PB0095
DATABASE


Click here to access PB0095 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0095 P22891 Vitamin K-dependent protein Z PROZ protein Z, vitamin K dependent plasma glycoprotein, PZ Homo_sapiens Appears to assist hemostasis by binding thrombin and promoting its association with phospholipid vesicles. Inhibits activity of the coagulation protease factor Xa in the presence of SERPINA10, calcium and phospholipids.

DomainsGene Ontology
PF00008 (EGF)
PF00089 (Trypsin)
PF00594 (Gla)
GO:0004252 (enables) serine-type endopeptidase activity
GO:0005509 (enables) calcium ion binding
GO:0005515 (enables) protein binding
GO:0006508 (involved in) proteolysis
GO:0007596 (involved in) blood coagulation
GO:0007599 (involved in) hemostasis
GO:0005615 (is active in) extracellular space
GO:0005576 (located in) extracellular region
GO:0005788 (located in) endoplasmic reticulum lumen
GO:0005796 (located in) Golgi lumen
GO:0070062 (located in) extracellular exosome

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences


Created by Puigbo and Nakamura @ University of Turku (2022)