Click here to access PB0150 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0150 Q9HCB6 Spondin-1 SPON1 VSGP/F-spondin, f-spondin Homo_sapiens Major factor for vascular smooth muscle cell.

DomainsGene Ontology
PF00090 (5_TSP_1)
PF02014 (Reeler)
PF06468 (Spond_N)
PF19028 (TSP1_spondin)
GO:0062023 (colocalizes with) collagen-containing extracellular matrix
GO:0005201 (enables) extracellular matrix structural constituent
GO:0005515 (enables) protein binding
GO:0046872 (enables) metal ion binding
GO:0050693 (enables) LBD domain binding
GO:0007155 (involved in) cell adhesion
GO:0010954 (involved in) positive regulation of protein processing
GO:0032092 (involved in) positive regulation of protein binding
GO:1902430 (involved in) negative regulation of amyloid-beta formation
GO:1902993 (involved in) positive regulation of amyloid precursor protein catabolic process
GO:0031012 (is active in) extracellular matrix
GO:0005576 (located in) extracellular region
GO:0005615 (located in) extracellular space
GO:0005788 (located in) endoplasmic reticulum lumen

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)