Click here to access PB0090 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0090 P12111 Collagen alpha-3(VI) chain COL6A3 BTHLM1, DYT27, UCMD1, collagen type VI alpha 3 chain Homo_sapiens Collagen VI acts as a cell-binding protein.

DomainsGene Ontology
PF00014 (Kunitz_BPTI)
PF00092 (11_VWA)
PF01391 (Collagen)
GO:0004867 (enables) serine-type endopeptidase inhibitor activity
GO:0030020 (enables) extracellular matrix structural constituent conferring tensile strength
GO:0030414 (enables) peptidase inhibitor activity
GO:0007155 (involved in) cell adhesion
GO:0007517 (involved in) muscle organ development
GO:0010466 (involved in) negative regulation of peptidase activity
GO:0010951 (involved in) negative regulation of endopeptidase activity
GO:0005615 (is active in) extracellular space
GO:0062023 (is active in) collagen-containing extracellular matrix
GO:0005576 (located in) extracellular region
GO:0005788 (located in) endoplasmic reticulum lumen
GO:0031012 (located in) extracellular matrix
GO:0042383 (located in) sarcolemma
GO:0070062 (located in) extracellular exosome
GO:1903561 (located in) extracellular vesicle
GO:0005581 (part of) collagen trimer
GO:0005589 (part of) collagen type VI trimer

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)