Click here to access PB0164 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0164 Q8N8U9 BMP-binding endothelial regulator protein BMPER CRIM3, CV-2, CV2 Homo_sapiens Inhibitor of bone morphogenetic protein (BMP) function, it may regulate BMP responsiveness of osteoblasts and chondrocytes.

DomainsGene Ontology
PF00093 (2_VWC)
PF00094 (VWD)
PF01826 (TIL)
PF08742 (C8)
GO:0001568 (involved in) blood vessel development
GO:0001657 (involved in) ureteric bud development
GO:0002043 (involved in) blood vessel endothelial cell proliferation involved in sprouting angiogenesis
GO:0007182 (involved in) common-partner SMAD protein phosphorylation
GO:0010594 (involved in) regulation of endothelial cell migration
GO:0030509 (involved in) BMP signaling pathway
GO:0030514 (involved in) negative regulation of BMP signaling pathway
GO:0032880 (involved in) regulation of protein localization
GO:0042118 (involved in) endothelial cell activation
GO:0045765 (involved in) regulation of angiogenesis
GO:0048839 (involved in) inner ear development
GO:0060393 (involved in) regulation of pathway-restricted SMAD protein phosphorylation
GO:0070374 (involved in) positive regulation of ERK1 and ERK2 cascade
GO:1903672 (involved in) positive regulation of sprouting angiogenesis
GO:0031012 (is active in) extracellular matrix
GO:0005576 (located in) extracellular region
GO:0005615 (located in) extracellular space

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)