Click here to access PB0007 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0007 O15335 Chondroadherin CHAD SLRR4A Homo_sapiens Promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin alpha2beta1. May play an important role in the regulation of chondrocyte growth and proliferation.

DomainsGene Ontology
PF00560 (LRR_1)
PF01462 (LRRNT)
PF13855 (3_LRR_8)
GO:0060348 (involved in) bone development
GO:1900155 (involved in) negative regulation of bone trabecula formation
GO:0005615 (is active in) extracellular space
GO:0031012 (is active in) extracellular matrix
GO:0005576 (located in) extracellular region

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)