Click here to access PB0172 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0172 Q9NQ30 Endothelial cell-specific molecule 1 ESM1 endocan Homo_sapiens Involved in angiogenesis; promotes angiogenic sprouting. May have potent implications in lung endothelial cell-leukocyte interactions.

DomainsGene Ontology
PF00219 (IGFBP)
GO:0005171 (enables) hepatocyte growth factor receptor binding
GO:0005178 (enables) integrin binding
GO:0005515 (enables) protein binding
GO:0001525 (involved in) angiogenesis
GO:0002040 (involved in) sprouting angiogenesis
GO:0008284 (involved in) positive regulation of cell population proliferation
GO:1902204 (involved in) positive regulation of hepatocyte growth factor receptor signaling pathway
GO:0005576 (located in) extracellular region

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)