Click here to access PB0151 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0151 P13942 Collagen alpha-2(XI) chain COL11A2 DFNA13, DFNB53, FBCG2, HKE5, OSMEDA, OSMEDB, PARP, STL3, collagen type XI alpha 2 chain Homo_sapiens May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils.

DomainsGene Ontology
PF01391 (6_Collagen)
PF01410 (2_COLFI)
PF02210 (Laminin_G_2)
GO:0005201 (enables) extracellular matrix structural constituent
GO:0005515 (enables) protein binding
GO:0030020 (enables) extracellular matrix structural constituent conferring tensile strength
GO:0030674 (enables) protein-macromolecule adaptor activity
GO:0046872 (enables) metal ion binding
GO:0001501 (involved in) skeletal system development
GO:0007605 (involved in) sensory perception of sound
GO:0030198 (involved in) extracellular matrix organization
GO:0030199 (involved in) collagen fibril organization
GO:0051216 (involved in) cartilage development
GO:0060021 (involved in) roof of mouth development
GO:0060023 (involved in) soft palate development
GO:0005615 (is active in) extracellular space
GO:0031012 (is active in) extracellular matrix
GO:0005576 (located in) extracellular region
GO:0005788 (located in) endoplasmic reticulum lumen
GO:0062023 (located in) collagen-containing extracellular matrix
GO:0005581 (part of) collagen trimer
GO:0005592 (part of) collagen type XI trimer

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)