PB0120

DATABASE

Click here to access PB0120 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0120	P07225	Vitamin K-dependent protein S	PROS1	PROS, PS21, PS22, PS23, PS24, PS25, PSA, THPH5, THPH6, protein S	Homo_sapiens	Anticoagulant plasma protein; it is a cofactor to activated protein C in the degradation of coagulation factors Va and VIIIa. It helps to prevent coagulation and stimulating fibrinolysis.

Domains

Gene Ontology

PF00008 (EGF) PF00054 (Laminin_G_1) PF00594 (Gla) PF02210 (Laminin_G_2) PF07645 (2_EGF_CA)

GO:0004866 (enables) endopeptidase inhibitor activity GO:0005509 (enables) calcium ion binding GO:0005515 (enables) protein binding GO:0007596 (involved in) blood coagulation GO:0007599 (involved in) hemostasis GO:0010951 (involved in) negative regulation of endopeptidase activity GO:0030195 (involved in) negative regulation of blood coagulation GO:0042730 (involved in) fibrinolysis GO:0005615 (is active in) extracellular space GO:0000139 (located in) Golgi membrane GO:0005576 (located in) extracellular region GO:0005789 (located in) endoplasmic reticulum membrane GO:0005796 (located in) Golgi lumen GO:0005886 (located in) plasma membrane GO:0031093 (located in) platelet alpha granule lumen GO:0070062 (located in) extracellular exosome GO:0072562 (located in) blood microparticle

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|P07225|PROS_HUMAN Vitamin K-dependent protein S OS=Homo sapiens OX=9606 GN=PROS1 PE=1 SV=1 MRVLGGRCGALLACLLLVLPVSEANFLSKQQASQVLVRKRRANSLLEETKQGNLERECIE ELCNKEEAREVFENDPETDYFYPKYLVCLRSFQTGLFTAARQSTNAYPDLRSCVNAIPDQ CSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPG SYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKS CEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPLNLDTKYELL YLAEQFAGVVLYLKFRLPEISRFSAEFDFRTYDSEGVILYAESIDHSAWLLIALRGGKIE VQLKNEHTSKITTGGDVINNGLWNMVSVEELEHSISIKIAKEAVMDINKPGPLFKPENGL LETKVYFAGFPRKVESELIKPINPRLDGCIRSWNLMKQGASGIKEIIQEKQNKHCLVTVE KGSYYPGSGIAQFHIDYNNVSSAEGWHVNVTLNIRPSTGTGVMLALVSGNNTVPFAVSLV DSTSEKSQDILLSVENTVIYRIQALSLCSDQQSHLEFRVNRNNLELSTPLKIETISHEDL QRQLAVLDKAMKAKVATYLGGLPDVPFSATPVNAFYNGCMEVNINGVQLDLDEAISKHND IRAHSCPSVWKKTKNS >tr|F1QK29|F1QK29_DANRE Vitamin K-dependent protein S OS=Danio rerio OX=7955 GN=pros1 PE=4 SV=1 MRSLKAACSGSELGLLLLLLSATLCGSQRFLPQSKASEFLLRHRRANTLFEESKKGNLER ECIEELCNKEEAREIFENNLETEYFYPRYVVCLGSHRVGINNPEPGIPQNLRTCVEEISN QCLPPPCYKEGSERCVDGQGSYRCVCKPGWRGQRCEQDIDECEDPEFPAGCSQTCFNLPG SFTCGCESGYYTNDGVHCIDIDECVLFPSVCVEPSKCINAPGTFECRCQLGYTYNMSSHT CVDVDECLEDACAGECVNAVGSFSCQCDGRRGLQLDEDGLGCVSIPQCLQLYDHKHKEML YLGEQFSGLPVIYLRFRLQPHTRFAAEFDFRTFDPEGVILYAESSPDSWIMLGLRSGRIE VQFKNEHSIKMTSGGKAINDGQWHVISVEELSGSISVKISKEAVMSINSPERLFTPVNDK LETKVYIAGLPNHNQSLIKTINPRLDGCIRGWNLMNQGASGVKEVIQEKESKHCYVHVEK GSFFSGGGHALFNIDYSVSGQWKLDVVMSLRPSSTTGVILALVSNNTVPLLVAVVSLGPD DAELQVLLDGVCVATLQSLMLCYPDRLVVELRASAEGLQISANSSSVSYSEPQTLSAALH KLDTAMHTQPQTYIGGLPDLPLSITPVSAFYHGCLELVIGGRQLDFDEAVSKDNSIKSHS CPPYSITQSPSAP
Selected proteins from model organisms >sp|P07225|PROS_HUMAN Vitamin K-dependent protein S OS=Homo sapiens OX=9606 GN=PROS1 PE=1 SV=1 MRVLGGRCGALLACLLLVLPVSEANFLSKQQASQVLVRKRRANSLLEETKQGNLERECIE ELCNKEEAREVFENDPETDYFYPKYLVCLRSFQTGLFTAARQSTNAYPDLRSCVNAIPDQ CSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPG SYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKS CEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPLNLDTKYELL YLAEQFAGVVLYLKFRLPEISRFSAEFDFRTYDSEGVILYAESIDHSAWLLIALRGGKIE VQLKNEHTSKITTGGDVINNGLWNMVSVEELEHSISIKIAKEAVMDINKPGPLFKPENGL LETKVYFAGFPRKVESELIKPINPRLDGCIRSWNLMKQGASGIKEIIQEKQNKHCLVTVE KGSYYPGSGIAQFHIDYNNVSSAEGWHVNVTLNIRPSTGTGVMLALVSGNNTVPFAVSLV DSTSEKSQDILLSVENTVIYRIQALSLCSDQQSHLEFRVNRNNLELSTPLKIETISHEDL QRQLAVLDKAMKAKVATYLGGLPDVPFSATPVNAFYNGCMEVNINGVQLDLDEAISKHND IRAHSCPSVWKKTKNS >tr|F1QK29|F1QK29_DANRE Vitamin K-dependent protein S OS=Danio rerio OX=7955 GN=pros1 PE=4 SV=1 MRSLKAACSGSELGLLLLLLSATLCGSQRFLPQSKASEFLLRHRRANTLFEESKKGNLER ECIEELCNKEEAREIFENNLETEYFYPRYVVCLGSHRVGINNPEPGIPQNLRTCVEEISN QCLPPPCYKEGSERCVDGQGSYRCVCKPGWRGQRCEQDIDECEDPEFPAGCSQTCFNLPG SFTCGCESGYYTNDGVHCIDIDECVLFPSVCVEPSKCINAPGTFECRCQLGYTYNMSSHT CVDVDECLEDACAGECVNAVGSFSCQCDGRRGLQLDEDGLGCVSIPQCLQLYDHKHKEML YLGEQFSGLPVIYLRFRLQPHTRFAAEFDFRTFDPEGVILYAESSPDSWIMLGLRSGRIE VQFKNEHSIKMTSGGKAINDGQWHVISVEELSGSISVKISKEAVMSINSPERLFTPVNDK LETKVYIAGLPNHNQSLIKTINPRLDGCIRGWNLMNQGASGVKEVIQEKESKHCYVHVEK GSFFSGGGHALFNIDYSVSGQWKLDVVMSLRPSSTTGVILALVSNNTVPLLVAVVSLGPD DAELQVLLDGVCVATLQSLMLCYPDRLVVELRASAEGLQISANSSSVSYSEPQTLSAALH KLDTAMHTQPQTYIGGLPDLPLSITPVSAFYHGCLELVIGGRQLDFDEAVSKDNSIKSHS CPPYSITQSPSAP >NP_035303.1 vitamin K-dependent protein S preproprotein [Mus musculus] MRVLSARFRVLLACLALVIPVSETNFLSKERASQVLVRKRRANTLFEETMKGNLERECIEELCNKEEARE VFENNPETDYFYPKYLGCLGAFRVGSFHAARQSANAYPDLRSCVKAISDQCDPIPCNEDGYLACQDGQAA FTCFCKPGWQGDRCQYDVNECKDPSNVNGGCSQICDNTPGSYHCSCKRGFAMLPNKKDCKDLDECALKPS VCGTAVCKNIPGDFECECPDGYRYDPSSKSCKDVDECSENMCAQLCVNFPGGYSCYCDGKKGFKLAQDQK SCEGIPVCLSLDLDKNYELLYLAEQFAGVVLYLKFRLPDITRFSAEFDFRTYDSEGIILYAESLDHSNWL LIALRDGKIEVQFKNEFSTQITTGGNVINNGIWNMVSVEELDDSVSIKIAKEAVMNINKLGSLFKPTDGF LDTKIYFAGLPRKVESALIKPINPRLDGCIRGWNLMKQGALGAKEIIEGKQNKHCFLNVEKGSYYPGSGI AQFSIDYNNVTNAEGWQMNVTLNIRPSTGTGVMLALVSGGTVPFALSLVDSRSGTSQDIVVFVENSVVAR LEAVSLCSDQQSQLKCNVNRNGLELWTPLRKDVIYSKDLQRQLAVLDKAMKRTVATYLGGIPDISFSATP VNAFYSGCMEVNINGVQLDLDEAISKHKDIRAHSCPSVRKIQKNF >NP_112348.2 vitamin K-dependent protein S precursor [Rattus norvegicus] MRVLSVRFRVLLACLALVLPVSETNFLSKERASQVLVRKRRANTLLEETKKGNLERECIEELCNKEEARE VFENNPETDYFYPKYLGCLGAFRVGAFSAARQSANAYPDLRSCVNAIPDQCDPMPCNEDGYLSCKDGQGA FTCICKPGWQGDKCQFDINECKDPSNINGGCSQTCDNTPGSYHCSCKIGFAMLTNKKDCKDVDECSLKPS VCGTAVCKNIPGDFECECPNGYRYDPSSKSCKDVDECSENTCAQLCVNYPGGYSCYCDGKKGFKLAQDQR SCEGIPVCLSLDLDKNYELLYLAEQFAGVVLYLKFRLPDITRFSAEFDFRTYDSEGIILYAESLDHSNWL LIALREGKIEVQFKNEFSTQITTGGNVINNGIWNMVSVEELDDSVSIKIAKEAVMNINKLGSLFKPTDGF LDTKIYFAGLPRKVESALIKPINPRLDGCIRGWNLMKQGALGAKEIVEGKQNKHCFLTVEKGSYYPGSGI AQFSIDYNNVTNAEGWQINVTLNIRPSTGTGVMLALVSGDTVPFALSLVDSGSGTSQDILVFVENSVAAH LEAITLCSEQPSQLKCNINRNGLELWTPVRKDVIYSKDLQRQLAILDKTMKGTVATYLGGVPDISFSATP VNAFYSGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVRKIQKNF >NP_776863.1 vitamin K-dependent protein S precursor [Bos taurus] MRVLGGRTGTLLACLALVLPVLEANFLSRQHASQVLIRRRRANTLLEETKKGNLERECIEELCNKEEARE IFENNPETEYFYPKYLGCLGSFRAGLFTAARLSTNAYPDLRSCVNAISDQCNPLPCNEDGFMTCKDGQAT FTCICKSGWQGEKCESDINECKDPVNINGGCSQICENTPGSYHCSCKNGFVMLSNKKDCKDVDECVLKPS ICGTAVCKNIPGDFECECAEGYKYNPVSKSCDDVDECAENLCAQLCVNYPGGYSCYCDGKKGFKLAQDQK SCEAVPVCLPLDLDKNYELLYLAEQFVGVVLYLKFRLPETTRFSAEFDFRTYDSEGVILYAESSDHSAWF LIALREGKIEIQFKNEKTTKMTTGGKVINDGLWHMVSVEELEQSISVKIAKEAVMNINKPGSLFKPTNGF LETKVYFAGVPRKMENALIRPINPRLDGCIRGWNLMNQGTSGVKEIIQEKQNKHCLVNVEKGSYYPGTGV AQFSINYKNESNPEAWQINVSLNIRPSAGTGVMLALVSDNTVPFALSLVDSATEKLQDILVSVESMVIGR IEAISLCSDQQTFLEIRVNRNNLELSTQLRKDSFHSEDFQRQFAILDEAMKGTVVTYLGGLPDVPFSATP VNAFYQGCMEVNINGVQVDLDEAISKHNDIRAHSCPSVWQKTKHT >XP_020926395.1 vitamin K-dependent protein S [Sus scrofa] MRVLGGRCGALLACLALALPVLEANFLSKQHASQVLIRKRRANSMLEERKQGNLERECIEELCSKEEARE VFENDPETEYFYPAYLACLGSFRAGLFTAARLSTNAYPDLRSCVNAIPDQCNPLPCNEDGYLTCKDGQAM FTCICKSGWEGEKCELDINECKDPANINGGCSQICDNTPGSYHCSCKSGFIMLSNKKDCKDVDECSVKPS ICGTAVCKNIPGDFECECPEGYRYNPTLKYCEDVDECSENMCAQLCVNYPGGYSCYCDGKRGFKLAQDQK SCEAVPVCLPLNLDKNYELLYLAEQFVGVVLYLKFRLPEITRFSAEFDFRTYDSEGVILYAESSDHSAWF LIALRDGKIEIQFKNEHTTKITTGGRVINDGLWNMVSVEELEQSISVKIAKEAVMNINKPESLFKPTNGF LETKVYFAGLPRKVENALIKPINPRLDGCIRGWNLMNQGASGVKEIIQEKQNKHCLVTVEKGSYYPGSGV AQFSIDYKNVSSAGAWQVNVSLNIRPSAGTGVMLALVSGNTVPFALSLVDSATEKLQDIVVSVENVEIAR IKALSLCSSLQSLLEMRVSVNSLELLTQFEKRRISSEDYQGQFAILDKAMEGTVATYLGGLPDVPFSATP VNAFYNGCMDVIINGVPLDLDEAIAKHNDIRAHSCPSVWKNTRNT >XP_043304830.1 vitamin K-dependent protein S [Cervus canadensis] MRVPGGRTGTLLACLALVLPVLEANFLSRQHASQVLVRRRRANTLLEETKKGNLERECIEELCNKEEAREVFENNPETEY FYPKYLGCLGSFRAGLFTTARLSTNTYPDLRSCVNAIPDQCNPLPCNEDGYLSCKDGQATFTCICKSGWQGEKCESDINE CKDPANVNAGCSQICVNTPGSYHCSCKNGFVMLSNKKDCKDVDECVLKPSICGTAVCKNIPGDFECECAEGYKYNPVSKS CDDVDECSENLCAQLCVNYPGGYSCYCDGKKGFKLAQDQKSCEAVPVCLPLDLDKNYELLYLAEQFVGVVLYLKFRLPET TRFSAEFDFRTYDSEGVILYAESSDHSAWFLIALREGKIEIQFKNENTVKMTTGGKVINDGLWNMVSVEELEQSISVKIA KEAVMNINKPESLFKPTNGFLETKVYFAGIPRKLENALIRPINPRLDGCIRGWNLMNQGTSGVKEIIQEKQNKHCLVTVE RGSYYPGTGVAQFSIDYKNESNPEAWQINVSLNIRPSAGTGVMLALVSGDTVPFALCLVDSATEKLQDILVSVESMVIAR IQAISLCSDQQTFLEIRVNRNNLELLTQLTKDSFHSEDFQRQFAILDEAMKGTVATYLGGLPDVPFSATPVNAFYQGCME VNINGVQLDLDEAISKHNDIRAHSCPSVWQKTKHT >KAB0344409.1 hypothetical protein FD754_021335 [Muntiacus muntjak] MFAYCFVYILFTVFILFLTLHTWLLYFQPTLQETQEMAVLSRQHASQVLVRRRRANSLLEETKKGNLERECIEELCNKEE AREVFENNPETEYFYPKYLGCLGSFRAGLFTTARLSTNTYPDLRSCVNAIPDQCNPLPCNEDGYLSCKDGQATFTCICKS GWQGEKCESDINECKDPANVNGGCSQICVNTPGSYHCSCKNGFVMLSNKKDCKDVDECVLKPSICGTAVCKNIPGDFECE CAEGYKYNPVSKSCDDVDECSENLCAQLCVNYPGGYSCYCDGKKGFKLAQDQKSCEAVPVCLPLDLDKNYELLYLAEQFV GVVLYLKFRLPETTRFSAEFDFRTYDSEGVILYAESSDHSAWFLIALREGKIEIQFKNENTVKMTTGGKVINDGLWNMVS VEELEQSISVKIAKEAVMNINKPESLFKPTNGFLETKVYFAGIPRKLENALIRPINPRLDGCIRGWNLMNQGTSGVKEII QEKQNKHCLVTVERGSYYPGTGVAQFSIDYKNESNPEAWQINVSLNIRPSAGTGVMLALVSGDTVPFALSLVDSATEKLQ DILVSVESMVIARIQAISLCSDQQTFLEIRVNRNNLELLTQLTKDSFHSEDFQRQFAILDEAMKGTVATYLGGLPDVPFS ATPVNAFYQGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVWQKTKHT >KAF4025963.1 hypothetical protein G4228_018124 [Cervus hanglu yarkandensis] MRVPGGRTGTLLACLALVLPVLEANFLSRQHASQVLVRRRRANTLLEETKKGNLERECIEELCNKEEAREVFENNPETEY FYPKYLAIPDQCNPLPCNEDGYLSCKDGQATFTCICKSGWQGEKCESDINECKDPANVNAGCSQICVNTPGSYHCSCKNG FVMLSNKKDCKDVDECVLKPSICGTAVCKNIPGDFECECAEGYKYNPVSKSCDDVDECSENLCAQLCVNYPGGYSCYCDG KKGFKLAQDQKSCEAVPVCLPLDLDKNYELLYLAEQFVGVVLYLKFRLPETTRFSAEFDFRTYDSEGVILYAESSDHSAW FLIALREGKIEIQFKNENTVKMTTGGKVINDGLWNMVSVEELEQSISVKIAKEAVMNINKPESLFKPTNGFLETKVYFAG IPRKLENALIRPINPRLDGCIRGWNLMNQGTSGVKEIIQEKQNKHCLVTVERGSYYPGTGVAQFSIDYKNESNPEAWQIN VSLNIRPSAGTGVMLALVSGDTVPFALSLVDSATEKLQDILVSVESMVIARIQAISLCSDQQTFLEIRVNRNNLELLTQL TKDSFHSEDFQRQFAILDEAMKGTVATYLGGLPDVPFSATPVNAFYQGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVW QKTKHT >XP_018104341.1 vitamin K-dependent protein S isoform X2 [Xenopus laevis] MGLLDKVCLVLLASTLLAVTLAEGLTFLSPQHASQFLSRRRRANSFLEESKGGNLERECIEELCNKEEAREIFENVPETE YFFPKYLACLGAHRSGTLSKLSYLNFDGPVDLRACVNAIPDQCTPLPCNKERSKECIDGKGNFTCICKPGFQGPLCDEDI NECVDPVNPNAGCNQKCLNLPGSYRCACEDGYYMLPNKHTCSDRNECEMFPTICGSAVCKNTPGKYECECDNGYRYNSSA KACEDIDECAVRSCSQICVNNPGGYTCYCDGRRKYKLAQDKTSCESIPVCVPLNLETNYELLFLAEQFTGIPVVYLRFKL PDVSRFSAEFDFRTYDGEGVILYAESADSTSWFLLALRDGKIEIQFKNELWTKVTTGGKAINNGEWHIITVEELENIISV KIAKEAVMNINNPRSLFKSSNGILEIKVYIAGLPRKVDNIIKPINPRLDGCIRGWNLMNQGALGVKEVIQGKQSKHCLVT VERGSYYPGGGVARFIMNYNVSTNDEWVANITFNIRSSTGIGVMFSLVNGETVPLAIAIEDLGSDFLQGIVVSIHSATVA RLTTKRICTDKNLLISVSITKNTLVLNANSYTDITYASQVELDKQLSILDQAMQENPDTYLGGIPDIPVAATPVSAHYVG CMDVTINNELMDLDGAVSKQNDIRSHSCPLIL >OWK00463.1 PROS1 [Cervus elaphus hippelaphus] MVGQVLSRQHASQVLVRRRRANTLLEETKKGNLERECIEELCNKEEAREVFENNPETEYFYPKYLGCLGSFRAGLFTTAR LSTNTYPDLRSCVNAIPDQCNPLPCNEDGYLSCKDGQATFTCICKSGWQGEKCESDINECKDPANVNAGCSQICVNTPGS YHCSCKNGFVMLSNKKDCKDVDECVLKPSICGTAVCKNIPGDFECECAEGYKYNPVSKSCDDVDECSENLCAQLCVNYPG GYSCYCDGKKGFKLAQDQKSCEAVPVCLPLDLDKNYELLYLAEQFVGVVLYLKFRLPETTRLSLCPLFRFSAEFDFRTYD SEGVILYAESSDHSAWFLIALREGKIEIQFKNENTVKMTTGGKVINDGLWNMDILVSVESMSVLWQRKQIHGCHSGLAST VGKSLNTDAQSEAEAQVRKLEEQRLEKDVWVSTALLTLRWQTRNWLWVCLHFDWRQTKMKSEVVLNHIIILMGINFKFVQ KMNLNKVKFTSLQKKACSDSWKPEFTHVPTLLSHNSEDFCSVFPDSCYLCSTFQEACLPNDSSFWVKQKGRWEQCSDAVS SQGLCSFPPYL >XP_416641.3 vitamin K-dependent protein S [Gallus gallus] MRPRGGRCVPLLAGLAVALALAEAATFLSHQYASEFLARKRRANSFMEESKKGNLERECVEELCNKEEAR EIFENNPETEYFYPKYLSCLASYRAGVFRVPTVTPDSPANLRVCVSEISNQCSPLPCHRDGYKECIDGQA KYTCICKPGWQGENCEEDINECEDINGGCSQRCSNLPGSYRCLCEDGYFMHSNKRDCRDINECALHPNIC GTAVCKNTLGKYECECAEGYKYNSTSKSCEDIDECAENTCAQLCVNSPGSYSCYCDGKKGFKLSKDMKNC ESVPVCIPLNLERNYELLYLAEHFTGIYVLYLKFKLPNVTRFSAEFDFRTYDSEGIILYAESFDNTAWIL LALRDGKIEIQFKNEFGTKVTSGGKAINDGLWHIISVEELENSISVKIAKEAVMNINSPGTLFKQSHGFL ETKVYIAGLPDKVGDTLIKQINPRLDGCIRAWNLMNQGHSGVKEVIQEKQSKHCLVTVERGSFYPGTGMA QFDINYNNRDSAEDWLINVTMTIRPSTDTGVMFALVSNETVPLALSIVDSNSSDSQEIIVTIGNITVARL ESKKLCTPRKVQVGLLVTKQQLQLSVDSRTDQSNSEQLSVLHQAMMTNVVTYLGGLPDVPLGATLVTAFY NGCMEVKVNSRQLDLDEAISKHNSIRSHSCPLIME >XP_516603.3 vitamin K-dependent protein S [Pan troglodytes] MRVLGGRCGALLACLLLVLPVSEANFLSKQQASQILVRKRRANSLLEETKQGNLERECIEELCNKEEARE VFENDPETDYFYPKYLVCLRSFQTGLFTAARQSTNAYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKAS FTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNTPGSYHCSCKSGFVMLSNKKDCKDVDECSLKPS ICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQK SCEVVSVCLPLNLNTKYELLYLAEQFAGVVLYLKFRLPEISRFSAEFDFRTYDSEGVILYAESIDHSAWL LIALRGGKIEVQLKNEHTSKITTGGDVINNGLWNMVSVEELEHSISIKIAKEAVMDINKPGPLFKPENGL LETKVYFAGFPRKVESELIKPINPRLDGCIRSWNLMKQGASGIKEIIQEKQNKHCLVTVEKGSYYPGSGI AQFHIDYNNVSGAEGWHVNVTLNIRPSTGTGVMLALVSGNNTVPFAVSLVDSTSEKSQDILLSVENTVIY RIQALSLCSDQQSHLEFRVNRNNLELSTPLKIETISHEDLQRQLAVLDKAMKAKVATYLGGLPDVPFSAT PVNAFYNGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVWKKTKNS >XP_038300575.1 vitamin K-dependent protein S isoform X1 [Canis lupus familiaris] MRLLAGRCGALLACLVLVLPVSEANFLSKEHASQVLVRKRRANSMFEETKKGNLERECIEELCNKEEARE IFENDPETDYFYPKYLGCLGSFRAGLFTAARLSTDAYPDLRSCVTAIPDQCSPLPCNEDGYKTCRDGQAT FTCICKPGWQGDRCEYDINECKDPSNINGGCSQMCDNTPGSYHCSCKSGFVMLLNKKDCKDVDECSIMPD ICGAAVCKNIPGDYECECAEGYRYNPALKSCEDVDECSENLCAQLCVNYPGGYSCYCDGRKGFKLAQDHK SCEAVPVCLPLNLDKNYELLYLAEQFVGVVLYLKFRLPEITRFSAEFDFRTYDSEGVILYAESLDRSAWF LIALRDGKIEIQFKNEFTTKITTGGKAINNGLWNTVSVEELEYSISIKIAKEAVMNINKPGRLFKPSNGF LETKVYFAGLPRKVENVLIRPINPRLDGCIRGWNLMNQGASGVKEIIQEKQNKHCLVTVEKGSYYPGSGV AVFGIDYTPDSDSAAGAWQLNASLSVRASAGTGVLLALVSGSSVPLALSLADSISETLQDILVSVENIVI SRIEAVNLCSNQQVHLELKVNRNNLELSTPVKKDTISSEDLPQQFASLDKAMKGTVTTYLGGLPDIPFGA TPVNVFYNGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVLKSTKNS >XP_002716802.1 PREDICTED: vitamin K-dependent protein S [Oryctolagus cuniculus] MRVLGGRCGALLACLALVLPVSEANFLTKQHASQVLVRKRRANSMLEETKKGNLERECIEELCNKEEARE VFENDPETDYFYPKYLGCLGSFRAKLFTATRRSANPYPDLRSCVNAIPDQCNPLPCSEEGYLNCKDGQAT FTCICKPGWQGEKCEIDINECKDPTNINGGCSQICDNTAGSYHCSCKSGFVMLANEKDCKDMDECSVKPS VCGTAVCKNTPGDFECECSEGYRYNPTAKSCEDIDECSENMCAQLCVNYPGGYSCYCDGKKGFKLAQDKK SCEAVPVCLPLDLDKNYQLLYLAEQFVGAVLYLKFHLPEITRFSAEFDFRTYDSEGVILYAESLDHSTWF LIALRQGKIEIQFKNDYAAQITTGGQVINDGLWNMVSVEELEHSVSIKIAQEPVMNINKPGSLFKPTNGF LETKVYFAGLPRKVENALIRPINPRLDGCMRGWNLMKQGASGVKEIIQQKQKKHCLVTVEKGSYYPGSGI AQFHIDYNNLSYVEDWQVNVTLKIRPSTGTGVMLALVSGNTVPFALSLVQSTSETSQDILVSVENRVIYQ LESISLCSGQQSQLEFSVSRNHLELSTPLVKDVIYSEDLQRHLAVLDEAMKGTVTTYLGGLPDVPFNATP VNAFYNGCMEVNINGVQLDLDEAVSKHNDIRAHSCPSVWNDKTNS >XP_024100978.1 vitamin K-dependent protein S isoform X1 [Pongo abelii] MRVPGGRCWALLACLLLVLPVSEANFCLYFRNDFIYNRTCISVLVGLSGCNFFYSICFLSKQQASQVLVR KRRANSLLEETKQGNLERECIEELCNKEEAREVFENDPETDYFYPKYLVCLRSFQTGLFTAARQSTNAYP DLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNT PGSYHCSCKSGFVMLSNKKDCKDVDECSLKISVCGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS ESMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPLNLDTKYELLYLAEQFAGVVLYLKFRLP EISRFSAEFDFRTYDSEGVILYAESIDHSAWLLIALRGGKIEVQLKNEHTSKITTGGDVINNGLWNMVSV EELEHSISIKIAKEAVMDINKPGPLFKPENGLLETKVYFAGFPRKVESELIKPINPRLDGCIRSWNLMKQ GASGIKEIIQEKQNKHCLVTVEKGSYYPGSGIAQFHIDYNNVSSAEGWHINVTLNIRPSMGTGVMLALVS GNSTVPFAVSLVDSTSEKSQDILLSVENTVIYRIQALSLCSDQQSHLEFRVNRNNLELSTPLKIETISHE DLQRQLAVLDKAMKAKVATYLGGLPDVPFSATPVNAFYNGCMEVNINGVQLDLDEAISKHNDIRAHSCPS VWKKTKNS >XP_019475114.1 vitamin K-dependent protein S [Meleagris gallopavo] MEESKKGNLERECIEELCNKEEAREIFENNPETEYFYPKYLSCLASYRAGVFRVTAVTPDSPADLRACVN EISNQCSPLPCHRDGYKDCIDGQARYTCICKPGWQGENCEKDINECEDFNGGCSQRCSNLPGSYRCLCED GYFMHSNKRDCRDINECALHPNICGTAVCKNTLGKYECECAEGYTYNSTSKNCEDIDECAENTCAQLCVN SPGSYSCYCDGKKGFKLSKDMKNCESISACIPLNLERNYELLYLAEQFTGIPVLYLKFKLPNVTRFSAEF DFRTYDSEGVILYAESLDNTAWILLALRDGKIEIQFKNEFGTKVTSGGKAINDGLWHIISVEELENSISV KIAKEAVMNINSPGTLFKQSHGFLETKVYIAGLPRKVGDSLIKQINPRLDGCIRAWNLMNQGHSGVKEVI QEKQSKHCLVTVERGSFYPGTGMAKFHINYNNLDSAEDWLINVTMTIRPSTDTGVMFALVSNETVPLALS IVDSNSSDSQEIIVTIGNITVASLESKKLCTPRKVQVGLLVTKQQLQLSVDSRTDQSNSEQLSVLHQAMM TNVVTYLGGLPDVPLGATLVTAFYNGCMEVKVNSRQLDLDEAILKHNSIRSHSCPLIME >XP_034812860.1 vitamin K-dependent protein S isoform X1 [Pan paniscus] MRVLGGRCGALLACLLLVLPVSEANFCLYFRNDFIYNRACISVLVSLSGCNFFYSICFLSKQQASQILVR KRRANSLLEETKQGNLERECIEELCNKEEAREVFENDPETDYFYPKYLVCLRSFQTGLFTAARQSTNAYP DLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKCEFDINECKDPSNINGGCSQICDNT PGSYHCSCKSGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECS ENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPLNLDTKYELLYLAEQFAGVVLYLKFRLP EISRFSAEFDFRTYDSEGVILYAESIDHSAWLLIALRGGKIEVQLKNEHTSKITTGGDVINNGLWNMVSV EELEHSISIKIAKEAVMDINKPGPLFKPENGLLETKVYFAGFPRKVESELIKPINPRLDGCIRSWNLMKQ GASGIKEIIQEKQNKHCLVTVEKGSYYPGSGIAQFHIDYNNVSSAEGWHVNVTLNIRPSTGTGVMLALVS GNNTVPFAVSLVDSTSEKSQDILLSVENTVIYRIQALSLCSDQQSHLEFRVNRNNLELSTPLKIETISHE DLQRQLAVLDKAMKAKVATYLGGLPDVPFSATPVNAFYNGCMEVNINGVQLDLDEAISKHNDIRAHSCPS VWKKTKNS >XP_023094643.1 vitamin K-dependent protein S isoform X1 [Felis catus] MPSMAFQLLNESRPSSLLIQMFPGLSFICTTVLSKQHASQVLIRKRRANSMFEETKKGNLERECIEELCN KEEAREIFENNPETDYFYPKYLDCLGSFRAGLFTAARQSTDAYPDLRSCVTAIPDQCSPLPCNEDGYMSC KDGQATFTCVCKSGWQGDKCEYDINECKDPSNVNGGCSQICDNTPGSYHCSCKSGFVMLSNKKDCKDVDE CSMKPDICGTAVCKNIPGDFECECAEGYRYNPTLKSCEDVDECSENMCAQLCVNYPGGYSCYCDGKKGFK LAQDHRSCEAVPVCLPLNLDKNYELLYLAEQFVGVVLYLKFRLPEITRFSAEFDFRTYDSEGVILYAESL DHSCWFLIALRDGKIEIQFKNEYATKITTGGKVINNGLWNTVSVEELEYSISVKIAKEAVMNINKPRSLF KPANGFLETKVYFAGLPRKGENVLIKPINPRLDGCIRGWNLMNQGASGVKEIIQEKQNKHCLVTVEKGSY YPGSGVALFSIDYNNISNAEGWQVNVSLNIRPSAGTGVMFALVSGYTVPFALSLVDSASEKLQDILVSVE NMVVSRVEAISLCSNEQFHLEVRVNRTSLELLTPLKKDIIYSEDLQSQLAILDIAMKERVSTYLGGLPDI PFSATPVNAFYNGCMEMSINGVQLDLDEAISKHNDIRAHSCPSVLKKTKNS >XP_004002896.2 vitamin K-dependent protein S [Ovis aries] MRVLGGLTGTLLTCLALVLPVLEANFLSRQHASQVLVRRRRANSLLEETKKGNLERECIEELCNKEEARE VFENNPETEYFYPKYLGCLGSFRAGLFTTARLSTNAYPDLRSCVNAIPDQCNPLPCNEDGYMTCKDGQAT FTCICKSGWQGEKCESDINECKDPVNVNGGCSQICENTPGSYHCSCKNGFIMLSNKKDCKDVDECVLKPS ICGTAVCKNIPGDFECECAEGYKYNPVSKSCDDVDECSENLCAQLCVNYPGGYSCYCDGKKGFKLAQDQK SCEAVPVCLPLNLEKNYELLYLAEQFVGVVLYLKFRLPETTRFSAEFDFRTYDSEGVILYAESSDHSSWF LIALREGKIEIQFKNEKTVKMTTGGKVINDGLWNMVSVEELEQSISVKIAKEAVMNINKPESLFKPTNGF LETKVYFAGVPRKVENALIRPINPRLDGCIRGWNLMNQGTSGVKEIIQEKQNKHCLITVERGSYYPGTGV AQFSIDYKNESNPEAWQINVSLNIRPSAGTGVMLALVSGNTVPFALSLVDSATEKLQDILVSVESMVIAR IEAETLCSDQQTFLEIRVNRNNLELLTQLRKDSFHSEDFQRQFAILDEAMKGTVATYLGGLPDVPFSATP VNAFYQGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVWQNTEHT >XP_030865634.1 vitamin K-dependent protein S [Gorilla gorilla gorilla] MRVQGGRCGALLACLLLVLPLSEANFFSKQQASQVLVRKRRANSLLEETKQGNLERECIEELCNKEEARE VFENDPETDYFYPKYLVCLRSFQTGLFTAARQSTNAYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKAS FTCTCKPGWQGEKCEFDINECKDPPNINGGCSQICDNIPGSYHCSCKSGFVMLSNKKDCKDVDECSLKPS ICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQK SCEVVSVCLPLNLDTKYELLYLAEQFAGVVLYLKFRLPEISRFSAEFDFRTYDSEGVILYAESVDHSAWL LIALRGGKIEVQLKNEHTSKITTGGDVINNGLWNMVSVEELEHSISIKIAKEAVMDINKPGPLFKPENGL LETKVYFAGFPQKVESELIKPINPRLDGCIRSWNLMKQGASGIKEIIQEKQNKHCLVTVEKGSYYPGSGI AQFHIDYNNVSSAEGWHVNVTLNIRPSTGTGVMLALVSGNNTVPFAVSLVDSTSEKSQDILLSVENTVIY RIQAPSLCSDQQSHLEFRVNRNNLELSTPLKIETISHEDLQRQLAVLDKAMKAKVATYLGGLPDVPFSAT PVNAFYNGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVWKKTKNS >XP_011488632.1 vitamin K-dependent protein S isoform X1 [Oryzias latipes] MPVPRRILGRALAFFVLLVTFADAHRFLSQNTASQFLRRHRRANSGFEETKAGNLERECIEELCNKEEAR EIFENQPETEYFYPKYVVCLGSHRVGISNGNSGSDIPSNLRTCVKEISNQCTPFPCYKEGSEGCVDGQAS FTCVCKPGWKGRLCEYDIDECSDPDFPAGCKHKCNNIPGSFYCMCDEGYFLNDKINCVDINECLLYRSIC EEPAKCVNTPGMYECQCPPGFKYNFTSKSCDDVNECERVLCDGTCVNTVGSYTCICDGRAGLRLAVDDRY CETIPICVDLNDYKHPEMLYLGELFAGRPVILLHFRLPENTKFAAEFDFRTFDPEGVILYAESSNHSWFM LGLRGGRIEVQFKNHHAFKVTSGGKFINDGEWHVISVDELENSISVKISNEAVMSINSPESLFTSVNGKL ETKVYIAGLPNRTNNVIKPINPRLDGCIRGWNFMKQGPSGVKEIIQGKQSKHCFVHVERGSFFSGEGLAH FDIDYTGKSGKWNVNVEMRIRPSKSTGVLFALVYNNTVPLSVAVVEKGEGDANLQVFLEGVSVATLDSLM LCYPERLGIQLNVTPSEIQLSASSSTVSYIKSDVLEKKLEVLNITMQNPVGTYIGGIPGNIPLIATPVSA FYYGCMEITINDQWLDFDEAHRKHNSIKSHSCPPVSASEPHPIVSHLHR >XP_021143422.1 vitamin K-dependent protein S isoform X1 [Columba livia] MSSTAETTVLSQQYASQFLVRKRRANSFMEESKKGNLERECIEELCNKEEAREIFENNPETEYFYPKYLS CLASHRAGVFRVTAVTPDSPDDLRVCVNEISNQCSPLPCHKDGYKDCIDGQAKYTCICKPGWQGEKCEED INECEDLNGGCSQRCSNLPGSYRCLCEDGYFMHSNKRDCGDINECVLNPNICGTATCKNTLGKYECECAE GYMYNPTSKNCEDIDECAENVCAQLCVNSPGSYSCYCDGKKGFKLSKDMKNCESVTACIPLNLEKNYELL YLAEQFIGIPVLYLKFKLPNITRFMAEFDFRTYDAEGVILYAESLDNTAWILLALRDGKIEIQYKNEFGT KVTSGGKAINDGLWHIISVEELEHSISVKIAKEAVMSINSPGTLFKQSQGFLETKVYIAGLPRKVGNTLV KQINPRLDGCIRAWNLMNQGHSGVKEVIQEKQSKHCLVAVERGSFYPGTGMAKFQINYNNLDSAEDWLIN VTMTIRPSTDTGVMFALVSNETVPLALSIVDSNSSDSQKIIVTIGNTTVAQLESKKLCTPRKVMVGLLVT KEQLELSVDSHTDRSNSEKLSVLHQAIMANVVTYLGGLPDVPLGATLVTAFYNGCMEVKINNRELDLDEA ISKHNDIRSHSCPLIMQ >XP_005674861.1 PREDICTED: vitamin K-dependent protein S [Capra hircus] MRVLGGLTGTLLTCLALVLPVLEANFLSRQHASQVLVRRRRANSLLEETKKGNLERECIEELCNKEEARE VFENNPETEYFYPKYLGCLGSFRAGLFTTARLSTNAYPDLRSCVNAIPDQCNPLPCNEDGYMTCKDGQAT FTCICKSGWQGEKCESDINECKDPVNVNGGCSQICENTPGSYHCSCKNGFVMLSNKKDCKDVDECVLKPS ICGTAVCKNIPGDFECECAEGYKYNPISKSCDDVDECSENLCAQLCVNYPGGYSCYCDGKKGFKLAQDQK SCEAVPVCLPLNLEKNYELLYLAEQFVGVVLYLKFRLPETTRFSAEFDFRTYDSEGVILYAESSDHSSWF LIALREGKIEIQFKNEKTVKMTTGGKVINDGLWNMVSVEELEQSISVKIAKEAVMNINKPESLFKPTNGF LETKVYFAGVPRKVENALIRPINPRLDGCIRGWNLMNQGTSGVKEIIQEKQNKHCLITVERGSYYPGTGV AQFSIDYKNESNPEAWQINVSLNIRPSAGTGVMLALVSSNTVPFALSLVDSATEKLQDILVSVESMVIAR IEAESLCSDQQTFLEIRVNRNNLELLTQLRKDSFHSEDFQRQFAILDEAMKGTVATYLGGLPDVPFSATP VNAFYQGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVWQNIEHT >XP_025070223.1 vitamin K-dependent protein S isoform X1 [Alligator sinensis] MCLVSTQLLWGHGQLMPPESGAAPAEAVLSQQHASEYLVRKRRANSFMEESKKGNLERECVEELCNKEEA REIFENDPETEYFYPKYIRCLTYTRLGISSVSVMSPDSSSDLRTCVTEISNQCTPLPCNENGYTKCIDGK AAYTCVCKQGWQGERCEEDIDECQDQENINGGCSQTCINLHGSYRCFCEDGYYMLPNKKDCRDWDECMLR PNICGTAKCQNTPGKYECVCAEGFRYNSTTKNCEDVDECAENICAQMCVNYKGSYACHCDGHKGFKLSQD MKTCEAVPVCLPLNLEPNYQLLYLAEQTTENAVLHLRFKLPNASRFSAEFDFRTYDNEGVILYAESSNNT GWFLLALRDGKIEIQFKNEHGTKVTSGGKAINDGVWQTISVEELEHSICVKIAREAVMSIKSPGNLFKQI NGSLEIKVYVAGLPPKVGNTLIKQINPRVDGCARALNLMSQGHLGLTEVIKKTQIKRCLPSVGKGSYYPG TGVAKFHINYNNDTNTGEWVINVALNIRPSKGTGVMFALVSGESVPLALSIVDSSSSNSQAIIVTIGNII IARLESKRFCTTRRTLVGFSASKQQIELSVDSQTDVTNSEQELSILDQAMRGTVAVYTYLGGLPDLPLGI TPLTVFYNGCMEAKVNSKELDLDQAAYKHSDIRSHSCPQVIGEDQFFK >XP_019331954.1 PREDICTED: vitamin K-dependent protein S [Alligator mississippiensis] MRPLAGGGCLLVLLALAEARVFLSQQHASEYLVRKRRANSFMEESKKGNLERECVEELCNKEEAREIFEN DPETEYFYPKYIRCLTYTRLGISSVSVMSPDSSSDLRTCVTDWDECMLRPNICGTAKCQNTPGKYECVCA EGFRYNSTTKNCEDVDECAENICAQMCVNYEGSYTCHCDGHKGFKLSQDMKTCEAVPVCLPLNLEPNYQL LYLAEQTTENAVLHLRFKLPNASRFSAEFDFRTYDNEGVILYAESSNNTGWFLLALRDGKIEIQFKNEHG TKVTSGGKAINDGVWQTISVEELEHSICVKIAREAVMSIKSPGNLFKQINGSLEIKVYVAGLPPKVGNTL IKQINPRIDGCARALNLMSQGHLGLTEVIKKTQIKRCLPSVGKGSYYPGTGVAKFHINYNNDTNTGEWVI NVALNIRPSKGTGVMFALVSGESVPLALSIVDSSSPNSQAIVVTVGNIIIARLESKRFCTTRRTLVGFSA SKQQIELTVDSQTDVTNSEQELSILDQAMRGAVAVYTYLGGLPDLPLGITPLTVFYNGCMEAKVNSKELD LDQAAYKHSDIRSHSCPQVIGEDQFFK >XP_015809320.1 PREDICTED: vitamin K-dependent protein S [Nothobranchius furzeri] MKRALGRPLACLMFLVTLLDADRFLSQNTASQFLSRHRRANTMFEESKKGNLERECIEELCNKEEAREIF ENQPETEYFYPRYVGCLGSHRVGINNQNSDSNIPSDLRTCVKGEKPHLRIWPISTNNSQDPFPNPKAQGS YPLIPRGEPQHTKLILKSISYKEVRMFENLLKCVYLADIDECSDPDFPAGCNQKCLNIPGSFHCMCEDGY FLNDNIHCVDVNECLLFPSICEKPAKCVNAPGMYECQCPLGFKYTSTSRTCDDVDECELGLCDDMCHNTI GSFTCHCDGRAGLRLAADERRCESIPVCVELNDYKHPEMLFLGEQFAGLPVIYLRFRLPESTKFAAEFDF RTFDPEGVVLYAESSQGSWFMLGLREGRIEVQFKNQHTSKVTSGGKAINDGQWHVISVDELKNSISVKIS KEAVMSINSPESLFTSVNGKLETKFYIAGLPNRTENIIKPINPRLDGCIRGWNLMNQGASGVKEVIQEKK SKHCFVHVERGSFFSGAGLAHFNVDYRDSGSWNVDLKMNIRPSSSTGVLFALVYNNTIPLSVAVLTKEEE DANLQVFLDGVSVATLDSLMLCYPDRLTVHLNVTPTELQISANSSTVSYMTSDALQEALELLNRTMQNPV NTYVGGIPDDIPLPLTPVSAFYHGCMDITVNDRQLDFDEALSKHNSIKSHSCPPVSQTHRDVLHFPRE >XP_020745047.1 vitamin K-dependent protein S [Odocoileus virginianus texanus] MAVLSRQHASQVLVRRRRANSLLEETKKGNLERECIEELCNKEEAREVFENNPETEYFYPKYLGCLGSFR AGLFTTARLSTNTYPDLRSCVNAIPDQCNPLPCNEDGYLSCKDGQATFTCICKSGWQGEKCESDINECKD PANVNGGCSQICENTPGSYHCSCKNGFVMLSNKKDCKDVDECVLKPSICGTAVCKNIPGDFECECAEGYK YNPVSKSCDDVDECSENLCAQLCVNYPGGYSCYCDGKKGFKLAQDQKSCEAVPVCLPLDLDKNYELLYLA EQFVGVVLYLKFRLPETTRFSAEFDFRTYDSEGVILYAESSDHSAWFLIALREGKIEIQFKNENTVKMTT GGKVINDGLWNMVSVEELEQSISVKIAKEAVMNINKPESLFKPTNGFLETKVYFAGIPRKLENALIRPIN PRLDGCIRGWNLMNQGTSGVKEIIQEKQNKHCLVTVERGSYYPGTGVAQFSIDYKNESNPEAWQINASLN IRPSAGTGVMLALVSGDTVPFALSLVDSATEKLQDILVSVESTVIARIQAISLCSDQQTFLEIRINRNNL ELSTQLTKDSFHSEDFQRQFALLDEAMKGTVATYLGGLPDVPFSATPVNAFYQGCMEVNINGVQLDLDEA ISKHNDIRAHSCPSVWQKTKQT >XP_030271164.1 vitamin K-dependent protein S [Sparus aurata] MWIKKRALGESLACLVFLVTLADAYRFLSQTTAAQFLSRHKRANSLFEEHKKGNLERECIEELCNKEEAR EIFENQPETEYFYPKYVVCLGSHRVGINNQNSNSGIPSDLRTCVTEISNQCTPYPCYKEGSENCVDGQAS FTCVCKPGWKGPRCEDDINECIDPEYPAGCDQKCHNLPGSFQCLCEDGYFISNKINCVDINECILFPSSC EEPAKCVNTPGMYECQCPQGFKYNFTSRTCNDVDECEFNVCDGTCINTEGSYSCHCDGRQGLRLAEDKRY CEQIPVCVDLYDHKHPEMLYLGEQFAGLPVIYLRFRLPENTKFAAEFDFRTFDPEGVVLYAESSQDSWFM LGLRGGRIEVQFKNQHTFKVTSGGKAINDGQWHVISVDELESSISVKISKEAVMSINSPESLFTSVNGKL ETKVYIAGLPNRTDNVIKPINPRLDGCIRGWNLMNQGASGVKEVIQEKKSKHCFVYVERGSFFTGVGLAQ FNINYSDSGRWNVDVHMNIRPSSSTGVIFALVYNNTVPLSIAVVTQGEGEANLQVFLDGISVATLDSIML CYPDRLTVHLNVTPTEIQISANSSTVTYMKSDDLLKALERLNTTMQNPISTYVGGIPEDVPLPATPVMAF YHGCMEISINDQQLDFDEALSKHNSIKSHSCPPVSAPDSRPDAPHPHRE >XP_040194662.1 vitamin K-dependent protein S [Rana temporaria] MMLLSSFCLILLASTLLMTTLSEGRTFLSSQSASQFLTRKRRANSFFEESKGGDLERECIEELCNKEEAR EIFENAPETEFFYPRYLACLGSHRNGNANKLSYLDYDGPADLRSCVTALPDQCKPMPCHKEGYKECKDGK GNYTCVCKPGWQGVRCNEDINECEDPEKENAGCSQRCVNFPGGYRCACEDGYYLLADKHTCNDRNECELS PVICGGAKCRNTPGKYECDCNSGYRFNTSSKTCEDVDECAEDVCSQMCVNMPGSYKCYCEGRKRFKLAGD KKSCERIPTCVPLNLETNYELLYLAEQFTGIPVVYLRFKLPDVTRFSAEFDFRTYDGEGVILYAESADAT SWFLLALRDGKIEIQFKNDLWTKVTTGGKSINNGDWHIVSVEELENSISVKIAKEAVMNINNPKYLFKPV NGILETKVYIAGLPRKIENLIKPINPRLDGCIRGWNLMNQGALGVKEFIQGKQSKHCLVDVEEGSYYPGG GLAHFKLNYTDITSIEEDWIVNVTLDIRSSTGTGVMFALVKEDTVPLAIAIEDQSSDIVQDIIVSIKGIT VARLSTKRICTDKNLFVGITATKSALDITSDSYTEIRYANKEEMKTQLSVLDQEMKGQLDTYLGGIPDIP PTATPVSAFYIGCMDVAINGNLIDLDEAVSKQNDIRSHSCPLIS >XP_039251316.1 vitamin K-dependent protein S-like [Styela clava] MLNVMKLKIVLLLHILLGVNEGISDSPFIDRKEASRFLGRTKRSNSFWEEIKSGNQERECIEEDCSMEEAYEVFDNNFKA NQFWKKYLRCNQALPRRYKQQGKIRIARQASRRSERENVKLRACISDEDQCNPFPCVRSNTAECVDTVSSFKCVCKNGFA GRKCESPLNECLSNPCQNSAICEDEIGGFTCFCDSNHEGIFCEIEVNDCRNTVEKQCSAVGGICQQRDAGDAYTCVCNPG YQGELCKHDVDECLNSTSCEQECHNTVGSFTCTCGHGFLIDTTTRTTCKDIDECNDVSHGCISQDFCHNTPGSFYCTCKH GFQLDETYRRYCDDIDECADENGGCPIIEGGCGLNGKTCKTCNNFDGGFNCYCPSGFNSYVEGGDCTDINECESSYHGCQ QKCENFPGGYRCLCSEGYMLNFNGKTCSDINECLKDHGCSYRCSNNVGSYYCTCKRGFELDDDQRTCIDTDECQGVTKCD QTCINTDGGYKCGCNPGYRLLGKYKCSEIDECRPRPCGNNGNCIDEVNGYRCECFEGFTGKLCDVGTDPCAGDPCLNSGV CSAFDSGYVCRCAHGYIGPRCQTKHIEMCEIGYRREDGQCIDIDECAETTGLCQQICHNTKGSYTCTCDAGFNMNGLNCE DIDECLNSPCQQVCTNSIGSYDCSCSEGYSLNESDDTCEELFACVGNSPQMLPEKHFLLGTRKIDYISQTFVESSSSFQI GFDFRTFDTDGMLVAVVCSDVEQHYIFLLHADGQLTLAAFVSWPPKIEITKPKNALVLSDGQWHSIILRKRKNRVTVMEG KNKLLDLKFMKNKFGSAGQIYYGGIPGDVTVPTTIRDTDLYFQGCLKGNYTHGFTIAGDSKMPGIHNGCFESIEKGMYFD GSGFLHQSVELQTNLRMRFEFKSLSAQGVIIFAEDALRSRFSVTIAGNQIIASLTTSRNETRSSTFTTSNGELLCDQIWH ICDFTITSNMVRLHVDGVAAGQDNISDSKRVQFTGLVDLYIGGRPGATSRSSYTGSLRNIKINRKDLSLDNIVEMNGVRL HSIPAL
Mafft alignment of selected proteins >sp|P07225|PROS_HUMAN Vitamin K-dependent protein S OS=Homo sapiens OX=9606 GN=PROS1 PE=1 SV=1 ---------MRVLGGRC-GALLACLLLVL--PVS----EAN------------------- -------------FLSKQQASQVLVRKRRANSLLEETKQGNLERECIEELCNKEEAREVF ENDPETDYFYPKYLVC----------LRSFQTGLFT-AARQSTNAYPDLRSCVN------ -----AIPDQCSPLPCNE-DGYMSCK-DGKASFTCTC----------------------- -----------------------------------------------------------K PGWQGEK-------CEF--DINECKD---------------------------------- ------------------------------------------------------------ ------------------------PSNING------------------GCSQICDNTPGS YHCSCKNGFVMLSNKKDCKDVDECS----------------------------------- ------------------------------------------LKPSICGT---------- ------------------------------------------------------------ -------------------------AVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE NMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCL---PLNLDTKYELL------ YLAEQFAGV-VLYLKFRLPEIS--------RFSAEFDFRTYDSEGVILYAESIDHSAWLL IALR-GGKIE----VQLKNEHTSKITTGGDVINNGLWNM---VSVEELEHSISIKIAKEA VMDINKPGPLFKPENGLLETKVYFAGFPRKVE-SELIKPINPRLDGCIRSWNLMKQGASG IKEIIQEKQNKHCLVTVEKGSYYPGSGIAQFHIDY--NNVSS-AEGWH-VNVTLNIRPST GTGVML----ALVSGNNTVPFA----VSLVDSTSEKSQDILLSVENTVIYRIQALSLCSD QQSHLEFRVNRNNLELSTPLKI----ETISHE--DLQRQLAVLDKAMKAKVA--TYLGGL P-DVPFSATPVNAFYNGCME------VNINGVQLDLDEAISKHNDIRAHSCPSVWKKTKN S-------- >tr|F1QK29|F1QK29_DANRE Vitamin K-dependent protein S OS=Danio rerio OX=7955 GN=pros1 PE=4 SV=1 ---------MRSLKAACSGSELGLLLLLLSATLC---GSQR------------------- -------------FLPQSKASEFLLRHRRANTLFEESKKGNLERECIEELCNKEEAREIF ENNLETEYFYPRYVVC----------LGSHRVGINN----PEPGIPQNLRTCVE------ -----EISNQCLPPPCYK-EGSERCV-DGQGSYRCVC----------------------- -----------------------------------------------------------K PGWRGQR-------CEQ--DIDECED---------------------------------- ------------------------------------------------------------ ------------------------P-EFPA------------------GCSQTCFNLPGS FTCGCESGYY-TNDGVHCIDIDECV----------------------------------- ------------------------------------------LFPSVCVE---------- -------------------P---------------------------------------- -------------------------SKCINAPGTFECRCQLGYTYNMSSHTCVDVDECLE DACAGECVNAVGSFSCQCDGRRGLQLDEDGLGCVSIPQCL---QLYDHKHKEML------ YLGEQFSGLPVIYLRFRLQPHT--------RFAAEFDFRTFDPEGVILYAESSPDS-WIM LGLR-SGRIE----VQFKNEHSIKMTSGGKAINDGQWHV---ISVEELSGSISVKISKEA VMSINSPERLFTPVNDKLETKVYIAGLPNHNQ-S-LIKTINPRLDGCIRGWNLMNQGASG VKEVIQEKESKHCYVHVEKGSFFSGGGHALFNIDY--S---V-SGQWK-LDVVMSLRPSS TTGVIL----ALVSN-NTVPLL----VAVVSLGPDDA-ELQVLLDGVCVATLQSLMLCYP DRLVVELRASAEGLQISANSSS-----VSYSEPQTLSAALHKLDTAMHTQPQ--TYIGGL P-DLPLSITPVSAFYHGCLE------LVIGGRQLDFDEAVSKDNSIKSHSCPPYSITQS- PSAP----- >NP_035303.1 vitamin K-dependent protein S preproprotein [Mus musculus] ---------MRVLSARF-RVLLACLALVI--PVS----ETN------------------- -------------FLSKERASQVLVRKRRANTLFEETMKGNLERECIEELCNKEEAREVF ENNPETDYFYPKYLGC----------LGAFRVGSFH-AARQSANAYPDLRSCVK------ -----AISDQCDPIPCNE-DGYLACQ-DGQAAFTCFC----------------------- -----------------------------------------------------------K PGWQGDR-------CQY--DVNECKD---------------------------------- ------------------------------------------------------------ ------------------------PSNVNG------------------GCSQICDNTPGS YHCSCKRGFAMLPNKKDCKDLDECA----------------------------------- ------------------------------------------LKPSVCGT---------- ------------------------------------------------------------ -------------------------AVCKNIPGDFECECPDGYRYDPSSKSCKDVDECSE NMCAQLCVNFPGGYSCYCDGKKGFKLAQDQKSCEGIPVCL---SLDLDKNYELL------ YLAEQFAGV-VLYLKFRLPDIT--------RFSAEFDFRTYDSEGIILYAESLDHSNWLL IALR-DGKIE----VQFKNEFSTQITTGGNVINNGIWNM---VSVEELDDSVSIKIAKEA VMNINKLGSLFKPTDGFLDTKIYFAGLPRKVE-SALIKPINPRLDGCIRGWNLMKQGALG AKEIIEGKQNKHCFLNVEKGSYYPGSGIAQFSIDY--NNVTN-AEGWQ-MNVTLNIRPST GTGVML----ALVSG-GTVPFA----LSLVDSRSGTSQDIVVFVENSVVARLEAVSLCSD QQSQLKCNVNRNGLELWTPLRK----DVIYSK--DLQRQLAVLDKAMKRTVA--TYLGGI P-DISFSATPVNAFYSGCME------VNINGVQLDLDEAISKHKDIRAHSCPSVRKIQKN F-------- >NP_112348.2 vitamin K-dependent protein S precursor [Rattus norvegicus] ---------MRVLSVRF-RVLLACLALVL--PVS----ETN------------------- -------------FLSKERASQVLVRKRRANTLLEETKKGNLERECIEELCNKEEAREVF ENNPETDYFYPKYLGC----------LGAFRVGAFS-AARQSANAYPDLRSCVN------ -----AIPDQCDPMPCNE-DGYLSCK-DGQGAFTCIC----------------------- -----------------------------------------------------------K PGWQGDK-------CQF--DINECKD---------------------------------- ------------------------------------------------------------ ------------------------PSNING------------------GCSQTCDNTPGS YHCSCKIGFAMLTNKKDCKDVDECS----------------------------------- ------------------------------------------LKPSVCGT---------- ------------------------------------------------------------ -------------------------AVCKNIPGDFECECPNGYRYDPSSKSCKDVDECSE NTCAQLCVNYPGGYSCYCDGKKGFKLAQDQRSCEGIPVCL---SLDLDKNYELL------ YLAEQFAGV-VLYLKFRLPDIT--------RFSAEFDFRTYDSEGIILYAESLDHSNWLL IALR-EGKIE----VQFKNEFSTQITTGGNVINNGIWNM---VSVEELDDSVSIKIAKEA VMNINKLGSLFKPTDGFLDTKIYFAGLPRKVE-SALIKPINPRLDGCIRGWNLMKQGALG AKEIVEGKQNKHCFLTVEKGSYYPGSGIAQFSIDY--NNVTN-AEGWQ-INVTLNIRPST GTGVML----ALVSG-DTVPFA----LSLVDSGSGTSQDILVFVENSVAAHLEAITLCSE QPSQLKCNINRNGLELWTPVRK----DVIYSK--DLQRQLAILDKTMKGTVA--TYLGGV P-DISFSATPVNAFYSGCME------VNINGVQLDLDEAISKHNDIRAHSCPSVRKIQKN F-------- >NP_776863.1 vitamin K-dependent protein S precursor [Bos taurus] ---------MRVLGGRT-GTLLACLALVL--PVL----EAN------------------- -------------FLSRQHASQVLIRRRRANTLLEETKKGNLERECIEELCNKEEAREIF ENNPETEYFYPKYLGC----------LGSFRAGLFT-AARLSTNAYPDLRSCVN------ -----AISDQCNPLPCNE-DGFMTCK-DGQATFTCIC----------------------- -----------------------------------------------------------K SGWQGEK-------CES--DINECKD---------------------------------- ------------------------------------------------------------ ------------------------PVNING------------------GCSQICENTPGS YHCSCKNGFVMLSNKKDCKDVDECV----------------------------------- ------------------------------------------LKPSICGT---------- ------------------------------------------------------------ -------------------------AVCKNIPGDFECECAEGYKYNPVSKSCDDVDECAE NLCAQLCVNYPGGYSCYCDGKKGFKLAQDQKSCEAVPVCL---PLDLDKNYELL------ YLAEQFVGV-VLYLKFRLPETT--------RFSAEFDFRTYDSEGVILYAESSDHSAWFL IALR-EGKIE----IQFKNEKTTKMTTGGKVINDGLWHM---VSVEELEQSISVKIAKEA VMNINKPGSLFKPTNGFLETKVYFAGVPRKME-NALIRPINPRLDGCIRGWNLMNQGTSG VKEIIQEKQNKHCLVNVEKGSYYPGTGVAQFSINY--KNESN-PEAWQ-INVSLNIRPSA GTGVML----ALVSD-NTVPFA----LSLVDSATEKLQDILVSVESMVIGRIEAISLCSD QQTFLEIRVNRNNLELSTQLRK----DSFHSE--DFQRQFAILDEAMKGTVV--TYLGGL P-DVPFSATPVNAFYQGCME------VNINGVQVDLDEAISKHNDIRAHSCPSVWQKTKH T-------- >XP_020926395.1 vitamin K-dependent protein S [Sus scrofa] ---------MRVLGGRC-GALLACLALAL--PVL----EAN------------------- -------------FLSKQHASQVLIRKRRANSMLEERKQGNLERECIEELCSKEEAREVF ENDPETEYFYPAYLAC----------LGSFRAGLFT-AARLSTNAYPDLRSCVN------ -----AIPDQCNPLPCNE-DGYLTCK-DGQAMFTCIC----------------------- -----------------------------------------------------------K SGWEGEK-------CEL--DINECKD---------------------------------- ------------------------------------------------------------ ------------------------PANING------------------GCSQICDNTPGS YHCSCKSGFIMLSNKKDCKDVDECS----------------------------------- ------------------------------------------VKPSICGT---------- ------------------------------------------------------------ -------------------------AVCKNIPGDFECECPEGYRYNPTLKYCEDVDECSE NMCAQLCVNYPGGYSCYCDGKRGFKLAQDQKSCEAVPVCL---PLNLDKNYELL------ YLAEQFVGV-VLYLKFRLPEIT--------RFSAEFDFRTYDSEGVILYAESSDHSAWFL IALR-DGKIE----IQFKNEHTTKITTGGRVINDGLWNM---VSVEELEQSISVKIAKEA VMNINKPESLFKPTNGFLETKVYFAGLPRKVE-NALIKPINPRLDGCIRGWNLMNQGASG VKEIIQEKQNKHCLVTVEKGSYYPGSGVAQFSIDY--KNVSS-AGAWQ-VNVSLNIRPSA GTGVML----ALVSG-NTVPFA----LSLVDSATEKLQDIVVSVENVEIARIKALSLCSS LQSLLEMRVSVNSLELLTQFEK----RRISSE--DYQGQFAILDKAMEGTVA--TYLGGL P-DVPFSATPVNAFYNGCMD------VIINGVPLDLDEAIAKHNDIRAHSCPSVWKNTRN T-------- >XP_043304830.1 vitamin K-dependent protein S [Cervus canadensis] ---------MRVPGGRT-GTLLACLALVL--PVL----EAN------------------- -------------FLSRQHASQVLVRRRRANTLLEETKKGNLERECIEELCNKEEAREVF ENNPETEYFYPKYLGC----------LGSFRAGLFT-TARLSTNTYPDLRSCVN------ -----AIPDQCNPLPCNE-DGYLSCK-DGQATFTCIC----------------------- -----------------------------------------------------------K SGWQGEK-------CES--DINECKD---------------------------------- ------------------------------------------------------------ ------------------------PANVNA------------------GCSQICVNTPGS YHCSCKNGFVMLSNKKDCKDVDECV----------------------------------- ------------------------------------------LKPSICGT---------- ------------------------------------------------------------ -------------------------AVCKNIPGDFECECAEGYKYNPVSKSCDDVDECSE NLCAQLCVNYPGGYSCYCDGKKGFKLAQDQKSCEAVPVCL---PLDLDKNYELL------ YLAEQFVGV-VLYLKFRLPETT--------RFSAEFDFRTYDSEGVILYAESSDHSAWFL IALR-EGKIE----IQFKNENTVKMTTGGKVINDGLWNM---VSVEELEQSISVKIAKEA VMNINKPESLFKPTNGFLETKVYFAGIPRKLE-NALIRPINPRLDGCIRGWNLMNQGTSG VKEIIQEKQNKHCLVTVERGSYYPGTGVAQFSIDY--KNESN-PEAWQ-INVSLNIRPSA GTGVML----ALVSG-DTVPFA----LCLVDSATEKLQDILVSVESMVIARIQAISLCSD QQTFLEIRVNRNNLELLTQLTK----DSFHSE--DFQRQFAILDEAMKGTVA--TYLGGL P-DVPFSATPVNAFYQGCME------VNINGVQLDLDEAISKHNDIRAHSCPSVWQKTKH T-------- >KAB0344409.1 hypothetical protein FD754_021335 [Muntiacus muntjak] MFAYCFVYILFTVFILF-LTLHTWLLYFQ--PTLQETQEMA------------------- -------------VLSRQHASQVLVRRRRANSLLEETKKGNLERECIEELCNKEEAREVF ENNPETEYFYPKYLGC----------LGSFRAGLFT-TARLSTNTYPDLRSCVN------ -----AIPDQCNPLPCNE-DGYLSCK-DGQATFTCIC----------------------- -----------------------------------------------------------K SGWQGEK-------CES--DINECKD---------------------------------- ------------------------------------------------------------ ------------------------PANVNG------------------GCSQICVNTPGS YHCSCKNGFVMLSNKKDCKDVDECV----------------------------------- ------------------------------------------LKPSICGT---------- ------------------------------------------------------------ -------------------------AVCKNIPGDFECECAEGYKYNPVSKSCDDVDECSE NLCAQLCVNYPGGYSCYCDGKKGFKLAQDQKSCEAVPVCL---PLDLDKNYELL------ YLAEQFVGV-VLYLKFRLPETT--------RFSAEFDFRTYDSEGVILYAESSDHSAWFL IALR-EGKIE----IQFKNENTVKMTTGGKVINDGLWNM---VSVEELEQSISVKIAKEA VMNINKPESLFKPTNGFLETKVYFAGIPRKLE-NALIRPINPRLDGCIRGWNLMNQGTSG VKEIIQEKQNKHCLVTVERGSYYPGTGVAQFSIDY--KNESN-PEAWQ-INVSLNIRPSA GTGVML----ALVSG-DTVPFA----LSLVDSATEKLQDILVSVESMVIARIQAISLCSD QQTFLEIRVNRNNLELLTQLTK----DSFHSE--DFQRQFAILDEAMKGTVA--TYLGGL P-DVPFSATPVNAFYQGCME------VNINGVQLDLDEAISKHNDIRAHSCPSVWQKTKH T-------- >KAF4025963.1 hypothetical protein G4228_018124 [Cervus hanglu yarkandensis] ---------MRVPGGRT-GTLLACLALVL--PVL----EAN------------------- -------------FLSRQHASQVLVRRRRANTLLEETKKGNLERECIEELCNKEEAREVF ENNPETEYFYPKYL---------------------------------------------- -----AIPDQCNPLPCNE-DGYLSCK-DGQATFTCIC----------------------- -----------------------------------------------------------K SGWQGEK-------CES--DINECKD---------------------------------- ------------------------------------------------------------ ------------------------PANVNA------------------GCSQICVNTPGS YHCSCKNGFVMLSNKKDCKDVDECV----------------------------------- ------------------------------------------LKPSICGT---------- ------------------------------------------------------------ -------------------------AVCKNIPGDFECECAEGYKYNPVSKSCDDVDECSE NLCAQLCVNYPGGYSCYCDGKKGFKLAQDQKSCEAVPVCL---PLDLDKNYELL------ YLAEQFVGV-VLYLKFRLPETT--------RFSAEFDFRTYDSEGVILYAESSDHSAWFL IALR-EGKIE----IQFKNENTVKMTTGGKVINDGLWNM---VSVEELEQSISVKIAKEA VMNINKPESLFKPTNGFLETKVYFAGIPRKLE-NALIRPINPRLDGCIRGWNLMNQGTSG VKEIIQEKQNKHCLVTVERGSYYPGTGVAQFSIDY--KNESN-PEAWQ-INVSLNIRPSA GTGVML----ALVSG-DTVPFA----LSLVDSATEKLQDILVSVESMVIARIQAISLCSD QQTFLEIRVNRNNLELLTQLTK----DSFHSE--DFQRQFAILDEAMKGTVA--TYLGGL P-DVPFSATPVNAFYQGCME------VNINGVQLDLDEAISKHNDIRAHSCPSVWQKTKH T-------- >XP_018104341.1 vitamin K-dependent protein S isoform X2 [Xenopus laevis] ---------MGLLDKVC-LVLLASTLLAV--TLA---EGLT------------------- -------------FLSPQHASQFLSRRRRANSFLEESKGGNLERECIEELCNKEEAREIF ENVPETEYFFPKYLAC----------LGAHRSGTLSKLSYLNFDGPVDLRACVN------ -----AIPDQCTPLPCNK-ERSKECI-DGKGNFTCIC----------------------- -----------------------------------------------------------K PGFQGPL-------CDE--DINECVD---------------------------------- ------------------------------------------------------------ ------------------------PVNPNA------------------GCNQKCLNLPGS YRCACEDGYYMLPNKHTCSDRNECE----------------------------------- ------------------------------------------MFPTICGS---------- ------------------------------------------------------------ -------------------------AVCKNTPGKYECECDNGYRYNSSAKACEDIDECAV RSCSQICVNNPGGYTCYCDGRRKYKLAQDKTSCESIPVCV---PLNLETNYELL------ FLAEQFTGIPVVYLRFKLPDVS--------RFSAEFDFRTYDGEGVILYAESADSTSWFL LALR-DGKIE----IQFKNELWTKVTTGGKAINNGEWHI---ITVEELENIISVKIAKEA VMNINNPRSLFKSSNGILEIKVYIAGLPRKVD-N-IIKPINPRLDGCIRGWNLMNQGALG VKEVIQGKQSKHCLVTVERGSYYPGGGVARFIMNY--N-VST-NDEWV-ANITFNIRSST GIGVMF----SLVNG-ETVPLA----IAIEDLGSDFLQGIVVSIHSATVARLTTKRICTD KNLLISVSITKNTLVLNANSYT----DITYASQVELDKQLSILDQAMQENPD--TYLGGI P-DIPVAATPVSAHYVGCMD------VTINNELMDLDGAVSKQNDIRSHSCPLIL----- --------- >OWK00463.1 PROS1 [Cervus elaphus hippelaphus] ---------M----------------------------VGQ------------------- -------------VLSRQHASQVLVRRRRANTLLEETKKGNLERECIEELCNKEEAREVF ENNPETEYFYPKYLGC----------LGSFRAGLFT-TARLSTNTYPDLRSCVN------ -----AIPDQCNPLPCNE-DGYLSCK-DGQATFTCIC----------------------- -----------------------------------------------------------K SGWQGEK-------CES--DINECKD---------------------------------- ------------------------------------------------------------ ------------------------PANVNA------------------GCSQICVNTPGS YHCSCKNGFVMLSNKKDCKDVDECV----------------------------------- ------------------------------------------LKPSICGT---------- ------------------------------------------------------------ -------------------------AVCKNIPGDFECECAEGYKYNPVSKSCDDVDECSE NLCAQLCVNYPGGYSCYCDGKKGFKLAQDQKSCEAVPVCL---PLDLDKNYELL------ YLAEQFVGV-VLYLKFRLPETTRLSLCPLFRFSAEFDFRTYDSEGVILYAESSDHSAWFL IALR-EGKIE----IQFKNENTVKMTTGGKVINDGLWNMDILVSVE----SMSVLWQRKQ IHGCHS-------------------GLASTVG-----KSLNT---------DAQSEAEAQ VRKLEEQRLEKDVWVST-----------ALLTLRW--Q-----TRNWLWVCLHFDWRQTK MKS-------EVVLN-HIIILM-----------------------GINFKFVQKMNLN-- -------KVKFTSLQKKACSDS-------------WKPEFTHVPTLLSHNSE--DFCSVF P-D---SCYLCSTFQEACLPNDSSFWVKQKGRWEQCSDAVSSQGLC---SFPPYL----- --------- >XP_416641.3 vitamin K-dependent protein S [Gallus gallus] ---------MRPRGGRC-VPLLAGLAVAL--ALA---EAAT------------------- -------------FLSHQYASEFLARKRRANSFMEESKKGNLERECVEELCNKEEAREIF ENNPETEYFYPKYLSC----------LASYRAGVFR-VPTVTPDSPANLRVCVS------ -----EISNQCSPLPCHR-DGYKECI-DGQAKYTCIC----------------------- -----------------------------------------------------------K PGWQGEN-------CEE--DINECED---------------------------------- ------------------------------------------------------------ ---------------------------ING------------------GCSQRCSNLPGS YRCLCEDGYFMHSNKRDCRDINECA----------------------------------- ------------------------------------------LHPNICGT---------- ------------------------------------------------------------ -------------------------AVCKNTLGKYECECAEGYKYNSTSKSCEDIDECAE NTCAQLCVNSPGSYSCYCDGKKGFKLSKDMKNCESVPVCI---PLNLERNYELL------ YLAEHFTGIYVLYLKFKLPNVT--------RFSAEFDFRTYDSEGIILYAESFDNTAWIL LALR-DGKIE----IQFKNEFGTKVTSGGKAINDGLWHI---ISVEELENSISVKIAKEA VMNINSPGTLFKQSHGFLETKVYIAGLPDKVG-DTLIKQINPRLDGCIRAWNLMNQGHSG VKEVIQEKQSKHCLVTVERGSFYPGTGMAQFDINY--NNRDS-AEDWL-INVTMTIRPST DTGVMF----ALVSN-ETVPLA----LSIVDSNSSDSQEIIVTIGNITVARLESKKLCTP RKVQVGLLVTKQQLQLSVDSRT----DQSNSE------QLSVLHQAMMTNVV--TYLGGL P-DVPLGATLVTAFYNGCME------VKVNSRQLDLDEAISKHNSIRSHSCPLIME---- --------- >XP_516603.3 vitamin K-dependent protein S [Pan troglodytes] ---------MRVLGGRC-GALLACLLLVL--PVS----EAN------------------- -------------FLSKQQASQILVRKRRANSLLEETKQGNLERECIEELCNKEEAREVF ENDPETDYFYPKYLVC----------LRSFQTGLFT-AARQSTNAYPDLRSCVN------ -----AIPDQCSPLPCNE-DGYMSCK-DGKASFTCTC----------------------- -----------------------------------------------------------K PGWQGEK-------CEF--DINECKD---------------------------------- ------------------------------------------------------------ ------------------------PSNING------------------GCSQICDNTPGS YHCSCKSGFVMLSNKKDCKDVDECS----------------------------------- ------------------------------------------LKPSICGT---------- ------------------------------------------------------------ -------------------------AVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE NMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCL---PLNLNTKYELL------ YLAEQFAGV-VLYLKFRLPEIS--------RFSAEFDFRTYDSEGVILYAESIDHSAWLL IALR-GGKIE----VQLKNEHTSKITTGGDVINNGLWNM---VSVEELEHSISIKIAKEA VMDINKPGPLFKPENGLLETKVYFAGFPRKVE-SELIKPINPRLDGCIRSWNLMKQGASG IKEIIQEKQNKHCLVTVEKGSYYPGSGIAQFHIDY--NNVSG-AEGWH-VNVTLNIRPST GTGVML----ALVSGNNTVPFA----VSLVDSTSEKSQDILLSVENTVIYRIQALSLCSD QQSHLEFRVNRNNLELSTPLKI----ETISHE--DLQRQLAVLDKAMKAKVA--TYLGGL P-DVPFSATPVNAFYNGCME------VNINGVQLDLDEAISKHNDIRAHSCPSVWKKTKN S-------- >XP_038300575.1 vitamin K-dependent protein S isoform X1 [Canis lupus familiaris] ---------MRLLAGRC-GALLACLVLVL--PVS----EAN------------------- -------------FLSKEHASQVLVRKRRANSMFEETKKGNLERECIEELCNKEEAREIF ENDPETDYFYPKYLGC----------LGSFRAGLFT-AARLSTDAYPDLRSCVT------ -----AIPDQCSPLPCNE-DGYKTCR-DGQATFTCIC----------------------- -----------------------------------------------------------K PGWQGDR-------CEY--DINECKD---------------------------------- ------------------------------------------------------------ ------------------------PSNING------------------GCSQMCDNTPGS YHCSCKSGFVMLLNKKDCKDVDECS----------------------------------- ------------------------------------------IMPDICGA---------- ------------------------------------------------------------ -------------------------AVCKNIPGDYECECAEGYRYNPALKSCEDVDECSE NLCAQLCVNYPGGYSCYCDGRKGFKLAQDHKSCEAVPVCL---PLNLDKNYELL------ YLAEQFVGV-VLYLKFRLPEIT--------RFSAEFDFRTYDSEGVILYAESLDRSAWFL IALR-DGKIE----IQFKNEFTTKITTGGKAINNGLWNT---VSVEELEYSISIKIAKEA VMNINKPGRLFKPSNGFLETKVYFAGLPRKVE-NVLIRPINPRLDGCIRGWNLMNQGASG VKEIIQEKQNKHCLVTVEKGSYYPGSGVAVFGIDYTPDSDSA-AGAWQ-LNASLSVRASA GTGVLL----ALVSG-SSVPLA----LSLADSISETLQDILVSVENIVISRIEAVNLCSN QQVHLELKVNRNNLELSTPVKK----DTISSE--DLPQQFASLDKAMKGTVT--TYLGGL P-DIPFGATPVNVFYNGCME------VNINGVQLDLDEAISKHNDIRAHSCPSVLKSTKN S-------- >XP_002716802.1 PREDICTED: vitamin K-dependent protein S [Oryctolagus cuniculus] ---------MRVLGGRC-GALLACLALVL--PVS----EAN------------------- -------------FLTKQHASQVLVRKRRANSMLEETKKGNLERECIEELCNKEEAREVF ENDPETDYFYPKYLGC----------LGSFRAKLFT-ATRRSANPYPDLRSCVN------ -----AIPDQCNPLPCSE-EGYLNCK-DGQATFTCIC----------------------- -----------------------------------------------------------K PGWQGEK-------CEI--DINECKD---------------------------------- ------------------------------------------------------------ ------------------------PTNING------------------GCSQICDNTAGS YHCSCKSGFVMLANEKDCKDMDECS----------------------------------- ------------------------------------------VKPSVCGT---------- ------------------------------------------------------------ -------------------------AVCKNTPGDFECECSEGYRYNPTAKSCEDIDECSE NMCAQLCVNYPGGYSCYCDGKKGFKLAQDKKSCEAVPVCL---PLDLDKNYQLL------ YLAEQFVGA-VLYLKFHLPEIT--------RFSAEFDFRTYDSEGVILYAESLDHSTWFL IALR-QGKIE----IQFKNDYAAQITTGGQVINDGLWNM---VSVEELEHSVSIKIAQEP VMNINKPGSLFKPTNGFLETKVYFAGLPRKVE-NALIRPINPRLDGCMRGWNLMKQGASG VKEIIQQKQKKHCLVTVEKGSYYPGSGIAQFHIDY--NNLSY-VEDWQ-VNVTLKIRPST GTGVML----ALVSG-NTVPFA----LSLVQSTSETSQDILVSVENRVIYQLESISLCSG QQSQLEFSVSRNHLELSTPLVK----DVIYSE--DLQRHLAVLDEAMKGTVT--TYLGGL P-DVPFNATPVNAFYNGCME------VNINGVQLDLDEAVSKHNDIRAHSCPSVWNDKTN S-------- >XP_024100978.1 vitamin K-dependent protein S isoform X1 [Pongo abelii] ---------MRVPGGRC-WALLACLLLVL--PVS----EANFCLYFRNDFIYNRTCISVL VGLSGCNFFYSICFLSKQQASQVLVRKRRANSLLEETKQGNLERECIEELCNKEEAREVF ENDPETDYFYPKYLVC----------LRSFQTGLFT-AARQSTNAYPDLRSCVN------ -----AIPDQCSPLPCNE-DGYMSCK-DGKASFTCTC----------------------- -----------------------------------------------------------K PGWQGEK-------CEF--DINECKD---------------------------------- ------------------------------------------------------------ ------------------------PSNING------------------GCSQICDNTPGS YHCSCKSGFVMLSNKKDCKDVDECS----------------------------------- ------------------------------------------LKISVCGT---------- ------------------------------------------------------------ -------------------------AVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE SMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCL---PLNLDTKYELL------ YLAEQFAGV-VLYLKFRLPEIS--------RFSAEFDFRTYDSEGVILYAESIDHSAWLL IALR-GGKIE----VQLKNEHTSKITTGGDVINNGLWNM---VSVEELEHSISIKIAKEA VMDINKPGPLFKPENGLLETKVYFAGFPRKVE-SELIKPINPRLDGCIRSWNLMKQGASG IKEIIQEKQNKHCLVTVEKGSYYPGSGIAQFHIDY--NNVSS-AEGWH-INVTLNIRPSM GTGVML----ALVSGNSTVPFA----VSLVDSTSEKSQDILLSVENTVIYRIQALSLCSD QQSHLEFRVNRNNLELSTPLKI----ETISHE--DLQRQLAVLDKAMKAKVA--TYLGGL P-DVPFSATPVNAFYNGCME------VNINGVQLDLDEAISKHNDIRAHSCPSVWKKTKN S-------- >XP_019475114.1 vitamin K-dependent protein S [Meleagris gallopavo] ------------------------------------------------------------ ---------------------------------MEESKKGNLERECIEELCNKEEAREIF ENNPETEYFYPKYLSC----------LASYRAGVFR-VTAVTPDSPADLRACVN------ -----EISNQCSPLPCHR-DGYKDCI-DGQARYTCIC----------------------- -----------------------------------------------------------K PGWQGEN-------CEK--DINECED---------------------------------- ------------------------------------------------------------ ---------------------------FNG------------------GCSQRCSNLPGS YRCLCEDGYFMHSNKRDCRDINECA----------------------------------- ------------------------------------------LHPNICGT---------- ------------------------------------------------------------ -------------------------AVCKNTLGKYECECAEGYTYNSTSKNCEDIDECAE NTCAQLCVNSPGSYSCYCDGKKGFKLSKDMKNCESISACI---PLNLERNYELL------ YLAEQFTGIPVLYLKFKLPNVT--------RFSAEFDFRTYDSEGVILYAESLDNTAWIL LALR-DGKIE----IQFKNEFGTKVTSGGKAINDGLWHI---ISVEELENSISVKIAKEA VMNINSPGTLFKQSHGFLETKVYIAGLPRKVG-DSLIKQINPRLDGCIRAWNLMNQGHSG VKEVIQEKQSKHCLVTVERGSFYPGTGMAKFHINY--NNLDS-AEDWL-INVTMTIRPST DTGVMF----ALVSN-ETVPLA----LSIVDSNSSDSQEIIVTIGNITVASLESKKLCTP RKVQVGLLVTKQQLQLSVDSRT----DQSNSE------QLSVLHQAMMTNVV--TYLGGL P-DVPLGATLVTAFYNGCME------VKVNSRQLDLDEAILKHNSIRSHSCPLIME---- --------- >XP_034812860.1 vitamin K-dependent protein S isoform X1 [Pan paniscus] ---------MRVLGGRC-GALLACLLLVL--PVS----EANFCLYFRNDFIYNRACISVL VSLSGCNFFYSICFLSKQQASQILVRKRRANSLLEETKQGNLERECIEELCNKEEAREVF ENDPETDYFYPKYLVC----------LRSFQTGLFT-AARQSTNAYPDLRSCVN------ -----AIPDQCSPLPCNE-DGYMSCK-DGKASFTCTC----------------------- -----------------------------------------------------------K PGWQGEK-------CEF--DINECKD---------------------------------- ------------------------------------------------------------ ------------------------PSNING------------------GCSQICDNTPGS YHCSCKSGFVMLSNKKDCKDVDECS----------------------------------- ------------------------------------------LKPSICGT---------- ------------------------------------------------------------ -------------------------AVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE NMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCL---PLNLDTKYELL------ YLAEQFAGV-VLYLKFRLPEIS--------RFSAEFDFRTYDSEGVILYAESIDHSAWLL IALR-GGKIE----VQLKNEHTSKITTGGDVINNGLWNM---VSVEELEHSISIKIAKEA VMDINKPGPLFKPENGLLETKVYFAGFPRKVE-SELIKPINPRLDGCIRSWNLMKQGASG IKEIIQEKQNKHCLVTVEKGSYYPGSGIAQFHIDY--NNVSS-AEGWH-VNVTLNIRPST GTGVML----ALVSGNNTVPFA----VSLVDSTSEKSQDILLSVENTVIYRIQALSLCSD QQSHLEFRVNRNNLELSTPLKI----ETISHE--DLQRQLAVLDKAMKAKVA--TYLGGL P-DVPFSATPVNAFYNGCME------VNINGVQLDLDEAISKHNDIRAHSCPSVWKKTKN S-------- >XP_023094643.1 vitamin K-dependent protein S isoform X1 [Felis catus] MPSMAF---QLLNESRP-SSLLIQMFPGL--SFI----CTT------------------- -------------VLSKQHASQVLIRKRRANSMFEETKKGNLERECIEELCNKEEAREIF ENNPETDYFYPKYLDC----------LGSFRAGLFT-AARQSTDAYPDLRSCVT------ -----AIPDQCSPLPCNE-DGYMSCK-DGQATFTCVC----------------------- -----------------------------------------------------------K SGWQGDK-------CEY--DINECKD---------------------------------- ------------------------------------------------------------ ------------------------PSNVNG------------------GCSQICDNTPGS YHCSCKSGFVMLSNKKDCKDVDECS----------------------------------- ------------------------------------------MKPDICGT---------- ------------------------------------------------------------ -------------------------AVCKNIPGDFECECAEGYRYNPTLKSCEDVDECSE NMCAQLCVNYPGGYSCYCDGKKGFKLAQDHRSCEAVPVCL---PLNLDKNYELL------ YLAEQFVGV-VLYLKFRLPEIT--------RFSAEFDFRTYDSEGVILYAESLDHSCWFL IALR-DGKIE----IQFKNEYATKITTGGKVINNGLWNT---VSVEELEYSISVKIAKEA VMNINKPRSLFKPANGFLETKVYFAGLPRKGE-NVLIKPINPRLDGCIRGWNLMNQGASG VKEIIQEKQNKHCLVTVEKGSYYPGSGVALFSIDY--NNISN-AEGWQ-VNVSLNIRPSA GTGVMF----ALVSG-YTVPFA----LSLVDSASEKLQDILVSVENMVVSRVEAISLCSN EQFHLEVRVNRTSLELLTPLKK----DIIYSE--DLQSQLAILDIAMKERVS--TYLGGL P-DIPFSATPVNAFYNGCME------MSINGVQLDLDEAISKHNDIRAHSCPSVLKKTKN S-------- >XP_004002896.2 vitamin K-dependent protein S [Ovis aries] ---------MRVLGGLT-GTLLTCLALVL--PVL----EAN------------------- -------------FLSRQHASQVLVRRRRANSLLEETKKGNLERECIEELCNKEEAREVF ENNPETEYFYPKYLGC----------LGSFRAGLFT-TARLSTNAYPDLRSCVN------ -----AIPDQCNPLPCNE-DGYMTCK-DGQATFTCIC----------------------- -----------------------------------------------------------K SGWQGEK-------CES--DINECKD---------------------------------- ------------------------------------------------------------ ------------------------PVNVNG------------------GCSQICENTPGS YHCSCKNGFIMLSNKKDCKDVDECV----------------------------------- ------------------------------------------LKPSICGT---------- ------------------------------------------------------------ -------------------------AVCKNIPGDFECECAEGYKYNPVSKSCDDVDECSE NLCAQLCVNYPGGYSCYCDGKKGFKLAQDQKSCEAVPVCL---PLNLEKNYELL------ YLAEQFVGV-VLYLKFRLPETT--------RFSAEFDFRTYDSEGVILYAESSDHSSWFL IALR-EGKIE----IQFKNEKTVKMTTGGKVINDGLWNM---VSVEELEQSISVKIAKEA VMNINKPESLFKPTNGFLETKVYFAGVPRKVE-NALIRPINPRLDGCIRGWNLMNQGTSG VKEIIQEKQNKHCLITVERGSYYPGTGVAQFSIDY--KNESN-PEAWQ-INVSLNIRPSA GTGVML----ALVSG-NTVPFA----LSLVDSATEKLQDILVSVESMVIARIEAETLCSD QQTFLEIRVNRNNLELLTQLRK----DSFHSE--DFQRQFAILDEAMKGTVA--TYLGGL P-DVPFSATPVNAFYQGCME------VNINGVQLDLDEAISKHNDIRAHSCPSVWQNTEH T-------- >XP_030865634.1 vitamin K-dependent protein S [Gorilla gorilla gorilla] ---------MRVQGGRC-GALLACLLLVL--PLS----EAN------------------- -------------FFSKQQASQVLVRKRRANSLLEETKQGNLERECIEELCNKEEAREVF ENDPETDYFYPKYLVC----------LRSFQTGLFT-AARQSTNAYPDLRSCVN------ -----AIPDQCSPLPCNE-DGYMSCK-DGKASFTCTC----------------------- -----------------------------------------------------------K PGWQGEK-------CEF--DINECKD---------------------------------- ------------------------------------------------------------ ------------------------PPNING------------------GCSQICDNIPGS YHCSCKSGFVMLSNKKDCKDVDECS----------------------------------- ------------------------------------------LKPSICGT---------- ------------------------------------------------------------ -------------------------AVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSE NMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCL---PLNLDTKYELL------ YLAEQFAGV-VLYLKFRLPEIS--------RFSAEFDFRTYDSEGVILYAESVDHSAWLL IALR-GGKIE----VQLKNEHTSKITTGGDVINNGLWNM---VSVEELEHSISIKIAKEA VMDINKPGPLFKPENGLLETKVYFAGFPQKVE-SELIKPINPRLDGCIRSWNLMKQGASG IKEIIQEKQNKHCLVTVEKGSYYPGSGIAQFHIDY--NNVSS-AEGWH-VNVTLNIRPST GTGVML----ALVSGNNTVPFA----VSLVDSTSEKSQDILLSVENTVIYRIQAPSLCSD QQSHLEFRVNRNNLELSTPLKI----ETISHE--DLQRQLAVLDKAMKAKVA--TYLGGL P-DVPFSATPVNAFYNGCME------VNINGVQLDLDEAISKHNDIRAHSCPSVWKKTKN S-------- >XP_011488632.1 vitamin K-dependent protein S isoform X1 [Oryzias latipes] ---------MPVPRRIL-GRALAFFVLLV--TFA---DAHR------------------- -------------FLSQNTASQFLRRHRRANSGFEETKAGNLERECIEELCNKEEAREIF ENQPETEYFYPKYVVC----------LGSHRVGISN--GNSGSDIPSNLRTCVK------ -----EISNQCTPFPCYK-EGSEGCV-DGQASFTCVC----------------------- -----------------------------------------------------------K PGWKGRL-------CEY--DIDECSD---------------------------------- ------------------------------------------------------------ ------------------------P-DFPA------------------GCKHKCNNIPGS FYCMCDEGYF-LNDKINCVDINECL----------------------------------- ------------------------------------------LYRSICEE---------- -------------------P---------------------------------------- -------------------------AKCVNTPGMYECQCPPGFKYNFTSKSCDDVNECER VLCDGTCVNTVGSYTCICDGRAGLRLAVDDRYCETIPICV---DLNDYKHPEML------ YLGELFAGRPVILLHFRLPENT--------KFAAEFDFRTFDPEGVILYAESSNHS-WFM LGLR-GGRIE----VQFKNHHAFKVTSGGKFINDGEWHV---ISVDELENSISVKISNEA VMSINSPESLFTSVNGKLETKVYIAGLPNRTN-N-VIKPINPRLDGCIRGWNFMKQGPSG VKEIIQGKQSKHCFVHVERGSFFSGEGLAHFDIDY--TG--K-SGKWN-VNVEMRIRPSK STGVLF----ALVYN-NTVPLS----VAVVEKGEGDA-NLQVFLEGVSVATLDSLMLCYP ERLGIQLNVTPSEIQLSASSST-----VSYIKSDVLEKKLEVLNITMQNPVG--TYIGGI PGNIPLIATPVSAFYYGCME------ITINDQWLDFDEAHRKHNSIKSHSCPPVSASEPH PIVSHLHR- >XP_021143422.1 vitamin K-dependent protein S isoform X1 [Columba livia] ---------M---------------------SST---AETT------------------- -------------VLSQQYASQFLVRKRRANSFMEESKKGNLERECIEELCNKEEAREIF ENNPETEYFYPKYLSC----------LASHRAGVFR-VTAVTPDSPDDLRVCVN------ -----EISNQCSPLPCHK-DGYKDCI-DGQAKYTCIC----------------------- -----------------------------------------------------------K PGWQGEK-------CEE--DINECED---------------------------------- ------------------------------------------------------------ ---------------------------LNG------------------GCSQRCSNLPGS YRCLCEDGYFMHSNKRDCGDINECV----------------------------------- ------------------------------------------LNPNICGT---------- ------------------------------------------------------------ -------------------------ATCKNTLGKYECECAEGYMYNPTSKNCEDIDECAE NVCAQLCVNSPGSYSCYCDGKKGFKLSKDMKNCESVTACI---PLNLEKNYELL------ YLAEQFIGIPVLYLKFKLPNIT--------RFMAEFDFRTYDAEGVILYAESLDNTAWIL LALR-DGKIE----IQYKNEFGTKVTSGGKAINDGLWHI---ISVEELEHSISVKIAKEA VMSINSPGTLFKQSQGFLETKVYIAGLPRKVG-NTLVKQINPRLDGCIRAWNLMNQGHSG VKEVIQEKQSKHCLVAVERGSFYPGTGMAKFQINY--NNLDS-AEDWL-INVTMTIRPST DTGVMF----ALVSN-ETVPLA----LSIVDSNSSDSQKIIVTIGNTTVAQLESKKLCTP RKVMVGLLVTKEQLELSVDSHT----DRSNSE------KLSVLHQAIMANVV--TYLGGL P-DVPLGATLVTAFYNGCME------VKINNRELDLDEAISKHNDIRSHSCPLIMQ---- --------- >XP_005674861.1 PREDICTED: vitamin K-dependent protein S [Capra hircus] ---------MRVLGGLT-GTLLTCLALVL--PVL----EAN------------------- -------------FLSRQHASQVLVRRRRANSLLEETKKGNLERECIEELCNKEEAREVF ENNPETEYFYPKYLGC----------LGSFRAGLFT-TARLSTNAYPDLRSCVN------ -----AIPDQCNPLPCNE-DGYMTCK-DGQATFTCIC----------------------- -----------------------------------------------------------K SGWQGEK-------CES--DINECKD---------------------------------- ------------------------------------------------------------ ------------------------PVNVNG------------------GCSQICENTPGS YHCSCKNGFVMLSNKKDCKDVDECV----------------------------------- ------------------------------------------LKPSICGT---------- ------------------------------------------------------------ -------------------------AVCKNIPGDFECECAEGYKYNPISKSCDDVDECSE NLCAQLCVNYPGGYSCYCDGKKGFKLAQDQKSCEAVPVCL---PLNLEKNYELL------ YLAEQFVGV-VLYLKFRLPETT--------RFSAEFDFRTYDSEGVILYAESSDHSSWFL IALR-EGKIE----IQFKNEKTVKMTTGGKVINDGLWNM---VSVEELEQSISVKIAKEA VMNINKPESLFKPTNGFLETKVYFAGVPRKVE-NALIRPINPRLDGCIRGWNLMNQGTSG VKEIIQEKQNKHCLITVERGSYYPGTGVAQFSIDY--KNESN-PEAWQ-INVSLNIRPSA GTGVML----ALVSS-NTVPFA----LSLVDSATEKLQDILVSVESMVIARIEAESLCSD QQTFLEIRVNRNNLELLTQLRK----DSFHSE--DFQRQFAILDEAMKGTVA--TYLGGL P-DVPFSATPVNAFYQGCME------VNINGVQLDLDEAISKHNDIRAHSCPSVWQNIEH T-------- >XP_025070223.1 vitamin K-dependent protein S isoform X1 [Alligator sinensis] ---------MCLVSTQL-LWGHGQLMPPES-GAA---PAEA------------------- -------------VLSQQHASEYLVRKRRANSFMEESKKGNLERECVEELCNKEEAREIF ENDPETEYFYPKYIRC----------LTYTRLGISS-VSVMSPDSSSDLRTCVT------ -----EISNQCTPLPCNE-NGYTKCI-DGKAAYTCVC----------------------- -----------------------------------------------------------K QGWQGER-------CEE--DIDECQD---------------------------------- ------------------------------------------------------------ ------------------------QENING------------------GCSQTCINLHGS YRCFCEDGYYMLPNKKDCRDWDECM----------------------------------- ------------------------------------------LRPNICGT---------- ------------------------------------------------------------ -------------------------AKCQNTPGKYECVCAEGFRYNSTTKNCEDVDECAE NICAQMCVNYKGSYACHCDGHKGFKLSQDMKTCEAVPVCL---PLNLEPNYQLL------ YLAEQTTENAVLHLRFKLPNAS--------RFSAEFDFRTYDNEGVILYAESSNNTGWFL LALR-DGKIE----IQFKNEHGTKVTSGGKAINDGVWQT---ISVEELEHSICVKIAREA VMSIKSPGNLFKQINGSLEIKVYVAGLPPKVG-NTLIKQINPRVDGCARALNLMSQGHLG LTEVIKKTQIKRCLPSVGKGSYYPGTGVAKFHINY--NNDTN-TGEWV-INVALNIRPSK GTGVMF----ALVSG-ESVPLA----LSIVDSSSSNSQAIIVTIGNIIIARLESKRFCTT RRTLVGFSASKQQIELSVDSQT----DVTNSE-----QELSILDQAMRGTVAVYTYLGGL P-DLPLGITPLTVFYNGCME------AKVNSKELDLDQAAYKHSDIRSHSCPQVIGEDQF FK------- >XP_019331954.1 PREDICTED: vitamin K-dependent protein S [Alligator mississippiensis] ---------MRPLAGG------GCLLVLL--ALA---EARV------------------- -------------FLSQQHASEYLVRKRRANSFMEESKKGNLERECVEELCNKEEAREIF ENDPETEYFYPKYIRC----------LTYTRLGISS-VSVMSPDSSSDLRTCVT------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------DWDECM----------------------------------- ------------------------------------------LRPNICGT---------- ------------------------------------------------------------ -------------------------AKCQNTPGKYECVCAEGFRYNSTTKNCEDVDECAE NICAQMCVNYEGSYTCHCDGHKGFKLSQDMKTCEAVPVCL---PLNLEPNYQLL------ YLAEQTTENAVLHLRFKLPNAS--------RFSAEFDFRTYDNEGVILYAESSNNTGWFL LALR-DGKIE----IQFKNEHGTKVTSGGKAINDGVWQT---ISVEELEHSICVKIAREA VMSIKSPGNLFKQINGSLEIKVYVAGLPPKVG-NTLIKQINPRIDGCARALNLMSQGHLG LTEVIKKTQIKRCLPSVGKGSYYPGTGVAKFHINY--NNDTN-TGEWV-INVALNIRPSK GTGVMF----ALVSG-ESVPLA----LSIVDSSSPNSQAIVVTVGNIIIARLESKRFCTT RRTLVGFSASKQQIELTVDSQT----DVTNSE-----QELSILDQAMRGAVAVYTYLGGL P-DLPLGITPLTVFYNGCME------AKVNSKELDLDQAAYKHSDIRSHSCPQVIGEDQF FK------- >XP_015809320.1 PREDICTED: vitamin K-dependent protein S [Nothobranchius furzeri] ---------M---KRAL-GRPLACLMFLV--TLL---DADR------------------- -------------FLSQNTASQFLSRHRRANTMFEESKKGNLERECIEELCNKEEAREIF ENQPETEYFYPRYVGC----------LGSHRVGINN--QNSDSNIPSDLRTCVKGEKPHL RIWPISTNNSQDPFPNPKAQGSYPLIPRGEPQHTKLI------------LK--------- -----------------------------------------------------------S ISYKEVRMFENLLKCVYLADIDECSD---------------------------------- ------------------------------------------------------------ ------------------------P-DFPA------------------GCNQKCLNIPGS FHCMCEDGYF-LNDNIHCVDVNECL----------------------------------- ------------------------------------------LFPSICEK---------- -------------------P---------------------------------------- -------------------------AKCVNAPGMYECQCPLGFKYTSTSRTCDDVDECEL GLCDDMCHNTIGSFTCHCDGRAGLRLAADERRCESIPVCV---ELNDYKHPEML------ FLGEQFAGLPVIYLRFRLPEST--------KFAAEFDFRTFDPEGVVLYAESSQGS-WFM LGLR-EGRIE----VQFKNQHTSKVTSGGKAINDGQWHV---ISVDELKNSISVKISKEA VMSINSPESLFTSVNGKLETKFYIAGLPNRTE-N-IIKPINPRLDGCIRGWNLMNQGASG VKEVIQEKKSKHCFVHVERGSFFSGAGLAHFNVDY--R---D-SGSWN-VDLKMNIRPSS STGVLF----ALVYN-NTIPLS----VAVLTKEEEDA-NLQVFLDGVSVATLDSLMLCYP DRLTVHLNVTPTELQISANSST-----VSYMTSDALQEALELLNRTMQNPVN--TYVGGI PDDIPLPLTPVSAFYHGCMD------ITVNDRQLDFDEALSKHNSIKSHSCPPVSQTHR- -DVLHFPRE >XP_020745047.1 vitamin K-dependent protein S [Odocoileus virginianus texanus] ---------------------------------------MA------------------- -------------VLSRQHASQVLVRRRRANSLLEETKKGNLERECIEELCNKEEAREVF ENNPETEYFYPKYLGC----------LGSFRAGLFT-TARLSTNTYPDLRSCVN------ -----AIPDQCNPLPCNE-DGYLSCK-DGQATFTCIC----------------------- -----------------------------------------------------------K SGWQGEK-------CES--DINECKD---------------------------------- ------------------------------------------------------------ ------------------------PANVNG------------------GCSQICENTPGS YHCSCKNGFVMLSNKKDCKDVDECV----------------------------------- ------------------------------------------LKPSICGT---------- ------------------------------------------------------------ -------------------------AVCKNIPGDFECECAEGYKYNPVSKSCDDVDECSE NLCAQLCVNYPGGYSCYCDGKKGFKLAQDQKSCEAVPVCL---PLDLDKNYELL------ YLAEQFVGV-VLYLKFRLPETT--------RFSAEFDFRTYDSEGVILYAESSDHSAWFL IALR-EGKIE----IQFKNENTVKMTTGGKVINDGLWNM---VSVEELEQSISVKIAKEA VMNINKPESLFKPTNGFLETKVYFAGIPRKLE-NALIRPINPRLDGCIRGWNLMNQGTSG VKEIIQEKQNKHCLVTVERGSYYPGTGVAQFSIDY--KNESN-PEAWQ-INASLNIRPSA GTGVML----ALVSG-DTVPFA----LSLVDSATEKLQDILVSVESTVIARIQAISLCSD QQTFLEIRINRNNLELSTQLTK----DSFHSE--DFQRQFALLDEAMKGTVA--TYLGGL P-DVPFSATPVNAFYQGCME------VNINGVQLDLDEAISKHNDIRAHSCPSVWQKTKQ T-------- >XP_030271164.1 vitamin K-dependent protein S [Sparus aurata] ---------MWIKKRAL-GESLACLVFLV--TLA---DAYR------------------- -------------FLSQTTAAQFLSRHKRANSLFEEHKKGNLERECIEELCNKEEAREIF ENQPETEYFYPKYVVC----------LGSHRVGINN--QNSNSGIPSDLRTCVT------ -----EISNQCTPYPCYK-EGSENCV-DGQASFTCVC----------------------- -----------------------------------------------------------K PGWKGPR-------CED--DINECID---------------------------------- ------------------------------------------------------------ ------------------------P-EYPA------------------GCDQKCHNLPGS FQCLCEDGYF-ISNKINCVDINECI----------------------------------- ------------------------------------------LFPSSCEE---------- -------------------P---------------------------------------- -------------------------AKCVNTPGMYECQCPQGFKYNFTSRTCNDVDECEF NVCDGTCINTEGSYSCHCDGRQGLRLAEDKRYCEQIPVCV---DLYDHKHPEML------ YLGEQFAGLPVIYLRFRLPENT--------KFAAEFDFRTFDPEGVVLYAESSQDS-WFM LGLR-GGRIE----VQFKNQHTFKVTSGGKAINDGQWHV---ISVDELESSISVKISKEA VMSINSPESLFTSVNGKLETKVYIAGLPNRTD-N-VIKPINPRLDGCIRGWNLMNQGASG VKEVIQEKKSKHCFVYVERGSFFTGVGLAQFNINY--S---D-SGRWN-VDVHMNIRPSS STGVIF----ALVYN-NTVPLS----IAVVTQGEGEA-NLQVFLDGISVATLDSIMLCYP DRLTVHLNVTPTEIQISANSST-----VTYMKSDDLLKALERLNTTMQNPIS--TYVGGI PEDVPLPATPVMAFYHGCME------ISINDQQLDFDEALSKHNSIKSHSCPPVSAPDSR PDAPHPHRE >XP_040194662.1 vitamin K-dependent protein S [Rana temporaria] ---------MMLLSSFC-LILLASTLLMT--TLS---EGRT------------------- -------------FLSSQSASQFLTRKRRANSFFEESKGGDLERECIEELCNKEEAREIF ENAPETEFFYPRYLAC----------LGSHRNGNANKLSYLDYDGPADLRSCVT------ -----ALPDQCKPMPCHK-EGYKECK-DGKGNYTCVC----------------------- -----------------------------------------------------------K PGWQGVR-------CNE--DINECED---------------------------------- ------------------------------------------------------------ ------------------------PEKENA------------------GCSQRCVNFPGG YRCACEDGYYLLADKHTCNDRNECE----------------------------------- ------------------------------------------LSPVICGG---------- ------------------------------------------------------------ -------------------------AKCRNTPGKYECDCNSGYRFNTSSKTCEDVDECAE DVCSQMCVNMPGSYKCYCEGRKRFKLAGDKKSCERIPTCV---PLNLETNYELL------ YLAEQFTGIPVVYLRFKLPDVT--------RFSAEFDFRTYDGEGVILYAESADATSWFL LALR-DGKIE----IQFKNDLWTKVTTGGKSINNGDWHI---VSVEELENSISVKIAKEA VMNINNPKYLFKPVNGILETKVYIAGLPRKIE-N-LIKPINPRLDGCIRGWNLMNQGALG VKEFIQGKQSKHCLVDVEEGSYYPGGGLAHFKLNY--TDITSIEEDWI-VNVTLDIRSST GTGVMF----ALVKE-DTVPLA----IAIEDQSSDIVQDIIVSIKGITVARLSTKRICTD KNLFVGITATKSALDITSDSYT----EIRYANKEEMKTQLSVLDQEMKGQLD--TYLGGI P-DIPPTATPVSAFYIGCMD------VAINGNLIDLDEAVSKQNDIRSHSCPLIS----- --------- >XP_039251316.1 vitamin K-dependent protein S-like [Styela clava] M--------LNVMKLKI-VLLLHILLGVNE-GIS----DSP------------------- -------------FIDRKEASRFLGRTKRSNSFWEEIKSGNQERECIEEDCSMEEAYEVF DNNFKANQFWKKYLRCNQALPRRYKQQGKIRIARQ--ASRRSERENVKLRACIS------ -----D-EDQCNPFPCVR-SNTAECV-DTVSSFKCVCKNGFAGRKCESPLNECLSNPCQN SAICEDEIGGFTCFCDSNHEGIFCEIEVNDCRNTVEKQCSAVGGICQQRDAGDAYTCVCN PGYQGEL-------CKH--DVDECLNSTSCEQECHNTVGSFTCTCGHGFLIDTTTRTTCK DIDECNDVSHGCISQDFCHNTPGSFYCTCKHGFQLDETYRRYCDDIDECADENGGCPIIE GGCGLNGKTCKTCNNFDGGFNCYCPSGFNSYVEGGDCTDINECESSYHGCQQKCENFPGG YRCLCSEGYMLNFNGKTCSDINECLKDHGCSYRCSNNVGSYYCTCKRGFELDDDQRTCID TDECQGVTKCDQTCINTDGGYKCGCNPGYRLLGKYKCSEIDECRPRPCGNNGNCIDEVNG YRCECFEGFTGKLCDVGTDPCAGDPCLNSGVCSAFDSGYVCRCAHGYIGPRCQTKHIEMC EIGYRREDGQCIDIDECAETTGLCQQICHNTKGSYTCTCDAGF--NMNGLNCEDIDECLN SPCQQVCTNSIGSYDCSCS--EGYSLNESDDTCEELFACVGNSPQMLPEKHFLLGTRKID YISQTF-----------VESSS--------SFQIGFDFRTFDTDGMLVAVVCSDVEQHYI FLLHADGQLTLAAFVSWPPKIEITKPKNALVLSDGQWHS---IILRKRKNRVTVMEGKNK LLDLKFMKNKFGSAG-----QIYYGGIPGDVTVPTTIRDTDLYFQGCLKG--NYTHGFTI AGDSKMPGIHNGCFESIEKGMYFDGSGFLHQSVEL--QT--------N-LRMRFEFKSLS AQGVIIFAEDALRSR-FSVTIAGNQIIASLTTSRNET-------RSSTFTTSNGELLCDQ IWHICDFTITSNMVRLHVDGVAAGQDNISDSK-----------RVQFTGLVD--LYIGGR P-----GATSRSSYTGSLRN------IKINRKDLSLDN-IVEMNGVRLHSIPAL------ ---------
BMGE Cleaned alignment of selected proteins >sp|P07225|PROS_HUMAN Vitamin K-dependent protein S OS=Homo sapiens OX=9606 GN=PROS1 PE=1 SV=1 MRVLGGRCGALLACLLLVLFLSKQQASQVLVRKRRANSLLEETKQGNLERECIEELCNKEEAREVFENDPETDYFYPKYLVCLRSFQTGLFTAARQSTNAYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKDINECKDPSNINGGCSQICDNTPGSYHCSCKNGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPLNLDTKYELLYLAEQFAGVVLYLKFRLPEISRFSAEFDFRTYDSEGVILYAESIDHSAWLLIALRGGKIEVQLKNEHTSKITTGGDVINNGLWNMVSVEELEHSISIKIAKEAVMDINKPGPLFKPENGLLETKVYFAGFPRKVESELIKPINPRLDGCIRSWNLMKQGASGIKEIIQEKQNKHCLVTVEKGSYYPGSGIAQFHIDYNNVSSAEGWHVNVTLNIRPSTGTGVMLALVSGNTVPFAVSLVDSTSEKSQDILLSVENTVIYRIQALSLCSDQQHLEFRVNRNNLELSTPLKETISHEDLQRQLAVLDKAMKAKVATYLGGLPDVPFSATPVNAFYNGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVW >tr|F1QK29|F1QK29_DANRE Vitamin K-dependent protein S OS=Danio rerio OX=7955 GN=pros1 PE=4 SV=1 MRSLKAACGSELGLLLLLLFLPQSKASEFLLRHRRANTLFEESKKGNLERECIEELCNKEEAREIFENNLETEYFYPRYVVCLGSHRVGINN---PEPGIPQNLRTCVEEISNQCLPPPCYKEGSERCVDGQGSYRCVCKPGWRGQRDIDECEDP-EFPAGCSQTCFNLPGSFTCGCESGYY-TNDGVHCIDIDECVLFPSVCVESKCINAPGTFECRCQLGYTYNMSSHTCVDVDECLEDACAGECVNAVGSFSCQCDGRRGLQLDEDGLGCVSIPQCLQLYDHKHKEMLYLGEQFSGLVIYLRFRLQPHTRFAAEFDFRTFDPEGVILYAESSPDS-WIMLGLRSGRIEVQFKNEHSIKMTSGGKAINDGQWHVISVEELSGSISVKISKEAVMSINSPERLFTPVNDKLETKVYIAGLPNHNQS-LIKTINPRLDGCIRGWNLMNQGASGVKEVIQEKESKHCYVHVEKGSFFSGGGHALFNIDYS---VSGQWKLDVVMSLRPSSTTGVILALVSNNTVPLLVAVVSLGPDDA-ELQVLLDGVCVATLQSLMLCYPDRVVELRASAEGLQISANSS-VSYSETLSAALHKLDTAMHTQPQTYIGGLPDLPLSITPVSAFYHGCLELVIGGRQLDFDEAVSKDNSIKSHSCPPYS >NP_035303.1 vitamin K-dependent protein S preproprotein [Mus musculus] MRVLSARFRVLLACLALVIFLSKERASQVLVRKRRANTLFEETMKGNLERECIEELCNKEEAREVFENNPETDYFYPKYLGCLGAFRVGSFHAARQSANAYPDLRSCVKAISDQCDPIPCNEDGYLACQDGQAAFTCFCKPGWQGDRDVNECKDPSNVNGGCSQICDNTPGSYHCSCKRGFAMLPNKKDCKDLDECALKPSVCGTAVCKNIPGDFECECPDGYRYDPSSKSCKDVDECSENMCAQLCVNFPGGYSCYCDGKKGFKLAQDQKSCEGIPVCLSLDLDKNYELLYLAEQFAGVVLYLKFRLPDITRFSAEFDFRTYDSEGIILYAESLDHSNWLLIALRDGKIEVQFKNEFSTQITTGGNVINNGIWNMVSVEELDDSVSIKIAKEAVMNINKLGSLFKPTDGFLDTKIYFAGLPRKVESALIKPINPRLDGCIRGWNLMKQGALGAKEIIEGKQNKHCFLNVEKGSYYPGSGIAQFSIDYNNVTNAEGWQMNVTLNIRPSTGTGVMLALVSGGTVPFALSLVDSRSGTSQDIVVFVENSVVARLEAVSLCSDQQQLKCNVNRNGLELWTPLRDVIYSKDLQRQLAVLDKAMKRTVATYLGGIPDISFSATPVNAFYSGCMEVNINGVQLDLDEAISKHKDIRAHSCPSVR >NP_112348.2 vitamin K-dependent protein S precursor [Rattus norvegicus] MRVLSVRFRVLLACLALVLFLSKERASQVLVRKRRANTLLEETKKGNLERECIEELCNKEEAREVFENNPETDYFYPKYLGCLGAFRVGAFSAARQSANAYPDLRSCVNAIPDQCDPMPCNEDGYLSCKDGQGAFTCICKPGWQGDKDINECKDPSNINGGCSQTCDNTPGSYHCSCKIGFAMLTNKKDCKDVDECSLKPSVCGTAVCKNIPGDFECECPNGYRYDPSSKSCKDVDECSENTCAQLCVNYPGGYSCYCDGKKGFKLAQDQRSCEGIPVCLSLDLDKNYELLYLAEQFAGVVLYLKFRLPDITRFSAEFDFRTYDSEGIILYAESLDHSNWLLIALREGKIEVQFKNEFSTQITTGGNVINNGIWNMVSVEELDDSVSIKIAKEAVMNINKLGSLFKPTDGFLDTKIYFAGLPRKVESALIKPINPRLDGCIRGWNLMKQGALGAKEIVEGKQNKHCFLTVEKGSYYPGSGIAQFSIDYNNVTNAEGWQINVTLNIRPSTGTGVMLALVSGDTVPFALSLVDSGSGTSQDILVFVENSVAAHLEAITLCSEQPQLKCNINRNGLELWTPVRDVIYSKDLQRQLAILDKTMKGTVATYLGGVPDISFSATPVNAFYSGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVR >NP_776863.1 vitamin K-dependent protein S precursor [Bos taurus] MRVLGGRTGTLLACLALVLFLSRQHASQVLIRRRRANTLLEETKKGNLERECIEELCNKEEAREIFENNPETEYFYPKYLGCLGSFRAGLFTAARLSTNAYPDLRSCVNAISDQCNPLPCNEDGFMTCKDGQATFTCICKSGWQGEKDINECKDPVNINGGCSQICENTPGSYHCSCKNGFVMLSNKKDCKDVDECVLKPSICGTAVCKNIPGDFECECAEGYKYNPVSKSCDDVDECAENLCAQLCVNYPGGYSCYCDGKKGFKLAQDQKSCEAVPVCLPLDLDKNYELLYLAEQFVGVVLYLKFRLPETTRFSAEFDFRTYDSEGVILYAESSDHSAWFLIALREGKIEIQFKNEKTTKMTTGGKVINDGLWHMVSVEELEQSISVKIAKEAVMNINKPGSLFKPTNGFLETKVYFAGVPRKMENALIRPINPRLDGCIRGWNLMNQGTSGVKEIIQEKQNKHCLVNVEKGSYYPGTGVAQFSINYKNESNPEAWQINVSLNIRPSAGTGVMLALVSDNTVPFALSLVDSATEKLQDILVSVESMVIGRIEAISLCSDQQFLEIRVNRNNLELSTQLRDSFHSEDFQRQFAILDEAMKGTVVTYLGGLPDVPFSATPVNAFYQGCMEVNINGVQVDLDEAISKHNDIRAHSCPSVW >XP_020926395.1 vitamin K-dependent protein S [Sus scrofa] MRVLGGRCGALLACLALALFLSKQHASQVLIRKRRANSMLEERKQGNLERECIEELCSKEEAREVFENDPETEYFYPAYLACLGSFRAGLFTAARLSTNAYPDLRSCVNAIPDQCNPLPCNEDGYLTCKDGQAMFTCICKSGWEGEKDINECKDPANINGGCSQICDNTPGSYHCSCKSGFIMLSNKKDCKDVDECSVKPSICGTAVCKNIPGDFECECPEGYRYNPTLKYCEDVDECSENMCAQLCVNYPGGYSCYCDGKRGFKLAQDQKSCEAVPVCLPLNLDKNYELLYLAEQFVGVVLYLKFRLPEITRFSAEFDFRTYDSEGVILYAESSDHSAWFLIALRDGKIEIQFKNEHTTKITTGGRVINDGLWNMVSVEELEQSISVKIAKEAVMNINKPESLFKPTNGFLETKVYFAGLPRKVENALIKPINPRLDGCIRGWNLMNQGASGVKEIIQEKQNKHCLVTVEKGSYYPGSGVAQFSIDYKNVSSAGAWQVNVSLNIRPSAGTGVMLALVSGNTVPFALSLVDSATEKLQDIVVSVENVEIARIKALSLCSSLQLLEMRVSVNSLELLTQFERRISSEDYQGQFAILDKAMEGTVATYLGGLPDVPFSATPVNAFYNGCMDVIINGVPLDLDEAIAKHNDIRAHSCPSVW >XP_043304830.1 vitamin K-dependent protein S [Cervus canadensis] MRVPGGRTGTLLACLALVLFLSRQHASQVLVRRRRANTLLEETKKGNLERECIEELCNKEEAREVFENNPETEYFYPKYLGCLGSFRAGLFTTARLSTNTYPDLRSCVNAIPDQCNPLPCNEDGYLSCKDGQATFTCICKSGWQGEKDINECKDPANVNAGCSQICVNTPGSYHCSCKNGFVMLSNKKDCKDVDECVLKPSICGTAVCKNIPGDFECECAEGYKYNPVSKSCDDVDECSENLCAQLCVNYPGGYSCYCDGKKGFKLAQDQKSCEAVPVCLPLDLDKNYELLYLAEQFVGVVLYLKFRLPETTRFSAEFDFRTYDSEGVILYAESSDHSAWFLIALREGKIEIQFKNENTVKMTTGGKVINDGLWNMVSVEELEQSISVKIAKEAVMNINKPESLFKPTNGFLETKVYFAGIPRKLENALIRPINPRLDGCIRGWNLMNQGTSGVKEIIQEKQNKHCLVTVERGSYYPGTGVAQFSIDYKNESNPEAWQINVSLNIRPSAGTGVMLALVSGDTVPFALCLVDSATEKLQDILVSVESMVIARIQAISLCSDQQFLEIRVNRNNLELLTQLTDSFHSEDFQRQFAILDEAMKGTVATYLGGLPDVPFSATPVNAFYQGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVW >KAB0344409.1 hypothetical protein FD754_021335 [Muntiacus muntjak] LFTVFILFLTLHTWLLYFQVLSRQHASQVLVRRRRANSLLEETKKGNLERECIEELCNKEEAREVFENNPETEYFYPKYLGCLGSFRAGLFTTARLSTNTYPDLRSCVNAIPDQCNPLPCNEDGYLSCKDGQATFTCICKSGWQGEKDINECKDPANVNGGCSQICVNTPGSYHCSCKNGFVMLSNKKDCKDVDECVLKPSICGTAVCKNIPGDFECECAEGYKYNPVSKSCDDVDECSENLCAQLCVNYPGGYSCYCDGKKGFKLAQDQKSCEAVPVCLPLDLDKNYELLYLAEQFVGVVLYLKFRLPETTRFSAEFDFRTYDSEGVILYAESSDHSAWFLIALREGKIEIQFKNENTVKMTTGGKVINDGLWNMVSVEELEQSISVKIAKEAVMNINKPESLFKPTNGFLETKVYFAGIPRKLENALIRPINPRLDGCIRGWNLMNQGTSGVKEIIQEKQNKHCLVTVERGSYYPGTGVAQFSIDYKNESNPEAWQINVSLNIRPSAGTGVMLALVSGDTVPFALSLVDSATEKLQDILVSVESMVIARIQAISLCSDQQFLEIRVNRNNLELLTQLTDSFHSEDFQRQFAILDEAMKGTVATYLGGLPDVPFSATPVNAFYQGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVW >KAF4025963.1 hypothetical protein G4228_018124 [Cervus hanglu yarkandensis] MRVPGGRTGTLLACLALVLFLSRQHASQVLVRRRRANTLLEETKKGNLERECIEELCNKEEAREVFENNPETEYFYPKYL-----------------------------AIPDQCNPLPCNEDGYLSCKDGQATFTCICKSGWQGEKDINECKDPANVNAGCSQICVNTPGSYHCSCKNGFVMLSNKKDCKDVDECVLKPSICGTAVCKNIPGDFECECAEGYKYNPVSKSCDDVDECSENLCAQLCVNYPGGYSCYCDGKKGFKLAQDQKSCEAVPVCLPLDLDKNYELLYLAEQFVGVVLYLKFRLPETTRFSAEFDFRTYDSEGVILYAESSDHSAWFLIALREGKIEIQFKNENTVKMTTGGKVINDGLWNMVSVEELEQSISVKIAKEAVMNINKPESLFKPTNGFLETKVYFAGIPRKLENALIRPINPRLDGCIRGWNLMNQGTSGVKEIIQEKQNKHCLVTVERGSYYPGTGVAQFSIDYKNESNPEAWQINVSLNIRPSAGTGVMLALVSGDTVPFALSLVDSATEKLQDILVSVESMVIARIQAISLCSDQQFLEIRVNRNNLELLTQLTDSFHSEDFQRQFAILDEAMKGTVATYLGGLPDVPFSATPVNAFYQGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVW >XP_018104341.1 vitamin K-dependent protein S isoform X2 [Xenopus laevis] MGLLDKVCLVLLASTLLAVFLSPQHASQFLSRRRRANSFLEESKGGNLERECIEELCNKEEAREIFENVPETEYFFPKYLACLGAHRSGTLSLSYLNFDGPVDLRACVNAIPDQCTPLPCNKERSKECIDGKGNFTCICKPGFQGPLDINECVDPVNPNAGCNQKCLNLPGSYRCACEDGYYMLPNKHTCSDRNECEMFPTICGSAVCKNTPGKYECECDNGYRYNSSAKACEDIDECAVRSCSQICVNNPGGYTCYCDGRRKYKLAQDKTSCESIPVCVPLNLETNYELLFLAEQFTGIVVYLRFKLPDVSRFSAEFDFRTYDGEGVILYAESADSTSWFLLALRDGKIEIQFKNELWTKVTTGGKAINNGEWHIITVEELENIISVKIAKEAVMNINNPRSLFKSSNGILEIKVYIAGLPRKVDN-IIKPINPRLDGCIRGWNLMNQGALGVKEVIQGKQSKHCLVTVERGSYYPGGGVARFIMNYN-VSTNDEWVANITFNIRSSTGIGVMFSLVNGETVPLAIAIEDLGSDFLQGIVVSIHSATVARLTTKRICTDKNLISVSITKNTLVLNANSYDITYASELDKQLSILDQAMQENPDTYLGGIPDIPVAATPVSAHYVGCMDVTINNELMDLDGAVSKQNDIRSHSCPLIL >OWK00463.1 PROS1 [Cervus elaphus hippelaphus] M------------------VLSRQHASQVLVRRRRANTLLEETKKGNLERECIEELCNKEEAREVFENNPETEYFYPKYLGCLGSFRAGLFTTARLSTNTYPDLRSCVNAIPDQCNPLPCNEDGYLSCKDGQATFTCICKSGWQGEKDINECKDPANVNAGCSQICVNTPGSYHCSCKNGFVMLSNKKDCKDVDECVLKPSICGTAVCKNIPGDFECECAEGYKYNPVSKSCDDVDECSENLCAQLCVNYPGGYSCYCDGKKGFKLAQDQKSCEAVPVCLPLDLDKNYELLYLAEQFVGVVLYLKFRLPETTRFSAEFDFRTYDSEGVILYAESSDHSAWFLIALREGKIEIQFKNENTVKMTTGGKVINDGLWNMVSVE----SMSVLWQRKQIHGCHS-------------------GLASTVG----KSLNT---------DAQSEAEAQVRKLEEQRLEKDVWVST-----------ALLTLRWQ----TRNWLVCLHFDWRQTKMKS---EVVLNHIIILM-------------------GINFKFVQKMNLN--------KVKFTSLQKKACSD-------WKPEFTHVPTLLSHNSEDFCSVFPD---SCYLCSTFQEACLPVKQKGRWEQCSDAVSSQGLC---SFPPYL >XP_416641.3 vitamin K-dependent protein S [Gallus gallus] MRPRGGRCVPLLAGLAVALFLSHQYASEFLARKRRANSFMEESKKGNLERECVEELCNKEEAREIFENNPETEYFYPKYLSCLASYRAGVFRVPTVTPDSPANLRVCVSEISNQCSPLPCHRDGYKECIDGQAKYTCICKPGWQGENDINECED---INGGCSQRCSNLPGSYRCLCEDGYFMHSNKRDCRDINECALHPNICGTAVCKNTLGKYECECAEGYKYNSTSKSCEDIDECAENTCAQLCVNSPGSYSCYCDGKKGFKLSKDMKNCESVPVCIPLNLERNYELLYLAEHFTGIVLYLKFKLPNVTRFSAEFDFRTYDSEGIILYAESFDNTAWILLALRDGKIEIQFKNEFGTKVTSGGKAINDGLWHIISVEELENSISVKIAKEAVMNINSPGTLFKQSHGFLETKVYIAGLPDKVGDTLIKQINPRLDGCIRAWNLMNQGHSGVKEVIQEKQSKHCLVTVERGSFYPGTGMAQFDINYNNRDSAEDWLINVTMTIRPSTDTGVMFALVSNETVPLALSIVDSNSSDSQEIIVTIGNITVARLESKKLCTPRKQVGLLVTKQQLQLSVDSRDQSNSE----QLSVLHQAMMTNVVTYLGGLPDVPLGATLVTAFYNGCMEVKVNSRQLDLDEAISKHNSIRSHSCPLIM >XP_516603.3 vitamin K-dependent protein S [Pan troglodytes] MRVLGGRCGALLACLLLVLFLSKQQASQILVRKRRANSLLEETKQGNLERECIEELCNKEEAREVFENDPETDYFYPKYLVCLRSFQTGLFTAARQSTNAYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKDINECKDPSNINGGCSQICDNTPGSYHCSCKSGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPLNLNTKYELLYLAEQFAGVVLYLKFRLPEISRFSAEFDFRTYDSEGVILYAESIDHSAWLLIALRGGKIEVQLKNEHTSKITTGGDVINNGLWNMVSVEELEHSISIKIAKEAVMDINKPGPLFKPENGLLETKVYFAGFPRKVESELIKPINPRLDGCIRSWNLMKQGASGIKEIIQEKQNKHCLVTVEKGSYYPGSGIAQFHIDYNNVSGAEGWHVNVTLNIRPSTGTGVMLALVSGNTVPFAVSLVDSTSEKSQDILLSVENTVIYRIQALSLCSDQQHLEFRVNRNNLELSTPLKETISHEDLQRQLAVLDKAMKAKVATYLGGLPDVPFSATPVNAFYNGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVW >XP_038300575.1 vitamin K-dependent protein S isoform X1 [Canis lupus familiaris] MRLLAGRCGALLACLVLVLFLSKEHASQVLVRKRRANSMFEETKKGNLERECIEELCNKEEAREIFENDPETDYFYPKYLGCLGSFRAGLFTAARLSTDAYPDLRSCVTAIPDQCSPLPCNEDGYKTCRDGQATFTCICKPGWQGDRDINECKDPSNINGGCSQMCDNTPGSYHCSCKSGFVMLLNKKDCKDVDECSIMPDICGAAVCKNIPGDYECECAEGYRYNPALKSCEDVDECSENLCAQLCVNYPGGYSCYCDGRKGFKLAQDHKSCEAVPVCLPLNLDKNYELLYLAEQFVGVVLYLKFRLPEITRFSAEFDFRTYDSEGVILYAESLDRSAWFLIALRDGKIEIQFKNEFTTKITTGGKAINNGLWNTVSVEELEYSISIKIAKEAVMNINKPGRLFKPSNGFLETKVYFAGLPRKVENVLIRPINPRLDGCIRGWNLMNQGASGVKEIIQEKQNKHCLVTVEKGSYYPGSGVAVFGIDYDSDSAAGAWQLNASLSVRASAGTGVLLALVSGSSVPLALSLADSISETLQDILVSVENIVISRIEAVNLCSNQQHLELKVNRNNLELSTPVKDTISSEDLPQQFASLDKAMKGTVTTYLGGLPDIPFGATPVNVFYNGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVL >XP_002716802.1 PREDICTED: vitamin K-dependent protein S [Oryctolagus cuniculus] MRVLGGRCGALLACLALVLFLTKQHASQVLVRKRRANSMLEETKKGNLERECIEELCNKEEAREVFENDPETDYFYPKYLGCLGSFRAKLFTATRRSANPYPDLRSCVNAIPDQCNPLPCSEEGYLNCKDGQATFTCICKPGWQGEKDINECKDPTNINGGCSQICDNTAGSYHCSCKSGFVMLANEKDCKDMDECSVKPSVCGTAVCKNTPGDFECECSEGYRYNPTAKSCEDIDECSENMCAQLCVNYPGGYSCYCDGKKGFKLAQDKKSCEAVPVCLPLDLDKNYQLLYLAEQFVGAVLYLKFHLPEITRFSAEFDFRTYDSEGVILYAESLDHSTWFLIALRQGKIEIQFKNDYAAQITTGGQVINDGLWNMVSVEELEHSVSIKIAQEPVMNINKPGSLFKPTNGFLETKVYFAGLPRKVENALIRPINPRLDGCMRGWNLMKQGASGVKEIIQQKQKKHCLVTVEKGSYYPGSGIAQFHIDYNNLSYVEDWQVNVTLKIRPSTGTGVMLALVSGNTVPFALSLVQSTSETSQDILVSVENRVIYQLESISLCSGQQQLEFSVSRNHLELSTPLVDVIYSEDLQRHLAVLDEAMKGTVTTYLGGLPDVPFNATPVNAFYNGCMEVNINGVQLDLDEAVSKHNDIRAHSCPSVW >XP_024100978.1 vitamin K-dependent protein S isoform X1 [Pongo abelii] MRVPGGRCWALLACLLLVLFLSKQQASQVLVRKRRANSLLEETKQGNLERECIEELCNKEEAREVFENDPETDYFYPKYLVCLRSFQTGLFTAARQSTNAYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKDINECKDPSNINGGCSQICDNTPGSYHCSCKSGFVMLSNKKDCKDVDECSLKISVCGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSESMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPLNLDTKYELLYLAEQFAGVVLYLKFRLPEISRFSAEFDFRTYDSEGVILYAESIDHSAWLLIALRGGKIEVQLKNEHTSKITTGGDVINNGLWNMVSVEELEHSISIKIAKEAVMDINKPGPLFKPENGLLETKVYFAGFPRKVESELIKPINPRLDGCIRSWNLMKQGASGIKEIIQEKQNKHCLVTVEKGSYYPGSGIAQFHIDYNNVSSAEGWHINVTLNIRPSMGTGVMLALVSGSTVPFAVSLVDSTSEKSQDILLSVENTVIYRIQALSLCSDQQHLEFRVNRNNLELSTPLKETISHEDLQRQLAVLDKAMKAKVATYLGGLPDVPFSATPVNAFYNGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVW >XP_019475114.1 vitamin K-dependent protein S [Meleagris gallopavo] ---------------------------------------MEESKKGNLERECIEELCNKEEAREIFENNPETEYFYPKYLSCLASYRAGVFRVTAVTPDSPADLRACVNEISNQCSPLPCHRDGYKDCIDGQARYTCICKPGWQGENDINECED---FNGGCSQRCSNLPGSYRCLCEDGYFMHSNKRDCRDINECALHPNICGTAVCKNTLGKYECECAEGYTYNSTSKNCEDIDECAENTCAQLCVNSPGSYSCYCDGKKGFKLSKDMKNCESISACIPLNLERNYELLYLAEQFTGIVLYLKFKLPNVTRFSAEFDFRTYDSEGVILYAESLDNTAWILLALRDGKIEIQFKNEFGTKVTSGGKAINDGLWHIISVEELENSISVKIAKEAVMNINSPGTLFKQSHGFLETKVYIAGLPRKVGDSLIKQINPRLDGCIRAWNLMNQGHSGVKEVIQEKQSKHCLVTVERGSFYPGTGMAKFHINYNNLDSAEDWLINVTMTIRPSTDTGVMFALVSNETVPLALSIVDSNSSDSQEIIVTIGNITVASLESKKLCTPRKQVGLLVTKQQLQLSVDSRDQSNSE----QLSVLHQAMMTNVVTYLGGLPDVPLGATLVTAFYNGCMEVKVNSRQLDLDEAILKHNSIRSHSCPLIM >XP_034812860.1 vitamin K-dependent protein S isoform X1 [Pan paniscus] MRVLGGRCGALLACLLLVLFLSKQQASQILVRKRRANSLLEETKQGNLERECIEELCNKEEAREVFENDPETDYFYPKYLVCLRSFQTGLFTAARQSTNAYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKDINECKDPSNINGGCSQICDNTPGSYHCSCKSGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPLNLDTKYELLYLAEQFAGVVLYLKFRLPEISRFSAEFDFRTYDSEGVILYAESIDHSAWLLIALRGGKIEVQLKNEHTSKITTGGDVINNGLWNMVSVEELEHSISIKIAKEAVMDINKPGPLFKPENGLLETKVYFAGFPRKVESELIKPINPRLDGCIRSWNLMKQGASGIKEIIQEKQNKHCLVTVEKGSYYPGSGIAQFHIDYNNVSSAEGWHVNVTLNIRPSTGTGVMLALVSGNTVPFAVSLVDSTSEKSQDILLSVENTVIYRIQALSLCSDQQHLEFRVNRNNLELSTPLKETISHEDLQRQLAVLDKAMKAKVATYLGGLPDVPFSATPVNAFYNGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVW >XP_023094643.1 vitamin K-dependent protein S isoform X1 [Felis catus] QLLNESRPSSLLIQMFPGLVLSKQHASQVLIRKRRANSMFEETKKGNLERECIEELCNKEEAREIFENNPETDYFYPKYLDCLGSFRAGLFTAARQSTDAYPDLRSCVTAIPDQCSPLPCNEDGYMSCKDGQATFTCVCKSGWQGDKDINECKDPSNVNGGCSQICDNTPGSYHCSCKSGFVMLSNKKDCKDVDECSMKPDICGTAVCKNIPGDFECECAEGYRYNPTLKSCEDVDECSENMCAQLCVNYPGGYSCYCDGKKGFKLAQDHRSCEAVPVCLPLNLDKNYELLYLAEQFVGVVLYLKFRLPEITRFSAEFDFRTYDSEGVILYAESLDHSCWFLIALRDGKIEIQFKNEYATKITTGGKVINNGLWNTVSVEELEYSISVKIAKEAVMNINKPRSLFKPANGFLETKVYFAGLPRKGENVLIKPINPRLDGCIRGWNLMNQGASGVKEIIQEKQNKHCLVTVEKGSYYPGSGVALFSIDYNNISNAEGWQVNVSLNIRPSAGTGVMFALVSGYTVPFALSLVDSASEKLQDILVSVENMVVSRVEAISLCSNEQHLEVRVNRTSLELLTPLKDIIYSEDLQSQLAILDIAMKERVSTYLGGLPDIPFSATPVNAFYNGCMEMSINGVQLDLDEAISKHNDIRAHSCPSVL >XP_004002896.2 vitamin K-dependent protein S [Ovis aries] MRVLGGLTGTLLTCLALVLFLSRQHASQVLVRRRRANSLLEETKKGNLERECIEELCNKEEAREVFENNPETEYFYPKYLGCLGSFRAGLFTTARLSTNAYPDLRSCVNAIPDQCNPLPCNEDGYMTCKDGQATFTCICKSGWQGEKDINECKDPVNVNGGCSQICENTPGSYHCSCKNGFIMLSNKKDCKDVDECVLKPSICGTAVCKNIPGDFECECAEGYKYNPVSKSCDDVDECSENLCAQLCVNYPGGYSCYCDGKKGFKLAQDQKSCEAVPVCLPLNLEKNYELLYLAEQFVGVVLYLKFRLPETTRFSAEFDFRTYDSEGVILYAESSDHSSWFLIALREGKIEIQFKNEKTVKMTTGGKVINDGLWNMVSVEELEQSISVKIAKEAVMNINKPESLFKPTNGFLETKVYFAGVPRKVENALIRPINPRLDGCIRGWNLMNQGTSGVKEIIQEKQNKHCLITVERGSYYPGTGVAQFSIDYKNESNPEAWQINVSLNIRPSAGTGVMLALVSGNTVPFALSLVDSATEKLQDILVSVESMVIARIEAETLCSDQQFLEIRVNRNNLELLTQLRDSFHSEDFQRQFAILDEAMKGTVATYLGGLPDVPFSATPVNAFYQGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVW >XP_030865634.1 vitamin K-dependent protein S [Gorilla gorilla gorilla] MRVQGGRCGALLACLLLVLFFSKQQASQVLVRKRRANSLLEETKQGNLERECIEELCNKEEAREVFENDPETDYFYPKYLVCLRSFQTGLFTAARQSTNAYPDLRSCVNAIPDQCSPLPCNEDGYMSCKDGKASFTCTCKPGWQGEKDINECKDPPNINGGCSQICDNIPGSYHCSCKSGFVMLSNKKDCKDVDECSLKPSICGTAVCKNIPGDFECECPEGYRYNLKSKSCEDIDECSENMCAQLCVNYPGGYTCYCDGKKGFKLAQDQKSCEVVSVCLPLNLDTKYELLYLAEQFAGVVLYLKFRLPEISRFSAEFDFRTYDSEGVILYAESVDHSAWLLIALRGGKIEVQLKNEHTSKITTGGDVINNGLWNMVSVEELEHSISIKIAKEAVMDINKPGPLFKPENGLLETKVYFAGFPQKVESELIKPINPRLDGCIRSWNLMKQGASGIKEIIQEKQNKHCLVTVEKGSYYPGSGIAQFHIDYNNVSSAEGWHVNVTLNIRPSTGTGVMLALVSGNTVPFAVSLVDSTSEKSQDILLSVENTVIYRIQAPSLCSDQQHLEFRVNRNNLELSTPLKETISHEDLQRQLAVLDKAMKAKVATYLGGLPDVPFSATPVNAFYNGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVW >XP_011488632.1 vitamin K-dependent protein S isoform X1 [Oryzias latipes] MPVPRRILGRALAFFVLLVFLSQNTASQFLRRHRRANSGFEETKAGNLERECIEELCNKEEAREIFENQPETEYFYPKYVVCLGSHRVGISN-GNSGSDIPSNLRTCVKEISNQCTPFPCYKEGSEGCVDGQASFTCVCKPGWKGRLDIDECSDP-DFPAGCKHKCNNIPGSFYCMCDEGYF-LNDKINCVDINECLLYRSICEEAKCVNTPGMYECQCPPGFKYNFTSKSCDDVNECERVLCDGTCVNTVGSYTCICDGRAGLRLAVDDRYCETIPICVDLNDYKHPEMLYLGELFAGRVILLHFRLPENTKFAAEFDFRTFDPEGVILYAESSNHS-WFMLGLRGGRIEVQFKNHHAFKVTSGGKFINDGEWHVISVDELENSISVKISNEAVMSINSPESLFTSVNGKLETKVYIAGLPNRTNN-VIKPINPRLDGCIRGWNFMKQGPSGVKEIIQGKQSKHCFVHVERGSFFSGEGLAHFDIDYTG--KSGKWNVNVEMRIRPSKSTGVLFALVYNNTVPLSVAVVEKGEGDA-NLQVFLEGVSVATLDSLMLCYPERGIQLNVTPSEIQLSASSS-VSYIKVLEKKLEVLNITMQNPVGTYIGGIPNIPLIATPVSAFYYGCMEITINDQWLDFDEAHRKHNSIKSHSCPPVS >XP_021143422.1 vitamin K-dependent protein S isoform X1 [Columba livia] M------------------VLSQQYASQFLVRKRRANSFMEESKKGNLERECIEELCNKEEAREIFENNPETEYFYPKYLSCLASHRAGVFRVTAVTPDSPDDLRVCVNEISNQCSPLPCHKDGYKDCIDGQAKYTCICKPGWQGEKDINECED---LNGGCSQRCSNLPGSYRCLCEDGYFMHSNKRDCGDINECVLNPNICGTATCKNTLGKYECECAEGYMYNPTSKNCEDIDECAENVCAQLCVNSPGSYSCYCDGKKGFKLSKDMKNCESVTACIPLNLEKNYELLYLAEQFIGIVLYLKFKLPNITRFMAEFDFRTYDAEGVILYAESLDNTAWILLALRDGKIEIQYKNEFGTKVTSGGKAINDGLWHIISVEELEHSISVKIAKEAVMSINSPGTLFKQSQGFLETKVYIAGLPRKVGNTLVKQINPRLDGCIRAWNLMNQGHSGVKEVIQEKQSKHCLVAVERGSFYPGTGMAKFQINYNNLDSAEDWLINVTMTIRPSTDTGVMFALVSNETVPLALSIVDSNSSDSQKIIVTIGNTTVAQLESKKLCTPRKMVGLLVTKEQLELSVDSHDRSNSE----KLSVLHQAIMANVVTYLGGLPDVPLGATLVTAFYNGCMEVKINNRELDLDEAISKHNDIRSHSCPLIM >XP_005674861.1 PREDICTED: vitamin K-dependent protein S [Capra hircus] MRVLGGLTGTLLTCLALVLFLSRQHASQVLVRRRRANSLLEETKKGNLERECIEELCNKEEAREVFENNPETEYFYPKYLGCLGSFRAGLFTTARLSTNAYPDLRSCVNAIPDQCNPLPCNEDGYMTCKDGQATFTCICKSGWQGEKDINECKDPVNVNGGCSQICENTPGSYHCSCKNGFVMLSNKKDCKDVDECVLKPSICGTAVCKNIPGDFECECAEGYKYNPISKSCDDVDECSENLCAQLCVNYPGGYSCYCDGKKGFKLAQDQKSCEAVPVCLPLNLEKNYELLYLAEQFVGVVLYLKFRLPETTRFSAEFDFRTYDSEGVILYAESSDHSSWFLIALREGKIEIQFKNEKTVKMTTGGKVINDGLWNMVSVEELEQSISVKIAKEAVMNINKPESLFKPTNGFLETKVYFAGVPRKVENALIRPINPRLDGCIRGWNLMNQGTSGVKEIIQEKQNKHCLITVERGSYYPGTGVAQFSIDYKNESNPEAWQINVSLNIRPSAGTGVMLALVSSNTVPFALSLVDSATEKLQDILVSVESMVIARIEAESLCSDQQFLEIRVNRNNLELLTQLRDSFHSEDFQRQFAILDEAMKGTVATYLGGLPDVPFSATPVNAFYQGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVW >XP_025070223.1 vitamin K-dependent protein S isoform X1 [Alligator sinensis] MCLVSTQLLWGHGQLMPPEVLSQQHASEYLVRKRRANSFMEESKKGNLERECVEELCNKEEAREIFENDPETEYFYPKYIRCLTYTRLGISSVSVMSPDSSSDLRTCVTEISNQCTPLPCNENGYTKCIDGKAAYTCVCKQGWQGERDIDECQDQENINGGCSQTCINLHGSYRCFCEDGYYMLPNKKDCRDWDECMLRPNICGTAKCQNTPGKYECVCAEGFRYNSTTKNCEDVDECAENICAQMCVNYKGSYACHCDGHKGFKLSQDMKTCEAVPVCLPLNLEPNYQLLYLAEQTTENVLHLRFKLPNASRFSAEFDFRTYDNEGVILYAESSNNTGWFLLALRDGKIEIQFKNEHGTKVTSGGKAINDGVWQTISVEELEHSICVKIAREAVMSIKSPGNLFKQINGSLEIKVYVAGLPPKVGNTLIKQINPRVDGCARALNLMSQGHLGLTEVIKKTQIKRCLPSVGKGSYYPGTGVAKFHINYNNDTNTGEWVINVALNIRPSKGTGVMFALVSGESVPLALSIVDSSSSNSQAIIVTIGNIIIARLESKRFCTTRRLVGFSASKQQIELSVDSQDVTNSE---QELSILDQAMRGTVATYLGGLPDLPLGITPLTVFYNGCMEAKVNSKELDLDQAAYKHSDIRSHSCPQVI >XP_019331954.1 PREDICTED: vitamin K-dependent protein S [Alligator mississippiensis] MRPLAGG-----GCLLVLLFLSQQHASEYLVRKRRANSFMEESKKGNLERECVEELCNKEEAREIFENDPETEYFYPKYIRCLTYTRLGISSVSVMSPDSSSDLRTCVT----------------------------------------------------------------------------------DWDECMLRPNICGTAKCQNTPGKYECVCAEGFRYNSTTKNCEDVDECAENICAQMCVNYEGSYTCHCDGHKGFKLSQDMKTCEAVPVCLPLNLEPNYQLLYLAEQTTENVLHLRFKLPNASRFSAEFDFRTYDNEGVILYAESSNNTGWFLLALRDGKIEIQFKNEHGTKVTSGGKAINDGVWQTISVEELEHSICVKIAREAVMSIKSPGNLFKQINGSLEIKVYVAGLPPKVGNTLIKQINPRIDGCARALNLMSQGHLGLTEVIKKTQIKRCLPSVGKGSYYPGTGVAKFHINYNNDTNTGEWVINVALNIRPSKGTGVMFALVSGESVPLALSIVDSSSPNSQAIVVTVGNIIIARLESKRFCTTRRLVGFSASKQQIELTVDSQDVTNSE---QELSILDQAMRGAVATYLGGLPDLPLGITPLTVFYNGCMEAKVNSKELDLDQAAYKHSDIRSHSCPQVI >XP_015809320.1 PREDICTED: vitamin K-dependent protein S [Nothobranchius furzeri] M---KRALGRPLACLMFLVFLSQNTASQFLSRHRRANTMFEESKKGNLERECIEELCNKEEAREIFENQPETEYFYPRYVGCLGSHRVGINN-QNSDSNIPSDLRTCVKSTNNSQDPFPNPKQGSYPLIRGEPQHTKLISISYKEVRDIDECSDP-DFPAGCNQKCLNIPGSFHCMCEDGYF-LNDNIHCVDVNECLLFPSICEKAKCVNAPGMYECQCPLGFKYTSTSRTCDDVDECELGLCDDMCHNTIGSFTCHCDGRAGLRLAADERRCESIPVCVELNDYKHPEMLFLGEQFAGLVIYLRFRLPESTKFAAEFDFRTFDPEGVVLYAESSQGS-WFMLGLREGRIEVQFKNQHTSKVTSGGKAINDGQWHVISVDELKNSISVKISKEAVMSINSPESLFTSVNGKLETKFYIAGLPNRTEN-IIKPINPRLDGCIRGWNLMNQGASGVKEVIQEKKSKHCFVHVERGSFFSGAGLAHFNVDYR---DSGSWNVDLKMNIRPSSSTGVLFALVYNNTIPLSVAVLTKEEEDA-NLQVFLDGVSVATLDSLMLCYPDRTVHLNVTPTELQISANSS-VSYMTALQEALELLNRTMQNPVNTYVGGIPDIPLPLTPVSAFYHGCMDITVNDRQLDFDEALSKHNSIKSHSCPPVS >XP_020745047.1 vitamin K-dependent protein S [Odocoileus virginianus texanus] -------------------VLSRQHASQVLVRRRRANSLLEETKKGNLERECIEELCNKEEAREVFENNPETEYFYPKYLGCLGSFRAGLFTTARLSTNTYPDLRSCVNAIPDQCNPLPCNEDGYLSCKDGQATFTCICKSGWQGEKDINECKDPANVNGGCSQICENTPGSYHCSCKNGFVMLSNKKDCKDVDECVLKPSICGTAVCKNIPGDFECECAEGYKYNPVSKSCDDVDECSENLCAQLCVNYPGGYSCYCDGKKGFKLAQDQKSCEAVPVCLPLDLDKNYELLYLAEQFVGVVLYLKFRLPETTRFSAEFDFRTYDSEGVILYAESSDHSAWFLIALREGKIEIQFKNENTVKMTTGGKVINDGLWNMVSVEELEQSISVKIAKEAVMNINKPESLFKPTNGFLETKVYFAGIPRKLENALIRPINPRLDGCIRGWNLMNQGTSGVKEIIQEKQNKHCLVTVERGSYYPGTGVAQFSIDYKNESNPEAWQINASLNIRPSAGTGVMLALVSGDTVPFALSLVDSATEKLQDILVSVESTVIARIQAISLCSDQQFLEIRINRNNLELSTQLTDSFHSEDFQRQFALLDEAMKGTVATYLGGLPDVPFSATPVNAFYQGCMEVNINGVQLDLDEAISKHNDIRAHSCPSVW >XP_030271164.1 vitamin K-dependent protein S [Sparus aurata] MWIKKRALGESLACLVFLVFLSQTTAAQFLSRHKRANSLFEEHKKGNLERECIEELCNKEEAREIFENQPETEYFYPKYVVCLGSHRVGINN-QNSNSGIPSDLRTCVTEISNQCTPYPCYKEGSENCVDGQASFTCVCKPGWKGPRDINECIDP-EYPAGCDQKCHNLPGSFQCLCEDGYF-ISNKINCVDINECILFPSSCEEAKCVNTPGMYECQCPQGFKYNFTSRTCNDVDECEFNVCDGTCINTEGSYSCHCDGRQGLRLAEDKRYCEQIPVCVDLYDHKHPEMLYLGEQFAGLVIYLRFRLPENTKFAAEFDFRTFDPEGVVLYAESSQDS-WFMLGLRGGRIEVQFKNQHTFKVTSGGKAINDGQWHVISVDELESSISVKISKEAVMSINSPESLFTSVNGKLETKVYIAGLPNRTDN-VIKPINPRLDGCIRGWNLMNQGASGVKEVIQEKKSKHCFVYVERGSFFTGVGLAQFNINYS---DSGRWNVDVHMNIRPSSSTGVIFALVYNNTVPLSIAVVTQGEGEA-NLQVFLDGISVATLDSIMLCYPDRTVHLNVTPTEIQISANSS-VTYMKDLLKALERLNTTMQNPISTYVGGIPDVPLPATPVMAFYHGCMEISINDQQLDFDEALSKHNSIKSHSCPPVS >XP_040194662.1 vitamin K-dependent protein S [Rana temporaria] MMLLSSFCLILLASTLLMTFLSSQSASQFLTRKRRANSFFEESKGGDLERECIEELCNKEEAREIFENAPETEFFYPRYLACLGSHRNGNANLSYLDYDGPADLRSCVTALPDQCKPMPCHKEGYKECKDGKGNYTCVCKPGWQGVRDINECEDPEKENAGCSQRCVNFPGGYRCACEDGYYLLADKHTCNDRNECELSPVICGGAKCRNTPGKYECDCNSGYRFNTSSKTCEDVDECAEDVCSQMCVNMPGSYKCYCEGRKRFKLAGDKKSCERIPTCVPLNLETNYELLYLAEQFTGIVVYLRFKLPDVTRFSAEFDFRTYDGEGVILYAESADATSWFLLALRDGKIEIQFKNDLWTKVTTGGKSINNGDWHIVSVEELENSISVKIAKEAVMNINNPKYLFKPVNGILETKVYIAGLPRKIEN-LIKPINPRLDGCIRGWNLMNQGALGVKEFIQGKQSKHCLVDVEEGSYYPGGGLAHFKLNYTDITSEEDWIVNVTLDIRSSTGTGVMFALVKEDTVPLAIAIEDQSSDIVQDIIVSIKGITVARLSTKRICTDKNFVGITATKSALDITSDSYEIRYANEMKTQLSVLDQEMKGQLDTYLGGIPDIPPTATPVSAFYIGCMDVAINGNLIDLDEAVSKQNDIRSHSCPLIS >XP_039251316.1 vitamin K-dependent protein S-like [Styela clava] LNVMKLKIVLLLHILLGVNFIDRKEASRFLGRTKRSNSFWEEIKSGNQERECIEEDCSMEEAYEVFDNNFKANQFWKKYLRCQGKIRIARQ-ASRRSERENVKLRACISD-EDQCNPFPCVRSNTAECVDTVSSFKCVCNPGYQGELDVDECLNPSGFNSGCQQKCENFPGGYRCLCSEGYMLNFNGKTCSDINECLCRPRPCGNQICHNTKGSYTCTCDAGF--NMNGLNCEDIDECLNSPCQQVCTNSIGSYDCSCS--EGYSLNESDDTCEELFACVPQMLPEKHFLLYISQTF----------VESSSSFQIGFDFRTFDTDGMLVAVVCSDVEQHYIFLLHDGQLTVSWPPKIEITKPKNALVLSDGQWHSIILRKRKNRVTVMEGKNKLLDLKFMKNKFGSAG-----QIYYGGIPGDVTPTTIRDTDLYFQGCLKG--NYTHGFTIAGDSKMPGIHNGCFESIEKGMYFDGSGFLHQSVELQT-------NLRMRFEFKSLSAQGVIIALRSRFSVTIAIASLTTSRNET-------RSSTFTTSNGELLCDQIWICDFTITSNMVRLHVDGVNISDSK---------RVQFTGLVDLYIGGRP----GATSRSSYTGSLRNIKINRKDLSLDN-IVEMNGVRLHSIPAL-
PhyML tree of selected proteins (tr_F1QK29_F1QK29_DANRE_Vitamin_K_dependent_protein_S_OS_Danio_rerio_OX_7955_GN_pros1_PE_4_SV_1:0.31724744,(XP_030271164_1_vitamin_K_dependent_protein_S__Sparus_aurata_:0.0842438,(XP_015809320_1_PREDICTED__vitamin_K_dependent_protein_S__Nothobranchius_furzeri_:0.15685676,XP_011488632_1_vitamin_K_dependent_protein_S_isoform_X1__Oryzias_latipes_:0.17593943):0.02225137):0.10826195,(((((XP_019331954_1_PREDICTED__vitamin_K_dependent_protein_S__Alligator_mississippiensis_:0.00717383,XP_025070223_1_vitamin_K_dependent_protein_S_isoform_X1__Alligator_sinensis_:0.03213017):0.31519781,(XP_021143422_1_vitamin_K_dependent_protein_S_isoform_X1__Columba_livia_:0.05221335,(XP_416641_3_vitamin_K_dependent_protein_S__Gallus_gallus_:0.03058141,XP_019475114_1_vitamin_K_dependent_protein_S__Meleagris_gallopavo_:0.01427473):0.02612725):0.09520871):0.07292491,(((XP_023094643_1_vitamin_K_dependent_protein_S_isoform_X1__Felis_catus_:0.0876409,XP_038300575_1_vitamin_K_dependent_protein_S_isoform_X1__Canis_lupus_familiaris_:0.09884504):0.03489504,(XP_020926395_1_vitamin_K_dependent_protein_S__Sus_scrofa_:0.07414517,(NP_776863_1_vitamin_K_dependent_protein_S_precursor__Bos_taurus_:0.02497781,(((KAB0344409_1_hypothetical_protein_FD754_021335__Muntiacus_muntjak_:0.00000002,XP_020745047_1_vitamin_K_dependent_protein_S__Odocoileus_virginianus_texanus_:0.01002929):0.028163,(XP_043304830_1_vitamin_K_dependent_protein_S__Cervus_canadensis_:0.00155989,(OWK00463_1_PROS1__Cervus_elaphus_hippelaphus_:0.49137299,KAF4025963_1_hypothetical_protein_G4228_018124__Cervus_hanglu_yarkandensis_:0.00000001):0.00000001):0.00449628):0.01900108,(XP_005674861_1_PREDICTED__vitamin_K_dependent_protein_S__Capra_hircus_:0.00313784,XP_004002896_2_vitamin_K_dependent_protein_S__Ovis_aries_:0.0031068):0.01068389):0.00828778):0.05741438):0.02613947):0.0130811,((XP_024100978_1_vitamin_K_dependent_protein_S_isoform_X1__Pongo_abelii_:0.01253746,(XP_030865634_1_vitamin_K_dependent_protein_S__Gorilla_gorilla_gorilla_:0.01098277,(sp_P07225_PROS_HUMAN_Vitamin_K_dependent_protein_S_OS_Homo_sapiens_OX_9606_GN_PROS1_PE_1_SV_1:0.00155204,(XP_034812860_1_vitamin_K_dependent_protein_S_isoform_X1__Pan_paniscus_:0.00000001,XP_516603_3_vitamin_K_dependent_protein_S__Pan_troglodytes_:0.00311126):0.00155057):0.00000001):0.00000001):0.08772033,(XP_002716802_1_PREDICTED__vitamin_K_dependent_protein_S__Oryctolagus_cuniculus_:0.098894,(NP_035303_1_vitamin_K_dependent_protein_S_preproprotein__Mus_musculus_:0.04320504,NP_112348_2_vitamin_K_dependent_protein_S_precursor__Rattus_norvegicus_:0.03348535):0.13082858):0.01745568):0.01051911):0.282238):0.06535383,(XP_040194662_1_vitamin_K_dependent_protein_S__Rana_temporaria_:0.19116117,XP_018104341_1_vitamin_K_dependent_protein_S_isoform_X2__Xenopus_laevis_:0.18240942):0.20749213):0.01234312,XP_039251316_1_vitamin_K_dependent_protein_S_like__Styela_clava_:2.60242629):0.4563255);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)