PB0116

DATABASE

Click here to access PB0116 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0116	P04004	Vitronectin	VTN	V75, VN, VNT	Homo_sapiens	Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.

Domains

Gene Ontology

PF00045 (4_Hemopexin) PF01033 (Somatomedin_B)

GO:0005044 (enables) scavenger receptor activity GO:0005178 (enables) integrin binding GO:0005201 (enables) extracellular matrix structural constituent GO:0005515 (enables) protein binding GO:0008201 (enables) heparin binding GO:0030247 (enables) polysaccharide binding GO:0050840 (enables) extracellular matrix binding GO:0006897 (involved in) endocytosis GO:0006955 (involved in) immune response GO:0007155 (involved in) cell adhesion GO:0007160 (involved in) cell-matrix adhesion GO:0010951 (involved in) negative regulation of endopeptidase activity GO:0014911 (involved in) positive regulation of smooth muscle cell migration GO:0016477 (involved in) cell migration GO:0030155 (involved in) regulation of cell adhesion GO:0030195 (involved in) negative regulation of blood coagulation GO:0030949 (involved in) positive regulation of vascular endothelial growth factor receptor signaling pathway GO:0032092 (involved in) positive regulation of protein binding GO:0033627 (involved in) cell adhesion mediated by integrin GO:0035987 (involved in) endodermal cell differentiation GO:0048260 (involved in) positive regulation of receptor-mediated endocytosis GO:0050731 (involved in) positive regulation of peptidyl-tyrosine phosphorylation GO:0051918 (involved in) negative regulation of fibrinolysis GO:0061302 (involved in) smooth muscle cell-matrix adhesion GO:0090303 (involved in) positive regulation of wound healing GO:0005576 (located in) extracellular region GO:0005615 (located in) extracellular space GO:0005783 (located in) endoplasmic reticulum GO:0043231 (located in) intracellular membrane-bounded organelle GO:0062023 (located in) collagen-containing extracellular matrix GO:0070062 (located in) extracellular exosome GO:0072562 (located in) blood microparticle GO:0098637 (located in) protein complex involved in cell-matrix adhesion GO:1904090 (located in) peptidase inhibitor complex GO:0071062 (part of) alphav-beta3 integrin-vitronectin complex

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|P04004|VTNC_HUMAN Vitronectin OS=Homo sapiens OX=9606 GN=VTN PE=1 SV=1 MAPLRPLLILALLAWVALADQESCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAECKP QVTRGDVFTMPEDEYTVYDDGEEKNNATVHEQVGGPSLTSDLQAQSKGNPEQTPVLKPEE EAPAPEVGASKPEGIDSRPETLHPGRPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYC YELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYP RNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQEECEGSSLSA VFEHFAMMQRDSWEDIFELLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMA PRPSLAKKQRFRHRNRKGYRSQRGHSRGRNQNSRRPSRATWLSLFSSEESNLGANNYDDY RMDWLVPATCEPIQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPAPGHL
Selected proteins from model organisms >sp|P04004|VTNC_HUMAN Vitronectin OS=Homo sapiens OX=9606 GN=VTN PE=1 SV=1 MAPLRPLLILALLAWVALADQESCKGRCTEGFNVDKKCQCDELCSYYQSCCTDYTAECKP QVTRGDVFTMPEDEYTVYDDGEEKNNATVHEQVGGPSLTSDLQAQSKGNPEQTPVLKPEE EAPAPEVGASKPEGIDSRPETLHPGRPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYC YELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYP RNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQEECEGSSLSA VFEHFAMMQRDSWEDIFELLFWGRTSAGTRQPQFISRDWHGVPGQVDAAMAGRIYISGMA PRPSLAKKQRFRHRNRKGYRSQRGHSRGRNQNSRRPSRATWLSLFSSEESNLGANNYDDY RMDWLVPATCEPIQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPAPGHL >NP_035837.1 vitronectin precursor [Mus musculus] MAPLRPFFILALVAWVSLADQESCKGRCTQGFMASKKCQCDELCTYYQSCCADYMEQCKPQVTRGDVFTM PEDDYWSYDYVEEPKNNTNTGVQPENTSPPGDLNPRTDGTLKPTAFLDPEEQPSTPAPKVEQQEEILRPD TTDQGTPEFPEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDETAVRPGYPKLIQDVWGIEGPIDAAFT RINCQGKTYLFKGSQYWRFEDGVLDPGYPRNISEGFSGIPDNVDAAFALPAHRYSGRERVYFFKGKQYWE YEFQQQPSQEECEGSSLSAVFEHFALLQRDSWENIFELLFWGRSSDGAREPQFISRNWHGVPGKVDAAMA GRIYVTGSLSHSAQAKKQKSKRRSRKRYRSRRGRGHRRSQSSNSRRSSRSIWFSLFSSEESGLGTYNNYD YDMDWLVPATCEPIQSVYFFSGDKYYRVNLRTRRVDSVNPPYPRSIAQYWLGCPTSEK >XP_043335857.1 vitronectin [Cervus canadensis] MTSLRPLLMLALLAWAVVADQESCKGRCAEGFNATRKCQCDELCSYYQSCCADFMAECKPQVTRGDVFHLPEDEYRFYDY NEAQTVNLSTEAQPESPNLAPVLQAQTQETPVEAPVLSPEKEAPLPGRGDSEPEVGTSDPGISESPAEEETCSGKPFDAF TDLKNGSLFAFRGLYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRVNCEGKTYLFKGSLYWRFEDGVLEPDFPRNIS DGFKGIPDDVDAALALPAHSYNGRERVYFFKGNHYWEYVFQQQPSQEECEGGSQPAAFKHFALMQRDSWEDIFRLLFWGG PSGGAGQPRLISRDWLGLPRRLDAAMAGHIYVSGSAPSFPQAKMTKSARRHRKRYRSLRNRGRGRGRGRSRSQNPYRRSR STWLSWFSSEELGLGANNYDNYEMDWLVPATCEPIQSVYFFSEDKYYRVNLRTRRVDTVIPPYPRSIAQYWLGCPVPGHA >KAF4012137.1 hypothetical protein G4228_003124 [Cervus hanglu yarkandensis] MTSLRPLLMLALLAWAVVADQESCKGRCAEGFNATRKCQCDELCSYYQSCCADFMAECKPQVTRGDVFHLPEDEYRFYDY NEAQTVNLSTEAQPESPNLAPVLQAQTQETPVEAPVLSPEKEAPLPGRGDSEPEVGTSDPGISESPAEEETCSGKPFDAF TDLKNGSLFAFRGLYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRVNCEGKTYLFKGSLYWRFEDGVLEADFPRNIS DGFKGIPDDVDAALALPAHNYNGRERVYFFKGNHYWEYVFQQQPSQEECEGGSQPAAFKHFALMQRDSWEDIFRLLFWGG PSGGAGQPRLISRDWLGLPRRLDAAMAGHIYVSGSAPSFPQAKMTKSARRHRKRYRSLRNRGRGRGRGRSRSQNPYRRSR STWLSWFSSEELGLGANNYDNYEMDWLVPATCEPIQSVYFFSEDKYYRVNLRTRRVDTVIPPYPRSIAQYWLGCPVPGHA >OWK14767.1 VTN [Cervus elaphus hippelaphus] MTSLRPLLMLALLAWAVVADQESCKGRCAEGFNATRKCQCDELCSYYQSCCADFMAECKPQVTRGDVFHLPEDEYRFYDY NEVQTVNLSTEAQPESPNLAPVLQAQTQETPVEAPVLSPEKEAPLPGRGDSEPEVGTSDPGISESPAEEETCSGKPFDAF TDLKNGSLFAFRGLYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRVNCEGKTYLFKGSLYWRFEDGVLEPDFPRNIS DGFKGIPDDVDAALALPAHNYNSRERVYFFKGNHYWEYVFQQQPSQEECEGGSQPAAFKHFALMQRDSWEDIFRLLFWGG PSGGAGQPRLISRDWLGLPRRLDAAMAGHIYVSGSAPSFPQAKMTKSARRHRKRYRSLRNRGRGRGRGRSRSQNPYRRSR STWLSWFSSEELGLGANNYDNYEMDWLVPATCEPIQSVYFFSEDKYYRVNLRTRRVDTVIPPYPRSIAQYWLGCPVPGHA >KAB0358735.1 hypothetical protein FD754_002891 [Muntiacus muntjak] MTSLRPLLMLALLAWAVVADQESCKGRCAEGFNATRKCQCDELCSYYQSCCADFMAECKPQVTRGDVFHLPEDEYRFYDY NEAQTVNLSVETQPESPTLAPVLQAQTQETPVQAPVLSPEKEAPLPGRGDSEPEVGTTDPAEEETCSGKPFDAFTDLKNG SLFAFRGLYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRVNCQGKTYLFKGSLYWRFEDGVLEPDFPRNISDGFKGI PDDVNAALALPAHNYNGRERVYFFKGNHYWEYVFQQQPSQEECEGGSQPAAFKHFALMQRDSWEDIFRLLFWGGPSGGAG QPRLISRDWLGLPRRLDAAMAGHIYVSGSAPSFPQAKMTKSARRHRKRYRSLRSRGRGRGRSRSQNPYRRSRSTWLSWFS SEELGLGANNYDNYEMDWLVPATCEPIQSVYFFSEDKYYRVNLRTRRVDTVIPPYPRSIAQYWLGCPVPGHA >KAB0367524.1 hypothetical protein FD755_020848 [Muntiacus reevesi] MTSLRPLLMLALLAWAVVADQESCKGRCAEGFNATRKCQCDELCSYYQSCCADFMAECKPQVTRGDVFHLPEDEYRFYDY NEAQTVNPSVETQPESPTLAPVLQAQTQETPVQAPVLSPEKEAPLPGRGDSEPEVETSDPAEEETCSGKPFDAFTDLKNG SLFAFRGLYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRVNCQGKTYLFKGSLYWRFEDGVLEPDFPRNISDGFKGI PDDVDAALALPAHNYNGRERVYFFKGNHYWEYVFQQQPSQEECEGGSQPAAFKHFALMQRDSWEDIFRLLFWGGPSGGAG QPRLISRDWLGLPRRLDAAMAGHIYVSGSAPSFPQAKMTKSARRHRKRYRSLRSRGRGRGRSRSQNPYRRSRSTWLSWFS SEELGLGANNYDNYEMDWLVPATCEPIQSVYFFSEDKYYRVNLRTRRVDTVIPPYPRSIAQYWLGCPVPGQA >NP_001184010.1 vitronectin L homeolog precursor [Xenopus laevis] MKVLLFPALLLLLGAVRAAHAAEESCAGRCFSGFDGNKKCQCDIICVHFESCCIDYLTLCKPKEQRGDVFEIPEDEYNYD SGTSEPELASKVNEELEETPDDTTEPVENLPPKIEEVIQPDQMEESQDELCSGQPFDAFTNIKNGSIYAFRGKYFYELDD KSALEGYPKLIKDVWGIDGPVDAAFTRMNCQGKTYLFKGKEYWRFSNGVLESDYPRNISEGFHDIPDNIDAAFALPANNH NDREKVYFFKGNKYWQYEFQNQPSRKDCQDSAQSELFTYYVTLQKDSWEDFFSFLFGPSMKRSTAGPWYINKDWKGVPNN VDAVLPSRIYVPKQTRRSRRRKSRRRNNRKKSGGMRSLWSDFSFDPLDGLFDYDDEQSDPDWLPPERPADCQPTQNVYFF KNDKYYRVNLRTKRVDYVYPPYPRSIAQYWLGCKKDERLEKSRG >XP_015807112.1 PREDICTED: vitronectin-like [Nothobranchius furzeri] MRLFIILLLALVADGLTEDESCLVRCENGFDSERKCQCDSMCKYYSSCCKDYEALCGMMTRGDTFEFAEDDYDLSVITAT SDQHSTGSQSPTAPSTPQPLVPDFSHRLRQSPEISLQMTRPPHLKNHRVTPVSPPPKSEPSTVTSSPQTHTTAQTTTVPT TKATTAAPDPDAEVCSGRPFDAFMQLKNGSIYAFRGKYFFELDQKSVLTGYPKLIKDVWGIEGPIDAAFTRINCQGKTYI FKGNKYWRFDNNELDDDYPRDISVGFDKIPDHVDAAFALPAHSHHGKEKVYFFKNDQYYVYEFLHQPSHEECAVMSERSP SALFRRYTDLYYNNYERFFHELFSDLPQHHDKHHFINKDWKGLKSPVDAAMSGRIYITTGRSMPRRYDYQPDQQGGGRQW GQQNGWQRGQRRWNRSPHWGSAAEQGLNMGQRFAERGMEMGMRLAERRMEMEDRLGRDWDRRWDQDWDQDRRWDRYNQNN RGNYDSRNDRSFLRDMPIQSVYFFKADKYYRVDLRTKRVDPAMPPYPRSIAKYWLGCSDTTGAEKK >XP_021337086.1 vitronectin isoform X1 [Danio rerio] MRVFLLLLVLLSFADAAEESCIERCENGFDATKSCQCDSMCTYYKSCCTDYESLCRIKARGDTFPSHPEDDYDEETNSTE VPIRSRPQVRVLSPSPLEISSMVTPVLDTANEPTPVVATAATPTNKNPATTPGATTTAQPTPTKAKDPDAEVCSGRPFDA FMQLKNGSIYAFRGEYFFELDEKSVLPGYPKLIEDIWGIKGPIDAAFTRINCQGKTYIFKGNKYWRFDDGVLDDDFPRDI AVGFEKIPDHLDAAFATPAHSHHGKEKVYFFKGDQYYHYEFKHQPSHEECIKMSLRSPSMLFRRYTDIYYDRWTEHFNQL FGGAQSHHGHHFINRDWIGIKSPVDAVLVGRLYVTPRWQNRRRQDRNRQDWDQQQGQQYGQQWDQRYGQQWGSRRRQNRS PYWESMAERGISIGQEFSQRFGQDRWRDQDRRRDYYYDRQNDYDYDYRYKPTEDIVYNILRRSQPLQSVYFFKGDKYYRV NLQTKRVDYANPPYPRPIGKYWLGCKDTSGAEKR >XP_030260427.1 vitronectin-like [Sparus aurata] MRLWAILLLALLAQALAEDKSCMGRCENGFNSERKCQCDSMCKYYKSCCSDYEVTCGMTTRGDTYVSADDDDELFEGTTP SPFTPSPFTPSPSTATSRQLRPKQQAISDFGRRGQQRHETTLEMTRPPRLMDTIIQRIPVIQRTPISEAVTPTQDVASTT KAPQTTVPSTTGTTAAPDPDAVVCSGRPFDSFMQLKNGSIYAFRGDYFFELDQKSVLPGYPKLIKDVWGIRGPIDAAFTR VNCQGKTYIFKGNQYWRFDNGVLDDDYPRDISVGFDKIPDHVDAAFALPAPGHNGKEKVYFFKGEQYYTYEFLHQPSHEE CITMSESSPSTLFRRYTDIYYNNYERSLSELFSDLPQHHDKHHFIEKDWKGLKAPLDAVMTGRMYVPPLRSTPRRNDYRY DQQYGQQYGQQYGQQWDQQWGRRRQSRSPNWGSMAERGMNMGQGFAERGMEMGLRLAEKRMEMEERLGRDWDRRWDQDWD QDRRRDGHRQNNRGNYDSRSYLEPIRREQPIQTVYFFKGDKYYRVDLRTKRVDPGSPPYPRSIAKYWLGCSDTAGAEK >XP_023818375.1 vitronectin [Oryzias latipes] MKPALALLSLLLVVESTSAAEESCVGLCGSFDPERKCQCDSMCVYYSSCCGDFSNICAKKVTRGDVFGSVENTTAIVTPN VSSAAPTVQSSSAPQPTSTFGPTAHTDPDAAPCSGRPFDAFLQLKNGSIYAFRGDYFFELDDDSILPGYPKLIQDAWGIS GPISAAFTRINCQGKSYIFKGSRYWRYNGNVLDEGFPRDISEGFQDIPNDIDAAFTVPAPNHRGKEKAYFFKGDKYYKYE FKHQPSHEECVQMTKASPSVLFTQYTDLFCDQTAEDLFTGLFGSSFDSQRTNPRFISGDWHGIRPPVDAAVVGRVHLSVK PTASPPRRGSSRRRGSSRRRGPHRRRLSHRWFGDLWNDDDFAFSMDESDFTDQSTTTDNRQIPVQNVYFFKKDKYYRVGL RSKRVDFANPPYPRSIAKYWLGCKEEEMPDSSRAEKK >NP_062029.2 vitronectin precursor [Rattus norvegicus] MASLRPFFILALLALVSLADQESCKGRCTQGFMASKKCQCDELCTYYQSCCVDYMEQCKPQVTRGDVFTM PEDEYWSYDYPEETKNSTSTGVQSENTSLHFNLKPRAEETIKPTTPDPQEQSNTQEPEVGQQGVAPRPDT TDEGTSEFPEEELCSGKPFDAFTDLKNGSLFAFRGEYCYELDETAVRPGYPKLIQDVWGIEGPIDAAFTR INCQGKTYLFKGSQYWRFEDGVLDPDYPRNISEGFSGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEY EFQQQPSQEECEGSSLSAVFEHFALLQRDSWENIFELLFWGRSSDGAKGPQFISRDWHGVPGKVDAAMAG RIYITGSTFRSVQAKKQKSGRRSRKRYRSRRGRGHSRSRSRSMSSRRPSRSVWFSLLSSEESGLGTYNYD YDMNWRIPATCEPIQSVYFFSGDKYYRVNLRTRRVDSVNPPYPRSIAQYWLGCPTSEK >NP_990392.1 vitronectin precursor [Gallus gallus] MRLLLPVLVLALLALTRAAEDSCEGRCDEGFNAMKKCQCDTLCNYYQSCCSDYSTVCKAKVTRGDVFALP EDDYLDYDLSIDTGTVGPTEAPAPTEHPTEPHSSPSPTRVIDTATEETPEEPEVPTLHPTTTTTTTTSDE TRNPSLDDEPEELCSRKPFNAFTDLKNGSIYAFRGKYFYELDKSSVRPGYPKLISDVWGIEGPIDAAFTR INCQGKTYLFKGSQYWRFDDGALDPGYPRDISEGFEGIPNDIDAAFALPAHSYHGNERVYFFKGKYYWSY DFAHQPTQAECEKSSPSTVFNHYAFMNRDSWEDIFLSLFGSRMVGASSQRLISRDWRGVPNQLDAAMAGR IYVSSRQPRRRSSRRHRKRYRNHRTLNLGLWSWLNSDSESTDTESDWLSGSQCETLQSVYFFVGDKYYRV NLRTKRVDLVQPPYPRSIAQYWLDCPQPDEEST >NP_999269.1 vitronectin precursor [Sus scrofa] MAPLRPLLMLALLAWVALADQESCKGRCTDGFIAERKCQCDELCSYYQSCCTDYVAECKPQVTRGDVFLQ PDDEYRAYDYHEETRHNTSVQEEQRIPVLLAKTEETPVLKPEEEAPPPGPQTDDLGVPEEELCSGKPFDA FTNLKNGSVFAFRGLYCYELDEKAVRPGYPKLIQDVWGIKGPIDAAFTRINCQGKTYLFKGSQYWRFDDG VLDPNYPREISEGFKGIPDDVDAALALPAHSYSGRERVYFFKGKQYWEYVFQQQPSREECEGSSPSDVFA HFALMQRDSWEDIFRLLFWSHSFGGAIEPRVISQDWLGLPEQVDAAMAGQIYISGSALKPSQPKMTKSAR RSGKRYRSRRGRGRGRGHSRSQKSHRQSRSTWLPWFSSEETGPGGYNYDDYKMDWLVPATCEPIQSVYFF SGEEYYRVNLRTQRVDTVTPPYPRSIAQYWLGCPVPDQK >XP_854040.1 vitronectin [Canis lupus familiaris] MAFPRPLLVLALLAWVVLADQESCKGRCTEGFNADRKCQCDELCSYYQSCCEDYVAECKPQVTRGDVFAL PEDEYGVIDDHEGTREQSVLTQLESTTLSPGLQAQSEKFPAQVPILIPEEEAPGPGQGTLVLEAPDQDIS ESAAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQG KTYLFKGSQYWRFEDGVLDPDYPRNISEGFKGIPDNVDAAFALPARSYSGRERVYFFKGRQYWEYEFQQQ PSQEECEGSSLSTVFEHFALLQRDSWETFFELLFWNRPSGGAGEPGFISQDWPGLPRQVDAAMAGRIYIS GSAPRSWVKKLNPKRRNRKRYRSRRNRGRGRSRTSQRQSRSAWLSWFSSEESGLDTYNYDDYNMDWLVPA TCEPIQSVYFFSEDKYYRVNLRTRRVDTVSPPYPRSIAQYWLGCSAPSPQ >NP_001030222.1 vitronectin precursor [Bos taurus] MTSLRPLLMLALLAWVVVADQESCKGRCTEGFNATRKCQCDELCSYYQSCCADFMAECKPQVTRGDVFHL PEDEYGFHDYSDAQTVNSNVEAQPESTTLAPVLQAQTLETPVQAPVLNPEKEVPPSGRGDSEPGMGTSDL GTSESPAEEETCSGKPFDAFTDLKNGSLFAFRGLYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRVN CQGKTYLFKGSQYWRFQDGVLEPDFPRNISDGFGGIPDDVDAALALPAHNFNGRERVYFFKGNHYWEYVF QQQPSQEDCEGSSLPAAFKHFALMQRDSWVDIFRLLFWGGSYGGAGQPQLISRNWFGLPGRLDAAMAGHI YVSGSAPSFPRAKMTKSARRHRKRYRSLRSRGRGRGRNQNPYRRSRSAFLSWLSSEELGLGANNYDSFEM DWLVPATCEPIQSVYFFSEDKYYRVNLRTRRVDAVIPPYPRSIAQYWLGCPVPGQA >XP_001146856.1 vitronectin [Pan troglodytes] MAPLRPLLILALLAWVALADQESCKGRCTEGFNADKKCQCDELCSYYQSCCTDYTAECKPQVTRGDVFTM PEDEYTVYDDGEEKNNATVHEQVGGPSLTSDLQAQSEGNPEQTPVLKPEEEAPAPEVGASKPEGIDSRPE TLHPGRPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAF TRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYW EYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFELLFWGRTSAGTRQPQFISRDWHGVPGQVDAAM AGRIYISGMAPRPSLAKKQKFRHRNRKGYRSQRGHSRGRNQNSRRPSRATWLSLFSSEESNLGANNYDDY RMDWLVPATCEPIQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPAPGHL >NP_001075761.1 vitronectin precursor [Oryctolagus cuniculus] MAPLRPIFTLALLLWVVLADQESCKDRCTEGFNANRKCQCDELCSYYQSCCADYAAECKPQVTRGDVFTM PEDEYGPYDYIEQTKDNASVHAQPESPTVGQEPTLSPDLQTEGGAEPTHEVPLEPEMETLRPEGEDLQAG TTELGTSASPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDETAVRPGYPKLIQDVWGIEGPIDAAF TRINCQGKTYLFKGSQYWRFEDGILDPDYPRNISEGFSGIPDNVDAAFALPAHSYSGRERVYFFKGDKYW EYQFQQQPSQEECEGSSLSAVFEHFAMLHRDSWEDIFKLLFWGRPSGGARQPQFISRDWHGVPGKVDAAM AGRIYISGLTPSPSAKKQKSRRRSRKRYRSRYGRGRSQNSRRLSRSISRLWFSSEEVSLGPYNYEDYETS WLKPATSEPIQSVYFFSGDKYYRVNLRTQRVDTVNPPYPRSIAQYWLGCPAPGGQ >NP_001127063.1 vitronectin precursor [Pongo abelii] MAPLRPLLILALLAWVALADQESCKGRCTEGFNADKKCQCDELCSYYQSCCTDYTAECKPQVTRGDVFTM PEDEYSVYDDGEEKNNATVHEQLGGPSLTPDFQAQPEGNPEQAPVLKPEEEAPAPEVGTSRPEGMDSRPE TLHPGRPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAF TRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYW EYQFQHQPSQEECEGSSLSAVFEHFAMIQRDSWEDIFELLFWGRTSAGTRQPQFISRDWHGVPGQVDAAM AGRIYISGMAPRPALAKKQKFRRRNRKGYRSHRGHSRGRNQNSRRPSHAMWLSLFSSEDSNLGANNYDDY RMDWLVPATCEPIQSVFFFSGDKYYRVNLRTRRVDAVDPPYPRSIAQYWLGCPAPGHL >XP_003211803.2 vitronectin [Meleagris gallopavo] MRLLLLVLVLALLAPTRAAEDSCEGRCDEGFNALKKCQCDNLCNYYQSCCSDYSTVCKAKVTRGDVFALP EDDYLDYDLPIDTGTEGPTGAPAPTEHPTEPHTFPLPTRETDTATEETPVETEVPTLHPTTTTTTTTSEG TRNPSLEDEPEKLCSRKPFNAFTDLKNGSLYAFRGKYFYELDESSVRPGYPKLISDVWGIEGPIDAAFTR INCQGKTYLFKGNKYWRFDDGALEPGYPRDISEGFEGIPNDIDAAFALPAHSYHGNERVYFFKGKYYWSY DFAHQPTQAECDKSSPSTVFNHYAFMNRDSWEDIFFSLFGSRMVGASSPRLISRDWRGVPNQLDAAMAGR IYVSSRQPRRRNSRRHRKRYRNHRTLNLGFWGWLNNDSESTDTESDWLSGSQCETLQSVYFFVGDKYYRV NLRTKRVDLVQPRYPRSIAQYWLDCPQPDEEST >XP_005693309.1 PREDICTED: vitronectin [Capra hircus] MTSLRPLLMLALLVWVVVADQESCKGRCTEGFNATRKCQCDELCSYYQSCCADFMAECKPQVTRGDVFHL PEDEYGTYDYGEVQTVNRSVEAQPESPTLAPVLQAEIPVQAPVLNPEKEAPSPGRGDSDPGLGTSDLGTS ESPAEEETCSGKPFDAFTDLKNGSLFAFRGLYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRFNCQG KTYLFKGSQYWRFEDGVLEPDFPRNISDGFKGIPDDVDAALALPAHSYNGRERVYFFKGNHYWEYVFQQQ PSREECEGSSQPAAFKHFALMQRDSWEDIFRLLFWGGSFGGAGQPQLISRDWFGLPGKLDAAMAGHIYIS GSAPSSPRAKMTKSARRHRKRYRSLRSRGRGRGRARSQNPYRRFRSTWLSWFSSEELGLGADNYDNYEMD WLVPATCEPIQSVYFFSEDKYYRVNLRTRRVDSVIPPYPRSIAQYWLGCPVPGHA >XP_003812709.1 vitronectin [Pan paniscus] MAPLRPLLILALLAWVALADQDSCKGRCTEGFNADKKCQCDELCSYYQSCCTDYTAECKPQVTRGDVFTM PEDEYTVYDDGEEKNNATVHEQVGGPSLTSDLQAQSEGNPEQTPVLKPEEEAPAPEVGASKPEGIDSRPE TLHPGRPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAF TRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYW EYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFELLFWGRTSAGTRQPQFISRDWHGVPGQVDAAM AGRIYISGMAPRPSLAKKQKFRHRNRKGYRSQRGHSRGRNQNSRRPSRATWLSLFSSEESNLGANNYDDY RMDWLVPATCEPIQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPAPGHL >XP_003996546.1 vitronectin [Felis catus] MASPRPLLILALLAWVVLADRESCKGRCTEGFNADRKCQCDELCSYYQSCCEDYVAECKPQVTRGDVFTL PEDEYGVYNYFEETRDNSSVLPQPESTSQGPDLQAQTEVSPDQETFEEPLLNPTQETLGPETSDQDIPES PVVEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEEAVSPGYPKLIQDVWGIEGPIDAAFTRINCQGKT YLFQGHQYWRFEDGVLDPDYPRNISEGFKGIPDNVDAALALPAHSYSGRERAYFFKGRQYWEYEFQQQPS QEECEGSSLSAVFEHFALLQRDSWETLFEFLFGNRFSGGAGQPRLISRDWPGVPRQVDAAMAGRIYISGS APQSWAEKQKSRRRNRKRYRSRRNRGRGRSQNPHRQSRSAWLSWLSSEEDSLGIYNFRDYDMDWLVPATC EPIQSVYFFSGDKYYRVNLRTRQVDTVSPPYPRSIAQYWLGCPAPGHQ >XP_027831040.1 vitronectin [Ovis aries] MTSLRPLLMLALLAWVVVADQESCKGRCTEGFNATRKCQCDELCSYYQSCCADFMAECKPQVTRGDVFHL PEDEYGTYDYGEVQTVNRSVEAQPESPTLAPVLQAEIPVQAPVLNPEKEAPSPGRGDSDPGLGTSDLGTS ESPAEEETCSGKPFDAFTDLKNGSLFAFRGLYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRFNCQG KTYLFKGSQYWRFEDGVLEPEFPRNISDGFKGIPDDVDAALALPAHSYNGRERVYFFKGNHYWEYVFQQQ PSQEECEGSSQPAAFKHFALMQRDSWEDIFRLLFWGGSFGGAGQPQLISRDWFGLPGKLDAAMAGHIYIS GSAPSSPRAKMTKSARRHRKRYRSLRSRGRGRGRGRSQNPYRRFRSTWLSWFSSEELGLGADNYDNYEMD WLVPATCEPIQSVYFFSEDKYYRVNLRTRRVDSVIPPYPRSIAQYWLGCPVPGHA >XP_004042098.1 vitronectin [Gorilla gorilla gorilla] MAPLRPLLILALLAWVALADQESCKGRCTEGFNADKKCQCDELCSYYQSCCTDYTAECKPQVTRGDVFTM PEDEYTVYDDGEEKNNATVHEQLGGPSLTSDLQAQSEQNPEQTPVLKPEEEAPAPEVGSSKPEGVDSRPE TLHPGRPQPPAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAF TRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYW EYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFELLFWGRTSAGTRQPQFISRDWHGVPGQVDAAM AGHIYISGMAPRPSLAKKQKFRHRNRKGYRSQRGHSRGRNQNSRRPSRATWLSLFSSEESNLGANNYDDY RMDWLVPATCEPVQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPAPGHL >XP_013222293.1 vitronectin [Columba livia] MKLLFAVLALALLAAARAAEDSCEGHCDDGFDARRKCQCDTLCVYYQSCCSDYSTACKAKVTRGDVFALP EDDYLDYNLTVDLGTEPSTKAAPTELPTTPLPVQPTPESEPGPEETLTETPMEEVPSTTADGLGERDPEE EPEELCSGKPFNAFTDLKNGSLYAFRGKYFYELDETSVRPGYPKLISDVWGIEGPIDAAFTRINCQGKTY LFKGSQYWRFDDGALDPGYPRNISDGFEGIPNSIDAAFALPAHSYHGNERVYFFKDKYYWSYDFAQQPTQ ADCEKSSPSTVFNHYAFMNRDSWEDVFHILFGGRITGASSPRYISRDWQGVPGRQDLRGHPPAPQEEVSP PAQEVQEPPVTEFGFLGLAGK >XP_025070384.1 vitronectin [Alligator sinensis] MGLLLPAVLLGLFGVALAAEESCAGRCDVAFNSSMKCQCDPLCVYYQSCCSDYNSVCKTKVTRGDVFAFP EDDYSYFYGNKGDPFDQGTGSPDVATTFPAPSTSEMWTEEPTQQWELSTDPSVTTEALPATVEDWNQDEE QEEACSGKTFDAFTDLKNGSIFAFRGKYFYELNETSVMPGYPKLIRDVWGMDGPIDAAFTRINCQGKTYI FKGSQYWRFDDGALDPGYPLNISEGFEGIPDDLDAAFALPAENYADNERVYFFKGRHYWSYEFAQQPTWE ECEEQDSQSAAFWHFAFLVGTDWDDIFDMPFGLSSSKCRGAWGGEAWECELSPSRRFWPWLQDDSESWEL DSDWVYMGTRCQPVQSIYFFVGDKYYRVNLKTMRVDWVHPRYPRPVAQYWLGCPRLEPKRP >XP_020740434.1 vitronectin isoform X1 [Odocoileus virginianus texanus] MISRRPLLMLALLAWAAVADQESCKGRCAEGFNATRKCQCDELCSYYQSCCADFMAECKPQVTRGDVFHL PEDEYRFYDYNEEQTVNLSVEAQPESPTLAPVLQAQTQETPVQAPVLSPEKEAPLLGRGDSEPEVETSDP EISESPAEEETCSGKPFDAFTDLKNGSLFAFRGLYCYELDEKAVRPGYPKLIQDVWGIEGPIDAAFTRVN CQGKTYLFKGSLYWRFEDGVLEPDFPRNIADGFKGIPDDVDAALALPAHSYNGRERVYFFKGNHYWEYVF QQQPSQEECEGSSQPAAFKHFALMQRDSWEDIFRLLFWGGPSGGAGQPRLISRDWLGLPRRLDAAMAGHI YVSGSAPSFPQAKMTKSARRHRKRYRSLRSRGRGRGRSRSQNPYRRSRSTWLSWFSSEELGLGANNYDNY EMDWLVPATCEPIQSVYFFSEDKYYRVNLRTRRVDTVIPPYPRSIAQYWLGCPVPGHA >XP_040194287.1 vitronectin [Rana temporaria] MRALLLPAILLLGAIDSALPAEESCVGRCLEGFNAKIKCQCDDLCIYYGSCCSDFNVVCVKKETRGDVFT FPEDEFDNFNDTTDPNPLTQETTPVDKPGEAETVTERPTKGTTTVDPVTDDIPEELCSGKPFDAFTNLKN GSIYAFRGEYFYELDDKKALDGYPKRIKDVWGIEGPIDAAITRMNCEGKTYIFKGTQYWRFSDGVLDSDY PRDIDVGFKNIPNDIDAAFALPANNYQGKERAYFFKGRQYWQYEFTQQPTREECLGSPPSEIFTRYAAMQ DDSWEDIFSLLFGKLFTGNSAEPKSISRDWRGVPYGVNAVLPSRIYIPQQKQPALRRSKRRKSSRRKNRR RRPSKPSYYDFSDLYDFDDYEDDPDWLPPESQPTCQPVQSVFFFKDDKYYRVNLQTKRVDYTYPPYPRSI AEYWLGCKKTSKQKKSRS >NP_001189002.1 matrix metalloproteinase 1, isoform H [Drosophila melanogaster] MTNCQSSVFIVVGTLFSIMAAAQSAPVSTTTQAEIYLSQFGYLPASARNPASSGLHDQRTWVSAIEEFQSFAGLNITGEL DAETMKLMSLPRCGVRDRVGTGDSRSKRYALQGSRWRVKNLTYKISKYPKRLKRVDVDAEIGRAFAVWSEDTDLTFTRKT SGPVHIEIKFVESEHGDGDAFDGQGGTLAHAFFPVFGGDAHFDDAELWTIGSPRGTNLFQVAAHEFGHSLGLSHSDQSSA LMAPFYRGFEPVFKLDEDDKAAIQSLYGRKTNQLRPTNVYPATTQRPYSPPKVPLDDSICKDSKVDTLFNSAQGETYAFK GDKYYKLTTDSVEEGYPQLISKGWPGLPGNIDAAFTYKNGKTYFFKGTQYWRYQGRQMDGVYPKEISEGFTGIPDHLDAA MVWGGNGKIYFFKGSKFWRFDPAKRPPVKASYPKPISNWEGVPNNLDAALKYTNGYTYFFKGDKYYRFHDARFAVDSATP PFPRPTAHWWFGCKNTPSSTAVGDHQSNDEPIVPEVAERTGNGAMSQSKLTSSSAVSTVITTILMCLVSKLIVS >KAG6797835.1 Matrix metalloproteinase-14 [Apis mellifera caucasica] MTLPRCGVKDKVGPGFGRSKRYALQGSRWRVKKLSYKISKYPRNLPQHKVDAELNKAFKVWSEYTDLVFVQKKSGQVHIE IRFEKGEHGDGDPFDGPGGTLAHAYFPVYGGDAHFDDAEQWTIDSFRGTNLFQVAAHEFGHSLGLSHSDVKSALMAPFYR GYEPYFRLDEDDIQGIQALYGTKTSNNGGVPSGPKPTTTASPSEEDSELCTNSKVDTMFNSAEGHMYVFKGDRYWRLTSD GVAIGYPKLISHSWKGLPGNIDAAFTYKNGKTYFFKGSKYWRYVGKKMDGDYPKEISEGFTGIPDNIDTVTVWTGNGKLY FYKGSKFWRFDPSQKPPVKNTYPKLISNWEGLPDNLDASIVYRGYTYFFKGDAYYRFNDRTFSVDIADPAFPRSTAYWWF GCRSANKGTLGNGSMNRWYNSQCNGNECLWFPENAINTFLNGGDFFIPDSVDGDNNDVGDIILDAGIKASFESDQILTSP >XP_039256216.1 matrix metalloproteinase-24-like [Styela clava] MKKGLYVVLTFVLLCATGAHPAPTQSKGVDFLARFGYIDYNPRLGNIMSQHDLSAAVMNFQRFAGLEQTGQLDHITLEKM DSPRCGNRDVVGSDAAARKKRYALQGSKWQKKHLTYKIASHTTDISRRDTENAINKAFKVWEAESGLTFRQVRSSKADIE IKFAEKAHGDGDPFDGPSKTLAHAFFPQFGGDAHFDEAEKWAVSADKGVSLFIVAAHEFGHSLGLSHSDVNQALMAPFYN PNYDGLHDDDIRAIRILYGSPSDKHRPQSSTTPPRTTRKPRPGITRQTTTTKTPPVGACNGRFDAITMVRNGTTYAFKGD KFWKLNDQGMEPGYPKSTKKIWGLSGKVDASLSFGAYTDLFQGDVIHRYINGIPMHGYPKRISEVYKGIPSKLDTAFVWS GNGKVYFVKGDKYWRYNPSLRKSDNGYPRPLSVWKGLPERLDAALKWKDRTYFFKNGYYWRFDDERVEVAQSLKTPYPRR SDAWWLGCTDNTLKSSPEETGIGDKNEDVNDGDGNGASSRFNTVPRAMLSTLLMFIVSMLLC >CAE1318974.1 MMP14 [Sepia pharaonis] MKQWRLNRIRSVHRNYDLLNSSVKMNEPEALSDFLRWVERTRHSGPNELFSARLGRTNCSLPAWVERTVLCLPGSNELFS ARLGSKWAKRDLTYKIQQVTPRLPRLKVEREIARAFKVWSEVTSLTFTQKDMDPVDIEVLFARNHHGDRHPFDGSGGTLA HAFFPQFGGDAHFDDSESWSVASRQGVNLFQVAAHEIGHSLGLAHSDVRNALMAPFYRGYIPNFKLSRDDVAAVQELYGG RTDTRRFDPPPNPLPTQGRVSRPPICNDASIDAITRLRDGTTHVFKGEEYYRLSRTGIDNGYPRKIHWDWRGVQGPIDAA VTWDDSFTFIFKDDKYWKFDGMKPVSGYPRKIREGFKGLPDKIDAAFVWSGNGKTYFIKGDRYWRWAKYGIDFGYPKQLN VWVNLPPRVTAAFKWQNGRTYFFNGDTYYRFNDKNFRVDDDYPRKVSYWWLGCADETQNQQVHDVHSVITTRPRYPDKPR TVHVSPTQDKDKDWKVIRKGNDNGGLRMQATRLMLAGSLFVAFLRHQ >XP_038060416.1 matrix metalloproteinase-19-like [Patiria miniata] MTGLTLLLTALLASAVTVIHSRPVENDFDAMTYLSYFGYLKRQTNDGTGMDEDEVRQGILDFQFMGNLTQTGVLDAPTME KMNMPRCGMPDNIGHAMDARRKKRFSLGSKWRNTDLTFRIDNTTPDIPNRADVDATMVAALKVWSDVTPLTFTRVTGNTP ADIVISFSPTDRDHGDGNPFDGPSGVLAHAFFPENGDAHFDEGERWTINSFSGINLFQVAAHEFGHSLGLGHSNVQGALM EAFYAGYVPNFQLHSDDILGIQAHYGIGSGGPDVTMAPNPPAPDIPCTGRVDAVTTTRDQSTYIFEGSNVWKFEMGASRI SAGFPKSISSTFVGVPDNIDAAFYYPMYRSTFIFKGSQYWRFDNEVMDANFPRSITGDWGLPGDLDAAFVWSGNNQVYFI KGNEYYRYNGRAVDANYPRDLSVWNVPGNQVTAAVQWTNRVTYFFTPSGGYYRYNDRNFRVEGGRGYPAPVASDWQGCAN TIEAATPTADSGVSGLAPSLLAMMLPVVLGTTYC >XP_031552385.1 uncharacterized protein LOC116289580 [Actinia tenebrosa] METLTTWLLFRFILLSVSSVLVYTHVQVNQRSRCAVRDSMKIHPELARTPTAGFSFMSTIDSKLITRSRSQGDKDAFNAL FNEKFKCHEKYVIPVAWHVIHSTSGEGKVAKETLEKQVXVLNDAFVRTPMIFNMSSVDYTANDAWVKNCLAMSPDFMRAL SQSPSSTLNLYTCKFSVLESTIGSAAMPWWYEEDSVYHGIVVHPDTLPGGSYAPINEGKNTVHEVGHYFGLFHVFEGECN NMDDGVHDTPRSKPSYGCPSTDTDTCPEQPGKDPVRNYMGYTNDACMTEFTTGQIERMKWALEKYRPSLMKMPQQPCTID AIFRWSNGYVYLFSGSNYYRYNESRPGLDPGYPRSITSHWPGVPSDIDGVFRYGNGITYFFKGKYYFRYNDTSSRVDPGF PRLINDFWRGVPSDIDDVISSANSYTYFFKGSQYYRFNPKTRHVDEGYPKAISDYWVDVPKDIEAAISWYNGGVYFFKDA QFWFFLHGNKAVGVPHGYPKPVREWWQGTMELSWYTLFRHCNGFTYFFQGNQYWRFNDNLYHVDFQYPKPITSSWTGLPT NIDTGFMWSNKRMYFFKGTKYFRFNVTAGELDLGYPKPIVYFWKGVPHGLDAVFRYVNGITYFFKGSEYYRFNDTTFQID QGYPRPIGNFWKGIPDNIDSVFVWSNGHTYFFKGSLYYRFNCETKQVDQGYPKSISRWRGMLYQP >NP_001333542.1 ZnMc domain-containing protein [Caenorhabditis elegans] MTVWRRWWYLYILSGFIINNVMLESKSRVKRYSIEGSYWGKSVITYRLKQPSQRMSLSQQKAVFARAFATWEEHTRLWFV AVDDEDEQKANIDIVFAAGDHEDGEPFDGKGNILAHAFFPRYGGDVHFDEDELWSANKTKGVDLYAVAVHEIGHSLGLKH SSNHLSIMAPFYKQYTGAVMHLHQDDISAVKRLYGAPVKIRKKASEHHIWRSELCTKPYLDAVTTLKNGTILAFRGKMFF ELKTTRKWLLPRKINRIFPFEGPLEAATTDRHGNVYFFKKDTYWVMTKHGDMMNGYPKKISQGLTDTPDGINAALYYHED GKPYFFKKSYFWQYSRYGKHKLWPRAIVSIFENQNSPPEIDAAFQLNNTSSFLFHQNKYWKVSGDPMRIEKGFPRSLSRD WFNCL >XP_781575.3 matrix metalloproteinase-2 isoform X1 [Strongylocentrotus purpuratus] MVDISSSVSSTFTCMRATMTFISVAVVIIFHLAVNSDALPMRDAQDAKMYLMNYGYLKQSDMANGQLTTEGDVVKALKQF QYMANIDETGTLDNDTMRMMKMPRCGMPDMVGTGSHDVRKKRFTLSQLKWPYTDLTYRLDGTTPDLPAALVNQIMALALK AWSDVSSLTFAQVAADQPADILIDFFEADHGDGNPFDGPGAVLAHAYFPNPNPIAGDAHFDDAETYTDGIPQGINLFQVA AHEFGHSLGLGHSTIDAALMAPFYQGYVPDFELHPDDVAGIQAHYGQNTNQAGGGDDGDAAPPTPPASGDCISQFTATTQ TADGGFYFINDTHAFRIGPNGLEAGYPKTIATEFPGLPNNIDAGLFFQDNGKTYFFKGGDYYQFSSQTMDDGYPQAIATA FPGLPDDLDSAFVWTGNGRVYFTKGDQYYRFSAGVGVDDGYPRPLSLWTNLPPTLDAAMQHANGFTYFFSGDFYYRFNDD EFKVDAGYPRDTSVGWLGCAAAIGSGNVTVSPPGGGSTALTSAGLPSLLLVILIICSLYLADLCVLVNL
Mafft alignment of selected proteins >sp|P04004|VTNC_HUMAN Vitronectin OS=Homo sapiens OX=9606 GN=VTN PE=1 SV=1 --------------MAP-LRPLLI------------------------------------ ---------------------------------LALLAWVALADQESCKGRCTEGF---- -NVDK-----------------------------KCQCDELCSYYQSCCTDYTAECKPQV T--------------------RGDVF-TM------PEDEYTV------------------ ---------------Y--------------------DDGEE-----KNNATVHEQVGG-- ----PSLTSDL---------------------QAQSKGNPEQ------------TPVLKP EEEAPAPEVGASKPEGIDSRPETLHPGRPQPP------------AEEELCSGKPFDAFTD LKNGSLFAFRGQYC--YELDEK--AVRPGYPKLIRDVW-GIEGPIDAAFTRINCQGKTYL FKGSQYWRFE--DGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQY WEYQFQHQPSQEEC---EGSSLSAVFEHFAMMQRD------------------------- -------------------------SWEDIFELL--FWGRTSAGT-------------RQ PQFISRDW--HGVPGQVDAAMA---GRIYISGMAPRPSLAKKQRFRHRNRKG--YRSQRG --------------HSRG--------RNQN------------------------------ ---SRRPSRATWLSLFSS-EESNLGA-NNYDDYRMDWLVPAT-------------CEPIQ SVFFFS-GDKYYRVNLRTRRVDTV-DPPYPRSIAQY-WLGCPAPGHL------------- ------------------------------------------------------------ --------------------------------------- >NP_035837.1 vitronectin precursor [Mus musculus] --------------MAP-LRPFFI------------------------------------ ---------------------------------LALVAWVSLADQESCKGRCTQGF---- -MASK-----------------------------KCQCDELCTYYQSCCADYMEQCKPQV T--------------------RGDVF-TM------PEDDYWS------------------ ---------------Y--------------------DYVEEP----KNNTNTGVQPEN-- ----TSPPGDL---------------------NPRTDGTLKP------------TAFLDP EEQPSTPAPKVEQQ-EEILRPDTTDQGTPEFP-------------EEELCSGKPFDAFTD LKNGSLFAFRGQYC--YELDET--AVRPGYPKLIQDVW-GIEGPIDAAFTRINCQGKTYL FKGSQYWRFE--DGVLDPGYPRNISEGFSGIPDNVDAAFALPAHRYSGRERVYFFKGKQY WEYEFQQQPSQEEC---EGSSLSAVFEHFALLQRD------------------------- -------------------------SWENIFELL--FWGRSSDGA-------------RE PQFISRNW--HGVPGKVDAAMA---GRIYVTGSLSHSAQAKKQKSKRRSRKR--YRSRRG --------------RGHRRS------QSSN------------------------------ ---SRRSSRSIWFSLFSS-EESGLGT-YNNYDYDMDWLVPAT-------------CEPIQ SVYFFS-GDKYYRVNLRTRRVDSV-NPPYPRSIAQY-WLGCPTSEK-------------- ------------------------------------------------------------ --------------------------------------- >XP_043335857.1 vitronectin [Cervus canadensis] --------------MTS-LRPLLM------------------------------------ ---------------------------------LALLAWAVVADQESCKGRCAEGF---- -NATR-----------------------------KCQCDELCSYYQSCCADFMAECKPQV T--------------------RGDVF-HL------PEDEYRF------------------ ---------------Y--------------------DYNEAQ----TVNLSTEAQPES-- ----PNLAPVL---------------------QAQTQETPVE------------APVLSP EKEAPLPGRG-----DSEPEVGTSDPGISESP------------AEEETCSGKPFDAFTD LKNGSLFAFRGLYC--YELDEK--AVRPGYPKLIRDVW-GIEGPIDAAFTRVNCEGKTYL FKGSLYWRFE--DGVLEPDFPRNISDGFKGIPDDVDAALALPAHSYNGRERVYFFKGNHY WEYVFQQQPSQEEC---EGGSQPAAFKHFALMQRD------------------------- -------------------------SWEDIFRLL--FWGGPSGGA-------------GQ PRLISRDW--LGLPRRLDAAMA---GHIYVSGSAPSFPQAKMTKSARRHRKR--YRSLRN RG------------RGRGRG----RSRSQN------------------------------ ---PYRRSRSTWLSWFSS-EELGLGA-NNYDNYEMDWLVPAT-------------CEPIQ SVYFFS-EDKYYRVNLRTRRVDTV-IPPYPRSIAQY-WLGCPVPGHA------------- ------------------------------------------------------------ --------------------------------------- >KAF4012137.1 hypothetical protein G4228_003124 [Cervus hanglu yarkandensis] --------------MTS-LRPLLM------------------------------------ ---------------------------------LALLAWAVVADQESCKGRCAEGF---- -NATR-----------------------------KCQCDELCSYYQSCCADFMAECKPQV T--------------------RGDVF-HL------PEDEYRF------------------ ---------------Y--------------------DYNEAQ----TVNLSTEAQPES-- ----PNLAPVL---------------------QAQTQETPVE------------APVLSP EKEAPLPGRG-----DSEPEVGTSDPGISESP------------AEEETCSGKPFDAFTD LKNGSLFAFRGLYC--YELDEK--AVRPGYPKLIRDVW-GIEGPIDAAFTRVNCEGKTYL FKGSLYWRFE--DGVLEADFPRNISDGFKGIPDDVDAALALPAHNYNGRERVYFFKGNHY WEYVFQQQPSQEEC---EGGSQPAAFKHFALMQRD------------------------- -------------------------SWEDIFRLL--FWGGPSGGA-------------GQ PRLISRDW--LGLPRRLDAAMA---GHIYVSGSAPSFPQAKMTKSARRHRKR--YRSLRN RG------------RGRGRG----RSRSQN------------------------------ ---PYRRSRSTWLSWFSS-EELGLGA-NNYDNYEMDWLVPAT-------------CEPIQ SVYFFS-EDKYYRVNLRTRRVDTV-IPPYPRSIAQY-WLGCPVPGHA------------- ------------------------------------------------------------ --------------------------------------- >OWK14767.1 VTN [Cervus elaphus hippelaphus] --------------MTS-LRPLLM------------------------------------ ---------------------------------LALLAWAVVADQESCKGRCAEGF---- -NATR-----------------------------KCQCDELCSYYQSCCADFMAECKPQV T--------------------RGDVF-HL------PEDEYRF------------------ ---------------Y--------------------DYNEVQ----TVNLSTEAQPES-- ----PNLAPVL---------------------QAQTQETPVE------------APVLSP EKEAPLPGRG-----DSEPEVGTSDPGISESP------------AEEETCSGKPFDAFTD LKNGSLFAFRGLYC--YELDEK--AVRPGYPKLIRDVW-GIEGPIDAAFTRVNCEGKTYL FKGSLYWRFE--DGVLEPDFPRNISDGFKGIPDDVDAALALPAHNYNSRERVYFFKGNHY WEYVFQQQPSQEEC---EGGSQPAAFKHFALMQRD------------------------- -------------------------SWEDIFRLL--FWGGPSGGA-------------GQ PRLISRDW--LGLPRRLDAAMA---GHIYVSGSAPSFPQAKMTKSARRHRKR--YRSLRN RG------------RGRGRG----RSRSQN------------------------------ ---PYRRSRSTWLSWFSS-EELGLGA-NNYDNYEMDWLVPAT-------------CEPIQ SVYFFS-EDKYYRVNLRTRRVDTV-IPPYPRSIAQY-WLGCPVPGHA------------- ------------------------------------------------------------ --------------------------------------- >KAB0358735.1 hypothetical protein FD754_002891 [Muntiacus muntjak] --------------MTS-LRPLLM------------------------------------ ---------------------------------LALLAWAVVADQESCKGRCAEGF---- -NATR-----------------------------KCQCDELCSYYQSCCADFMAECKPQV T--------------------RGDVF-HL------PEDEYRF------------------ ---------------Y--------------------DYNEAQ----TVNLSVETQPES-- ----PTLAPVL---------------------QAQTQETPVQ------------APVLSP EKEAPLPGRG-----DSEPEVGTTD------P------------AEEETCSGKPFDAFTD LKNGSLFAFRGLYC--YELDEK--AVRPGYPKLIRDVW-GIEGPIDAAFTRVNCQGKTYL FKGSLYWRFE--DGVLEPDFPRNISDGFKGIPDDVNAALALPAHNYNGRERVYFFKGNHY WEYVFQQQPSQEEC---EGGSQPAAFKHFALMQRD------------------------- -------------------------SWEDIFRLL--FWGGPSGGA-------------GQ PRLISRDW--LGLPRRLDAAMA---GHIYVSGSAPSFPQAKMTKSARRHRKR--YRSLRS --------------RGRGRG----RSRSQN------------------------------ ---PYRRSRSTWLSWFSS-EELGLGA-NNYDNYEMDWLVPAT-------------CEPIQ SVYFFS-EDKYYRVNLRTRRVDTV-IPPYPRSIAQY-WLGCPVPGHA------------- ------------------------------------------------------------ --------------------------------------- >KAB0367524.1 hypothetical protein FD755_020848 [Muntiacus reevesi] --------------MTS-LRPLLM------------------------------------ ---------------------------------LALLAWAVVADQESCKGRCAEGF---- -NATR-----------------------------KCQCDELCSYYQSCCADFMAECKPQV T--------------------RGDVF-HL------PEDEYRF------------------ ---------------Y--------------------DYNEAQ----TVNPSVETQPES-- ----PTLAPVL---------------------QAQTQETPVQ------------APVLSP EKEAPLPGRG-----DSEPEVETSD------P------------AEEETCSGKPFDAFTD LKNGSLFAFRGLYC--YELDEK--AVRPGYPKLIRDVW-GIEGPIDAAFTRVNCQGKTYL FKGSLYWRFE--DGVLEPDFPRNISDGFKGIPDDVDAALALPAHNYNGRERVYFFKGNHY WEYVFQQQPSQEEC---EGGSQPAAFKHFALMQRD------------------------- -------------------------SWEDIFRLL--FWGGPSGGA-------------GQ PRLISRDW--LGLPRRLDAAMA---GHIYVSGSAPSFPQAKMTKSARRHRKR--YRSLRS --------------RGRGRG----RSRSQN------------------------------ ---PYRRSRSTWLSWFSS-EELGLGA-NNYDNYEMDWLVPAT-------------CEPIQ SVYFFS-EDKYYRVNLRTRRVDTV-IPPYPRSIAQY-WLGCPVPGQA------------- ------------------------------------------------------------ --------------------------------------- >NP_001184010.1 vitronectin L homeolog precursor [Xenopus laevis] --------------MKVLLFPALLLL---------------------------------- ---------------------------------LGAVR-AAHAAEESCAGRCFSGF---- -DGNK-----------------------------KCQCDIICVHFESCCIDYLTLCKPKE Q--------------------RGDVF-EI------PEDEYNY------------------ ---------------------------------------DSG----TSEPELASKV---- --------------------------------NEELEETPDD--------------TTEP VENLPPKI------------EEVIQPDQMEES-------------QDELCSGQPFDAFTN IKNGSIYAFRGKYF--YELDDK--SALEGYPKLIKDVW-GIDGPVDAAFTRMNCQGKTYL FKGKEYWRFS--NGVLESDYPRNISEGFHDIPDNIDAAFALPANNHNDREKVYFFKGNKY WQYEFQNQPSRKDC---QDSAQSELFTYYVTLQKD------------------------- -------------------------SWEDFFSFL--FGPSMKRST-------------AG PWYINKDW--KGVPNNVDAVLP---SRIYVPKQT------------RRSRRR--KSRRRN -------------------------NRK-------------------------------- ---KSGGMRSLWSDFSFD-PLDGLFD-YDDEQSDPDWLPPER-PAD---------CQPTQ NVYFFK-NDKYYRVNLRTKRVDYV-YPPYPRSIAQY-WLGCKKDERLEKSRG-------- ------------------------------------------------------------ --------------------------------------- >XP_015807112.1 PREDICTED: vitronectin-like [Nothobranchius furzeri] --------------MR--LFIILL------------------------------------ ---------------------------------LALVA-DGLTEDESCLVRCENGF---- -DSER-----------------------------KCQCDSMCKYYSSCCKDYEALCG-MM T--------------------RGDTF-EF------AEDDYDLS----------------- --------------VITATS----------------DQHSTG----SQSPTAPSTP---- ----QPLVPDFSHRLRQSPEISLQMTRPPHLKN---HRVTPVSPP-------PKSEPSTV TSSPQTHTTAQ-----TTTVPTTKATTAAPDP-------------DAEVCSGRPFDAFMQ LKNGSIYAFRGKYF--FELDQK--SVLTGYPKLIKDVW-GIEGPIDAAFTRINCQGKTYI FKGNKYWRFD--NNELDDDYPRDISVGFDKIPDHVDAAFALPAHSHHGKEKVYFFKNDQY YVYEFLHQPSHEECAVMSERSPSALFRRYTDLYYN------------------------- -------------------------NYERFFHEL--FSDLPQHH--------------DK HHFINKDW--KGLKSPVDAAMS---GRIYITTGR--------SMPRRYDYQ---PDQQGG ---GRQWGQQNGWQRG-QRR----WNRSPHWGSAAEQGLNMGQRFAERGMEMGMRLAERR MEMEDRLGRDWDRRWDQDWDQDRRWD-RYNQNNRGNYDSRND-RSF-------LRDMPIQ SVYFFK-ADKYYRVDLRTKRVDPA-MPPYPRSIAKY-WLGCSDTTGAEKK---------- ------------------------------------------------------------ --------------------------------------- >XP_021337086.1 vitronectin isoform X1 [Danio rerio] --------------MRV---FLLL------------------------------------ ---------------------------------LVLLS-FADAAEESCIERCENGF---- -DATK-----------------------------SCQCDSMCTYYKSCCTDYESLCRIKA ---------------------RGDTFPSH------PEDDYDE------------------ ---------------------------------------ETN----STEVPIRSRPQVRV LSPSPLEISSM--------------VTP--VLDTANEPTPVV------------ATAATP TNKNPATTPGA-----TTTAQPT--PTKAKDP-------------DAEVCSGRPFDAFMQ LKNGSIYAFRGEYF--FELDEK--SVLPGYPKLIEDIW-GIKGPIDAAFTRINCQGKTYI FKGNKYWRFD--DGVLDDDFPRDIAVGFEKIPDHLDAAFATPAHSHHGKEKVYFFKGDQY YHYEFKHQPSHEECIKMSLRSPSMLFRRYTDIYYD------------------------- -------------------------RWTEHFNQL--FGGAQSHH---------------G HHFINRDW--IGIKSPVDAVLV---GRLYVTPRW--------QNRRRQDRNRQDWDQQQG QQYGQQWDQRYGQQWGSRRR----QNRSPYWESMAERGISIGQEF--------------- ---SQRFGQD---RWR---DQDRRRDYYYDRQNDYDYDYRYK-PTEDIVYNILRRSQPLQ SVYFFK-GDKYYRVNLQTKRVDYA-NPPYPRPIGKY-WLGCKDTSGAEKR---------- ------------------------------------------------------------ --------------------------------------- >XP_030260427.1 vitronectin-like [Sparus aurata] --------------MR--LWAILL------------------------------------ ---------------------------------LALLA-QALAEDKSCMGRCENGF---- -NSER-----------------------------KCQCDSMCKYYKSCCSDYEVTCG-MT T--------------------RGDTY-VS------ADDDDEL------------------ ---------------FEGTT----------------PSPFTP----SPFTPSPSTATSRQ LRPKQQAISDFGRRGQQRHETTLEMTRPPRLMDTIIQRIPVIQRT-------PISEAVTP TQDVASTTKAP-----QTTVPSTTGTTAAPDP-------------DAVVCSGRPFDSFMQ LKNGSIYAFRGDYF--FELDQK--SVLPGYPKLIKDVW-GIRGPIDAAFTRVNCQGKTYI FKGNQYWRFD--NGVLDDDYPRDISVGFDKIPDHVDAAFALPAPGHNGKEKVYFFKGEQY YTYEFLHQPSHEECITMSESSPSTLFRRYTDIYYN------------------------- -------------------------NYERSLSEL--FSDLPQHH--------------DK HHFIEKDW--KGLKAPLDAVMT---GRMYVPPLR--------STPRRNDYR---YDQQYG QQYGQQYGQQWDQQWG-RRR----QSRSPNWGSMAERGMNMGQGFAERGMEMGLRLAEKR MEMEERLGRDWDRRWDQDWDQDRRRD-GHRQNNRGNYDSRSYLEPI-------RREQPIQ TVYFFK-GDKYYRVDLRTKRVDPG-SPPYPRSIAKY-WLGCSDTAGAEK----------- ------------------------------------------------------------ --------------------------------------- >XP_023818375.1 vitronectin [Oryzias latipes] --------------MKPALALLSL------------------------------------ ---------------------------------LLVVE-STSAAEESCVGLCG-SF---- -DPER-----------------------------KCQCDSMCVYYSSCCGDFSNICAKKV T--------------------RGDVF-GS------VENTTA------------------- ----------------------------------------------IVTPNVSSAAPT-- -------------------------------VQSSSAPQPTS------------------ ----------------------TFGPTAHTDP-------------DAAPCSGRPFDAFLQ LKNGSIYAFRGDYF--FELDDD--SILPGYPKLIQDAW-GISGPISAAFTRINCQGKSYI FKGSRYWRYN--GNVLDEGFPRDISEGFQDIPNDIDAAFTVPAPNHRGKEKAYFFKGDKY YKYEFKHQPSHEECVQMTKASPSVLFTQYTDLFCD------------------Q------ -------------------------TAEDLFTGL--FGSSFDSQR-------------TN PRFISGDW--HGIRPPVDAAVV---GRVHLSVKPTA------SPPRRGSSRR-------- --------------RGSSRR------RGPH------------------------------ ---RRRLSHRWFGDLWND-DD------FAFSMDESDFTDQST-TTD-------NRQIPVQ NVYFFK-KDKYYRVGLRSKRVDFA-NPPYPRSIAKY-WLGCKEEEMPDSSRAEKK----- ------------------------------------------------------------ --------------------------------------- >NP_062029.2 vitronectin precursor [Rattus norvegicus] --------------MAS-LRPFFI------------------------------------ ---------------------------------LALLALVSLADQESCKGRCTQGF---- -MASK-----------------------------KCQCDELCTYYQSCCVDYMEQCKPQV T--------------------RGDVF-TM------PEDEYWS------------------ ---------------Y--------------------DYPEET----KNSTSTGVQSEN-- ----TSLHFNL---------------------KPRAEETIKP------------TT-PDP QEQSNTQEPEVGQQ-GVAPRPDTTDEGTSEFP-------------EEELCSGKPFDAFTD LKNGSLFAFRGEYC--YELDET--AVRPGYPKLIQDVW-GIEGPIDAAFTRINCQGKTYL FKGSQYWRFE--DGVLDPDYPRNISEGFSGIPDNVDAALALPAHSYSGRERVYFFKGKQY WEYEFQQQPSQEEC---EGSSLSAVFEHFALLQRD------------------------- -------------------------SWENIFELL--FWGRSSDGA-------------KG PQFISRDW--HGVPGKVDAAMA---GRIYITGSTFRSVQAKKQKSGRRSRKR--YRSRRG --------------RGHSRS----RSRSMS------------------------------ ---SRRPSRSVWFSLLSS-EESGLGT-YNY-DYDMNWRIPAT-------------CEPIQ SVYFFS-GDKYYRVNLRTRRVDSV-NPPYPRSIAQY-WLGCPTSEK-------------- ------------------------------------------------------------ --------------------------------------- >NP_990392.1 vitronectin precursor [Gallus gallus] --------------MRL-LLPVLV------------------------------------ ---------------------------------LALLA-LTRAAEDSCEGRCDEGF---- -NAMK-----------------------------KCQCDTLCNYYQSCCSDYSTVCKAKV T--------------------RGDVF-AL------PEDDYLD------------------ ---------------Y--------------------DLSIDTG---TVGPTEAPAPTE-- ----HPTEPHS-------------SPSPTRVIDTATEETPEEP----------EVPTLHP TTTTTTTT------------SDETRNPSLDDE-------------PEELCSRKPFNAFTD LKNGSIYAFRGKYF--YELDKS--SVRPGYPKLISDVW-GIEGPIDAAFTRINCQGKTYL FKGSQYWRFD--DGALDPGYPRDISEGFEGIPNDIDAAFALPAHSYHGNERVYFFKGKYY WSYDFAHQPTQAEC---EKSSPSTVFNHYAFMNRD------------------------- -------------------------SWEDIFLSL--FGSRMVGA--------------SS QRLISRDW--RGVPNQLDAAMA---GRIYVSSRQPR------RRSSRRHRKR--YRNHRT ------------------------------------------------------------ ------LNLGLW-SWLNS-DSES-------TDTESDWLSGSQ-------------CETLQ SVYFFV-GDKYYRVNLRTKRVDLV-QPPYPRSIAQY-WLDCPQPDEEST----------- ------------------------------------------------------------ --------------------------------------- >NP_999269.1 vitronectin precursor [Sus scrofa] --------------MAP-LRPLLM------------------------------------ ---------------------------------LALLAWVALADQESCKGRCTDGF---- -IAER-----------------------------KCQCDELCSYYQSCCTDYVAECKPQV T--------------------RGDVF-LQ------PDDEYRA------------------ ---------------Y--------------------DYHEET----RHNTSVQEEQRI-- --------PVL---------------------LAKTEE----------------TPVLKP EEEAPPPG------------PQTDDLGVP----------------EEELCSGKPFDAFTN LKNGSVFAFRGLYC--YELDEK--AVRPGYPKLIQDVW-GIKGPIDAAFTRINCQGKTYL FKGSQYWRFD--DGVLDPNYPREISEGFKGIPDDVDAALALPAHSYSGRERVYFFKGKQY WEYVFQQQPSREEC---EGSSPSDVFAHFALMQRD------------------------- -------------------------SWEDIFRLL--FWSHSFGGA-------------IE PRVISQDW--LGLPEQVDAAMA---GQIYISGSALKPSQPKMTKSARRSGKR--YRSRRG --------------RGRGRG----HSRSQK------------------------------ ---SHRQSRSTWLPWFSS-EETGPGG-YNYDDYKMDWLVPAT-------------CEPIQ SVYFFS-GEEYYRVNLRTQRVDTV-TPPYPRSIAQY-WLGCPVPDQK------------- ------------------------------------------------------------ --------------------------------------- >XP_854040.1 vitronectin [Canis lupus familiaris] --------------MAF-PRPLLV------------------------------------ ---------------------------------LALLAWVVLADQESCKGRCTEGF---- -NADR-----------------------------KCQCDELCSYYQSCCEDYVAECKPQV T--------------------RGDVF-AL------PEDEYGV------------------ ---------------I--------------------DDHEGT----RE-QSVLTQLES-- ----TTLSPGL---------------------QAQSEKFPAQ------------VPILIP EEEAPGPGQG-------TLVLEAPDQDISESA------------AEEELCSGKPFDAFTD LKNGSLFAFRGQYC--YELDEK--AVRPGYPKLIRDVW-GIEGPIDAAFTRINCQGKTYL FKGSQYWRFE--DGVLDPDYPRNISEGFKGIPDNVDAAFALPARSYSGRERVYFFKGRQY WEYEFQQQPSQEEC---EGSSLSTVFEHFALLQRD------------------------- -------------------------SWETFFELL--FWNRPSGGA-------------GE PGFISQDW--PGLPRQVDAAMA---GRIYISGSAPR-SWVKKLNPKRRNRKR--YRSRRN --------------RGRG--------RSRT------------------------------ ---SQRQSRSAWLSWFSS-EESGLDT-YNYDDYNMDWLVPAT-------------CEPIQ SVYFFS-EDKYYRVNLRTRRVDTV-SPPYPRSIAQY-WLGCSAPSPQ------------- ------------------------------------------------------------ --------------------------------------- >NP_001030222.1 vitronectin precursor [Bos taurus] --------------MTS-LRPLLM------------------------------------ ---------------------------------LALLAWVVVADQESCKGRCTEGF---- -NATR-----------------------------KCQCDELCSYYQSCCADFMAECKPQV T--------------------RGDVF-HL------PEDEYGF------------------ ---------------H--------------------DYSDAQ----TVNSNVEAQPES-- ----TTLAPVL---------------------QAQTLETPVQ------------APVLNP EKEVPPSGRG-----DSEPGMGTSDLGTSESP------------AEEETCSGKPFDAFTD LKNGSLFAFRGLYC--YELDEK--AVRPGYPKLIRDVW-GIEGPIDAAFTRVNCQGKTYL FKGSQYWRFQ--DGVLEPDFPRNISDGFGGIPDDVDAALALPAHNFNGRERVYFFKGNHY WEYVFQQQPSQEDC---EGSSLPAAFKHFALMQRD------------------------- -------------------------SWVDIFRLL--FWGGSYGGA-------------GQ PQLISRNW--FGLPGRLDAAMA---GHIYVSGSAPSFPRAKMTKSARRHRKR--YRSLRS --------------RGRGRG------RNQN------------------------------ ---PYRRSRSAFLSWLSS-EELGLGA-NNYDSFEMDWLVPAT-------------CEPIQ SVYFFS-EDKYYRVNLRTRRVDAV-IPPYPRSIAQY-WLGCPVPGQA------------- ------------------------------------------------------------ --------------------------------------- >XP_001146856.1 vitronectin [Pan troglodytes] --------------MAP-LRPLLI------------------------------------ ---------------------------------LALLAWVALADQESCKGRCTEGF---- -NADK-----------------------------KCQCDELCSYYQSCCTDYTAECKPQV T--------------------RGDVF-TM------PEDEYTV------------------ ---------------Y--------------------DDGEE-----KNNATVHEQVGG-- ----PSLTSDL---------------------QAQSEGNPEQ------------TPVLKP EEEAPAPEVGASKPEGIDSRPETLHPGRPQPP------------AEEELCSGKPFDAFTD LKNGSLFAFRGQYC--YELDEK--AVRPGYPKLIRDVW-GIEGPIDAAFTRINCQGKTYL FKGSQYWRFE--DGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQY WEYQFQHQPSQEEC---EGSSLSAVFEHFAMMQRD------------------------- -------------------------SWEDIFELL--FWGRTSAGT-------------RQ PQFISRDW--HGVPGQVDAAMA---GRIYISGMAPRPSLAKKQKFRHRNRKG--YRSQRG --------------HSRG--------RNQN------------------------------ ---SRRPSRATWLSLFSS-EESNLGA-NNYDDYRMDWLVPAT-------------CEPIQ SVFFFS-GDKYYRVNLRTRRVDTV-DPPYPRSIAQY-WLGCPAPGHL------------- ------------------------------------------------------------ --------------------------------------- >NP_001075761.1 vitronectin precursor [Oryctolagus cuniculus] --------------MAP-LRPIFT------------------------------------ ---------------------------------LALLLWVVLADQESCKDRCTEGF---- -NANR-----------------------------KCQCDELCSYYQSCCADYAAECKPQV T--------------------RGDVF-TM------PEDEYGP------------------ ---------------Y--------------------DYIEQT----KDNASVHAQPESPT VGQEPTLSPDL---------------------QTEGGAEPTH------------EVPLEP EMETLRPE-------GEDLQAGTTELGTSASP------------AEEELCSGKPFDAFTD LKNGSLFAFRGQYC--YELDET--AVRPGYPKLIQDVW-GIEGPIDAAFTRINCQGKTYL FKGSQYWRFE--DGILDPDYPRNISEGFSGIPDNVDAAFALPAHSYSGRERVYFFKGDKY WEYQFQQQPSQEEC---EGSSLSAVFEHFAMLHRD------------------------- -------------------------SWEDIFKLL--FWGRPSGGA-------------RQ PQFISRDW--HGVPGKVDAAMA---GRIYISGLTPS-PSAKKQKSRRRSRKR--YRSRYG --------------RG----------RSQN------------------------------ ---SRRLSRSISRLWFSS-EEVSLGP-YNYEDYETSWLKPAT-------------SEPIQ SVYFFS-GDKYYRVNLRTQRVDTV-NPPYPRSIAQY-WLGCPAPGGQ------------- ------------------------------------------------------------ --------------------------------------- >NP_001127063.1 vitronectin precursor [Pongo abelii] --------------MAP-LRPLLI------------------------------------ ---------------------------------LALLAWVALADQESCKGRCTEGF---- -NADK-----------------------------KCQCDELCSYYQSCCTDYTAECKPQV T--------------------RGDVF-TM------PEDEYSV------------------ ---------------Y--------------------DDGEE-----KNNATVHEQLGG-- ----PSLTPDF---------------------QAQPEGNPEQ------------APVLKP EEEAPAPEVGTSRPEGMDSRPETLHPGRPQPP------------AEEELCSGKPFDAFTD LKNGSLFAFRGQYC--YELDEK--AVRPGYPKLIRDVW-GIEGPIDAAFTRINCQGKTYL FKGSQYWRFE--DGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQY WEYQFQHQPSQEEC---EGSSLSAVFEHFAMIQRD------------------------- -------------------------SWEDIFELL--FWGRTSAGT-------------RQ PQFISRDW--HGVPGQVDAAMA---GRIYISGMAPRPALAKKQKFRRRNRKG--YRSHRG --------------HSRG--------RNQN------------------------------ ---SRRPSHAMWLSLFSS-EDSNLGA-NNYDDYRMDWLVPAT-------------CEPIQ SVFFFS-GDKYYRVNLRTRRVDAV-DPPYPRSIAQY-WLGCPAPGHL------------- ------------------------------------------------------------ --------------------------------------- >XP_003211803.2 vitronectin [Meleagris gallopavo] --------------MRL-LLLVLV------------------------------------ ---------------------------------LALLA-PTRAAEDSCEGRCDEGF---- -NALK-----------------------------KCQCDNLCNYYQSCCSDYSTVCKAKV T--------------------RGDVF-AL------PEDDYLD------------------ ---------------Y--------------------DLPIDTG---TEGPTGAPAPTE-- ----HPTEPHT-------------FPLPTRETDTATEETPVET----------EVPTLHP TTTTTTTT------------SEGTRNPSLEDE-------------PEKLCSRKPFNAFTD LKNGSLYAFRGKYF--YELDES--SVRPGYPKLISDVW-GIEGPIDAAFTRINCQGKTYL FKGNKYWRFD--DGALEPGYPRDISEGFEGIPNDIDAAFALPAHSYHGNERVYFFKGKYY WSYDFAHQPTQAEC---DKSSPSTVFNHYAFMNRD------------------------- -------------------------SWEDIFFSL--FGSRMVGA--------------SS PRLISRDW--RGVPNQLDAAMA---GRIYVSSRQPR------RRNSRRHRKR--YRNHRT ------------------------------------------------------------ ------LNLGFW-GWLNN-DSES-------TDTESDWLSGSQ-------------CETLQ SVYFFV-GDKYYRVNLRTKRVDLV-QPRYPRSIAQY-WLDCPQPDEEST----------- ------------------------------------------------------------ --------------------------------------- >XP_005693309.1 PREDICTED: vitronectin [Capra hircus] --------------MTS-LRPLLM------------------------------------ ---------------------------------LALLVWVVVADQESCKGRCTEGF---- -NATR-----------------------------KCQCDELCSYYQSCCADFMAECKPQV T--------------------RGDVF-HL------PEDEYGT------------------ ---------------Y--------------------DYGEVQ----TVNRSVEAQPES-- ----PTLAPVL---------------------QA---EIPVQ------------APVLNP EKEAPSPGRG-----DSDPGLGTSDLGTSESP------------AEEETCSGKPFDAFTD LKNGSLFAFRGLYC--YELDEK--AVRPGYPKLIRDVW-GIEGPIDAAFTRFNCQGKTYL FKGSQYWRFE--DGVLEPDFPRNISDGFKGIPDDVDAALALPAHSYNGRERVYFFKGNHY WEYVFQQQPSREEC---EGSSQPAAFKHFALMQRD------------------------- -------------------------SWEDIFRLL--FWGGSFGGA-------------GQ PQLISRDW--FGLPGKLDAAMA---GHIYISGSAPSSPRAKMTKSARRHRKR--YRSLRS --------------RGRGRG----RARSQN------------------------------ ---PYRRFRSTWLSWFSS-EELGLGA-DNYDNYEMDWLVPAT-------------CEPIQ SVYFFS-EDKYYRVNLRTRRVDSV-IPPYPRSIAQY-WLGCPVPGHA------------- ------------------------------------------------------------ --------------------------------------- >XP_003812709.1 vitronectin [Pan paniscus] --------------MAP-LRPLLI------------------------------------ ---------------------------------LALLAWVALADQDSCKGRCTEGF---- -NADK-----------------------------KCQCDELCSYYQSCCTDYTAECKPQV T--------------------RGDVF-TM------PEDEYTV------------------ ---------------Y--------------------DDGEE-----KNNATVHEQVGG-- ----PSLTSDL---------------------QAQSEGNPEQ------------TPVLKP EEEAPAPEVGASKPEGIDSRPETLHPGRPQPP------------AEEELCSGKPFDAFTD LKNGSLFAFRGQYC--YELDEK--AVRPGYPKLIRDVW-GIEGPIDAAFTRINCQGKTYL FKGSQYWRFE--DGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQY WEYQFQHQPSQEEC---EGSSLSAVFEHFAMMQRD------------------------- -------------------------SWEDIFELL--FWGRTSAGT-------------RQ PQFISRDW--HGVPGQVDAAMA---GRIYISGMAPRPSLAKKQKFRHRNRKG--YRSQRG --------------HSRG--------RNQN------------------------------ ---SRRPSRATWLSLFSS-EESNLGA-NNYDDYRMDWLVPAT-------------CEPIQ SVFFFS-GDKYYRVNLRTRRVDTV-DPPYPRSIAQY-WLGCPAPGHL------------- ------------------------------------------------------------ --------------------------------------- >XP_003996546.1 vitronectin [Felis catus] --------------MAS-PRPLLI------------------------------------ ---------------------------------LALLAWVVLADRESCKGRCTEGF---- -NADR-----------------------------KCQCDELCSYYQSCCEDYVAECKPQV T--------------------RGDVF-TL------PEDEYGV------------------ ---------------Y--------------------NYFEET----RDNSSVLPQPES-- ----TSQGPDL---------------------QAQTEVSPDQET--------FEEPLLNP TQETLGP--------------ETSDQDIPESP------------VVEELCSGKPFDAFTD LKNGSLFAFRGQYC--YELDEE--AVSPGYPKLIQDVW-GIEGPIDAAFTRINCQGKTYL FQGHQYWRFE--DGVLDPDYPRNISEGFKGIPDNVDAALALPAHSYSGRERAYFFKGRQY WEYEFQQQPSQEEC---EGSSLSAVFEHFALLQRD------------------------- -------------------------SWETLFEFL--FGNRFSGGA-------------GQ PRLISRDW--PGVPRQVDAAMA---GRIYISGSAPQ-SWAEKQKSRRRNRKR--YRSRRN --------------RGRG--------RSQN------------------------------ ---PHRQSRSAWLSWLSS-EEDSLGI-YNFRDYDMDWLVPAT-------------CEPIQ SVYFFS-GDKYYRVNLRTRQVDTV-SPPYPRSIAQY-WLGCPAPGHQ------------- ------------------------------------------------------------ --------------------------------------- >XP_027831040.1 vitronectin [Ovis aries] --------------MTS-LRPLLM------------------------------------ ---------------------------------LALLAWVVVADQESCKGRCTEGF---- -NATR-----------------------------KCQCDELCSYYQSCCADFMAECKPQV T--------------------RGDVF-HL------PEDEYGT------------------ ---------------Y--------------------DYGEVQ----TVNRSVEAQPES-- ----PTLAPVL---------------------QA---EIPVQ------------APVLNP EKEAPSPGRG-----DSDPGLGTSDLGTSESP------------AEEETCSGKPFDAFTD LKNGSLFAFRGLYC--YELDEK--AVRPGYPKLIRDVW-GIEGPIDAAFTRFNCQGKTYL FKGSQYWRFE--DGVLEPEFPRNISDGFKGIPDDVDAALALPAHSYNGRERVYFFKGNHY WEYVFQQQPSQEEC---EGSSQPAAFKHFALMQRD------------------------- -------------------------SWEDIFRLL--FWGGSFGGA-------------GQ PQLISRDW--FGLPGKLDAAMA---GHIYISGSAPSSPRAKMTKSARRHRKR--YRSLRS --------------RGRGRG----RGRSQN------------------------------ ---PYRRFRSTWLSWFSS-EELGLGA-DNYDNYEMDWLVPAT-------------CEPIQ SVYFFS-EDKYYRVNLRTRRVDSV-IPPYPRSIAQY-WLGCPVPGHA------------- ------------------------------------------------------------ --------------------------------------- >XP_004042098.1 vitronectin [Gorilla gorilla gorilla] --------------MAP-LRPLLI------------------------------------ ---------------------------------LALLAWVALADQESCKGRCTEGF---- -NADK-----------------------------KCQCDELCSYYQSCCTDYTAECKPQV T--------------------RGDVF-TM------PEDEYTV------------------ ---------------Y--------------------DDGEE-----KNNATVHEQLGG-- ----PSLTSDL---------------------QAQSEQNPEQ------------TPVLKP EEEAPAPEVGSSKPEGVDSRPETLHPGRPQPP------------AEEELCSGKPFDAFTD LKNGSLFAFRGQYC--YELDEK--AVRPGYPKLIRDVW-GIEGPIDAAFTRINCQGKTYL FKGSQYWRFE--DGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQY WEYQFQHQPSQEEC---EGSSLSAVFEHFAMMQRD------------------------- -------------------------SWEDIFELL--FWGRTSAGT-------------RQ PQFISRDW--HGVPGQVDAAMA---GHIYISGMAPRPSLAKKQKFRHRNRKG--YRSQRG --------------HSRG--------RNQN------------------------------ ---SRRPSRATWLSLFSS-EESNLGA-NNYDDYRMDWLVPAT-------------CEPVQ SVFFFS-GDKYYRVNLRTRRVDTV-DPPYPRSIAQY-WLGCPAPGHL------------- ------------------------------------------------------------ --------------------------------------- >XP_013222293.1 vitronectin [Columba livia] --------------MKL-LFAVLA------------------------------------ ---------------------------------LALLA-AARAAEDSCEGHCDDGF---- -DARR-----------------------------KCQCDTLCVYYQSCCSDYSTACKAKV T--------------------RGDVF-AL------PEDDYLD------------------ ---------------Y--------------------NLTVDL----GTEPSTKAAPTE-- ----LPTTPLP--------------------VQPTPESEPGPE----------ETLTETP MEEVPSTT------------ADGLGERDPEEE-------------PEELCSGKPFNAFTD LKNGSLYAFRGKYF--YELDET--SVRPGYPKLISDVW-GIEGPIDAAFTRINCQGKTYL FKGSQYWRFD--DGALDPGYPRNISDGFEGIPNSIDAAFALPAHSYHGNERVYFFKDKYY WSYDFAQQPTQADC---EKSSPSTVFNHYAFMNRD------------------------- -------------------------SWEDVFHIL--FGGRITGA--------------SS PRYISRDW--QGVPGRQD-----------LRGHPPAP----------------------- ------------------------------------------------------------ -------------------QEEV--------------------------------SPPAQ EVQ----------------------EPP----VTEFGFLGLAGK---------------- ------------------------------------------------------------ --------------------------------------- >XP_025070384.1 vitronectin [Alligator sinensis] --------------MGL-LLPAVL------------------------------------ ---------------------------------LGLFG-VALAAEESCAGRCDVAF---- -NSSM-----------------------------KCQCDPLCVYYQSCCSDYNSVCKTKV T--------------------RGDVF-AF------PEDDYSY------------------ ---------------FYGNK---------------GDPFDQG----TGSPDVATTFPA-- --------PST---------------------SEMWTEEPTQQ----------WELSTDP SVT-------------TEALPATVEDWNQDEE-------------QEEACSGKTFDAFTD LKNGSIFAFRGKYF--YELNET--SVMPGYPKLIRDVW-GMDGPIDAAFTRINCQGKTYI FKGSQYWRFD--DGALDPGYPLNISEGFEGIPDDLDAAFALPAENYADNERVYFFKGRHY WSYEFAQQPTWEECE--EQDSQSAAFWHFAFLVGT------------------------- -------------------------DWDDIFDMP--FGLSSSKCR--------------- -----GAW--GGEAWECELS---------------------------------------- ------------------------------------------------------------ ------PSRRFW-PWLQD-DSES-------WELDSDWVYMGT------------RCQPVQ SIYFFV-GDKYYRVNLKTMRVDWV-HPRYPRPVAQY-WLGCPRLEPKRP----------- ------------------------------------------------------------ --------------------------------------- >XP_020740434.1 vitronectin isoform X1 [Odocoileus virginianus texanus] --------------MIS-RRPLLM------------------------------------ ---------------------------------LALLAWAAVADQESCKGRCAEGF---- -NATR-----------------------------KCQCDELCSYYQSCCADFMAECKPQV T--------------------RGDVF-HL------PEDEYRF------------------ ---------------Y--------------------DYNEEQ----TVNLSVEAQPES-- ----PTLAPVL---------------------QAQTQETPVQ------------APVLSP EKEAPLLGRG-----DSEPEVETSDPEISESP------------AEEETCSGKPFDAFTD LKNGSLFAFRGLYC--YELDEK--AVRPGYPKLIQDVW-GIEGPIDAAFTRVNCQGKTYL FKGSLYWRFE--DGVLEPDFPRNIADGFKGIPDDVDAALALPAHSYNGRERVYFFKGNHY WEYVFQQQPSQEEC---EGSSQPAAFKHFALMQRD------------------------- -------------------------SWEDIFRLL--FWGGPSGGA-------------GQ PRLISRDW--LGLPRRLDAAMA---GHIYVSGSAPSFPQAKMTKSARRHRKR--YRSLRS --------------RGRGRG----RSRSQN------------------------------ ---PYRRSRSTWLSWFSS-EELGLGA-NNYDNYEMDWLVPAT-------------CEPIQ SVYFFS-EDKYYRVNLRTRRVDTV-IPPYPRSIAQY-WLGCPVPGHA------------- ------------------------------------------------------------ --------------------------------------- >XP_040194287.1 vitronectin [Rana temporaria] --------------MRALLLPAIL-L---------------------------------- ---------------------------------LGAID-SALPAEESCVGRCLEGF---- -NAKI-----------------------------KCQCDDLCIYYGSCCSDFNVVCVKKE T--------------------RGDVF-TF------PEDEFDN------------------ ---------------FND----------------------------TTDPNPLTQ----- --------------------------------ETTPVDKPGEA----------ETVTERP TKG-----------------TTTVDP-VTDDI-------------PEELCSGKPFDAFTN LKNGSIYAFRGEYF--YELDDK--KALDGYPKRIKDVW-GIEGPIDAAITRMNCEGKTYI FKGTQYWRFS--DGVLDSDYPRDIDVGFKNIPNDIDAAFALPANNYQGKERAYFFKGRQY WQYEFTQQPTREEC---LGSPPSEIFTRYAAMQDD------------------------- -------------------------SWEDIFSLL--FGKLFTGNS-------------AE PKSISRDW--RGVPYGVNAVLP---SRIYIPQQK--------QPALRRSKRR--KSSRRK -------------------------NR--------------------------------- ---RRRPSKPSYYDFSDL------YD-FDDYEDDPDWLPPES-QPT---------CQPVQ SVFFFK-DDKYYRVNLQTKRVDYT-YPPYPRSIAEY-WLGCKKTSKQKKSRS-------- ------------------------------------------------------------ --------------------------------------- >NP_001189002.1 matrix metalloproteinase 1, isoform H [Drosophila melanogaster] --------------MTNCQSSVFIVVGTLFSIMAAAQSAPVSTTTQAEIYLSQFGYLPAS ARNPASSGLHDQRTWVSAIEEFQSFAGLNITGELDAET-MKLMSLPRCGVRDRVGT---- -GDSRSKRYALQGSRWRVKNLTYKISKYPKRLK-RVDVDAEIGRAFAVWSEDTDLTFTRK TSG------------------PVHIEIKF------VESEHGDGD---------------- --------------AFDGQGGTLAHAFFPV---FGGDAHFDD----AELWTIGSPRGTNL F---QVAAHEFGHSLGLSHSD-----------QSSALMAPFYRGFEPV-FK-LDEDDKAA IQSLYGRKTNQL----RPTNVYPATTQRPYSPPKVP--------LDDSICKDSKVDTLFN SAQGETYAFKGDKY--YKLTTD--SVEEGYPQLISKGWPGLPGNIDAAFTYK--NGKTYF FKGTQYWRYQ--GRQMDGVYPKEISEGFTGIPDHLDAAMV-----WGGNGKIYFFKGSKF WRFDPAKRPPVKAS---------------------------------------------- -----------------------------------------------------------Y PKPIS-NW--EGVPNNLDAAL--------------------------------------- ------------------------------------------------------------ -------------KYTNG------------------------------------------ YTYFFK-GDKYYRFHDARFAVDSA-TPPFPRPTAHW-WFGCKNTPSSTAVGDHQS--NDE PIVPE-------------------VAERTGNGAMSQSKLTSS----------SAVSTVIT ------------------TILMCLVSKLIV--------S >KAG6797835.1 Matrix metalloproteinase-14 [Apis mellifera caucasica] ------------------------------------------------------------ ------------------------------------------MTLPRCGVKDKVGP---- -GFGRSKRYALQGSRWRVKKLSYKISKYPRNLP-QHKVDAELNKAFKVWSEYTDLVFVQK KSG------------------QVHIEIRF------EKGEHGDGD---------------- --------------PFDGPGGTLAHAYFPV---YGGDAHFDD----AEQWTIDSFRGTNL F---QVAAHEFGHSLGLSHSD-----------VKSALMAPFYRGYEPY-FR-LDEDDIQG IQALYGTKTSNNGG--VPSGPKPTTTASPSEE-------------DSELCTNSKVDTMFN SAEGHMYVFKGDRY--WRLTSD--GVAIGYPKLISHSWKGLPGNIDAAFTYK--NGKTYF FKGSKYWRYV--GKKMDGDYPKEISEGFTGIPDNIDTVTV-----WTGNGKLYFYKGSKF WRFDPSQKPPVKNT---------------------------------------------- -----------------------------------------------------------Y PKLIS-NW--EGLPDNLDASI--------------------------------------- ------------------------------------------------------------ -------------VYRG------------------------------------------- YTYFFK-GDAYYRFNDRTFSVDIA-DPAFPRSTAYW-WFGCRSANKGTL----------- -----------------------------GNGSMNRWYNSQCNGNECLWFPENAINTFLN GGDFFIPDSVDGDNNDVGDIILDAGIKASFESDQILTSP >XP_039256216.1 matrix metalloproteinase-24-like [Styela clava] MK----------KGLYVVLTFVLLCATG---------AHPAPTQSKGVDFLARFGYIDYN ---PRLGNIMSQHDLSAAVMNFQRFAGLEQTGQLDHIT-LEKMDSPRCGNRDVVGSD--- -AAARKKRYALQGSKWQKKHLTYKIASHTTDIS-RRDTENAINKAFKVWEAESGLTFRQV RSS------------------KADIEIKF------AEKAHGDGD---------------- --------------PFDGPSKTLAHAFFPQ---FGGDAHFDE----AEKWAVSADKGVSL F---IVAAHEFGHSLGLSHSD-----------VNQALMAPFYN---PN-YDGLHDDDIRA IRILYGSPSDKHRP--QSSTTPPRTTRKPRPG--ITRQTTTTKTPPVGACN-GRFDAITM VRNGTTYAFKGDKF--WKLNDQ--GMEPGYPKSTKKIW-GLSGKVDASLSF---GAYTDL FQGDVIHRYI--NGIPMHGYPKRISEVYKGIPSKLDTAFV-----WSGNGKVYFVKGDKY WRYNPS-LRKSDNG---------------------------------------------- -----------------------------------------------------------Y PRPLS-VW--KGLPERLDAAL--------------------------------------- ------------------------------------------------------------ -------------KWKD------------------------------------------- RTYFFK-NGYYWRFDDERVEVAQSLKTPYPRRSDAW-WLGCTDNTLKSSPEETGI----- ---------------GDKNED---VNDGDGNGASSRFN--------------TVPRAMLS ------------------TLLMFIVSMLLC--------- >CAE1318974.1 MMP14 [Sepia pharaonis] --------------MKQWRLNRIRSVHR------------------------NYDLLNSS VK-------MNEPE---ALSDFLRWVERTRHSGPNELF-SARLGRTNCSLPAWVERTVLC LPGSNELFSARLGSKWAKRDLTYKIQQVTPRLP-RLKVEREIARAFKVWSEVTSLTFTQK DMD------------------PVDIEVLF------ARNHHGDRH---------------- --------------PFDGSGGTLAHAFFPQ---FGGDAHFDD----SESWSVASRQGVNL F---QVAAHEIGHSLGLAHSD-----------VRNALMAPFYRGYIPN-FK-LSRDDVAA VQELYGGRTDTRRF-DPPPNPLPTQGRVSRPP----------------ICNDASIDAITR LRDGTTHVFKGEEY--YRLSRT--GIDNGYPRKIHWDWRGVQGPIDAAVTWD--DSFTFI FKDDKYWKFD--GMKPVSGYPRKIREGFKGLPDKIDAAFV-----WSGNGKTYFIKGDRY WRWA---KYGIDFG---------------------------------------------- -----------------------------------------------------------Y PKQLN-VW--VNLPPRVTAAF--------------------------------------- ------------------------------------------------------------ -------------KWQNG------------------------------------------ RTYFFN-GDTYYRFNDKNFRVDD----DYPRKVSYW-WLGCADETQNQQVHDVHSVITTR PRYPDKPRTVHVSPTQDKDKDWKVIRKGNDNGGLRMQA---------------------- ------------------TRLMLAGSLFVA----FLRHQ >XP_038060416.1 matrix metalloproteinase-19-like [Patiria miniata] M-----------TGLTLLLTALLASAVTVIH------SRPVENDFDAMTYLSYFGYLKRQ ---TNDGTGMDEDEVRQGILDFQFMGNLTQTGVLDAPT-MEKMNMPRCGMPDNIGHA--- MDARRKKRFSL-GSKWRNTDLTFRIDNTTPDIPNRADVDATMVAALKVWSDVTPLTFTRV TGN-----------------TPADIVISFS----PTDRDHGDGN---------------- --------------PFDGPSGVLAHAFFPE----NGDAHFDE----GERWTINSFSGINL F---QVAAHEFGHSLGLGHSN-----------VQGALMEAFYAGYVPN-FQ-LHSDDILG IQAHYGIGSGG-----------PDVTMAPNPP------------APDIPCT-GRVDAVTT TRDQSTYIFEGSNVWKFEMGAS--RISAGFPKSISSTFVGVPDNIDAAFYYPM-YRSTFI FKGSQYWRFD--NEVMDANFPRSIT-GDWGLPGDLDAAFV-----WSGNNQVYFIKGNEY YRYN---GRAVDAN---------------------------------------------- -----------------------------------------------------------Y PRDLS-VW--NVPGNQVTAAV--------------------------------------- ------------------------------------------------------------ -------------QWTNR------------------------------------------ VTYFFTPSGGYYRYNDRNFRVEG--GRGYPAPVASD-WQGCANTIEAATPTA-------- -----------------------------DSGVSGLAP------------------SLLA ------------------MMLPVVLGTTYC--------- >XP_031552385.1 uncharacterized protein LOC116289580 [Actinia tenebrosa] --------------METLTTWLLF------------------------------------ -----------------------RFILLSVSSVLVYTH-VQVNQRSRCAVRDSMKIH--- PELAR---TPTAGFSFMSTIDSKLITRSRSQGD-KDAFNALFNEKFKCHEKYVIPVAWHV IHSTSGEGKVAKETLEKQVXVLNDAFVRTPMIFNMSSVDYTANDAWVKNCLAMSPDFMRA LSQSPSSTLNLYTCKFSVLESTIGSAAMPW--WYEEDSVYHGIVVHPDTLPGGSYAPINE G---KNTVHEVGHYFGLFHVFEGECNNMDDGVHDTPRSKPSYGCPSTDTDTCPEQPGKDP VRNYMGYTNDA-----CMTEFTTGQIERMKWA--LEKYRPSLMKMPQQPCT---IDAIFR WSNGYVYLFSGSNY--YRYNESRPGLDPGYPRSITSHWPGVPSDIDGVFRYG--NGITYF FKGKYYFRYNDTSSRVDPGFPRLINDFWRGVPSDIDDVIS------SANSYTYFFKGSQY YRFNPK-TRHVDEG------YPKAISDYWVDVPKDIEAAISWYNGGVYFFKDAQFWFFLH GNKAVGVPHGYPKPVREWWQGTMELSWYTLFRHCNGFTYFFQGNQYWRFNDNLYHVDFQY PKPITSSW--TGLPTNIDTGFMWSNKRMYFFKGTKYF--------------R--FNVTAG EL-----------DLGYPKPIVYFWKGVPH------------------------------ -------GLDAVFRYVNG------------------------------------------ ITYFFK-GSEYYRFNDTTFQIDQ----GYPRPIGNF-WKGIPDNIDSVFV---------- ---------------------W-------SNGHTYFFKGS-------LYYRFNCETKQVD ------------------QGYPKSISRWRG----MLYQP >NP_001333542.1 ZnMc domain-containing protein [Caenorhabditis elegans] --------------MTVWRRWWYLYILS--------------------------GFI--- ---------------------------------INNVM-LE------------------- -SKSRVKRYSIEGSYWGKSVITYRLKQPSQRMS-LSQQKAVFARAFATWEEHTRLWFVAV DDED---------------EQKANIDIVF------AAGDHEDGE---------------- --------------PFDGKGNILAHAFFPR---YGGDVHFDE----DELWSANKTKGVDL Y---AVAVHEIGHSLGLKHSS-----------NHLSIMAPFYKQYTGAVMH-LHQDDISA VKRLYGA---------------PVKIRKKASEHHI---------WRSELCTKPYLDAVTT LKNGTILAFRGKMF--FELKTT---RKWLLPRKINRIF-PFEGPLEAATTDR--HGNVYF FKKDTYWVMT-KHGDMMNGYPKKISQGLTDTPDGINAALY-----YHEDGKPYFFKKSYF WQYS---RYGKHKL---------------------------------------------- -----------------------------------------------------------W PRAIVSIFENQNSPPEIDAAF--------------------------------------- ------------------------------------------------------------ -------------QLNNT------------------------------------------ SSFLFH-QNKYWKVSGDPMRIEK----GFPRSLSRD-WFNC------------------- ------------------------------------------------------------ --------------------------------------L >XP_781575.3 matrix metalloproteinase-2 isoform X1 [Strongylocentrotus purpuratus] MVDISSSVSSTFTCMRATMTFISVAVVIIFHLAVNSDALPMRDAQDAKMYLMNYGYLKQS D--MANGQLTTEGDVVKALKQFQYMANIDETGTLDNDT-MRMMKMPRCGMPDMVGTG--- SHDVRKKRFTLSQLKWPYTDLTYRLDGTTPDLP-AALVNQIMALALKAWSDVSSLTFAQV AAD-----------------QPADILIDF------FEADHGDGN---------------- --------------PFDGPGAVLAHAYFPNPNPIAGDAHFDD----AETYTDGIPQGINL F---QVAAHEFGHSLGLGHST-----------IDAALMAPFYQGYVPD-FE-LHPDDVAG IQAHYGQNTNQAGG------GDDGDAAPPTPP-------------ASGDCI-SQFTATTQ TADGGFYFINDTHA--FRIGPN--GLEAGYPKTIATEFPGLPNNIDAGLFFQD-NGKTYF FKGGDYYQFS--SQTMDDGYPQAIATAFPGLPDDLDSAFV-----WTGNGRVYFTKGDQY YRFSA--GVGVDDG---------------------------------------------- -----------------------------------------------------------Y PRPLS-LW--TNLPPTLDAAM--------------------------------------- ------------------------------------------------------------ -------------QHANG------------------------------------------ FTYFFS-GDFYYRFNDDEFKVDA----GYPRDTSVG-WLGCAAAIGSGNVTVSPP----- -----------------------------GGGSTALTS--------------AGLPSLL- ------------------LVILIICSLYLADL-CVLVNL
BMGE Cleaned alignment of selected proteins >sp|P04004|VTNC_HUMAN Vitronectin OS=Homo sapiens OX=9606 GN=VTN PE=1 SV=1 LRPLLILALLAWVALADQESCKGRCTEGFKCQCDELCSYYQSCCTDYECKPQVTRGDVFPEDEYTSLTSDLAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFELLFWGRTSAGTQPQFISRDWHGVPGQVDAAMAGRIYISGMAPRPSLAKKQRFRHRNRKGYRSQRGSRRPSRAWLSLFSSEESNLGANNYDDYRMDWLVPATCEPIQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPA >NP_035837.1 vitronectin precursor [Mus musculus] LRPFFILALVAWVSLADQESCKGRCTQGFKCQCDELCTYYQSCCADYQCKPQVTRGDVFPEDDYWSPPGDL-EEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDETAVRPGYPKLIQDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPGYPRNISEGFSGIPDNVDAAFALPAHRYSGRERVYFFKGKQYWEYEFQQQPSQEECEGSSLSAVFEHFALLQRDSWENIFELLFWGRSSDGAEPQFISRNWHGVPGKVDAAMAGRIYVTGSLSHSAQAKKQKSKRRSRKRYRSRRGSRRSSRSWFSLFSSEESGLGTYNNYDYDMDWLVPATCEPIQSVYFFSGDKYYRVNLRTRRVDSVNPPYPRSIAQYWLGCPT >XP_043335857.1 vitronectin [Cervus canadensis] LRPLLMLALLAWAVVADQESCKGRCAEGFKCQCDELCSYYQSCCADFECKPQVTRGDVFPEDEYRNLAPVLAEEETCSGKPFDAFTDLKNGSLFAFRGLYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRVNCEGKTYLFKGSLYWRFEDGVLEPDFPRNISDGFKGIPDDVDAALALPAHSYNGRERVYFFKGNHYWEYVFQQQPSQEECEGGSQPAAFKHFALMQRDSWEDIFRLLFWGGPSGGAQPRLISRDWLGLPRRLDAAMAGHIYVSGSAPSFPQAKMTKSARRHRKRYRSLRNPYRRSRSWLSWFSSEELGLGANNYDNYEMDWLVPATCEPIQSVYFFSEDKYYRVNLRTRRVDTVIPPYPRSIAQYWLGCPV >KAF4012137.1 hypothetical protein G4228_003124 [Cervus hanglu yarkandensis] LRPLLMLALLAWAVVADQESCKGRCAEGFKCQCDELCSYYQSCCADFECKPQVTRGDVFPEDEYRNLAPVLAEEETCSGKPFDAFTDLKNGSLFAFRGLYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRVNCEGKTYLFKGSLYWRFEDGVLEADFPRNISDGFKGIPDDVDAALALPAHNYNGRERVYFFKGNHYWEYVFQQQPSQEECEGGSQPAAFKHFALMQRDSWEDIFRLLFWGGPSGGAQPRLISRDWLGLPRRLDAAMAGHIYVSGSAPSFPQAKMTKSARRHRKRYRSLRNPYRRSRSWLSWFSSEELGLGANNYDNYEMDWLVPATCEPIQSVYFFSEDKYYRVNLRTRRVDTVIPPYPRSIAQYWLGCPV >OWK14767.1 VTN [Cervus elaphus hippelaphus] LRPLLMLALLAWAVVADQESCKGRCAEGFKCQCDELCSYYQSCCADFECKPQVTRGDVFPEDEYRNLAPVLAEEETCSGKPFDAFTDLKNGSLFAFRGLYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRVNCEGKTYLFKGSLYWRFEDGVLEPDFPRNISDGFKGIPDDVDAALALPAHNYNSRERVYFFKGNHYWEYVFQQQPSQEECEGGSQPAAFKHFALMQRDSWEDIFRLLFWGGPSGGAQPRLISRDWLGLPRRLDAAMAGHIYVSGSAPSFPQAKMTKSARRHRKRYRSLRNPYRRSRSWLSWFSSEELGLGANNYDNYEMDWLVPATCEPIQSVYFFSEDKYYRVNLRTRRVDTVIPPYPRSIAQYWLGCPV >KAB0358735.1 hypothetical protein FD754_002891 [Muntiacus muntjak] LRPLLMLALLAWAVVADQESCKGRCAEGFKCQCDELCSYYQSCCADFECKPQVTRGDVFPEDEYRTLAPVLAEEETCSGKPFDAFTDLKNGSLFAFRGLYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRVNCQGKTYLFKGSLYWRFEDGVLEPDFPRNISDGFKGIPDDVNAALALPAHNYNGRERVYFFKGNHYWEYVFQQQPSQEECEGGSQPAAFKHFALMQRDSWEDIFRLLFWGGPSGGAQPRLISRDWLGLPRRLDAAMAGHIYVSGSAPSFPQAKMTKSARRHRKRYRSLRSPYRRSRSWLSWFSSEELGLGANNYDNYEMDWLVPATCEPIQSVYFFSEDKYYRVNLRTRRVDTVIPPYPRSIAQYWLGCPV >KAB0367524.1 hypothetical protein FD755_020848 [Muntiacus reevesi] LRPLLMLALLAWAVVADQESCKGRCAEGFKCQCDELCSYYQSCCADFECKPQVTRGDVFPEDEYRTLAPVLAEEETCSGKPFDAFTDLKNGSLFAFRGLYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRVNCQGKTYLFKGSLYWRFEDGVLEPDFPRNISDGFKGIPDDVDAALALPAHNYNGRERVYFFKGNHYWEYVFQQQPSQEECEGGSQPAAFKHFALMQRDSWEDIFRLLFWGGPSGGAQPRLISRDWLGLPRRLDAAMAGHIYVSGSAPSFPQAKMTKSARRHRKRYRSLRSPYRRSRSWLSWFSSEELGLGANNYDNYEMDWLVPATCEPIQSVYFFSEDKYYRVNLRTRRVDTVIPPYPRSIAQYWLGCPV >NP_001184010.1 vitronectin L homeolog precursor [Xenopus laevis] LFPALLLGAVR-AAHAAEESCAGRCFSGFKCQCDIICVHFESCCIDYLCKPKEQRGDVFPEDEYN-------QDELCSGQPFDAFTNIKNGSIYAFRGKYFYELDDKSALEGYPKLIKDVWGIDGPVDAAFTRMNCQGKTYLFKGKEYWRFSNGVLESDYPRNISEGFHDIPDNIDAAFALPANNHNDREKVYFFKGNKYWQYEFQNQPSRKDCQDSAQSELFTYYVTLQKDSWEDFFSFLFGPSMKRSTGPWYINKDWKGVPNNVDAVLPSRIYVPKQT------------RRSRRRKSRRRNKSGGMRSWSDFSFDPLDGLFDYDDEQSDPDWLPPERCQPTQNVYFFKNDKYYRVNLRTKRVDYVYPPYPRSIAQYWLGCKK >XP_015807112.1 PREDICTED: vitronectin-like [Nothobranchius furzeri] LFIILLLALVA-DGLTEDESCLVRCENGFKCQCDSMCKYYSSCCKDYLCG-MMTRGDTFAEDDYDPLVPDF-DAEVCSGRPFDAFMQLKNGSIYAFRGKYFFELDQKSVLTGYPKLIKDVWGIEGPIDAAFTRINCQGKTYIFKGNKYWRFDNNELDDDYPRDISVGFDKIPDHVDAAFALPAHSHHGKEKVYFFKNDQYYVYEFLHQPSHEECSERSPSALFRRYTDLYYNNYERFFHELFSDLPQHH-KHHFINKDWKGLKSPVDAAMSGRIYITTGR--------SMPRRYDYQ-PDQQGGEDRLGRDDRRWDQDDQDRRWDRYNQNNRGNYDSRNDDMPIQSVYFFKADKYYRVDLRTKRVDPAMPPYPRSIAKYWLGCSD >XP_021337086.1 vitronectin isoform X1 [Danio rerio] --FLLLLVLLS-FADAAEESCIERCENGFSCQCDSMCTYYKSCCTDYLCRIKA-RGDTFPEDDYDLEISSM-DAEVCSGRPFDAFMQLKNGSIYAFRGEYFFELDEKSVLPGYPKLIEDIWGIKGPIDAAFTRINCQGKTYIFKGNKYWRFDDGVLDDDFPRDIAVGFEKIPDHLDAAFATPAHSHHGKEKVYFFKGDQYYHYEFKHQPSHEECSLRSPSMLFRRYTDIYYDRWTEHFNQLFGGAQSHH-GHHFINRDWIGIKSPVDAVLVGRLYVTPRW--------QNRRRQDRNRWDQQQGSQRFGQD--RWR--DQDRRRDYYDRQNDYDYDYRYKSQPLQSVYFFKGDKYYRVNLQTKRVDYANPPYPRPIGKYWLGCKD >XP_030260427.1 vitronectin-like [Sparus aurata] LWAILLLALLA-QALAEDKSCMGRCENGFKCQCDSMCKYYKSCCSDYTCG-MTTRGDTYADDDDEQAISDF-DAVVCSGRPFDSFMQLKNGSIYAFRGDYFFELDQKSVLPGYPKLIKDVWGIRGPIDAAFTRVNCQGKTYIFKGNQYWRFDNGVLDDDYPRDISVGFDKIPDHVDAAFALPAPGHNGKEKVYFFKGEQYYTYEFLHQPSHEECSESSPSTLFRRYTDIYYNNYERSLSELFSDLPQHH-KHHFIEKDWKGLKAPLDAVMTGRMYVPPLR--------STPRRNDYR-YDQQYGEERLGRDDRRWDQDDQDRRRDGHRQNNRGNYDSRSYEQPIQTVYFFKGDKYYRVDLRTKRVDPGSPPYPRSIAKYWLGCSD >XP_023818375.1 vitronectin [Oryzias latipes] LALLSLLLVVE-STSAAEESCVGLCG-SFKCQCDSMCVYYSSCCGDFICAKKVTRGDVFVENTTA-------DAAPCSGRPFDAFLQLKNGSIYAFRGDYFFELDDDSILPGYPKLIQDAWGISGPISAAFTRINCQGKSYIFKGSRYWRYNGNVLDEGFPRDISEGFQDIPNDIDAAFTVPAPNHRGKEKAYFFKGDKYYKYEFKHQPSHEECTKASPSVLFTQYTDLFCDTAEDLFTGLFGSSFDSQRNPRFISGDWHGIRPPVDAAVVGRVHLSVKPTA------SPPRRGSSRR------RRRLSHRFGDLWNDDD-----FAFSMDESDFTDQSTQIPVQNVYFFKKDKYYRVGLRSKRVDFANPPYPRSIAKYWLGCKE >NP_062029.2 vitronectin precursor [Rattus norvegicus] LRPFFILALLALVSLADQESCKGRCTQGFKCQCDELCTYYQSCCVDYQCKPQVTRGDVFPEDEYWSLHFNL-EEELCSGKPFDAFTDLKNGSLFAFRGEYCYELDETAVRPGYPKLIQDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISEGFSGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYEFQQQPSQEECEGSSLSAVFEHFALLQRDSWENIFELLFWGRSSDGAGPQFISRDWHGVPGKVDAAMAGRIYITGSTFRSVQAKKQKSGRRSRKRYRSRRGSRRPSRSWFSLLSSEESGLGTYNY-DYDMNWRIPATCEPIQSVYFFSGDKYYRVNLRTRRVDSVNPPYPRSIAQYWLGCPT >NP_990392.1 vitronectin precursor [Gallus gallus] LLPVLVLALLA-LTRAAEDSCEGRCDEGFKCQCDTLCNYYQSCCSDYVCKAKVTRGDVFPEDDYLPTEPHS-PEELCSRKPFNAFTDLKNGSIYAFRGKYFYELDKSSVRPGYPKLISDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFDDGALDPGYPRDISEGFEGIPNDIDAAFALPAHSYHGNERVYFFKGKYYWSYDFAHQPTQAECEKSSPSTVFNHYAFMNRDSWEDIFLSLFGSRMVGA-SQRLISRDWRGVPNQLDAAMAGRIYVSSRQPR------RRSSRRHRKRYRNHRT---LNLGW-SWLNSDSES------TDTESDWLSGSQCETLQSVYFFVGDKYYRVNLRTKRVDLVQPPYPRSIAQYWLDCPQ >NP_999269.1 vitronectin precursor [Sus scrofa] LRPLLMLALLAWVALADQESCKGRCTDGFKCQCDELCSYYQSCCTDYECKPQVTRGDVFPDDEYR---PVL-EEELCSGKPFDAFTNLKNGSVFAFRGLYCYELDEKAVRPGYPKLIQDVWGIKGPIDAAFTRINCQGKTYLFKGSQYWRFDDGVLDPNYPREISEGFKGIPDDVDAALALPAHSYSGRERVYFFKGKQYWEYVFQQQPSREECEGSSPSDVFAHFALMQRDSWEDIFRLLFWSHSFGGAEPRVISQDWLGLPEQVDAAMAGQIYISGSALKPSQPKMTKSARRSGKRYRSRRGSHRQSRSWLPWFSSEETGPGGYNYDDYKMDWLVPATCEPIQSVYFFSGEEYYRVNLRTQRVDTVTPPYPRSIAQYWLGCPV >XP_854040.1 vitronectin [Canis lupus familiaris] PRPLLVLALLAWVVLADQESCKGRCTEGFKCQCDELCSYYQSCCEDYECKPQVTRGDVFPEDEYGTLSPGLAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISEGFKGIPDNVDAAFALPARSYSGRERVYFFKGRQYWEYEFQQQPSQEECEGSSLSTVFEHFALLQRDSWETFFELLFWNRPSGGAEPGFISQDWPGLPRQVDAAMAGRIYISGSAPR-SWVKKLNPKRRNRKRYRSRRNSQRQSRSWLSWFSSEESGLDTYNYDDYNMDWLVPATCEPIQSVYFFSEDKYYRVNLRTRRVDTVSPPYPRSIAQYWLGCSA >NP_001030222.1 vitronectin precursor [Bos taurus] LRPLLMLALLAWVVVADQESCKGRCTEGFKCQCDELCSYYQSCCADFECKPQVTRGDVFPEDEYGTLAPVLAEEETCSGKPFDAFTDLKNGSLFAFRGLYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRVNCQGKTYLFKGSQYWRFQDGVLEPDFPRNISDGFGGIPDDVDAALALPAHNFNGRERVYFFKGNHYWEYVFQQQPSQEDCEGSSLPAAFKHFALMQRDSWVDIFRLLFWGGSYGGAQPQLISRNWFGLPGRLDAAMAGHIYVSGSAPSFPRAKMTKSARRHRKRYRSLRSPYRRSRSFLSWLSSEELGLGANNYDSFEMDWLVPATCEPIQSVYFFSEDKYYRVNLRTRRVDAVIPPYPRSIAQYWLGCPV >XP_001146856.1 vitronectin [Pan troglodytes] LRPLLILALLAWVALADQESCKGRCTEGFKCQCDELCSYYQSCCTDYECKPQVTRGDVFPEDEYTSLTSDLAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFELLFWGRTSAGTQPQFISRDWHGVPGQVDAAMAGRIYISGMAPRPSLAKKQKFRHRNRKGYRSQRGSRRPSRAWLSLFSSEESNLGANNYDDYRMDWLVPATCEPIQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPA >NP_001075761.1 vitronectin precursor [Oryctolagus cuniculus] LRPIFTLALLLWVVLADQESCKDRCTEGFKCQCDELCSYYQSCCADYECKPQVTRGDVFPEDEYGTLSPDLAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDETAVRPGYPKLIQDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGILDPDYPRNISEGFSGIPDNVDAAFALPAHSYSGRERVYFFKGDKYWEYQFQQQPSQEECEGSSLSAVFEHFAMLHRDSWEDIFKLLFWGRPSGGAQPQFISRDWHGVPGKVDAAMAGRIYISGLTPS-PSAKKQKSRRRSRKRYRSRYGSRRLSRSSRLWFSSEEVSLGPYNYEDYETSWLKPATSEPIQSVYFFSGDKYYRVNLRTQRVDTVNPPYPRSIAQYWLGCPA >NP_001127063.1 vitronectin precursor [Pongo abelii] LRPLLILALLAWVALADQESCKGRCTEGFKCQCDELCSYYQSCCTDYECKPQVTRGDVFPEDEYSSLTPDFAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQEECEGSSLSAVFEHFAMIQRDSWEDIFELLFWGRTSAGTQPQFISRDWHGVPGQVDAAMAGRIYISGMAPRPALAKKQKFRRRNRKGYRSHRGSRRPSHAWLSLFSSEDSNLGANNYDDYRMDWLVPATCEPIQSVFFFSGDKYYRVNLRTRRVDAVDPPYPRSIAQYWLGCPA >XP_003211803.2 vitronectin [Meleagris gallopavo] LLLVLVLALLA-PTRAAEDSCEGRCDEGFKCQCDNLCNYYQSCCSDYVCKAKVTRGDVFPEDDYLPTEPHT-PEKLCSRKPFNAFTDLKNGSLYAFRGKYFYELDESSVRPGYPKLISDVWGIEGPIDAAFTRINCQGKTYLFKGNKYWRFDDGALEPGYPRDISEGFEGIPNDIDAAFALPAHSYHGNERVYFFKGKYYWSYDFAHQPTQAECDKSSPSTVFNHYAFMNRDSWEDIFFSLFGSRMVGA-SPRLISRDWRGVPNQLDAAMAGRIYVSSRQPR------RRNSRRHRKRYRNHRT---LNLGW-GWLNNDSES------TDTESDWLSGSQCETLQSVYFFVGDKYYRVNLRTKRVDLVQPRYPRSIAQYWLDCPQ >XP_005693309.1 PREDICTED: vitronectin [Capra hircus] LRPLLMLALLVWVVVADQESCKGRCTEGFKCQCDELCSYYQSCCADFECKPQVTRGDVFPEDEYGTLAPVLAEEETCSGKPFDAFTDLKNGSLFAFRGLYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRFNCQGKTYLFKGSQYWRFEDGVLEPDFPRNISDGFKGIPDDVDAALALPAHSYNGRERVYFFKGNHYWEYVFQQQPSREECEGSSQPAAFKHFALMQRDSWEDIFRLLFWGGSFGGAQPQLISRDWFGLPGKLDAAMAGHIYISGSAPSSPRAKMTKSARRHRKRYRSLRSPYRRFRSWLSWFSSEELGLGADNYDNYEMDWLVPATCEPIQSVYFFSEDKYYRVNLRTRRVDSVIPPYPRSIAQYWLGCPV >XP_003812709.1 vitronectin [Pan paniscus] LRPLLILALLAWVALADQDSCKGRCTEGFKCQCDELCSYYQSCCTDYECKPQVTRGDVFPEDEYTSLTSDLAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFELLFWGRTSAGTQPQFISRDWHGVPGQVDAAMAGRIYISGMAPRPSLAKKQKFRHRNRKGYRSQRGSRRPSRAWLSLFSSEESNLGANNYDDYRMDWLVPATCEPIQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPA >XP_003996546.1 vitronectin [Felis catus] PRPLLILALLAWVVLADRESCKGRCTEGFKCQCDELCSYYQSCCEDYECKPQVTRGDVFPEDEYGSQGPDLVVEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEEAVSPGYPKLIQDVWGIEGPIDAAFTRINCQGKTYLFQGHQYWRFEDGVLDPDYPRNISEGFKGIPDNVDAALALPAHSYSGRERAYFFKGRQYWEYEFQQQPSQEECEGSSLSAVFEHFALLQRDSWETLFEFLFGNRFSGGAQPRLISRDWPGVPRQVDAAMAGRIYISGSAPQ-SWAEKQKSRRRNRKRYRSRRNPHRQSRSWLSWLSSEEDSLGIYNFRDYDMDWLVPATCEPIQSVYFFSGDKYYRVNLRTRQVDTVSPPYPRSIAQYWLGCPA >XP_027831040.1 vitronectin [Ovis aries] LRPLLMLALLAWVVVADQESCKGRCTEGFKCQCDELCSYYQSCCADFECKPQVTRGDVFPEDEYGTLAPVLAEEETCSGKPFDAFTDLKNGSLFAFRGLYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRFNCQGKTYLFKGSQYWRFEDGVLEPEFPRNISDGFKGIPDDVDAALALPAHSYNGRERVYFFKGNHYWEYVFQQQPSQEECEGSSQPAAFKHFALMQRDSWEDIFRLLFWGGSFGGAQPQLISRDWFGLPGKLDAAMAGHIYISGSAPSSPRAKMTKSARRHRKRYRSLRSPYRRFRSWLSWFSSEELGLGADNYDNYEMDWLVPATCEPIQSVYFFSEDKYYRVNLRTRRVDSVIPPYPRSIAQYWLGCPV >XP_004042098.1 vitronectin [Gorilla gorilla gorilla] LRPLLILALLAWVALADQESCKGRCTEGFKCQCDELCSYYQSCCTDYECKPQVTRGDVFPEDEYTSLTSDLAEEELCSGKPFDAFTDLKNGSLFAFRGQYCYELDEKAVRPGYPKLIRDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFEDGVLDPDYPRNISDGFDGIPDNVDAALALPAHSYSGRERVYFFKGKQYWEYQFQHQPSQEECEGSSLSAVFEHFAMMQRDSWEDIFELLFWGRTSAGTQPQFISRDWHGVPGQVDAAMAGHIYISGMAPRPSLAKKQKFRHRNRKGYRSQRGSRRPSRAWLSLFSSEESNLGANNYDDYRMDWLVPATCEPVQSVFFFSGDKYYRVNLRTRRVDTVDPPYPRSIAQYWLGCPA >XP_013222293.1 vitronectin [Columba livia] LFAVLALALLA-AARAAEDSCEGHCDDGFKCQCDTLCVYYQSCCSDYACKAKVTRGDVFPEDDYLPTTPLP-PEELCSGKPFNAFTDLKNGSLYAFRGKYFYELDETSVRPGYPKLISDVWGIEGPIDAAFTRINCQGKTYLFKGSQYWRFDDGALDPGYPRNISDGFEGIPNSIDAAFALPAHSYHGNERVYFFKDKYYWSYDFAQQPTQADCEKSSPSTVFNHYAFMNRDSWEDVFHILFGGRITGA-SPRYISRDWQGVPGRQD--------LRGHPPAP-----------------------------------QEEV------------------SPPAQEVQ--------------------EPP----VTEFFLGLAG >XP_025070384.1 vitronectin [Alligator sinensis] LLPAVLLGLFG-VALAAEESCAGRCDVAFKCQCDPLCVYYQSCCSDYVCKTKVTRGDVFPEDDYS---PST-QEEACSGKTFDAFTDLKNGSIFAFRGKYFYELNETSVMPGYPKLIRDVWGMDGPIDAAFTRINCQGKTYIFKGSQYWRFDDGALDPGYPLNISEGFEGIPDDLDAAFALPAENYADNERVYFFKGRHYWSYEFAQQPTWEECEQDSQSAAFWHFAFLVGTDWDDIFDMPFGLSSSKCR------GAWGGEAWECELS--------------------------------------PSRRW-PWLQDDSES------WELDSDWVYMGTCQPVQSIYFFVGDKYYRVNLKTMRVDWVHPRYPRPVAQYWLGCPR >XP_020740434.1 vitronectin isoform X1 [Odocoileus virginianus texanus] RRPLLMLALLAWAAVADQESCKGRCAEGFKCQCDELCSYYQSCCADFECKPQVTRGDVFPEDEYRTLAPVLAEEETCSGKPFDAFTDLKNGSLFAFRGLYCYELDEKAVRPGYPKLIQDVWGIEGPIDAAFTRVNCQGKTYLFKGSLYWRFEDGVLEPDFPRNIADGFKGIPDDVDAALALPAHSYNGRERVYFFKGNHYWEYVFQQQPSQEECEGSSQPAAFKHFALMQRDSWEDIFRLLFWGGPSGGAQPRLISRDWLGLPRRLDAAMAGHIYVSGSAPSFPQAKMTKSARRHRKRYRSLRSPYRRSRSWLSWFSSEELGLGANNYDNYEMDWLVPATCEPIQSVYFFSEDKYYRVNLRTRRVDTVIPPYPRSIAQYWLGCPV >XP_040194287.1 vitronectin [Rana temporaria] LLPAILLGAID-SALPAEESCVGRCLEGFKCQCDDLCIYYGSCCSDFVCVKKETRGDVFPEDEFD-------PEELCSGKPFDAFTNLKNGSIYAFRGEYFYELDDKKALDGYPKRIKDVWGIEGPIDAAITRMNCEGKTYIFKGTQYWRFSDGVLDSDYPRDIDVGFKNIPNDIDAAFALPANNYQGKERAYFFKGRQYWQYEFTQQPTREECLGSPPSEIFTRYAAMQDDSWEDIFSLLFGKLFTGNSEPKSISRDWRGVPYGVNAVLPSRIYIPQQK--------QPALRRSKRRKSSRRKRRRPSKPYYDFSDL-----YDFDDYEDDPDWLPPESCQPVQSVFFFKDDKYYRVNLQTKRVDYTYPPYPRSIAEYWLGCKK >NP_001189002.1 matrix metalloproteinase 1, isoform H [Drosophila melanogaster] QSSVFILDAET-MKLMSLPRCGVRDRVGTRVDVDAEIGRAFAVWSEDLTFTRKTPVHIEVESEHGVAAHEFLDDSICKDSKVDTLFNSAQGETYAFKGDKYYKLTTDSVEEGYPQLISKGWGLPGNIDAAFTYK--NGKTYFFKGTQYWRYQGRQMDGVYPKEISEGFTGIPDHLDAAMV-----WGGNGKIYFFKGSKFWRFDPAKRPPVKAS------------------------------------YPKPIS-NWEGVPNNLDAAL-------------------------------------------KYTNG---------------------------YTYFFKGDKYYRFHDARFAVDSATPPFPRPTAHWWFGCKN >KAG6797835.1 Matrix metalloproteinase-14 [Apis mellifera caucasica] ---------------MTLPRCGVKDKVGPQHKVDAELNKAFKVWSEYLVFVQKKQVHIEEKGEHGVAAHEF-DSELCTNSKVDTMFNSAEGHMYVFKGDRYWRLTSDGVAIGYPKLISHSWGLPGNIDAAFTYK--NGKTYFFKGSKYWRYVGKKMDGDYPKEISEGFTGIPDNIDTVTV-----WTGNGKLYFYKGSKFWRFDPSQKPPVKNT------------------------------------YPKLIS-NWEGLPDNLDASI-------------------------------------------VYRG----------------------------YTYFFKGDAYYRFNDRTFSVDIADPAFPRSTAYWWFGCRS >XP_039256216.1 matrix metalloproteinase-24-like [Styela clava] LTFVLLLDHIT-LEKMDSPRCGNRDVVGSRRDTENAINKAFKVWEAELTFRQVRKADIEAEKAHGVAAHEFPPVGACN-GRFDAITMVRNGTTYAFKGDKFWKLNDQGMEPGYPKSTKKIWGLSGKVDASLSF---GAYTDLFQGDVIHRYINGIPMHGYPKRISEVYKGIPSKLDTAFV-----WSGNGKVYFVKGDKYWRYNPS-LRKSDNG------------------------------------YPRPLS-VWKGLPERLDAAL-------------------------------------------KWKD----------------------------RTYFFKNGYYWRFDDERVEVAQSKTPYPRRSDAWWLGCTD >CAE1318974.1 MMP14 [Sepia pharaonis] RLNRIRPNELF-SARLGRTNCSLPAWVERRLKVEREIARAFKVWSEVLTFTQKDPVDIEARNHHGVAAHEI----ICNDASIDAITRLRDGTTHVFKGEEYYRLSRTGIDNGYPRKIHWDWGVQGPIDAAVTWD--DSFTFIFKDDKYWKFDGMKPVSGYPRKIREGFKGLPDKIDAAFV-----WSGNGKTYFIKGDRYWRWA---KYGIDFG------------------------------------YPKQLN-VWVNLPPRVTAAF-------------------------------------------KWQNG---------------------------RTYFFNGDTYYRFNDKNFRVDD---DYPRKVSYWWLGCAD >XP_038060416.1 matrix metalloproteinase-19-like [Patiria miniata] LTALLALDAPT-MEKMNMPRCGMPDNIGHRADVDATMVAALKVWSDVLTFTRVTPADIVTDRDHGVAAHEFAPDIPCT-GRVDAVTTTRDQSTYIFEGSNVFEMGASRISAGFPKSISSTFGVPDNIDAAFYYPM-YRSTFIFKGSQYWRFDNEVMDANFPRSIT-GDWGLPGDLDAAFV-----WSGNNQVYFIKGNEYYRYN---GRAVDAN------------------------------------YPRDLS-VWNVPGNQVTAAV-------------------------------------------QWTNR---------------------------VTYFFTSGGYYRYNDRNFRVEG-GRGYPAPVASDWQGCAN >XP_031552385.1 uncharacterized protein LOC116289580 [Actinia tenebrosa] TTWLLFLVYTH-VQVNQRSRCAVRDSMKIKDAFNALFNEKFKCHEKYPVAWHVILNDAFSSVDYTNTVHEVMPQQPCT---IDAIFRWSNGYVYLFSGSNYYRYNESGLDPGYPRSITSHWGVPSDIDGVFRYG--NGITYFFKGKYYFRYNSSRVDPGFPRLINDFWRGVPSDIDDVIS------SANSYTYFFKGSQYYRFNPK-TRHVDEG---YPKAISDYWVDVPKDSWYTLFRHCFTYFFQGNQYPKPITSSWTGLPTNIDTGFMKRMYFFKGTKYF--------------RFNVTAG----GLDVFRYVNG---------------------------ITYFFKGSEYYRFNDTTFQIDQ---GYPRPIGNFWKGIPD >NP_001333542.1 ZnMc domain-containing protein [Caenorhabditis elegans] RRWWYLINNVM-LE---------------LSQQKAVFARAFATWEEHLWFVAVDKANIDAAGDHEVAVHEIWRSELCTKPYLDAVTTLKNGTILAFRGKMFFELKTT-RKWLLPRKINRIFPFEGPLEAATTDR--HGNVYFFKKDTYWVMTHGDMMNGYPKKISQGLTDTPDGINAALY-----YHEDGKPYFFKKSYFWQYS---RYGKHKL------------------------------------WPRAIVSIFQNSPPEIDAAF-------------------------------------------QLNNT---------------------------SSFLFHQNKYWKVSGDPMRIEK---GFPRSLSRDWFNC-- >XP_781575.3 matrix metalloproteinase-2 isoform X1 [Strongylocentrotus purpuratus] MTFISVLDNDT-MRMMKMPRCGMPDMVGTAALVNQIMALALKAWSDVLTFAQVAPADILFEADHGVAAHEF-ASGDCI-SQFTATTQTADGGFYFINDTHAFRIGPNGLEAGYPKTIATEFGLPNNIDAGLFFQD-NGKTYFFKGGDYYQFSSQTMDDGYPQAIATAFPGLPDDLDSAFV-----WTGNGRVYFTKGDQYYRFSA--GVGVDDG------------------------------------YPRPLS-LWTNLPPTLDAAM-------------------------------------------QHANG---------------------------FTYFFSGDFYYRFNDDEFKVDA---GYPRDTSVGWLGCAA
PhyML tree of selected proteins (XP_039256216_1_matrix_metalloproteinase_24_like__Styela_clava_:0.95493539,CAE1318974_1_MMP14__Sepia_pharaonis_:1.08984555,((XP_038060416_1_matrix_metalloproteinase_19_like__Patiria_miniata_:0.76923969,XP_781575_3_matrix_metalloproteinase_2_isoform_X1__Strongylocentrotus_purpuratus_:0.81406835):0.33566021,((NP_001189002_1_matrix_metalloproteinase_1__isoform_H__Drosophila_melanogaster_:0.22857206,KAG6797835_1_Matrix_metalloproteinase_14__Apis_mellifera_caucasica_:0.44644448):0.53756449,(XP_031552385_1_uncharacterized_protein_LOC116289580__Actinia_tenebrosa_:1.63000074,(NP_001333542_1_ZnMc_domain_containing_protein__Caenorhabditis_elegans_:2.30819729,((XP_025070384_1_vitronectin__Alligator_sinensis_:0.44778008,(XP_013222293_1_vitronectin__Columba_livia_:0.21215256,(XP_003211803_2_vitronectin__Meleagris_gallopavo_:0.04315347,NP_990392_1_vitronectin_precursor__Gallus_gallus_:0.01069181):0.10136814):0.11427542):0.04514047,(((XP_023818375_1_vitronectin__Oryzias_latipes_:0.54681801,(XP_021337086_1_vitronectin_isoform_X1__Danio_rerio_:0.21041473,(XP_015807112_1_PREDICTED__vitronectin_like__Nothobranchius_furzeri_:0.130278,XP_030260427_1_vitronectin_like__Sparus_aurata_:0.14540943):0.21010314):0.21507359):0.30267016,(NP_001184010_1_vitronectin_L_homeolog_precursor__Xenopus_laevis_:0.31540773,XP_040194287_1_vitronectin__Rana_temporaria_:0.26682852):0.21741671):0.11989665,(((NP_999269_1_vitronectin_precursor__Sus_scrofa_:0.10729059,((NP_001030222_1_vitronectin_precursor__Bos_taurus_:0.04170144,(XP_027831040_1_vitronectin__Ovis_aries_:0.0028601,XP_005693309_1_PREDICTED__vitronectin__Capra_hircus_:0.00579135):0.01867572):0.01281498,(XP_020740434_1_vitronectin_isoform_X1__Odocoileus_virginianus_texanus_:0.01160035,(KAB0367524_1_hypothetical_protein_FD755_020848__Muntiacus_reevesi_:0.00000001,((XP_043335857_1_vitronectin__Cervus_canadensis_:0.00289593,(OWK14767_1_VTN__Cervus_elaphus_hippelaphus_:0.00289413,KAF4012137_1_hypothetical_protein_G4228_003124__Cervus_hanglu_yarkandensis_:0.00289393):0.00000001):0.0087263,KAB0358735_1_hypothetical_protein_FD754_002891__Muntiacus_muntjak_:0.00288818):0.00000001):0.00580748):0.01983987):0.11592694):0.06314762,(XP_003996546_1_vitronectin__Felis_catus_:0.08328578,XP_854040_1_vitronectin__Canis_lupus_familiaris_:0.0655791):0.03690526):0.01284309,((NP_001127063_1_vitronectin_precursor__Pongo_abelii_:0.01940538,(XP_004042098_1_vitronectin__Gorilla_gorilla_gorilla_:0.00567386,(XP_001146856_1_vitronectin__Pan_troglodytes_:0.00000001,(sp_P04004_VTNC_HUMAN_Vitronectin_OS_Homo_sapiens_OX_9606_GN_VTN_PE_1_SV_1:0.00283426,XP_003812709_1_vitronectin__Pan_paniscus_:0.00283278):0.00000001):0.00000001):0.00960203):0.07640747,(NP_001075761_1_vitronectin_precursor__Oryctolagus_cuniculus_:0.10826793,(NP_062029_2_vitronectin_precursor__Rattus_norvegicus_:0.04255827,NP_035837_1_vitronectin_precursor__Mus_musculus_:0.04241543):0.06133092):0.02371691):0.00469426):0.24586862):0.04946412):1.13889385):0.38638568):0.24002651):0.10239293):0.19590446);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)