Click here to access PB0192 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0192 Q12841 Follistatin-related protein 1 FSTL1 FRP, FSL1, MIR198, OCC-1, OCC1, tsc36, follistatin like 1 Homo_sapiens Initiates various signaling cascades by activating different receptors on the cell surface such as DIP2A, TLR4 or BMP receptors (PubMed:20054002, PubMed:22265692).

DomainsGene Ontology
PF07648 (Kazal_2)
PF09289 (FOLN)
GO:0005509 (enables) calcium ion binding
GO:0005515 (enables) protein binding
GO:0008201 (enables) heparin binding
GO:0030154 (involved in) cell differentiation
GO:0030510 (involved in) regulation of BMP signaling pathway
GO:0043066 (involved in) negative regulation of apoptotic process
GO:0043542 (involved in) endothelial cell migration
GO:0045446 (involved in) endothelial cell differentiation
GO:0061484 (involved in) hematopoietic stem cell homeostasis
GO:0005576 (located in) extracellular region
GO:0005615 (located in) extracellular space
GO:0005788 (located in) endoplasmic reticulum lumen
GO:0070062 (located in) extracellular exosome

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)