Click here to access PB0141 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0141 Q16363 Laminin subunit alpha-4 LAMA4 CMD1JJ, LAMA3, LAMA4*-1 Homo_sapiens Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.

DomainsGene Ontology
PF00053 (3_Laminin_EGF)
PF02210 (5_Laminin_G_2)
PF06008 (Laminin_I)
PF06009 (Laminin_II)
GO:0005102 (enables) signaling receptor binding
GO:0005201 (enables) extracellular matrix structural constituent
GO:0007155 (involved in) cell adhesion
GO:0030155 (involved in) regulation of cell adhesion
GO:0030334 (involved in) regulation of cell migration
GO:0045995 (involved in) regulation of embryonic development
GO:0120163 (involved in) negative regulation of cold-induced thermogenesis
GO:0005576 (located in) extracellular region
GO:0005604 (located in) basement membrane
GO:0070062 (located in) extracellular exosome

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)