Click here to access PB0078 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0078 P10915 Hyaluronan and proteoglycan link protein 1 HAPLN1 CRT1, CRTL1 Homo_sapiens Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.

DomainsGene Ontology
PF00193 (2_Xlink)
PF07686 (V-set)
GO:0005540 (enables) hyaluronic acid binding
GO:0030021 (enables) extracellular matrix structural constituent conferring compression resistance
GO:0001501 (involved in) skeletal system development
GO:0007155 (involved in) cell adhesion
GO:0007417 (involved in) central nervous system development
GO:0031012 (is active in) extracellular matrix
GO:0005576 (located in) extracellular region
GO:0045202 (located in) synapse
GO:0062023 (located in) collagen-containing extracellular matrix

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)