PB0029

DATABASE

Click here to access PB0029 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0029	Q8WXD2	Secretogranin-3	SCG3	SGIII, secretogranin III	Homo_sapiens	May also play a role in angiogenesis. Promotes endothelial proliferation, migration and tube formation through MEK/ERK signaling pathway (PubMed:29154827).

Domains

Gene Ontology

PF15467 (SGIII)

GO:0003723 (enables) RNA binding GO:0005515 (enables) protein binding GO:0033366 (involved in) protein localization to secretory granule GO:0005576 (located in) extracellular region GO:0005788 (located in) endoplasmic reticulum lumen GO:0016020 (located in) membrane GO:0030133 (located in) transport vesicle GO:0030658 (located in) transport vesicle membrane GO:0030667 (located in) secretory granule membrane GO:0031410 (located in) cytoplasmic vesicle GO:0034774 (located in) secretory granule lumen

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|Q8WXD2|SCG3_HUMAN Secretogranin-3 OS=Homo sapiens OX=9606 GN=SCG3 PE=1 SV=3 MGFLGTGTWILVLVLPIQAFPKPGGSQDKSLHNRELSAERPLNEQIAEAEEDKIKKTYPP ENKPGQSNYSFVDNLNLLKAITEKEKIEKERQSIRSSPLDNKLNVEDVDSTKNRKLIDDY DSTKSGLDHKFQDDPDGLHQLDGTPLTAEDIVHKIAARIYEENDRAVFDKIVSKLLNLGL ITESQAHTLEDEVAEVLQKLISKEANNYEEDPNKPTSWTENQAGKIPEKVTPMAAIQDGL AKGENDETVSNTLTLTNGLERRTKTYSEDNFEELQYFPNFYALLKSIDSEKEAKEKETLI TIMKTLIDFVKMMVKYGTISPEEGVSYLENLDEMIALQTKNKLEKNATDNISKLFPAPSE KSHEETDSTKEEAAKMEKEYGSLKDSTKDDNSNPGGKTDEPKGKTEAYLEAIRKNIEWLK KHDKKGNKEDYDLSKMRDFINKQADAYVEKGILDKEEAEAIKRIYSSL >sp|A3KQQ9|SCG3_DANRE Secretogranin-3 OS=Danio rerio OX=7955 GN=scg3 PE=2 SV=1 MASKRLGFVVVLALVCQHINAFPTPAGPDDKYNRELTEEKPLEQQIAEADSIRKTESKPT PPAEEETNSEDDDITFLKALAEKSKESNNETPISDSANERLGADDTDSTKNRRLADDYDS TKNGMDYKYQDDPESFRQLDGTPLTAQDIVQKIANKIYEEDDRGVFDRIVSKLLKLGLIT DSQAETLEYEVAEALQDLITKNAKDNMIGDRSVDYPVSAAKDTQDEEDRPSPRFDEEDEV ENEGGDDANGDEPQEEESRDDTVRSDDSWDAVSDGNDRNELNPEDGLQDLQFFPNFYRLL KSLDSEQDKEERETLITIMKTLIDFVKMMVKYGTITPEEGVTYLENLDAMIALQTKNKLG KSLVPLSITPPTGKAADDDDNTKTEAAKMQKEYESLKDSTKDVQTAAEISHPGKSESYLE AIRKNIEWLKKHNKEGNKEDYDLSKLRDFMDQQVDSYIDKGILEKDEGDVIKRIYGSL
Selected proteins from model organisms >NP_033156.1 secretogranin-3 isoform 1 precursor [Mus musculus] MGFLWTGSWILVLVLNSGPIQAFPKPEGSQDKSLHNRELSAERPLNEQIAEAEADKIKKAFPSESKPSES NYSSVDNLNLLRAITEKETVEKERQSIRSPPFDNQLNVEDADSTKNRKLIDEYDSTKSGLDHKFQDDPDG LHQLDGTPLTAEDIVHKIATRIYEENDRGVFDKIVSKLLNLGLITESQAHTLEDEVAEALQKLISKEANN YEETLDKPTSRTENQDGKIPEKVTPVAAVQDGFTNRENDETVSNTLTLSNGLERRTNPHREDDFEELQYF PNFYALLTSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKLEKNT TDSKSKLFPAPPEKSQEETDSTKEEAAKMEKEYGSLKDSTKDDNSNLGGKTDEATGKTEAYLEAIRKNIE WLKKHNKKGNKEDYDLSKMRDFINQQADAYVEKGILDKEEANAIKRIYSSL >KAB0374934.1 hypothetical protein FD755_013426 [Muntiacus reevesi] MGFLWTGTWIVVLVLHSSPIQAFPKPAGSQDKPLHNRELSAERPLNEQIAEAEADKIKKTYPPENKPGESNYSFVDNLNL LKAITEKEKNEKERQSVKISPNDNKLNVEDVDSTKNRRLIDDYDSTKSGLDRKFQDDPDGLHQLDGTPLTAEDIVQKIAT RIYEENDRGVFDRIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANNYEEELNKPTSKTESQTAKIPEKVTPMAAIQ DAFTNGENDETVSNTLTLTNGLERRTKTYSEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYG TISPEEGVSYLENLDETIALQTKNKLEKNVTDNKSKLFPVPSEKSHEETDSTKEEAAKMEKEYGTLKDSTKDDDSNPRGK TDEPKGKTEAYLEAIRKNIDWLKKHNKKENKEDYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >KAB0343148.1 hypothetical protein FD754_020074 [Muntiacus muntjak] MGFLWTGTWIVVLVLHSSPIQAFPKPAGSQDKPLHNRELSAERPLNEQIAEAEADKIKKTYPPENKPGESNYSFVDNLNL LKAITEKEKNEKERQSVKISPNDNKLNVEDVDSTKNRRLIDDYDSTKSGLDRKFQDDPDGLHQLDGTPLTAEDIVQKIAT RIYEENDRGVFDRIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANNYEEELNKPTSKTESQTVKIPEKVTPMAAIQ DAFTNAENDETVSNTLTLTNGLERRTKTYSEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYG TISPEEGVSYLENLDETIALQTKNKLEKNVTDNKSKLFPVPSEKSHEEIDSTKEEAAKMEKEYGTLKDSTKDDDSNPRGK TDEPKGKTEAYLEAIRKNIDWLKKHNKKENKEDYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >KAF4017458.1 hypothetical protein G4228_009015 [Cervus hanglu yarkandensis] MGFLWTGTWIVVLVLHSSPIQAFPKPAGSQDKPLHNRELSAERPLNEQIAEAEADKIKKTYPPENKPGESNYSFVDNLNL LKAITEKEKNEKERKSVKISPNDNKLNVEDVDSTKNRRLIDDYDSTKSGLDRKFQDDPDGLHQLDGTPLTAEDIVQKIAT RIYKENDRGVFDRIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANNYEEELNKPTSKTESQTVKIPEKVTPMAAIQ DAFTNGENDETVSNTLTLTNGLERRTKTYSEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYG TISPEEGVSYLENLDETIALQTKNKLEKNVTDNKSKLFPVPSEKSHEETDSTKEEAAKMEKEYGTLKDSTKDDDSNPRGK TDEPKGKTEAYLEAIRKNIDWLKKHNKKENKEDYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >XP_043327918.1 secretogranin-3 isoform X1 [Cervus canadensis] MGFLWTGTWIVVLVLHSSPIQAFPKPAGSQDKPLHNRELSAERPLNEQIAEAEADKIKKTYPPENKPGESNYSFVDNLNL LKAITEKEKNEKERKSVKISPNDNKLNVEDVDSTKNRRLIDDYDSTKSGLDRKFQDDPDGLHQLDGTPLTAEDIVQKIAT RIYKENDRGVFDRIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANYYEEELNKPTSKTESQTVKIPEKVTPMAAIQ DAFTNGENDETVSNTLTLTNGLERRTKTYSEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYG TISPEEGVSYLENLDETIALQTKNKLEKNVTDNKSKLFPVPSEKSHEETDSTKEEAAKMEKEYGTLKDSTKDDDSNPRGK TDEPKGKTEAYLEAIRKNIDWLKKHNKKENKEDYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >NP_001079046.1 secretogranin-3 [Xenopus laevis] MGPKYVFITAIIGVFVHVQGFPNPSIKQDKDVHNRELSEERPLEEQIAEADTVSRGTSTENQEMLKNDSFADDLGFLMSM GEKDGDVKRSGSTRGSFGSNRGTLDDADSTKNLKLAEYFDTTKSMPDYKYEDDPDGLHQLDGTPLTAEDIVRKIATRIYE ENDRGVFDKIVSKLLNLGLITESQAYTLEDEVAEVLQQLIANEAKNREKEAGDLDYADVRSDVYDDDKREGKMETLNKNE DRESSETKNEDSLSTVERRNELSPEDDLQYFPNFNRLVKSLNSENDVKEKKTLLTIMKTLIDFVKMMVKYGTITPEEGVN YLENLDDMIAVQVKNKLGKNFGSHRNALPSEDKNADESDSTKEEAAKMEKEYELLKDSTKPEPNDAAESKPKGKAETYLE AIRKNIEWLKEHNKEANKGDNDLSKLKEFVNQQADSYVEKGILDKEEANVIKRIYSSL >NP_037375.2 secretogranin-3 isoform 1 precursor [Homo sapiens] MGFLGTGTWILVLVLPIQAFPKPGGSQDKSLHNRELSAERPLNEQIAEAEEDKIKKTYPPENKPGQSNYS FVDNLNLLKAITEKEKIEKERQSIRSSPLDNKLNVEDVDSTKNRKLIDDYDSTKSGLDHKFQDDPDGLHQ LDGTPLTAEDIVHKIAARIYEENDRAVFDKIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANNYEE DPNKPTSWTENQAGKIPEKVTPMAAIQDGLAKGENDETVSNTLTLTNGLERRTKTYSEDNFEELQYFPNF YALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDEMIALQTKNKLEKNATDN ISKLFPAPSEKSHEETDSTKEEAAKMEKEYGSLKDSTKDDNSNPGGKTDEPKGKTEAYLEAIRKNIEWLK KHDKKGNKEDYDLSKMRDFINKQADAYVEKGILDKEEAEAIKRIYSSL >NP_446308.1 secretogranin-3 precursor [Rattus norvegicus] MGFLWTGSWILVLVLNSGPIQAFPKPEGSQDKSLHNRELSAERPLNEQIAEAEADKIKKTYPSESKPSES NFSSVDNLNLLKAITEKETVEKAKQSIRSSPFDNRLNVDDADSTKNRKLTDEYDSTKSGLDRKVQDDPDG LHQLDGTPLTAEDIVHKIATRIYEENDRGVFDKIVSKLLNLGLITESQAHTLEDEVAEALQKLISKEANN YEEAPEKPTSRTENQDGKIPEKVTPVAATQDGFTNRENDDTVSNTLTLSNGLERRTNPHRDDDFEELQYF PNFYALLTSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKLEKNT TDSKSKLFPAPPEKSHEETDSTKEEAAKMEKEYGSLKDSTKDDNSNLGGKTDEAKGKTEAYLEAIRKNIE WLKKHNKKGNKEDYDLSKMRDFINQQADAYVEKGILDKEEANAIKRIYSSL >XP_040562244.1 secretogranin-3 isoform X1 [Gallus gallus] MFSFFSYIPHFQDSADVYIYAEDGRVRRHDFLLESVFCAPNRRKKNLFHIIIFPVLSLLASRAHGFPKPA GRDKAVHNRQLSVERPLEEQIAEAEADKNRKIGPTENKPEFRNYSFVDDLNLLKSVAERERNEKERESIR TSLYEQQLAIDDADSTKNRRLVDEYDSTKSGLDYKFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDR GVFDKIVSKLLNLGLITESQAYTLEDEVAEVLQQLIANEAKDREKEPEDFDYPPSRADSDSKEKQQEKMT SSKSDQDSFINGEIDDTLDNTWSSSNVLERRNELPSEDDFEDLQYFPNFYALLKSLNSETETKEKETLIT IMKTLIDFVKMMVKYGTITPEEGVSYLENLDTMIAVQTKKKLENPSIKTKPKQPTDKSSEEADSTKEEAA KMEKEYEISKDSTKNEEQNAAENSEEPRGKAEAYLEAIKKNIEWLKKHNKQGNKEDYDLSKLRDFIDQQA DAYVDKGILDKEEADVIKRIYGSL >XP_510407.2 secretogranin-3 isoform X1 [Pan troglodytes] MEHALPSSLPLQEGARVKLRPGAAVSASQELQHPQGGQRSPLPGDLTPARPNPAYPLTVECQRSCSRPVP APFPPHTRPPGSSCFYSSFSFITKATAPGAQRRAVTQAERGRMGFLGTSTWILVLVLPIQAFPKPGGSQD KSLHNRELSAERPLNEQIAEAEEDKIKKTYPPENKPGQSNYSFVDNLNLLKAITEKEKIEKERQSIRSSP LDNKLNVEDVDSTKNRKLIDDYDSTKSGLDHKFQDDPDGLHQLDGTPLTAEDIVHKIAARIYEENDRAVF DKIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANNYEEDPNKPTSWTENQAGKIPEKVTPMAAIQD GLAKGENDETVSNTLTLTNGLERRTKTYSEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLID FVKMMVKYGTISPEEGVSYLENLDEMIALQTKNKLEKNATDNISKLFPAPSEKSHEETDSTKEEAAKMEK EYGSLKDSTKDDNSNPGGKTDEPKGKTEAYLEAIRKNIEWLKKHDKKGNKEDYDLSKMRDFINKQADAYV EKGILDKEEAEAIKRIYSSL >XP_013965059.1 secretogranin-3 isoform X1 [Canis lupus familiaris] MGFLWTGTWILVLVLQSSPTQAFPKPGGSPGTRALVFPPPLISPRKDKPLHNRELSAERPLNEQIAEAEA DKIKKTYPPENKPGESNYSFVDNLNLLKAITEKEKIEKERQSIRSSPYDNKLNVEDVDSTKNRRLIDDYD STKSGLNHKFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDKIVSKLLNLGLITESQAHILED EVAEVLQKLISKEANTYEEEPNKPTSVTESQAGKIPEKVTPMAAIQDGFTNGQNDETVSNTLTLTNGLER RTKIYNEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENL DETIALQTKNKLEKNVTDNKSKLFPAPSEKSHEETDSTKEEAAKMEKEYGTLKDSTKDDNPRGKTDEPKG KTEAYLEAIRKNIEWLKKHNKKGNKEDYDLSKMRDFINQQADAYVEKGILDKEEANAIKRIYSSL >XP_010807648.1 secretogranin-3 isoform X1 [Bos taurus] MGFLWTGTWIVVLMLHSSPIQAFPKPAGSQDKPLHNRELSAERPLNEQIAEAEADEIKKTYPPENKPGES NYSFVDNLNLLKAITEKEKNEKERQSVKISPNDNKLNVEDVDSTKNRRLIDDYDSTKSGLDRKFQDDPDG LHQLDGTPLTAEDIVQKIATRIYEENDRGVFDRIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANN YEEELNKPTSKTESQTGKIPEKVTPMAAIQDAFTNGENDETVSNTLTLTNGLERRTKTYSEDNFEELQYF PNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKLEKNV TDNKSKLFAVPSEKSHEETDSTKEEAAKMEKEYGTLKDSTKDDDSNPRGKTDEHKGKTEAYLEAIRKNID WLKKHNKKENKEGQRNHKEVMVSLFTPCIQFKQHENQDYDLSKMRDFINQQADAYVEKGILDKEEADAIK RIYSSL >XP_001925946.1 secretogranin-3 [Sus scrofa] MGFLWTGTWIVVLVLHSSPIQAFPKPAGSQDKPLHNRELTAERPLNEQIAEAEADKIKKTYPPENKPGES NYSFVDNLNLLKAITDKEKNEKERQSVKSSPNDNKLNMEDVDSTKNRRLIDDYDSTKSGLDHKFQDDPDG LHQLDGTPLTAEDIVQKIATRIYEENDRGVFDKIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANN YEELSKPTSRTESQAGNIPEKVTPMAAIQDGLTNGENDETVSNTLTLTNGLERRTKTYSEDDFEELQFFP NFYALLKSIDSEKEVKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKLEKNVT DNKSKLFPAPSEKSHEETDSTKEEAAKMEKEYGTLKDSTKDDDSNPRGKTDEPKGKTEAYLEAIRKNIEW LKKHNKKEDKEDYDLSKMRDFINRQADAYVEKGILDKEEADAIKRIYSSL >NP_001126586.1 secretogranin-3 precursor [Pongo abelii] MGFLGTGTWILVLVLPIQAFPKPGGSQDKSLHNRELSAERPLNEQIAEAEEDKIKKTYPPENKPGQSNYS FVDNLNLLKAITEKEKIEKERQSIRSSPFDNKLNVEDVDSTKNRKLIDDYDSTKSGLDHKFQDDPDGLHQ LDRTPLTAEDIVHKIAARIYEENDRAVFDKIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANNYEE DPNKPTSWTENQAGKIPEKVTPMAAIQDGLAKGENDETVSNTLTLTNGLERRTKTYSEDNFEELQYFPNF YALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDEMIALQTKNKLEKNATDN ISKLFPAPSEKSHEETDSTKEEAAKMQKEYGSLKDSTKDDNSNPGGKTDEPKGKTEAYLEAIRKNIEWLK KHDKKGNKEDYDLSKMRDFINKQADAYVEKGILDKEEAEAIKRIYSSL >XP_002717826.1 PREDICTED: secretogranin-3 [Oryctolagus cuniculus] MGFFWTGTWILVLVLHSSPTEAFPKPGGGQDKSLHNRELSAERPLNEQIAEAEADKIKKANLPENKPGES NYSFVDNLNLLKAITEKEKNEKERQPIRSSPFDNKLNVEDVDSTKNRRLIDDYDSTKSGLDQKFQDDPDG LHQLDGTPLTAEDIVHKIATRIYEENDRGVFDRIVSKLLNLGLITESQAHTLEDEVAEALQQLISKEANN YEEELNKPTSRTENEAGKIPEKVTPMAAIQDDLTNVENDETVSDTLTLTNGLERRTKTYSEDNFEELQYF PNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDEMIALQTKNKLEKNA TDNKSKLFPAPSEKSHEEADSTKEEAAKMEKEYGTLKDSTKDDSSNLGGKTDEPKGKTEAYLEAIRKNIE WLKKHDKKGNKEDYDLSKMRDFINQQADAYVEKGILDQEEAKAIKRIYSSL >XP_010715658.1 secretogranin-3 [Meleagris gallopavo] MPPQPSARLRICGVRWGKLNGASTRSRAAVGADRDLKAVIELASRAHGFPKPASRDKAIHNRQLSVERPL EEQIAEAEADKNRKTAPTENKPEFRNYSFVDDLNLLKSVAERERNEKERESIRSSLYEQQLAIDDADSTK NRRLVDDYDSTKSGLDYKFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDKIVSKLLNLGLIT ESQAYTLEDEVAEVLQQLIANEAKDRENEPEDFDYPPSRADSDSKEKQQEKLTSSKSDQDSFINGEIDDT LDNTWSSSNILERRNELPSEDDFEDLQYFPNFYALLKSLNSETETKEKETLITIMKTLIDFVKMMVKYGT ITPEEGVSYLENLDTMIAVQTKKKLENPSTKSKPKQPADKSSEEADSTKEEAAKMEKEYEISKDSTKNEE QNAAGNSEEPRGKAEAYLEAIKKNIEWLKKHNKQGNKEDYDLSKLRDFIDQQADAYVDKGILDKEEADVI KRIYGSL >XP_003827887.1 secretogranin-3 isoform X1 [Pan paniscus] MEHALPSSLPLQEGARVKLRPGAAVSASQELQHPQGGQRSPLPGDLTPARPNPAYPLTVECQRSCSRPVP APLPPHTRPPGSSCFYSSFSFITKATAPGAQRRAVTQAERGRMGFLGTSTWILVLVLPIQAFPKPGGSQD KSLHNRELSAERPLNEQIAEAEEDKIKKTYPPENKPGQSNYSFVDNLNLLKAITEKEKIEKERQSIRSSP LDNKLNVEDVDSTKNRKLIDDYDSTKSGLDHKFQDDPDGLHQLDGTPLTAEDIVHKIAARIYEENDRAVF DKIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANNYEEDPNKPTSWTENQAGKIPEKVTPMAAIQD GLAKGENDETVSNILTLTNGLERRTKTYSEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLID FVKMMVKYGTISPEEGVSYLENLDEMIALQTKNKLEKNATDNISKLFPAPSEKSHEETDSTKEEAAKMEK EYGSLKDSTKDDNSNPGGKTDEPKGKTEAYLEAIRKNIEWLKKHDKKGNKEDYDLSKMRDFINKQADAYV EKGILDKEEAEAIKRIYSSL >XP_003987187.2 secretogranin-3 isoform X1 [Felis catus] MGFLWTGTWILVLVLQSSPVQAFPKPGGSQDKPLHNSELSAERPLNEQIAEAEADKIKKTYPPENKPGES NYSFVDNLNLLKAITEKEKVEKERQSIRSSPDDNKLNVEDVDSTKNRRLIDDYDSTKSGLNHKFQDDPDG LHQLDGTPLTAEDIVQKIATRIYEENDRGVFDKIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANT YEEEPNKPISVTESQTGKIPEKVTPMAAIQDGFTNGQNDETVSNTLTLTNGLERRTKIYNEDNFEELQYF PNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKLEKNV TDNKSKLFPAPSEKSHEETDSTKEEAAKMEKEYGALKDSTKADNPRGKTDEPKGKTEAYLEAIRKNIEWL KKHDKKGNKEDYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >XP_004010658.1 secretogranin-3 isoform X2 [Ovis aries] MGFLWTGTWIVVLVLHSSPIQAFPKPAGSQDKPLHNRELSAERPLNEQIAEAEADKIKKTYPPENKPGES NYSFVDNLNLLKAITEKEKNEKERQSVKISPNDNKLNVEDVDSTKNRRLIDDYDSTKSGLDRKFQDDPDG LHQLDGTPLTAEDIVQKIATRIYEENDRGVFDRIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANN YEEELNKPTSKTESHTGKIPEKVTPMAAIQNAFSNGENDETVSNTLTLTNGLERRTKTYSEDNFEELQYF PNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKLEKNV TDNKSKLFPVPSEKSHEETDSTKEEAAKMEKEYGTLKDSTKDDDSNPRGKTDEPKGKTEAYLEAIRKNID WLKKHNKKENKEDYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >XP_030858274.1 secretogranin-3 isoform X1 [Gorilla gorilla gorilla] MGFLGTGTWILVLVLPIQAFPKPGGSQDKSLHNRELSAERPLNEQIAEAEEDKIKKTYPPENKPGQSNYS FVDNLNLLKAITEKEKIEKERQSIRSSPLDNKLNVEDVDSTKNRKLIDDYDSTKSGLDHKFQDDPDGLHQ LDGTPLTAEDIVHKIAARIYEENDRAVFDKIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANNYEE DPNKPTSWTENQAGKIPEKVTPMAAIQDGLAKGENDETVSNTLTLTNGLERRTKTYSEDNFEELQYFPNF YALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDEMIALQTKNKLEKNATDN ISKLFPAPSEKSHEETDSTKEEAAKMEKEYGSLKDSTKDDNSNPGGKTDEPKGKTEAYLEAIRKNIEWLK KHDKKGNKEDYDLSKMRDFINKQADAYVEKGILDKEEAEAIKRIYSSL >XP_011486775.1 secretogranin-3 isoform X1 [Oryzias latipes] MASKAVCLFVLSQLLALNVVNPVYAFPTPSASTDADKSVYNQQLTEERPVQQQIAEADSVKAALQSAGGQ HPAASKESDQDSDDFTMLKSLADGQKSKEPSVVPVKKDDQYVPDESDSTKSRRLADDYDSTKKGMDYGKY QDDPESFRQVDGTPLTAEDIVQKIANKIYEEDDRGVFDRIVSKLLKLGLITESQADTLEYQVAEALQDLI TKNAKNNEIDDIESIDQAAGGEQEDQDSDTGTWEPPKRRYNEKEEDAAEADDEDVEDEVEREAEEDVNEA GDTWEKGTEDGNEVSPEDGLQDLQYFPNFYRLLKSLNLEKDTQERETLITIMKTLIDFVKMMVKYGTITP EEGVSYLENLDAMIAMQTKNKLGKALGLPDVTAPSEKDWDDDDNTKAEAAKMQKEYENLKDSTKEEQPPT ETNQPGKSEAYLEAIRKNIEWLKKHNKEDGKEDYDLSKLKDFMDQQLDSYIDKGIIAKEEGDTIKRIYSS L >XP_013225016.1 secretogranin-3 isoform X1 [Columba livia] MILSNAAKDSFINGETDDTLDNTWSPSNALERRNELPSEDNFEDLQYFPNFYALLKSLNSETEAKEKETL ITIMKTLIDFVKMMVKYGTITPEEAVSYLENLDTMIAEQTKKRLENPSTKARTKLPADKSSEEADSTKEE AAKMEKEYEISKDSTKNEEQKAAGNSEEPRGKAEAYLEAIRKNIEWLKKHNKQGNKEDYDLPKLRDFIDQ QADAYVDEGILDKEEADVIKRIYGSL >XP_013822597.2 PREDICTED: secretogranin-3 isoform X1 [Capra hircus] MGFLWTGTWIVVLVLHSSPIQAFPKPAGSQDKPLHNRELSAERPLNEQIAEAEADKIKKTYPPENKPGES NYSFVDNLNLLKAITEKEKNKKERQSVKISPNDNKLNVEDVDSTKNRRLIDDYDSTKSGLDRKFQDDPDG LHQLDGTPLTAEDIVQKIATRIYEENDRGVFDRIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANN YEEELNKPTSKTESQTGKIPEKVTPMAAIQNAFTNGENDETVSNTLTLTNGLERRTKTYSEDNFEELQYF PNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKLEKNV TDNKSKLFPVPSEKSHEETDSTKEEAAKMEKEYGTLKDSTKDDDSNPRGKTDEPKGKTEAYLEAIRKNID WLKKHNIKENKEGQRNHKEVMVSLFTPCIQFKQHENQDYDLSKMRDFINQQADAYVEKGILDKEEADAIK RIYSSL >XP_006017995.1 secretogranin-3 isoform X1 [Alligator sinensis] MVLKLAVVIQVLSLTVGHVHGFPKPEGNRDKAIHNRQLSVERPLEEQIAEAETDKIRKTVSTENKPEFRN YSFADDLNLLQSVAEKERNEKERASIRSSLYEQQLALDDADSTKNRRLVDDYDSTKSGLDYKFQDDPDGL HQLDGTPLTAEDIVQKIATRIYEENDRGVFDKIVSKLLNLGLITESQAYTLEDEVAEVLQQLIANEANDG EKESEALDYPPSRTDSDTEEKQEENMTPSNADQDGFINGESDDTLDNTWPSSNALERRNELPSDNNFEDL QYFPNFYALLKSLNSETEAKEKETLITIMKTLIDFVKMMVKYGTITPEEGVSYLENLDEMIALQTKNKLE KPSTDTKNKLLADKSNEETDSTKEEAAKMEKEYETLKDSTKIEEQNTAGNTNQPKGKAEAYLEAIRKNIE WLKKHSKQAPKEDYDLSKLRDFIDEQADAYVDKGILDKEEADVIKRIYSSL >XP_006261125.1 PREDICTED: secretogranin-3 isoform X1 [Alligator mississippiensis] MVLKLAVVIQVLSLTLGHVHGFPKPEGNRDKAIHNRQLSVERPLEEQIAEAETDKIRKTVSTENKPEFRN YSFADDLNLLQSVAEKERNEKERASIRSSLYEQQLALDDADSTKNRRLVDDYDSTKSGLDYKFQDDPDGL HQLDGTPLTAEDIVQKIATRIYEENDRGVFDKIVSKLLNLGLITESQAYTLEDEVAEVLQQLIANEANDG EKESEALDYPPSRTDSDTEEKQEENMTPSNADQDGFINGESDDTLDNTWPSSNALERRNELPSDNNFEDL QYFPNFYALLKSLNSETEAKEKETLITIMKTLIDFVKMMVKYGTITPEEGVSYLENLDEMIALQTKNKLE KPSIDTKNKLLADKSNEETDSTKEEAAKMEKEYETLKDSTKIEEQNTAGNTNQPKGKAEAYLEAIRKNIE WLKKHSKQGPKEDYDLSKLRDFIDEQADAYVDKGILDKEEADVIKRIYSSL >XP_015809394.1 PREDICTED: secretogranin-3 isoform X1 [Nothobranchius furzeri] MASKYFGLFVLVQLFVLEVDNQTFAFPTPTASTDDKAVYNRQLTEERPLQEQIAEADSVKAAVQSAESKQ PAAFKDAESEQASDDFTMLKSLADGQKSKDSREVLVKKEDHHVPDEADSTKSRRLADDYDSTKNGMDYGK YQDDTESFRQVDGTPLTAEDIVQKIANKIYEEDDRGVFDRIISKLLKLGLITENQADSLEYQVAEALQDL ITKNAKNNEVEDTENIAQDTGGEQDDQGADMDTWEPRKRSYNEEEEEEEDNDDEQIEDDVDRDAEEEMEA ADNTWDKDTEEGNEVGQGDGLQDLQYFPNFYQLLRSLNSEKDAQERETLITIMKTLIDFVKMMVKYGTIT PEEGVSYLENLDAMIAMQTKNKLGKSLGLPEVGGPNGKNMDEDDNTKSETAKMQKEYENLRDSTKEEQPT AESTLDQPGKSETYLEAIRKNIEWLKKHNKDDGKDDYDLSKLKDFMDQQVESYIEKGIIAKDEGDTIKRI YGSL >XP_020724875.1 secretogranin-3 isoform X1 [Odocoileus virginianus texanus] MGFLWTGTWIVVLVLHSSPIQAFPKPAGSRDKPLHNRELSAERPLNEQIAEAEADKIKKTYPPENKPGES NYSFVDNLNLLKAITEKEKNEKERQSVKISPNDNKLNMDDVDSTKNRRLIDDYDSTKSGLDRKFQGKFQD DPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDRIVSKLLNLGLITESQAHTLEDEVAEVLQKLISK EANNYEEELNKPTSKTESQTVKIPEKVTPMAAIQDAFTSGENDETVSNTLTLTNGLERRTKTYSEDNFEE LQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKL EKNVTDNKSKLFPGPSEKSHEETDSTKEEAAKMEKEYGTLKDSTKDDDPNPRGKTDEPKGKTEAYLEAIR KNIDWLKKHNKKENKEDYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >XP_030270157.1 secretogranin-3 isoform X1 [Sparus aurata] MASKSVGLFVLFHLVVLNVVSQSSAFPTPTASADDKTVYNRQLTEERPLQEQIAEADSVKAAVQSAESQR PASSKDGESQQDLDDLTVLKSLADGQKSKEAAEEVLLKKEEQYVPDESDSTKSRRLAEDYDSTKNGMDYG KYPDDTESFRQVDGTPLTAEDIVQKIANKIYEEDDRGVFDRIVSKLLKLGLITDSQADTLEYQVAEALQD LITKNAKNNEIEDIESNNQETRGEQDDQGSDANTDAWDQPRRRYNDGDEEEDDDEIEDEVDRDAEEEEGD ADANTWDKDAEEGNEVSPEDGLQDLQYFPNFYRLLRSLDSDQDTQERETLITIMKTLIDFVKMMVKYGTI TPEEGVSYLENLDAMIAMQTKNKLGKSLGPPDVIGPNGKNLDEDDNTKAEAAKMQKEYENLKDSTKEEQP STESSQPGKSETYLEAIRKNIEWLKKHSKEEGKDDYDLSKLKDFMDQQVDSYIEKGIIAKDEGDTIKRIY SSL >sp|A3KQQ9|SCG3_DANRE Secretogranin-3 OS=Danio rerio OX=7955 GN=scg3 PE=2 SV=1 MASKRLGFVVVLALVCQHINAFPTPAGPDDKYNRELTEEKPLEQQIAEADSIRKTESKPT PPAEEETNSEDDDITFLKALAEKSKESNNETPISDSANERLGADDTDSTKNRRLADDYDS TKNGMDYKYQDDPESFRQLDGTPLTAQDIVQKIANKIYEEDDRGVFDRIVSKLLKLGLIT DSQAETLEYEVAEALQDLITKNAKDNMIGDRSVDYPVSAAKDTQDEEDRPSPRFDEEDEV ENEGGDDANGDEPQEEESRDDTVRSDDSWDAVSDGNDRNELNPEDGLQDLQFFPNFYRLL KSLDSEQDKEERETLITIMKTLIDFVKMMVKYGTITPEEGVTYLENLDAMIALQTKNKLG KSLVPLSITPPTGKAADDDDNTKTEAAKMQKEYESLKDSTKDVQTAAEISHPGKSESYLE AIRKNIEWLKKHNKEGNKEDYDLSKLRDFMDQQVDSYIDKGILEKDEGDVIKRIYGSL >XP_040198616.1 secretogranin-3 [Rana temporaria] MGVITFLVCTAILYNVQGFPKPDTTQDKALHNRELSVERPLEEQIAEADTVSRGASTETKNDSLVDDLSF LMSVAEKEKNVKRSGGVISTTNGQKAAPEDGDTTKSLKPVEYFDSTKGGLDFKDEDDPDGLHQLDGTPLT AEDIVQKIAMRIYEENDRGVFDKIVSKLLNLGLITESQAYALEDEVAVVLQQLIANEAKNREKGSEDVDY PAIKTDANTEEKQEGRMEPQEKEVSEQSTNVADNDWSPAPNMERRNEMPLEENFEDLQYFPNFYQLIKSL NAENDAKEKETLITIMKTLIDFVKMMVKYGTITPEEGVNYLENLDTMIAVQTKNKLGKNSTYQKNGLLSA DKTDEETDSTKEAAANMEKEFEKFKDSTKLEEPKETTDVPTLKGKGEAYLEAIRKNIEWLKKHKQGGKED YDLSKLRDFIDQQADSYVEKGILDQEEANVIKRIYSSL
Mafft alignment of selected proteins >NP_033156.1 secretogranin-3 isoform 1 precursor [Mus musculus] ------------------------------------------------------------ ----------------------------------------------------M------- ------------------------------------GFLWTGSWILVLVLNSGPIQAFPK PEGS----------------Q-DKSLHNRELSAERPLNEQIAEAEADKIKKAFPSESKPS ----ESNYSSVDNLNLLRAITEKETVEKERQSIRSPPFDNQLNVEDADSTKNRKLIDEYD STKSGLDH----KFQDDPDGLHQLDGTPLTAEDIVHKIATRIYEENDRGVFDKIVSKLLN LGLITESQAHTLEDEVAEALQKLISKEANNYE----ETLDKPTSRTENQD---------G KIPEKVTPVAAVQDG------------FTNRENDETVS-NTLTLSNGLERRTNPHREDDF EELQYFPNFYALLTSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENL DETIALQTKNKLEKNTTDSKSKLFPAPP-EKSQEETDSTKEEAAKMEKEYGSLKDSTKDD NSNLGGKTDEATGKTEAYLEAIRKNIEWLKKHNKKGNKE--------------------- ----DYDLSKMRDFINQQADAYVEKGILDKEEANAIKRIYSSL >KAB0374934.1 hypothetical protein FD755_013426 [Muntiacus reevesi] ------------------------------------------------------------ ----------------------------------------------------M------- ------------------------------------GFLWTGTWIVVLVLHSSPIQAFPK PAGS----------------Q-DKPLHNRELSAERPLNEQIAEAEADKIKKTYPPENKPG ----ESNYSFVDNLNLLKAITEKEKNEKERQSVKISPNDNKLNVEDVDSTKNRRLIDDYD STKSGLDR----KFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDRIVSKLLN LGLITESQAHTLEDEVAEVLQKLISKEANNYE----EELNKPTSKTESQT---------A KIPEKVTPMAAIQDA------------FTNGENDETVS-NTLTLTNGLERRTKTYSEDNF EELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENL DETIALQTKNKLEKNVTDNKSKLFPVPS-EKSHEETDSTKEEAAKMEKEYGTLKDSTKDD DSNPRGKTDEPKGKTEAYLEAIRKNIDWLKKHNKKENKE--------------------- ----DYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >KAB0343148.1 hypothetical protein FD754_020074 [Muntiacus muntjak] ------------------------------------------------------------ ----------------------------------------------------M------- ------------------------------------GFLWTGTWIVVLVLHSSPIQAFPK PAGS----------------Q-DKPLHNRELSAERPLNEQIAEAEADKIKKTYPPENKPG ----ESNYSFVDNLNLLKAITEKEKNEKERQSVKISPNDNKLNVEDVDSTKNRRLIDDYD STKSGLDR----KFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDRIVSKLLN LGLITESQAHTLEDEVAEVLQKLISKEANNYE----EELNKPTSKTESQT---------V KIPEKVTPMAAIQDA------------FTNAENDETVS-NTLTLTNGLERRTKTYSEDNF EELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENL DETIALQTKNKLEKNVTDNKSKLFPVPS-EKSHEEIDSTKEEAAKMEKEYGTLKDSTKDD DSNPRGKTDEPKGKTEAYLEAIRKNIDWLKKHNKKENKE--------------------- ----DYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >KAF4017458.1 hypothetical protein G4228_009015 [Cervus hanglu yarkandensis] ------------------------------------------------------------ ----------------------------------------------------M------- ------------------------------------GFLWTGTWIVVLVLHSSPIQAFPK PAGS----------------Q-DKPLHNRELSAERPLNEQIAEAEADKIKKTYPPENKPG ----ESNYSFVDNLNLLKAITEKEKNEKERKSVKISPNDNKLNVEDVDSTKNRRLIDDYD STKSGLDR----KFQDDPDGLHQLDGTPLTAEDIVQKIATRIYKENDRGVFDRIVSKLLN LGLITESQAHTLEDEVAEVLQKLISKEANNYE----EELNKPTSKTESQT---------V KIPEKVTPMAAIQDA------------FTNGENDETVS-NTLTLTNGLERRTKTYSEDNF EELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENL DETIALQTKNKLEKNVTDNKSKLFPVPS-EKSHEETDSTKEEAAKMEKEYGTLKDSTKDD DSNPRGKTDEPKGKTEAYLEAIRKNIDWLKKHNKKENKE--------------------- ----DYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >XP_043327918.1 secretogranin-3 isoform X1 [Cervus canadensis] ------------------------------------------------------------ ----------------------------------------------------M------- ------------------------------------GFLWTGTWIVVLVLHSSPIQAFPK PAGS----------------Q-DKPLHNRELSAERPLNEQIAEAEADKIKKTYPPENKPG ----ESNYSFVDNLNLLKAITEKEKNEKERKSVKISPNDNKLNVEDVDSTKNRRLIDDYD STKSGLDR----KFQDDPDGLHQLDGTPLTAEDIVQKIATRIYKENDRGVFDRIVSKLLN LGLITESQAHTLEDEVAEVLQKLISKEANYYE----EELNKPTSKTESQT---------V KIPEKVTPMAAIQDA------------FTNGENDETVS-NTLTLTNGLERRTKTYSEDNF EELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENL DETIALQTKNKLEKNVTDNKSKLFPVPS-EKSHEETDSTKEEAAKMEKEYGTLKDSTKDD DSNPRGKTDEPKGKTEAYLEAIRKNIDWLKKHNKKENKE--------------------- ----DYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >NP_001079046.1 secretogranin-3 [Xenopus laevis] ------------------------------------------------------------ ----------------------------------------------------M------- --------------------------------------GPKYVFITAIIGVFVHVQGFPN PSIK----------------Q-DKDVHNRELSEERPLEEQI--AEADTVSRGTSTENQEM ----LKNDSFADDLGFLMSMGEKDGDVKRSGSTRGSFGSNRGTLDDADSTKNLKLAEYFD TTKSMPDY----KYEDDPDGLHQLDGTPLTAEDIVRKIATRIYEENDRGVFDKIVSKLLN LGLITESQAYTLEDEVAEVLQQLIANEAKNREKEA-GDLDYADVRSDVYDD--------D KREGKMETLNKNED----------------RESSETKN---EDSLSTVERRNELSPED-- -DLQYFPNFNRLVKSLNSENDVKEKKTLLTIMKTLIDFVKMMVKYGTITPEEGVNYLENL DDMIAVQVKNKLGKNFGSHRNAL---PSEDKNADESDSTKEEAAKMEKEYELLKDSTKPE PNDAAES--KPKGKAETYLEAIRKNIEWLKEHNKEANKG--------------------- ----DNDLSKLKEFVNQQADSYVEKGILDKEEANVIKRIYSSL >NP_037375.2 secretogranin-3 isoform 1 precursor [Homo sapiens] ------------------------------------------------------------ ----------------------------------------------------M------- ------------------------------------GFLGTGTWILVLVL---PIQAFPK PGGS----------------Q-DKSLHNRELSAERPLNEQIAEAEEDKIKKTYPPENKPG ----QSNYSFVDNLNLLKAITEKEKIEKERQSIRSSPLDNKLNVEDVDSTKNRKLIDDYD STKSGLDH----KFQDDPDGLHQLDGTPLTAEDIVHKIAARIYEENDRAVFDKIVSKLLN LGLITESQAHTLEDEVAEVLQKLISKEANNYE----EDPNKPTSWTENQA---------G KIPEKVTPMAAIQDG------------LAKGENDETVS-NTLTLTNGLERRTKTYSEDNF EELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENL DEMIALQTKNKLEKNATDNISKLFPAPS-EKSHEETDSTKEEAAKMEKEYGSLKDSTKDD NSNPGGKTDEPKGKTEAYLEAIRKNIEWLKKHDKKGNKE--------------------- ----DYDLSKMRDFINKQADAYVEKGILDKEEAEAIKRIYSSL >NP_446308.1 secretogranin-3 precursor [Rattus norvegicus] ------------------------------------------------------------ ----------------------------------------------------M------- ------------------------------------GFLWTGSWILVLVLNSGPIQAFPK PEGS----------------Q-DKSLHNRELSAERPLNEQIAEAEADKIKKTYPSESKPS ----ESNFSSVDNLNLLKAITEKETVEKAKQSIRSSPFDNRLNVDDADSTKNRKLTDEYD STKSGLDR----KVQDDPDGLHQLDGTPLTAEDIVHKIATRIYEENDRGVFDKIVSKLLN LGLITESQAHTLEDEVAEALQKLISKEANNYE----EAPEKPTSRTENQD---------G KIPEKVTPVAATQDG------------FTNRENDDTVS-NTLTLSNGLERRTNPHRDDDF EELQYFPNFYALLTSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENL DETIALQTKNKLEKNTTDSKSKLFPAPP-EKSHEETDSTKEEAAKMEKEYGSLKDSTKDD NSNLGGKTDEAKGKTEAYLEAIRKNIEWLKKHNKKGNKE--------------------- ----DYDLSKMRDFINQQADAYVEKGILDKEEANAIKRIYSSL >XP_040562244.1 secretogranin-3 isoform X1 [Gallus gallus] ------------------------------------------------------------ ----------------------------------------------------MFSFFSYI PHFQDSADVYIYAEDGRVRRHDFLLESVFCAPNRRKKNLFHIIIFPVLSLLASRAHGFPK PAG-----------------R-DKAVHNRQLSVERPLEEQIAEAEADKNRKIGPTENKPE ----FRNYSFVDDLNLLKSVAERERNEKERESIRTSLYEQQLAIDDADSTKNRRLVDEYD STKSGLDY----KFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDKIVSKLLN LGLITESQAYTLEDEVAEVLQQLIANEAKDREKEP-EDFDYPPSRADSDSK--------E KQQEKMTSSKSDQDS------------FINGEIDDTLD-NTWSSSNVLERRNELPSEDDF EDLQYFPNFYALLKSLNSETETKEKETLITIMKTLIDFVKMMVKYGTITPEEGVSYLENL DTMIAVQTKKKLENPSIKTKPKQ---PT-DKSSEEADSTKEEAAKMEKEYEISKDSTKNE EQNAAENSEEPRGKAEAYLEAIKKNIEWLKKHNKQGNKE--------------------- ----DYDLSKLRDFIDQQADAYVDKGILDKEEADVIKRIYGSL >XP_510407.2 secretogranin-3 isoform X1 [Pan troglodytes] MEHALPSSLPLQEGARVKLRPGAAVSASQELQHPQGGQRSPLPGDLTPARPNPAYPLTVE CQRSCSRPVPAPFPPHTRPPGSSCFYSSFSFITKATAPGAQRRAVTQAERGRM------- ------------------------------------GFLGTSTWILVLVL---PIQAFPK PGGS----------------Q-DKSLHNRELSAERPLNEQIAEAEEDKIKKTYPPENKPG ----QSNYSFVDNLNLLKAITEKEKIEKERQSIRSSPLDNKLNVEDVDSTKNRKLIDDYD STKSGLDH----KFQDDPDGLHQLDGTPLTAEDIVHKIAARIYEENDRAVFDKIVSKLLN LGLITESQAHTLEDEVAEVLQKLISKEANNYE----EDPNKPTSWTENQA---------G KIPEKVTPMAAIQDG------------LAKGENDETVS-NTLTLTNGLERRTKTYSEDNF EELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENL DEMIALQTKNKLEKNATDNISKLFPAPS-EKSHEETDSTKEEAAKMEKEYGSLKDSTKDD NSNPGGKTDEPKGKTEAYLEAIRKNIEWLKKHDKKGNKE--------------------- ----DYDLSKMRDFINKQADAYVEKGILDKEEAEAIKRIYSSL >XP_013965059.1 secretogranin-3 isoform X1 [Canis lupus familiaris] ------------------------------------------------------------ ----------------------------------------------------M------- ------------------------------------GFLWTGTWILVLVLQSSPTQAFPK PGGSPGTRALVFPPPLISPRK-DKPLHNRELSAERPLNEQIAEAEADKIKKTYPPENKPG ----ESNYSFVDNLNLLKAITEKEKIEKERQSIRSSPYDNKLNVEDVDSTKNRRLIDDYD STKSGLNH----KFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDKIVSKLLN LGLITESQAHILEDEVAEVLQKLISKEANTYE----EEPNKPTSVTESQA---------G KIPEKVTPMAAIQDG------------FTNGQNDETVS-NTLTLTNGLERRTKIYNEDNF EELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENL DETIALQTKNKLEKNVTDNKSKLFPAPS-EKSHEETDSTKEEAAKMEKEYGTLKDSTKDD --NPRGKTDEPKGKTEAYLEAIRKNIEWLKKHNKKGNKE--------------------- ----DYDLSKMRDFINQQADAYVEKGILDKEEANAIKRIYSSL >XP_010807648.1 secretogranin-3 isoform X1 [Bos taurus] ------------------------------------------------------------ ----------------------------------------------------M------- ------------------------------------GFLWTGTWIVVLMLHSSPIQAFPK PAGS----------------Q-DKPLHNRELSAERPLNEQIAEAEADEIKKTYPPENKPG ----ESNYSFVDNLNLLKAITEKEKNEKERQSVKISPNDNKLNVEDVDSTKNRRLIDDYD STKSGLDR----KFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDRIVSKLLN LGLITESQAHTLEDEVAEVLQKLISKEANNYE----EELNKPTSKTESQT---------G KIPEKVTPMAAIQDA------------FTNGENDETVS-NTLTLTNGLERRTKTYSEDNF EELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENL DETIALQTKNKLEKNVTDNKSKLFAVPS-EKSHEETDSTKEEAAKMEKEYGTLKDSTKDD DSNPRGKTDEHKGKTEAYLEAIRKNIDWLKKHNKKENKEGQRNHKEVMVSLFTPCIQFKQ HENQDYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >XP_001925946.1 secretogranin-3 [Sus scrofa] ------------------------------------------------------------ ----------------------------------------------------M------- ------------------------------------GFLWTGTWIVVLVLHSSPIQAFPK PAGS----------------Q-DKPLHNRELTAERPLNEQIAEAEADKIKKTYPPENKPG ----ESNYSFVDNLNLLKAITDKEKNEKERQSVKSSPNDNKLNMEDVDSTKNRRLIDDYD STKSGLDH----KFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDKIVSKLLN LGLITESQAHTLEDEVAEVLQKLISKEANNY-----EELSKPTSRTESQA---------G NIPEKVTPMAAIQDG------------LTNGENDETVS-NTLTLTNGLERRTKTYSEDDF EELQFFPNFYALLKSIDSEKEVKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENL DETIALQTKNKLEKNVTDNKSKLFPAPS-EKSHEETDSTKEEAAKMEKEYGTLKDSTKDD DSNPRGKTDEPKGKTEAYLEAIRKNIEWLKKHNKKEDKE--------------------- ----DYDLSKMRDFINRQADAYVEKGILDKEEADAIKRIYSSL >NP_001126586.1 secretogranin-3 precursor [Pongo abelii] ------------------------------------------------------------ ----------------------------------------------------M------- ------------------------------------GFLGTGTWILVLVL---PIQAFPK PGGS----------------Q-DKSLHNRELSAERPLNEQIAEAEEDKIKKTYPPENKPG ----QSNYSFVDNLNLLKAITEKEKIEKERQSIRSSPFDNKLNVEDVDSTKNRKLIDDYD STKSGLDH----KFQDDPDGLHQLDRTPLTAEDIVHKIAARIYEENDRAVFDKIVSKLLN LGLITESQAHTLEDEVAEVLQKLISKEANNYE----EDPNKPTSWTENQA---------G KIPEKVTPMAAIQDG------------LAKGENDETVS-NTLTLTNGLERRTKTYSEDNF EELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENL DEMIALQTKNKLEKNATDNISKLFPAPS-EKSHEETDSTKEEAAKMQKEYGSLKDSTKDD NSNPGGKTDEPKGKTEAYLEAIRKNIEWLKKHDKKGNKE--------------------- ----DYDLSKMRDFINKQADAYVEKGILDKEEAEAIKRIYSSL >XP_002717826.1 PREDICTED: secretogranin-3 [Oryctolagus cuniculus] ------------------------------------------------------------ ----------------------------------------------------M------- ------------------------------------GFFWTGTWILVLVLHSSPTEAFPK PGGG----------------Q-DKSLHNRELSAERPLNEQIAEAEADKIKKANLPENKPG ----ESNYSFVDNLNLLKAITEKEKNEKERQPIRSSPFDNKLNVEDVDSTKNRRLIDDYD STKSGLDQ----KFQDDPDGLHQLDGTPLTAEDIVHKIATRIYEENDRGVFDRIVSKLLN LGLITESQAHTLEDEVAEALQQLISKEANNYE----EELNKPTSRTENEA---------G KIPEKVTPMAAIQDD------------LTNVENDETVS-DTLTLTNGLERRTKTYSEDNF EELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENL DEMIALQTKNKLEKNATDNKSKLFPAPS-EKSHEEADSTKEEAAKMEKEYGTLKDSTKDD SSNLGGKTDEPKGKTEAYLEAIRKNIEWLKKHDKKGNKE--------------------- ----DYDLSKMRDFINQQADAYVEKGILDQEEAKAIKRIYSSL >XP_010715658.1 secretogranin-3 [Meleagris gallopavo] ------------------------------------------------------------ ----------------------------------------------------M------- PP-QPSA---------RLRICGVRWGKLNGASTRSRAAVGADRDLKAVIELASRAHGFPK PAS-----------------R-DKAIHNRQLSVERPLEEQIAEAEADKNRKTAPTENKPE ----FRNYSFVDDLNLLKSVAERERNEKERESIRSSLYEQQLAIDDADSTKNRRLVDDYD STKSGLDY----KFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDKIVSKLLN LGLITESQAYTLEDEVAEVLQQLIANEAKDRENEP-EDFDYPPSRADSDSK--------E KQQEKLTSSKSDQDS------------FINGEIDDTLD-NTWSSSNILERRNELPSEDDF EDLQYFPNFYALLKSLNSETETKEKETLITIMKTLIDFVKMMVKYGTITPEEGVSYLENL DTMIAVQTKKKLENPSTKSKPKQ---PA-DKSSEEADSTKEEAAKMEKEYEISKDSTKNE EQNAAGNSEEPRGKAEAYLEAIKKNIEWLKKHNKQGNKE--------------------- ----DYDLSKLRDFIDQQADAYVDKGILDKEEADVIKRIYGSL >XP_003827887.1 secretogranin-3 isoform X1 [Pan paniscus] MEHALPSSLPLQEGARVKLRPGAAVSASQELQHPQGGQRSPLPGDLTPARPNPAYPLTVE CQRSCSRPVPAPLPPHTRPPGSSCFYSSFSFITKATAPGAQRRAVTQAERGRM------- ------------------------------------GFLGTSTWILVLVL---PIQAFPK PGGS----------------Q-DKSLHNRELSAERPLNEQIAEAEEDKIKKTYPPENKPG ----QSNYSFVDNLNLLKAITEKEKIEKERQSIRSSPLDNKLNVEDVDSTKNRKLIDDYD STKSGLDH----KFQDDPDGLHQLDGTPLTAEDIVHKIAARIYEENDRAVFDKIVSKLLN LGLITESQAHTLEDEVAEVLQKLISKEANNYE----EDPNKPTSWTENQA---------G KIPEKVTPMAAIQDG------------LAKGENDETVS-NILTLTNGLERRTKTYSEDNF EELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENL DEMIALQTKNKLEKNATDNISKLFPAPS-EKSHEETDSTKEEAAKMEKEYGSLKDSTKDD NSNPGGKTDEPKGKTEAYLEAIRKNIEWLKKHDKKGNKE--------------------- ----DYDLSKMRDFINKQADAYVEKGILDKEEAEAIKRIYSSL >XP_003987187.2 secretogranin-3 isoform X1 [Felis catus] ------------------------------------------------------------ ----------------------------------------------------M------- ------------------------------------GFLWTGTWILVLVLQSSPVQAFPK PGGS----------------Q-DKPLHNSELSAERPLNEQIAEAEADKIKKTYPPENKPG ----ESNYSFVDNLNLLKAITEKEKVEKERQSIRSSPDDNKLNVEDVDSTKNRRLIDDYD STKSGLNH----KFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDKIVSKLLN LGLITESQAHTLEDEVAEVLQKLISKEANTYE----EEPNKPISVTESQT---------G KIPEKVTPMAAIQDG------------FTNGQNDETVS-NTLTLTNGLERRTKIYNEDNF EELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENL DETIALQTKNKLEKNVTDNKSKLFPAPS-EKSHEETDSTKEEAAKMEKEYGALKDSTKAD --NPRGKTDEPKGKTEAYLEAIRKNIEWLKKHDKKGNKE--------------------- ----DYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >XP_004010658.1 secretogranin-3 isoform X2 [Ovis aries] ------------------------------------------------------------ ----------------------------------------------------M------- ------------------------------------GFLWTGTWIVVLVLHSSPIQAFPK PAGS----------------Q-DKPLHNRELSAERPLNEQIAEAEADKIKKTYPPENKPG ----ESNYSFVDNLNLLKAITEKEKNEKERQSVKISPNDNKLNVEDVDSTKNRRLIDDYD STKSGLDR----KFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDRIVSKLLN LGLITESQAHTLEDEVAEVLQKLISKEANNYE----EELNKPTSKTESHT---------G KIPEKVTPMAAIQNA------------FSNGENDETVS-NTLTLTNGLERRTKTYSEDNF EELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENL DETIALQTKNKLEKNVTDNKSKLFPVPS-EKSHEETDSTKEEAAKMEKEYGTLKDSTKDD DSNPRGKTDEPKGKTEAYLEAIRKNIDWLKKHNKKENKE--------------------- ----DYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >XP_030858274.1 secretogranin-3 isoform X1 [Gorilla gorilla gorilla] ------------------------------------------------------------ ----------------------------------------------------M------- ------------------------------------GFLGTGTWILVLVL---PIQAFPK PGGS----------------Q-DKSLHNRELSAERPLNEQIAEAEEDKIKKTYPPENKPG ----QSNYSFVDNLNLLKAITEKEKIEKERQSIRSSPLDNKLNVEDVDSTKNRKLIDDYD STKSGLDH----KFQDDPDGLHQLDGTPLTAEDIVHKIAARIYEENDRAVFDKIVSKLLN LGLITESQAHTLEDEVAEVLQKLISKEANNYE----EDPNKPTSWTENQA---------G KIPEKVTPMAAIQDG------------LAKGENDETVS-NTLTLTNGLERRTKTYSEDNF EELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENL DEMIALQTKNKLEKNATDNISKLFPAPS-EKSHEETDSTKEEAAKMEKEYGSLKDSTKDD NSNPGGKTDEPKGKTEAYLEAIRKNIEWLKKHDKKGNKE--------------------- ----DYDLSKMRDFINKQADAYVEKGILDKEEAEAIKRIYSSL >XP_011486775.1 secretogranin-3 isoform X1 [Oryzias latipes] ------------------------------------------------------------ ----------------------------------------------------M------- ---------------------------------ASKAVCLFVLSQLLALNVVNPVYAFPT PSAST---------------DADKSVYNQQLTEERPVQQQIAEADSVKAALQSAGGQHPA ASK--ESDQDSDDFTMLKSLADGQKSKE-PSVVPVK-KDDQYVPDESDSTKSRRLADDYD STKKGMDY---GKYQDDPESFRQVDGTPLTAEDIVQKIANKIYEEDDRGVFDRIVSKLLK LGLITESQADTLEYQVAEALQDLITKNAKNNEIDDIESIDQAAGGEQEDQDSD--TGTWE PPKRRYNEKEEDAAE-ADDEDVEDEVEREAEEDVNEAG-DTWE--KGTEDGNEVSPEDGL QDLQYFPNFYRLLKSLNLEKDTQERETLITIMKTLIDFVKMMVKYGTITPEEGVSYLENL DAMIAMQTKNKLGKALGLPDVTA---PS-EKDWDDDDNTKAEAAKMQKEYENLKDSTKEE QPPTETN--QP-GKSEAYLEAIRKNIEWLKKHNKEDGKE--------------------- ----DYDLSKLKDFMDQQLDSYIDKGIIAKEEGDTIKRIYSSL >XP_013225016.1 secretogranin-3 isoform X1 [Columba livia] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----MILSNAAKDS------------FINGETDDTLD-NTWSPSNALERRNELPSEDNF EDLQYFPNFYALLKSLNSETEAKEKETLITIMKTLIDFVKMMVKYGTITPEEAVSYLENL DTMIAEQTKKRLENPSTKARTKL---PA-DKSSEEADSTKEEAAKMEKEYEISKDSTKNE EQKAAGNSEEPRGKAEAYLEAIRKNIEWLKKHNKQGNKE--------------------- ----DYDLPKLRDFIDQQADAYVDEGILDKEEADVIKRIYGSL >XP_013822597.2 PREDICTED: secretogranin-3 isoform X1 [Capra hircus] ------------------------------------------------------------ ----------------------------------------------------M------- ------------------------------------GFLWTGTWIVVLVLHSSPIQAFPK PAGS----------------Q-DKPLHNRELSAERPLNEQIAEAEADKIKKTYPPENKPG ----ESNYSFVDNLNLLKAITEKEKNKKERQSVKISPNDNKLNVEDVDSTKNRRLIDDYD STKSGLDR----KFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDRIVSKLLN LGLITESQAHTLEDEVAEVLQKLISKEANNYE----EELNKPTSKTESQT---------G KIPEKVTPMAAIQNA------------FTNGENDETVS-NTLTLTNGLERRTKTYSEDNF EELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENL DETIALQTKNKLEKNVTDNKSKLFPVPS-EKSHEETDSTKEEAAKMEKEYGTLKDSTKDD DSNPRGKTDEPKGKTEAYLEAIRKNIDWLKKHNIKENKEGQRNHKEVMVSLFTPCIQFKQ HENQDYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >XP_006017995.1 secretogranin-3 isoform X1 [Alligator sinensis] ------------------------------------------------------------ ----------------------------------------------------M------- -------------------------------------VLKLAVVIQVLSLTVGHVHGFPK PEGN----------------R-DKAIHNRQLSVERPLEEQIAEAETDKIRKTVSTENKPE ----FRNYSFADDLNLLQSVAEKERNEKERASIRSSLYEQQLALDDADSTKNRRLVDDYD STKSGLDY----KFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDKIVSKLLN LGLITESQAYTLEDEVAEVLQQLIANEANDGEKES-EALDYPPSRTDSDTE--------E KQEENMTPSNADQDG------------FINGESDDTLD-NTWPSSNALERRNELPSDNNF EDLQYFPNFYALLKSLNSETEAKEKETLITIMKTLIDFVKMMVKYGTITPEEGVSYLENL DEMIALQTKNKLEKPSTDTKNKL---LA-DKSNEETDSTKEEAAKMEKEYETLKDSTKIE EQNTAGNTNQPKGKAEAYLEAIRKNIEWLKKHSKQAPKE--------------------- ----DYDLSKLRDFIDEQADAYVDKGILDKEEADVIKRIYSSL >XP_006261125.1 PREDICTED: secretogranin-3 isoform X1 [Alligator mississippiensis] ------------------------------------------------------------ ----------------------------------------------------M------- -------------------------------------VLKLAVVIQVLSLTLGHVHGFPK PEGN----------------R-DKAIHNRQLSVERPLEEQIAEAETDKIRKTVSTENKPE ----FRNYSFADDLNLLQSVAEKERNEKERASIRSSLYEQQLALDDADSTKNRRLVDDYD STKSGLDY----KFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDKIVSKLLN LGLITESQAYTLEDEVAEVLQQLIANEANDGEKES-EALDYPPSRTDSDTE--------E KQEENMTPSNADQDG------------FINGESDDTLD-NTWPSSNALERRNELPSDNNF EDLQYFPNFYALLKSLNSETEAKEKETLITIMKTLIDFVKMMVKYGTITPEEGVSYLENL DEMIALQTKNKLEKPSIDTKNKL---LA-DKSNEETDSTKEEAAKMEKEYETLKDSTKIE EQNTAGNTNQPKGKAEAYLEAIRKNIEWLKKHSKQGPKE--------------------- ----DYDLSKLRDFIDEQADAYVDKGILDKEEADVIKRIYSSL >XP_015809394.1 PREDICTED: secretogranin-3 isoform X1 [Nothobranchius furzeri] ------------------------------------------------------------ ----------------------------------------------------M------- ---------------------------------ASKYFGLFVLVQLFVLEVDNQTFAFPT PTAST---------------D-DKAVYNRQLTEERPLQEQIAEADSVKAAVQSAESKQPA AFKDAESEQASDDFTMLKSLADGQKSKD-SREVLVK-KEDHHVPDEADSTKSRRLADDYD STKNGMDY---GKYQDDTESFRQVDGTPLTAEDIVQKIANKIYEEDDRGVFDRIISKLLK LGLITENQADSLEYQVAEALQDLITKNAKNNEVEDTENIAQDTGGEQDDQGAD--MDTWE PRKRSYNEEEEEEED-NDDEQIEDDVDRDAEEEMEAAD-NTWD--KDTEEGNEVGQGDGL QDLQYFPNFYQLLRSLNSEKDAQERETLITIMKTLIDFVKMMVKYGTITPEEGVSYLENL DAMIAMQTKNKLGKSLGLPEVGG---PN-GKNMDEDDNTKSETAKMQKEYENLRDSTKEE QPTAESTLDQP-GKSETYLEAIRKNIEWLKKHNKDDGKD--------------------- ----DYDLSKLKDFMDQQVESYIEKGIIAKDEGDTIKRIYGSL >XP_020724875.1 secretogranin-3 isoform X1 [Odocoileus virginianus texanus] ------------------------------------------------------------ ----------------------------------------------------M------- ------------------------------------GFLWTGTWIVVLVLHSSPIQAFPK PAGS----------------R-DKPLHNRELSAERPLNEQIAEAEADKIKKTYPPENKPG ----ESNYSFVDNLNLLKAITEKEKNEKERQSVKISPNDNKLNMDDVDSTKNRRLIDDYD STKSGLDRKFQGKFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDRIVSKLLN LGLITESQAHTLEDEVAEVLQKLISKEANNYE----EELNKPTSKTESQT---------V KIPEKVTPMAAIQDA------------FTSGENDETVS-NTLTLTNGLERRTKTYSEDNF EELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENL DETIALQTKNKLEKNVTDNKSKLFPGPS-EKSHEETDSTKEEAAKMEKEYGTLKDSTKDD DPNPRGKTDEPKGKTEAYLEAIRKNIDWLKKHNKKENKE--------------------- ----DYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >XP_030270157.1 secretogranin-3 isoform X1 [Sparus aurata] ------------------------------------------------------------ ----------------------------------------------------M------- ---------------------------------ASKSVGLFVLFHLVVLNVVSQSSAFPT PTASA---------------D-DKTVYNRQLTEERPLQEQIAEADSVKAAVQSAESQRPA SSKDGESQQDLDDLTVLKSLADGQKSKEAAEEVLLK-KEEQYVPDESDSTKSRRLAEDYD STKNGMDY---GKYPDDTESFRQVDGTPLTAEDIVQKIANKIYEEDDRGVFDRIVSKLLK LGLITDSQADTLEYQVAEALQDLITKNAKNNEIEDIESNNQETRGEQDDQGSDANTDAWD QPRRRYNDGDEEE----DDDEIEDEVDRDAEEEEGDADANTWD--KDAEEGNEVSPEDGL QDLQYFPNFYRLLRSLDSDQDTQERETLITIMKTLIDFVKMMVKYGTITPEEGVSYLENL DAMIAMQTKNKLGKSLGPPDVIG---PN-GKNLDEDDNTKAEAAKMQKEYENLKDSTKEE QPSTESS--QP-GKSETYLEAIRKNIEWLKKHSKEEGKD--------------------- ----DYDLSKLKDFMDQQVDSYIEKGIIAKDEGDTIKRIYSSL >sp|A3KQQ9|SCG3_DANRE Secretogranin-3 OS=Danio rerio OX=7955 GN=scg3 PE=2 SV=1 ------------------------------------------------------------ ----------------------------------------------------M------- ---------------------------------ASKRLG----FVVVLALVCQHINAFPT PAGP----------------D-DK--YNRELTEEKPLEQQIAEADS--IRKTESKPTPPA ---EEETNSEDDDITFLKALAEKSKESNNETPISDS-ANERLGADDTDSTKNRRLADDYD STKNGMDY----KYQDDPESFRQLDGTPLTAQDIVQKIANKIYEEDDRGVFDRIVSKLLK LGLITDSQAETLEYEVAEALQDLITKNAKDNMIGD-RSVDYPVSAAKDTQDEE------D RPSPRFDEEDEVENEGGDDANGDEPQEEESRDDTVRSD-DSWDAVSDGNDRNELNPEDGL QDLQFFPNFYRLLKSLDSEQDKEERETLITIMKTLIDFVKMMVKYGTITPEEGVTYLENL DAMIALQTKNKLGKSLVPLSITP---PT-GKAADDDDNTKTEAAKMQKEYESLKDSTKDV QTAAEIS--HP-GKSESYLEAIRKNIEWLKKHNKEGNKE--------------------- ----DYDLSKLRDFMDQQVDSYIDKGILEKDEGDVIKRIYGSL >XP_040198616.1 secretogranin-3 [Rana temporaria] ------------------------------------------------------------ ----------------------------------------------------M------- ----------------------------------------GVITFLVCTAILYNVQGFPK PDTT----------------Q-DKALHNRELSVERPLEEQI--AEADTVSRGASTETK-- ------NDSLVDDLSFLMSVAEKEKNVKRSGGVISTTNGQKAAPEDGDTTKSLKPVEYFD STKGGLDF----KDEDDPDGLHQLDGTPLTAEDIVQKIAMRIYEENDRGVFDKIVSKLLN LGLITESQAYALEDEVAVVLQQLIANEAKNREKGS-EDVDYPAIKTDANTE--------E KQEGRM----EPQEK------------EVSEQSTNVAD-NDWSPAPNMERRNEMPLEENF EDLQYFPNFYQLIKSLNAENDAKEKETLITIMKTLIDFVKMMVKYGTITPEEGVNYLENL DTMIAVQTKNKLGKNSTYQKNGLL--SA-DKTDEETDSTKEAAANMEKEFEKFKDSTKLE EPKETTDVPTLKGKGEAYLEAIRKNIEWLKKH-KQGGKE--------------------- ----DYDLSKLRDFIDQQADSYVEKGILDQEEANVIKRIYSSL
BMGE Cleaned alignment of selected proteins >NP_033156.1 secretogranin-3 isoform 1 precursor [Mus musculus] GFLWTGSWILVLVLNSGPIQAFPKPEGSDKSLHNRELSAERPLNEQIAEAEADKIKKAFPSESKPSESNYSSVDNLNLLRAITEKETVEKERQSIRSPPFDNQLNVEDADSTKNRKLIDEYDSTKSGLDHKFQDDPDGLHQLDGTPLTAEDIVHKIATRIYEENDRGVFDKIVSKLLNLGLITESQAHTLEDEVAEALQKLISKEANNYEETLDKPTSRTENQDGKIPEKVTPVAAVQDGFTNRENDETVSNTLTLSNGLERRTNPHREDDFEELQYFPNFYALLTSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKLEKNTTDSKSKLFPAPPEKSQEETDSTKEEAAKMEKEYGSLKDSTKDDNSNLGGKTDEATGKTEAYLEAIRKNIEWLKKHNKKGNKEDYDLSKMRDFINQQADAYVEKGILDKEEANAIKRIYSSL >KAB0374934.1 hypothetical protein FD755_013426 [Muntiacus reevesi] GFLWTGTWIVVLVLHSSPIQAFPKPAGSDKPLHNRELSAERPLNEQIAEAEADKIKKTYPPENKPGESNYSFVDNLNLLKAITEKEKNEKERQSVKISPNDNKLNVEDVDSTKNRRLIDDYDSTKSGLDRKFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDRIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANNYEEELNKPTSKTESQTAKIPEKVTPMAAIQDAFTNGENDETVSNTLTLTNGLERRTKTYSEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKLEKNVTDNKSKLFPVPSEKSHEETDSTKEEAAKMEKEYGTLKDSTKDDDSNPRGKTDEPKGKTEAYLEAIRKNIDWLKKHNKKENKEDYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >KAB0343148.1 hypothetical protein FD754_020074 [Muntiacus muntjak] GFLWTGTWIVVLVLHSSPIQAFPKPAGSDKPLHNRELSAERPLNEQIAEAEADKIKKTYPPENKPGESNYSFVDNLNLLKAITEKEKNEKERQSVKISPNDNKLNVEDVDSTKNRRLIDDYDSTKSGLDRKFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDRIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANNYEEELNKPTSKTESQTVKIPEKVTPMAAIQDAFTNAENDETVSNTLTLTNGLERRTKTYSEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKLEKNVTDNKSKLFPVPSEKSHEEIDSTKEEAAKMEKEYGTLKDSTKDDDSNPRGKTDEPKGKTEAYLEAIRKNIDWLKKHNKKENKEDYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >KAF4017458.1 hypothetical protein G4228_009015 [Cervus hanglu yarkandensis] GFLWTGTWIVVLVLHSSPIQAFPKPAGSDKPLHNRELSAERPLNEQIAEAEADKIKKTYPPENKPGESNYSFVDNLNLLKAITEKEKNEKERKSVKISPNDNKLNVEDVDSTKNRRLIDDYDSTKSGLDRKFQDDPDGLHQLDGTPLTAEDIVQKIATRIYKENDRGVFDRIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANNYEEELNKPTSKTESQTVKIPEKVTPMAAIQDAFTNGENDETVSNTLTLTNGLERRTKTYSEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKLEKNVTDNKSKLFPVPSEKSHEETDSTKEEAAKMEKEYGTLKDSTKDDDSNPRGKTDEPKGKTEAYLEAIRKNIDWLKKHNKKENKEDYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >XP_043327918.1 secretogranin-3 isoform X1 [Cervus canadensis] GFLWTGTWIVVLVLHSSPIQAFPKPAGSDKPLHNRELSAERPLNEQIAEAEADKIKKTYPPENKPGESNYSFVDNLNLLKAITEKEKNEKERKSVKISPNDNKLNVEDVDSTKNRRLIDDYDSTKSGLDRKFQDDPDGLHQLDGTPLTAEDIVQKIATRIYKENDRGVFDRIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANYYEEELNKPTSKTESQTVKIPEKVTPMAAIQDAFTNGENDETVSNTLTLTNGLERRTKTYSEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKLEKNVTDNKSKLFPVPSEKSHEETDSTKEEAAKMEKEYGTLKDSTKDDDSNPRGKTDEPKGKTEAYLEAIRKNIDWLKKHNKKENKEDYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >NP_001079046.1 secretogranin-3 [Xenopus laevis] --GPKYVFITAIIGVFVHVQGFPNPSIKDKDVHNRELSEERPLEEQI--AEADTVSRGTSTENQEMLKNDSFADDLGFLMSMGEKDGDVKRSGSTRGSFGSNRGTLDDADSTKNLKLAEYFDTTKSMPDYKYEDDPDGLHQLDGTPLTAEDIVRKIATRIYEENDRGVFDKIVSKLLNLGLITESQAYTLEDEVAEVLQQLIANEAKNREGDLDYADVRSDVYDDKREGKMETLNKNED----RESSETKN--EDSLSTVERRNELSPED---DLQYFPNFNRLVKSLNSENDVKEKKTLLTIMKTLIDFVKMMVKYGTITPEEGVNYLENLDDMIAVQVKNKLGKNFGSHRNAL---PSDKNADESDSTKEEAAKMEKEYELLKDSTKPEPNDAAES--KPKGKAETYLEAIRKNIEWLKEHNKEANKGDNDLSKLKEFVNQQADSYVEKGILDKEEANVIKRIYSSL >NP_037375.2 secretogranin-3 isoform 1 precursor [Homo sapiens] GFLGTGTWILVLVL---PIQAFPKPGGSDKSLHNRELSAERPLNEQIAEAEEDKIKKTYPPENKPGQSNYSFVDNLNLLKAITEKEKIEKERQSIRSSPLDNKLNVEDVDSTKNRKLIDDYDSTKSGLDHKFQDDPDGLHQLDGTPLTAEDIVHKIAARIYEENDRAVFDKIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANNYEEDPNKPTSWTENQAGKIPEKVTPMAAIQDGLAKGENDETVSNTLTLTNGLERRTKTYSEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDEMIALQTKNKLEKNATDNISKLFPAPSEKSHEETDSTKEEAAKMEKEYGSLKDSTKDDNSNPGGKTDEPKGKTEAYLEAIRKNIEWLKKHDKKGNKEDYDLSKMRDFINKQADAYVEKGILDKEEAEAIKRIYSSL >NP_446308.1 secretogranin-3 precursor [Rattus norvegicus] GFLWTGSWILVLVLNSGPIQAFPKPEGSDKSLHNRELSAERPLNEQIAEAEADKIKKTYPSESKPSESNFSSVDNLNLLKAITEKETVEKAKQSIRSSPFDNRLNVDDADSTKNRKLTDEYDSTKSGLDRKVQDDPDGLHQLDGTPLTAEDIVHKIATRIYEENDRGVFDKIVSKLLNLGLITESQAHTLEDEVAEALQKLISKEANNYEEAPEKPTSRTENQDGKIPEKVTPVAATQDGFTNRENDDTVSNTLTLSNGLERRTNPHRDDDFEELQYFPNFYALLTSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKLEKNTTDSKSKLFPAPPEKSHEETDSTKEEAAKMEKEYGSLKDSTKDDNSNLGGKTDEAKGKTEAYLEAIRKNIEWLKKHNKKGNKEDYDLSKMRDFINQQADAYVEKGILDKEEANAIKRIYSSL >XP_040562244.1 secretogranin-3 isoform X1 [Gallus gallus] KNLFHIIIFPVLSLLASRAHGFPKPAG-DKAVHNRQLSVERPLEEQIAEAEADKNRKIGPTENKPEFRNYSFVDDLNLLKSVAERERNEKERESIRTSLYEQQLAIDDADSTKNRRLVDEYDSTKSGLDYKFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDKIVSKLLNLGLITESQAYTLEDEVAEVLQQLIANEAKDREEDFDYPPSRADSDSEKQQEKMTSSKSDQDSFINGEIDDTLDNTWSSSNVLERRNELPSEDDFEDLQYFPNFYALLKSLNSETETKEKETLITIMKTLIDFVKMMVKYGTITPEEGVSYLENLDTMIAVQTKKKLENPSIKTKPKQ---PTDKSSEEADSTKEEAAKMEKEYEISKDSTKNEEQNAAENSEEPRGKAEAYLEAIKKNIEWLKKHNKQGNKEDYDLSKLRDFIDQQADAYVDKGILDKEEADVIKRIYGSL >XP_510407.2 secretogranin-3 isoform X1 [Pan troglodytes] GFLGTSTWILVLVL---PIQAFPKPGGSDKSLHNRELSAERPLNEQIAEAEEDKIKKTYPPENKPGQSNYSFVDNLNLLKAITEKEKIEKERQSIRSSPLDNKLNVEDVDSTKNRKLIDDYDSTKSGLDHKFQDDPDGLHQLDGTPLTAEDIVHKIAARIYEENDRAVFDKIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANNYEEDPNKPTSWTENQAGKIPEKVTPMAAIQDGLAKGENDETVSNTLTLTNGLERRTKTYSEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDEMIALQTKNKLEKNATDNISKLFPAPSEKSHEETDSTKEEAAKMEKEYGSLKDSTKDDNSNPGGKTDEPKGKTEAYLEAIRKNIEWLKKHDKKGNKEDYDLSKMRDFINKQADAYVEKGILDKEEAEAIKRIYSSL >XP_013965059.1 secretogranin-3 isoform X1 [Canis lupus familiaris] GFLWTGTWILVLVLQSSPTQAFPKPGGSDKPLHNRELSAERPLNEQIAEAEADKIKKTYPPENKPGESNYSFVDNLNLLKAITEKEKIEKERQSIRSSPYDNKLNVEDVDSTKNRRLIDDYDSTKSGLNHKFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDKIVSKLLNLGLITESQAHILEDEVAEVLQKLISKEANTYEEEPNKPTSVTESQAGKIPEKVTPMAAIQDGFTNGQNDETVSNTLTLTNGLERRTKIYNEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKLEKNVTDNKSKLFPAPSEKSHEETDSTKEEAAKMEKEYGTLKDSTKDD--NPRGKTDEPKGKTEAYLEAIRKNIEWLKKHNKKGNKEDYDLSKMRDFINQQADAYVEKGILDKEEANAIKRIYSSL >XP_010807648.1 secretogranin-3 isoform X1 [Bos taurus] GFLWTGTWIVVLMLHSSPIQAFPKPAGSDKPLHNRELSAERPLNEQIAEAEADEIKKTYPPENKPGESNYSFVDNLNLLKAITEKEKNEKERQSVKISPNDNKLNVEDVDSTKNRRLIDDYDSTKSGLDRKFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDRIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANNYEEELNKPTSKTESQTGKIPEKVTPMAAIQDAFTNGENDETVSNTLTLTNGLERRTKTYSEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKLEKNVTDNKSKLFAVPSEKSHEETDSTKEEAAKMEKEYGTLKDSTKDDDSNPRGKTDEHKGKTEAYLEAIRKNIDWLKKHNKKENKEDYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >XP_001925946.1 secretogranin-3 [Sus scrofa] GFLWTGTWIVVLVLHSSPIQAFPKPAGSDKPLHNRELTAERPLNEQIAEAEADKIKKTYPPENKPGESNYSFVDNLNLLKAITDKEKNEKERQSVKSSPNDNKLNMEDVDSTKNRRLIDDYDSTKSGLDHKFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDKIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANNY-EELSKPTSRTESQAGNIPEKVTPMAAIQDGLTNGENDETVSNTLTLTNGLERRTKTYSEDDFEELQFFPNFYALLKSIDSEKEVKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKLEKNVTDNKSKLFPAPSEKSHEETDSTKEEAAKMEKEYGTLKDSTKDDDSNPRGKTDEPKGKTEAYLEAIRKNIEWLKKHNKKEDKEDYDLSKMRDFINRQADAYVEKGILDKEEADAIKRIYSSL >NP_001126586.1 secretogranin-3 precursor [Pongo abelii] GFLGTGTWILVLVL---PIQAFPKPGGSDKSLHNRELSAERPLNEQIAEAEEDKIKKTYPPENKPGQSNYSFVDNLNLLKAITEKEKIEKERQSIRSSPFDNKLNVEDVDSTKNRKLIDDYDSTKSGLDHKFQDDPDGLHQLDRTPLTAEDIVHKIAARIYEENDRAVFDKIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANNYEEDPNKPTSWTENQAGKIPEKVTPMAAIQDGLAKGENDETVSNTLTLTNGLERRTKTYSEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDEMIALQTKNKLEKNATDNISKLFPAPSEKSHEETDSTKEEAAKMQKEYGSLKDSTKDDNSNPGGKTDEPKGKTEAYLEAIRKNIEWLKKHDKKGNKEDYDLSKMRDFINKQADAYVEKGILDKEEAEAIKRIYSSL >XP_002717826.1 PREDICTED: secretogranin-3 [Oryctolagus cuniculus] GFFWTGTWILVLVLHSSPTEAFPKPGGGDKSLHNRELSAERPLNEQIAEAEADKIKKANLPENKPGESNYSFVDNLNLLKAITEKEKNEKERQPIRSSPFDNKLNVEDVDSTKNRRLIDDYDSTKSGLDQKFQDDPDGLHQLDGTPLTAEDIVHKIATRIYEENDRGVFDRIVSKLLNLGLITESQAHTLEDEVAEALQQLISKEANNYEEELNKPTSRTENEAGKIPEKVTPMAAIQDDLTNVENDETVSDTLTLTNGLERRTKTYSEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDEMIALQTKNKLEKNATDNKSKLFPAPSEKSHEEADSTKEEAAKMEKEYGTLKDSTKDDSSNLGGKTDEPKGKTEAYLEAIRKNIEWLKKHDKKGNKEDYDLSKMRDFINQQADAYVEKGILDQEEAKAIKRIYSSL >XP_010715658.1 secretogranin-3 [Meleagris gallopavo] AAVGADRDLKAVIELASRAHGFPKPAS-DKAIHNRQLSVERPLEEQIAEAEADKNRKTAPTENKPEFRNYSFVDDLNLLKSVAERERNEKERESIRSSLYEQQLAIDDADSTKNRRLVDDYDSTKSGLDYKFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDKIVSKLLNLGLITESQAYTLEDEVAEVLQQLIANEAKDREEDFDYPPSRADSDSEKQQEKLTSSKSDQDSFINGEIDDTLDNTWSSSNILERRNELPSEDDFEDLQYFPNFYALLKSLNSETETKEKETLITIMKTLIDFVKMMVKYGTITPEEGVSYLENLDTMIAVQTKKKLENPSTKSKPKQ---PADKSSEEADSTKEEAAKMEKEYEISKDSTKNEEQNAAGNSEEPRGKAEAYLEAIKKNIEWLKKHNKQGNKEDYDLSKLRDFIDQQADAYVDKGILDKEEADVIKRIYGSL >XP_003827887.1 secretogranin-3 isoform X1 [Pan paniscus] GFLGTSTWILVLVL---PIQAFPKPGGSDKSLHNRELSAERPLNEQIAEAEEDKIKKTYPPENKPGQSNYSFVDNLNLLKAITEKEKIEKERQSIRSSPLDNKLNVEDVDSTKNRKLIDDYDSTKSGLDHKFQDDPDGLHQLDGTPLTAEDIVHKIAARIYEENDRAVFDKIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANNYEEDPNKPTSWTENQAGKIPEKVTPMAAIQDGLAKGENDETVSNILTLTNGLERRTKTYSEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDEMIALQTKNKLEKNATDNISKLFPAPSEKSHEETDSTKEEAAKMEKEYGSLKDSTKDDNSNPGGKTDEPKGKTEAYLEAIRKNIEWLKKHDKKGNKEDYDLSKMRDFINKQADAYVEKGILDKEEAEAIKRIYSSL >XP_003987187.2 secretogranin-3 isoform X1 [Felis catus] GFLWTGTWILVLVLQSSPVQAFPKPGGSDKPLHNSELSAERPLNEQIAEAEADKIKKTYPPENKPGESNYSFVDNLNLLKAITEKEKVEKERQSIRSSPDDNKLNVEDVDSTKNRRLIDDYDSTKSGLNHKFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDKIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANTYEEEPNKPISVTESQTGKIPEKVTPMAAIQDGFTNGQNDETVSNTLTLTNGLERRTKIYNEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKLEKNVTDNKSKLFPAPSEKSHEETDSTKEEAAKMEKEYGALKDSTKAD--NPRGKTDEPKGKTEAYLEAIRKNIEWLKKHDKKGNKEDYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >XP_004010658.1 secretogranin-3 isoform X2 [Ovis aries] GFLWTGTWIVVLVLHSSPIQAFPKPAGSDKPLHNRELSAERPLNEQIAEAEADKIKKTYPPENKPGESNYSFVDNLNLLKAITEKEKNEKERQSVKISPNDNKLNVEDVDSTKNRRLIDDYDSTKSGLDRKFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDRIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANNYEEELNKPTSKTESHTGKIPEKVTPMAAIQNAFSNGENDETVSNTLTLTNGLERRTKTYSEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKLEKNVTDNKSKLFPVPSEKSHEETDSTKEEAAKMEKEYGTLKDSTKDDDSNPRGKTDEPKGKTEAYLEAIRKNIDWLKKHNKKENKEDYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >XP_030858274.1 secretogranin-3 isoform X1 [Gorilla gorilla gorilla] GFLGTGTWILVLVL---PIQAFPKPGGSDKSLHNRELSAERPLNEQIAEAEEDKIKKTYPPENKPGQSNYSFVDNLNLLKAITEKEKIEKERQSIRSSPLDNKLNVEDVDSTKNRKLIDDYDSTKSGLDHKFQDDPDGLHQLDGTPLTAEDIVHKIAARIYEENDRAVFDKIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANNYEEDPNKPTSWTENQAGKIPEKVTPMAAIQDGLAKGENDETVSNTLTLTNGLERRTKTYSEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDEMIALQTKNKLEKNATDNISKLFPAPSEKSHEETDSTKEEAAKMEKEYGSLKDSTKDDNSNPGGKTDEPKGKTEAYLEAIRKNIEWLKKHDKKGNKEDYDLSKMRDFINKQADAYVEKGILDKEEAEAIKRIYSSL >XP_011486775.1 secretogranin-3 isoform X1 [Oryzias latipes] AVCLFVLSQLLALNVVNPVYAFPTPSASDKSVYNQQLTEERPVQQQIAEADSVKAALQSAGGQHPA-ESDQDSDDFTMLKSLADGQKSKE-PSVVPVK-KDDQYVPDESDSTKSRRLADDYDSTKKGMDYKYQDDPESFRQVDGTPLTAEDIVQKIANKIYEEDDRGVFDRIVSKLLKLGLITESQADTLEYQVAEALQDLITKNAKNNEESIDQAAGGEQEDQEPPKRRYNEKEEDAAEREAEEDVNEAGDTWE--KGTEDGNEVSPEDGLQDLQYFPNFYRLLKSLNLEKDTQERETLITIMKTLIDFVKMMVKYGTITPEEGVSYLENLDAMIAMQTKNKLGKALGLPDVTA---PSEKDWDDDDNTKAEAAKMQKEYENLKDSTKEEQPPTETN--QP-GKSEAYLEAIRKNIEWLKKHNKEDGKEDYDLSKLKDFMDQQLDSYIDKGIIAKEEGDTIKRIYSSL >XP_013225016.1 secretogranin-3 isoform X1 [Columba livia] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MILSNAAKDSFINGETDDTLDNTWSPSNALERRNELPSEDNFEDLQYFPNFYALLKSLNSETEAKEKETLITIMKTLIDFVKMMVKYGTITPEEAVSYLENLDTMIAEQTKKRLENPSTKARTKL---PADKSSEEADSTKEEAAKMEKEYEISKDSTKNEEQKAAGNSEEPRGKAEAYLEAIRKNIEWLKKHNKQGNKEDYDLPKLRDFIDQQADAYVDEGILDKEEADVIKRIYGSL >XP_013822597.2 PREDICTED: secretogranin-3 isoform X1 [Capra hircus] GFLWTGTWIVVLVLHSSPIQAFPKPAGSDKPLHNRELSAERPLNEQIAEAEADKIKKTYPPENKPGESNYSFVDNLNLLKAITEKEKNKKERQSVKISPNDNKLNVEDVDSTKNRRLIDDYDSTKSGLDRKFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDRIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANNYEEELNKPTSKTESQTGKIPEKVTPMAAIQNAFTNGENDETVSNTLTLTNGLERRTKTYSEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKLEKNVTDNKSKLFPVPSEKSHEETDSTKEEAAKMEKEYGTLKDSTKDDDSNPRGKTDEPKGKTEAYLEAIRKNIDWLKKHNIKENKEDYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >XP_006017995.1 secretogranin-3 isoform X1 [Alligator sinensis] -VLKLAVVIQVLSLTVGHVHGFPKPEGNDKAIHNRQLSVERPLEEQIAEAETDKIRKTVSTENKPEFRNYSFADDLNLLQSVAEKERNEKERASIRSSLYEQQLALDDADSTKNRRLVDDYDSTKSGLDYKFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDKIVSKLLNLGLITESQAYTLEDEVAEVLQQLIANEANDGEEALDYPPSRTDSDTEKQEENMTPSNADQDGFINGESDDTLDNTWPSSNALERRNELPSDNNFEDLQYFPNFYALLKSLNSETEAKEKETLITIMKTLIDFVKMMVKYGTITPEEGVSYLENLDEMIALQTKNKLEKPSTDTKNKL---LADKSNEETDSTKEEAAKMEKEYETLKDSTKIEEQNTAGNTNQPKGKAEAYLEAIRKNIEWLKKHSKQAPKEDYDLSKLRDFIDEQADAYVDKGILDKEEADVIKRIYSSL >XP_006261125.1 PREDICTED: secretogranin-3 isoform X1 [Alligator mississippiensis] -VLKLAVVIQVLSLTLGHVHGFPKPEGNDKAIHNRQLSVERPLEEQIAEAETDKIRKTVSTENKPEFRNYSFADDLNLLQSVAEKERNEKERASIRSSLYEQQLALDDADSTKNRRLVDDYDSTKSGLDYKFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDKIVSKLLNLGLITESQAYTLEDEVAEVLQQLIANEANDGEEALDYPPSRTDSDTEKQEENMTPSNADQDGFINGESDDTLDNTWPSSNALERRNELPSDNNFEDLQYFPNFYALLKSLNSETEAKEKETLITIMKTLIDFVKMMVKYGTITPEEGVSYLENLDEMIALQTKNKLEKPSIDTKNKL---LADKSNEETDSTKEEAAKMEKEYETLKDSTKIEEQNTAGNTNQPKGKAEAYLEAIRKNIEWLKKHSKQGPKEDYDLSKLRDFIDEQADAYVDKGILDKEEADVIKRIYSSL >XP_015809394.1 PREDICTED: secretogranin-3 isoform X1 [Nothobranchius furzeri] YFGLFVLVQLFVLEVDNQTFAFPTPTASDKAVYNRQLTEERPLQEQIAEADSVKAAVQSAESKQPAAESEQASDDFTMLKSLADGQKSKD-SREVLVK-KEDHHVPDEADSTKSRRLADDYDSTKNGMDYKYQDDTESFRQVDGTPLTAEDIVQKIANKIYEEDDRGVFDRIISKLLKLGLITENQADSLEYQVAEALQDLITKNAKNNEENIAQDTGGEQDDQEPRKRSYNEEEEEEEDRDAEEEMEAADNTWD--KDTEEGNEVGQGDGLQDLQYFPNFYQLLRSLNSEKDAQERETLITIMKTLIDFVKMMVKYGTITPEEGVSYLENLDAMIAMQTKNKLGKSLGLPEVGG---PNGKNMDEDDNTKSETAKMQKEYENLRDSTKEEQPTAESTLDQP-GKSETYLEAIRKNIEWLKKHNKDDGKDDYDLSKLKDFMDQQVESYIEKGIIAKDEGDTIKRIYGSL >XP_020724875.1 secretogranin-3 isoform X1 [Odocoileus virginianus texanus] GFLWTGTWIVVLVLHSSPIQAFPKPAGSDKPLHNRELSAERPLNEQIAEAEADKIKKTYPPENKPGESNYSFVDNLNLLKAITEKEKNEKERQSVKISPNDNKLNMDDVDSTKNRRLIDDYDSTKSGLDRKFQDDPDGLHQLDGTPLTAEDIVQKIATRIYEENDRGVFDRIVSKLLNLGLITESQAHTLEDEVAEVLQKLISKEANNYEEELNKPTSKTESQTVKIPEKVTPMAAIQDAFTSGENDETVSNTLTLTNGLERRTKTYSEDNFEELQYFPNFYALLKSIDSEKEAKEKETLITIMKTLIDFVKMMVKYGTISPEEGVSYLENLDETIALQTKNKLEKNVTDNKSKLFPGPSEKSHEETDSTKEEAAKMEKEYGTLKDSTKDDDPNPRGKTDEPKGKTEAYLEAIRKNIDWLKKHNKKENKEDYDLSKMRDFINQQADAYVEKGILDKEEADAIKRIYSSL >XP_030270157.1 secretogranin-3 isoform X1 [Sparus aurata] SVGLFVLFHLVVLNVVSQSSAFPTPTASDKTVYNRQLTEERPLQEQIAEADSVKAAVQSAESQRPAGESQQDLDDLTVLKSLADGQKSKEAAEEVLLK-KEEQYVPDESDSTKSRRLAEDYDSTKNGMDYKYPDDTESFRQVDGTPLTAEDIVQKIANKIYEEDDRGVFDRIVSKLLKLGLITDSQADTLEYQVAEALQDLITKNAKNNEESNNQETRGEQDDQDQPRRRYNDGDEEE--RDAEEEEGDADNTWD--KDAEEGNEVSPEDGLQDLQYFPNFYRLLRSLDSDQDTQERETLITIMKTLIDFVKMMVKYGTITPEEGVSYLENLDAMIAMQTKNKLGKSLGPPDVIG---PNGKNLDEDDNTKAEAAKMQKEYENLKDSTKEEQPSTESS--QP-GKSETYLEAIRKNIEWLKKHSKEEGKDDYDLSKLKDFMDQQVDSYIEKGIIAKDEGDTIKRIYSSL >sp|A3KQQ9|SCG3_DANRE Secretogranin-3 OS=Danio rerio OX=7955 GN=scg3 PE=2 SV=1 RLG----FVVVLALVCQHINAFPTPAGPDK--YNRELTEEKPLEQQIAEADS--IRKTESKPTPPAEETNSEDDDITFLKALAEKSKESNNETPISDS-ANERLGADDTDSTKNRRLADDYDSTKNGMDYKYQDDPESFRQLDGTPLTAQDIVQKIANKIYEEDDRGVFDRIVSKLLKLGLITDSQAETLEYEVAEALQDLITKNAKDNMRSVDYPVSAAKDTQDRPSPRFDEEDEVENEEESRDDTVRSDDSWDAVSDGNDRNELNPEDGLQDLQFFPNFYRLLKSLDSEQDKEERETLITIMKTLIDFVKMMVKYGTITPEEGVTYLENLDAMIALQTKNKLGKSLVPLSITP---PTGKAADDDDNTKTEAAKMQKEYESLKDSTKDVQTAAEIS--HP-GKSESYLEAIRKNIEWLKKHNKEGNKEDYDLSKLRDFMDQQVDSYIDKGILEKDEGDVIKRIYGSL >XP_040198616.1 secretogranin-3 [Rana temporaria] ----GVITFLVCTAILYNVQGFPKPDTTDKALHNRELSVERPLEEQI--AEADTVSRGASTETK----NDSLVDDLSFLMSVAEKEKNVKRSGGVISTTNGQKAAPEDGDTTKSLKPVEYFDSTKGGLDFKDEDDPDGLHQLDGTPLTAEDIVQKIAMRIYEENDRGVFDKIVSKLLNLGLITESQAYALEDEVAVVLQQLIANEAKNREEDVDYPAIKTDANTEKQEGRM----EPQEKEVSEQSTNVADNDWSPAPNMERRNEMPLEENFEDLQYFPNFYQLIKSLNAENDAKEKETLITIMKTLIDFVKMMVKYGTITPEEGVNYLENLDTMIAVQTKNKLGKNSTYQKNGLL--SADKTDEETDSTKEAAANMEKEFEKFKDSTKLEEPKETTDVPTLKGKGEAYLEAIRKNIEWLKKH-KQGGKEDYDLSKLRDFIDQQADSYVEKGILDQEEANVIKRIYSSL
PhyML tree of selected proteins (((((NP_001079046_1_secretogranin_3__Xenopus_laevis_:0.36751757,XP_040198616_1_secretogranin_3__Rana_temporaria_:0.2684398):0.13470105,(sp_A3KQQ9_SCG3_DANRE_Secretogranin_3_OS_Danio_rerio_OX_7955_GN_scg3_PE_2_SV_1:0.24510092,(XP_011486775_1_secretogranin_3_isoform_X1__Oryzias_latipes_:0.11303361,(XP_030270157_1_secretogranin_3_isoform_X1__Sparus_aurata_:0.09564376,XP_015809394_1_PREDICTED__secretogranin_3_isoform_X1__Nothobranchius_furzeri_:0.12870916):0.04799036):0.34366253):0.64310618):0.13430657,(((XP_001925946_1_secretogranin_3__Sus_scrofa_:0.02493865,((XP_010807648_1_secretogranin_3_isoform_X1__Bos_taurus_:0.00878628,(XP_004010658_1_secretogranin_3_isoform_X2__Ovis_aries_:0.00435512,XP_013822597_2_PREDICTED__secretogranin_3_isoform_X1__Capra_hircus_:0.00436905):0.00217272):0.00000001,(KAB0374934_1_hypothetical_protein_FD755_013426__Muntiacus_reevesi_:0.00000001,(XP_020724875_1_secretogranin_3_isoform_X1__Odocoileus_virginianus_texanus_:0.01118987,(KAB0343148_1_hypothetical_protein_FD754_020074__Muntiacus_muntjak_:0.004343,(KAF4017458_1_hypothetical_protein_G4228_009015__Cervus_hanglu_yarkandensis_:0.00000001,XP_043327918_1_secretogranin_3_isoform_X1__Cervus_canadensis_:0.00217312):0.00434459):0.00000001):0.00216669):0.00217265):0.01828121):0.01525106,(XP_003987187_2_secretogranin_3_isoform_X1__Felis_catus_:0.01928199,XP_013965059_1_secretogranin_3_isoform_X1__Canis_lupus_familiaris_:0.00671251):0.02175164):0.00852982,((XP_002717826_1_PREDICTED__secretogranin_3__Oryctolagus_cuniculus_:0.05041803,(NP_033156_1_secretogranin_3_isoform_1_precursor__Mus_musculus_:0.01615252,NP_446308_1_secretogranin_3_precursor__Rattus_norvegicus_:0.0296595):0.08307971):0.00583805,(NP_001126586_1_secretogranin_3_precursor__Pongo_abelii_:0.00457951,((NP_037375_2_secretogranin_3_isoform_1_precursor__Homo_sapiens_:0.00000001,XP_030858274_1_secretogranin_3_isoform_X1__Gorilla_gorilla_gorilla_:0.00000001):0.00000001,(XP_003827887_1_secretogranin_3_isoform_X1__Pan_paniscus_:0.00224935,XP_510407_2_secretogranin_3_isoform_X1__Pan_troglodytes_:0.00000001):0.00225633):0.00221041):0.03923591):0.01154128):0.33712974):0.01993593,(XP_006261125_1_PREDICTED__secretogranin_3_isoform_X1__Alligator_mississippiensis_:0.00416265,XP_006017995_1_secretogranin_3_isoform_X1__Alligator_sinensis_:0.00247694):0.06959783):0.06908438,XP_013225016_1_secretogranin_3_isoform_X1__Columba_livia_:0.07295482,(XP_040562244_1_secretogranin_3_isoform_X1__Gallus_gallus_:0.03492632,XP_010715658_1_secretogranin_3__Meleagris_gallopavo_:0.03436078):0.03878877);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)