Click here to access PB0189 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0189 P61626 Lysozyme C LYZ LYZF1, LZM Homo_sapiens Lizozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.

DomainsGene Ontology
PF00062 (Lys)
GO:0003796 (enables) lysozyme activity
GO:0003824 (enables) catalytic activity
GO:0016787 (enables) hydrolase activity
GO:0016798 (enables) hydrolase activity, acting on glycosyl bonds
GO:0042802 (enables) identical protein binding
GO:0001895 (involved in) retina homeostasis
GO:0006954 (involved in) inflammatory response
GO:0008152 (involved in) metabolic process
GO:0019730 (involved in) antimicrobial humoral response
GO:0019835 (involved in) cytolysis
GO:0031640 (involved in) killing of cells of another organism
GO:0042742 (involved in) defense response to bacterium
GO:0050829 (involved in) defense response to Gram-negative bacterium
GO:0050830 (involved in) defense response to Gram-positive bacterium
GO:0005576 (located in) extracellular region
GO:0005615 (located in) extracellular space
GO:0035578 (located in) azurophil granule lumen
GO:0035580 (located in) specific granule lumen
GO:0070062 (located in) extracellular exosome
GO:1904724 (located in) tertiary granule lumen

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)