Click here to access PB0177 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0177 P20062 Transcobalamin-2 TCN2 D22S676, D22S750, II, TC, TC II, TC-2, TC2, TCII Homo_sapiens Primary vitamin B12-binding and transport protein. Delivers cobalamin to cells.

DomainsGene Ontology
PF01122 (Cobalamin_bind)
PF14478 (DUF4430)
GO:0005515 (enables) protein binding
GO:0031419 (enables) cobalamin binding
GO:0046872 (enables) metal ion binding
GO:0006811 (involved in) ion transport
GO:0015889 (involved in) cobalamin transport
GO:0005576 (located in) extracellular region
GO:0005615 (located in) extracellular space
GO:0005768 (located in) endosome
GO:0043202 (located in) lysosomal lumen

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)