Click here to access PB0017 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0017 P69905 Hemoglobin subunit alpha 1 HBA1 ECYT7, HBA-T3, HBH, METHBA Homo_sapiens Involved in oxygen transport from the lung to the various peripheral tissues.

DomainsGene Ontology
PF00042 (Globin)
GO:0004601 (contributes to) peroxidase activity
GO:0031720 (contributes to) haptoglobin binding
GO:0005344 (enables) oxygen carrier activity
GO:0005506 (enables) iron ion binding
GO:0005515 (enables) protein binding
GO:0019825 (enables) oxygen binding
GO:0020037 (enables) heme binding
GO:0043177 (enables) organic acid binding
GO:0046872 (enables) metal ion binding
GO:0010942 (involved in) positive regulation of cell death
GO:0015671 (involved in) oxygen transport
GO:0042542 (involved in) response to hydrogen peroxide
GO:0042744 (involved in) hydrogen peroxide catabolic process
GO:0098869 (involved in) cellular oxidant detoxification
GO:0005576 (located in) extracellular region
GO:0005615 (located in) extracellular space
GO:0005829 (located in) cytosol
GO:0016020 (located in) membrane
GO:0070062 (located in) extracellular exosome
GO:0071682 (located in) endocytic vesicle lumen
GO:0072562 (located in) blood microparticle
GO:0005833 (part of) hemoglobin complex
GO:0022627 (part of) cytosolic small ribosomal subunit
GO:0031838 (part of) haptoglobin-hemoglobin complex

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)