Click here to access PB0071 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0071 Q9UMD9 Collagen alpha-1(XVII) chain COL17A1 BA16H23.2, BP180, BPA-2, BPAG2, ERED, LAD-1, collagen type XVII alpha 1 chain Homo_sapiens The 120 kDa linear IgA disease antigen is an anchoring filament component involved in dermal-epidermal cohesion. Is the target of linear IgA bullous dermatosis autoantibodies.

DomainsGene Ontology
PF01391 (3_Collagen)
GO:0005201 (enables) extracellular matrix structural constituent
GO:0005515 (enables) protein binding
GO:0030020 (enables) extracellular matrix structural constituent conferring tensile strength
GO:0007160 (involved in) cell-matrix adhesion
GO:0008544 (involved in) epidermis development
GO:0030198 (involved in) extracellular matrix organization
GO:0031581 (involved in) hemidesmosome assembly
GO:0005615 (is active in) extracellular space
GO:0031012 (is active in) extracellular matrix
GO:0005576 (located in) extracellular region
GO:0005604 (located in) basement membrane
GO:0005788 (located in) endoplasmic reticulum lumen
GO:0005886 (located in) plasma membrane
GO:0005887 (located in) integral component of plasma membrane
GO:0005911 (located in) cell-cell junction
GO:0016020 (located in) membrane
GO:0016021 (located in) integral component of membrane
GO:0030054 (located in) cell junction
GO:0030056 (located in) hemidesmosome
GO:0005581 (part of) collagen trimer
GO:0062023 (part of) collagen-containing extracellular matrix

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)