Click here to access PB0143 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0143 Q8N6Y2 Leucine-rich repeat-containing protein 17 LRRC17 P37NB Homo_sapiens Involved in bone homeostasis. Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors (By similarity).

DomainsGene Ontology
PF13855 (2_LRR_8)
GO:0001503 (involved in) ossification
GO:0045671 (involved in) negative regulation of osteoclast differentiation
GO:0048539 (involved in) bone marrow development
GO:0031012 (is active in) extracellular matrix
GO:0005576 (located in) extracellular region
GO:0005615 (located in) extracellular space

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)