Click here to access PB0044 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0044 P29400 Collagen alpha-5(IV) chain COL4A5 ASLN, ATS, ATS1, CA54, collagen type IV alpha 5 chain Homo_sapiens Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.

DomainsGene Ontology
PF01391 (20_Collagen)
PF01413 (2_C4)
GO:0005201 (enables) extracellular matrix structural constituent
GO:0030020 (enables) extracellular matrix structural constituent conferring tensile strength
GO:0007528 (involved in) neuromuscular junction development
GO:0030198 (involved in) extracellular matrix organization
GO:0038063 (involved in) collagen-activated tyrosine kinase receptor signaling pathway
GO:0005604 (is active in) basement membrane
GO:0005615 (is active in) extracellular space
GO:0031012 (is active in) extracellular matrix
GO:0005576 (located in) extracellular region
GO:0005788 (located in) endoplasmic reticulum lumen
GO:0031594 (located in) neuromuscular junction
GO:0005581 (part of) collagen trimer
GO:0005587 (part of) collagen type IV trimer
GO:0062023 (part of) collagen-containing extracellular matrix

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)