Click here to access PB0060 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0060 O00584 Ribonuclease T2 RNASET2 RNASE6PL, bA514O12.3 Homo_sapiens Participates as well in degradation of mitochondrion-associated cytosolic rRNAs (PubMed:30385512).

DomainsGene Ontology
PF00445 (Ribonuclease_T2)
GO:0003723 (enables) RNA binding
GO:0004518 (enables) nuclease activity
GO:0004519 (enables) endonuclease activity
GO:0004521 (enables) endoribonuclease activity
GO:0004540 (enables) ribonuclease activity
GO:0016787 (enables) hydrolase activity
GO:0016829 (enables) lyase activity
GO:0033897 (enables) ribonuclease T2 activity
GO:0002376 (involved in) immune system process
GO:0006401 (involved in) RNA catabolic process
GO:0045087 (involved in) innate immune response
GO:0090305 (involved in) nucleic acid phosphodiester bond hydrolysis
GO:0090501 (involved in) RNA phosphodiester bond hydrolysis
GO:0090502 (involved in) RNA phosphodiester bond hydrolysis, endonucleolytic
GO:0005576 (located in) extracellular region
GO:0005615 (located in) extracellular space
GO:0005739 (located in) mitochondrion
GO:0005758 (located in) mitochondrial intermembrane space
GO:0005764 (located in) lysosome
GO:0005783 (located in) endoplasmic reticulum
GO:0005788 (located in) endoplasmic reticulum lumen
GO:0035578 (located in) azurophil granule lumen
GO:0043202 (located in) lysosomal lumen
GO:0070062 (located in) extracellular exosome

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)