Click here to access PB0206 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0206 Q8WVF2 Unique cartilage matrix-associated protein UCMA C10orf49, GRP, GRP/UCMA, upper zone of growth plate and cartilage matrix associated Homo_sapiens May be involved in the negative control of osteogenic differentiation of osteochondrogenic precursor cells in peripheral zones of fetal cartilage and at the cartilage-bone interface.

DomainsGene Ontology
PF17085 (UCMA)
GO:0036122 (enables) BMP binding
GO:0001649 (involved in) osteoblast differentiation
GO:0045667 (involved in) regulation of osteoblast differentiation
GO:0045668 (involved in) negative regulation of osteoblast differentiation
GO:0048706 (involved in) embryonic skeletal system development
GO:0060392 (involved in) negative regulation of SMAD protein signal transduction
GO:0110150 (involved in) negative regulation of biomineralization
GO:0005615 (is active in) extracellular space
GO:0005576 (located in) extracellular region
GO:0005737 (located in) cytoplasm
GO:0031012 (located in) extracellular matrix

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)