Click here to access PB0051 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0051 Q99715 Collagen alpha-1(XII) chain COL12A1 BA209D8.1, BTHLM2, COL12A1L, DJ234P15.1, EDSMYP, UCMD2, collagen type XII alpha 1 chain Homo_sapiens Type XII collagen interacts with type I collagen-containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix.

DomainsGene Ontology
PF00041 (18_fn3)
PF00092 (4_VWA)
PF01391 (4_Collagen)
GO:0030020 (enables) extracellular matrix structural constituent conferring tensile strength
GO:0007155 (involved in) cell adhesion
GO:0030199 (involved in) collagen fibril organization
GO:0035987 (involved in) endodermal cell differentiation
GO:0005576 (located in) extracellular region
GO:0005615 (located in) extracellular space
GO:0005788 (located in) endoplasmic reticulum lumen
GO:0070062 (located in) extracellular exosome
GO:1903561 (located in) extracellular vesicle
GO:0005581 (part of) collagen trimer
GO:0005595 (part of) collagen type XII trimer
GO:0062023 (part of) collagen-containing extracellular matrix

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)