PB0191
DATABASE


Click here to access PB0191 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0191 Q07507 Dermatopontin DPT TRAMP Homo_sapiens Seems to mediate adhesion by cell surface integrin binding. May serve as a communication link between the dermal fibroblast cell surface and its extracellular matrix environment. Enhances TGFB1 activity. Inhibits cell proliferation. Accelerates collagen fibril formation, and stabilizes collagen fibrils against low-temperature dissociation (By similarity).

DomainsGene Ontology
PF14704 (DERM)
GO:0005201 (enables) extracellular matrix structural constituent
GO:0005515 (enables) protein binding
GO:0007155 (involved in) cell adhesion
GO:0008285 (involved in) negative regulation of cell population proliferation
GO:0030199 (involved in) collagen fibril organization
GO:0005576 (located in) extracellular region
GO:0005615 (located in) extracellular space
GO:0062023 (part of) collagen-containing extracellular matrix

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences


Created by Puigbo and Nakamura @ University of Turku (2022)