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| PBID | Uniprot | Name | Gene | Alternative | Organism | Uniprot Description |
| PB0142 | O00468 | Agrin | AGRN | AGRIN, CMS8, CMSPPD | Homo_sapiens | Agrin C-terminal 22 kDa fragment: this released fragment is important for agrin signaling and to exert a maximal dendritic filopodia-inducing effect. All 'z' splice variants (z+) of this fragment also show an increase in the number of filopodia. |
| Domains | Gene Ontology |
| PF00008 (2_EGF) PF00050 (Kazal_1) PF00053 (2_Laminin_EGF) PF00054 (3_Laminin_G_1) PF01390 (SEA) PF03146 (NtA) PF07648 (8_Kazal_2) |
GO:0002162 (enables) dystroglycan binding
GO:0005200 (enables) structural constituent of cytoskeleton GO:0005509 (enables) calcium ion binding GO:0005515 (enables) protein binding GO:0033691 (enables) sialic acid binding GO:0035374 (enables) chondroitin sulfate binding GO:0043236 (enables) laminin binding GO:0043395 (enables) heparan sulfate proteoglycan binding GO:0007010 (involved in) cytoskeleton organization GO:0007165 (involved in) signal transduction GO:0007213 (involved in) G protein-coupled acetylcholine receptor signaling pathway GO:0007528 (involved in) neuromuscular junction development GO:0009887 (involved in) animal organ morphogenesis GO:0009888 (involved in) tissue development GO:0030154 (involved in) cell differentiation GO:0043113 (involved in) receptor clustering GO:0043547 (involved in) positive regulation of GTPase activity GO:0045162 (involved in) clustering of voltage-gated sodium channels GO:0045887 (involved in) positive regulation of synaptic assembly at neuromuscular junction GO:0045944 (involved in) positive regulation of transcription by RNA polymerase II GO:0050808 (involved in) synapse organization GO:0051491 (involved in) positive regulation of filopodium assembly GO:0005576 (located in) extracellular region GO:0005604 (located in) basement membrane GO:0005796 (located in) Golgi lumen GO:0005886 (located in) plasma membrane GO:0016020 (located in) membrane GO:0016021 (located in) integral component of membrane GO:0030054 (located in) cell junction GO:0043202 (located in) lysosomal lumen GO:0045202 (located in) synapse GO:0070062 (located in) extracellular exosome GO:0062023 (part of) collagen-containing extracellular matrix |
| External Links | Description |
| Intact | Open source database system and analysis tools for molecular interaction data. |
| Protein Atlas | An open access resource for human proteins |
| InterPro (new pfam) | InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. |