Click here to access PB0155 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0155 P51884 Lumican LUM LDC, SLRR2D Homo_sapiens

DomainsGene Ontology
PF01462 (LRRNT)
PF13516 (LRR_6)
PF13855 (3_LRR_8)
GO:0005201 (enables) extracellular matrix structural constituent
GO:0005515 (enables) protein binding
GO:0005518 (enables) collagen binding
GO:0030021 (enables) extracellular matrix structural constituent conferring compression resistance
GO:0007601 (involved in) visual perception
GO:0030199 (involved in) collagen fibril organization
GO:0032914 (involved in) positive regulation of transforming growth factor beta1 production
GO:0045944 (involved in) positive regulation of transcription by RNA polymerase II
GO:0005576 (located in) extracellular region
GO:0005615 (located in) extracellular space
GO:0005796 (located in) Golgi lumen
GO:0031012 (located in) extracellular matrix
GO:0043202 (located in) lysosomal lumen
GO:0070062 (located in) extracellular exosome
GO:0005583 (part of) fibrillar collagen trimer
GO:0062023 (part of) collagen-containing extracellular matrix

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)