Click here to access PB0091 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0091 Q07092 Collagen alpha-1(XVI) chain COL16A1 447AA, FP1572, collagen type XVI alpha 1 chain Homo_sapiens Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology.

DomainsGene Ontology
PF01391 (6_Collagen)
GO:0005178 (enables) integrin binding
GO:0005201 (enables) extracellular matrix structural constituent
GO:0030020 (enables) extracellular matrix structural constituent conferring tensile strength
GO:0007155 (involved in) cell adhesion
GO:0007229 (involved in) integrin-mediated signaling pathway
GO:0007565 (involved in) female pregnancy
GO:0030198 (involved in) extracellular matrix organization
GO:0033622 (involved in) integrin activation
GO:0033627 (involved in) cell adhesion mediated by integrin
GO:0051894 (involved in) positive regulation of focal adhesion assembly
GO:0071230 (involved in) cellular response to amino acid stimulus
GO:0005615 (is active in) extracellular space
GO:0031012 (is active in) extracellular matrix
GO:0005576 (located in) extracellular region
GO:0005788 (located in) endoplasmic reticulum lumen
GO:0005581 (part of) collagen trimer
GO:0005588 (part of) collagen type V trimer
GO:0005597 (part of) collagen type XVI trimer
GO:0062023 (part of) collagen-containing extracellular matrix

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)