Click here to access PB0048 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0048 O43405 Cochlin COCH COCH-5B2, COCH5B2, DFNA9, DFNB110 Homo_sapiens Plays a role in the control of cell shape and motility in the trabecular meshwork.

DomainsGene Ontology
PF00092 (2_VWA)
PF03815 (LCCL)
GO:0005515 (enables) protein binding
GO:0005518 (enables) collagen binding
GO:0007605 (involved in) sensory perception of sound
GO:0008360 (involved in) regulation of cell shape
GO:0042742 (involved in) defense response to bacterium
GO:0045089 (involved in) positive regulation of innate immune response
GO:0005576 (located in) extracellular region
GO:0031012 (located in) extracellular matrix
GO:0062023 (located in) collagen-containing extracellular matrix

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)