Click here to access PB0020 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0020 Q9BRR6 ADP-dependent glucokinase ADPGK 2610017G09Rik, ADP-GK Homo_sapiens Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. GDP and CDP can replace ADP, but with reduced efficiency.

DomainsGene Ontology
PF04587 (ADP_PFK_GK)
GO:0006006 (acts upstream of or within) glucose metabolic process
GO:0016301 (enables) kinase activity
GO:0016740 (enables) transferase activity
GO:0016773 (enables) phosphotransferase activity, alcohol group as acceptor
GO:0043843 (enables) ADP-specific glucokinase activity
GO:0046872 (enables) metal ion binding
GO:0005975 (involved in) carbohydrate metabolic process
GO:0006096 (involved in) glycolytic process
GO:0016310 (involved in) phosphorylation
GO:0061620 (involved in) glycolytic process through glucose-6-phosphate
GO:0005783 (is active in) endoplasmic reticulum
GO:0005576 (located in) extracellular region
GO:0005789 (located in) endoplasmic reticulum membrane
GO:0016020 (located in) membrane

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)