PB0248

DATABASE

Click here to access PB0248 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0248	P18206	Vinculin	VCL	CMD1W, CMH15, HEL114, MV, MVCL	Homo_sapiens	Actin filament (F-actin)-binding protein involved in cell-matrix adhesion and cell-cell adhesion. Regulates cell-surface E-cadherin expression and potentiates mechanosensing by the E-cadherin complex. May also play important roles in cell morphology and locomotion.

Domains

Gene Ontology

PF01044 (2_Vinculin)

GO:0002162 (enables) dystroglycan binding GO:0003779 (enables) actin binding GO:0005198 (enables) structural molecule activity GO:0005515 (enables) protein binding GO:0008013 (enables) beta-catenin binding GO:0031625 (enables) ubiquitin protein ligase binding GO:0045294 (enables) alpha-catenin binding GO:0045296 (enables) cadherin binding GO:0002009 (involved in) morphogenesis of an epithelium GO:0007155 (involved in) cell adhesion GO:0007160 (involved in) cell-matrix adhesion GO:0030032 (involved in) lamellipodium assembly GO:0030334 (involved in) regulation of cell migration GO:0030336 (involved in) negative regulation of cell migration GO:0034333 (involved in) adherens junction assembly GO:0034394 (involved in) protein localization to cell surface GO:0035633 (involved in) maintenance of blood-brain barrier GO:0043297 (involved in) apical junction assembly GO:0048675 (involved in) axon extension GO:0051893 (involved in) regulation of focal adhesion assembly GO:0070527 (involved in) platelet aggregation GO:0090136 (involved in) epithelial cell-cell adhesion GO:1903140 (involved in) regulation of establishment of endothelial barrier GO:1904702 (involved in) regulation of protein localization to adherens junction GO:0044291 (is active in) cell-cell contact zone GO:0002102 (located in) podosome GO:0005576 (located in) extracellular region GO:0005737 (located in) cytoplasm GO:0005829 (located in) cytosol GO:0005856 (located in) cytoskeleton GO:0005886 (located in) plasma membrane GO:0005911 (located in) cell-cell junction GO:0005912 (located in) adherens junction GO:0005916 (located in) fascia adherens GO:0005925 (located in) focal adhesion GO:0015629 (located in) actin cytoskeleton GO:0016020 (located in) membrane GO:0030055 (located in) cell-substrate junction GO:0034774 (located in) secretory granule lumen GO:0035580 (located in) specific granule lumen GO:0042383 (located in) sarcolemma GO:0043034 (located in) costamere GO:0070062 (located in) extracellular exosome GO:0070161 (located in) anchoring junction GO:1903561 (located in) extracellular vesicle GO:1904813 (located in) ficolin-1-rich granule lumen GO:0032991 (part of) protein-containing complex

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|P18206|VINC_HUMAN Vinculin OS=Homo sapiens OX=9606 GN=VCL PE=1 SV=4 MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKE TVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTS DLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQ ELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAE INEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIR QILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGSSPVAMQKAQQVSQGL DVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAE LCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRA VANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQD LLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFS DTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGKLGATAEKAAAVGTANKSTVEG IQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTK SLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFR EAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEP DFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMM AARQLHDEARKWSSKPGIPAAEVGIGVVAEADAADAAGFPVPPDMEDDYEPELLLMPSNQ PVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAK DIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNIS DEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >sp|P18206-2|VINC_HUMAN Isoform 1 of Vinculin OS=Homo sapiens OX=9606 GN=VCL MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKE TVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTS DLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQ ELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAE INEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIR QILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGSSPVAMQKAQQVSQGL DVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAE LCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRA VANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQD LLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFS DTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGKLGATAEKAAAVGTANKSTVEG IQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTK SLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFR EAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEP DFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMM AARQLHDEARKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQAT EMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >sp|P18206-3|VINC_HUMAN Isoform 3 of Vinculin OS=Homo sapiens OX=9606 GN=VCL MPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRK IIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVN SMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSW DEDAWASKVRVLSGEISKIPNSPWLGVLIGTCLILYLVIFVA
Selected proteins from model organisms >sp|P18206|VINC_HUMAN Vinculin OS=Homo sapiens OX=9606 GN=VCL PE=1 SV=4 MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKE TVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTS DLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQ ELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAE INEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIR QILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGSSPVAMQKAQQVSQGL DVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAE LCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRA VANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQD LLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFS DTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGKLGATAEKAAAVGTANKSTVEG IQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTK SLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFR EAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEP DFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMM AARQLHDEARKWSSKPGIPAAEVGIGVVAEADAADAAGFPVPPDMEDDYEPELLLMPSNQ PVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAK DIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNIS DEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >sp|P18206-2|VINC_HUMAN Isoform 1 of Vinculin OS=Homo sapiens OX=9606 GN=VCL MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKE TVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTS DLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQ ELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAE INEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIR QILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGSSPVAMQKAQQVSQGL DVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAE LCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRA VANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQD LLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFS DTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGKLGATAEKAAAVGTANKSTVEG IQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTK SLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFR EAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEP DFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMM AARQLHDEARKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQAT EMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >sp|P18206-3|VINC_HUMAN Isoform 3 of Vinculin OS=Homo sapiens OX=9606 GN=VCL MPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRK IIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVN SMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSW DEDAWASKVRVLSGEISKIPNSPWLGVLIGTCLILYLVIFVA >NP_033528.3 vinculin [Mus musculus] MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQIL KRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKG ILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMK IFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQA KGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAM QKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAE LCDDPKERDDILRSLGEIAALTSKLGDLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAA VHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAA RGEGESPQARALASQLQDSLKDLKAQMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERA ANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVISAARILLRNPGNQAAYEHFETMKN QWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKRE VENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEP DFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEAR KWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTN LLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRT DAGFTLRWVRKTPWYQ >XP_038949159.1 vinculin isoform X1 [Rattus norvegicus] MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQIL KRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKG ILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMK IFVTTKNSKNQGIEEALKNRNFTVGKMSAEINEIIRVLQLTSWDEDAWASKKDTEAMKRALASIDSKLNQ AKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVA MQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIA ELCDDPKERDDILRSLGEIAALTSKLGDLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKA AVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLAAQLADLA ARGEGESPQARALASQLQDSLKDLKTQMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDER AANFENHSGRLGATAEKAAAVGAANKSTVEGIQASVKTARELTPQVISAARILLRNPGNQAAYEHFETMK NQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKR EVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQE PDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEA RKWSSKPGLPAAQVGIGVVAEADAADAVGFPFPSDMEDDSEPELLLVPANQPVNQPILAAAQSLHREATK WSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNL LQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD AGFTLRWVRKTPWYQ >XP_040558242.1 vinculin isoform X1 [Gallus gallus] MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVSAVQAAVSNLVRVGKETVQTTEDQIL KRDMPPAFIKVENACTKLVRAAQMLQADPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKG ILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMK IFVTTKNTKSQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKKDTEAMKRALALIDSKMNQ AKGWLRDPNAPPGDAGEQAIRQILDEAGKAGELCAGKERREILGTCKTLGQMTDQLADLRARGQGATPMA MQKAQQVSQGLDLLTAKVENAARKLEAMTNSKQAIAKKIDAAQNWLADPNGGSEGEEHIRGIMSEARKVA ELCEEPKERDDILRSLGEISALTAKLSDLRRHGKGDSPEARALAKQIATSLQNLQSKTNRAVANTRPVKA AVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGRRLANVMMGPYRQDLLAKCDRVDQLAAQLADLA ARGEGESPQARAIAAQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPSDTPNREEVFEER AANFENHAARLGATAEKAAAVGTANKTTVEGIQATVKSARELTPQVVSAARILLRNPGNQAAYEHFETMK NQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANMQPQMLVAGATSIARRANRILLVAKR EVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQE PDFPPPPPDLEHLHLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEAINQPMMMAARQLHDEA RKWSSKPVTVINEAAEAGVDIDEEDDADVEFSLPSDIEDDYEPELLLMPTNQPVNQPILAAAQSLHREAT KWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGNKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTN LLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRT DAGFTLRWVRKTPWYQ >XP_020927737.1 vinculin isoform X1 [Sus scrofa] MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQIL KRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKG ILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMK IFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKKDTEAMKRALASIDSKLNQ AKGWLRDPTASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVA MQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIA ELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKA AVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLA ARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDER AANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMK NQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKR EVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQE PDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEA RKWSSKPGNPAAKVGIGVVAEADAADAVGFPVPSDMEDDYEPELLLMPSSQPVNQPILAAAQSLHREATK WSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNL LQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD AGFTLRWVRKTPWYQ >XP_009457029.1 vinculin isoform X1 [Pan troglodytes] MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQIL KRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKG ILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMK IFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKKDTEAMKRALASIDSKLNQ AKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGSSPVA MQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIA ELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKA AVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLA ARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDER AANFENHSGKLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMK NQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKR EVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQE PDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEA RKWSSKPGIPAAEVGIGVVAEADAADAAGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATK WSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNL LQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD AGFTLRWVRKTPWYQ >XP_038347906.1 vinculin isoform X14 [Canis lupus familiaris] MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQIL KRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKG ILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMK IFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKKDTEAMKRALASIDSKLNQ AKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVAELRARGQGASPVA MQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIA ELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKA AVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLA ARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPSREEVFDER AANFEHHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMK NQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKR EVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQE PDFPPPPPDLEQLRLADELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEA RKWSSKPGNRAAEVGIGVVAEADAADAVGFPVPPDMEDDFEPELLLMPSNQPVNQPILAAAQSLHREATK WSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNL LQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD AGFTLRWVRKTPWYQ >NP_001178299.1 vinculin [Bos taurus] MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQIL KRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKG ILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMK IFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQA KGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAM QKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAE LCDDPKERDDILRSLGEISALTSKLGDLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAA VHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAA RGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERA ANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKN QWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKRE VENSEDPKFREAVKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEP DFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEAR KWSSKPGNPAAKVGISVVAEAEAADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKW SSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLL QVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDA GFTLRWVRKTPWYQ >XP_019473128.1 vinculin [Meleagris gallopavo] MLMLVMVGKETVQTTEDQILKRDMPPAFIKVENACTKLVRAAQMLQADPYSVPARDYLIDGSRGILSGTS DLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVM LVNSMNTVKELLPVLISAMKIFVTTKNTKSQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS KDTEAMKRALALIDSKMNQAKGWLRDPNAPPGDAGEQAIRQILDEAGKAGELCAGKERREILGTCKTLGQ MTDQLADLRARGQGATPMAMQKAQQVSQGLDLLTAKVENAARKLEAMTNSKQAIAKKIDAAQNWLADPNG GSEGEEHIRGIMSEARKVAELCEEPKERDDILRSLGEISALTAKLSDLRRHGKGDSPEARALAKQIATSL QNLQSKTNRAVANTRPVKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGRRLANVMMGPYRQD LLAKCDRVDQLAAQLADLAARGEGESPQARAIAAQLQDSLKDLKARMQEAMTQEVSDIFSDTTTPIKLLA VAATAPSDTPNREEVFEERAANFENHAARLGATAEKAAAVGTANKTTVEGIQATVKSARELTPQVVSAAR ILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANMQPQMLV AGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDS GYRILGAVAKVREAFQPQEPDFPPPPPDLEHLHLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKA GEAINQPMMMAARQLHDEARKWSSKPVTVINEAAEAGVDIDEEDDADVEFSLPSDIEDDYEPELLLMPTN QPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGNKRALIQCAKDIAKASDEV TRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLM QSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_002718451.2 PREDICTED: vinculin isoform X1 [Oryctolagus cuniculus] MGAGRGLGRRGGKGGASRRGTNRSGVPGLRGASIGRGDVRGRGAREAGYAEGSPDSVVAAPSQSLRRLPA PPFLVLCCPRFAAPLTAEMPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVS NLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDL LLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLV NSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKD TEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMT DQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKVDAAQNWLADPNGGP EGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQN LQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLL AKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKAQMQEAMTQEVSDVFSDTTTPIKLLAVA ATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARIL LRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAG ATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGY RILGAVAKVREAFQPQEPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGE VINQPMMMAARQLHDEARKWSSKPGIRAAEVGIGGVAEADAADAVGFPVPSDMEDDYEPELLLMPSNQPV NQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRL AKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSV KETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_024109838.1 vinculin isoform X2 [Pongo abelii] MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQIL KRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKG ILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMK IFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQA KGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGSSPVAM QKAQQVSQGLDVLTAKVENAARKLEAMTTSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAE LCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAA VHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAA RGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERA ANFENHSGKLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKN QWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKRE VENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEP DFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEAR KWSSKPGIPAAEVGIGVAAEADAADAAGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKW SSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLL QVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDA GFTLRWVRKTPWYQ >XP_003813044.1 vinculin isoform X2 [Pan paniscus] MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQIL KRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKG ILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMK IFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQA KGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGSSPVAM QKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAE LCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAA VHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAA RGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERA ANFENHSGKLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKN QWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKRE VENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEP DFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEAR KWSSKPGIPAAEVGIGVVAEADAADAAGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKW SSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLL QVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDA GFTLRWVRKTPWYQ >XP_019668863.1 vinculin isoform X1 [Felis catus] MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQIL KRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKG ILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMK IFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKKDTEAMKRALASIDSKLNQ AKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVAELRARGQGASPVA MQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIA ELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKA AVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLA ARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPSREEVFDER AANFEHHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMK NQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKR EVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQE PDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEA RKWSSKRGNPAAEVGIGVVAEADAADAVGFPVPPDMEDDYEPELLLMPSSQPVNQPILAAAQSLHREATK WSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNL LQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD AGFTLRWVRKTPWYQ >XP_027818089.1 vinculin isoform X1 [Ovis aries] MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQIL KRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKG ILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMK IFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQA KGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAM QKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAE LCDDPKERDDILRSLGEISALTSKLGDLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAA VHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAQCDRVDQLTAQLADLAA RGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERA ANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKN QWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKRE VENSEDPKFREAVKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEP DFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEAR KWSSKPGNPAAKVGISVVAEAEAADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKW SSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLL QVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDA GFTLRWVRKTPWYQ >XP_004049661.1 vinculin isoform X2 [Gorilla gorilla gorilla] MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQIL KRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKG ILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMK IFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQA KGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGSSPVAM QKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAE LCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAA VHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAA RGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERA ANFENHSGKLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKN QWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKRE VENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEP DFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEAR KWSSKPGIPAAEVGIGVVAEADAADAAGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKW SSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLL QVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDA GFTLRWVRKTPWYQ >XP_043332427.1 vinculin isoform X2 [Cervus canadensis] MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIK VENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTY TKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAE INEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERRE ILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNG GPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRA VANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAA RGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRL GATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTK SLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVVD AKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEE KDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGNPAAKVGISVVAEAEAADAVGFPVPPDMEDDYEPELLLMPSNQ PVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQC TDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDA GFTLRWVRKTPWYQ >XP_043332426.1 vinculin isoform X1 [Cervus canadensis] MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIK VENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTY TKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAE INEIIRVLQLTSWDEDAWASKKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERR EILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPN GGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNR AVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLA ARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGR LGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDT KSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVV DAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPE EKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGNPAAKVGISVVAEAEAADAVGFPVPPDMEDDYEPELLLMPSN QPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQ CTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD AGFTLRWVRKTPWYQ >KAF4018928.1 hypothetical protein G4228_011024 [Cervus hanglu yarkandensis] MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIK VENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTY TKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAE INEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERRE ILGTCKMLGQMTDQVADLRASRGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPN GGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNR AVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLA ARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGR LGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDT KSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVV DAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPE EKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGNPAAKVGISVVAEAEAADAVGFPVPPDMEDDYEPELLLMPSN QPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQ CTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD AGFTLRWVRKTPWYQ >XP_018094934.1 vinculin isoform X1 [Xenopus laevis] MPVFHTKTIESILEPVAQQISHLVIMHEEGEVDGKAIPELTAPVAAVQAAVSNLVRVGKETVQTTEDQIMKRDMPPAFIK VENACAKLVQAAQMLNADPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVESMEDLVTY TKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKDLLPVLISAMKIFVTTKSSRSQGIEEALKNRNFTVEKMSAE INEIIRVLQLTSWDEDAWASKDTEAMKRALALIDSKINQAKGWLRDPNAPPGDAGEQAVRQILDEAGKVGELCAGTERKD ILGTCRTLGQMTDQVSDLRSRGQGATPIAMQKAQQVSQGLDVLTSKVKNAAHKLEALTNSKQAIGKKIDAAQSWLADPNG GPEGEENIRTILAEAKKIADLCEDPKDKEDILRSLGEIAALTAKLTDLRRQGKGDSPEARALAKQIATSLQNLQTKVNRA VANSRPVKAAVNMDGKVEQAQRWIDNPSVDDRGVGQAAIRSLVAEGRRLANSMTGPFRQDMIAKCDRVEQLAGQLAELAL RGEGDTPLAQAVAAQLQEALKDLKGKMQEAMTQEVSDVFSDTTTPIKLLAVAATSPPDAPNRDEVFEERAANFENHSARL GATAEKAAAVGSANKATVEGIQAAVKSARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTR SLLDASEEAIKKDIDKCKVAMANMQPQMLVAGATSIARRANRILLVAKREMENSEDPKFRDTVKNASDELSKTISPMVME AKAVAGNISNPALQKGFLDSGYRILGAVAKVREAFQPPEPEFPPPPPDLDQLRLSDDAAPPKPPLPEGEVPPPRPPPPDE KDEEFPEQKVGEVVNQPMMVAARQLHDEARKWSSKSPGNYDYPAPQGREAVISEVEQAQEEEEEEASVEFALSSDIEDDY EPELLLVPEGQPVNQPMLAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGNKRALIQCAKDIAKASDEV TKLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREA EAASIKIRTDAGFTLRWARKTPWYQ >XP_005156897.1 vinculin isoform X1 [Danio rerio] MPVFHTKTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTSPVAAVQAAVSNLVRVGKETVQTTEDKIMKRDMPSAFIK VENACAKLVEAAQMLRTDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLITY TKNLGPGMTKMAKMIDERQQELTHQEHRVMLVTSMNTVKELLPVLISAIKIFVTTKCTKSHGVEEALKNRNYTFDKMTAE INEIIRVLQLTSWDEDAWANKDTEAMKRALALIESKMGQAKGWLRDPNALPGDPGEHALRQILDEAGKVGELCAGKERRE ILGTAKTLGQMTDQVSDVRARGQGATPMGMQKAQQVAQGLDILVGKVENAARKLEALTNAKQAIAKRIDNAQSWLADPNG GPEGEENIRALLAEAKRIADLCEDPKERDDILRSIGEIAGLTARLVELRRIGKGDTPEARALAKQIGTALQNLQAKTNRA VANMRPAKAAVTLEGKMEQALRWINNPGVDDHGVGQAAIRGLIAEGRRLASSLPGPYRQELLAKCEQVEQLMMQLADLAA RGEGESPQARAVAAHLLEAIKDLKAKMQEAMTQEVSDVFSDTTTPIKLLAVAATAPLEAPNREEVFEERASNFENHASRL GATAEKAAAVGTANKSTVEGIQAAVKSARDLTPQVTSAARILLKNPGNQAAYEHFDTMKNQWIDNIEKMTSLVDEAIDTK SLLDASEEAIKKDIDKCRVAMANVQPQMLVAGATSIARRANRVLLVAKREVENSEDPKFRELVKAASDELGRTISPMVMA AKGVAGNIQDPGLQKGFLDSGYRILAAVGKVREAFQPQELDFPPPPPDLDQLHVNDDQAPPKPPLPEGEVPPPRPPPPEE KDEEFPEQKAGEMVSEPMMVAARSLHDEARKWSSKPEVPDEGFEAAEAEVDIDDEDEFTDNEDDYEPELLLMSSNQPVNQ PILAAAQSLHQEARKWSSKGNDIIGAAKRMALLMAEMSRLVRGGSGNKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKR IRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISEEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTL RWVRKTPWYQ >XP_020565294.1 vinculin isoform X4 [Oryzias latipes] MPVFHTKTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTVPVAAVQAAVSNLVRVGKETVQTTEDQVMKRDMPPAFIK VENSCSKLVQAAQMLKSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLITY TKNLGPGMTKMSKMIEERQQELTHQEHRQMLVSSMNTIKELLPVLISAIKIFVATKSTRGAGVEEAERNRRFTFEKMSTE INEIIRVLQLTTWDEDAWANKDMEALKRSLALIESRMAQAKSWLKDPHGQPGDSGELALRVILDEAGKVGELCAGKERKD VLATTKALGQMTDQIADLRARGQGPTPGCVQRAGQCSQGLDLLYGKVDSAARRLEALISAKQAIARKLDAAQAWLADPNG GPEGEENIRALLAEAKRIADLCEDPKERDDILRSISEIVGLTTRLAELRKQGKGDSPEARALAKQIGGALLTLQSKTNRA VANMRPAKPAVTLEGKMEQALRWVNNPGVDDRGVGQAAIRGMVGEGRRLAAGLLGPYRQDMIGRCDRTEGLMAALADMAG RGEAEAPHARVTAAQLQDSLKDLRQHMQEVMTQDVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAGNFETHASRL GATAEKAAAVGTANKSTVEGIHATVKHARELTPQVTSAARILLRNPGNKAAYEHFDTMKNQWIDNVERLTGLVDEAIDTK SLLDASEEAIKKDIDKCRVAMANVQPQMLVAGATSIARRANRVLLVAKREVENSEDPRFRDCVKHASDILSHTISPMVMD AKAVAGNIQDKALQKAYLDSCLRILAAVGKVREAFQPQEPDFPPPPPDLDQLHVSDEQAPPKPPLPEGEVPPPRPPPPEE KDEEFPEQKAGEVLSEPMMVAARQLHDEARKWSSKPEDEEAIEEREVDDEDEFTDGEDDYEPELLMMPSNQPVNQPILAA AQSLHQEARKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGNKRALIQCAKDIAKASDEVTRLAKEVAKQCTDRRIRTNL LQVCERIPTISTQLKILSTVKATMLGRTNISEEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRK TPWYQ >XP_030297248.1 vinculin-like isoform X4 [Sparus aurata] MPVFHTKTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTVPVAAVQAAVSNLVRVGKETVQTTEDQVMKRDMPPAFIK VENSSSKLVQASQMLKADPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLITY TKNLGPGMTKMSKMIEERQQELTHQEHRQMLVNSMNTVKELLPVLISAIKIFVTTKSSRGAGVEEAERNRRFIFEKMSAE INEIIRVLQLTTWDEDAWANKDMEALKRSLALIESKMAQAKGWLKDPHGQPGDPGEVALRVILDEAGKVGELCAGRERKD ILATAKALGQMTDQIADLRARGQGPSPGCVQRAGQCSQGLDLLFGKVDCAARRLEALINAKQAIARRLDAAQAWLADPNG GPEGEENIRALLAEAKRIADLCEDPKERDDILRSISEIAGLTARLVELRKQGKGDSPEARALAKQIGAALLTLQSKTNRA VANMRPAKPAVTLEGKMEQALRWANNPGVDDRGVGQAAIRGMVGEGKRLAGGLLGPYRQDMIGRCDRTEALMTSLADMAN RGEAEAPHARATAAQLQDSLKDLRQHMQEVMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNRAEVFEERAGNFEAHAGRL GATAEKAAAVGTANKSTVEGIHAAVKHARELTPQVTSAARILLKNPGNKAAYEHFDTMKNQWIDNVEKLTGLVDEAIDTK SLLDASEEAIKKDIDKCRVAMANVQPQMLVAGATSIARRANRVLLVAKREVENSEDPRFRDTVKHASDILSHTISPMVMD AKAVAGNIQDKALQKAYLDSCLRILAAVGKVREAFQPQEPDFPPPPPDLDQLHVSDEQAPPKPPLPEGEVPPPRPPPPEE KDEEFPEQKVGEVLSEPMMVAARQLHDEARKWSSKPEDEEAVEEREVDDEDEFTDGEDDYEPELLMMPSNQPVNQPILAA AQALHQEARKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGNKRALIQCAKDIAKASDEVTRLAKEVAKQCTDRRIRTNL LQVCERIPTISTQLKILSTVKATMLGRTNISEEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRK TPWYQ >OWK07868.1 VCL [Cervus elaphus hippelaphus] MLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAK MIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSW DEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPNASPGKERREILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQV SQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRKGD SPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMG PYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATA PPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHF ETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSE DPKFREAVKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEPDFPPPPPDLEQLRLT DELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGNPAAKVGISVVAEAEAAD AVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRAL IQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETV REAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_015799676.1 PREDICTED: vinculin-like isoform X4 [Nothobranchius furzeri] MMPVFHTKTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLSVPVAAVQAAVSNLVRVGKETVQTTEDQLMKRDMPPAFI KVENSSSKLVQAAQMLKADPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLIT YTKNLGPGMTKMSKMIEERQQELTHQEHRQMLINSMNTVKELLPVLISAIKIFVATKSSRGAGVEEAERNRKFTFEKISA EMHEIIRVLQLTTWDEDTWANKDMEALKRSLALIESKMAQAKSWLKDPHGQPGDPGEVALRVILDEAGKVGELCAGKERK DILATTKALGQMSDQIADLRVRGQGPTPGCVQRAGQCSQGLDLLFGKVDSAARRLEALINAKQAIARRLDAAQAWLADPN GGAEGEENIRALLAEAKRIADLCEDPKERDDILRSINEIAGLAARLVELRKQGKGDSPEARALAKQIGAALLNLQSKTNR AVANMRPAKPAVTLEGKMEQALRWVNNPGVDDRGVGQAAIRGMVGEGKRLAGGLLGPYRQDMIGRCDRTEALMTSLADMA NRGEAEAPHARATAAQLQDTLKDLRQHMQEVMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFEERAGNFETHAGR LGATAEKAAAVGTANKSTVEGIHAAVKHARELTPQVTSAARILLKNPGNKAAYEHFDTMKNQWIDNVERMTGLVDEAIDT KSLLDASEEAIKKDIDKCRVAMANVQPQMLVAGATSIARRANRVLLVAKKEVENSEDPRFRDTVKHASDILSHTISPMVM DAKAVAGNIQDKALQKAYLDSCLRILAAVGKVREAFQPQEPDFPPPPPDLDQLHVNDEQAPPKPPLPEGEVPPPRPPPPE EKDEEFPEQKASEVLSEPMMVAARQLHDEASKWSSKPEDEEAVEEREVDDEDEFTDGEDDYEPELLMMPSNQPVNQPILA AAQSLHQEARKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGNKRALIQCAKDIAKASDEVTRLAKEVAKQCTDRRIRTN LLQVCERIPTISTQLKILSTVKATMLGRTNISEEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVR KTPWYQ >XP_021139948.1 vinculin [Columba livia] MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLIYSEILNLKYDFFLPQVGKETVQTTEDQIL KRDMPPAFIKVENACTKLVQAAQMLQADPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKG ILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMK IFVTTKNSKSQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALALIDSKMNQA KGWLRDPNAPPGDAGEQAIRQILDEAGKAGELCAGKERREILGTCKTLGQITDQLSDLRARGQGATPMAM QKAQQVSQGLDLLTAKVENAARKLEAMTNSKQAIAKKIDAAQNWLADPNGGSEGEEHIRGILAEARKVAE LCEEPKERDDILRSLGEISALTAKLSDLRRHGKGDSPEARTLAKQIATALQNLQSKTNRAVANTRPVKAA VHLEGKIEQAQRWIDNPTVADRGVGQAAIRGLVAEGRRLANVMMGPYRQDLLAKCDRVDQLAAQLADLAA RGEGESPQARAIAAQLQDSLKDLKTRMQEAMTQEVSDIFSDTTTPIKLLAVAATAPSDAPNREEVFEERA ANFENHAARLGATAEKAAAVGTANKTTVEGIQATVKSARELTPQVVSAARILLRNPGNQAAYEHFETMKN QWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANMQPQMLVAGATSIARRANRILLVAKRE VENSEDPKFREAVKVASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEP DFPPPPPDLEQLHLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEAINQPMMMAARQLHDEAR KWSSKPDVTVINEAAESVDIDDEDDADVEFTLPSDTEDDYEPELLLMPTNQPVNQPILAAAQSLHREATK WSSKGNDIIAAAKRMALLMAEMSRLVRGGSGNKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNL LQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD AGFTLRWVRKTPWYQ >XP_005699280.1 PREDICTED: vinculin isoform X1 [Capra hircus] MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQIL KRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKG ILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMK IFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQA KGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAM QKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAE LCDDPKERDDILRSLGEISALTSKLGDLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAA VHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAQCDRVDQLTAQLADLAA RGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERA ANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKN QWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKRE VENSEDPKFREAVKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEP DFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEAR KWSSKPGNPAAKVGISVVAEAEAADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKW SSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLL QVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDA GFTLRWVRKTPWYQ >XP_025068505.1 vinculin isoform X1 [Alligator sinensis] MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQIL KRDMPPAFIKVENACTKLVQAAQMLQADPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKG ILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMK IFVTTKNCKSQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKKDTEAMKRALALIDSKMNQ AKGWLRDPNAPAGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGATPVA MQKAQQVSQGLDLLTAKVENAARKLEAMTNSKQAIAKKIDAAQNWLVDPNGGSEGEEHIRGIMAEARKIA ELCEEPKERDDILRSLGEISALTAKLSDLRRHGKGDSPEARALAKQIATSLQNLQSKTNKVVANTRPVKA AVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGRRLANVMMEPYRQDLLARCDRVEQLAAQLADLA ARGEGESPQARAIAAQLQDSLKDLKTRMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNRDEVFGER AANFENHAARLGATAEKAAAVGTANKTTVEGIQATVKSARELTPQVVSAARILLRNPGNQAAYEHFETMK NQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKR EVENSEDPKFREAVKAASDDLSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQE PDFPPPPPDLEQLHLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEA RKWSSKPDVTEVNEATEAGVDIDEEDDADDAEFTLPSDIEDDYEPELLLIPSNQPVNQPILAAAQSLHRE ATKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIR TNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKI RTDAGFTLRWVRKTPWYQ >XP_006273854.1 PREDICTED: vinculin isoform X2 [Alligator mississippiensis] MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQIL KRDMPPAFIKVENACTKLVQAAQMLQADPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKG ILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMK IFVTTKNCKSQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALALIDSKMNQA KGWLRDPNAPAGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGPTPMAM QKAQQVSQGLDLLTAKVENAARKLEAMTNSKQAIAKKIDAAQNWLADPNGGSEGEEHIRGIMAEARKIAE LCEEPKERDDILRSLGEISALTAKLSDLRRHGKGDSPEARALAKQIATSLQNLQSKTNKVVANTRPVKAA VHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGRRLANVMMEPYRQDLLAKCDRVEQLAVQLADLAA RGEGESPQARAIAAQLQDSLKDLKTRMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNRDEVFGERA ANFENHAARLGATAEKAAAVGTANKTTVEGIQATVKSARELTPQVVSAARILLRNPGNQAAYEHFETMKN QWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKRE VENSEDPKFREAVKAASDDLSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQEP DFPPPPPDLEQLHLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEAR KWSSKPDVTEVNEATEVGVDIDEEDDADDAEFTLPSDIEDDYEPELLLIPSNQPVNQPILAAAQSLHREA TKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRT NLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIR TDAGFTLRWVRKTPWYQ >XP_020770146.1 vinculin isoform X1 [Odocoileus virginianus texanus] MPVFHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQIL KRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKG ILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMK IFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKKDTEAMKRALASIDSKLNQ AKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVA MQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIA ELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKA AVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLA ARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDER AANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMK NQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKR EVENSEDPKFREAVKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPQE PDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEA RKWSSKPGNPAAKVGISVVAEAEAADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATK WSSKGNDIIAAAKRMALLMAEMSRLVRGGSGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNL LQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD AGFTLRWVRKTPWYQ >XP_040176600.1 vinculin isoform X1 [Rana temporaria] MPVFHTKTIESILEPVAQQISHLVIMHEEGEVDGKAIPELTTPVAAVQSAVSNLVRVGKETVQTTDDQMM KRDMPPAFIKVENACAKLVQAAQMLHADPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKG ILEYLAVAEVVESMEDLVTYTKNLGPGMTKMAKMIDDRQQELTHQEHRVMLVNSMNTVKDLLPVLISAMK IFVTTKSSRSQGVEEALKNRNFTVDKMSAEINEIIRVLQLTSWDEDAWASKKDTEAMKRALAHIGSKMNQ AKGWLRDPNAPPGDAGEQAVRQILDEAGKVGELCAGKERRDILGTCKALGQITDQVADLRARGQGATPTA MQKAQQVSQGLDLLTAKVENAARKLEALTNSKQAIGKKIDTAQSWLADPNGGPEGEETIREILAEAKRIA ELCEDPKDREDILRSLGEIAACTAKLSDLRRQGKGDTPEARALAKQIGTSLQNLQTKVNRAVANSRPVKA AVNMEGKVEQAQRWIDNPSVDDRGVGQAAIRGMVAEGRRLANSMIGPYRQDMMARCDCVEQLAGQLAELA ARGEGDTPHARAVAAQLQDALKDLKAKMQEAMTQEVSDVFSDTTTPIKLLAVAATSPPDAPNREEMFDDR AANFESHAARLGATAEKAAAAGSANKATVEGIQATVKTARELTPQVVSAARILLRNPGNQAAYEHFETMK NQWIDNVEKMTGLVDEAIDTRALLDASEEAIKKDIDKCKVAMANMQPQMLVAGATSIARRANRIMLVAKR EVENSEDPKFREAVKNASDDLSKTISPMVLEAKAVAGNISDPALQKGFLDSGFRILGAVAKVREAFQPPE PDFPPPPPDLEHLRLTDEAAPPKPPLPEGEIPPPRPPPPDEKDEEFPEEKVGEVNEPMMVAARQLHEEAR KWSSKSPGSPAPATPQGTEAVVSEVEQEREEEEEASVEFVLSDVEDDYEPELLLVPEGQPVNQPMLAAAQ SLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGGSGNKRALIQCAKDIAKASDEVTKLAKEVAKQCT DKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEA ASIKIRTDAGITLRWARKTPWYQ >XP_039272784.1 vinculin-like isoform X1 [Styela clava] MPVFHTKTIQMILEPVAEQVSTLVLIHEQGKDGNQMPDLINPILTVKAAVSNLVKVGKDQIKDTKDEILKLDTPPALEKV ETSADMLVQASQLLSIDQKRETAEMTPEGMEGRKKLIAGSRGILQGTSDLLLVFDEAEVRRICKVCRNVRDYLNQSSIVA GMEDLVVFVKSLTPGTTTLARMIGDRCKDLTNQNHVAALTEEMDQVKAYIPGLISSLKAFVQTVDKPGKAQEAAIGNREY YTTQISERITEIIRLLQLVSTDDANTDPLNVLQLKQTQQKMARKMQPAKNWLNNPNAPAGGPGELALREILDGAKEIGNQ AGGPLGDKILGTTAHLGTLTDQLSDLRANGKGNSAEAKQIATQINGELDQLMEDVDDAIEAMDKLAMAHSGMVKTMPAAR EWLANLSAKPKEGAEHVHNVTKAGREIAMGLGSCKDRDDIIQLCDEIDDMMQKLEEFRTLGLGDTPEAVALSKSIADKLT ALNAKVAKALASKKSVATLDSKMEEIARWLDNPGVKDGGRGLARSTKSLLGDARQIAARISDPNARFALLKNVAECDRLL KDLEHLIQTGRGDSKEAKEIAKKLQKKLEEVKKQMKDALVRAVADEFADTTTSLKQLHSAAIAPLDTLNREENFEGKALT FQSQSTRLADLARQAVGASDLVSQEKVDEVKKKAVRIEGLTPQVINAGRIVLSNPENKTSLEHFETLKQDWTRNMDELTD MVDDSVDFATFMDASEESMRREHEACVKAVKLDKPADALPLAGNISRRAHRILMTGKREMQNTDDPQYVEQLRKNLNAIQ QQLDPTLKSARTYAGAPANRKNQNDFIDNEDKLIQAVSNLQKTVKAEIIEKEKQRKALEEPPPVPPMPVCQTELPPPVPP PPEEEFPEVESNQPIMVAAKELHEEAKKWESTGNNIIAAAKKMALLMAKMSRLVDGEEGSRSELIQCAKDIAKASNDVTK YAKEVATQCTDKRIKTDMMKTLDRLPTISTQLRILSTVKATTLGNPSQEKEEDAEQATEMLVHNAQNLMQSVKETVRYAE AASIRIRTDAGLTMRWVRKDN >CAE1284850.1 VCL [Sepia pharaonis] MPVFHTKTIEGILEPVAQQVSKLVILHEEAEDGNAMPDLARPVQAVKLAVDNLVKVGYDTINSSEDQILKQDMPPALHRV EDASVLLLEASDMLRDDPFSAPARKKLIEGSRGILQGTSSLLLAFDESEVRKIIRVCKNVLEYLAITEVVDKMEDLVTYV KNLSPVLTKIIKEVDAREKELTHQVHRDMLIRSLDQVKNLTPVLISGVKIFITAKETSTGFAEAQNNRDFVVRKMSDEIH EIIRVLQLTTYDEEEWDADDLTVMKKAQCAIEGKLQQAADWLQDPAALVGSAGDKALHQILEDARKIAERCSNPNERDSI LRTVGDIESMANTLAELRQQGKGSSPQAMSLAREIQNKLRDLTQLTQNGIVNTERSGVRKPAPTVSGKVEQAQRWLVNPG LDDKGLGEQATRMVVAEGRKVAESLTGPQRAELLRLCDETEILTNQLSDLIRRGQGNSPQAQACARHLSEKLHALKNKIG EGLVNQVAEDFIDMTTPLKQLSDAAMAPLGVPGREQNFDEKARNFLTQSSKLSDTANMVATAGGCCNKKTVEAIFATSAQ ANDLSPQVVNAAKIVLINPENQAAVDHFDLLKKQWTENMERLRTLVDEATDTEAFIRATEVGIKKDTEKVEDGIRAVSPQ MVVANASNIARRANRVLQVAQQEAENSEDPAFVEKVNQSSDILKSSITPMVQQAKAVSMNPKDPAAANNWRKENNNLIAA VGQVRESVTVSPKTSDLYGQPFPQPPDMSQLHISDAPPRPPLPHETVPPRPPPPETDDEDESAFPMPQANQPIMMAAHDL HMETKQWSSKDNEIIVAAKKMALLLAKLSHLVSCESTCKWIWCTAHKM >XP_030848750.1 vinculin isoform X6 [Strongylocentrotus purpuratus] MPVFHTKTIEAILDPVAQQVSQLVILHEEAQDGNAMPDLSRPVMAVSAAVQNLVKVGRDTANSTDDKILKQEMPPAFQGV EQSATKLYEAAMMLKEDPYSSPARKMLIDGARGILSGTSDLLLCFDQSEVRKIVRVAKGVLEYLAVSEVVESMEDLVTFV KNLSPGMANLANKVTGRSKELTHTAHANGLVNHTENLKRTTPILVSSIKIFVTTLQKGGAGRDEAQQNRNFIIGRMSHDV NEIIRILQLTSADDDDWSMDDLTIMKKSLLNITNQMNMAQTWLANSNAEPGGLGEKAVRDILRDARRVADRLEGPQREHL LATINEIEVMMNELCALRAKGQGNSPRALQLAKQIAEKLGYLHQEVDFAVKDAVKSGVTRTAYTLAGKVEQAQKWLRNPA QDDKGVGRRAVAGIVAQGRKVAQNLSEPERGELLRLCDEVESLSQQITDLVNRGQGNSPQCLDAARRLAERLPSLQKMIE NALAKEVAEVFMDTTTPLKELERAAKAPADDPNRQQTYTSKATIFLTHANKISDTAKLVAEAGASNDRPLVEELNNKAQE VKDLAPQVVAAGKVLLLNPGEQTAVSHFDELKREYMGKVETLTDLVDQAVDTVEFVKASEEAIKRDSEKVAQAIQQNDPN VIAAKASSIARRAQRVAVVASKEAANSEDPKFVQDVSRAANQLSGDIPPSVTAAKGVTLNPADRNAQDKWFTANKQVQSD VGDVRQALTVNQEPIMPPPPDMSRLQLEEAAPPRPPLPGDVPPPRPPPPEDTSLPLPEQGSHQPIMQAAYDLHVETEQWS SKDNDLIAAAKRMAQLMAAMSKHVSGEKTSKKELIEIAKKIAQASLEVVRLAGEIAAQCTDKRMKNNLLQVCERIPTIST QLKILSTVKAVMLGSQESEEDMEATEMLVGNAQNLMKAVKETVRAAKAASIKIRTDAGYKMRWVRQRPWYQ >XP_031557163.1 vinculin-like [Actinia tenebrosa] MPVFHTKTIESILDPVAQQVSQLVIFHEEGEDGRAMPDLSAPIKAVGAAVANLVKVGQQTAANSKDKILRQEMPLAFTRV EESSTFLVEAAKILKNDPYSSVARKKLIDGARGILSGTSALLLTLDEAEVRRILHVCKSLLEYFPVAEMVEEMTDLVTFV TNLTPGTTSLAKQVEERAEELTHHEHRDILKSCIGKIKHLVPLLISAMKAFVKTPLGAGRAEAQENRNFIITKICAEITE IMRVLQLTSTEENKGDDPLYDMKKAVSVFDSKFDKAREWIGEPTCDAGGLGDQAVRECIQQGRLMGSVCQDPQKNKIQRC CDDLDRLMSELETLRSQGKGTTPRGLELSREVDKQLGVLRNLMDEAIHHQGISGIKKPANTFVGKMEQAQQWLANPSGDH TGLGEKAIRECINDARKIADKSSGPERMELLKLCNEVERLTDELADLKRRGLGNSPQAYALANKLSNKLDELHRQTQRAI ANQVAQNFVDPTGQIKQLERAAKAPRGTPNREADFETKAGNFEHQANEMADTAFRFANNSSTTRKKSLEDIRKTAQYMKE LTPQVSHAAKVLLDNPDEPAAGEHFEKLKDEWVQETTKLANSIDSTADTLQLIEACEEAINRDVLACDNALSQENPQLVV AKTSNIARMAQRIAKLVNAEAENTEDPEFRAKLEQMSRNIQDVIAPLAIEAKSVVSNIKDKQGHERLRAAMRRVQRNVGE VRKVFIDRATQSDDEDFPPPPPPPPPEMEDLSLHERERAPPRPPLPREMTTSAPPRPPPPAMEPKIDMNLQSMLESPPED NRMAMAASNLHKEILKWEEQGNDMIQAAKRMAVLFAKMSKFMRDEEEGEPHSKKELIQLAKEIATASKEIVKFGNRACQK CSDKRLKASMQQTIDRIPTISTQLKIVSTVKATMIGSQELEEDREATETLVGCAENLMSAVRQTVRETEAASVKMRTDAG LVMHWKKKQY >XP_026301464.1 vinculin isoform X3 [Apis mellifera] MPVFHTKTIESILEPVAQQVSRLVILHEEAEDGNAMPDLGKPVQAVSMAVANLVKVGKETINSSDDALLKQDMPAALQRV EGASRLLEEASAMLKQDPYSGPARKKLIEGSRGILQGTSSLLLCFDESEVRKIIRECKRVLDYLAVTEVIETMEDLVHFL KNLSPCLSKVSKEVSAREKELTHQVHREILVRCLEQVKTLAPILICSMKIFIHIISQGGKGAEEAAENRNYLSGRMSDEL NEIIRVLQLTTYDEEEWDADQLTVLKKAQSAIESRIRAAYDWLDDGFALRGGLGEKSLRQIVEQAQRLAERYLPPSQAES LQKLTSQIVTMTNALCELRQNEKGSTPQAEALARSIKEKTNELRSSIASAIIAADKSGTTQTAHTVAGRLEQANKWLLNP QHDDKGLGQRAIALIIHEGKKVAEGLPGIHKAEILQLCDEVDNLSHQLGDLCAHGQGNTPRAQEIARQLSHKLYELKNRI QQAVVSRVVEDFIDITTPLKQFTDAVLTPEGSLGRDQNFNDKTHALQTFSNRATKTAKMVAAGGSGGNKKLAEALTTSAS QVESLTPQLINAGRIRMTYPDSKAADEHFENLRQQYADTIQRVRALCDEATDSGDFIRTSEEQMQKHSFLCEEAIAKSHP QKMVDNTAAIARLANRVILVAKQESDNSEDTAFIQRVNQATDILQNSVAPMVQDAKLVAININDNNAVSHWRESNRTLLS NVGQVRKAIVLQPDVISPPEVSQLHLNDEVVPPRPPLPGGDIPPPRPPPPETDDEDEMFMHAPQPNQPIMMAAHGLHQEV RQWSSKDNEIIAAAKKMAILMGRLSGLVRGEGGNKRDLIACAKAIAEASQEVTRLAKELARECTDKRIRTNLLQVCERIP TIGTQLKILSTVKATMLGAQETLPTWEELMLYGTEEDQEATDMLVGNAQNLMQSVKETVRAAECASIKIRTASGMKLRWV RRQPWYQY >NP_001284813.1 vinculin, isoform B [Drosophila melanogaster] MPVFHTKTIESILDPVAQQVSRLVILHEEAEDGNAMPDLSRPVQVVSAAVANLVKVGRDTINSSDDKILRQDMPSALHRV EGASQLLEEASDMLRSDPYSGPARKKLIEGSRGILQGTSSLLLCFDESEVRKIIQECKRVLDYLAVAEVINTMEQLVQFL KDLSPCLSKVHREVGAREKELTHQVHSEILVRCLEQVKTLAPILICSMKVYIHIVEQQGRGAEEAAENRNYLAARMSDEL QEIIRVLQLTTYDEDTSELDNLTVLKKLSNAISNKMEQANEWLSNPYALRGGVGEKALRQVIDNATEISERCLPQDSYPI RKLADEVTAMANTLCELRQEGKGQSPQAESLVRGIRDRMGELKSLVHQAVLGVDKAGVQQTAHTIQGRLEQAVKWLQHPE INDGGLGERAINLIVEEGRKVAEGCPGHQKAEIQQLCDEVERLKRQAAGSGPAAKQAAKQLTQKLYELKAAIQNALVNRI VQDFMDVSTPLKQFTEAVLQPEGTPGREQNFNQKSNNLQAFSDRASKTSRMVAAGGACGNKKIAEILLSSAAQVDSLTPQ LISAGRIRMNYPGSKAADEHLQNLKQQYADTVLRMRTLCDQATDPADFIKTSEEHMQVYAKLCEDAIHARQPQKMVDNTS NIARLINRVLLVAKQEADNSEDPVFTERLNAAANRLERSLPAMVGDAKLVATNIADPAAAAAWKNSFQRLLGDVREVRDA IAPPQPPPLPTSLPPPIPELSALHLSNQNAERAPPRPPLPREGLAPVRPPPPETDDEDEGVFRTMPHANQPILIAARGLH QEVRQWSSKDNEIIAAAKRMAILMARLSELVLSDSRGSKRELIATAKKIAEASEDVTRLAKELARQCTDRRIRTNLLQVC ERIPTIGTQLKILSTVKATMLGAQGSDEDREATEMLVGNAQNLMQSVKETVRAAEGASIKIRSDQTSNRLQWVRRQPWYQ Y >XP_038053446.1 vinculin-like isoform X5 [Patiria miniata] MPTTSYRTKTIHSILDPVAQQVGHLVILHEQAEDGNAMTDLTSPIKIVDQAVSNLVAVGKQTASTSKDEILRREMPPTFT QVERSSGLLVEASALLKADPYSVPARKKLIEGARGILQGTSDLLFVFDESEVRKIVKICEGVLQLLAVSEVVDTMQDILT FVQALTPGVTNMNSQVSARREELINASHAAQLAQHSEQFQKLIPLLVSSMKIYVTILEQGKPGKQEAWENRTYVASKMIY HIQEIIRVLQAVDDDSFRVDNVTGLRAAQNHIKNNMDKAMGWLADPNALAGGMGEKAVRRILEDAKKVAGGLDGPKKAEI EQAIDEITAMVNELSDLRAKGLGNSPRALELAHALGGEHGKLANLERQINAAIAEILKSSMGKMAYTAGGKLAQAKEWLS NPGADDKGVGYRAIKDIISTGRQIAGTCDDLGQRNDLLRLCNEAESLNDHLRDLCKKGQGNTPQAEATAKKLSEKLGQLN DKMTEIVMGQVSSDFLDPMSAVNKMYEAALAPEGAPHREANFTSKAQIFLESSNKAADTAARFAGIADADRDTVDQIHRL SNQVKELTPQVVSAARIVLMNPNNKVAAAHLDVMKNDWEGAMKELDAKLTSSLDVPAFMKASEESMKKQTELAVAAVHQR NPQTYASCISNIALRGKNMVKVAKREAENSEDPEFQHKVDSASDQVNNCIPPTVTTGKQLMQDMANPDKMANWQDANSKL LDSVGNVRQAFVMSQPPTDAMSSLSLENAPPRPPLPQGEVPPPRPPPPEEETEAHFHEAPPSNQPIMKAAYDLHLETQKW SSQGNDLVAAAKKMAILMAQMSKHVRGEGGSKKDFIMCARMIAKQSGEVTRLANIIADQCTDKRIRLNMKQVIERIPTFS TQLKILTTVKATMLGAQDPEKDEEATEMLIGNAQNLMQAVKESVRASEAASIKIRTDAGLKLRWVRRNPYAY >NP_741437.1 Vinculin [Caenorhabditis elegans] MPVFHTKTIENILEPVAQQVSRLVILHEEANDGNAMPDLTGPVGMVSRAVGNLIQVGYDTCDHSDDRILQQDMPPALQRV EGSSKLLEESSYSLKHDPYSVPARKKLIDGARGILQGTSALLLCFDESEVRKIIRVCRKANDYVAVSEVIESMADLQQFV KDISPVLHDVTNDVNLRQQELTHQVHREILIRCMDSIKVIAPILICSMKTSIELGTPHPRQGHAEAIANRNFMSQRMTEE MNEIIRVLQLTTYDEDEWDADNVTVMRKALSAAKSLLTAALDWLADPHARSGAVGEKAIRRICEYADRISARALPEDAQS IKRSIFEITSFTDELCNLRNNGQPDRENLAAQTARRLKDLVGSQNSSGLMGDALQNAQRHGGANPAHTAAGRLEQALRWL DNPGLDDGGLGLQALRLLTADARKLADRLNPQDRNRLLGLCSDIDRLAAQLADLERRGLGNSPEAHQIRNQLKNALRDLG DFMRRVLTDRVVDDFADITTPLKQFVEAVHADPYDPNREQNFVDKSQRLTDHSQSMTTTARLVASCGPSKSKKTVEAILD TAEKVEQLTPQLVNAGRVRLHNPGSEQHFENIHKQYADALHRLRSHVDDAIDTGEFVRASETAMRRYTNHCEGAINGADA HGLVNNSSQIARLGNRVLMTAQNEADNSEEPSFVSRVRNAADQLHNAIPPMVNNAKQIAQNPHDQYAAQNWRGTNDHLLN SVRAVGDAITGVPMSNGRHSSYQESISRASPYNPPPPSSQVIRSVNASPPTAPIIHNKMIIREDIPAPPRPPPPVELSPP PRPPPPPEYDEEEETRAFWERYPLPQASHQPMLAAAHNLHNELKQWSSQENDIVAAAKRMAILMARLSQLVRGEGGTKKD LINCSKAIADSSEEVTRLAVQLARLCTDIKMRTALLQVSERIPTIATQLKVLSTVKATMLGSASSEEDDEAMQQLVHNAQ NLMQSVKDVVRAAEAASIKIRTNSGLRLRWLRKPMWSNF
Mafft alignment of selected proteins >sp|P18206|VINC_HUMAN Vinculin OS=Homo sapiens OX=9606 GN=VCL PE=1 SV=4 ------------------------------------------------------------ ----------------------------MPV--FHTRTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQ AAQMLQSD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNSK-NQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS -KDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERR EILGTCKMLGQMTDQVADLRA-RGQGSSPVAMQKAQQVSQGLDVLTAKVENAARKLEAMT NSKQSIAKKIDAAQNWLADPNGGP-EGEEQIRGALAEARKIAELCDDPKERDDILRSLGE ISALTSKLADLRRQGKGDSPEARALAKQVA---TALQNL------QTKTNRAVANSRP-- -AKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGHRLANVMMG-PYRQDLLA KCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTT TPIKLLAVAATAPPDAPNREEVFDERAANFENHSGKLGATAEKAAAVGT-ANKSTVEGIQ ASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEQLRLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPG--------- -IPAAEVGIGV---VAEADAADAAGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >sp|P18206-2|VINC_HUMAN Isoform 1 of Vinculin OS=Homo sapiens OX=9606 GN=VCL ------------------------------------------------------------ ----------------------------MPV--FHTRTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQ AAQMLQSD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNSK-NQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS -KDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERR EILGTCKMLGQMTDQVADLRA-RGQGSSPVAMQKAQQVSQGLDVLTAKVENAARKLEAMT NSKQSIAKKIDAAQNWLADPNGGP-EGEEQIRGALAEARKIAELCDDPKERDDILRSLGE ISALTSKLADLRRQGKGDSPEARALAKQVA---TALQNL------QTKTNRAVANSRP-- -AKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGHRLANVMMG-PYRQDLLA KCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTT TPIKLLAVAATAPPDAPNREEVFDERAANFENHSGKLGATAEKAAAVGT-ANKSTVEGIQ ASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEQLRLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEAR---------------- ------------------------------------------------------------ -----KWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >sp|P18206-3|VINC_HUMAN Isoform 3 of Vinculin OS=Homo sapiens OX=9606 GN=VCL ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------MPPAFIKVENACTKLVQ AAQMLQSD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNSK-NQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS -K-----VRVLSGEISKI---------PNSP----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------WL--------GV----------------------------LIG TC---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------LILYLVIFVA--------------------------- ------------------------------------------------------------ ---------------------------------------------------------- >NP_033528.3 vinculin [Mus musculus] ------------------------------------------------------------ ----------------------------MPV--FHTRTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQ AAQMLQSD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNSK-NQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS -KDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERR EILGTCKMLGQMTDQVADLRA-RGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMT NSKQSIAKKIDAAQNWLADPNGGP-EGEEQIRGALAEARKIAELCDDPKERDDILRSLGE IAALTSKLGDLRRQGKGDSPEARALAKQVA---TALQNL------QTKTNRAVANSRP-- -AKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGHRLANVMMG-PYRQDLLA KCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKAQMQEAMTQEVSDVFSDTT TPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGT-ANKSTVEGIQ ASVKTARELTPQVISAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEQLRLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEAR---------------- ------------------------------------------------------------ -----KWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_038949159.1 vinculin isoform X1 [Rattus norvegicus] ------------------------------------------------------------ ----------------------------MPV--FHTRTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQ AAQMLQSD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNSK-NQGIEEALKNRNFTVGKMSAEINEIIRVLQLTSWDEDAWAS KKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERR EILGTCKMLGQMTDQVADLRA-RGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMT NSKQSIAKKIDAAQNWLADPNGGP-EGEEQIRGALAEARKIAELCDDPKERDDILRSLGE IAALTSKLGDLRRQGKGDSPEARALAKQVA---TALQNL------QTKTNRAVANSRP-- -AKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGHRLANVMMG-PYRQDLLA KCDRVDQLAAQLADLAARGEGESPQARALASQLQDSLKDLKTQMQEAMTQEVSDVFSDTT TPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGA-ANKSTVEGIQ ASVKTARELTPQVISAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEQLRLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPG--------- -LPAAQVGIGV---VAEADAADAVGFPFPSDMEDDSEPELLLVPANQPVNQPILAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_040558242.1 vinculin isoform X1 [Gallus gallus] ------------------------------------------------------------ ----------------------------MPV--FHTRTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTAPVSAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVR AAQMLQAD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNTK-SQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS KKDTEAMKRALALIDSKMNQAKGWLRDPNAPPGDAGEQAIRQILDEAGKAGELCAGKERR EILGTCKTLGQMTDQLADLRA-RGQGATPMAMQKAQQVSQGLDLLTAKVENAARKLEAMT NSKQAIAKKIDAAQNWLADPNGGS-EGEEHIRGIMSEARKVAELCEEPKERDDILRSLGE ISALTAKLSDLRRHGKGDSPEARALAKQIA---TSLQNL------QSKTNRAVANTRP-- -VKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGRRLANVMMG-PYRQDLLA KCDRVDQLAAQLADLAARGEGESPQARAIAAQLQDSLKDLKARMQEAMTQEVSDVFSDTT TPIKLLAVAATAPSDTPNREEVFEERAANFENHAARLGATAEKAAAVGT-ANKTTVEGIQ ATVKSARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANMQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEHLHLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEAINQPMMMAARQLHDEARKWSSKPV-T------V INEAAEAGVDI---DEEDDA--DVEFSLPSDIEDDYEPELLLMPTNQPVNQPILAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GNKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_020927737.1 vinculin isoform X1 [Sus scrofa] ------------------------------------------------------------ ----------------------------MPV--FHTRTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQ AAQMLQSD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNSK-NQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS KKDTEAMKRALASIDSKLNQAKGWLRDPTASPGDAGEQAIRQILDEAGKVGELCAGKERR EILGTCKMLGQMTDQVADLRA-RGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMT NSKQSIAKKIDAAQNWLADPNGGP-EGEEQIRGALAEARKIAELCDDPKERDDILRSLGE ISALTSKLADLRRQGKGDSPEARALAKQVA---TALQNL------QTKTNRAVANSRP-- -AKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGHRLANVMMG-PYRQDLLA KCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTT TPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGT-ANKSTVEGIQ ASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEQLRLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPG--------- -NPAAKVGIGV---VAEADAADAVGFPVPSDMEDDYEPELLLMPSSQPVNQPILAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_009457029.1 vinculin isoform X1 [Pan troglodytes] ------------------------------------------------------------ ----------------------------MPV--FHTRTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQ AAQMLQSD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNSK-NQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS KKDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERR EILGTCKMLGQMTDQVADLRA-RGQGSSPVAMQKAQQVSQGLDVLTAKVENAARKLEAMT NSKQSIAKKIDAAQNWLADPNGGP-EGEEQIRGALAEARKIAELCDDPKERDDILRSLGE ISALTSKLADLRRQGKGDSPEARALAKQVA---TALQNL------QTKTNRAVANSRP-- -AKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGHRLANVMMG-PYRQDLLA KCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTT TPIKLLAVAATAPPDAPNREEVFDERAANFENHSGKLGATAEKAAAVGT-ANKSTVEGIQ ASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEQLRLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPG--------- -IPAAEVGIGV---VAEADAADAAGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_038347906.1 vinculin isoform X14 [Canis lupus familiaris] ------------------------------------------------------------ ----------------------------MPV--FHTRTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQ AAQMLQSD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNSK-NQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS KKDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERR EILGTCKMLGQMTDQVAELRA-RGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMT NSKQSIAKKIDAAQNWLADPNGGP-EGEEQIRGALAEARKIAELCDDPKERDDILRSLGE ISALTSKLADLRRQGKGDSPEARALAKQVA---TALQNL------QTKTNRAVANSRP-- -AKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGHRLANVMMG-PYRQDLLA KCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTT TPIKLLAVAATAPPDAPSREEVFDERAANFEHHSGRLGATAEKAAAVGT-ANKSTVEGIQ ASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEQLRLAD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPG--------- -NRAAEVGIGV---VAEADAADAVGFPVPPDMEDDFEPELLLMPSNQPVNQPILAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >NP_001178299.1 vinculin [Bos taurus] ------------------------------------------------------------ ----------------------------MPV--FHTRTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQ AAQMLQSD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNSK-NQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS -KDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERR EILGTCKMLGQMTDQVADLRA-RGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMT NSKQSIAKKIDAAQNWLADPNGGP-EGEEQIRGALAEARKIAELCDDPKERDDILRSLGE ISALTSKLGDLRRQGKGDSPEARALAKQVA---TALQNL------QTKTNRAVANSRP-- -AKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGHRLANVMMG-PYRQDLLA KCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTT TPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGT-ANKSTVEGIQ ASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEQLRLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPG--------- -NPAAKVGISV---VAEAEAADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_019473128.1 vinculin [Meleagris gallopavo] ------------------------------------------------------------ ----------------------------MLM----------------------------- -----------------------LVMVGKETVQTTEDQILKRDMPPAFIKVENACTKLVR AAQMLQAD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNTK-SQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS -KDTEAMKRALALIDSKMNQAKGWLRDPNAPPGDAGEQAIRQILDEAGKAGELCAGKERR EILGTCKTLGQMTDQLADLRA-RGQGATPMAMQKAQQVSQGLDLLTAKVENAARKLEAMT NSKQAIAKKIDAAQNWLADPNGGS-EGEEHIRGIMSEARKVAELCEEPKERDDILRSLGE ISALTAKLSDLRRHGKGDSPEARALAKQIA---TSLQNL------QSKTNRAVANTRP-- -VKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGRRLANVMMG-PYRQDLLA KCDRVDQLAAQLADLAARGEGESPQARAIAAQLQDSLKDLKARMQEAMTQEVSDIFSDTT TPIKLLAVAATAPSDTPNREEVFEERAANFENHAARLGATAEKAAAVGT-ANKTTVEGIQ ATVKSARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANMQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEHLHLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEAINQPMMMAARQLHDEARKWSSKPV-T------V INEAAEAGVDI---DEEDDA--DVEFSLPSDIEDDYEPELLLMPTNQPVNQPILAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GNKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_002718451.2 PREDICTED: vinculin isoform X1 [Oryctolagus cuniculus] MGAGRGLGRRGGKGGASRRGTNRSGVPGLRGASIGRGDVRGRGAREAGYAEGSPDSVVAA PSQSLRRLPAPPFLVLCCPRFAAPLTAEMPV--FHTRTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQ AAQMLQSD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNSK-NQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS -KDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERR EILGTCKMLGQMTDQVADLRA-RGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMT NSKQSIAKKVDAAQNWLADPNGGP-EGEEQIRGALAEARKIAELCDDPKERDDILRSLGE ISALTSKLADLRRQGKGDSPEARALAKQVA---TALQNL------QTKTNRAVANSRP-- -AKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGHRLANVMMG-PYRQDLLA KCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKAQMQEAMTQEVSDVFSDTT TPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGT-ANKSTVEGIQ ASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEQLRLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPG--------- -IRAAEVGIGG---VAEADAADAVGFPVPSDMEDDYEPELLLMPSNQPVNQPILAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_024109838.1 vinculin isoform X2 [Pongo abelii] ------------------------------------------------------------ ----------------------------MPV--FHTRTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQ AAQMLQSD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNSK-NQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS -KDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERR EILGTCKMLGQMTDQVADLRA-RGQGSSPVAMQKAQQVSQGLDVLTAKVENAARKLEAMT TSKQSIAKKIDAAQNWLADPNGGP-EGEEQIRGALAEARKIAELCDDPKERDDILRSLGE ISALTSKLADLRRQGKGDSPEARALAKQVA---TALQNL------QTKTNRAVANSRP-- -AKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGHRLANVMMG-PYRQDLLA KCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTT TPIKLLAVAATAPPDAPNREEVFDERAANFENHSGKLGATAEKAAAVGT-ANKSTVEGIQ ASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEQLRLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPG--------- -IPAAEVGIGV---AAEADAADAAGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_003813044.1 vinculin isoform X2 [Pan paniscus] ------------------------------------------------------------ ----------------------------MPV--FHTRTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQ AAQMLQSD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNSK-NQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS -KDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERR EILGTCKMLGQMTDQVADLRA-RGQGSSPVAMQKAQQVSQGLDVLTAKVENAARKLEAMT NSKQSIAKKIDAAQNWLADPNGGP-EGEEQIRGALAEARKIAELCDDPKERDDILRSLGE ISALTSKLADLRRQGKGDSPEARALAKQVA---TALQNL------QTKTNRAVANSRP-- -AKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGHRLANVMMG-PYRQDLLA KCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTT TPIKLLAVAATAPPDAPNREEVFDERAANFENHSGKLGATAEKAAAVGT-ANKSTVEGIQ ASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEQLRLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPG--------- -IPAAEVGIGV---VAEADAADAAGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_019668863.1 vinculin isoform X1 [Felis catus] ------------------------------------------------------------ ----------------------------MPV--FHTRTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQ AAQMLQSD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNSK-NQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS KKDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERR EILGTCKMLGQMTDQVAELRA-RGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMT NSKQSIAKKIDAAQNWLADPNGGP-EGEEQIRGALAEARKIAELCDDPKERDDILRSLGE ISALTSKLADLRRQGKGDSPEARALAKQVA---TALQNL------QTKTNRAVANSRP-- -AKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGHRLANVMMG-PYRQDLLA KCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTT TPIKLLAVAATAPPDAPSREEVFDERAANFEHHSGRLGATAEKAAAVGT-ANKSTVEGIQ ASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEQLRLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKRG--------- -NPAAEVGIGV---VAEADAADAVGFPVPPDMEDDYEPELLLMPSSQPVNQPILAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_027818089.1 vinculin isoform X1 [Ovis aries] ------------------------------------------------------------ ----------------------------MPV--FHTRTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQ AAQMLQSD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNSK-NQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS -KDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERR EILGTCKMLGQMTDQVADLRA-RGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMT NSKQSIAKKIDAAQNWLADPNGGP-EGEEQIRGALAEARKIAELCDDPKERDDILRSLGE ISALTSKLGDLRRQGKGDSPEARALAKQVA---TALQNL------QTKTNRAVANSRP-- -AKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGHRLANVMMG-PYRQDLLA QCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTT TPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGT-ANKSTVEGIQ ASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEQLRLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPG--------- -NPAAKVGISV---VAEAEAADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_004049661.1 vinculin isoform X2 [Gorilla gorilla gorilla] ------------------------------------------------------------ ----------------------------MPV--FHTRTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQ AAQMLQSD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNSK-NQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS -KDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERR EILGTCKMLGQMTDQVADLRA-RGQGSSPVAMQKAQQVSQGLDVLTAKVENAARKLEAMT NSKQSIAKKIDAAQNWLADPNGGP-EGEEQIRGALAEARKIAELCDDPKERDDILRSLGE ISALTSKLADLRRQGKGDSPEARALAKQVA---TALQNL------QTKTNRAVANSRP-- -AKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGHRLANVMMG-PYRQDLLA KCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTT TPIKLLAVAATAPPDAPNREEVFDERAANFENHSGKLGATAEKAAAVGT-ANKSTVEGIQ ASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEQLRLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPG--------- -IPAAEVGIGV---VAEADAADAAGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_043332427.1 vinculin isoform X2 [Cervus canadensis] ------------------------------------------------------------ ----------------------------MPV--FHTRTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQ AAQMLQSD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNSK-NQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS -KDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERR EILGTCKMLGQMTDQVADLRA-RGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMT NSKQSIAKKIDAAQNWLADPNGGP-EGEEQIRGALAEARKIAELCDDPKERDDILRSLGE ISALTSKLADLRRQGKGDSPEARALAKQVA---TALQNL------QTKTNRAVANSRP-- -AKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGHRLANVMMG-PYRQDLLA KCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTT TPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGT-ANKSTVEGIQ ASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEQLRLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPG--------- -NPAAKVGISV---VAEAEAADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_043332426.1 vinculin isoform X1 [Cervus canadensis] ------------------------------------------------------------ ----------------------------MPV--FHTRTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQ AAQMLQSD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNSK-NQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS KKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERR EILGTCKMLGQMTDQVADLRA-RGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMT NSKQSIAKKIDAAQNWLADPNGGP-EGEEQIRGALAEARKIAELCDDPKERDDILRSLGE ISALTSKLADLRRQGKGDSPEARALAKQVA---TALQNL------QTKTNRAVANSRP-- -AKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGHRLANVMMG-PYRQDLLA KCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTT TPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGT-ANKSTVEGIQ ASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEQLRLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPG--------- -NPAAKVGISV---VAEAEAADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >KAF4018928.1 hypothetical protein G4228_011024 [Cervus hanglu yarkandensis] ------------------------------------------------------------ ----------------------------MPV--FHTRTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQ AAQMLQSD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNSK-NQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS -KDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERR EILGTCKMLGQMTDQVADLRASRGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMT NSKQSIAKKIDAAQNWLADPNGGP-EGEEQIRGALAEARKIAELCDDPKERDDILRSLGE ISALTSKLADLRRQGKGDSPEARALAKQVA---TALQNL------QTKTNRAVANSRP-- -AKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGHRLANVMMG-PYRQDLLA KCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTT TPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGT-ANKSTVEGIQ ASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEQLRLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPG--------- -NPAAKVGISV---VAEAEAADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_018094934.1 vinculin isoform X1 [Xenopus laevis] ------------------------------------------------------------ ----------------------------MPV--FHTKTIESILEPVAQQISHLVIMHEEG EVDGKAIPELTAPVAAVQAAVSNLVRVGKETVQTTEDQIMKRDMPPAFIKVENACAKLVQ AAQMLNAD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVESMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKDL LPVLISAMKIFVTTKSSR-SQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS -KDTEAMKRALALIDSKINQAKGWLRDPNAPPGDAGEQAVRQILDEAGKVGELCAGTERK DILGTCRTLGQMTDQVSDLRS-RGQGATPIAMQKAQQVSQGLDVLTSKVKNAAHKLEALT NSKQAIGKKIDAAQSWLADPNGGP-EGEENIRTILAEAKKIADLCEDPKDKEDILRSLGE IAALTAKLTDLRRQGKGDSPEARALAKQIA---TSLQNL------QTKVNRAVANSRP-- -VKAAVNMDGKVEQAQRWIDNPSVDDRGVG-QAAIRSLVAEGRRLANSMTG-PFRQDMIA KCDRVEQLAGQLAELALRGEGDTPLAQAVAAQLQEALKDLKGKMQEAMTQEVSDVFSDTT TPIKLLAVAATSPPDAPNRDEVFEERAANFENHSARLGATAEKAAAVGS-ANKATVEGIQ AAVKSARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTRSL LDASEEAIKKDIDKCKVAMANMQPQMLVAGATSIARRANRILLVAKREMENSEDPKFRDT VKNASDELSKTISPMVMEAKAVAGNISNPALQKGFLDSGYRILGAVAKVREAFQP-PEP- --------------EFPPPPPDLDQLRLSD------------------DAAPPKPPLPE- -GEVPPPRPPPPDEKDEEFPEQKVGEVVNQPMMVAARQLHDEARKWSSKSPGNYDYPAPQ GREAVISEVEQAQEEEEEEA--SVEFALSSDIEDDYEPELLLVPEGQPVNQPMLAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GNKRALIQCAKDIAKASDE VTKLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWARKTPWYQ- >XP_005156897.1 vinculin isoform X1 [Danio rerio] ------------------------------------------------------------ ----------------------------MPV--FHTKTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTSPVAAVQAAVSNLVRVGKETVQTTEDKIMKRDMPSAFIKVENACAKLVE AAQMLRTD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLITYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVTSMNTVKEL LPVLISAIKIFVTTKCTK-SHGVEEALKNRNYTFDKMTAEINEIIRVLQLTSWDEDAWAN -KDTEAMKRALALIESKMGQAKGWLRDPNALPGDPGEHALRQILDEAGKVGELCAGKERR EILGTAKTLGQMTDQVSDVRA-RGQGATPMGMQKAQQVAQGLDILVGKVENAARKLEALT NAKQAIAKRIDNAQSWLADPNGGP-EGEENIRALLAEAKRIADLCEDPKERDDILRSIGE IAGLTARLVELRRIGKGDTPEARALAKQIG---TALQNL------QAKTNRAVANMRP-- -AKAAVTLEGKMEQALRWINNPGVDDHGVG-QAAIRGLIAEGRRLASSLPG-PYRQELLA KCEQVEQLMMQLADLAARGEGESPQARAVAAHLLEAIKDLKAKMQEAMTQEVSDVFSDTT TPIKLLAVAATAPLEAPNREEVFEERASNFENHASRLGATAEKAAAVGT-ANKSTVEGIQ AAVKSARDLTPQVTSAARILLKNPGNQAAYEHFDTMKNQWIDNIEKMTSLVDEAIDTKSL LDASEEAIKKDIDKCRVAMANVQPQMLVAGATSIARRANRVLLVAKREVENSEDPKFREL VKAASDELGRTISPMVMAAKGVAGNIQDPGLQKGFLDSGYRILAAVGKVREAFQP-QEL- --------------DFPPPPPDLDQLHVND------------------DQAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEMVSEPMMVAARSLHDEARKWSSKPEVP-----DE GFEAAEAEVDI---DDEDEF---------TDNEDDYEPELLLMSSNQPVNQPILAAAQSL HQEARKWSSKGNDIIGAAKRMALLMAEMSRLVR----GGS-GNKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SEEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_020565294.1 vinculin isoform X4 [Oryzias latipes] ------------------------------------------------------------ ----------------------------MPV--FHTKTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTVPVAAVQAAVSNLVRVGKETVQTTEDQVMKRDMPPAFIKVENSCSKLVQ AAQMLKSD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLITYTKNLGPGMTKMSKMIEERQQELTHQEHRQMLVSSMNTIKEL LPVLISAIKIFVATKSTR-GAGVEEAERNRRFTFEKMSTEINEIIRVLQLTTWDEDAWAN -KDMEALKRSLALIESRMAQAKSWLKDPHGQPGDSGELALRVILDEAGKVGELCAGKERK DVLATTKALGQMTDQIADLRA-RGQGPTPGCVQRAGQCSQGLDLLYGKVDSAARRLEALI SAKQAIARKLDAAQAWLADPNGGP-EGEENIRALLAEAKRIADLCEDPKERDDILRSISE IVGLTTRLAELRKQGKGDSPEARALAKQIG---GALLTL------QSKTNRAVANMRP-- -AKPAVTLEGKMEQALRWVNNPGVDDRGVG-QAAIRGMVGEGRRLAAGLLG-PYRQDMIG RCDRTEGLMAALADMAGRGEAEAPHARVTAAQLQDSLKDLRQHMQEVMTQDVSDVFSDTT TPIKLLAVAATAPPDAPNREEVFDERAGNFETHASRLGATAEKAAAVGT-ANKSTVEGIH ATVKHARELTPQVTSAARILLRNPGNKAAYEHFDTMKNQWIDNVERLTGLVDEAIDTKSL LDASEEAIKKDIDKCRVAMANVQPQMLVAGATSIARRANRVLLVAKREVENSEDPRFRDC VKHASDILSHTISPMVMDAKAVAGNIQDKALQKAYLDSCLRILAAVGKVREAFQP-QEP- --------------DFPPPPPDLDQLHVSD------------------EQAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEVLSEPMMVAARQLHDEARKWSSKPE--------- -DEEAIEEREV---DDEDEF---------TDGEDDYEPELLMMPSNQPVNQPILAAAQSL HQEARKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GNKRALIQCAKDIAKASDE VTRLAKEVAKQCTDRRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SEEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_030297248.1 vinculin-like isoform X4 [Sparus aurata] ------------------------------------------------------------ ----------------------------MPV--FHTKTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTVPVAAVQAAVSNLVRVGKETVQTTEDQVMKRDMPPAFIKVENSSSKLVQ ASQMLKAD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLITYTKNLGPGMTKMSKMIEERQQELTHQEHRQMLVNSMNTVKEL LPVLISAIKIFVTTKSSR-GAGVEEAERNRRFIFEKMSAEINEIIRVLQLTTWDEDAWAN -KDMEALKRSLALIESKMAQAKGWLKDPHGQPGDPGEVALRVILDEAGKVGELCAGRERK DILATAKALGQMTDQIADLRA-RGQGPSPGCVQRAGQCSQGLDLLFGKVDCAARRLEALI NAKQAIARRLDAAQAWLADPNGGP-EGEENIRALLAEAKRIADLCEDPKERDDILRSISE IAGLTARLVELRKQGKGDSPEARALAKQIG---AALLTL------QSKTNRAVANMRP-- -AKPAVTLEGKMEQALRWANNPGVDDRGVG-QAAIRGMVGEGKRLAGGLLG-PYRQDMIG RCDRTEALMTSLADMANRGEAEAPHARATAAQLQDSLKDLRQHMQEVMTQEVSDVFSDTT TPIKLLAVAATAPPDAPNRAEVFEERAGNFEAHAGRLGATAEKAAAVGT-ANKSTVEGIH AAVKHARELTPQVTSAARILLKNPGNKAAYEHFDTMKNQWIDNVEKLTGLVDEAIDTKSL LDASEEAIKKDIDKCRVAMANVQPQMLVAGATSIARRANRVLLVAKREVENSEDPRFRDT VKHASDILSHTISPMVMDAKAVAGNIQDKALQKAYLDSCLRILAAVGKVREAFQP-QEP- --------------DFPPPPPDLDQLHVSD------------------EQAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKVGEVLSEPMMVAARQLHDEARKWSSKPE--------- -DEEAVEEREV---DDEDEF---------TDGEDDYEPELLMMPSNQPVNQPILAAAQAL HQEARKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GNKRALIQCAKDIAKASDE VTRLAKEVAKQCTDRRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SEEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >OWK07868.1 VCL [Cervus elaphus hippelaphus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MLQSD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNSK-NQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS -KDTEAMKRALASIDSKLNQAKGWLRDPNASP-----------------------GKERR EILGTCKMLGQMTDQVADLRA-RGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMT NSKQSIAKKIDAAQNWLADPNGGP-EGEEQIRGALAEARKIAELCDDPKERDDILR---- ---------------KGDSPEARALAKQVA---TALQNL------QTKTNRAVANSRP-- -AKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGHRLANVMMG-PYRQDLLA KCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTT TPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGT-ANKSTVEGIQ ASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEQLRLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPG--------- -NPAAKVGISV---VAEAEAADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLL-----------QLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_015799676.1 PREDICTED: vinculin-like isoform X4 [Nothobranchius furzeri] M----------------------------------------------------------- ----------------------------MPV--FHTKTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLSVPVAAVQAAVSNLVRVGKETVQTTEDQLMKRDMPPAFIKVENSSSKLVQ AAQMLKAD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLITYTKNLGPGMTKMSKMIEERQQELTHQEHRQMLINSMNTVKEL LPVLISAIKIFVATKSSR-GAGVEEAERNRKFTFEKISAEMHEIIRVLQLTTWDEDTWAN -KDMEALKRSLALIESKMAQAKSWLKDPHGQPGDPGEVALRVILDEAGKVGELCAGKERK DILATTKALGQMSDQIADLRV-RGQGPTPGCVQRAGQCSQGLDLLFGKVDSAARRLEALI NAKQAIARRLDAAQAWLADPNGGA-EGEENIRALLAEAKRIADLCEDPKERDDILRSINE IAGLAARLVELRKQGKGDSPEARALAKQIG---AALLNL------QSKTNRAVANMRP-- -AKPAVTLEGKMEQALRWVNNPGVDDRGVG-QAAIRGMVGEGKRLAGGLLG-PYRQDMIG RCDRTEALMTSLADMANRGEAEAPHARATAAQLQDTLKDLRQHMQEVMTQEVSDVFSDTT TPIKLLAVAATAPPDAPNREEVFEERAGNFETHAGRLGATAEKAAAVGT-ANKSTVEGIH AAVKHARELTPQVTSAARILLKNPGNKAAYEHFDTMKNQWIDNVERMTGLVDEAIDTKSL LDASEEAIKKDIDKCRVAMANVQPQMLVAGATSIARRANRVLLVAKKEVENSEDPRFRDT VKHASDILSHTISPMVMDAKAVAGNIQDKALQKAYLDSCLRILAAVGKVREAFQP-QEP- --------------DFPPPPPDLDQLHVND------------------EQAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKASEVLSEPMMVAARQLHDEASKWSSKPE--------- -DEEAVEEREV---DDEDEF---------TDGEDDYEPELLMMPSNQPVNQPILAAAQSL HQEARKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GNKRALIQCAKDIAKASDE VTRLAKEVAKQCTDRRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SEEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_021139948.1 vinculin [Columba livia] ------------------------------------------------------------ ----------------------------MPV--FHTRTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLIYSEILNLKYDFFLPQVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQ AAQMLQAD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNSK-SQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS -KDTEAMKRALALIDSKMNQAKGWLRDPNAPPGDAGEQAIRQILDEAGKAGELCAGKERR EILGTCKTLGQITDQLSDLRA-RGQGATPMAMQKAQQVSQGLDLLTAKVENAARKLEAMT NSKQAIAKKIDAAQNWLADPNGGS-EGEEHIRGILAEARKVAELCEEPKERDDILRSLGE ISALTAKLSDLRRHGKGDSPEARTLAKQIA---TALQNL------QSKTNRAVANTRP-- -VKAAVHLEGKIEQAQRWIDNPTVADRGVG-QAAIRGLVAEGRRLANVMMG-PYRQDLLA KCDRVDQLAAQLADLAARGEGESPQARAIAAQLQDSLKDLKTRMQEAMTQEVSDIFSDTT TPIKLLAVAATAPSDAPNREEVFEERAANFENHAARLGATAEKAAAVGT-ANKTTVEGIQ ATVKSARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANMQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKVASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEQLHLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEAINQPMMMAARQLHDEARKWSSKPDVT------V INEAAES-VDI---DDEDDA--DVEFTLPSDTEDDYEPELLLMPTNQPVNQPILAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GNKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_005699280.1 PREDICTED: vinculin isoform X1 [Capra hircus] ------------------------------------------------------------ ----------------------------MPV--FHTRTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQ AAQMLQSD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNSK-NQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS -KDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERR EILGTCKMLGQMTDQVADLRA-RGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMT NSKQSIAKKIDAAQNWLADPNGGP-EGEEQIRGALAEARKIAELCDDPKERDDILRSLGE ISALTSKLGDLRRQGKGDSPEARALAKQVA---TALQNL------QTKTNRAVANSRP-- -AKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGHRLANVMMG-PYRQDLLA QCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTT TPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGT-ANKSTVEGIQ ASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEQLRLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPG--------- -NPAAKVGISV---VAEAEAADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_025068505.1 vinculin isoform X1 [Alligator sinensis] ------------------------------------------------------------ ----------------------------MPV--FHTRTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQ AAQMLQAD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNCK-SQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS KKDTEAMKRALALIDSKMNQAKGWLRDPNAPAGDAGEQAIRQILDEAGKVGELCAGKERR EILGTCKMLGQMTDQVADLRA-RGQGATPVAMQKAQQVSQGLDLLTAKVENAARKLEAMT NSKQAIAKKIDAAQNWLVDPNGGS-EGEEHIRGIMAEARKIAELCEEPKERDDILRSLGE ISALTAKLSDLRRHGKGDSPEARALAKQIA---TSLQNL------QSKTNKVVANTRP-- -VKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGRRLANVMME-PYRQDLLA RCDRVEQLAAQLADLAARGEGESPQARAIAAQLQDSLKDLKTRMQEAMTQEVSDVFSDTT TPIKLLAVAATAPPDAPNRDEVFGERAANFENHAARLGATAEKAAAVGT-ANKTTVEGIQ ATVKSARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDDLSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEQLHLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPDVT------E VNEATEAGVDI---DEEDDA-DDAEFTLPSDIEDDYEPELLLIPSNQPVNQPILAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_006273854.1 PREDICTED: vinculin isoform X2 [Alligator mississippiensis] ------------------------------------------------------------ ----------------------------MPV--FHTRTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQ AAQMLQAD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNCK-SQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS -KDTEAMKRALALIDSKMNQAKGWLRDPNAPAGDAGEQAIRQILDEAGKVGELCAGKERR EILGTCKMLGQMTDQVADLRA-RGQGPTPMAMQKAQQVSQGLDLLTAKVENAARKLEAMT NSKQAIAKKIDAAQNWLADPNGGS-EGEEHIRGIMAEARKIAELCEEPKERDDILRSLGE ISALTAKLSDLRRHGKGDSPEARALAKQIA---TSLQNL------QSKTNKVVANTRP-- -VKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGRRLANVMME-PYRQDLLA KCDRVEQLAVQLADLAARGEGESPQARAIAAQLQDSLKDLKTRMQEAMTQEVSDVFSDTT TPIKLLAVAATAPPDAPNRDEVFGERAANFENHAARLGATAEKAAAVGT-ANKTTVEGIQ ATVKSARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDDLSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEQLHLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPDVT------E VNEATEVGVDI---DEEDDA-DDAEFTLPSDIEDDYEPELLLIPSNQPVNQPILAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_020770146.1 vinculin isoform X1 [Odocoileus virginianus texanus] ------------------------------------------------------------ ----------------------------MPV--FHTRTIESILEPVAQQISHLVIMHEEG EVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQ AAQMLQSD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKEL LPVLISAMKIFVTTKNSK-NQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWAS KKDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERR EILGTCKMLGQMTDQVADLRA-RGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMT NSKQSIAKKIDAAQNWLADPNGGP-EGEEQIRGALAEARKIAELCDDPKERDDILRSLGE ISALTSKLADLRRQGKGDSPEARALAKQVA---TALQNL------QTKTNRAVANSRP-- -AKAAVHLEGKIEQAQRWIDNPTVDDRGVG-QAAIRGLVAEGHRLANVMMG-PYRQDLLA KCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTT TPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGT-ANKSTVEGIQ ASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSL LDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREA VKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQP-QEP- --------------DFPPPPPDLEQLRLTD------------------ELAPPKPPLPE- -GEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPG--------- -NPAAKVGISV---VAEAEAADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GTKRALIQCAKDIAKASDE VTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGFTLRWVRKTPWYQ- >XP_040176600.1 vinculin isoform X1 [Rana temporaria] ------------------------------------------------------------ ----------------------------MPV--FHTKTIESILEPVAQQISHLVIMHEEG EVDGKAIPELTTPVAAVQSAVSNLVRVGKETVQTTDDQMMKRDMPPAFIKVENACAKLVQ AAQMLHAD---------PYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGI LEYLAVAEVVESMEDLVTYTKNLGPGMTKMAKMIDDRQQELTHQEHRVMLVNSMNTVKDL LPVLISAMKIFVTTKSSR-SQGVEEALKNRNFTVDKMSAEINEIIRVLQLTSWDEDAWAS KKDTEAMKRALAHIGSKMNQAKGWLRDPNAPPGDAGEQAVRQILDEAGKVGELCAGKERR DILGTCKALGQITDQVADLRA-RGQGATPTAMQKAQQVSQGLDLLTAKVENAARKLEALT NSKQAIGKKIDTAQSWLADPNGGP-EGEETIREILAEAKRIAELCEDPKDREDILRSLGE IAACTAKLSDLRRQGKGDTPEARALAKQIG---TSLQNL------QTKVNRAVANSRP-- -VKAAVNMEGKVEQAQRWIDNPSVDDRGVG-QAAIRGMVAEGRRLANSMIG-PYRQDMMA RCDCVEQLAGQLAELAARGEGDTPHARAVAAQLQDALKDLKAKMQEAMTQEVSDVFSDTT TPIKLLAVAATSPPDAPNREEMFDDRAANFESHAARLGATAEKAAAAGS-ANKATVEGIQ ATVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTRAL LDASEEAIKKDIDKCKVAMANMQPQMLVAGATSIARRANRIMLVAKREVENSEDPKFREA VKNASDDLSKTISPMVLEAKAVAGNISDPALQKGFLDSGFRILGAVAKVREAFQP-PEP- --------------DFPPPPPDLEHLRLTD------------------EAAPPKPPLPE- -GEIPPPRPPPPDEKDEEFPEEKVGEV-NEPMMVAARQLHEEARKWSSKSPGSPAPATPQ GTEAVVSEVEQ-EREEEEEA--SVEFVL-SDVEDDYEPELLLVPEGQPVNQPMLAAAQSL HREATKWSSKGNDIIAAAKRMALLMAEMSRLVR----GGS-GNKRALIQCAKDIAKASDE VTKLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNI--------- -SDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTD-AGITLRWARKTPWYQ- >XP_039272784.1 vinculin-like isoform X1 [Styela clava] ------------------------------------------------------------ ----------------------------MPV--FHTKTIQMILEPVAEQVSTLVLIHEQG K-DGNQMPDLINPILTVKAAVSNLVKVGKDQIKDTKDEILKLDTPPALEKVETSADMLVQ ASQLLSIDQKRETAEMTPEGMEGRKKLIAGSRGILQGTSDLLLVFDEAEVRRICKVCRNV RDYLNQSSIVAGMEDLVVFVKSLTPGTTTLARMIGDRCKDLTNQNHVAALTEEMDQVKAY IPGLISSLKAFVQTVDKP-GKAQEAAIGNREYYTTQISERITEIIRLLQLVSTDDANTDP -LNVLQLKQTQQKMARKMQPAKNWLNNPNAPAGGPGELALREILDGAKEIGNQAGGPLGD KILGTTAHLGTLTDQLSDLRA-NGKGNSAEAKQIATQINGELDQLMEDVDDAIEAMDKLA MAHSGMVKTMPAAREWLANLSAKPKEGAEHVHNVTKAGREIAMGLGSCKDRDDIIQLCDE IDDMMQKLEEFRTLGLGDTPEAVALSKSIA---DKLTAL------NAKVAKALAS----- -KKSVATLDSKMEEIARWLDNPGVKDGGRGLARSTKSLLGDARQIAARISDPNARFALLK NVAECDRLLKDLEHLIQTGRGDSKEAKEIAKKLQKKLEEVKKQMKDALVRAVADEFADTT TSLKQLHSAAIAPLDTLNREENFEGKALTFQSQSTRLADLARQAVGASDLVSQEKVDEVK KKAVRIEGLTPQVINAGRIVLSNPENKTSLEHFETLKQDWTRNMDELTDMVDDSVDFATF MDASEESMRREHEACVKAVKLDKPADALPLAGNISRRAHRILMTGKREMQNTDDPQYVEQ LRKNLNAIQQQLDPTLKSARTYAGAPANRKNQNDFIDNEDKLIQAVSNLQKTVKA----- ------------------EIIEKEKQRKAL------------------EEPPPVPPMPVC QTELPPPVPPPPEEE--------------------------------------------- ------------------------------------------FPEVE-SNQPIMVAAKEL HEEAKKWESTGNNIIAAAKKMALLMAKMSRLVD----GEE-GSRSELIQCAKDIAKASND VTKYAKEVATQCTDKRIKTDMMKTLDRLPTISTQLRILSTVKATTLGNPSQ----E---- -KEEDAEQATEMLVHNAQNLMQSVKETVRYAEAASIRIRTD-AGLTMRWVRKDN---- >CAE1284850.1 VCL [Sepia pharaonis] ------------------------------------------------------------ ----------------------------MPV--FHTKTIEGILEPVAQQVSKLVILHEEA E-DGNAMPDLARPVQAVKLAVDNLVKVGYDTINSSEDQILKQDMPPALHRVEDASVLLLE ASDMLRDD---------PFSAPARKKLIEGSRGILQGTSSLLLAFDESEVRKIIRVCKNV LEYLAITEVVDKMEDLVTYVKNLSPVLTKIIKEVDAREKELTHQVHRDMLIRSLDQVKNL TPVLISGVKIFITAKET--STGFAEAQNNRDFVVRKMSDEIHEIIRVLQLTTYDEEEWDA -DDLTVMKKAQCAIEGKLQQAADWLQDPAALVGSAGDKALHQILE--------------- ------------------------------------------------------------ ------------------------------------DARKIAERCSNPNERDSILRTVGD IESMANTLAELRQQGKGSSPQAMSLAREIQ---NKLRDL------TQLTQNGIVNTERSG VRKPAPTVSGKVEQAQRWLVNPGLDDKGLG-EQATRMVVAEGRKVAESLTG-PQRAELLR LCDETEILTNQLSDLIRRGQGNSPQAQACARHLSEKLHALKNKIGEGLVNQVAEDFIDMT TPLKQLSDAAMAPLGVPGREQNFDEKARNFLTQSSKLSDTANMVATAGGCCNKKTVEAIF ATSAQANDLSPQVVNAAKIVLINPENQAAVDHFDLLKKQWTENMERLRTLVDEATDTEAF IRATEVGIKKDTEKVEDGIRAVSPQMVVANASNIARRANRVLQVAQQEAENSEDPAFVEK VNQSSDILKSSITPMVQQAKAVSMNPKDPAAANNWRKENNNLIAAVGQVRESVTVSPKTS ----------DLYGQPFPQPPDMSQLHISD--------------------APPRPPLPH- --ETVPPRPPPPETDDED------------------------------------------ --------------------------------------ESA-FPMPQ-ANQPIMMAAHDL HMETKQWSSKDNEIIVAAKKMALLLAKLSHLVS----CES-TCKWIW------------- -----------CTAHKM------------------------------------------- ---------------------------------------------------------- >XP_030848750.1 vinculin isoform X6 [Strongylocentrotus purpuratus] ------------------------------------------------------------ ----------------------------MPV--FHTKTIEAILDPVAQQVSQLVILHEEA Q-DGNAMPDLSRPVMAVSAAVQNLVKVGRDTANSTDDKILKQEMPPAFQGVEQSATKLYE AAMMLKED---------PYSSPARKMLIDGARGILSGTSDLLLCFDQSEVRKIVRVAKGV LEYLAVSEVVESMEDLVTFVKNLSPGMANLANKVTGRSKELTHTAHANGLVNHTENLKRT TPILVSSIKIFVTTLQKG-GAGRDEAQQNRNFIIGRMSHDVNEIIRILQLTSADDDDWSM -DDLTIMKKSLLNITNQMNMAQTWLANSNAEPGGLGEKAVRDILR--------------- ------------------------------------------------------------ ------------------------------------DARRVADRLEGP-QREHLLATINE IEVMMNELCALRAKGQGNSPRALQLAKQIA---EKLGYL------HQEVDFAVKDAVKSG VTRTAYTLAGKVEQAQKWLRNPAQDDKGVG-RRAVAGIVAQGRKVAQNLSE-PERGELLR LCDEVESLSQQITDLVNRGQGNSPQCLDAARRLAERLPSLQKMIENALAKEVAEVFMDTT TPLKELERAAKAPADDPNRQQTYTSKATIFLTHANKISDTAKLVAEAGASNDRPLVEELN NKAQEVKDLAPQVVAAGKVLLLNPGEQTAVSHFDELKREYMGKVETLTDLVDQAVDTVEF VKASEEAIKRDSEKVAQAIQQNDPNVIAAKASSIARRAQRVAVVASKEAANSEDPKFVQD VSRAANQLSGDIPPSVTAAKGVTLNPADRNAQDKWFTANKQVQSDVGDVRQALTV-NQE- --------------PIMPPPPDMSRLQLE-------------------EAAPPRPPLP-- -GDVPPPRPPPPEDTSLP------------------------------------------ ------------------------------------------LPEQG-SHQPIMQAAYDL HVETEQWSSKDNDLIAAAKRMAQLMAAMSKHVS----GEK-TSKKELIEIAKKIAQASLE VVRLAGEIAAQCTDKRMKNNLLQVCERIPTISTQLKILSTVKAVMLGSQE---------- --SEEDMEATEMLVGNAQNLMKAVKETVRAAKAASIKIRTD-AGYKMRWVRQRPWYQ- >XP_031557163.1 vinculin-like [Actinia tenebrosa] ------------------------------------------------------------ ----------------------------MPV--FHTKTIESILDPVAQQVSQLVIFHEEG E-DGRAMPDLSAPIKAVGAAVANLVKVGQQTAANSKDKILRQEMPLAFTRVEESSTFLVE AAKILKND---------PYSSVARKKLIDGARGILSGTSALLLTLDEAEVRRILHVCKSL LEYFPVAEMVEEMTDLVTFVTNLTPGTTSLAKQVEERAEELTHHEHRDILKSCIGKIKHL VPLLISAMKAFVKT--PL-GAGRAEAQENRNFIITKICAEITEIMRVLQLTSTEENKGD- -DPLYDMKKAVSVFDSKFDKAREWIGEPTCDAGGLGDQAVRECIQ--------------- ------------------------------------------------------------ ------------------------------------QGRLMGSVCQDP-QKNKIQRCCDD LDRLMSELETLRSQGKGTTPRGLELSREVD---KQLGVL------RNLMDEAIHHQGISG IKKPANTFVGKMEQAQQWLANPSGDHTGLG-EKAIRECINDARKIADKSSG-PERMELLK LCNEVERLTDELADLKRRGLGNSPQAYALANKLSNKLDELHRQTQRAIANQVAQNFVDPT GQIKQLERAAKAPRGTPNREADFETKAGNFEHQANEMADTAFRFANNSSTTRKKSLEDIR KTAQYMKELTPQVSHAAKVLLDNPDEPAAGEHFEKLKDEWVQETTKLANSIDSTADTLQL IEACEEAINRDVLACDNALSQENPQLVVAKTSNIARMAQRIAKLVNAEAENTEDPEFRAK LEQMSRNIQDVIAPLAIEAKSVVSNIKDKQGHERLRAAMRRVQRNVGEVRKVFIDRATQS -------DDEDFPPPPPPPPPEMEDLSLHER-----------------ERAPPRPPLPRE MTTSAPPRPPPPAMEPKI------------------------------------------ ----------------------------------DMNLQSM-LESPP-EDNRMAMAASNL HKEILKWEEQGNDMIQAAKRMAVLFAKMSKFMRDEEEGEP-HSKKELIQLAKEIATASKE IVKFGNRACQKCSDKRLKASMQQTIDRIPTISTQLKIVSTVKATMIGSQE---------- --LEEDREATETLVGCAENLMSAVRQTVRETEAASVKMRTD-AGLVMHWKKKQY---- >XP_026301464.1 vinculin isoform X3 [Apis mellifera] ------------------------------------------------------------ ----------------------------MPV--FHTKTIESILEPVAQQVSRLVILHEEA E-DGNAMPDLGKPVQAVSMAVANLVKVGKETINSSDDALLKQDMPAALQRVEGASRLLEE ASAMLKQD---------PYSGPARKKLIEGSRGILQGTSSLLLCFDESEVRKIIRECKRV LDYLAVTEVIETMEDLVHFLKNLSPCLSKVSKEVSAREKELTHQVHREILVRCLEQVKTL APILICSMKIFIHIISQG-GKGAEEAAENRNYLSGRMSDELNEIIRVLQLTTYDEEEWDA -DQLTVLKKAQSAIESRIRAAYDWLDDGFALRGGLGEKSLRQIVE--------------- ------------------------------------------------------------ ------------------------------------QAQRLAERYLPPSQAESLQKLTSQ IVTMTNALCELRQNEKGSTPQAEALARSIK---EKTNEL------RSSIASAIIAADKSG TTQTAHTVAGRLEQANKWLLNPQHDDKGLG-QRAIALIIHEGKKVAEGLPG-IHKAEILQ LCDEVDNLSHQLGDLCAHGQGNTPRAQEIARQLSHKLYELKNRIQQAVVSRVVEDFIDIT TPLKQFTDAVLTPEGSLGRDQNFNDKTHALQTFSNRATKTAKMVAAGGSGGNKKLAEALT TSASQVESLTPQLINAGRIRMTYPDSKAADEHFENLRQQYADTIQRVRALCDEATDSGDF IRTSEEQMQKHSFLCEEAIAKSHPQKMVDNTAAIARLANRVILVAKQESDNSEDTAFIQR VNQATDILQNSVAPMVQDAKLVAININDNNAVSHWRESNRTLLSNVGQVRKAIVLQPDVI ------------------SPPEVSQLHLND------------------EVVPPRPPLPG- -GDIPPPRPPPPETDDED------------------------------------------ --------------------------------------E-MFMHAPQ-PNQPIMMAAHGL HQEVRQWSSKDNEIIAAAKKMAILMGRLSGLVR----GEG-GNKRDLIACAKAIAEASQE VTRLAKELARECTDKRIRTNLLQVCERIPTIGTQLKILSTVKATMLGAQETLPTWEELML YGTEEDQEATDMLVGNAQNLMQSVKETVRAAECASIKIRTA-SGMKLRWVRRQPWYQY >NP_001284813.1 vinculin, isoform B [Drosophila melanogaster] ------------------------------------------------------------ ----------------------------MPV--FHTKTIESILDPVAQQVSRLVILHEEA E-DGNAMPDLSRPVQVVSAAVANLVKVGRDTINSSDDKILRQDMPSALHRVEGASQLLEE ASDMLRSD---------PYSGPARKKLIEGSRGILQGTSSLLLCFDESEVRKIIQECKRV LDYLAVAEVINTMEQLVQFLKDLSPCLSKVHREVGAREKELTHQVHSEILVRCLEQVKTL APILICSMKVYIHIVEQQ-GRGAEEAAENRNYLAARMSDELQEIIRVLQLTTYDEDTSEL -DNLTVLKKLSNAISNKMEQANEWLSNPYALRGGVGEKALRQVID--------------- ------------------------------------------------------------ ------------------------------------NATEISERCL-PQDSYPIRKLADE VTAMANTLCELRQEGKGQSPQAESLVRGIR---DRMGEL------KSLVHQAVLGVDKAG VQQTAHTIQGRLEQAVKWLQHPEINDGGLG-ERAINLIVEEGRKVAEGCPG-HQKAEIQQ LCDEVERLKRQ-------AAGSGPAAKQAAKQLTQKLYELKAAIQNALVNRIVQDFMDVS TPLKQFTEAVLQPEGTPGREQNFNQKSNNLQAFSDRASKTSRMVAAGGACGNKKIAEILL SSAAQVDSLTPQLISAGRIRMNYPGSKAADEHLQNLKQQYADTVLRMRTLCDQATDPADF IKTSEEHMQVYAKLCEDAIHARQPQKMVDNTSNIARLINRVLLVAKQEADNSEDPVFTER LNAAANRLERSLPAMVGDAKLVATNIADPAAAAAWKNSFQRLLGDVREVRDAIAP-PQPP ----------PLPTSLPPPIPELSALHLSNQNA---------------ERAPPRPPLPR- -EGLAPVRPPPPETDDED------------------------------------------ --------------------------------------EGVFRTMPH-ANQPILIAARGL HQEVRQWSSKDNEIIAAAKRMAILMARLSELVL----SDSRGSKRELIATAKKIAEASED VTRLAKELARQCTDRRIRTNLLQVCERIPTIGTQLKILSTVKATMLGAQG---------- --SDEDREATEMLVGNAQNLMQSVKETVRAAEGASIKIRSDQTSNRLQWVRRQPWYQY >XP_038053446.1 vinculin-like isoform X5 [Patiria miniata] ------------------------------------------------------------ ----------------------------MPTTSYRTKTIHSILDPVAQQVGHLVILHEQA E-DGNAMTDLTSPIKIVDQAVSNLVAVGKQTASTSKDEILRREMPPTFTQVERSSGLLVE ASALLKAD---------PYSVPARKKLIEGARGILQGTSDLLFVFDESEVRKIVKICEGV LQLLAVSEVVDTMQDILTFVQALTPGVTNMNSQVSARREELINASHAAQLAQHSEQFQKL IPLLVSSMKIYVTILEQG-KPGKQEAWENRTYVASKMIYHIQEIIRVLQ--AVDDDSFRV -DNVTGLRAAQNHIKNNMDKAMGWLADPNALAGGMGEKAVRRILE--------------- ------------------------------------------------------------ ------------------------------------DAKKVAGGLDGP-KKAEIEQAIDE ITAMVNELSDLRAKGLGNSPRALELAHALGGEHGKLANL------ERQINAAIAEILKSS MGKMAYTAGGKLAQAKEWLSNPGADDKGVG-YRAIKDIISTGRQIAGTCDDLGQRNDLLR LCNEAESLNDHLRDLCKKGQGNTPQAEATAKKLSEKLGQLNDKMTEIVMGQVSSDFLDPM SAVNKMYEAALAPEGAPHREANFTSKAQIFLESSNKAADTAARFAGIAD-ADRDTVDQIH RLSNQVKELTPQVVSAARIVLMNPNNKVAAAHLDVMKNDWEGAMKELDAKLTSSLDVPAF MKASEESMKKQTELAVAAVHQRNPQTYASCISNIALRGKNMVKVAKREAENSEDPEFQHK VDSASDQVNNCIPPTVTTGKQLMQDMANPDKMANWQDANSKLLDSVGNVRQAFVM-SQ-- -----------------PPTDAMSSLSL--------------------ENAPPRPPLPQ- -GEVPPPRPPPPEEETEA------------------------------------------ ----------------------------------------HFHEAPP-SNQPIMKAAYDL HLETQKWSSQGNDLVAAAKKMAILMAQMSKHVR----GEG-GSKKDFIMCARMIAKQSGE VTRLANIIADQCTDKRIRLNMKQVIERIPTFSTQLKILTTVKATMLGAQD---------- --PEKDEEATEMLIGNAQNLMQAVKESVRASEAASIKIRTD-AGLKLRWVRRNPYAY- >NP_741437.1 Vinculin [Caenorhabditis elegans] ------------------------------------------------------------ ----------------------------MPV--FHTKTIENILEPVAQQVSRLVILHEEA N-DGNAMPDLTGPVGMVSRAVGNLIQVGYDTCDHSDDRILQQDMPPALQRVEGSSKLLEE SSYSLKHD---------PYSVPARKKLIDGARGILQGTSALLLCFDESEVRKIIRVCRKA NDYVAVSEVIESMADLQQFVKDISPVLHDVTNDVNLRQQELTHQVHREILIRCMDSIKVI APILICSMKTSIELGTPHPRQGHAEAIANRNFMSQRMTEEMNEIIRVLQLTTYDEDEWDA -DNVTVMRKALSAAKSLLTAALDWLADPHARSGAVGEKAIRRICE--------------- ------------------------------------------------------------ ------------------------------------YADRISARAL-PEDAQSIKRSIFE ITSFTDELCNLRNNGQ---PDRENLAAQTA---RRLKDLVGSQNSSGLMGDALQNAQRHG GANPAHTAAGRLEQALRWLDNPGLDDGGLG-LQALRLLTADARKLADRLNP-QDRNRLLG LCSDIDRLAAQLADLERRGLGNSPEAHQIRNQLKNALRDLGDFMRRVLTDRVVDDFADIT TPLKQFVEAVHADPYDPNREQNFVDKSQRLTDHSQSMTTTARLVASCGPSKSKKTVEAIL DTAEKVEQLTPQLVNAGRVRLHNPGSE---QHFENIHKQYADALHRLRSHVDDAIDTGEF VRASETAMRRYTNHCEGAINGADAHGLVNNSSQIARLGNRVLMTAQNEADNSEEPSFVSR VRNAADQLHNAIPPMVNNAKQIAQNPHDQYAAQNWRGTNDHLLNSVRAVGDAITGVPMSN GRHSSYQESISRASPYNPPPPSSQVIRSVNASPPTAPIIHNKMIIREDIPAPPRPPPPV- -ELSPPPRPPPPPEYDEE----------------------EETRAFWER----------- ------------------------------------------YPLPQASHQPMLAAAHNL HNELKQWSSQENDIVAAAKRMAILMARLSQLVR----GEG-GTKKDLINCSKAIADSSEE VTRLAVQLARLCTDIKMRTALLQVSERIPTIATQLKVLSTVKATMLGSAS---------- --SEEDDEAMQQLVHNAQNLMQSVKDVVRAAEAASIKIRTN-SGLRLRWLRKPMWSNF
BMGE Cleaned alignment of selected proteins >sp|P18206|VINC_HUMAN Vinculin OS=Homo sapiens OX=9606 GN=VCL PE=1 SV=4 FHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGSSPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGKLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGIPAAEVGIGVVAEADADAAGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >sp|P18206-2|VINC_HUMAN Isoform 1 of Vinculin OS=Homo sapiens OX=9606 GN=VCL FHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGSSPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGKLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEAR-------------------------------------------------------------------KWSSKGNDIIAAAKRMALLMAEMSRLVRGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >sp|P18206-3|VINC_HUMAN Isoform 3 of Vinculin OS=Homo sapiens OX=9606 GN=VCL ----------------------------------------------------------------------MPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASK-----VRVLSGEISKI---------PNSP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WL--------GV--------------------------LIGTC---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LILYLVIFVA----------------------------------------------------------------------------------------------------------------------------- >NP_033528.3 vinculin [Mus musculus] FHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEIAALTSKLGDLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKAQMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVISAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEAR-------------------------------------------------------------------KWSSKGNDIIAAAKRMALLMAEMSRLVRGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_038949159.1 vinculin isoform X1 [Rattus norvegicus] FHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVGKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEIAALTSKLGDLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLAAQLADLAARGEGESPQARALASQLQDSLKDLKTQMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGAANKSTVEGIQASVKTARELTPQVISAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGLPAAQVGIGVVAEADADAVGFPFPSDMEDDSEPELLLVPANQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_040558242.1 vinculin isoform X1 [Gallus gallus] FHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVSAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVRAAQMLQADPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNTKSQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALALIDSKMNQAKGWLRDPNAPPGDAGEQAIRQILDEAGKAGELCAGKERREILGTCKTLGQMTDQLADLRARGQGATPMAMQKAQQVSQGLDLLTAKVENAARKLEAMTNSKQAIAKKIDAAQNWLADPNGGSEGEEHIRGIMSEARKVAELCEEPKERDDILRSLGEISALTAKLSDLRRHGKGDSPEARALAKQIATSLQNLQSKTNRAVANTRPVKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGRRLANVMMGPYRQDLLAKCDRVDQLAAQLADLAARGEGESPQARAIAAQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPSDTPNREEVFEERAANFENHAARLGATAEKAAAVGTANKTTVEGIQATVKSARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANMQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEHLHLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEAINQPMMMAARQLHDEARKWSSKPVNEAAEAGVDIDEEDDA-DVEFSLPSDIEDDYEPELLLMPTNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGNKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_020927737.1 vinculin isoform X1 [Sus scrofa] FHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPTASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGNPAAKVGIGVVAEADADAVGFPVPSDMEDDYEPELLLMPSSQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_009457029.1 vinculin isoform X1 [Pan troglodytes] FHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGSSPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGKLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGIPAAEVGIGVVAEADADAAGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_038347906.1 vinculin isoform X14 [Canis lupus familiaris] FHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVAELRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPSREEVFDERAANFEHHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEQLRLADELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGNRAAEVGIGVVAEADADAVGFPVPPDMEDDFEPELLLMPSNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >NP_001178299.1 vinculin [Bos taurus] FHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLGDLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGNPAAKVGISVVAEAEADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_019473128.1 vinculin [Meleagris gallopavo] --------------------------------------------------LVMVGKETVQTTEDQILKRDMPPAFIKVENACTKLVRAAQMLQADPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNTKSQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALALIDSKMNQAKGWLRDPNAPPGDAGEQAIRQILDEAGKAGELCAGKERREILGTCKTLGQMTDQLADLRARGQGATPMAMQKAQQVSQGLDLLTAKVENAARKLEAMTNSKQAIAKKIDAAQNWLADPNGGSEGEEHIRGIMSEARKVAELCEEPKERDDILRSLGEISALTAKLSDLRRHGKGDSPEARALAKQIATSLQNLQSKTNRAVANTRPVKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGRRLANVMMGPYRQDLLAKCDRVDQLAAQLADLAARGEGESPQARAIAAQLQDSLKDLKARMQEAMTQEVSDIFSDTTTPIKLLAVAATAPSDTPNREEVFEERAANFENHAARLGATAEKAAAVGTANKTTVEGIQATVKSARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANMQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEHLHLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEAINQPMMMAARQLHDEARKWSSKPVNEAAEAGVDIDEEDDA-DVEFSLPSDIEDDYEPELLLMPTNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGNKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_002718451.2 PREDICTED: vinculin isoform X1 [Oryctolagus cuniculus] FHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKVDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKAQMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGIRAAEVGIGGVAEADADAVGFPVPSDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_024109838.1 vinculin isoform X2 [Pongo abelii] FHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGSSPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTTSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGKLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGIPAAEVGIGVAAEADADAAGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_003813044.1 vinculin isoform X2 [Pan paniscus] FHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGSSPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGKLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGIPAAEVGIGVVAEADADAAGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_019668863.1 vinculin isoform X1 [Felis catus] FHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVAELRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPSREEVFDERAANFEHHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKRGNPAAEVGIGVVAEADADAVGFPVPPDMEDDYEPELLLMPSSQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_027818089.1 vinculin isoform X1 [Ovis aries] FHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLGDLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAQCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGNPAAKVGISVVAEAEADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_004049661.1 vinculin isoform X2 [Gorilla gorilla gorilla] FHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGSSPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGKLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGIPAAEVGIGVVAEADADAAGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_043332427.1 vinculin isoform X2 [Cervus canadensis] FHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGNPAAKVGISVVAEAEADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_043332426.1 vinculin isoform X1 [Cervus canadensis] FHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGNPAAKVGISVVAEAEADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >KAF4018928.1 hypothetical protein G4228_011024 [Cervus hanglu yarkandensis] FHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGNPAAKVGISVVAEAEADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_018094934.1 vinculin isoform X1 [Xenopus laevis] FHTKTIESILEPVAQQISHLVIMHEEGEVDGKAIPELTAPVAAVQAAVSNLVRVGKETVQTTEDQIMKRDMPPAFIKVENACAKLVQAAQMLNADPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVESMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKDLLPVLISAMKIFVTTKSSRSQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALALIDSKINQAKGWLRDPNAPPGDAGEQAVRQILDEAGKVGELCAGTERKDILGTCRTLGQMTDQVSDLRSRGQGATPIAMQKAQQVSQGLDVLTSKVKNAAHKLEALTNSKQAIGKKIDAAQSWLADPNGGPEGEENIRTILAEAKKIADLCEDPKDKEDILRSLGEIAALTAKLTDLRRQGKGDSPEARALAKQIATSLQNLQTKVNRAVANSRPVKAAVNMDGKVEQAQRWIDNPSVDDRGVGQAAIRSLVAEGRRLANSMTGPFRQDMIAKCDRVEQLAGQLAELALRGEGDTPLAQAVAAQLQEALKDLKGKMQEAMTQEVSDVFSDTTTPIKLLAVAATSPPDAPNRDEVFEERAANFENHSARLGATAEKAAAVGSANKATVEGIQAAVKSARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTRSLLDASEEAIKKDIDKCKVAMANMQPQMLVAGATSIARRANRILLVAKREMENSEDPKFRDTVKNASDELSKTISPMVMEAKAVAGNISNPALQKGFLDSGYRILGAVAKVREAFQPEFPPPPPDLDQLRLSDDAAPPKPPLPEGEVPPPRPPPPDEKDEEFPEQKVGEVVNQPMMVAARQLHDEARKWSSKSPREAVISEVEQEEEEEA-SVEFALSSDIEDDYEPELLLVPEGQPVNQPMLAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGNKRALIQCAKDIAKASDEVTKLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWARKTPWYQ >XP_005156897.1 vinculin isoform X1 [Danio rerio] FHTKTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTSPVAAVQAAVSNLVRVGKETVQTTEDKIMKRDMPSAFIKVENACAKLVEAAQMLRTDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLITYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVTSMNTVKELLPVLISAIKIFVTTKCTKSHGVEEALKNRNYTFDKMTAEINEIIRVLQLTSWDEDAWANKDTEAMKRALALIESKMGQAKGWLRDPNALPGDPGEHALRQILDEAGKVGELCAGKERREILGTAKTLGQMTDQVSDVRARGQGATPMGMQKAQQVAQGLDILVGKVENAARKLEALTNAKQAIAKRIDNAQSWLADPNGGPEGEENIRALLAEAKRIADLCEDPKERDDILRSIGEIAGLTARLVELRRIGKGDTPEARALAKQIGTALQNLQAKTNRAVANMRPAKAAVTLEGKMEQALRWINNPGVDDHGVGQAAIRGLIAEGRRLASSLPGPYRQELLAKCEQVEQLMMQLADLAARGEGESPQARAVAAHLLEAIKDLKAKMQEAMTQEVSDVFSDTTTPIKLLAVAATAPLEAPNREEVFEERASNFENHASRLGATAEKAAAVGTANKSTVEGIQAAVKSARDLTPQVTSAARILLKNPGNQAAYEHFDTMKNQWIDNIEKMTSLVDEAIDTKSLLDASEEAIKKDIDKCRVAMANVQPQMLVAGATSIARRANRVLLVAKREVENSEDPKFRELVKAASDELGRTISPMVMAAKGVAGNIQDPGLQKGFLDSGYRILAAVGKVREAFQPDFPPPPPDLDQLHVNDDQAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEMVSEPMMVAARSLHDEARKWSSKPEFEAAEAEVDIDDEDEF--------TDNEDDYEPELLLMSSNQPVNQPILAAAQSLHQEARKWSSKGNDIIGAAKRMALLMAEMSRLVRGNKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISEEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_020565294.1 vinculin isoform X4 [Oryzias latipes] FHTKTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTVPVAAVQAAVSNLVRVGKETVQTTEDQVMKRDMPPAFIKVENSCSKLVQAAQMLKSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLITYTKNLGPGMTKMSKMIEERQQELTHQEHRQMLVSSMNTIKELLPVLISAIKIFVATKSTRGAGVEEAERNRRFTFEKMSTEINEIIRVLQLTTWDEDAWANKDMEALKRSLALIESRMAQAKSWLKDPHGQPGDSGELALRVILDEAGKVGELCAGKERKDVLATTKALGQMTDQIADLRARGQGPTPGCVQRAGQCSQGLDLLYGKVDSAARRLEALISAKQAIARKLDAAQAWLADPNGGPEGEENIRALLAEAKRIADLCEDPKERDDILRSISEIVGLTTRLAELRKQGKGDSPEARALAKQIGGALLTLQSKTNRAVANMRPAKPAVTLEGKMEQALRWVNNPGVDDRGVGQAAIRGMVGEGRRLAAGLLGPYRQDMIGRCDRTEGLMAALADMAGRGEAEAPHARVTAAQLQDSLKDLRQHMQEVMTQDVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAGNFETHASRLGATAEKAAAVGTANKSTVEGIHATVKHARELTPQVTSAARILLRNPGNKAAYEHFDTMKNQWIDNVERLTGLVDEAIDTKSLLDASEEAIKKDIDKCRVAMANVQPQMLVAGATSIARRANRVLLVAKREVENSEDPRFRDCVKHASDILSHTISPMVMDAKAVAGNIQDKALQKAYLDSCLRILAAVGKVREAFQPDFPPPPPDLDQLHVSDEQAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVLSEPMMVAARQLHDEARKWSSKPEDEEAIEEREVDDEDEF--------TDGEDDYEPELLMMPSNQPVNQPILAAAQSLHQEARKWSSKGNDIIAAAKRMALLMAEMSRLVRGNKRALIQCAKDIAKASDEVTRLAKEVAKQCTDRRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISEEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_030297248.1 vinculin-like isoform X4 [Sparus aurata] FHTKTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTVPVAAVQAAVSNLVRVGKETVQTTEDQVMKRDMPPAFIKVENSSSKLVQASQMLKADPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLITYTKNLGPGMTKMSKMIEERQQELTHQEHRQMLVNSMNTVKELLPVLISAIKIFVTTKSSRGAGVEEAERNRRFIFEKMSAEINEIIRVLQLTTWDEDAWANKDMEALKRSLALIESKMAQAKGWLKDPHGQPGDPGEVALRVILDEAGKVGELCAGRERKDILATAKALGQMTDQIADLRARGQGPSPGCVQRAGQCSQGLDLLFGKVDCAARRLEALINAKQAIARRLDAAQAWLADPNGGPEGEENIRALLAEAKRIADLCEDPKERDDILRSISEIAGLTARLVELRKQGKGDSPEARALAKQIGAALLTLQSKTNRAVANMRPAKPAVTLEGKMEQALRWANNPGVDDRGVGQAAIRGMVGEGKRLAGGLLGPYRQDMIGRCDRTEALMTSLADMANRGEAEAPHARATAAQLQDSLKDLRQHMQEVMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNRAEVFEERAGNFEAHAGRLGATAEKAAAVGTANKSTVEGIHAAVKHARELTPQVTSAARILLKNPGNKAAYEHFDTMKNQWIDNVEKLTGLVDEAIDTKSLLDASEEAIKKDIDKCRVAMANVQPQMLVAGATSIARRANRVLLVAKREVENSEDPRFRDTVKHASDILSHTISPMVMDAKAVAGNIQDKALQKAYLDSCLRILAAVGKVREAFQPDFPPPPPDLDQLHVSDEQAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKVGEVLSEPMMVAARQLHDEARKWSSKPEDEEAVEEREVDDEDEF--------TDGEDDYEPELLMMPSNQPVNQPILAAAQALHQEARKWSSKGNDIIAAAKRMALLMAEMSRLVRGNKRALIQCAKDIAKASDEVTRLAKEVAKQCTDRRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISEEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >OWK07868.1 VCL [Cervus elaphus hippelaphus] ------------------------------------------------------------------------------------------MLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPNASP-----------------------GKERREILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILR-------------------KGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGNPAAKVGISVVAEAEADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLL-----------QLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_015799676.1 PREDICTED: vinculin-like isoform X4 [Nothobranchius furzeri] FHTKTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLSVPVAAVQAAVSNLVRVGKETVQTTEDQLMKRDMPPAFIKVENSSSKLVQAAQMLKADPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLITYTKNLGPGMTKMSKMIEERQQELTHQEHRQMLINSMNTVKELLPVLISAIKIFVATKSSRGAGVEEAERNRKFTFEKISAEMHEIIRVLQLTTWDEDTWANKDMEALKRSLALIESKMAQAKSWLKDPHGQPGDPGEVALRVILDEAGKVGELCAGKERKDILATTKALGQMSDQIADLRVRGQGPTPGCVQRAGQCSQGLDLLFGKVDSAARRLEALINAKQAIARRLDAAQAWLADPNGGAEGEENIRALLAEAKRIADLCEDPKERDDILRSINEIAGLAARLVELRKQGKGDSPEARALAKQIGAALLNLQSKTNRAVANMRPAKPAVTLEGKMEQALRWVNNPGVDDRGVGQAAIRGMVGEGKRLAGGLLGPYRQDMIGRCDRTEALMTSLADMANRGEAEAPHARATAAQLQDTLKDLRQHMQEVMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFEERAGNFETHAGRLGATAEKAAAVGTANKSTVEGIHAAVKHARELTPQVTSAARILLKNPGNKAAYEHFDTMKNQWIDNVERMTGLVDEAIDTKSLLDASEEAIKKDIDKCRVAMANVQPQMLVAGATSIARRANRVLLVAKKEVENSEDPRFRDTVKHASDILSHTISPMVMDAKAVAGNIQDKALQKAYLDSCLRILAAVGKVREAFQPDFPPPPPDLDQLHVNDEQAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKASEVLSEPMMVAARQLHDEASKWSSKPEDEEAVEEREVDDEDEF--------TDGEDDYEPELLMMPSNQPVNQPILAAAQSLHQEARKWSSKGNDIIAAAKRMALLMAEMSRLVRGNKRALIQCAKDIAKASDEVTRLAKEVAKQCTDRRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISEEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_021139948.1 vinculin [Columba livia] FHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLIYSEILNLKYDFFLPQVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQADPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKSQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALALIDSKMNQAKGWLRDPNAPPGDAGEQAIRQILDEAGKAGELCAGKERREILGTCKTLGQITDQLSDLRARGQGATPMAMQKAQQVSQGLDLLTAKVENAARKLEAMTNSKQAIAKKIDAAQNWLADPNGGSEGEEHIRGILAEARKVAELCEEPKERDDILRSLGEISALTAKLSDLRRHGKGDSPEARTLAKQIATALQNLQSKTNRAVANTRPVKAAVHLEGKIEQAQRWIDNPTVADRGVGQAAIRGLVAEGRRLANVMMGPYRQDLLAKCDRVDQLAAQLADLAARGEGESPQARAIAAQLQDSLKDLKTRMQEAMTQEVSDIFSDTTTPIKLLAVAATAPSDAPNREEVFEERAANFENHAARLGATAEKAAAVGTANKTTVEGIQATVKSARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANMQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKVASDELSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEQLHLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEAINQPMMMAARQLHDEARKWSSKPDNEAAES-VDIDDEDDA-DVEFTLPSDTEDDYEPELLLMPTNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGNKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_005699280.1 PREDICTED: vinculin isoform X1 [Capra hircus] FHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPNASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLGDLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAQCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGNPAAKVGISVVAEAEADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_025068505.1 vinculin isoform X1 [Alligator sinensis] FHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQADPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNCKSQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALALIDSKMNQAKGWLRDPNAPAGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGATPVAMQKAQQVSQGLDLLTAKVENAARKLEAMTNSKQAIAKKIDAAQNWLVDPNGGSEGEEHIRGIMAEARKIAELCEEPKERDDILRSLGEISALTAKLSDLRRHGKGDSPEARALAKQIATSLQNLQSKTNKVVANTRPVKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGRRLANVMMEPYRQDLLARCDRVEQLAAQLADLAARGEGESPQARAIAAQLQDSLKDLKTRMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNRDEVFGERAANFENHAARLGATAEKAAAVGTANKTTVEGIQATVKSARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDDLSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEQLHLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPDNEATEAGVDIDEEDDADDAEFTLPSDIEDDYEPELLLIPSNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_006273854.1 PREDICTED: vinculin isoform X2 [Alligator mississippiensis] FHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQADPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNCKSQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALALIDSKMNQAKGWLRDPNAPAGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGPTPMAMQKAQQVSQGLDLLTAKVENAARKLEAMTNSKQAIAKKIDAAQNWLADPNGGSEGEEHIRGIMAEARKIAELCEEPKERDDILRSLGEISALTAKLSDLRRHGKGDSPEARALAKQIATSLQNLQSKTNKVVANTRPVKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGRRLANVMMEPYRQDLLAKCDRVEQLAVQLADLAARGEGESPQARAIAAQLQDSLKDLKTRMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNRDEVFGERAANFENHAARLGATAEKAAAVGTANKTTVEGIQATVKSARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDDLSKTISPMVMDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEQLHLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPDNEATEVGVDIDEEDDADDAEFTLPSDIEDDYEPELLLIPSNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_020770146.1 vinculin isoform X1 [Odocoileus virginianus texanus] FHTRTIESILEPVAQQISHLVIMHEEGEVDGKAIPDLTAPVAAVQAAVSNLVRVGKETVQTTEDQILKRDMPPAFIKVENACTKLVQAAQMLQSDPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLTVAEVVETMEDLVTYTKNLGPGMTKMAKMIDERQQELTHQEHRVMLVNSMNTVKELLPVLISAMKIFVTTKNSKNQGIEEALKNRNFTVEKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALASIDSKLNQAKGWLRDPSASPGDAGEQAIRQILDEAGKVGELCAGKERREILGTCKMLGQMTDQVADLRARGQGASPVAMQKAQQVSQGLDVLTAKVENAARKLEAMTNSKQSIAKKIDAAQNWLADPNGGPEGEEQIRGALAEARKIAELCDDPKERDDILRSLGEISALTSKLADLRRQGKGDSPEARALAKQVATALQNLQTKTNRAVANSRPAKAAVHLEGKIEQAQRWIDNPTVDDRGVGQAAIRGLVAEGHRLANVMMGPYRQDLLAKCDRVDQLTAQLADLAARGEGESPQARALASQLQDSLKDLKARMQEAMTQEVSDVFSDTTTPIKLLAVAATAPPDAPNREEVFDERAANFENHSGRLGATAEKAAAVGTANKSTVEGIQASVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTKSLLDASEEAIKKDLDKCKVAMANIQPQMLVAGATSIARRANRILLVAKREVENSEDPKFREAVKAASDELSKTISPMVVDAKAVAGNISDPGLQKSFLDSGYRILGAVAKVREAFQPDFPPPPPDLEQLRLTDELAPPKPPLPEGEVPPPRPPPPEEKDEEFPEQKAGEVINQPMMMAARQLHDEARKWSSKPGNPAAKVGISVVAEAEADAVGFPVPPDMEDDYEPELLLMPSNQPVNQPILAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGTKRALIQCAKDIAKASDEVTRLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGFTLRWVRKTPWYQ >XP_040176600.1 vinculin isoform X1 [Rana temporaria] FHTKTIESILEPVAQQISHLVIMHEEGEVDGKAIPELTTPVAAVQSAVSNLVRVGKETVQTTDDQMMKRDMPPAFIKVENACAKLVQAAQMLHADPYSVPARDYLIDGSRGILSGTSDLLLTFDEAEVRKIIRVCKGILEYLAVAEVVESMEDLVTYTKNLGPGMTKMAKMIDDRQQELTHQEHRVMLVNSMNTVKDLLPVLISAMKIFVTTKSSRSQGVEEALKNRNFTVDKMSAEINEIIRVLQLTSWDEDAWASKDTEAMKRALAHIGSKMNQAKGWLRDPNAPPGDAGEQAVRQILDEAGKVGELCAGKERRDILGTCKALGQITDQVADLRARGQGATPTAMQKAQQVSQGLDLLTAKVENAARKLEALTNSKQAIGKKIDTAQSWLADPNGGPEGEETIREILAEAKRIAELCEDPKDREDILRSLGEIAACTAKLSDLRRQGKGDTPEARALAKQIGTSLQNLQTKVNRAVANSRPVKAAVNMEGKVEQAQRWIDNPSVDDRGVGQAAIRGMVAEGRRLANSMIGPYRQDMMARCDCVEQLAGQLAELAARGEGDTPHARAVAAQLQDALKDLKAKMQEAMTQEVSDVFSDTTTPIKLLAVAATSPPDAPNREEMFDDRAANFESHAARLGATAEKAAAAGSANKATVEGIQATVKTARELTPQVVSAARILLRNPGNQAAYEHFETMKNQWIDNVEKMTGLVDEAIDTRALLDASEEAIKKDIDKCKVAMANMQPQMLVAGATSIARRANRIMLVAKREVENSEDPKFREAVKNASDDLSKTISPMVLEAKAVAGNISDPALQKGFLDSGFRILGAVAKVREAFQPDFPPPPPDLEHLRLTDEAAPPKPPLPEGEIPPPRPPPPDEKDEEFPEEKVGEV-NEPMMVAARQLHEEARKWSSKSPTEAVVSEVEQEEEEEA-SVEFVL-SDVEDDYEPELLLVPEGQPVNQPMLAAAQSLHREATKWSSKGNDIIAAAKRMALLMAEMSRLVRGNKRALIQCAKDIAKASDEVTKLAKEVAKQCTDKRIRTNLLQVCERIPTISTQLKILSTVKATMLGRTNISDEESEQATEMLVHNAQNLMQSVKETVREAEAASIKIRTDAGITLRWARKTPWYQ >XP_039272784.1 vinculin-like isoform X1 [Styela clava] FHTKTIQMILEPVAEQVSTLVLIHEQGK-DGNQMPDLINPILTVKAAVSNLVKVGKDQIKDTKDEILKLDTPPALEKVETSADMLVQASQLLSIDPEGMEGRKKLIAGSRGILQGTSDLLLVFDEAEVRRICKVCRNVRDYLNQSSIVAGMEDLVVFVKSLTPGTTTLARMIGDRCKDLTNQNHVAALTEEMDQVKAYIPGLISSLKAFVQTVDKPGKAQEAAIGNREYYTTQISERITEIIRLLQLVSTDDANTDPLNVLQLKQTQQKMARKMQPAKNWLNNPNAPAGGPGELALREILDGAKEIGNQAGGPLGDKILGTTAHLGTLTDQLSDLRANGKGNSAEAKQIATQINGELDQLMEDVDDAIEAMDKLAMAHSGMVKTMPAAREWLANLSAKPEGAEHVHNVTKAGREIAMGLGSCKDRDDIIQLCDEIDDMMQKLEEFRTLGLGDTPEAVALSKSIADKLTALNAKVAKALAS---KKSVATLDSKMEEIARWLDNPGVKDGGRGARSTKSLLGDARQIAARISDNARFALLKNVAECDRLLKDLEHLIQTGRGDSKEAKEIAKKLQKKLEEVKKQMKDALVRAVADEFADTTTSLKQLHSAAIAPLDTLNREENFEGKALTFQSQSTRLADLARQAVGASDVSQEKVDEVKKKAVRIEGLTPQVINAGRIVLSNPENKTSLEHFETLKQDWTRNMDELTDMVDDSVDFATFMDASEESMRREHEACVKAVKLDKPADALPLAGNISRRAHRILMTGKREMQNTDDPQYVEQLRKNLNAIQQQLDPTLKSARTYAGAPANRKNQNDFIDNEDKLIQAVSNLQKTVKA----EIIEKEKQRKALEEPPPVPPMPVTELPPPVPPPPEEE-------------------------------------------------------------------------FPEVE-SNQPIMVAAKELHEEAKKWESTGNNIIAAAKKMALLMAKMSRLVDGSRSELIQCAKDIAKASNDVTKYAKEVATQCTDKRIKTDMMKTLDRLPTISTQLRILSTVKATTLGNPSQKEEDAEQATEMLVHNAQNLMQSVKETVRYAEAASIRIRTDAGLTMRWVRKDN--- >CAE1284850.1 VCL [Sepia pharaonis] FHTKTIEGILEPVAQQVSKLVILHEEAE-DGNAMPDLARPVQAVKLAVDNLVKVGYDTINSSEDQILKQDMPPALHRVEDASVLLLEASDMLRDDPFSAPARKKLIEGSRGILQGTSSLLLAFDESEVRKIIRVCKNVLEYLAITEVVDKMEDLVTYVKNLSPVLTKIIKEVDAREKELTHQVHRDMLIRSLDQVKNLTPVLISGVKIFITAKET-STGFAEAQNNRDFVVRKMSDEIHEIIRVLQLTTYDEEEWDADDLTVMKKAQCAIEGKLQQAADWLQDPAALVGSAGDKALHQILE-------------------------------------------------------------------------------------------------------------DARKIAERCSNPNERDSILRTVGDIESMANTLAELRQQGKGSSPQAMSLAREIQNKLRDLTQLTQNGIVNTERRKPAPTVSGKVEQAQRWLVNPGLDDKGLGEQATRMVVAEGRKVAESLTGPQRAELLRLCDETEILTNQLSDLIRRGQGNSPQAQACARHLSEKLHALKNKIGEGLVNQVAEDFIDMTTPLKQLSDAAMAPLGVPGREQNFDEKARNFLTQSSKLSDTANMVATAGGCNKKTVEAIFATSAQANDLSPQVVNAAKIVLINPENQAAVDHFDLLKKQWTENMERLRTLVDEATDTEAFIRATEVGIKKDTEKVEDGIRAVSPQMVVANASNIARRANRVLQVAQQEAENSEDPAFVEKVNQSSDILKSSITPMVQQAKAVSMNPKDPAAANNWRKENNNLIAAVGQVRESVTVQPFPQPPDMSQLHISD--APPRPPLPH-ETVPPRPPPPETDDED------------------------------------------------------------------ESA-FPMPQ-ANQPIMMAAHDLHMETKQWSSKDNEIIVAAKKMALLLAKLSHLVSTCKWIW------------------------CTAHKM----------------------------------------------------------------------------------------- >XP_030848750.1 vinculin isoform X6 [Strongylocentrotus purpuratus] FHTKTIEAILDPVAQQVSQLVILHEEAQ-DGNAMPDLSRPVMAVSAAVQNLVKVGRDTANSTDDKILKQEMPPAFQGVEQSATKLYEAAMMLKEDPYSSPARKMLIDGARGILSGTSDLLLCFDQSEVRKIVRVAKGVLEYLAVSEVVESMEDLVTFVKNLSPGMANLANKVTGRSKELTHTAHANGLVNHTENLKRTTPILVSSIKIFVTTLQKGGAGRDEAQQNRNFIIGRMSHDVNEIIRILQLTSADDDDWSMDDLTIMKKSLLNITNQMNMAQTWLANSNAEPGGLGEKAVRDILR-------------------------------------------------------------------------------------------------------------DARRVADRLEGP-QREHLLATINEIEVMMNELCALRAKGQGNSPRALQLAKQIAEKLGYLHQEVDFAVKDAVKTRTAYTLAGKVEQAQKWLRNPAQDDKGVGRRAVAGIVAQGRKVAQNLSEPERGELLRLCDEVESLSQQITDLVNRGQGNSPQCLDAARRLAERLPSLQKMIENALAKEVAEVFMDTTTPLKELERAAKAPADDPNRQQTYTSKATIFLTHANKISDTAKLVAEAGANDRPLVEELNNKAQEVKDLAPQVVAAGKVLLLNPGEQTAVSHFDELKREYMGKVETLTDLVDQAVDTVEFVKASEEAIKRDSEKVAQAIQQNDPNVIAAKASSIARRAQRVAVVASKEAANSEDPKFVQDVSRAANQLSGDIPPSVTAAKGVTLNPADRNAQDKWFTANKQVQSDVGDVRQALTVPIMPPPPDMSRLQLE-EAAPPRPPLP-GDVPPPRPPPPEDTSLP----------------------------------------------------------------------LPEQG-SHQPIMQAAYDLHVETEQWSSKDNDLIAAAKRMAQLMAAMSKHVSTSKKELIEIAKKIAQASLEVVRLAGEIAAQCTDKRMKNNLLQVCERIPTISTQLKILSTVKAVMLGSQE--SEEDMEATEMLVGNAQNLMKAVKETVRAAKAASIKIRTDAGYKMRWVRQRPWYQ >XP_031557163.1 vinculin-like [Actinia tenebrosa] FHTKTIESILDPVAQQVSQLVIFHEEGE-DGRAMPDLSAPIKAVGAAVANLVKVGQQTAANSKDKILRQEMPLAFTRVEESSTFLVEAAKILKNDPYSSVARKKLIDGARGILSGTSALLLTLDEAEVRRILHVCKSLLEYFPVAEMVEEMTDLVTFVTNLTPGTTSLAKQVEERAEELTHHEHRDILKSCIGKIKHLVPLLISAMKAFVKT--PLGAGRAEAQENRNFIITKICAEITEIMRVLQLTSTEENKGD-DPLYDMKKAVSVFDSKFDKAREWIGEPTCDAGGLGDQAVRECIQ-------------------------------------------------------------------------------------------------------------QGRLMGSVCQDP-QKNKIQRCCDDLDRLMSELETLRSQGKGTTPRGLELSREVDKQLGVLRNLMDEAIHHQGIKKPANTFVGKMEQAQQWLANPSGDHTGLGEKAIRECINDARKIADKSSGPERMELLKLCNEVERLTDELADLKRRGLGNSPQAYALANKLSNKLDELHRQTQRAIANQVAQNFVDPTGQIKQLERAAKAPRGTPNREADFETKAGNFEHQANEMADTAFRFANNSSTRKKSLEDIRKTAQYMKELTPQVSHAAKVLLDNPDEPAAGEHFEKLKDEWVQETTKLANSIDSTADTLQLIEACEEAINRDVLACDNALSQENPQLVVAKTSNIARMAQRIAKLVNAEAENTEDPEFRAKLEQMSRNIQDVIAPLAIEAKSVVSNIKDKQGHERLRAAMRRVQRNVGEVRKVFIDPPPPPPPEMEDLSLHEERAPPRPPLPRTTSAPPRPPPPAMEPKI--------------------------------------------------------------DMNLQSM-LESPP-EDNRMAMAASNLHKEILKWEEQGNDMIQAAKRMAVLFAKMSKFMRHSKKELIQLAKEIATASKEIVKFGNRACQKCSDKRLKASMQQTIDRIPTISTQLKIVSTVKATMIGSQE--LEEDREATETLVGCAENLMSAVRQTVRETEAASVKMRTDAGLVMHWKKKQY--- >XP_026301464.1 vinculin isoform X3 [Apis mellifera] FHTKTIESILEPVAQQVSRLVILHEEAE-DGNAMPDLGKPVQAVSMAVANLVKVGKETINSSDDALLKQDMPAALQRVEGASRLLEEASAMLKQDPYSGPARKKLIEGSRGILQGTSSLLLCFDESEVRKIIRECKRVLDYLAVTEVIETMEDLVHFLKNLSPCLSKVSKEVSAREKELTHQVHREILVRCLEQVKTLAPILICSMKIFIHIISQGGKGAEEAAENRNYLSGRMSDELNEIIRVLQLTTYDEEEWDADQLTVLKKAQSAIESRIRAAYDWLDDGFALRGGLGEKSLRQIVE-------------------------------------------------------------------------------------------------------------QAQRLAERYLPPSQAESLQKLTSQIVTMTNALCELRQNEKGSTPQAEALARSIKEKTNELRSSIASAIIAADKTQTAHTVAGRLEQANKWLLNPQHDDKGLGQRAIALIIHEGKKVAEGLPGIHKAEILQLCDEVDNLSHQLGDLCAHGQGNTPRAQEIARQLSHKLYELKNRIQQAVVSRVVEDFIDITTPLKQFTDAVLTPEGSLGRDQNFNDKTHALQTFSNRATKTAKMVAAGGSGNKKLAEALTTSASQVESLTPQLINAGRIRMTYPDSKAADEHFENLRQQYADTIQRVRALCDEATDSGDFIRTSEEQMQKHSFLCEEAIAKSHPQKMVDNTAAIARLANRVILVAKQESDNSEDTAFIQRVNQATDILQNSVAPMVQDAKLVAININDNNAVSHWRESNRTLLSNVGQVRKAIVL----SPPEVSQLHLNDEVVPPRPPLPGGDIPPPRPPPPETDDED------------------------------------------------------------------E-MFMHAPQ-PNQPIMMAAHGLHQEVRQWSSKDNEIIAAAKKMAILMGRLSGLVRGNKRDLIACAKAIAEASQEVTRLAKELARECTDKRIRTNLLQVCERIPTIGTQLKILSTVKATMLGAQETGTEEDQEATDMLVGNAQNLMQSVKETVRAAECASIKIRTASGMKLRWVRRQPWYQ >NP_001284813.1 vinculin, isoform B [Drosophila melanogaster] FHTKTIESILDPVAQQVSRLVILHEEAE-DGNAMPDLSRPVQVVSAAVANLVKVGRDTINSSDDKILRQDMPSALHRVEGASQLLEEASDMLRSDPYSGPARKKLIEGSRGILQGTSSLLLCFDESEVRKIIQECKRVLDYLAVAEVINTMEQLVQFLKDLSPCLSKVHREVGAREKELTHQVHSEILVRCLEQVKTLAPILICSMKVYIHIVEQQGRGAEEAAENRNYLAARMSDELQEIIRVLQLTTYDEDTSELDNLTVLKKLSNAISNKMEQANEWLSNPYALRGGVGEKALRQVID-------------------------------------------------------------------------------------------------------------NATEISERCL-PQDSYPIRKLADEVTAMANTLCELRQEGKGQSPQAESLVRGIRDRMGELKSLVHQAVLGVDKQQTAHTIQGRLEQAVKWLQHPEINDGGLGERAINLIVEEGRKVAEGCPGHQKAEIQQLCDEVERLKRQ-------AAGSGPAAKQAAKQLTQKLYELKAAIQNALVNRIVQDFMDVSTPLKQFTEAVLQPEGTPGREQNFNQKSNNLQAFSDRASKTSRMVAAGGAGNKKIAEILLSSAAQVDSLTPQLISAGRIRMNYPGSKAADEHLQNLKQQYADTVLRMRTLCDQATDPADFIKTSEEHMQVYAKLCEDAIHARQPQKMVDNTSNIARLINRVLLVAKQEADNSEDPVFTERLNAAANRLERSLPAMVGDAKLVATNIADPAAAAAWKNSFQRLLGDVREVRDAIAPSLPPPIPELSALHLSNERAPPRPPLPREGLAPVRPPPPETDDED------------------------------------------------------------------EGVFRTMPH-ANQPILIAARGLHQEVRQWSSKDNEIIAAAKRMAILMARLSELVLGSKRELIATAKKIAEASEDVTRLAKELARQCTDRRIRTNLLQVCERIPTIGTQLKILSTVKATMLGAQG--SDEDREATEMLVGNAQNLMQSVKETVRAAEGASIKIRSDTSNRLQWVRRQPWYQ >XP_038053446.1 vinculin-like isoform X5 [Patiria miniata] YRTKTIHSILDPVAQQVGHLVILHEQAE-DGNAMTDLTSPIKIVDQAVSNLVAVGKQTASTSKDEILRREMPPTFTQVERSSGLLVEASALLKADPYSVPARKKLIEGARGILQGTSDLLFVFDESEVRKIVKICEGVLQLLAVSEVVDTMQDILTFVQALTPGVTNMNSQVSARREELINASHAAQLAQHSEQFQKLIPLLVSSMKIYVTILEQGKPGKQEAWENRTYVASKMIYHIQEIIRVLQ--AVDDDSFRVDNVTGLRAAQNHIKNNMDKAMGWLADPNALAGGMGEKAVRRILE-------------------------------------------------------------------------------------------------------------DAKKVAGGLDGP-KKAEIEQAIDEITAMVNELSDLRAKGLGNSPRALELAHALGGKLANLERQINAAIAEILKGKMAYTAGGKLAQAKEWLSNPGADDKGVGYRAIKDIISTGRQIAGTCDDGQRNDLLRLCNEAESLNDHLRDLCKKGQGNTPQAEATAKKLSEKLGQLNDKMTEIVMGQVSSDFLDPMSAVNKMYEAALAPEGAPHREANFTSKAQIFLESSNKAADTAARFAGIADADRDTVDQIHRLSNQVKELTPQVVSAARIVLMNPNNKVAAAHLDVMKNDWEGAMKELDAKLTSSLDVPAFMKASEESMKKQTELAVAAVHQRNPQTYASCISNIALRGKNMVKVAKREAENSEDPEFQHKVDSASDQVNNCIPPTVTTGKQLMQDMANPDKMANWQDANSKLLDSVGNVRQAFVM---PPTDAMSSLSL--ENAPPRPPLPQGEVPPPRPPPPEEETEA--------------------------------------------------------------------HFHEAPP-SNQPIMKAAYDLHLETQKWSSQGNDLVAAAKKMAILMAQMSKHVRGSKKDFIMCARMIAKQSGEVTRLANIIADQCTDKRIRLNMKQVIERIPTFSTQLKILTTVKATMLGAQD--PEKDEEATEMLIGNAQNLMQAVKESVRASEAASIKIRTDAGLKLRWVRRNPYAY >NP_741437.1 Vinculin [Caenorhabditis elegans] FHTKTIENILEPVAQQVSRLVILHEEAN-DGNAMPDLTGPVGMVSRAVGNLIQVGYDTCDHSDDRILQQDMPPALQRVEGSSKLLEESSYSLKHDPYSVPARKKLIDGARGILQGTSALLLCFDESEVRKIIRVCRKANDYVAVSEVIESMADLQQFVKDISPVLHDVTNDVNLRQQELTHQVHREILIRCMDSIKVIAPILICSMKTSIELGTPHRQGHAEAIANRNFMSQRMTEEMNEIIRVLQLTTYDEDEWDADNVTVMRKALSAAKSLLTAALDWLADPHARSGAVGEKAIRRICE-------------------------------------------------------------------------------------------------------------YADRISARAL-PEDAQSIKRSIFEITSFTDELCNLRNNGQ---PDRENLAAQTARRLKDLSGLMGDALQNAQRANPAHTAAGRLEQALRWLDNPGLDDGGLGLQALRLLTADARKLADRLNPQDRNRLLGLCSDIDRLAAQLADLERRGLGNSPEAHQIRNQLKNALRDLGDFMRRVLTDRVVDDFADITTPLKQFVEAVHADPYDPNREQNFVDKSQRLTDHSQSMTTTARLVASCGPKSKKTVEAILDTAEKVEQLTPQLVNAGRVRLHNPGSE---QHFENIHKQYADALHRLRSHVDDAIDTGEFVRASETAMRRYTNHCEGAINGADAHGLVNNSSQIARLGNRVLMTAQNEADNSEEPSFVSRVRNAADQLHNAIPPMVNNAKQIAQNPHDQYAAQNWRGTNDHLLNSVRAVGDAITGPYNPPPPSSQVIRSVNIPAPPRPPPPVELSPPPRPPPPPEYDEE----------------------EETRAFWER---------------------------------------YPLPQASHQPMLAAAHNLHNELKQWSSQENDIVAAAKRMAILMARLSQLVRGTKKDLINCSKAIADSSEEVTRLAVQLARLCTDIKMRTALLQVSERIPTIATQLKVLSTVKATMLGSAS--SEEDDEAMQQLVHNAQNLMQSVKDVVRAAEAASIKIRTNSGLRLRWLRKPMWSN
PhyML tree of selected proteins (CAE1284850_1_VCL__Sepia_pharaonis_:0.29527469,((XP_039272784_1_vinculin_like_isoform_X1__Styela_clava_:1.0280272,(((XP_018094934_1_vinculin_isoform_X1__Xenopus_laevis_:0.03496766,XP_040176600_1_vinculin_isoform_X1__Rana_temporaria_:0.04169673):0.0494462,((sp_P18206_3_VINC_HUMAN_Isoform_3_of_Vinculin_OS_Homo_sapiens_OX_9606_GN_VCL:0.12450842,(XP_020927737_1_vinculin_isoform_X1__Sus_scrofa_:0.00265937,((XP_002718451_2_PREDICTED__vinculin_isoform_X1__Oryctolagus_cuniculus_:0.00277542,(XP_038949159_1_vinculin_isoform_X1__Rattus_norvegicus_:0.00628403,NP_033528_3_vinculin__Mus_musculus_:0.00000001):0.00621056):0.00175692,(((XP_020770146_1_vinculin_isoform_X1__Odocoileus_virginianus_texanus_:0.00000001,((XP_043332426_1_vinculin_isoform_X1__Cervus_canadensis_:0.00000001,(XP_043332427_1_vinculin_isoform_X2__Cervus_canadensis_:0.00000001,KAF4018928_1_hypothetical_protein_G4228_011024__Cervus_hanglu_yarkandensis_:0.00000001):0.00000001):0.00000001,(OWK07868_1_VCL__Cervus_elaphus_hippelaphus_:0.00000001,(NP_001178299_1_vinculin__Bos_taurus_:0.00000001,(XP_027818089_1_vinculin_isoform_X1__Ovis_aries_:0.00000001,XP_005699280_1_PREDICTED__vinculin_isoform_X1__Capra_hircus_:0.00000001):0.00088681):0.00087354):0.00001248):0.00088558):0.00355883,((XP_003813044_1_vinculin_isoform_X2__Pan_paniscus_:0.00000001,(XP_009457029_1_vinculin_isoform_X1__Pan_troglodytes_:0.00000001,(sp_P18206_VINC_HUMAN_Vinculin_OS_Homo_sapiens_OX_9606_GN_VCL_PE_1_SV_4:0.00000001,XP_004049661_1_vinculin_isoform_X2__Gorilla_gorilla_gorilla_:0.00000001):0.00000001):0.00000001):0,(sp_P18206_2_VINC_HUMAN_Isoform_1_of_Vinculin_OS_Homo_sapiens_OX_9606_GN_VCL:0.00000001,XP_024109838_1_vinculin_isoform_X2__Pongo_abelii_:0.00177467):0):0.00355638):0.00000001,(XP_019668863_1_vinculin_isoform_X1__Felis_catus_:0.00177647,XP_038347906_1_vinculin_isoform_X14__Canis_lupus_familiaris_:0.0026685):0.00266426):0.00089539):0.00000001):0.01718009):0.02501481,((XP_021139948_1_vinculin__Columba_livia_:0.02473881,(XP_040558242_1_vinculin_isoform_X1__Gallus_gallus_:0.00000001,XP_019473128_1_vinculin__Meleagris_gallopavo_:0.00181605):0.00711722):0.00721689,(XP_025068505_1_vinculin_isoform_X1__Alligator_sinensis_:0.00266482,XP_006273854_1_PREDICTED__vinculin_isoform_X2__Alligator_mississippiensis_:0.00265971):0.01294786):0.0062954):0.0263095):0.03006583,(XP_005156897_1_vinculin_isoform_X1__Danio_rerio_:0.05350082,(XP_020565294_1_vinculin_isoform_X4__Oryzias_latipes_:0.02419766,(XP_015799676_1_PREDICTED__vinculin_like_isoform_X4__Nothobranchius_furzeri_:0.01890985,XP_030297248_1_vinculin_like_isoform_X4__Sparus_aurata_:0.01271787):0.00629417):0.10925783):0.03014621):0.37866934):0.13971413,(XP_031557163_1_vinculin_like__Actinia_tenebrosa_:0.89857004,(XP_030848750_1_vinculin_isoform_X6__Strongylocentrotus_purpuratus_:0.4360537,XP_038053446_1_vinculin_like_isoform_X5__Patiria_miniata_:0.69172159):0.09234615):0.07921654):0.12549232,(NP_741437_1_Vinculin__Caenorhabditis_elegans_:0.66395631,(XP_026301464_1_vinculin_isoform_X3__Apis_mellifera_:0.19287892,NP_001284813_1_vinculin__isoform_B__Drosophila_melanogaster_:0.28705276):0.14378939):0.1563468);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)