Click here to access PB0027 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0027 P12107 Collagen type XI alpha 1 chain COL11A1 CO11A1, COLL6, DFNA37, STL2, Collagen alpha-1(XI) chain Homo_sapiens May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils.

DomainsGene Ontology
PF01391 (7_Collagen)
PF01410 (COLFI)
PF02210 (Laminin_G_2)
GO:0005201 (enables) extracellular matrix structural constituent
GO:0008201 (enables) heparin binding
GO:0030020 (enables) extracellular matrix structural constituent conferring tensile strength
GO:0030674 (enables) protein-macromolecule adaptor activity
GO:0046872 (enables) metal ion binding
GO:0050840 (enables) extracellular matrix binding
GO:1904399 (enables) heparan sulfate binding
GO:0001502 (involved in) cartilage condensation
GO:0001503 (involved in) ossification
GO:0002063 (involved in) chondrocyte development
GO:0003007 (involved in) heart morphogenesis
GO:0006029 (involved in) proteoglycan metabolic process
GO:0007601 (involved in) visual perception
GO:0007605 (involved in) sensory perception of sound
GO:0030198 (involved in) extracellular matrix organization
GO:0030199 (involved in) collagen fibril organization
GO:0035987 (involved in) endodermal cell differentiation
GO:0035989 (involved in) tendon development
GO:0042472 (involved in) inner ear morphogenesis
GO:0048704 (involved in) embryonic skeletal system morphogenesis
GO:0048705 (involved in) skeletal system morphogenesis
GO:0050910 (involved in) detection of mechanical stimulus involved in sensory perception of sound
GO:0051216 (involved in) cartilage development
GO:0055010 (involved in) ventricular cardiac muscle tissue morphogenesis
GO:0005615 (is active in) extracellular space
GO:0005576 (located in) extracellular region
GO:0005788 (located in) endoplasmic reticulum lumen
GO:0031012 (located in) extracellular matrix
GO:0005581 (part of) collagen trimer
GO:0005592 (part of) collagen type XI trimer
GO:0062023 (part of) collagen-containing extracellular matrix

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)