Click here to access PB0005 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0005 P21810 Biglycan BGN PGI, MRLS, DSPG1, PG-S1, SEMDX, SLRR1A Homo_sapiens May be involved in collagen fiber assembly.

DomainsGene Ontology
PF01462 (LRRNT)
PF13855 (3_LRR_8)
GO:0005201 (enables) extracellular matrix structural constituent
GO:0005515 (enables) protein binding
GO:0005539 (enables) glycosaminoglycan binding
GO:0030021 (enables) extracellular matrix structural constituent conferring compression resistance
GO:0050840 (enables) extracellular matrix binding
GO:0008150 (involved in) biological_process
GO:0019800 (involved in) peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
GO:0060348 (involved in) bone development
GO:0061975 (involved in) articular cartilage development
GO:0005615 (is active in) extracellular space
GO:0005576 (located in) extracellular region
GO:0005796 (located in) Golgi lumen
GO:0009986 (located in) cell surface
GO:0030133 (located in) transport vesicle
GO:0031012 (located in) extracellular matrix
GO:0042383 (located in) sarcolemma
GO:0043202 (located in) lysosomal lumen
GO:0070062 (located in) extracellular exosome
GO:0062023 (part of) collagen-containing extracellular matrix

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)