PBID | Uniprot | Name | Gene | Alternative | Organism | Uniprot Description |
PB0123 | O15230 | Laminin subunit alpha-5 | LAMA5 | Homo_sapiens | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
Domains | Gene Ontology |
PF00052 (1_Laminin_B) PF00053 (19_Laminin_EGF) PF00055 (Laminin_N) PF02210 (4_Laminin_G_2) PF06008 (Laminin_I) PF06009 (Laminin_II) |
GO:0005102 (enables) signaling receptor binding
GO:0005178 (enables) integrin binding GO:0005201 (enables) extracellular matrix structural constituent GO:0001658 (involved in) branching involved in ureteric bud morphogenesis GO:0001738 (involved in) morphogenesis of a polarized epithelium GO:0001755 (involved in) neural crest cell migration GO:0001822 (involved in) kidney development GO:0001942 (involved in) hair follicle development GO:0007155 (involved in) cell adhesion GO:0007229 (involved in) integrin-mediated signaling pathway GO:0007411 (involved in) axon guidance GO:0007517 (involved in) muscle organ development GO:0009887 (involved in) animal organ morphogenesis GO:0009888 (involved in) tissue development GO:0016331 (involved in) morphogenesis of embryonic epithelium GO:0016477 (involved in) cell migration GO:0030155 (involved in) regulation of cell adhesion GO:0030324 (involved in) lung development GO:0030334 (involved in) regulation of cell migration GO:0034446 (involved in) substrate adhesion-dependent cell spreading GO:0042127 (involved in) regulation of cell population proliferation GO:0042475 (involved in) odontogenesis of dentin-containing tooth GO:0045995 (involved in) regulation of embryonic development GO:0048754 (involved in) branching morphogenesis of an epithelial tube GO:0060271 (involved in) cilium assembly GO:0060445 (involved in) branching involved in salivary gland morphogenesis GO:0072659 (involved in) protein localization to plasma membrane GO:0098609 (involved in) cell-cell adhesion GO:0005604 (is active in) basement membrane GO:0005576 (located in) extracellular region GO:0005615 (located in) extracellular space GO:0005634 (located in) nucleus GO:0031012 (located in) extracellular matrix GO:0031594 (located in) neuromuscular junction GO:0043083 (located in) synaptic cleft GO:0070062 (located in) extracellular exosome GO:0005610 (part of) laminin-5 complex GO:0043259 (part of) laminin-10 complex GO:0043260 (part of) laminin-11 complex GO:0062023 (part of) collagen-containing extracellular matrix |
External Links | Description |
Intact | Open source database system and analysis tools for molecular interaction data. |
Protein Atlas | An open access resource for human proteins |
InterPro (new pfam) | InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. |