MSLAEQLRQRITDI--KIKIDRQLRLLDALKSQVKDQVVVMQRLEVDIDIKLRTCKGSCA SYSEFSVDRESYVTLDKQMDNLNAMRVQSVETVSSLGIMKSRP------LKDVLV-PTIY KSG----TGKAEQKL-LFGDVGQMQLSLEAEGSTAESAATVSK----------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------FP-TSGT-GSTSQ----------------------------------------- ------------------------TSSKQCTKSVRKVITHTKDGPVEKV-EVS--SSGPG CDDLGKLGISDSEFLTAAKDG-KDLSRDGLKI-----------------------TVTGG DEKSLTSLSHSTS------------------------------DLGGFGGDFFKNLGTDN RKY-------ASSSSSTSTKTVSDGSKSYSK--TTLTS-----DPIFG----DDLGAFMR GDVEEDMPDIH-ARSVKSQ-----D-DRKAGFVGGDCVEIQQKHVNGGQSGMFKIKPAG- -SEEVVEVYCDQSTGLGGWTLVQQREDGSVNFNRTWKEYLNGFGQIDKQGKGEIWIGNKF LHLLTQKE-SL---LRVELQDWTGAEAYAEY-NIKVGSEAEGFPLTASDYDGDAGDALVR GHPNLGS-FLSHAGMKFSTFDRDSDKWEENCAEMYGGGWWYNNCQSANLNGIYYKGGQYD PATKVPYEIENGVVWLPFKPADYSLKVVRMKIRPV--------- >XP_030287455.1 fibrinogen alpha chain-like isoform X1 [Sparus aurata] -------------------------------------------------MQRLGLLVCFI -IGVTQS----------AVQVDPRGARPVEHGTRSEKCAS-EKEWPFCTTDEWGPKCPSG CRIEGLMNKYDHSLLKRIEKIRSLLDENTVKQRSTDSATKQTYDYLKDKLTTDAGHNNNY YDLAQNLRQRITDM--KIKIDRQLRILAALKDRVKDQVVEMQRLEVDVDIKLRSCKGSCQ GYAEFQVDHEDYVVLDKQINQLDSQSAQRIDSVKTLYVMKSRP------LKESNV-DSIY KSSDTTGAVAAQRREDVFTDVPMVQLLLGEEGSSS-SPATISKDQGT------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------S YSSPTFSSSSSSS-SSSSSSSSSSS---------------SSTPSKSITELGGSSH---L FGTDGGIQGLGGSATT---HMS--TQTISCTKSTRRTIVHTKDGPVEKVEEVY--EGGPE CQALGDSSK------------------GGMGA---------------------------- ---FFPTLTHT------------------------------------------------- ---------------------------GGAKGSLLGNTKTGFENPFGA--EGLDLGGFMK DNTEDDIPDFH-ARSVKSS-----RVERQADYVGKDCVEAYQNHLKGETNGLFNIRPGGT DSTQVVEVYCQQEGLMGGWMLVQQRENGALSFNRTWAEYRTGFGSVDAKGKGELWLGNQN LHLLTNQGETM---LKVELEDWEGGVAIAEY-IIRVGSEEEGYPLHVSGYTGDAGDALVM PKSDMAS-YLSHNGMKFSTFDKDNDRWEENCAEMYGGGWWYNNCQSANLNGMYYQ-GTYD PEKNKPYEIENGVVWVTYKTANYSLKTVRMFIRSSAF------- >XP_015801603.1 PREDICTED: fibrinogen alpha chain [Nothobranchius furzeri] -------------------------------------------------MKMMRLLVCLV CVAVTQV----------ASQVDPRGARPVEPATRSDKCST-QKEWPFCTDDDWLSKCPSG CRIQGLMDKADHELLKKIEKIRSLLNQNKAKHRSTDQVSKQTYDYLRDRLTTDSGNNNNY YDLAQSLRQRITDM--KIRIDNQMNTLAALKNRVKNQVTEMQRLEVDIDIKLRSCKGSCG GYSEYQVDKESYVNLDKQMRQLEAQSAQSVESVGTLYVMKTSS------LQTAAA-ETRF KSK----DVGGQKKDDVFSEVKTLQFVLEQEGSSS-SPATVSKEPGT------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------------S QLQGTPAP-LLPS-SSSSSSS-----------------------SKYITQLGGPGD---F PGGFGTFDNSGQDRVY---YGS--TKTSSCTKSIKRTVVLTKDGPVEKTEEVM--QGGPE CRGMTELTK------------------GGMSS---------------------------- ---LFPTLTHTSS----------------------------------------------- -------------SSSSSLTHTSSSSSGGAKGSLLGDSKLGFMDPFRD--DGFDLGAFMP DNAEDDVPDFH-ARSVKSA-----PVQRQDDFVGKDCVDAYQKHLKGETNGLFKIKPGGT DST-VVEVYCHQEGIMGGWLLVQQRASGSVSFNRTWAEYRDGFGSVDAEGNGEFWLGNQL LHLLTNQSETM---LKVELEDWEGGAATAEY-SVRVGSKEEGYPLHVSGFTGDAGDALLK ----------SHSGMKFSTFDKDDDKWERNCAEVYGGGWWYNSCQLANLNGVYYR-GSYD PKGSAPHQAENGVVWTTFKPATYSLKAVRMFVRPAEF------- >XP_011485484.2 fibrinogen alpha chain [Oryzias latipes] MGCWSRCSTLMRPDGRRLSGESQLWWRPSKDVTAA---AQMQSDTEERRMKQLVVLTCLL CVAFTQ-----------DTVIDPRGARPVEHGTRDEKCAT-QKEWPFCLDDDWGHKCPSG CRIQGLMDKYDHDLLKRIEYIRDQLNQHKGKYRSADQVSKQTHDYLREKLTVDAGHDNKY FELAQSLRQRITEI--KIRIDRQMKVMAALKGRIREQVTEMQRLEVDIDMKLRSCKGSCA TYHEYQVDQQSYVTLEKQVAQLDSQTPQNIEAAGTLYVMKSRP------LKDLQV-DSIY KSK----AVQGQQKQDLFSDIKTLKLVLEEEGSSS-SPATVSKEPGT------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----PFP-STSS-SSSSSSSSSSG---------------SSNPSKSITELGGRGDTDFF GGGLGGFGGFSQASTG---SVT--TKSVSCTTHMKKVVVQTKAGPVERYETVT--EGGPE CQGGADLTK------------------GGLTS---------------------------- ---LFPSLSHTSS----------------------------------------------- -------------SMS-----TKSGFSSGAKGGLLG-------NPFEG-DLGSDLGAFMT DNAEDDLPDFH-ARSLGST-----VVNRQADYVGKDCVEANQKHLKGETNGLFKIKPGGA DSTQVVEVYCQQEGVMGGWLLVQQRESGALSFNRSWADYRGGFGSVDAQGKGEFWLGNEN LHLLTSQGETI---LKVELEDWEGGKASAEY-TMRVGSEQEGFPLHVSGYTGDAGDSLAA PTSEKAS-EVTHDGMKFSAFDKDNDNWGENCAEAYGGGWWYNSCQAANLNGVYYK-GEYD PATNTPYKTENGVVWSSFKPVNYSLKTVRMLIRSAAF------- >XP_006275580.1 PREDICTED: LOW QUALITY PROTEIN: fibrinogen alpha chain [Alligator mississippiensis] M------------------------------------LLKMLQ------MRILCVLLYL- SIVWAVEE----GSTFEDEGGVARGPRLSER---AQASCKHEKSWPFCSDDQWGQKCPSG CRMQGLVDDTNSDFNHRLDKIRKLLDDNENKYKKSKIITTETFNSMKGTLVSGQESDSKY GQVIEDLRRRIVSL--KTKVIAQIERIYGLQNSIREQVLEMKRMEVDIDIKIRACKGSCA KSFDYHVDKESYDNIQRQLTQASSINLQSDLSSSIIRVLKIKP------MKDSTV-LPHF KAG----DPKDWPEWNFLNKMQQLELVLESPETGP-KFFPVDTSYSS------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------SVHK-GDGEP-----------------------QGSKFVHPTYGKET---- ----------HFGEGV---SSS--STHYTCTKTVTKKVVAGPDGPREEVVEKYTSSDGSD CSHLRGLGKEDI----SGGYN-VRVTAGGGGDGMSDLDKVF----SFFSTD----SESDG SRHSSSSIGGTSSGFINTGTGSER-GSGGSSHSRGVQGSDASGELREGEED------WHI SEL-----PYSKTQSGVSSETVVSSSTSFNKGGSTFET-----KSLKT----XRLDGFPH NESTEDGPDFK-SRSFKMD-----TFFSGPRTTGTDCEDIRQKHTSGAKSGIFRIKPTG- -SNKVLSVYCDQETTLGGWLLIQQRIDGSVNFNQTWQDYKKGFGSVDAKGKGELWLGNEN IHLLTQKD-TV---LRVELEDWAGNTVYAEY-NIHVGSESQGYVLSVSNYEGTAGDALIT GSVDEGSEYTSHANMKFSTFDRDSDQWEENCAEVHGGGWWYNNCQAANLNGMYYLGGQYD PRNNIPYEVENGVVWIPFRASDYSLKIVRMKIRPNETL------ >XP_020747240.1 fibrinogen alpha chain [Odocoileus virginianus texanus] ----------------------------------------MFS------VRDLCLVLSLV GAFQAADGSDPAGGEFLAEGGGVRGPRLVER---QQSTCK-ETGWPFCADEDWGEKCPSG CRMKGLIDEVNQDFTSRINKLRDSLFNYQKNNKDSNTLTKNIVELLGGDFAKANNNDNTF NQVSEDLRSRIEIL--RRKVIEQVQHINLLQKNVRDQLVDMKRLEVDIDIKIRSCKGSCS RALEHKVDLEDYKDQQKKLEQVIAIDLLPSRDVQYLPLIKMSP------VAGP-V-SREF KRQ----LQEVPQEWKALLEMQQTKMVLETFGGDG-HARGDSVSHGTGLAPERPRRPGT- --SSIGNVNPGSYGPGGS---------------------------------GTWN----- --------TGHPEPGSAGTWN-----TGRPEPGSAGTWNTGRPEPGSAGTWNTGRPEPGS AGTW----------------------------------------------------NTGS SGSSSFRPDSSGH-GNTRPSSPDWGTFRE-EGSVSSGTKKEFHTGKLVTTKGEKEL---- ------LIGNEGVASG---HTT--TTRRSCSKVITKTVT-NADGRTETTKEVVKSEDGSD CGDA-DLD--------------WHRTLSVRGN-LDDFFSRNSD----------------- ------GFFTHKLHEF-----------DGKTG----LESGV----------------PAL EEI----GSSSGKTSTQSKQYVSS-STTINRGGSTIES-----KSFKM------------ ADEAESVEDLG-LKGAHAA-----QKGHVKSRPARDCYDVLQTHPSGAQSGIFSIKLPG- -SSKIFSVYCDQETGLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEY LHLLTLGG-SI---LRVELEDWAGKGAYAEY-HLRVGSEAEGYALEVSSYKGTAGDALIE GSVEEGTEYTSHTGMRFSTFDRDADKWEDNCAEVYGGGWWYNNCQAANLNGIYYPGGSYD PRDNSPYEIENGVVWVPFRGADYSLRAARMKIRPLGHNRLTGWE >XP_031552222.1 angiopoietin-2-like [Actinia tenebrosa] ----------------------------------------MISP---------------- -------------------------PHLIVN----------------------------- --------------------------------------------------------ESQS ALFHYSIRGNPQPLFGWSKVGGSLDTTRSIVNSSRGI----------LEIK--------- -----HVTFSDSGIYQCNASSIJGKAL-----ATTRLVVNYRPR---VSLKKGPI----- ---------------------------YVKIGDNV-TLPTCHVMGHP-----KPR----- ------------------------------------------------------------ ------------------------------------------------------------ -VTW-------------------------------------------------------- ---------SRSI-GKLPSN---------------------------------------- ------------------------RTLTRDNELTLFNVVKDDSGTYVCTSDNFLGSDAAG C----------------------------------------------------------- ------VLVVVQLPVF---------------------------VVRPPNISYAIV----- --------GSSLTLNCSAKGDPEQ-VISWRRENGALPS-----GRYEI----TPNGSLVL RNIQASDDDIY-VCSATSAGVFDVQVKSTLNIFYHDCSEIYK--SGERRSGVYTIKPD-- -SERAFQVYCDMTTDGGGWTVFQRRQDGSVDFYRDWQQYKTGFGNLN----GEFWLGNDY IHRLTEKTPSV---LRVELEDWNRNKKYAKYGSFSVGDESDKYRLKVASYSGDAGDSLI- ----------SHHNNLFSTKDRDNDKHQSKCTTLFGGAWWYRACYDSNLNGKYF-GNKRD ---------EKGIAWEGFH-YDLSLKYSEMKIRPISF------- >XP_039268423.1 angiopoietin-related protein 2-like [Styela clava] ----------------------------------------MSR------IVVVTLFIALL ----------------------------------------------FCG----------- -HVRSQLTVVDPPIMQ----------------------------------IATGGDNNGK SNMKYDVKIRKYTV---------VRVPETPPSTTTEISTTTTTPPPDLDVN--------- -----HIEVQTRSTFEENLLEEDH------DCAFTFTLPNPRPSNQQVCVRDVRALMTSY PEE-------------------------RRSGDEE-ALNTLRNEISL------------- ------------------------------------------------------------ ------------------------------------------------------------ ---W-------------------------------------------------------- ---------QESM-GDLKTQIEE-----------------RLAVPSLEPVRNDVRLL--- -----------QKESR---NMN--FRISQLYMQLLHEIIRKRDDTIEYTS---------- ------------------------------------------------------------ ---VENSVMNVTIKYY---------------------------ELKEKHEALVTD----- --------HKALKQQSQSQQEQIK-ILQTKMEEMVHRM-----NRMAV-----DIQLMGI DDEKDEVNDTA-NSSLSES-----------RSSYTNCVDIQL--YASKESGIYILTLPS- -LSRKMKVWCDFEQDPGGWTVIQRRSEGKVNFYRNFASYQRGFGSLE----GEFWLGLEN IHHLTNQP-GVNYKLHIDMEDWSGRKTFVEYGSFKLEGQDEGYRLKVAHYSGTAGDSL-- ---------TWHNNMKFTTKNVDNDPFARNCANYQKGGWWYNTCAHSNLNGVYYMGGHYR SK------FQDGIYWSEWRGGSYSLKHVEMKIKPSE--------
BMGE Cleaned alignment of selected proteins >sp|P02671|FIBA_HUMAN Fibrinogen alpha chain OS=Homo sapiens OX=9606 GN=FGA PE=1 SV=2 MRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDWNYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSANNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRHLPLIKMKPPGNFKSVPPEWKALTDMPQMRMELERPGGNERGGSTYGTGSETESPRNPSSAGSWNSGSSGPGSTSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSPRPGSTGTWHSESGSFRPDSPGSGNARPNNPDWGTFEESGNVSPGTRREYHTEKLVTSKGDKELRTGKEKVTSGTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLG-TLSGIGTLDGFRHRHPDAFFDTAMLGEFVSETESESGIFTNTKESPSRGKSSSYSKQF-TSSTSYNRGDSTFESKSYKMADEAGSEADHESRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQRGLRVELEDWAGNEAYAEYHFRVGSEAEGYALQVSSYEGTAGDALIEGSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENGVVWVSFRGADYSLRAVRMKIRPLVTQ >sp|P02671-2|FIBA_HUMAN Isoform 2 of Fibrinogen alpha chain OS=Homo sapiens OX=9606 GN=FGA MRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDWNYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSANNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRHLPLIKMKPPGNFKSVPPEWKALTDMPQMRMELERPGGNERGGSTYGTGSETESPRNPSSAGSWNSGSSGPGSTSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSPRPGSTGTWHSESGSFRPDSPGSGNARPNNPDWGTFEESGNVSPGTRREYHTEKLVTSKGDKELRTGKEKVTSGTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEAMDLG-TLSGIGTLDGFRHRHPDAFFDTAMLGEFVSETESESGIFTNTKESPSRGKSSSYSKQF-TSSTSYNRGDSTFESKSYKMADEAGSEADHESRPVRG----IHTSPLGKPS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSP---- >NP_001104518.1 fibrinogen alpha chain isoform 1 preproprotein [Mus musculus] LRVTCLILSVASTVWTTDTEKGEFLSEGGGVRGPRVVERHQSQCKDSDWPFCSDDDWNHKCPSGCRMKGLIDEANQDFTNRINKLKNSLFDFQRNNKDSNSLTRNIMEYLRGDFANANNFDNTYGQVSEDLRRRIEILRRKVIEKAQQIQALQSNVRAQLIDMKRLEVDIDIKIRSCKGSCSRAVNREINLQDYEGHQKQLQQVIAKELLPTKDRYLPALKMSPPGSFKSAPPEWKALTEMRQMRMELERPGKDGRGDSPDSRGDSRGD-----------FATRGPGSKPGPGGSGYWRPGNSGSGSDGNRNPGTTGS-----DGTGDW--GTGSPRP-GSDSGNFRPANPNWGVFSEGDSSSPATRKEYHTGKAVTSKGDKELLIGKEKVTSSTTHRSCSKTITKTVTGPDGRREVVKEVITSDDGSDCGDATELDHSF--SGSLDELSERHPDGFFDNHNFKEFGSKTHSDSDILTNIEDPSSSSKTSTVKKQV---------------TKTYKMADEAGSEAHREARPTRDCDDVLQTQTSGAQNGIFSIKPPGSSKVFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNDYLHLLTLRGLRVELEDWAGKEAYAEYHFRVGSEAEGYALQVSSYRGTAGDALVQGSVEEGTEYTSHSNMQFSTFDRDADQWEENCAEVYGGGWWYNSCQAANLNGIYYPGGTYDPRNNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLVGQ >NP_001008724.1 fibrinogen alpha chain isoform 1 precursor [Rattus norvegicus] LRVACLILSLASTVWTADTGTSEFIEAGGDIRGPRIVERQPSQCKETDWPFCSDEDWNHKCPSGCRMKGLIDEANQDFTNRINKLKNSLFDFQKNNKDSNSLTRNIMEYLRGDFANANNFDNTFGQVSEDLRRRIEILKRKVIEKAQQIQVLQKDVRDQLIDMKRLEVDIDIKIRSCKGSCSRSVSREINLKDYEGQQKQLEQVIAKELLPAKDRYLPAIKMSPPGSFKSGPPEWKALTEMRQMRMELERPGKDGRGDLPDSRGDS---------------ATRGPGSKPGHGGSGYWRPGSSGSGSDGNWGSGTTGS-----DDTGTW--GAGSSRP-SSGSGNLKPSNPDWGEFSEGGSSSPATRKEYHTGKLVTSKGDKELLIGNEKVTSTTTRRSCSKTITKTVLGNDGHREVVKEVVTSDDGSDCGDGMDLGHSF--SGRLDELSRMHPESFYDSRNFKEFGSKT-SDSDIFTDIENPSSSSKTSTVRKQV---------------TKSYKMADEAASEAHQE-RTMRDCDDVLQTHPSGAQNGIFSIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNDYLHLLTLRGLRVELEDWAGKEAYAEYHFRVGSEAEGYALQVSSYQGTAGDALMEGSVEEGTEYTSHSNMQFSTFDRDADQWEENCAEVYGGGWWYNSCQAANLNGIYYPGGTYDPRNNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLVGQ >NP_001258840.1 fibrinogen alpha chain isoform 1 precursor [Gallus gallus] VTILCVLLCL-NLAWAQDG-KTTFEKEGGGGRGPRILENHESSCKEKNWPICVDDDWGTKCPSGCRMQGIIDDTDQNYSQRIDNIRQQLADSQNKYKTSNRVIVETINILKPGLEGAQQLDENYGHVSTELRRRIVTLKQRVATQVNRIKALQNSIQEQVVEMKRLEVDIDIKIRACKGSCARSFDYQVDKEGYDNIQKHLTQASSIDMHPDFQTTLSTLKMRPPEHFKLEMQAMSAFNNIKQMQVVLERPETD-------HV----------------------------------------------------------------------------AEARGDSSP---------------------SHTGKLITSSHRRES-----PSLVDSSVHRCTRTVTKKVIGPDGPREEIVEKMVSSDGSDCSHLQG--YHFSGTGDFHKLDRLLPDSFFTHDTSSHVG-----GKDKFTDLGEE--AAGSASHSKTVLTSSSSFNKGGSTFETKSLKTDQSAEDTPDFKSYNGKDCDDIRQKHTSGAKSGIFKIKPEGSNKVLSVYCDQETTLGGWLLIQQRMDGSVNFNRTWQDYRRGFGSVDGKGQGELWLGNENIHLLTQNDLRVELEDWDGNAAYAEYIVQVGTEAEGYALTVSSYEGTAGDALVAGWLEEGSEYTSHAQMQFSTFDRDQDHWEESCAEVYGGGWWYNSCQAANLNGIYYPGGHYDPRYNVPYEIENGVVWIPFRASDYSLKVVRMKIRPLETL >XP_001136067.1 fibrinogen alpha chain [Pan troglodytes] MRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDWNYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSANNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRHLPLIKMKPPGNFKSAPPEWKALTDMPQMRMELERPGRNERGDSTYGTGSETESPRNPSSAGSWNPGSSGPGSSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSPRPGSTGTWHSESGSFRPDSSGSGNARPTNPDWGTFEESGNVSPGTRREYHTEKLVTSKGDKELTTGKEKVTSGTTRRSCSKTVTKTFIGHDGHKEVTKEVVTSEDGSDCPEAIDLG-TLSGIGTLDEFRHRHPDTFFDTAMFREFVSETESESGIFTNTKESPSRGKTSSHSKQF-TSGTSYSRGGSTFESKSYKMADEAGSEADHESRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQRGLRVELEDWAGNEAYAEYHFWVGSEAEGYALQVSSYEGTAGDALIEGSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENGVVWVSFRGADYSLRAVRMKIRPLVTQ >XP_038544611.1 fibrinogen alpha chain isoform X1 [Canis lupus familiaris] AKILCLVLSVVGTVWTTNSKEGEFIAEGGGVRGPRIVERQQSACKETDWPFCSDEDWNYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFDYQKNNKDSSSLTTNIMELVRGDFATANNNDNTYSQVSEDLRSKIEILRRKVLEQVQHIHLLQKNVRDQLVDMKRLEVDIDIKIRSCQGSCSRALERRTDLKYYEDQQKQLEQVIAKDLLPPKDRYLPLLKTSPPGDYKSAPLEWKALMEMKQMKMTLERLDRDGRGDTPHGTGSVPESPRNPGSAGTWNPGSTGPGSATGPGSAGTWSPGSTGPGSTGTWSSGSTGPGNTGPGSTGTWSSDSESFRPGSVGHGNTRPTNPEWGTFEESGSVTPGLKNEFHTGKLVTSKGEKELLIGNEKVTSGTTRHACSKTVTKTVIGPDGRKEVTKEVVNSEDGSDCGD-----HTF--AGSLDDLHARHPDRFFGTSSRKEFEHKTHSDSDIFTNI---PSSGKTSSHSKQFVTSSTTYNRGDSAFESKSYKGAGEAGTEAEREARPARDCDDVLQTHPSGAQSGIFNIKLPGSSKLFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLDDKGEGEFWLGNEHLHLLTLRALRVELEDWAGNQAYAEYHLRVGSEAEGYALQVSSYEGTAGDALVEGSAEEGTEYTSHAGMQFSTYDRDADQWEENCAEVYGGGWWYNSCQAANLNGIYYPGGSYDPRNNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLETR >XP_005217494.2 fibrinogen alpha chain isoform X1 [Bos taurus] VRDLCLVLSLVGAIKTEDGSSGDFLTEGGGVRGPRLVERQQSACKETGWPFCSDEDWNTKCPSGCRMKGLIDEVDQDFTSRINKLRDSLFNYQKNSKDSNTLTKNIVELMRGDFAKANNNDNTFKQISEDLRSRIEILRRKVIEQVQRINVLQKNVRDQLVDMKRLEVDIDIKIRSCKGSCSRALEHKVDLEDYKNQQKQLEQVIAINLLPSRDIYLPLIKMSTPREFKSAPLEWKALLEMQQTKMVLETFGGDGRGDSVQGTGLAPGSPRKPSSIGNVNPGSYGPGSSPEPGSAGTWNPGRPEPGSAGTWNPGRPEPGRPEPGSAGTWSSGSSSFRPDSSGHGNIRPSSPDWGTFREEGSVSSGTKQEFHTGKLVTTKGDKELLIDNEKVTSGTTRRSCSKVITKTVTNADGRTETTKEVVKSEDGSDCGDA-DFDHTFPSRGNLDDFFHRDKD------SSHEFDGRTGLAPEF-------SSSSKTSTHSKQFVSSSTTVNRGGSAIESKHFKMEDEAESLEDLGARPARDCYDVLQTRPSGAQSGIFSIKLPASSKIFSVYCDQETGLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEYLHLLTLRGLRVELEDWAGKGAYAEYHLRVGSEAEDYALEVSSYKGTAGDALIEGSVEEGTEYTSHTGMRFSTFDRDADKWEDNCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRDNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLVTQ >XP_002716943.1 PREDICTED: fibrinogen alpha chain [Oryctolagus cuniculus] MKILCLLLCAVGTVWTVDPGESTFIDEGATGRGPRVVDKPPSSCKEADWPFCADDDWNQKCPSGCRMKGLIDEMNQDFTDRMNKLRNSLFDYQKNNKDSSSVVTNIMEYLRGNLATANNYDTTYNQVSEELRRRIEVLQRKVIEKVQHIKLLQNNVRAQLIDMKRLEVDIDIKIRSCQGSCNRVLSHEVNLKDYEDQQKQLEQVIAKDLLPPPDRYLPTIKMTPPGEYKSAHPEWKALTEMKQMKVVVEKSGRGERGDSAFGTGSETGSHRNP-------------------GSEGPWPTGSSGS-STSHWTSGSFGS-----GNVGTRISGHGSIRPDSSGHGSTRPTHPDWGTFEESGNVSPGTKKEFHTEKLVTSKGDKEMLISNERATSGTVRRSCSKTITKTVTGPDGHKQVVKEVVHSEDGSECPEVPDLDHSFMSRGSLDDFSFRHPGSFFDTSSFKEFGSKSQSESDFFTDAEGAPSSGKTTTHRKQIVTSHTAFNRGGSTVESKSYKMADEAGGEADQEVRPSRDCDDVLQTHPSGAQSGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNDQLHLLTLRALRVELEDWDGRGAYAEYHFRVGSEAEGYALQVSSYEGTAGDALIEGSVEEGAEYTSHNSMQFSTFDRDADHWEENCAEVYGGGWWYNNCQAANLNGIYYPGGPYDPRNNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLRTP >XP_002815279.3 fibrinogen alpha chain isoform X1 [Pongo abelii] VRILFLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDWNYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSNSLTTNIMEILRGDFSSANNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCSRALAHEVDLKDYEDQQKQLEQVIAKDLLPSRDRHLPLIKMKPPGNFKSAPPEWRALTDMPQMRMELERPGRNERGDSTYGTGSEMESPRNPSSAGSWSPGSSGPGSTSGTGSTGTWKPGSSGSGSTGAWNSGSSGTGSPRPGSTGTWHSESGSFRPDSSGSGNMRPTNPDWGTFEESGNVSPGTKREYHTDKLVTSKGDEELTTGKEKVTSGTTRRSCSKTVTKTVIGPDGHKEVTKEVVTSEDGSDCPEGIDLG-TLSGIGTLDEFRHRHPDAFFETAMFREFVSETESESGIFTNTKESPSSGKTSSHSKQF-ITSTSYNREGSTFESKSYKMADEAGSEADHESRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQRGLRVELEDWAGNKAYAEYHFRVGSEAEGYALQVSSYEGTAGDALIEGSVEEGTEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYLGGSYDPRNNSPYEIENGVVWVSFRGADYSLRAVRMKIRPPATQ >XP_003205398.1 fibrinogen alpha chain [Meleagris gallopavo] LRILCVLLCL-NLAWAQDG-ETTFEKEGAAGRGPRIVEHHQSSCKEKNWPMCVDDDWGIKCPSGCRMQGIIDDTNQDNSHRIEKIRQQLADSQNNYKTSNRVIVETINILKPGLEGAQQLDENYGHVSAELRRRIVTLKQRVANQVNRIKALQNSIQEQVVEMKRLEVDIDIKIRACKGSCARSFDYQVDKEGYDNIQKQLTQASSIDMHPDFQATLSTLKMRPPEHFKLEMQALNVFNNIKQMQVVLERPETDSSQGETYHV----------------------------------------------------------------------------AEARGDSSP---------------------PHTSKLVTSAHGRET-----PSLVDSSVHRCTRIVTKKVISPDGPREEIVEKMVSSDGSDCSHLQG--YHFSGTGDFHKLDRFQPDSFFTHDTSSRVG-----GKDKFTDLGEE--AAGSASHSRTVVTSSSSFNKGGSTFETKSLKTDQSAEDTPDFQDYSGKDCDDIRQKHTFGAKSGIFKIKPEGSSKVLSVYCDQETTLGGWLLIQQRMDGSVNFNRTWQDYKRGFGSVDGKGRGELWLGNENIHLLTQNDLRVELEDWDGNAAYAEYIMQVGTEAEGYALAVSSYEGTAGDALVAGWLEEGSEYTSHAQMQFSTFDRDQDRWEESCAEVYGGGWWYNSCQAANLNGIYYPGGHYDPRYNVPYEIENGVVWIPFRASDYSLKVVRMKIRPLDTL >XP_020957142.1 fibrinogen alpha chain isoform X1 [Sus scrofa] VRLFCLVLTVVGTVQMAEVQKGEFLAEGGGVRGPRLTERHQSACKESDWPFCSDEDWNIKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFDYQKNNKDSSTLSRNIIELLRGDFSNANNNDNIYSQVSEELRSRIEILKRKVLEKVQHIHLLQKNVRDQLIEMKRLEVDIDIKIRSCKGSCSRALEHKVDLKDYENQQKQLDQVIAINLLPSRDRYLPLIKISPPADFKTTPPEWKALLETRQVKMVLERVGGDERGGSIHGPGSVPGT----GSPGGLKPGSYGPGGPPDPGSAGTWKPGRPEPGSTGTWDSGHPDPGRPEPGSTGTWSSGSGSLRPDSSGPGDTTPSNPDWGTFKESGSVSPGTKSEVHTSKLVTSKGDKDIVIGKEKVTSGTTHRSCSKTITKTVTKADGRTETIKEVINSEDGSDCGGT-DVEHMLPGKGSLDEFFHRHRD---ETSVLKEFDGKTHPGSDL------ASSSSKISSHSKQTITK--TINREGGAVESKSYKMEDEADSEEGLDTRPARDCGDALQTHPSGAQSGIFNIELPGSSKIFSVYCDQETDLGGWLLIQQRTDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEYLHLLTLRGLRVELEDWAGKGAYAEYHLRVGSEAEGYALQVSSYKGTAGDALIEGSPEEGSEYTSHAGMQFSTFDRDADKWEENCAEVYGGGWWYNNCQAANLNGIYYTGGSYDPRDNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLVTP >XP_003822627.2 fibrinogen alpha chain [Pan paniscus] MRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDWNYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSANNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRHLPLIKMKPPGNFKSAPPEWKALTDMPQMRMELERPGRNERGDSTYGTGSETESPRNPSSAGSWNPGSSGPGSSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSPRPGSTGTWHSESGSFRPDSSGSGNGRPTNPDWGTFEESGNVSPGTRREYHTEKLVTSKGDKELTTGKEKVTSGTTRRSCSKTVTKTVIGHDGHKEVTKEVVTSEDGSDCPEAIDLG-TLSGIGTLDEFRHRHPDAFFDTAIFREFVSETESESGIFTNTKESPSRGKTSSHSKQF-TSGTSYSRGGSTFESKSYKMADEAGSEADHESRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQRGLRVELEDWAGNEAYAEYHFRVGSEAEGYALQVSSYEGTAGDALIEGSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENGVVWVSFRGADYSLRAVRMKIRPLVTQ >XP_019684378.1 fibrinogen alpha chain [Felis catus] LKIFCLALSVVGTVWTGDVQEGEFIAEGGGVRGPRIVEGHHSVCKETDWPFCSDEDWNYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFDYQKNNKDSSLLTGNVMELVRGDFATGNNNDNTFSQVSEDLRSRIEILKRKVLEQVQHIQLLQKNVRDQLIDMKRLEVDIDIKIRSCQGSCSRALERRTDLKYYEDQQKQLEQVIAKDLLPSRDTYLPLLKMRTPGEYKHAPAEWKALMETQQMKITLERSGTDGPGDSAHGTGSVPESPRNPGSSGTWNPGSSGPGSSSTPGSSGAWNPGSSGPGSSGAWNPGSSGPGSSGPGSGSTWTPQPGSFRPDSLGHGDTRPTKQEWGTVEESGSVSPGTKKEYHTGKLITSKGDKELLIGNEKVTSGTTHRSCSKTVTKTVIGPDGRKEVIKEVVNSEDGSDCD------HAF--SGSLGDLHSRHPDSFFESATLREFES---SESDIFTHL---PSSGKTSTHSKQLVTTSKTYNRGDSTFESKSFKVAGEAGSEAEHEARPARDCDDVLQTHPAGAQSGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLDDKGEGEFWLGNEYLHLLTLRGLRVELEDWAGNLAYAEYHLRVGSEAEGYPLQVSSYQGTAGDALIEGSVEEGTEYTSHAGMQFSTYDRDADLWEENCAEVYGGGWWYNSCQAANLNGIYYPGGSYDPRNNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLVTH >XP_004017232.4 fibrinogen alpha chain [Ovis aries] VRDLCLVLSLVGAIQTADDSGGEFLAEGGGVRGPRLVEKQQSTCKETGWPFCADEDWGEKCPSGCRMKGLIDEVNQDFTGRINKLRDSLFNYQKTNKDSNTLTKNIVEILRGDFAKANNNDNTFNQVSEDLRSRIEILRRKVIEQAQHINLLQKNVKNQLVDMKRLEVDIDIKIRSCKGSCSRALEHKVDLEDYKNQQKQLEQVIAINLLPSRDTYLSLIKMSAPRELKSAPPEWKALLEMQQMKMVLENFGGDGRGDSVHRTGLAPESPRKPGSIGNVNPGSYGPGSSPEPGSAGTWNTGRPEPGSAGTWNTGRPEPGRPEPGSAGTWSSGSSSFRPDSSGHGNIRPSSPDWGTFREEGSVSSGTKKEFHTGKLVSAKGEKELLIGNEKVSSGTTRRSCSKVITKTVTNAEGHTETTKEVVKSEDGSDCGDA-DFDHTFSTRGNLEDFFHRNSD------KLHEFDGKTRLESDV-------SSGSKTSAHSKQFLSSSTTISRGGSALESKNFKMADEAESIEDLGARPARDCYDVLQTHPSGAQSGIFSIKLPGSSKIFSVYCDQETGLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEYLHLLTLRGLRVELEDWAGKGAYAEYHLRVGSEAEDYALEVSSYKGTAGDALIEGSVEEGTEYTSHTGMRFSTFDRDADKWEDNCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRDNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLVTQ >XP_018880884.1 fibrinogen alpha chain [Gorilla gorilla gorilla] MRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDWNYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLLEYQKSNKDSHSLTTNIMEILRGDFSSANNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSCRGSCSRALAREVDLKDYEDQRKQLEQVIAKDLLPSRDRHLPLIKMKPPGNFKSAPPEWKALTDMPQMRMELERPGRNERGDSTYGTGSETESPRNPSSAGSWNPGSSGPGSTSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSPRPGSTGIWHSESGSFRPDSSGSGNARPTNPDWGTFEESGNVSPGTRREYHTEKLVTSKGDKELTTGKEKVTSGTTRRSCSKTVTKTVIGPAGHKEVTKEVVTSEDGSDCPEAMDLG-TLSGVGTLDEFRHRHPDAFFDTAMFGEFVSETESESGIFTNTKESPSRGKTSSHSKQF-TSSTSYSRGGSTFESKSYKMADEAGSEADHESRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQRGLRVELEDWAGNEAYAEYHFRVGSEAEGYALQVSSYEGTAGDALIEGSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENGVVWVSFRGADYSLRAVRMKIRPLLTQ >XP_013227609.1 fibrinogen alpha chain [Columba livia] MKILCVLLCL-NLAWAQDG-ETTFEKEGAGVRGPRIVEHSQSTCQEKNWPFCADDDWGIKCPSGCRMQGLIDETDKDYSQRIDKIKKLLAENQNNYKKSNRVIVETINVLKPNLDSAQEIDENYGHVSGELRRRIVTLKQRVVTQVNRIKALQSSIQEQVAEMKRLEVDIDIKLRACKGSCARSFDYQVDKESYDNIQKQLTQANSINLHPELQTTLSTLKMRPPEHFKHEMQALNIINNIRQMQAVLERSETDISRGDSYHV----------------------------------------------------------------------------SESRGDGH----------------------SHTSKLVTPIHERET-----LSLGGSTVRRCTKTTTKKIVGPDGPREEVVEKMVSSDGLDCSFLQGAGYHVGGTGDLHKLEKLFPESFFSPDTSSHLGVSTHEGKGKFTDLRED--PSGSASHSKTVVTSSSSFNKGGSTFETKSLKTDESAEDIPDFQPNTGKDCDDIRQKHTSGAKSGIFKIKPAGSNKVLSVYCDQETTLGGWLLIQQRMDGSVNFNRTWQDYKRGFGSVDGRGRGEFWLGNENIHLLTQNDLRIELEDWDGNAVYAEYIVQVGSEEEGYALAVSSYEGTAGDALITGWLEEGSEYTSHAQMRFSTFDQDQDHWEESCAEVYGGGWWYNSCQAANLNGIYYLGGHYDPRYNVPYEIENGVVWLPFRASDYSLKIVRMKIRPIETL >XP_005691214.3 PREDICTED: fibrinogen alpha chain [Capra hircus] VRDLCLVLSLVGAIQTADDSGGEFLAEGGGVRGPRLVEKQQSTCKETGWPFCADEDWGEKCPSGCRMKGLIDEVNQDFTSRINKLRDSLFNYQKNNKDSNTLTKNIVEILRGDFAKANNNDNTFNQVSEDLRSRIEILRRKVIEQAQHINLLQKNVKNQLVDMKRLEVDIDIKIRSCKGSCSRALEHKVDLEDYKNQQKQLEQVIAINLLPSRDTYLSLIKMSAPRELKSAPPEWKALLEMQQMKMVLENFGGDGRGDSVHRTGLAPESPRKPGSIGNVNPGSYGPGSSPEPGSAGTWNTGRPEPGSAGTWNTGRPEPGRPEPGSAGTWSSGSSSFRPDSSGHGNIRPSSPDWGTFREEGSVSSGTKKEFHTGKLVSAKGEKELLIGNEKVTSGTTRRSCSKVITKTVTNAEGHTETTKEVVKSEDGSDCGDA-DFDHTFSTRGNLEDFFHRNSD------KLHEFDGKTRLESDV-------SSGSKTSAHSKQFLSSSTTISRGGSALESKNFKMADEAESIEDLGARPARDCYDVLQTHPSGAQSGIFSIKLPGSSKIFSVYCDQETGLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEYLHLLTLRGLRVELEDWAGKGAYAEYHLRVGSEAEDYALEVSAYKGTAGDALIEGSVEEGTEYTSHTGMRFSTFDRDADKWEDNCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRDNSPYEIENGVVWVPFRGADYSLRAVRMKIRPLVTQ >XP_006034117.1 LOW QUALITY PROTEIN: fibrinogen alpha chain [Alligator sinensis] MRILCILLCL-SIVWAVEE-GSTFEEEGGVARGPRLSERAQASCKEKSWPFCSDDQWGQKCPSGCRMQGLIDDTNSDFNHRLDKIRKLLDDNENKYKKSKIITTETFNSMKGTLVSGQESDSKYGQVIEDLRRRIVSLKTKVIAQIERIYGLQNSIREQVLEMKRMEVDIDIKIRACKGSCVKSSDYHVDKESYDNIQRQLTQASSINLQSDLSSIIRVLKIKPLPHFKADWPEWNFLNKMQQLELVLESPETGPFPVDTYSS----------------------------------------------------------------------------SVHKGDGEP----------------------QGSKFVHTTYGKET----RFGEGVSTHYTCTKTVTKKVVGPDGPREEVVEKYTSSDGSDCSHLRGLGVTTGGGGDMSDLDKVF--SFFSTDSSGFIGGSSHQGSDASGELREGPYSKTQSGVSSETVVSSTSFNKGGSTFETKSLKTDESTEDGPDFKRTTGTDCEDIRQKHTSGAKSGIFRIKPTGSSKVLSVYCDQETTLGGWLLIQQRIDGSVNFNQTWQDYKKGFGSVDAKGKGELWLGNENIHLLTQKDLRVELEDWAGNTVYAEYNIHVGSESQGYVLSVSNYEGTAGDALITGSVDEGSEYTSHANMKFSTFDRDSDQWEENCAEVHGGGWWYNNCQAANLNGMYYLGGQYDPRNNIPYEVENGVVWIPFRASDYSLKIVRMKIRPNKTL >XP_043340007.1 fibrinogen alpha chain [Cervus canadensis] MRDLCLVLSLVGAVQAADGSSSDFLAEGGGVRGPRLVERQQSTCKETGWPFCADEDWGEKCPSGCRMKGLIDEVNQDFTSRINKLRDSLFNYQKNNKDSNTLTKNIVELLGGDFAKANNNDNTFNQVSEDLRSRIEILRRKVIEQVQYINLLQKNVRDQLVDMKRLEVDIDIKIRSCKGSCSRALEHKVDLEDYKDQQKKLEQVIAIDLLPSRDVYLPLIKMSASREFKKVPSEWKALLEMQQTKMVLETFGGDGRGDSVHGTGLAPERPRRPSSIGNVNPGSYGPGGSPEPGSAGTWNTGRPEPGSAGTWNTGRPEPGRPEPGSAGTWSSGSSSFRPDSSGHGNTRPSSPDWGTFREEGSVSSGTKKEFHTGKLVTTKGEKELLIGNEGVSSGTTRRSCSKVITKTVTNADGRTETTKEVVKSEDGSDCGDA-DLDRTLSVRGNLDDFFSRNND------KLREFDGKTGLESGV-------SSSGKTSTQSKQFVSSSTTINRGGSAIESKSFKMADEAESVEDLGARPARDCYDVLQTHPSGAQSGIFSIKLPGSSKIFSVYCDQETGLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEYLHLLTLRGLRVELEDWAGKGAYAEYHLRVGSEAEGYALEVSSYKGTAGDALIEGSVEEGTEYTSHTGMRFSTFDRDADKWEDNCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRDNSPYEIENGVVWVPFRGADYSLRAARMKIRPLGHN >XP_043758605.1 fibrinogen alpha chain [Cervus elaphus] MRDLCLVLSLVGAVQAADGSSSDFLAEGGGVRGPRLVERQQSTCKETGWPFCADEDWGEKCPSGCRMKGLIDEVNQDFTSRINKLRDSLFNYQKNNKDSNTLTKNIVELLGGDFAKANNNDNTFNQVSEDLRSRIEILRRKVIEQVQYINLLQKNVRDQLVDMKRLEVDIDIKIRSCKGSCSRALEHKVDLEDYKDQQKKLEQVIAIDLLPSRDVYLPLIKMSASREFKKVPSEWKALLEMQQTKMVLETFGGDGRGDSVHGTGLAPERPRRPSSIGNVNPGSYGPGGSPEPGSAGTWNTGRPEPGSAGTWNTGRPEPGRPEPGSAGTWSSGSSSFRPDSSGHGNTRPSSPDWGTFREEGSVSSGTKKEFHTGKLVTTKGEKELLIGNEGVSSGTTRRSCSKVITKTVTNADGRTETTKEVVKSEDGSDCGDA-DLDRTLSVRGNLDDFFSRNND------KLREFDGKTGLESGV-------SSSGKTSTQSKQFVSSSTTINRGGSAIESKSFKMADEAESVEDLGARPARDCYDVLQTHPSGAQSGIFSIKLPGSSKIFSVYCDQETGLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEYLHLLTLRGLRVELEDWAGKGAYAEYHLRVGSEAEGYALEVSSYKGTAGDALIEGSVEEGTEYTSHTGMRFSTFDRDADKWEDNCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRDNSPYEIENGVVWVPFRGADYSLRAARMKIRPLGHN >KAB0370205.1 hypothetical protein FD755_018167 [Muntiacus reevesi] MQVQCL---------AADGSSGEFLTEGGGVRGPRLVERQQSTCKETGWPFCADEDWGEKCPSGCRMKGLIDEVNQDFTSRINKLRDSLFNYQKNNKDSNTLTKNIVELLGGDFAKANNNDNTFNQVSEDLRSRIEILRRKVIEQVQHINLLQKNVRDQLVDMKRLEVDIDIKIRSCKGSCSRALEHKVDLEDYKDQQKTLEQVIAIDLLPSRDVYLPLIKMSASREFKKVPSEWKALLEMQQTKMVLETFGEDGRGDSVHGTGLAPERPRRPSSTGNVNPGSYGSG-----GTRKCWHL-----------------XGRPEPGSAGTWSSGSSSFRPDSSGHGNTRPSSPDWGTFREEGSVSSGTKKEFHTGKLVTTKGEKELLIGNEGVSSGTTRRSCSKVITKTVTNADGRTETTKEVVKSEDGSDCGDA-DLDRTLSVRGNLDDFFSRNSD------KLHEFDGKTGLESGV-------SSSGKTSTQSKQFVSSSTTINRGGSAIESKSFKMADEAESVEDLGARPARDCYDVLQTHPSGAQSGIFSIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEYLHLLTLRGLRVELEDWAGKGAYAEYHLRVGSEAEGYALDVSSYNGTAGDALIEGSVEEGTEYTSHTGMQFSTFDRDADKWEDNCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRDNSPYEIENGVVWVPFRGADYSLRAARMKIRPLGHN >KAB0358664.1 hypothetical protein FD754_002820 [Muntiacus muntjak] MQVQCL---------AADGSSGEFLTEGGGVRGPRLVERQQSTCKETGWPFCADEDWGEKCPSGCRMKGLIDEVNQDFTSRINKLRDSLFNYQKNNKDSNTLTKNIVELLGGDFAKANNNDNTFNQVSEDLRSRIEILRRKVIEQVQHINLLQKNVRDQLVDMKRLEVDIDIKIRSCKGSCSRALEHKVDLEDYKDQQKTLEQVIAIDLLPSRDVYLPLIKMSASREFKKVPSEWKALLEMQQTKMVLETFGEDGRGDSVHGTGLAPERPRRPSSTGNVNPGSYGSG-----GTRKCWHL-----------------XGRPEPGSAGTWSSGSSSFRPDSSGHGNTRPSSPDWGTFREEGSVSSGTKKEFHTGKLVTTKGEKELLIGNEGVSSGTTRRSCSKVITKTVTNADGRTETTKEVVKSEDGSDCGDA-DLDRTLSMRGNLDDFFSRNSD------KLHEFDGKTGLESGV-------SSSGKTSTQSKQFVSSSTTINRGGSAIESKSFKMADEAESVEDLGARPARDCYDVLQTHPSGAQSGIFSIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEYLHLLTLRGLRVELEDWAGKGAYAEYHLRVGSEAEGYALDVSSYNGTAGDALIEGSVEEGTEYTSHTGMQFSTFDRDADKWEDNCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRDNSPYEIENGVVWVPFRGADYSLRAARMKIRPLGHN >NP_001080329.1 fibrinogen alpha chain precursor [Xenopus laevis] AALITLLLCFAGSVWSEG--EGGIEAQGGSIRGPRIMESAESDCKEKNWPICSDEDWGPKCPSGCRIQGLTDKTDKDFAKRIETIKQKFKDGEISYKSIDVQTKQTYENLKNNLIQAQQSDGKYNQASEDLRKKIEYLKLKVSNQVERIKSLQRNIRDQVVEMKRLEVDIDIKIRACKGSCAKNTDYKVDLDSYNNIQKLLLQAETTDLSN--EMSIRVLKMKPDSRYKTQEAEFPIFKDINQYSFVLEGTKEEVSSIGTSVV-------------------------------------------------------------------------FP-S---GSGKDVD-------------------FQ-----GSKGTQSGVKGGDQSTKVSRTVSCTKTKKKRVITPEGPKEEIIESY--SGGAECEKLGKFSIKISGSSSLGDISKI-PSEFLSSSYSKGV------THDAFSDLGED--KEGSSTYTKTVVSSSRGSTKDGTQFDIKSMKSDNSEEDRPDFQDYTGKDCDDIRQKHSSGAKSGIFKIRPEGSSKVLTVYCDQDTQLGGWILIQQREDGSVNFNRTWQDYKNGFGSVDASGKGEVWLGNENIHLLTQKDLRIELEDWSGEKAYAEYNFQLGSESEGFILKVSQYEGTAGDALIEGSKEDG-EYTSHFNMKFSTYDRDSDKWEENCAEMYGGGWWYNNCQASNLNGIFYIGGQYDPRNSVPYEIENGVVWVPFKAADYSLKTVRMKIRPVETS >XP_040187953.1 fibrinogen alpha chain-like [Rana temporaria] ATLVTVLLCLASTAWTAE----DFEDVGATGRGPRILEQAAAGCKEKNWPVCSDEDWGPKCPSGCRVQGLTTQTDKEFSKRIDAIKQKLKDGESNYKSIDVRTKETYELVKGNLVAAQQTDGAYNQVTENLRRKIEFLKTKVTIQIDRIKLLQKNIRNQVVEMKRLEVDIDIKLRSCKGSCAKGVEYNVDYESYENIQKQLLQAESTDLRP--NVAIPVLKMRPDSRYKTQKEQYPIFSDIKQYSFVLEGKSKEVQPVSTSVS--------------------------------------------------------------------------------GSTKEQP-------------------TQTFVIYGDKGTQPVVSGGDK-TSVSRVITCTKTITKKIVGPDGPREEVFET---TSGDECEKLEALKVKVTGSGSAGGV-HI-PSDFLSGKQSSST------KTQTSFTNGEDQSSSGSTTYSKTVVSSSSGSTKDGTEWGTK-YKSGNSEEDVPDFSSSTGSDCADILQKHSSGGKSGIFKIKPEGSQTELSVYCDQDTQIGGWLLIQQREDGSVNFNRTWQDYKHGFGSVDANGKGELWLGNKYIHMLSQNELRVELEDWSGKQAFAEYIFRLGSESEGFALHASSYEGLAGDALTEGSKEDS-ENTSHDKMKFSTYDRDNDKWEENCAEMYGGGWWYNNCQAANLNGIYYTGGQYDPRNNVPYEIENGVVWLSFKPDDYSLKTVKMKIRPVETA >NP_001181918.1 fibrinogen alpha chain precursor [Danio rerio] MKFTHSLLCLFVAVSSALAE----EDTVVNPRGARPIEHAQDTCQTKEWPGCTDDDWGSKCPSGCRVQGLMDKADHDLLKKIEKIRRLLVEGQKLYRSADEVSKTTYTYLREKLTSNSGYDNRYMSLAEQLRQRITDIKIKIDRQLRLLDALKSQVKDQVVVMQRLEVDIDIKLRTCKGSCASYSEFSVDRESYVTLDKQMDNLNAMRVQSVETVSLGIMKSRPPTIYKSAEQKL-LFGDVGQMQLSLEAEGSTAATVSK----------------------------------------------------------------------------FP-TSGTGSTSQ----------------------------------------------TSSKQCTKSVRKVITTKDGPVEKV-EVS--SSGPGCDDLGKLGLSRDGLKI----------------TS---------------DLGGF--ASSSSSTSTKTVSDSKSYSK--TTLTSDPIFGGDVEEDMPDIHGFVGGDCVEIQQKHVNGGQSGMFKIKPAGSEEVVEVYCDQSTGLGGWTLVQQREDGSVNFNRTWKEYLNGFGQIDKQGKGEIWIGNKFLHLLTQKELRVELQDWTGAEAYAEYNIKVGSEAEGFPLTASDYDGDAGDALVRGHPNLGS-FLSHAGMKFSTFDRDSDKWEENCAEMYGGGWWYNNCQSANLNGIYYKGGQYDPATKVPYEIENGVVWLPFKPADYSLKVVRMKIRPV--- >XP_030287455.1 fibrinogen alpha chain-like isoform X1 [Sparus aurata] MQRLGLLVCFI-IGVTQS-------AVQVDPRGARPVEHSEKCASEKEWPFCTTDEWGPKCPSGCRIEGLMNKYDHSLLKRIEKIRSLLDENTVKQRSTDSATKQTYDYLKDKLTTDAGHNNNYYDLAQNLRQRITDMKIKIDRQLRILAALKDRVKDQVVEMQRLEVDVDIKLRSCKGSCQGYAEFQVDHEDYVVLDKQINQLDSQSAQRIDSVTLYVMKSRPDSIYKSAQRREDVFTDVPMVQLLLGEEGSSSATISKQGT------------------------------------------------------------------SYSSPTFSSSSSSSSSSSSSSSSSS--------------SSTPSKSITELGGSSHIQGLGGSATTTQTISCTKSTRRTIVTKDGPVEKVEEVY--EGGPECQALGDSS---GGMGA--------------------------------------------------------GGAKGSLLGNTNPFGADNTEDDIPDFHDYVGKDCVEAYQNHLKGETNGLFNIRPGGSTQVVEVYCQQEGLMGGWMLVQQRENGALSFNRTWAEYRTGFGSVDAKGKGELWLGNQNLHLLTNQGLKVELEDWEGGVAIAEYIIRVGSEEEGYPLHVSGYTGDAGDALVMPKSDMAS-YLSHNGMKFSTFDKDNDRWEENCAEMYGGGWWYNNCQSANLNGMYYQ-GTYDPEKNKPYEIENGVVWVTYKTANYSLKTVRMFIRSSAF- >XP_015801603.1 PREDICTED: fibrinogen alpha chain [Nothobranchius furzeri] MKMMRLLVCLVCVAVTQV-------ASQVDPRGARPVEPSDKCSTQKEWPFCTDDDWLSKCPSGCRIQGLMDKADHELLKKIEKIRSLLNQNKAKHRSTDQVSKQTYDYLRDRLTTDSGNNNNYYDLAQSLRQRITDMKIRIDNQMNTLAALKNRVKNQVTEMQRLEVDIDIKLRSCKGSCGGYSEYQVDKESYVNLDKQMRQLEAQSAQSVESVTLYVMKTSSETRFKSGQKKDDVFSEVKTLQFVLEQEGSSSATVSKPGT------------------------------------------------------------------SQLQGTPAP-LLPSSSSSSSS----------------------SKYITQLGGPGDFDNSGQDRVYTKTSSCTKSIKRTVVTKDGPVEKTEEVM--QGGPECRGMTELT---GGMSS----------------SS-------------------------SSSSSLTHTSSSSGGAKGSLLGDSDPFRDDNAEDDVPDFHDFVGKDCVDAYQKHLKGETNGLFKIKPGGST-VVEVYCHQEGIMGGWLLVQQRASGSVSFNRTWAEYRDGFGSVDAEGNGEFWLGNQLLHLLTNQSLKVELEDWEGGAATAEYSVRVGSKEEGYPLHVSGFTGDAGDALLK----------SHSGMKFSTFDKDDDKWERNCAEVYGGGWWYNSCQLANLNGVYYR-GSYDPKGSAPHQAENGVVWTTFKPATYSLKAVRMFVRPAEF- >XP_011485484.2 fibrinogen alpha chain [Oryzias latipes] MKQLVVLTCLLCVAFTQ--------DTVIDPRGARPVEHDEKCATQKEWPFCLDDDWGHKCPSGCRIQGLMDKYDHDLLKRIEYIRDQLNQHKGKYRSADQVSKQTHDYLREKLTVDAGHDNKYFELAQSLRQRITEIKIRIDRQMKVMAALKGRIREQVTEMQRLEVDIDMKLRSCKGSCATYHEYQVDQQSYVTLEKQVAQLDSQTPQNIEAATLYVMKSRPDSIYKSGQQKQDLFSDIKTLKLVLEEEGSSSATVSKPGT------------------------------------------------------------------------PFP-STSSSSSSSSSSSSG--------------SSNPSKSITELGGRGDFGGFSQASTGTKSVSCTTHMKKVVVTKAGPVERYETVT--EGGPECQGGADLT---GGLTS----------------SS-------------------------SMS-----TKSFSSGAKGGLLG--NPFEGDNAEDDLPDFHDYVGKDCVEANQKHLKGETNGLFKIKPGGSTQVVEVYCQQEGVMGGWLLVQQRESGALSFNRSWADYRGGFGSVDAQGKGEFWLGNENLHLLTSQGLKVELEDWEGGKASAEYTMRVGSEQEGFPLHVSGYTGDAGDSLAAPTSEKAS-EVTHDGMKFSAFDKDNDNWGENCAEAYGGGWWYNSCQAANLNGVYYK-GEYDPATNTPYKTENGVVWSSFKPVNYSLKTVRMLIRSAAF- >XP_006275580.1 PREDICTED: LOW QUALITY PROTEIN: fibrinogen alpha chain [Alligator mississippiensis] MRILCVLLYL-SIVWAVEE-GSTFEDEGGVARGPRLSERAQASCKEKSWPFCSDDQWGQKCPSGCRMQGLVDDTNSDFNHRLDKIRKLLDDNENKYKKSKIITTETFNSMKGTLVSGQESDSKYGQVIEDLRRRIVSLKTKVIAQIERIYGLQNSIREQVLEMKRMEVDIDIKIRACKGSCAKSFDYHVDKESYDNIQRQLTQASSINLQSDLSSIIRVLKIKPLPHFKADWPEWNFLNKMQQLELVLESPETGPFPVDTYSS----------------------------------------------------------------------------SVHKGDGEP----------------------QGSKFVHPTYGKET----HFGEGVSTHYTCTKTVTKKVVGPDGPREEVVEKYTSSDGSDCSHLRGLGVTAGGGGDMSDLDKVF--SFFSTDSSGFIGGSSHQGSDASGELREGPYSKTQSGVSSETVVSSTSFNKGGSTFETKSLKTNESTEDGPDFKRTTGTDCEDIRQKHTSGAKSGIFRIKPTGSNKVLSVYCDQETTLGGWLLIQQRIDGSVNFNQTWQDYKKGFGSVDAKGKGELWLGNENIHLLTQKDLRVELEDWAGNTVYAEYNIHVGSESQGYVLSVSNYEGTAGDALITGSVDEGSEYTSHANMKFSTFDRDSDQWEENCAEVHGGGWWYNNCQAANLNGMYYLGGQYDPRNNIPYEVENGVVWIPFRASDYSLKIVRMKIRPNETL >XP_020747240.1 fibrinogen alpha chain [Odocoileus virginianus texanus] VRDLCLVLSLVGAFQAADGSGGEFLAEGGGVRGPRLVERQQSTCKETGWPFCADEDWGEKCPSGCRMKGLIDEVNQDFTSRINKLRDSLFNYQKNNKDSNTLTKNIVELLGGDFAKANNNDNTFNQVSEDLRSRIEILRRKVIEQVQHINLLQKNVRDQLVDMKRLEVDIDIKIRSCKGSCSRALEHKVDLEDYKDQQKKLEQVIAIDLLPSRDVYLPLIKMSPSREFKRVPQEWKALLEMQQTKMVLETFGGDGRGDSVHGTGLAPERPRRPSSIGNVNPGSYGPGGSPEPGSAGTWNTGRPEPGSAGTWNTGRPEPGRPEPGSAGTWSSGSSSFRPDSSGHGNTRPSSPDWGTFREEGSVSSGTKKEFHTGKLVTTKGEKELLIGNEGVASGTTRRSCSKVITKTVTNADGRTETTKEVVKSEDGSDCGDA-DLDRTLSVRGNLDDFFSRNSD------KLHEFDGKTGLESGV-------SSSGKTSTQSKQYVSSSTTINRGGSTIESKSFKMADEAESVEDLGSRPARDCYDVLQTHPSGAQSGIFSIKLPGSSKIFSVYCDQETGLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDKGEGEFWLGNEYLHLLTLGGLRVELEDWAGKGAYAEYHLRVGSEAEGYALEVSSYKGTAGDALIEGSVEEGTEYTSHTGMRFSTFDRDADKWEDNCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRDNSPYEIENGVVWVPFRGADYSLRAARMKIRPLGHN >XP_031552222.1 angiopoietin-2-like [Actinia tenebrosa] ---------------------------------PHLIVN---------------------------------------------------------------------------------ESQSALFHYSIRGNPQPLWSKVGGSLDTTRSIVNSSRGI----------LEIK--------------HVTFSDSGIYQCNASSIXGKAL-----ATRLVVNYRP-----------------------YVKIGDNVPTCHVGHP-----KPR-------------------------------------------------------VTW----------SRSIGKLPSN---------------------------------------------RTLTRDNELTLFNVVDDSGTYVCTSDNFLGSDAAGC-------------------------------QLPVF------------VVRPPGSSLTLNCSAKGDPEQVISWRRENGALPSGRYEIRNIQASDDDIYNIFYHDCSEIYK--SGERRSGVYTIKPD-SERAFQVYCDMTTDGGGWTVFQRRQDGSVDFYRDWQQYKTGFGNLN----GEFWLGNDYIHRLTEKTLRVELEDWNRNKKYAKYSFSVGDESDKYRLKVASYSGDAGDSLI-----------SHHNNLFSTKDRDNDKHQSKCTTLFGGAWWYRACYDSNLNGKYF-GNKRD---------EKGIAWEGFH-YDLSLKYSEMKIRPISF- >XP_039268423.1 angiopoietin-related protein 2-like [Styela clava] IVVVTLFIALL---------------------------------------FCG------------HVRSQLTVVDPPIMQ----------------------------------IATGGDNNGKSNMKYDVKIRKYTV-------VRVPETPPSTTTEISTTTTTPPPDLDVN--------------HIEVQTRSTFEENLLEEDH------DCATFTLPNPRPMTSYPE------------------RRSGDEENTLRNISL-----------------------------------------------------------------W----------QESMGDLKTQIEE----------------RLAVPSLEPVRNDVRL-----QKESRFRISQLYMQLLHEIIKRDDTIEYTS------------------------------------------TIKYY------------ELKEKHKALKQQSQSQQEQIKILQTKMEEMVHRMNRMAVDDEKDEVNDTARSSYTNCVDIQL--YASKESGIYILTLPSLSRKMKVWCDFEQDPGGWTVIQRRSEGKVNFYRNFASYQRGFGSLE----GEFWLGLENIHHLTNQPLHIDMEDWSGRKTFVEYSFKLEGQDEGYRLKVAHYSGTAGDSL-----------TWHNNMKFTTKNVDNDPFARNCANYQKGGWWYNTCAHSNLNGVYYMGGHYRSK------FQDGIYWSEWRGGSYSLKHVEMKIKPSE--
PhyML tree of selected proteins (((((((XP_013227609_1_fibrinogen_alpha_chain__Columba_livia_:0.08748297,(NP_001258840_1_fibrinogen_alpha_chain_isoform_1_precursor__Gallus_gallus_:0.04618449,XP_003205398_1_fibrinogen_alpha_chain__Meleagris_gallopavo_:0.03776526):0.09699043):0.1804654,(XP_006034117_1_LOW_QUALITY_PROTEIN__fibrinogen_alpha_chain__Alligator_sinensis_:0.01109913,XP_006275580_1_PREDICTED__LOW_QUALITY_PROTEIN__fibrinogen_alpha_chain__Alligator_mississippiensis_:0.00816917):0.31339939):0.12024705,((NP_001080329_1_fibrinogen_alpha_chain_precursor__Xenopus_laevis_:0.23474311,XP_040187953_1_fibrinogen_alpha_chain_like__Rana_temporaria_:0.2892042):0.23076265,(NP_001181918_1_fibrinogen_alpha_chain_precursor__Danio_rerio_:0.34880872,(XP_011485484_2_fibrinogen_alpha_chain__Oryzias_latipes_:0.20916068,(XP_030287455_1_fibrinogen_alpha_chain_like_isoform_X1__Sparus_aurata_:0.24617783,XP_015801603_1_PREDICTED__fibrinogen_alpha_chain__Nothobranchius_furzeri_:0.22267419):0.05569437):0.34005951):0.64305006):0.14666994):0.26135229,(XP_039268423_1_angiopoietin_related_protein_2_like__Styela_clava_:2.2370182,XP_031552222_1_angiopoietin_2_like__Actinia_tenebrosa_:1.68286837):1.16140991):0.32487722,(XP_002815279_3_fibrinogen_alpha_chain_isoform_X1__Pongo_abelii_:0.02453935,((XP_003822627_2_fibrinogen_alpha_chain__Pan_paniscus_:0.00262995,XP_001136067_1_fibrinogen_alpha_chain__Pan_troglodytes_:0.00395492):0.00441499,(XP_018880884_1_fibrinogen_alpha_chain__Gorilla_gorilla_gorilla_:0.00957132,(sp_P02671_2_FIBA_HUMAN_Isoform_2_of_Fibrinogen_alpha_chain_OS_Homo_sapiens_OX_9606_GN_FGA:0.01420299,sp_P02671_FIBA_HUMAN_Fibrinogen_alpha_chain_OS_Homo_sapiens_OX_9606_GN_FGA_PE_1_SV_2:0.00000001):0.01715891):0.0024426):0.01337391):0.07751216):0.02388694,((XP_020957142_1_fibrinogen_alpha_chain_isoform_X1__Sus_scrofa_:0.14430776,(XP_005217494_2_fibrinogen_alpha_chain_isoform_X1__Bos_taurus_:0.05064469,((XP_020747240_1_fibrinogen_alpha_chain__Odocoileus_virginianus_texanus_:0.01323603,((XP_043340007_1_fibrinogen_alpha_chain__Cervus_canadensis_:0.00000001,XP_043758605_1_fibrinogen_alpha_chain__Cervus_elaphus_:0.00000001):0.00715477,(KAB0358664_1_hypothetical_protein_FD754_002820__Muntiacus_muntjak_:0.00143895,KAB0370205_1_hypothetical_protein_FD755_018167__Muntiacus_reevesi_:0.00000001):0.02719302):0.00216538):0.04294074,(XP_005691214_3_PREDICTED__fibrinogen_alpha_chain__Capra_hircus_:0.00148449,XP_004017232_4_fibrinogen_alpha_chain__Ovis_aries_:0.00397656):0.03755494):0.01308548):0.11315822):0.09303691,(XP_019684378_1_fibrinogen_alpha_chain__Felis_catus_:0.10679795,XP_038544611_1_fibrinogen_alpha_chain_isoform_X1__Canis_lupus_familiaris_:0.07881432):0.04643199):0.04023906):0.03295077,XP_002716943_1_PREDICTED__fibrinogen_alpha_chain__Oryctolagus_cuniculus_:0.19996596,(NP_001008724_1_fibrinogen_alpha_chain_isoform_1_precursor__Rattus_norvegicus_:0.05791723,NP_001104518_1_fibrinogen_alpha_chain_isoform_1_preproprotein__Mus_musculus_:0.08216432):0.14563333);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)