Click here to access PB0205 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0205 O43852 Calumenin CALU Homo_sapiens Involved in regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. Seems to inhibit gamma-carboxylase GGCX. Binds 7 calcium ions with a low affinity (By similarity).

DomainsGene Ontology
PF13202 (2_EF-hand_5)
PF13833 (EF-hand_8)
GO:0005509 (enables) calcium ion binding
GO:0005515 (enables) protein binding
GO:0046872 (enables) metal ion binding
GO:0008150 (involved in) biological_process
GO:0005576 (located in) extracellular region
GO:0005783 (located in) endoplasmic reticulum
GO:0005788 (located in) endoplasmic reticulum lumen
GO:0005789 (located in) endoplasmic reticulum membrane
GO:0005794 (located in) Golgi apparatus
GO:0016020 (located in) membrane
GO:0016529 (located in) sarcoplasmic reticulum
GO:0033018 (located in) sarcoplasmic reticulum lumen
GO:0042470 (located in) melanosome

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)