Click here to access PB0195 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0195 O15232 Matrilin-3 MATN3 DIPOA, EDM5, HOA, OADIP, OS2, SEMDBCD Homo_sapiens Major component of the extracellular matrix of cartilage and may play a role in the formation of extracellular filamentous networks.

DomainsGene Ontology
PF00092 (VWA)
PF10393 (Matrilin_ccoil)
GO:0005201 (enables) extracellular matrix structural constituent
GO:0005509 (enables) calcium ion binding
GO:0005515 (enables) protein binding
GO:0001501 (involved in) skeletal system development
GO:0030198 (involved in) extracellular matrix organization
GO:0051216 (involved in) cartilage development
GO:0005576 (located in) extracellular region
GO:0005788 (located in) endoplasmic reticulum lumen
GO:0031012 (located in) extracellular matrix
GO:0062023 (located in) collagen-containing extracellular matrix
GO:0120216 (part of) matrilin complex

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)