PB0229

DATABASE

Click here to access PB0229 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0229	P39060	Collagen alpha-1(XVIII) chain	COL18A1	GLCC, KNO, KNO1, KS, collagen type XVIII alpha 1 chain	Homo_sapiens	May negatively regulate the activity of homotrimeric non-collagenous domain 1 (PubMed:11257123).

Domains

Gene Ontology

PF01391 (5_Collagen) PF01392 (Fz) PF06121 (DUF959) PF06482 (Endostatin) PF20010 (Collagen_trimer)

GO:0005201 (enables) extracellular matrix structural constituent GO:0030020 (enables) extracellular matrix structural constituent conferring tensile strength GO:0046872 (enables) metal ion binding GO:0001525 (involved in) angiogenesis GO:0001886 (involved in) endothelial cell morphogenesis GO:0007155 (involved in) cell adhesion GO:0007601 (involved in) visual perception GO:0008285 (involved in) negative regulation of cell population proliferation GO:0009887 (involved in) animal organ morphogenesis GO:0030198 (involved in) extracellular matrix organization GO:0031012 (is active in) extracellular matrix GO:0005576 (located in) extracellular region GO:0005604 (located in) basement membrane GO:0005615 (located in) extracellular space GO:0005788 (located in) endoplasmic reticulum lumen GO:0062023 (located in) collagen-containing extracellular matrix GO:0070062 (located in) extracellular exosome GO:0005581 (part of) collagen trimer

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|P39060|COIA1_HUMAN Collagen alpha-1(XVIII) chain OS=Homo sapiens OX=9606 GN=COL18A1 PE=1 SV=5 MAPYPCGCHILLLLFCCLAAARANLLNLNWLWFNNEDTSHAATTIPEPQGPLPVQPTADT TTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKG IRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSPGA HTTEAGTLPAPTPSPPSLGRPWAPLTGPSVPPPSSGRASLSSLLGGAPPWGSLQDPDSQG LSPAAAAPSQQLQRPDVRLRTPLLHPLVMGSLGKHAAPSAFSSGLPGALSQVAVTTLTRD SGAWVSHVANSVGPGLANNSALLGADPEAPAGRCLPLPPSLPVCGHLGISRFWLPNHLHH ESGEQVRAGARAWGGLLQTHCHPFLAWFFCLLLVPPCGSVPPPAPPPCCQFCEALQDACW SRLGGGRLPVACASLPTQEDGYCVLIGPAAERISEEVGLLQLLGDPPPQQVTQTDDPDVG LAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKL SGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQR MPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSD GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGP PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFP GTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRG PRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGR EGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGP GLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFP GLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSV PGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKG EPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPP GPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLE AEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPPGPRGYPGIPGPKGESIRG QPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG ASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDN EVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVH LRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAF LSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVL RHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHHAY IVLCIENSFMTASK >sp|P39060-1|COIA1_HUMAN Isoform 2 of Collagen alpha-1(XVIII) chain OS=Homo sapiens OX=9606 GN=COL18A1 MAPYPCGCHILLLLFCCLAAARANLLNLNWLWFNNEDTSHAATTIPEPQGPLPVQPTADT TTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKG IRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSPGA HTTEAGTLPAPTPSPPSLGRPWAPLTGPSVPPPSSERISEEVGLLQLLGDPPPQQVTQTD DPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVL LGVKLSGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDC EEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEE GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSP CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG PQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDL EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP GPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPP GPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADG VPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDG SVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQ KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPG PPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFD FLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPPGPRGYPGIPGPKG ESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGP PGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLP RGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHH SSYVHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAG TFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFD GKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAAS CHHAYIVLCIENSFMTASK >sp|P39060-2|COIA1_HUMAN Isoform 3 of Collagen alpha-1(XVIII) chain OS=Homo sapiens OX=9606 GN=COL18A1 MAPRCPWPWPRRRRLLDVLAPLVLLLGVRAASAEPERISEEVGLLQLLGDPPPQQVTQTD DPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVL LGVKLSGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDC EEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEE GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSP CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG PQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDL EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP GPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPP GPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADG VPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDG SVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQ KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPG PPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFD FLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPPGPRGYPGIPGPKG ESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGP PGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLP RGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHH SSYVHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAG TFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFD GKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAAS CHHAYIVLCIENSFMTASK
Selected proteins from model organisms >sp|P39060|COIA1_HUMAN Collagen alpha-1(XVIII) chain OS=Homo sapiens OX=9606 GN=COL18A1 PE=1 SV=5 MAPYPCGCHILLLLFCCLAAARANLLNLNWLWFNNEDTSHAATTIPEPQGPLPVQPTADT TTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKG IRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSPGA HTTEAGTLPAPTPSPPSLGRPWAPLTGPSVPPPSSGRASLSSLLGGAPPWGSLQDPDSQG LSPAAAAPSQQLQRPDVRLRTPLLHPLVMGSLGKHAAPSAFSSGLPGALSQVAVTTLTRD SGAWVSHVANSVGPGLANNSALLGADPEAPAGRCLPLPPSLPVCGHLGISRFWLPNHLHH ESGEQVRAGARAWGGLLQTHCHPFLAWFFCLLLVPPCGSVPPPAPPPCCQFCEALQDACW SRLGGGRLPVACASLPTQEDGYCVLIGPAAERISEEVGLLQLLGDPPPQQVTQTDDPDVG LAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKL SGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQR MPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEEGDDSD GASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVEEQTTV ASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSPCLPGP PGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFP GTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRG PRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGR EGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGP GLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFP GLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDGSVLSV PGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKG EPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPP GPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLE AEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPPGPRGYPGIPGPKGESIRG QPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMG ASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDN EVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVH LRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAF LSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVL RHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAASCHHAY IVLCIENSFMTASK >sp|P39060-1|COIA1_HUMAN Isoform 2 of Collagen alpha-1(XVIII) chain OS=Homo sapiens OX=9606 GN=COL18A1 MAPYPCGCHILLLLFCCLAAARANLLNLNWLWFNNEDTSHAATTIPEPQGPLPVQPTADT TTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKG IRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSPGA HTTEAGTLPAPTPSPPSLGRPWAPLTGPSVPPPSSERISEEVGLLQLLGDPPPQQVTQTD DPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVL LGVKLSGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDC EEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEE GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSP CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG PQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDL EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP GPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPP GPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADG VPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDG SVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQ KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPG PPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFD FLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPPGPRGYPGIPGPKG ESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGP PGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLP RGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHH SSYVHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAG TFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFD GKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAAS CHHAYIVLCIENSFMTASK >sp|P39060-2|COIA1_HUMAN Isoform 3 of Collagen alpha-1(XVIII) chain OS=Homo sapiens OX=9606 GN=COL18A1 MAPRCPWPWPRRRRLLDVLAPLVLLLGVRAASAEPERISEEVGLLQLLGDPPPQQVTQTD DPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVL LGVKLSGVQDGHQDISLLYTEPGAGQTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDC EEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLDEE GDDSDGASGDSGSGLGDARELLREETGAALKPRLPAPPPVTTPPLAGGSSTEDSRSEEVE EQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGSP CLPGPPGLPCPVSPLGPAGPALQTVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTG PQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDL EALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPP GPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPP GPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADG VPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDG SVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQ KGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPG PPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFD FLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPPGPRGYPGIPGPKG ESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGP PGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLP RGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHH SSYVHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAG TFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFD GKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAAS CHHAYIVLCIENSFMTASK >NP_034059.2 collagen alpha-1(XVIII) chain isoform 2 precursor [Mus musculus] MAPRWHLLDVLTSLVLLLVARVSWAEPENVAEEVGLLQLLGDPLPEKISQIDDPHVGPAYIFGPDSNSGQ VAQYHFPKLFFRDFSLLFHVRPATEAAGVLFAITDAAQVVVSLGVKLSEVRDGQQNISLLYTEPGASQTQ TGASFRLPAFVGQWTHFALSVDGGSVALYVDCEEFQRVPFARASQGLELERGAGLFVGQAGTADPDKFQG MISELKVRKTPRVSPVHCLDEEDDDEDRASGDFGSGFEESSKSHKEDTSLLPGLPQPPPVTSPPLAGGST TEDPRTEETEEDAAVDSIGAETLPGTGSSGAWDEAIQNPGRGLIKGGMKGQKGEPGAQGPPGPAGPQGPA GPVVQSPNSQPVPGAQGPPGPQGPPGKDGTPGRDGEPGDPGEDGRPGDTGPQGFPGTPGDVGPKGEKGDP GIGPRGPPGPPGPPGPSFRQDKLTFIDMEGSGFSGDIESLRGPRGFPGPPGPPGVPGLPGEPGRFGINGS YAPGPAGLPGVPGKEGPPGFPGPPGPPGPPGKEGPPGVAGQKGSVGDVGIPGPKGSKGDLGPIGMPGKSG LAGSPGPVGPPGPPGPPGPPGPGFAAGFDDMEGSGIPLWTTARSSDGLQGPPGSPGLKGDPGVAGLPGAK GEVGADGAQGIPGPPGREGAAGSPGPKGEKGMPGEKGNPGKDGVGRPGLPGPPGPPGPVIYVSSEDKAIV STPGPEGKPGYAGFPGPAGPKGDLGSKGEQGLPGPKGEKGEPGTIFSPDGRALGHPQKGAKGEPGFRGPP GPYGRPGHKGEIGFPGRPGRPGTNGLKGEKGEPGDASLGFSMRGLPGPPGPPGPPGPPGMPIYDSNAFVE SGRPGLPGQQGVQGPSGPKGDKGEVGPPGPPGQFPIDLFHLEAEMKGDKGDRGDAGQKGERGEPGAPGGG FFSSSVPGPPGPPGYPGIPGPKGESIRGPPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTVS VPGPPGPPGPPGPPGAMGASAGQVRIWATYQTMLDKIREVPEGWLIFVAEREELYVRVRNGFRKVLLEAR TALPRGTGNEVAALQPPLVQLHEGSPYTRREYSYSTARPWRADDILANPPRLPDRQPYPGVPHHHSSYVH LPPARPTLSLAHTHQDFQPVLHLVALNTPLSGGMRGIRGADFQCFQQARAVGLSGTFRAFLSSRLQDLYS IVRRADRGSVPIVNLKDEVLSPSWDSLFSGSQGQLQPGARIFSFDGRDVLRHPAWPQKSVWHGSDPSGRR LMESYCETWRTETTGATGQASSLLSGRLLEQKAASCHNSYIVLCIENSFMTSFSK >XP_021334397.1 collagen type XVIII, alpha 1 isoform X3 [Danio rerio] MARRCLAVLERFFCLVLILSPVALQQREESGVSLLQLIGDPPPNGVSKVFDQANSPGYVFGPSSNVGQSAAAHLPNPFYR DFSLIFNIKPTSSKPGVIFSITDPTQNIMYVGVKLSAVERGKQSIIFYYTEPDSQSSYEAARFSVSSMLNIWTRFSISVL NEQVSLYFNCDSDPQVVNFERSPDDMDMDAGAGVFVGHASGADPDKFLGVIGDLRVSRDPGAAERHCEEEEDDYATEASG DYGASGDGEQPSPVQPTPPSSRPIQRPPVISRDPIQRPPVISREPIQQTVARGEKGDRGEKGAKGDRGLAGPKGDVGSGS VSGGGSKGDKGVPGEKGMKGTSGFGYPGSKGDRGPPGPPGPPGPQGPSAEVEVRGDGSVVQKVTGPRGPPGPQGPPGPPG PEGEPGDPGEDGKAGQVGPSGFPGNPGNPGPKGDKGDRGESQPGPRGPPGPPGPPGPSSGFDRPTFVDMEGSGFDMDSVR AVPGLPGPPGPPGPPGPPGSASSGSGGFGPPGPPGQNGAPGQPGLSGVPGADGKPGLPGPKGEKGDAGELGLPGPVGEKG AKGSSGPPGTTGIGGPAGLPGPIGPIGLPGPPGPPGPSFNVGFDDMEGSGVHFSSVPGVRGPVGIPGPPGVPGPQGQPGF PGLPGEKGSLGAQGNDGLPGADGFPGPQGPKGDKGERGDRGEPGRDGHGHPGQPGPPGPPGQIIYRYSEHYDEVGGTGAQ GGSGVPGQAGFPGPMGPKGDRGEPGLPGYDIKGEKGEPGLILGPDGNPLYLGGLTGQKGERGISGPVGPPGPAGPPGAKG EFGMPGRPGRPGVNGYKGEKGEPSSGSGYGYPGPPGPPGPPGPPGPAVPLDRFGRYEDYARLYPATKGEKGDQGAPGIPG SPGFSTNFDIYSLKNEMKGERGESGLKGEKGEPGGGFYDPRFGAVQGPPGNPGPAGPKGDSIRGPPGPQGPPGTPGVGYD GRPGNPGPPGPPGPPGSPSLPGPYRPPLSIPGPPGPPGPPGIPGTGSGVTVLRSHDIMIATARRQTEGTLIYILDRNDLY LRVRDGVRQVMLGDYKPLYGELDNEVAAVQPPPVVHYSQDHTANNGAEQISPPHQPIDFPTREQENRNPNPQPDPRYPDP RYPPYTDNRYTDPVEPNIRYPVQPERNPITPARRPIPPVNQPGGHAHTHTSGPGLHLIALNSPQVGNMRGIRGADFMCFQ QARAVGMKGTFRAFLSSKLQDLYSIVRRSDRETLPIVNLKDQVLFSSWESLFSDSESRMKDNAPIYSFDGRDVLRDSAWP EKMIWHGSDGRGHRQTDNYCETWRAGDRAVTGLASSLQAGQLLQQTSSSCSSSYIVLCIENSYMTQSKK >NP_445941.2 collagen alpha-1(XVIII) chain precursor [Rattus norvegicus] MAPRWHLLDMLTSLVLLLVARVSWAEPENVAEDVGLLQLLGDPLPQKISQVEDPHVGLAYVFGPYSKSSQ MAQYHFPKLFFRDFSLLFEVRPTTEAAGVLFAITDAAQVVVSLGVKLSEVRDGQQNISLLYTEPGASQTQ TGASFRLPAFVGQWTHFALSVDGSSVALYVDCEEFQRVPFARSPHGLELERGAGLFVGQAGAADPDKFQG MISELRVRKTPRVSPVHCLDEEDDDDDRASGDFGSGLEESSNLHRQETYLRPGLPQPPPVTSPPLAGGSA TEDSRTEEKEEEATVDSKGADTLPVTDSSGVWDGDVQNPGGGLIKGGLKGQKGEPGAQGPPGPAGPQGPA GPAVQSPSSQPVPGAQGPPGPQGPPGKDGIPGRDGEPGDPGEDGRPGDTGPQGFPGTPGDVGPKGEKGDP GIGPRGPPGPPGPPGPSFRQDKLTFIDMEGSGGFSGDLESLRGPRGFPGPPGPPGVPGLPGEPGRFGVNS SYAPGPAGLPGVPGKEGPPGFPGPPGPPGKEGPPGVAGQKGSVGDAGSPGPKGSKGDLGPIGMPGKSGLP GLPGPVGPPGPPGPPGPPGPGFAAGFDDMEGSGTPLWSTARSSDGLQGDPGVTGPPGAKGEVGADGVQGI PGLPGREGVAGPPGPKGEKGTQGEKGNPGKDGVGRPGLPGPPGPPGPVIYVSNEDRAVVSTPGPEGKPGY AGFPGPAGPKGDLGSKGEQGLPGPKGEKGEPGSIFSPDGTALGQAQKGAKGEPGFRGPPGPYGRPGYKGE IGFPGRPGRPGTNGLKGEKGEPGEASLGFSMRGLPGPPGPPGPPGPPGVPVYDSNAFVESGRPGLPGQQG VQGPPGPKGDKGEVGPPGPPGQFPIDLFHLEAEMKGDKGDRGDAGRKGERGEPGAPGGGFFSSSVPGPPG PPGYPGIPGPKGESIRGPPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTVSVPGPPGPPGPP GPPGAMGASAGQVRIWATYQTMLDKIREVPEGWLIFVAEREELYVRVRNGFRKVLLEARTALPHGTDNEV AALQPPLVQLHEGSSYTRREHSYPTARPWRADDILANPPRLPDRQPYPGVPHHHHHHHHHHSSHEHRPPA HPSPSPAHTHQDFHPVLHLVALNTPLSGGMRGIRGADFQCFQQARAVGLSGTFRAFLSSRLQDLYSIVRR ADRSSVPIVNLKDEVLSPSWDTLFSGSQGQLHSGARIFSFDGRDVLRHPAWPQKSVWHGSDPSGRRLMES YCETWRTEATGVTGQASSLLSGRLLEQKAESCHNSYIVLCIENSFMTSFSK >XP_025007836.2 collagen alpha-1(XVIII) chain isoform X1 [Gallus gallus] MRALQAPRWGQAPTSAPDPLCLRSQGARFPLPMALLHLGLWLLLASCCFSSSDAQLLDWIWGRPKTTGTP TAPSTAETLPTLSTPLSSAAAGDVATTQRRWEPEPSMAVPTGEESTESTDGTEQGDRSTAGITLPTGTAW TATPPRSTSPTHSPTETPLPLGTGNPNTTELPQQQEGAGGSPQRPAAARPENLSTEVSLLELIGDPPPEE ILKIYGPDNNPGYVFGPSANTGQVARYHLPSPFYRDFSLLFHIQPTTPRAGMLFAITDSTQSIIYVGVKL SDLQMGKQQIIFYYTEPGSQSSYAAATFTVPTLLNQWTRFAISVEEDEVILYLDCEEHERVRFERSPDEM ELEEGSGLFVAQAGGADPDKYQGVIADLRLRGDPRAAEHQCEEEEDDAEASGDFGSGAEDRHHPSGKDKG IPGLLDAVPVTSPPVVEGSGTRSSAGSPQQAERTRVEERLQVSTGGTGPKGEKGEKGERGPKGDSGTSGI LGTGATKGEKGEKGELGIKGSAGFGYPGSKGQKGEPGEPGPPGPLSRHTDSMSLEQVTGPPGPTGPPGKD GAPGRDGEPGDPGEDGKPGEMGPQGFPGTPGESGQKGEKGDPGVGPRGPPGPPGPPGPPGRSSKQDGLTF IDMEGSGFGGDLETLRGPRGPPGPPGPPGVPGLPGEPGRFGMNSTDLPGPPGLPGRDGTPGAPGPEGPLG PPGKDGMPGPPGPKGERGDVGDLGLPGAPGPKGSKGEAGPAGPPGETGLAGLPGPVGPRGPPGPPGPPGP PGPGYEAGFGDMEGSGLPLATGSPGPRGPSGPQGVPGLPGIKGEVGSLGQPGPPGPKGDAGVPGVDGRPG LEGFPGPQGPKGNRGSPGEKGERGQDGVGLPGPPGPPGPPGQVIYMSSEDRPLVALPGPEGRSGHAGFPG PVGPKGDPGSPGIQGAPGIKGEKGEPGVIISPDGTIVAANVKGQKGEPGLPGPMGPSGPHGRAGMKGEIG FPGRPGRPGMNGLKGEKGDPVDISSVLSLRGPPGPPGPPGPPGPPGSVVYDSNNGFSDASRPAFPGFHQF PGQKGEKGDVGAPGPPGQFPYDLSRFSASLRGDKGEAGPKGEKGEPGSSTLYGPSVTGPPGPQGYPGPPG PKGDSIVGPPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQAISIPGPPGPPGPPGPPGTSGTS LGLRTMPTYQAMLSAAHELPEGGLIFLADRQELYIRLRGGFRRVLLEEHTLVPSSALDNEVYDKLPSIHY GGAQQPVHPLRNHNPPPTARPWRGDEVVANQHHLPQPPLLQQHELLNSYYIHRWPDPAPVAAHVHQDFQP ALHLVALNTPLSGGMRGIRGADFQCFQQARQVGLAGTFRAFLSSRLQDLYSIVRRADRTAVPIVNLRDEV LFSNWEALFTGSEAPLRAGARILSFDGRDILQDSAWPQKSIWHGSDAKGRRLPESYCEAWRTDERGTSGQ ASSLSSGKLLEQSASSCQHAFVVLCIENSFMTAAKK >XP_009439942.2 collagen alpha-1(XVIII) chain isoform X1 [Pan troglodytes] MAPYPCGCHILLLLFCCLAAARADLLNLNWLWFSNEDTSHAATTIPEPQGPLPVQPTADTTTHVTPRNGS TEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARA ETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSLGAHTTEAGTLPAPTPSPPSLGRPWAPLTGPSV PPPSSGRASLSSLLGGAPPWGSLQDPDSQGLSPAAAAPSQQLQRPDVRLRTPLLHPLVTGSLGKHAAPSA FSSGLPGALSQVAVTTLIRDSGAWVSHVANSVGPGLANNSALLGADPEAPAGRCLPLPPSLPVCGRLGIS HFWLPNHLHHESGEQVRAGARAWGGLLRTHCHPFLAWFFCLLLAPPCGSVPPPAPPPCRQFCEALQDACW SRLGGGRLPVACASLPTQEDGYCVFIGPAAERVSEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDAN SGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAVVLLGVKLSGVQDGHQDISLLYTEPGAG QTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSQGLELEPGAGLFVAQAGGADPDK FQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSGLGDTRELLREETGVALKPRLPTPPPVTTPPL AGGSSTEDSRSEEIEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAG PPGSPCLPGPPGLPCPVSPLGPAGPALQPVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFP GTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGP PGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPG HKGSKGDPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSAAGPQGPP GLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSQGEKGDPGKDGVGQPGLPGP PGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGEQGSPGPKGEKGEPGSIFSPDGGA LGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPP GPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDR GDAGQKGERGEPGGGGFFSSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPG PPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTMGASSGVRLWATRQAMLGQVHEVPEGWLIFVA EQEELYVRVRNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASP PRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHTHRDFQPVLHLVALNSPLSGSMRGIRGADFQCFQQARA VGLAGTFRAFLSSRLQDLYSIVRRADRTAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVL RHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAVSCHHAYIVLCIENSFM TASK >XP_024830782.1 collagen alpha-1(XVIII) chain isoform X1 [Bos taurus] MAPDPSSGRGHHGLLLLACCLSAAQADLFSWIWSGNSAWPIAAPASKPPDSSPVWPTEDTTTHVAPRDAP TDWWKVSASPTAPLGRPEVGQGQTPTGPTASTVSLDPKEENIAGVGAKILNVAQGIRSFVQLWDNAKDTT PAESSAGAETPPPTDTMDDLSTPGPSITPQDSGTTLQLSTTALSSPDTQRTEAGTLPMPTQPPPSPGRPW FRESLVSPTPGRSSLSSVPAPAPPRGSQLPLGRPLQLDGEGLLLAAARPGQQHADDRRPMPPLPPLVTGS LGKHTALWALSSDPPAKLSHVAVSALTVDSGAWAPHVANSAGPGLANKSTLLGAAELAATEQPVPTTAGR CLPLLPSLALCGHLGIRRSWWPNHLHHTSREEVQAAVPAWGALLRTHCHRFLAWFFCLLLAPRCGPGLPP GLPPCRQFCEALEDACWSHLDGRGLPLPCASLPAREDGHCVFIGPPADEEVVEVGLQQLLGEPPPWQVAM VHDPDVGSAYEFGEDGSGGGQAARRLLPGTFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTA ARGGRQHMQLLYTEPGATHTRTAASFELPALDGRWTRLALSVDGAYARLFVDCKEVQGQPLAHSLHDLQL EPDARLFVAQAGGADPEKFQGLISELRLRRDPQVSPRQCQDEDEDDDDDGASGDLGSGLVETQEHLREEL GAPLGPRLPEAPPVTSPPLAGVGNEEDLRTEEVEESTTASSLGAQTLPSLGTVGTWDESVWSPGSSVKER GLKGQKGEPGAQGPPGPIGPQGPAGPAIDSHEAQPVSGPQGPPGPPGPPGKDGTPGRDGEPGDPGEDGKP GDTGPQGFPGTPGDVGPKGEKGDPGVGPRGPPGPQGPPGPPGPSFKPDRLTFIDMEGSGFGGDLESLRGP RGFPGPPGPPGVPGLPGEPGRFGMNSSDVPGPAGLPGVPGRDGPPGRPGPPGPPGTPGKDGQPGLTGQKG SLGEAGAPGPKGSKGDLGPVGAPGEHGLAGAPGPAGPPGPPGPPGPPGPGFAAGFDDMEGSGSPLWSTAR GAEGLQGPPGTPGVKGDPGAVGPPGSKGEVGADGAPGLPGLPGREGAAGPQGPKGEKGTQGEKGDPGKDG VGQPGLPGPPGPPGPVVYVSEQDRVLASVPGPEGRAGFAGFPGPAGPKGDLGAKGQQGIPGPKGEKGEPG TFFGPDGRALTPAQKGAKGEPGFRGPPGPYGRPGHKGEIGFPGRPGRPGMNGLKGEKGEPGDASVGFGMR GPAGPPGPPGPPGPPGTPVYDSNAFVDSGRPGPPGLPGHQGPSGLKGDKGDVGPPGPPGQFPFDLLQLGA EMKGEKGDRGAAGQKGERGEPGGGGFFGSGVPGPPGPPGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEG PQGPPGPPGPPGPPGPPSFPGPYRQTISVPGPPGPPGPPGPPGSMGTSSGGSTGLGFQQVRVWATYQMLV DQVPQVPEGWLIYVADREELYVRVRNGFRKVLLEAHVPLPHGTDNEVAVLQPPLVQLHEGNPYPRREVPH PTARSWRADDILASPPRLPHPQPYPGAPHHGAYAHLRPVPPTASPSHTHHDFQPVLHLVALNSPQSGGLR GIRGADFQCFQQARAAGLAGTFRAFLSSRLQDLYSIVRRADRATLPVVNLRDEVLFPSWEALFSGSEGQL KPGARIFSFDGRDVLQHPTWPQKSVWHGSDPSGRRLTESYCETWRTDSRAATGQASSLLAGRLLEQKAAG CHNAFIVLCIENSFMTSSSK >XP_010711461.1 collagen alpha-1(XVIII) chain isoform X1 [Meleagris gallopavo] MPRAADHAGTRGWGPWAIPRPSPATPSAATPGDADPKCSTNGEGLALLGVSGNQSPSVPKLRAVSGVDSP PAGPPEFDLLTSTLQVVGAGLAPSFPRLLPAGGHCLPLPAHLPFCSVLGTNHVRLPNYLSHSSEVEIRAA LHEWEGLLESRCHRYLEWFLCLLLVPGCSASVPVTPPPCQGFCEAVRDLCWMHSAGGRLPLPCDSLPKED EGYSCVFVNVSSENLSSEVSLLELIGDPPPEGIVKIYGHENRPGYVFGPSANTGQVARYHLPSPFYRDFS LLFHIQPTTPRAGVLFAITDSTQSIIYVGVKLSDLQMGKQQIIFYYTEPGSQSSYAAATFTVPTLLNQWA NFAISVEEDEVILYLDCEEHERVRFERSPDEMELEEGAGLFVGQAGGADPDKYQGVIADLRLRGDPRAAE YHCEEEDDTEASGDFGSGAEDRHRPLGKDKGIPGLLDAVPVTSPPVVEGSGTRSSVGSPQQAERTRVEER LQVSTGGTGPKGEKGEKGERGLKGDSGTIGILGPGTAKGEKGEKGELGIKGSAGFGYPGSKGQKGEPGEP GPPGPLSRHTDGMSLEQVTGPPGPTGPPGKDGAPGRDGEPGDPGEDGKPGEMGPPGFPGTPGESGQKGEK GDPGVGPRGPPGPPGPPGPPGPSSKQDRLTFIDMEGSGFGGDLETLRGPRGPPGPPGPPGVPGLPGEPGR FGMNSTDLPGQPGLSGRDGTPGPPGPEGPLGPPGKDGMPGLPGPKGERGDVGDLGLPGAPGPKGSKGEAG PAGPPGETGLAGLPGPVGPRGQPGPPGPPGPPGPGYEAGFGDMEGSGLPLATGSPGPRGPSGPQGVPGLP GIKGEVGSLGQPGLPGPKGDAGVPGVDGRPGLEGFPGPQGPKGNRGSPGEKGERGQDGVGLPGPPGPPGP PGQVIYISSEDRPLAALPGPEGRPGLAGFPGPVGPKGDPGSPGIQGAPGMKGEKGEPGVIISPDGTIVAA NMKGQKGEPGLQGPMGPSGPHGRAGMKGEIGFPGRPGRPGMNGLKGEKGDPVDISGMLSLRGPPGPPGPP GPPGPPSSVVYDSNNGFSDASRPAFPGFHQFTGQKGEKGDVGAPGPPGQFLYDLSRFSANLRGDKGEAGP KGEKGEPGGSTLYGPGVTGPPGPQGYPGPPGPKGDSIVGPPGPPGPQGPPGIGYEGRQGPPGPPGPPGPP SFPGPHRQAISIPGPPGPPGPPGPPGTSGTSLGLRAMPTYQAMLSAAHELPEGGLIFVTDRQELYVRLRG GFRRVLLEEHTLIPSSALDNEVYDKLPSIHYGGAQQPVHPLRNHSPPPTARPWRGDEVVANQHRLPQPPL LQQHELLNSYYIHRWPDPASVAAHVHRDFQPALHLVALNTPLSGGMRGIRGADFQCFQQARQVGLAGTFR AFLSSRLQDLYSIVRRADRTSVPIVNLRDEVLFSNWEALFTGSEAPLRAGARILSFDGRDILQDSAWPRK SIWHGSDVKGRRLPESYCEAWRTDERGTSGQASSLSSGKLLEQSASSCQHAFVVLCIENSFMTAAKK >XP_020927188.1 collagen alpha-1(XVIII) chain isoform X1 [Sus scrofa] MAPDPSGRPGHLGLLLLLACCLAATWADPFPWLWFSEATMPKATPASVPQATPAPVPPGSSPEQRPETPP RTWTPGMAPPTRGKPRPALSLVWRGWRGARARAPLSPRPPREPGPQGGEHRGCGSQDPERGSGHPALHPA VGRHHAPRELRRRGDASPPTPTDPLTTPGPSSTLWESGTTLWLSSGAPSSPDTQRTEAGTQPLPTQPPPS PGGPLAPFRAPSVPPPAPGRASLSPAPGGAPPWGSQLSPGWSQELDGKGLLPVAARPGQQHRHPDVRRPP LLPLVTGSPGAHGPSALSSGAPATLSYVALAALIGDGGAWLPHVANSSGPGLAHTSAQLGATGRCLPLPP SLAICSRLGIGRVWLPNHLHHGSGEEVQAAARAWGALLQTRCHRFLAWFFCLLLAPPCGLGPAAPPPCRQ FCETLEDACWSHLDGGGLPVPCASLPAREDGHCVFIGPAAEGEAVEVGLQQMLGEPLPRQVALVHDPDVG PAYEFDGISGVGQAALSLVPRTFFHDFSLLMRVRPASAGAGVLFAVTDAAQAVVLVGVKLAAARGGQQQV QLLYTEPGATRTRTAASFTLPALHGRWTHLALSVDGAHVALFVDCEEVQLEPLSRSLRALQLEPDARLFV AQAGRADPDKFQGMISELRVRGDPQVSPLQCRYGDEDEDDSDNEASGDLGSGLAEEAGERLGAPSGAPLR PRLPEAPPVTSPPLAGAGDEEDSRTEEVEEATTVPSPGAQTLPGSGAVTTWDGSSWSPGDSLEERGLKGQ EEPGAQGLPGQASPQGPTGPVMRSPEAQPVPGPQGPPGPPGPPGKDGAPGRDGEPGDPGEDGKPGDTGPQ GFPGTPGDVGPKGEKGDPGVGPRGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLESLRGPRGFPGP PGPPGVPGLPGEPGRFGMNSSDVPGPAGLPGVPGRDGAPGPPGPPGPPGFPGRDGQAGQTGQKGSVGEVG APGPKGSKGDPGPVGAPGNPGLAGVPGPAGPPGPPGPPGPPGPGLAAGFDDMEGSGGPFWWAAQGADRPQ APPGPPGVKGDPGAVGPAGTKGEVGADGAPGLPGLPGREGAAGPQGPKGEKGTRGDKGDPGKDGVGQPGL PGPPGPPGPVVYVSDRAVASVPGPEGRTGFAGFPGPAGPKGDLGSKGQPGLPGPKGEKGEPGTVFSPDGR PLTPAQKGAKGEPGFRGPPGPYGRPGHKGEIGFPGRPGRPGMNGLKGEKGEPGDASVGFSLRGPPGPPGP PGPPGPAGTPVYDSNAFVESGRPGPPGLPGYQGPPGPKGDKGEMGPPGPPGQFPFDLLHMEAELKGEKGD RGEAGQKGERGEPGGGGFFGSSVPGPPGPPGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPP GPPGPPGPPSFPGPYRQTISVPGPPGPPGPPGPPGSMGGSSGQVRVWATYQTMLDKVPEVPEGWLMFVAE REELYVRVRNGFRKVLLEARTPLPRGTGTDNEVAALQPPVVQLHEGNPYPRREPPQPTARAWRGDDIRAS PPRLPVAQPYPGAPHHGAYVHPRPVHPTGSPAHTHHDFQPVLHLVALNSPQSGGLRGIRGADFQCFQQAR AVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLRDEVLFPSWEALFSGSEGQLKPGARIFSFDGRDV LQHPAWPQKSVWHGSDPSGRRLTESYCETWRTEARTATGQASSLLAGRLLEQKAAGCHHAFIVLCIENSF MTSASK >XP_038299617.1 collagen alpha-1(XVIII) chain isoform X1 [Canis lupus familiaris] MARHPGRCLLLLLLLTCCPAAAQVDLLSLNWLWSTRTAGPTAEPVSEAPGSPHVQPRDETGTPVTPQPGP TEQGNAPASPEPPLRGLETDEHAASAAPSAPPAGPDPKEEKEENIAGVGAKILNVAQGIRSFVQLWDDTT RPESSSTAGTPAPVTPTSPLALPGPSRPPPENGTALWLGSTDAPRVEASTLPAPTRLPPSLDRPRAALRE PSGPPPSPESRGSEVGLLQLLGEPPPQQVTQVDDPDVGPAFVFGPDANSGQVARYHVPSPFFRDFSLLMH VRPATEGPGVLFAITDAAQAVVSVGVKLSGVRDGQQHVQLLYTEPGAARTRTAASFRLPAFTGQWTRLAL SVDGATVALFVDCELFQRVPLERSPGGLQLEPGAGLFVAQAGGADPDKFQGMIAELRVRGDPHVSPLHCL EEDDDDSGGVSGDFGSGLEDDREPSGLLPKAELPEAPPVTSPPLTGGRDVEDSRMEEIEEEATASPLGAR TLPGSATVTAESAQRLGGSLQEAPTGPAAHNPEAWPGPGPQGPPGPPGPPGKDGTPGRDGEPGDPGEDGR PGDPGPQGFPGTPGDVGPKGEKGDPGVGPRGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLESLRG PRGFPGPPGPPGVPGLPGEPGRFGMNSSDVPGPAGLPGVPGRDGPPGLPGAPGPPGPPGKEGGPGKPGPK GSPGDAGAPGPKGSKGDPGPIGVPGESGLAGPPGPAGPPGPPGPPGPPGPGLAAGFVDMEGSGEPFWSTA HGASGPQGPPGLPGVKGDPGIVGPPGAKGEVGADGPPGFPGLPGREGTAGAQGPKGEKGTQGEKGEPGRD GVGQPGLPGPPGPPGPVVYVSEQERAATGVPGPEGRPGHAGFPGPAGPKGDLGSKGQRGPPGPKGEKGEP GPAFSPDGSMLAPAQKGAKGEPGFRGPPGPYGRPGHKGEIGFPGRPGRPGMNGLKGEKGEPGQASAGFGM TGPPGPPGPPGPPGPPGTPVYDSNAFMEPGHPGPPGLPGHQGPSGPKGDKGDVGPPGPPGQFPFDLLQLG AEMKGEKGDRGDAGQKGERGEPGGGGFFGSSVPGPPGPPGYPGIPGPKGESVQGHPGPPGPQGPPGIGHE GRRGPPGPPGPPGPPGPPSFPGPYRQTISVPGPPGPPGPPGPPGTMGTSSGQVRIWATYQTMLDKVPDVP EGWLMFVAEREELYVRVRNGFRKVLLEARVPLPRGTDNEVAALQPPVVQLHEGNPYPRREPTHATARPWR ADDILASPPRLLDPQPYPGAPHHGSYVHFQPARPTGGPVHTHTHTHQDFQPVLHLVALNSPQPGGMRGIR GADFQCFQQARAAGLAGTFRAFLSSRLQDLYSIVRRADRTGVPVVNLRDEVLFPSWEALFSGSEGQLKPG ARIFSFDGRDVLQHPAWPRKSVWHGSDPSGRRLTDSYCETWRTEAPAATGQASSLLAGRLLEQEAASCRH AFVVLCIENSVMTSFSK >XP_034803833.1 collagen alpha-1(XVIII) chain isoform X1 [Pan paniscus] MAPYPCGCHILLLLFCCLAAARADLLNLNWLWFSNEDTSHTATTIPEPQGPLPVQPTADTTTHVTPRNGS TEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARA ETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSLGAHTTEAGTLPAPTPSPPSLGRPWAPLTGPSV PPPSSGRASLSSLLGGAPPWGSLQDPDSQGLSPAAAAPSQQLQRPDVRLRTPLLHPLVTGSLGKHAAPSA FSSGLPGALSQVAVTTLIRDSGAWVSHVANSVGPGLANNSALLGADPEAPAGRCLPLPPSLPVCGRLGIS HFWLPNHLHHESGEQVRAGARAWGGLLRTHCHPFLAWFFCLLLAPPCGSVPPPAPPPCRQFCEALQDACW SRLGGGQLPVACASLPTQEDGYCVFIGPAAERVSEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDAN SGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAVVLLGVKLSGVQDGHQDISLLYTEPGAG QTHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDK FQGVIAELKVRRDPQVSPMHCLDEEGDDSDGASGDSGSGLGDARELLREETGAALKPRLPTPPPVTTPPL AGGSSTEDSRSEEIEEQTTVASLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGQAG PPGSPCLPGPPGLPCPVSPLGPAGPALQPVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFP GTPGDVGPKGDKGDPGIGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGP PGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPG HKGSKGDPGPAGARGESGLAGAPGPAGPPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSAAGPQGPP GLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSQGEKGDPGKDGVGQPGLPGP PGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGSA LGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPP GPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDR GDAGQKGERGEPGGGGFFSSSLPGPPGPPGPRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPG PPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGTTGTMGASSGVRLWATRQAMLGQVHEVPEGWLI FVAEQEELYVRVRNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDIL ASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHTHRDFQPVLHLVALNSPLSGSMRGIRGADFQCFQQ ARAVGLAGTFRAFLSSRLQDLYSIVRRADRTAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGK DVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQSAVSCHHAYIVLCIEN SFMTASK >XP_023094382.1 collagen alpha-1(XVIII) chain isoform X1 [Felis catus] MARDPGGRLGLLLLLLLLTYGLAAAQVDLLNWLWAPRTAGPTVEPASAPPRSPHVQPTEETAAHVAPRDD PTEQGRAPASPEPPPGRLETGRDQASAVPTASTAGPDTKEENIAGVGAKILNVAQGIRSFVQLWDGTTPS QSSTGAETPAPGTPTAPLTLPGPSGAPPEDGTTLWLSSRALTSPDTQRTEAGTLPVPTQLPPSPGRPRAP LREPSVPPSSPGRASLSSAPGGAPPRGTQPSPRRPHDLDGGGPSPVAARARRQRRLADSRRPAPHLLPLV TGLPGAHAAPLALSSDLPALVSPIPLPAVTGDKGAWAPHVANSVGPGLANNSALPGADLPTPTRQPARPA GRCLPLPPSLPVCGHLGIGRSWLPNHLRHASSEEVRAAARAWGALLRTHCHRFLAWFFCLLLAPPCGAGP LPAPPPCRQFCEALEDACWSHLDGGGLPVTCASLPAQEDGVCVFIGPGAESLGTEVGLLQLLGEPPPQQV AQVDDPDVGPAFVFGPDANSGQVARYHFPSPFFRDFSLLFHVRPATEGAGVLFAITDAAQAVVSVGVKLS AVRDGQQHIQLLYTEPGATRTRTAASFRLPAFTGQWTRFALSVDGATVALFVDCELFQRVPLVRSPRALE LEPGAGLFVAQAGGADPSKFQGRIAELRVRGDPRVSPLHCLEEDDEDSGGVSGDFGSGLEENRELLREQS GLSPKPSLPEAPPVTSPPLAGGRNVEDARTEEIEEETTMSSLGAWTLPGSDTVTAWSVRSPGGGPEEGPA GSAVHSPDAQPVPGPQGPPGPPGPPGKDGAPGKDGEPGDPGEDGKPGDPGPQGFPGTPGDMGPKGEKGDP GVGPRGPPGPQGPPGPPGPSFRHDRLTFIDMEGSGFGGDLESLRGPRGFPGPPGPPGVPGLPGEPGRFGM NSSDVPGPAGLPGVPGRDGAPGLPGAPGPPGPPGRDGGPGKTGQKGSPGEAGAPGPKGSKGDPGPTGAPG ETGLAGAPGPAGPPGPPGPPGPPGPGLAAGFEDMDGSGGPFWATAHGASGPQGPPGLPGVKGDPGIAGPP GAKGEVGADGPPGFPGLPGREGTAGAQGPKGEKGTQGEKGDPGRDGVGQPGLPGPPGPPGPVVYVSEQDR AVAGVPGPEGRPGYAGFPGPAGPKGDLGSKGQRGPPGPKGEKGEPGPVFSPDGGTLGPAQKGAKGEPGFR GPPGPYGRPGHKGEIGFPGRPGRPGMNGLKGEKGEPGHASVGFGVRGPPGPPGPPGPPGPPGTPVYDSNA FMESGRPGPPGLPGYQGPPGPKGDKGEVGPPGPPGQFPLDLLQLEAEMKGEKGDRGDPGQKGERGEPGGG GFFGSSVPGPPGPPGYPGIPGPKGESIRGQPGPPGPQGPPGIGHEGRQGPPGPPGPPGPPGPPSFPGPYR QTISVPGPPGPPGPPGPPGTMGTSSGQVRIWATYQTMLDKVPEVPEGWLIFVAETEELYVRVRNGFRKVL LEARTPLPRGTDNEVAALQPPLVQLHEGHPYPRRELTHSTARPWRADDILAGPPRLPDPRPYPGAPQNGP YLHVQPARPTGGPARTHAHQDFQPVLHLVALNSPQPGGMRGIRGADFQCFQQARAVGLAGTFRAFLSSRL QDLYSIVRRADRTGVPIVNLRDEVLFPSWEALFSGSSEGQLKPGARVFSFDGRDVLQHPAWPQKSVWHGS DPSGRRLTDSYCETWRTEDAAAAGQASSLLAGRLLAQKAASCRNAFIVLCIENSFMTSSSK >XP_027816975.1 collagen alpha-1(XVIII) chain isoform X3 [Ovis aries] MAPDPSSRCGHHSLLLLACCLSAAQAQLLSWLWSGNSAWPTAAPASKTPDSSPVWPTEETTTHVAPRDAS TDWWKVPASPTDPLGRPEAGQGQTPAGPTASSSSPDLKEENIAGVGAKILNVAQGIRSFVQLWDDAQDTT PAESSARAGMLAPATPTDPLSTAPAEGSTRAETPPPVDTTDTLSTPGPSSTPQDSGTTLQPSTKALSSPD TQMTEAGALPVPTQPPPSPGRPWFRESLVPPTPDGEVVEVGLQQLLGEPPPWQVAVVHDPAVGPAYEFGE DGSGGGQAARSLLPSAFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTAARGGRQHLQLLYTE PGATDTRTAASFELPALDGRWTRLALSVDGAYARLFVDCEEVQGQPLAHSLHDLQLEPDARLFVAQAGGA DPEKFQGLISELRLRRDPRVSPRQCQDEDEDDDDDGASGDLGSGLMETQEHPREELGTPLGPRLPEAPPV TSPPLAGVGTEEDLRTEEVEESTTVSSLGAQTLPSLGTVGTWDESVWSPGSSVKEQGLKGQKGEPGAQGP PGPIGPQGPAGPAIDSHEAQPVSGPQGPPGPPGPPGKDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGD VGPKGEKGDPGVGPRGPPGPQGPPGPPGPSFKPDRLTFIDMEGSGFGGDLESLRGPRGFPGPPGPPGVPG LPGEPGRFGMNSSDVPGPAGLPGVPGRDGLPGVPGPPGPPGIPGKDGQPGLTGQKGSLGEAGAPGPKGSK GDPGPIGAPGEHGLAGAPGPAGPPGPPGPPGPPGPGFAAGFDDMEGSGSPFWSTARGADGLQGPPGTPGV KGDPGAVGPPGSKGEVGADGAPGFPGLPGREGAAGPQGPKGEKGTQGEKGDPGKDGVGQPGLPGPPGPPG PVVYVSEQDRVLASVPGPEGRAGFAGFPGPAGPKGDLGAKGQQGIPGPKGEKGEPGTFFGPDGRALTPAQ KGAKGEPGFRGPPGPYGRPGHKGEIGFPGRPGRPGMNGLKGEKGEPGDASVGFGMRGPPGPPGPPGPPGP PGTPVYDSNAFVDSGRPGPPGLPGHQGPSGPKGDKGDVGPPGPRGQFPFDLLQLGAEMKGQKGERGAAGQ KGERGEPGGGGFFGSGVPGPPGPPGYPGIPGPKGESVRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPP GPPSFPGPYRQTISVPGPPGPPGPPGPPGSMGTSSGVRVWATYQMLVDQVPQVPEGWLIYVADREELYVR VRNGFRKVLLEAHMPLPHGTDNEVAVLQPPLVQLHEGNPYPRREAPHPTARSWRADDILASPPRLPHPQP YPGAPHHGTYAHLRPVTSTASPSHTHHDFQPVLHLVALNSPQSGGLRGIRGADFQCFQQARAAGLAGTFR AFLSSRLQDLYSIVRRADRGSLPVVNLRDEVLFPSWEALFLGSQGWLKPSARIFSFDGRDVLQHPAWPQK SVWHGSDTSGRRLTESYCETWRTDSRAATGQASSLLSGRLLEQKAAGCHNAFIVLCIENSFMTSSSK >XP_030860999.1 collagen alpha-1(XVIII) chain [Gorilla gorilla gorilla] MAPYPCGCHILLLLFCCLAAARANLLNLNWLWFNNEDTSHAATTIPEPQGPLPVQPTADTTPADTHVTPQ NGSTEPATAPGSPEPPSELLEDSQDTPTSAESLDAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESL ARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSLGAHTTKAGTLPAPTPSPPSLGRPWAPLTG PSVPPPSSGRASLSSLLGGAPPWGSLQDPDSQGLSPAAAAPSQQLQRPDVRLRAPLLHPLVTGSLGKHAA PSAFSSGLPGALSQVAVTTLIRDSSAWVSHVANSVRPGLANNSALLGADPEAPAGRCLPLPPSLPVCGRL GISRFWLPNHLHHESGEQVRAGARAWGGLLRTHCHPFLAWFFCLLLAPPCGSVPPPAPPPCRQFCEALQD ACWSRLGGGRLPVACASLPTQEDGYCVFIGPAAVGRAGPGVGLRQAPCGKVSGNDQCPAVPTPCAPPQGR PGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVYDSNVFAESSRPGPPGLPGNQGPPGPKG AKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGPRGYPGIP GPKGESIRGQPGPHGPQGPPGIGYEGRQGPPGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPGPPGPPGT MGASSGVRLWATRQAMLGQVHEVPEGWLLFVAEQEELYVRVRNGFRKVQLEARTPLPRGTDNEVAALQPP MVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHTHRDFQ PVLHLVALNSPLSGSMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRAALPIVNLKDE LLFPSWEALFSGSEGPLKPGARIFSFDGKDILRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATG QASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK >XP_013226958.1 LOW QUALITY PROTEIN: collagen alpha-1(XVIII) chain [Columba livia] MALAPCCLGFLLLLACCFSSSETQLLDWIWSSRKTTGSTAAPSKGTTAPELLASVAAPTPNTSTGTRGDQ VEGDITTPQHWEQDPGTVAPMGEGTVAENTEQWDGNATGLVESTAQPSIAPPRSTSPAPGQDAATSSTED LQLLGTGTTKDLQLLGTGTAEDPQLLGTGTTDDLQLLGMGTTKDPQFLGTGTTEDPQLRGTGTTKNPQFL GTGTTEDLQLLGTGTSKDQKLLGTVTPAVMGIPVSLQRPVGPWPGSAPFPFSPGDDPHEQVVLPQNPTAQ PPQTHHGASPAPPNLQRGTGRWGLVLAGMNGSRSPPLPNRRLTNSVDPPLADNSRPLGFDLLTSAARLYS SSGVGLAAFLPRLISPTGHCLPIPTHLPFCSVLGTHHVRLPNYLRHGSEVEIRAALHDWEGLLESRCHLY VEWFLCLLLLPGCSASVPVTPPPCQGFCEAVRDQCWMHLAGGRLPLPCDALPEEDEGYSCVFINASAENL SAEVSLLELIGDPPPEEILKIYGPDNNPGYVFGPNANTGQVARYHLPSPFYRDFSLLFHIQPTSPRAGVL FAITDSSQSIIYMGVKLSELQAGKQQIIFYYTEPGSPSSNAAATFTVPTLLNQWTRFAISVEEDEVILYL DCEEHERTHFERSPDEMELEDGSGLFVAQAGGADPDKYQGVIADLKLRGDPRAAERQCEEEEDDTEEVSG DFGSGAEGGHQPSGKDRGVPGLVDAVPVTSPPVAAGGGVRSGGGSLQQAERTRAEETLRVSAGGTGPKGE KGEKGERGLKGDSGTGSIVGTGSIKGEKGEKGEVGIKGSAGFGYPGSKGQKGEPGDPGSPRTLSRHADGS VVEQITGPPGPPGKDGAPGRDGEPGDPGEDGKPGAMGPQGFPGMPGEPGLKGEKGDPGVGPRGPPGPPGP PGPPGPSSKHDKLTFIDMEGSGFGGDLESLQGPRGPPGPPGPPGVPGLPGEPGRFGMNQTDLPGPPGLPG RDGTPGSPGPAGPQGPSGRDGAPGQPGPKGERGDVGDLGLPGAPGPKGSKGETGPAGAPGETGLAGLPGP MGPRGPPGPPGPPGPPGPGYEAGFSDMEGSGLPFAASSPGQPGPEGPQGVPGLPGMKGEVGSPGQPGLPG PKGDAGVPGVDGRPGLEGFPGPQGPKGDRGSPGEKGERGQDGVGLPGPPGPPGPPGQVITVSSEDRSLVA LPGPEGRPGHAGFPGPLGPKGDQGPSGPQGPPGLKGEKGEPGVIISPDGTVVTAKVKGEKGEPGLRGPVG PSGPPGRAGMKGEIGFPGRPGRPGMNGLKGEKGDPADVSSVLGLRGPPGPPGPPGPPGPPGSVVYDSSNA FSDSGRPVLPAFPGFHQFPGQKGEKGDTGAPGPPGHFPYDLSHFGASLRGDKGDAGPKGEKGEPGSTPLY GPSVSGLPGPPGPQGYPGLPGPKGDSIVGPPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQAI SIPGPPGPPGPPGPPGTSGMSLGVTRPLPTYQAMLSAAHELPEGSLVFLTDRQELYVRLRGGFRRVLLEE HTLIPSSALVSSLSSIHPSIQPSISNHSRPQPSISNHSPPPTARPWRGDEVVANQHRLPEQPLLHHQHEL LNSYYIHRRPDPAPVAAYVHQDFQPALHLVALNTPLSGSMRGIRGADFQCFQQARQVGLAGTFRAFLSSR LQDLYSIVRRADRAAVPIVNLRDEVLFSNWEALFTGSGAPLRAGARILSFDGRDVLRDAGWPQKSVWHGS DAKGRRLPESYCEXQIPATGQASSLGSGKLLEQVASSCQHNFIVLCIENSFMTAAKK >XP_017907685.1 PREDICTED: collagen alpha-1(XVIII) chain isoform X1 [Capra hircus] MAPDPSSRRGHHSLLLLACCLSAAQAQLLSWLWSGNSAWPTAPPASKTSDSSPVWPTEETTTHVAPRDAS TDWWKVPASPTDPLGRPEAGQGQTPAGPTASSSSPDLKEENIAGVGAKILNVAQGIRSFVQLWDDAQDTT PAESSARAGMLAPATPTDPLSTALAEGSTRAETPPPTDTTDTLSTPGPSSTPQDSGTTLQSSTKALSSPD TQMTKAGALPVPTQPPPSPGRPWFRESLVTPTPDGEVVEVGLQQLLGEPPPWQVAVVHDPAVGPAYEFGE DGSGGGQAARSLLPSTFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTAARGGRQHLQLLYTE PGATDTRSAASFQLPALDGRWTRLALSVDGAYARLFVDCKEVQGQPLAHSLHDLQLEPDARLFVAQAGGA DPEKFQGLISELRLRRDPRVSPRQCQDEDEDDDDDGASGDLGSGLMETQEHPREELGTPLGPRLPEAPPV TSPPLAGVGTEEDLRTEEVEESTTASSLGAQTLPSLGTVGTWDESVWSPGSSVKEQGLKGQKGEPGAQGP PGPIGPQGPAGPAIDSHEAQPVSGPQGPPGPPGPPGKDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGD VGPKGEKGDPGVGPRGPPGPQGPPGPPGPSFKPDRLTFIDMEGSGFGGDLESLRGPRGFPGPPGPPGVPG LPGEPGRFGMNSSDVPGPAGLPGVPGRDGLPGLPGPPGPPGIPGKDGQPGLTGQKGSLGEAGAPGPKGSK GDPGPIGAPGEHGLAGAPGPAGPPGPPGPPGPPGPGFAAGFDDMEGSGSPFWSTARGADGLQGPPGTPGV KGDPGAVGPPGSKGEVGADGAPGFPGLPGREGAAGPQGPKGEKGTQGEKGDPGKDGVGQPGLPGPPGPPG PVVYVSEQDRVLASVPGPEGRAGFAGFPGPAGPKGDLGAKGQQGIPGPKGEKGEPGTFFSPDGRALTPVQ KGAKGEPGFRGPPGPYGRPGHKGEIGFPGRPGRPGMNGLKGEKGEPGDASVGFGMRGPPGPPGPPGPPGP PGTPVYDSNAFVDSGRPGPPGLPGHQGPSGPKGDKGDVGPPGPRGQFPFDLLQLGAEMKGQKGERGAAGQ KGERGEPGGGGFFGSGVPGPPGPPGYPGIPGPKGESVRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPP GPPSFPGPYRQTISVPGPPGPPGPPGPPGSMGTSSGGSTGLGFQQVRVWATYQMLVDQVPQVPEGWLIYV ADREELYVRVRNGFRKVLLEAHTPLPHGTDNEVAVLQPPVVQLHEGNPYPRREAPHPTARSWRADDILAS PPRLPHPQPYPGAPHHGAYAHFRPVTSTASPSHTHHDFQPVLHLVALNSPQSGGLRGIRGADFQCFQQAR AAGLAGTFRAFLSSRLQDLYSIVRRADRGSLPVVNLRDEVLFPSWEALFLGSEGWLKPGARIFSFDGRDV LQHPAWPQKSVWHGSDTSGRRLTESYCETWRTDSRAATGQASSLLSGRLLEQKAAGCHNAFIVLCIENSF MTSSSK >XP_006022141.1 collagen alpha-1(XVIII) chain isoform X2 [Alligator sinensis] MAPAKPSLCLLLLLTCCFSLSEAQLLSWLGWERPKQEARTVPPEENSTTEEQTMGSLTSPAASTLHAPLQ TTAQQEGKIRNIFTLKRQEPESDVTVPTAAPSQTPKDKEENIAGVGAEILTVAEGIRSLVQLWDEKVTKG TEGTEELTTAAPFTAAHPSLSATSLVTGPAGIENMTADSTGGAQSPLETGQPEVVFPVPTGPPPVLWNRT RVLLQQPASPPPENFSTEVGLLQLIGDPPPEQITKIYGPDNNPGYVFGPDANTGQVARYHLPSPFYRDFS LLFHIQPTTNKAGVLFAITDSSQAVIYIGVKLSDAKEGKQHIIFYYTEPGSQSSYAAATFTVSSLLNQWT RFAVSVEDEEVVLFLDCEEYDRIRFERSPDEMELEDGSGLFVGQAGGADPDKYQGVIADLKIKNDPHAAV LQCEEDEDDTEEMSGDFGSGVEEKLHSSGKERGIPTVSGLPKPPPVTSPPIAGRPVEKVSGSSQLQTEHI KAEETPPVSTGARVGQKGEKGEKGERGPKGDSRTGGVPSTGGVKGEKGEKGELGVKGSAGFGYPGSKGQK GEPGAPGDPGPPGPPGPSGTILQHQDGSVVEHVTGPPGAMGPPGLPGKDGFPGKDGEPGDPGEDGKPGDT GPQGFPGTPGEPGLKGEKGDPGVSVKGSPGPPGPPGPPGIPGLSSKQDKLTFIDMEGSGFAGDLESLRGP RGPPGPPGPPGVPGLPGEPGRFGMNHTAIPGPPGLPGKDGSPGLQGPPGPPGPPGREGLPGQPGFRGEKG DSGDLGLPGAPGPKGSKGETGPQGSPGETGLAGLPGPIGPRGQPGPPGPPGPGYEAGFGDMEGSGIPIVS SVPGPRGPEGPQGPPGLPGLKGDIGSSGQPGVPGQKGDPGTPGTNGQPGLEGFPGPQGPKGDQGSPGVKG ERGQDGVGLPGPPGPPGPPGEIVYASNKTLAVLPGPEGRPGHAGFPGPVGPKGEAGSPGLQGFPGMKGEK GEPGVIIGPDGTVTALDTKGEKGEPGLRGPVGPLGPHGRPGQKGEIGFPGRPGRPGMNGLKGEKGDPADP SGGFSLPGLPGPPGPPGPPGSPGSIVPVYDGNAFTESGPPGPPGLPGYQGVPGHKGEKGDTGAPGPPGQF PYDLSRFGAAFRGEKGEQGDSGLKGEKGEPGGGTLYGPGVVGQPGLPGPQGYPGLPGPKGDSIVGPPGPP GPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQTNVVGPPGPPGPPGPPGTSGTSASSGLKILPSYQAM LSTAHEVPEGWLVFIVDREELYVRVRNGFRRILLEDHTVISSTALDNEVYDKPPSIHFAHGSSPSSGSQP HVPVHPHRDYNTYATVRPWGGDDIIANHHRLPKQPSIHQGAQHQQENLHDFYPNRRPEDTPSAMHTHHDF QPALHLVALNTPLSGSMRGIRGADFQCFQQAREVGLTGTFRAFLSSRLQDLYSIVRRADRSSVPIVNLRD EVLFNNWESLFSGTEAQLRAGAHILSFNGKDILRDSTWPQKSVWHGSDSRGRRLTENYCETWRTDSSVVT GQASSLSSGKLLEQKASSCQNAFVVLCIENSFMTSSKK >XP_019347546.1 PREDICTED: collagen alpha-1(XVIII) chain isoform X1 [Alligator mississippiensis] MHDEIPAEVAGSLDNQLSHYVRNSNHSVSHGNTTPHILKNADSSQSMQSIEPSDKQFGKAVADLNRSHSD SVSNATNFVDFFPANNSDSLGFDLLTYTMQLYSNNSTGLASFFPGLTPTAGHCLPLPANLPYCNNLGLKH FRMPNYFNHGSDMEIRASLHEWEGLLKSRCHRYLEWFYCLLLVPGCNASIPITPPPCQGFCEALKDLCWM HLKEGHLPISCDSLPAEDNEYSCVFINVSAGNNDRGNICYQLFLFLPPENFSTEVGLLQLIGDPPPEQIT KIYGPDNNPGYVFGPDANTGQVARYHLPSPFYRDFSLLFHIQPTTNKAGVLFAITDSSQAVIYIGVKLSD AKEGKQHIIFYYTEPGSQSSYAAATFTVSSLLNQWTRFAVSVEDEEVVLFLDCEEYDRIRFERSPDEMEL EDGSGLFVGQAGGADPDKYQGVIADLKIKNDPHAAVLQCEEDEDDTEEMSGDFGSGVEEKLHSSGKERGI PTVSGLPKPPPVTSPPIAGRPVEKVSGSSQLQTEHIKAEETPPVSTGARVGQKGEKGEKGERGPKGDSRT GGVPSTGGVKGEKGEKGELGVKGSAGFGYPGSKGQKGEPGAPGDPGPPGPPGPSGTILQHQDGSVVEHVT GPPGAMGPPGLPGKDGLPGKDGEPGDPGEDGKPGDTGPQGFPGTPGEPGLKGEKGDPGVSVKGSPGPPGP PGPPGIPGLSSKQDKLTFIDMEGSGFAGDLESLRGPRGPPGPPGPPGVPGLPGEPGRFGMNHTAIPGPPG LPGKDGSPGLQGPSGPPGPPGREGLPGQPGFRGEKGDSGDLGLPGAPGPKGSKGETGPQGSPGETGLAGL PGPIGPRGQPGPPGPPGPGYEAGFGDMEGSGIPIVSSVPGPRGPEGPQGPPGLPGLKGDIGSLGQPGVPG QKGDPGTPGTNGQPGLEGFPGPQGPKGDQGSPGVKGERGQDGVGLPGPPGPPGPPGEIVYASNKTLAVLP GPEGRPGHAGFPGPVGPKGEAGSPGLQGFPGLKGEKGEPGVIIGPDGTVTALDTKGEKGEPGLRGPVGPL GPHGRPGQKGEIGFPGRPGRPGMNGLKGEKGDPADPSGGFSVPGLPGPPGPPGPPGSPGSIVPIYDGNAF TESGPPGPPGLPGYQGVPGHKGEKGDTGAPGPPGQFPYDLSRFGAAFRGEKGEQGDSGLKGEKGEPGGGT LYGPGVGQPGLPGPQGYPGLPGPKGDSIVGPPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPSFPGPHRQT NVVGPPGPPGPPGPPGTSGTSASSGLKILPSYQAMLSTAHEVPEGWLVFIVDREELYVRVRNGFRRILLE DHTVISSTALDNEVYDKPPSIHFARGSSPSSGSQPHVPVHPHRDYNTYATVRPWGGDDIIANHHRLPKQP SIHQGAQHQQENLHDFYPNRRPEDTPSAMHTHHDFQPALHLVALNTPLSGSMRGIRGADFQCFQQAREVG LTGTFRAFLSSRLQDLYSIVRRADRSSVPIVNLRDEVLFNNWESLFSGTEAQLRAATHILSFNGKDILRD STWPQKSVWHGSDSKGRRLTENYCETWRTDSSVVTGQASSLSSGKLLEQKASSCQNAFIVLCIENSFMTS SKK >XP_020730828.1 collagen alpha-1(XVIII) chain [Odocoileus virginianus texanus] MAPDPSSRRRGHHGLLLFACCLSAAQADLLSWLWPGNSAQPTAAPASKPRGSSPVWPTEATTTHMAPRDA PTDWWKDSASPTAPLGRLEAGQGQSPAGPMASTASLDLKEENIAGVGAKILNVAQGIRSFVQLWDDAKDT TPAESSGRAGTPAPATPADSLSTAPAEGSGRAGMPPPADTTDPLSTPGPSSTPQDSGTTLQPSTGALSSP DTQRTEASTLPVPTQLPPSLGRPWFRESLVPPTPEGEVVEVGLQQLLGEPPPWQVAVVHDPDVGPAYEFG EDGSGGGQAARRLLPSAFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTAARGGRQHVQLLYT EPGATHTGTAASFELPALDGRWTRLALSVDGAYARLFVDCQEVQGQPLAQSLHDLHLEPDARLFVAQAGG ADPEKFQGLISELRLRRDPRVSPRHCQDEDEDDDDDGASGDLGSGLVETQEHLREELGASLGPRLPEAPP VTSPPLAGAGNEEDLRTEEVEESTTVSSLGAQTFPSLGTVSTWDESVWKPGSSMKERGLKGQKGEPGAQG PPGPIGPQGPAGPAIDSHKGQPVSGPQGPPGPPGPPGKDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPG DVGPKGEKGDPGVGPRGPPGPQGPPGPPGPSFKPDRLTFIDMEGSGFGGDLESLRGPRGFPGPPGPPGVP GLPGEPGRFGMNSSDVPGPAGLPGVPGRDGPPGLPGPPGPPGTPGKDGQPGLTGQKGSLGEAGAPGPKGS KGDPGPIGAPGEHGLAGAPGPAGPPGPPGPPGPPGPGFAAGFDDMEGSGNVFWSTARGADGLQGPPGTPG VKGDPGAVGPPGSKGEVGADGSPGLPGLPGREGAAGPQGPKGEKGTQGEKGDPGKDGVGQPGLPGPPGPP GPVVYVSEQDRVLASVPGPEGRAGFAGFPGPAGPKGDLGAKGQQGIPGPKGEKGEPGTFFGPDGRTLTPA QKGAKGEPGFRGPPGPYGRPGHKGEIGFPGRPGRPGMNGLKGEKGEPGDASVGFGMRGPPGPPGPPGPPG PPGTPVYDSNAFVDSGRPGPPGLPGHQGPSGPKGDKGDVGPPGPPGQFPFDLLQLGAEIKGEKGDRGAAG QKGERGEPGGGGFFGSGVPGPPGPPGYPGIPGPKGESIRGQPGPPGPQGPPGTGYEGRQGPPGPPGPPGP PGPPSFPGPYRQTISVPGPPGPPGPPGPPGSMGTSSGVRVWATYQMLVEQVLQVPEGWLIYVADREELYV RVRNGFRKVLDNEVAVLQPPLVQLHEGNPYPRREAPHPTARSWRADDILASPPRLPHPQPYPGAPHHGAY AHLRPVPPTASPSHTHHDFQPVLHLVALNSPQSGGLRGIRGADFQCFQQARAAGLAGTFRAFLSSRLQDL YSIVRRADRATLPVVNLRVCARPCLGLTSGDSCPRLRGALVAHQLGEVAGSPQAVMLCCGSHPRTRALHR AVFCGSFPEQNSAF >XP_040213558.1 collagen alpha-1(XVIII) chain isoform X1 [Rana temporaria] MARARLCPVLAVLLLVVTLPALSQAQFLNWLGWGAKPTILATPTAKITTDSAILATTTTAAPNSSATSSP EGSSLPAAVTVVDNETSSTGRDEKDLTPATSPSSQPAATASLSAGVSSPSNQTSVPAAAATTNPNALTTH KQPVGTGTTEASLNRQLRIPESPETVKKPPENQIFSIFQVQEEELSSGSDAQPATPTSKNVPTSAPEAST THKSEDKNIAGVGAEILNVAENIRNFMNVWEEKAKDLMTSTDNPPAEQGLGELINMTLPTNQSGDLSQYG TGQADSANTTETHARSQLALSNNQTLNVTQVPSGNVTSAQPDRENVEVGLLQLIGDPPPEEITKIFGPDR TPGYVFGEDANTGQVAQYHLPSPMFRDFSILFHIQPTTTKAGMLFSITDASQSIVYIGVKLSEVKDGKQQ IIFFYTEPGSTVTFPAATFSVPALTNQWTRFALSVEEEEVALFMECNELKRVRFERSPDEMELEDGSGLF VAQAGGADPDRYQGVIAEIKIKNDPRAAELQCEEEGDDSDGASGDFGSGLSEEEVVEVTRAPKVIAVAPM TVPPIQRPSVVNEPKVIKEVQETIQRVEVSGKPGQKGEKGDLGDRGMKGEIGPFGPKGEIGDSTSAGIGP KGDKGQKGELGVKGDAGFGYNGPKGQKGDPGASGPPGPPGVSGPSVVQKADGSTVQQITGPRGPPGPEGP PGKEGEPGDPGEDGKAGEVGPQGFPGTPGDAGKKGDKGDPGVGLRGPPGLPGPPGPPGPGTKTDKLTFID MEGSGYGPDLENFRGPSGLPGPPGPPGVPGLPGVPGTFGGNSTAIPGPPGLPGRPGQDGMAGPPGPPGLP GKDGNPGTAGLAGERGTDGDIGLPGAPGSKGSTGEPGIPGTPGETGLAGLPGPIGPRGLPGPPGPPGPSG RGTADGFDDMEGSGITFGGRAIQGRPGIPGEKGDAGFTGPKGDRGIPGLDGRPGLDGFPGPEGQKGNRGD QGERGEPGRDGIGIPGPPGPPGQIIYRSSDGADIIGGIGEGTRGYKGETGEQGYPGLPGLKGDKGEAGRI LGPDGSLFTGGVKGDTGPRGPSGPMGPVGPSGQKGEIGFPGRPGRPGVNGLKGEKGETADPTGYGIRGPA GPPGPPGPPGQAVYGDPRAAGPQGYPGQKGERGIPGTKGDQGDVGPAGPPGTFPYDFSSFGRGEKGEKGE PSVGDGQGIQGPPGNPGYPGLPGAKGDSIQGPPGPRGPPGAAGVGYEGRQGPPGPPGPPGAPAQQVYPGP GPNRPVLSVPGPPGPPGPPGPQGGSGGYSSATVLQTFQTMINLRQSLQEGTIVLVLETADLYVRVRDGFR KILLGEYVTGNGQGNEIAAKEPPVVIYPSGNRDSGSYQSTDEYEPPRNERPPPVNPRPPQPPPQVFPKPE PEDNVPVHTHQEYQAALHLVALNAPLTGSMRSIRGVDFQCFEQARKAGLHGTFRAFLSSRLQDLYSIVRK ADRLSVPIVNLRDEPLFDNWEALFGSEGQMNPGARIYSFEGRDVATDSTWPQKMIWHGSDAKGRRLTESY CETWRTDEGIVTGQASSVTNGKLLEQRPQSCNKNFIVLCIENSFMPAGQK >XP_030830245.1 collagen alpha-1(I) chain isoform X3 [Strongylocentrotus purpuratus] MLLRPYSGSRGTVFGVTDPYHQTIILSVNITSMSIEQMRISLILTNIDYTSESTEVAAFLVPSFTNHWTQLALSIRDNQV TLFLDCQELGMQFFDKNQGWHIRIPQMAPLFIGHLGTVGERVQYRGDIQQIIITNSADSAEEHCPIGEISGSGSMALRES AGEDWAFVFSGSGDEPTSMPEMPITYFTQYDAETPSTPANNVRLPASVQPPLEQVATILPKAPPTTPTLQATPSSQPAVV VPPGDSMKGQKGEEGWPGVNGIHGNPGVPGPRGVGGETGPEGPEGPMGPKGEKGDLGDAGPVGPLGEEGFPGVAGPPGDP GVKGEEGDQGMTGATGAKGEPGVGVPGLPGVAPTLSSEYMMRLGGEKGDPGRDGYPGVPGVQGPMGIPGVDGIGVPGPKG DKGEVGLGLPGSQGKPGKEGPKGETGQRGLPGPSSLESFIEGSGLEMFVGPPGQPGSPGRPGVMGPHGPRGESGLDGIPG LDGVPGQPGPAGRDGEPGPKGEPGALTEEEILDEIANLTAEFEMEGLSGMDGFNGSRGPPGVPGAVGPKGDSGMDGNPGM KGERGSSGLPGLEGPEGMKGGPGQNGIPGVPGIAGIPGESGQNGARGAPGPAGPPGPPGPSPLLPPGFPWTNMALNQDQE GSADGSGVWSGTVPPYLMGSPGVQGPPGPEGMQGEPGLVGEPGIPGEPAIPGMPGLTGERGERGLPGPRGMEGETGMDGA AGQKGDTGDPGVPGQPGADGFPGPRGVGVQGPPGDRGLPGPRGIQGLKGDVGEQGPACEIPPEILALSEHFAGVGSGDIG GGMMTRAPQELTSTKGEKGDIGFDGVPGMDGQQGAKGYPGPRGPGGVVGPKGNNGTQGEKGDVGAVGYAGPRGVKGDKGD MFLPTEEEMLMLKGDGGDTGRRGKKGLKGQFGIPGRPGRVGKTGPEGQTGPEGPVGPQGPPGPSGGGEGTCECDPAAFPP AFFPPGEKGSMGAPGSPGPMGPDGVPGAPGLPGVQGLRGLQGYAGEPGIEGLEGRPGAQGVPGVPGIDGARGEKGDPGDF FVNDEVFIGPPGEQGLPGRDGQPGQSIKGDTGEPGHGAEGMPGRDGRDGSQGPPGPPGMPGHPGEPAYYTGDGNGERGPK GEPGEPGREGQSGAPGFDGRPGSRGPRGPQGPTGYGEQGPPGEPGTPGEPGRGSIGHLGGGDYVGMARFATIQDMLDGMR DLEVGTLAFIIRVQELYIRVETGMQQVLLGATFTLPPTSEPRPQPRPQPRPQPSITSRTTTTTLIPTTTLAPFVDPTEPP QIPGPGLTDRTEEPILPGPEIPVSDQPMLYMYALNTPQEGYMIGGISGADFKCWKQAKAAGLKGTYRAFLSSPLQDIRTI VRKQDKGLPIANGKQEVLFNSWDDIFSTENEAPFHDSFHIYSFDGKDVMTDETWPDKYMWHGSYANGERMAESFCEAWRA QNHFARGQASPLSDHKLLGQDEFPCNNAFAVLCVQTARPNARK >AEL31277.1 multiplexin collagen isoform Ap3 [Drosophila melanogaster] MRVLQGVMFALAMICTLLVPVLGSFELVGQSIKDALAEYTLTDIMNNNQFAGIEFGEAEDGFPAFRFLQTADVKSPYRML LPEKLYEFAILITFRQSSLKGGYLFSVVNPLDTVVQLGVHLSPVVKNSYNVSLVYTQADQNIGRKLASFGVAHVPDKWNS IALQVLSDKVSFYYDCELRNTTLVTREPIELVFDSASTLYIGQAGSIIGGKFEGYLEKINVYGNPDAINVTCMPPPKATI APTTADDGSIFYEGSGENILFEDSTEANILSDDFWNTGDEATDIFDASGMQPPGQTQYNKHEETLGLVDGEEPYFSASSS NMNMKIVPGAVTFQNIDEMTKKSALNPPGTLAYITEEEALLVRVNKGWQYIALGTLVPIATPAPPTTVAPSMRFDLQSKN LLNSPPPLLNTPTFTTAPEYETWYPRMLRVAALNEPSTGDLQGIRGADFACYRQGRRAGLLGTFKAFLSSRVQNLDTIVR PADRDLPVVNTRGDVLFNSWKGIFNGQGGFFSQAPRIYSFSGKNVMTDSTWPMKMVWHGSLPNGERSMDTYCDAWHSGDH LKGSFASNLDGHKLLEQKRQSCDSKLIILCVEALSQDRKRKKREIGDGSSHGESESREFKTADEYAAHLENLLL >PNJ05978.1 COL18A1 isoform 2 [Pongo abelii] MAPDPRGCRILLLLFCSLAAARADLLNLNWLWFNNEDTSHAATTIPEPQGPLPAQPTHMAPRNGSTEPATVPGSPEPPSE LLEDGQDTPTSAESPDTPEENIAGVGAKILNVAQGIRSFVQLWNDTVPTESLTRAETLVLETPVGPFALPGPSSTPQENG TTLWPSRGTPSSPGAHTTEAGTLPAPTPSPPSLGRPWAPLTGPSVPPSSSERVSEEVGLLQLLGDPPPQQVTQTDDPDVG LAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAVVLLGVKLSGVQDGHQDISLLYTEPGAG QTHTAASFRLPAFVGQWTHLALSVEGGYVTLYVDCEEFQRMLLARSSRGLELEPGAGLFVAQAGGADPDKFQGMIAELKV RGDPQVSPMHCLDEEGDDSDGASGDFGSGLGDARELLREETGAALKPRLPMPPPVTTPPLAGGSSTEDSRSKEIEEQTTV ASLGGQTLPGSDSVSTWDGSVRTPGDRVREGGLKGQKGEPGVPGPPGRAGPPGSPCLPGPPGLPCPVSPLGPAGPASPLG PAGPALQPVPGPQGPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGP PGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGLFGVNSSDVPGPAGLPGVPGREGPPGFPGL PGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGDPGPAGARGESGLAGSPGPAGPPGPPGPPGPPGPGLPAGFDDMEG SGGPFWSTARSADGPQGPPGLPGLKGDPGMPGLPGAKGEVGADGAPGFPGLPGREGIAGPQGPKGDRGSQGEKGDPGKDG VGQPGLPGPPGPPGPVVYVSEQDGSVLSVPGPEGRPGFAGFPGPAGPKGDLGSKGERGSPGPKGEKGEPGSIFRPDGGAL GPVQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVY DSNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFPFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSR LPGPPGPPGPPGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPGPPSFPGPHRQTISVPGPPGPPG PPGPPGTVGASSGVRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVRNGFRKVQLEARTPLPRGTDNEVAALQPPVVQ LHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHTHRDFQPVLHLVALNSPLS GSMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARI FSFDGKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEAPSATGQASSLLGGRLLGQNAASCHHAYIVLCIENSFMT ASK >XP_043330533.1 collagen alpha-1(XVIII) chain isoform X5 [Cervus canadensis] MGSWLLAGDGWGSGRRSGLAPPPDSRGRLLLRGAHSPMAPDPSSRRRGHYGLLLLACCLSAAQADLLSWLWPGNSAQPTA APASKTPGSSPVWPTEDTTTHVAPRDAPTDWWKVSASPTTPLQRPEAGQGQSPAGPTASTASLDLKEENIAGVGAKILNV AQGIRSFVQLWDDTKDTTPAESSARAGTPAPTTPTDPLSTAPAKGSARAGMPPPTDTTDPLSTPGPSSTPQDSGTTLQPS TGALSSPDTQRTEAGTLPVPTQLPPSLGRPWFRESLVLPTPEGEVMEVGLQQLLGEPPPWQVAVVHDPDVGPAYEFGEDG SGGGQAARGFLPSAFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTAARGGRQHVQLLYTEPGDTHTRTAASF ELPALDGRWTRLALSVDGAYARLFVDCKEVQGQPLAHSLHDLHLEPDARLFVAQAGGADPEKFQGLISELRLRRDPRVSP RHCQDEDEDDDDDGASGDLGSGLVETQEHLREELGASLGPRLPEAPPVTSPPLAGVGNEEDLRTEEVEESTTVSSLGAQT LPSLGTVSMWDKSVWSPGSSMEERGLKGQKGEPGAQGPPGPIGPQGPAGPAIESHEGQPVSGPQGPPGPPGPPGKDGTPG RDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGEKGDPGIGPRGPPGPQGPPGPPGPSFKPDRLTFIDMEGSGFGGDLES LRGPRGFPGPPGPPGVPGLPGEPGRFGMNSSDVPGPAGLPGVPGRDGLPGLPGPPGPPGTPGKDGQPGLTGQKGSLGEAG APGPKGSKGDPGPIGAPGEHGLAGAPGPAGPPGPPGPPGPPGPGFAAGFDDMEGSGNVFWSTARGADGLQGPPGTPGVKG DPGAVGPPGSKGEVGADGAPGLPGLPGGEGAAGPQGPKGEKGTRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDRVL ASVPGPEGRTGFAGFPGPAGPKGDLGAKGQQGIPGPKGEKGEPGTFFGPDGRALTPAQKGAKGEPGFRGPPGPYGRPGHK GEIGFPGRPGRPGMNGLKGEKGEPGDASVGFGMRGPPGPPGPPGPPGPPGTPVYDSNAFVDSGRPGPPGLPGHQGPSGPK GDKGDVGPPGPPGQFPFDLLQLGAEMKGEKGDRGAAGQKGERGDPGGGGFFGSSVPGPPGPPGYPGIPGPKGESIRGQPG PPGPQGPPGIGYEGRQGPPGPPGPPGPPGPPSFPGPYRQTISVPGPPGPPGPPGPPGSMGTSSGVRVWATYQMLVEQVLQ VPEGWLIYVADREELYVRVRNGFRKVLLEAHVPLPHGTDNEVAVLQPPLVQLHEGNPYPRREAPHPTARSWRADDILANP PRLPHPQPYPGAPHHGAYAHLRPVPPTASPSHTHHDFQPVLHLVALNSPQSGGLRGIRGADFQCFQQARAAGLAGTFRAF LSSRLQDLYSIVRRADRATLPVVNLRDEVLFPSWEALFSGSEGQLKPGARIFSFDGRDVLQHPAWPQKSVWHGSDPSGRR LTESYCETWRTDTRAATGQASSLLAGRLLEQKAAGCHNAFIVLCIENSFMTSSSK >XP_043729625.1 collagen alpha-1(XVIII) chain isoform X5 [Cervus elaphus] MGSWLLAGDGWGSGRRSGLAPPPDSRGRLLLRGAHSPMAPDPSSRRRGHYGLLLLACCLSAAQADLLSWLWPRNSAQPTA APASKTPGSSPVWPTEDTTTHVAPRDAPTDWWKVSASPTTPLQRPEAGQGQSPAGPTASTASLDLKEENIAGVGAKILNV AQGIRSFVQLWDDTKDTTPAESSARAGTPAPTTPTDPLSTAPAKGSARAGMPPPTDTTDPLSTPGPSSTPQDSGTTLQPS TGALSSPDTQRTEAGTLPVPTQLPPSLGRPWFRESLVLPTPEGEVMEVGLQQLLGEPPPWQVAVVHDPDVGPAYEFGEDG SGGGQAARGFLPSAFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTAARGGRQHVQLLYTEPGDTHTRTAASF ELPALDGRWTRLALSVDGAYARLFVDCKEVQGQPLAHSLHDLHLEPDARLFVAQAGGADPEKFQGLISELRLRRDPRVSP RHCQDEDEDDDDDGASGDLGSGLVETQEHLREELGASLGPRLPEAPPVTSPPLAGVGNEEDLRTEEVEESTTVSSLGAQT LPSLGTVSMWDKSVWSPGSSMEERGLKGQKGEPGAQGPPGPIGPQGPAGPAIESHEGQPVSGPQGPPGPPGPPGKDGTPG RDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGEKGDPGIGPRGPPGPQGPPGPPGPSFKPDRLTFIDMEGSGFGGDLES LRGPRGFPGPPGPPGVPGLPGEPGRFGMNSSDVPGPAGLPGVPGRDGLPGLPGPPGPPGTPGKDGQPGLTGQKGSLGEAG APGPKGSKGDPGPIGAPGEHGLAGAPGPAGPPGPPGPPGPPGPGFAAGFDDMEGSGNVFWSTARGADGLQGPPGTPGVKG DPGAVGPPGSKGEVGADGAPGLPGLPGGEGAAGPQGPKGEKGTRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDRVL ASVPGPEGRTGFAGFPGPAGPKGDLGAKGQQGIPGPKGEKGEPGTFFGPDGRALTPAQKGAKGEPGFRGPPGPYGRPGHK GEIGFPGRPGRPGMNGLKGEKGEPGDASVGFGMRGPPGPPGPPGPPGPPGTPVYDSNAFVDSGRPGPPGLPGHQGPSGPK GDKGDVGPPGPPGQFPFDLLQLGAEMKGEKGDRGAAGQKGERGDPGGGGFFGSSVPGPPGPPGYPGIPGPKGESIRGQPG PPGPQGPPGIGYEGRQGPPGPPGPPGPPGPPSFPGPYRQTISVPGPPGPPGPPGPPGSMGTSSGVRVWATYQMLVEQVLQ VPEGWLIYVADREELYVRVRNGFRKVLLEAHVPLPHGTDNEVAVLQPPLVQLHEGNPYPRREAPHPTARSWRADDILANP PRLPHPQPYPGAPHHGAYAHLRPVPPTASPSHTHHDFQPVLHLVALNSPQSGGLRGIRGADFQCFQQARAAGLAGTFRAF LSSRLQDLYSIVRRADRATLPVVNLRDEVLFPSWEALFSGSEGQLKPGARIFSFDGRDVLQHPAWPQKSVWHGSDPSGRR LTESYCETWRTDTRAATGQASSLLAGRLLEQKAAGCHNAFIVLCIENSFMTSSSK >KAB0373800.1 hypothetical protein FD755_014056 [Muntiacus reevesi] MAPDPSSRRRGHHSLLLLACCLSAAQADLLSWLWPGNSAQPTAAPASKTLGSSPVWPTEDTTTHVDPRDAPTDWWKVSAS PTTPLQRPEAGQGQSPAGPTASTASLDLKEENIAGVGAKILNVAQGIRSFVQLWDDAKDTTPAESSARAGTPAPTTPTDP LSTAPAKGSARAGMLPPTDTTDPLSTPGPSSTPQDSRTTLQPSTRALSSPDTQRTEADTLPLPTQLPPSLGRPWFRESLV PPTPEGEVVEVGLQQLLGEPPPWQVAVVHDPDVGPAYEFGEDGSGGGQAARGLLPSAFFQDFSLLVRVRPASARAGVLFA VTDPAQAVVSVGVKLTAARGGRQHVQLLYTEPGDTHTRTAASFELPALDGRWTRLALSVDGAYARLFVDCKEVQGQPLAH SLHDLHLEPDARLFVAQAGGADPEKFQGLISELRLRRDPRVSPRHCQDEDEDDDDDGASGDLGSGLMETQEHLREELGAS LGPRLPEAPPVTSPPLAGVGNEEDLRTEEVEESTTVSSLGAQTLPSLGTVSTWDESVWSPGSSMKERGLKGQKGEPGAQG PPGPIGPQGPAGPAIESHEGQPVSGPQGPPGPPGPPGKDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGEKGD PGVGPRGPPGPQGPPGPPGPSFKPDRLTFIDMEGSGFGGDLESLRGPRGFPGPPGPPGVPGLPGEPGRFGMNSSDIPGPA GLPGVPGRDGPPGLPGPPGPPGTPGKDGQPGLTGQKGSVGEAGAPGPKGSKGDPGPIGAPGEHGLAGAPGPAGPPGPPGP PGPPGPGFAAGFDDMEGSGNVFWSTARGADGLQGPPGTPGVKGDPGAVGPPGSKGEVGADGAPGLPGLPGREGAAGSQGP KGEKGTQGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDRVLASVPGPEGRAGFAGFPGPAGPKGDLGAKGQQGIPGPK GEKGEPGAFFGPDGRALTPAQKGAKGEPGFRGPPGPYGRPGHKGEIGFPGRPGRPGMNGLKGEKGEPGDASVGFGVRGPP GPPGPPGPPGPAGTPVYDSNAFVDSGRPGPPGLPGHQGPSGPKGDKGDVGPPGPPVLLLQVGEIRSSSWTPGHCQPKGDR GQGSGGGASSSLPFKLSKAEGRGQHGARPTCWEVGQAEGGQTCGVRTCESGKGQAGRTAVTAAPPPALGPPGTASPCGVM GTGSGQRVWATYQMLVEQVLQVPEGWLIYVADREELYVRVRNGFRKVLLEAHVPLPHGTDNEVAVLQPPLVQLHEGNPYP RREAPHPTARAWRADDILANPPRLPHPQPYPGAPHHGAYAHLRPVPPTASPSHTHHDFQPVLHLVALNSPQSGGLRGIRG ADFQCFQQARAAGLAGTFRAFLSSRLQDLYSIVRRADRATLPVVNLRDEVLFPSWEALFSGSEGQLKPGARIFSFDGRDV LQHPAWPQKSVWHGSDPSGRRLTESYCETWRTDTRAATGQASSLLAGRLLEQKAAGCHNAFIVLCIENSFMTSSSK >KAB0366097.1 hypothetical protein FD754_010253 [Muntiacus muntjak] MAPDPSSRRRGHHSLLLLACCLSAAQADLLSWLWPGNSAQPTAAPASKTPGSSPVWPTEDTTTHVDPRDAPTDWWKVSAS PTTPLRRPEAGQGQSPAGPTASTASLDLKEENIAGVGAKILNVAQGIRSFVQLWDDAKDTTPAESSARAGTPAPTTPTDP LSTAPAEGSARAGMPPPTDTTDPLSTPGPSSTPQDSRTTLQPSTRALSSPDTQRTEAGTLPLPTQLPPSLGRPWFRESLV PPTPEGEVVEVGLQQLLGEPPPWQVAVVHDPDVGPAYEFGEDGSGGGQAARGLLPSAFFQDFSLLVRVRPASARAGVLFA VTDPAQAVVSVGVKLTAARGGRQHVQLLYTEPGATHTRTAASFKLPALDGRWTRLALSVDGAYTRLFVDCKEVQGQPLAH SLHDLHLEPDARLFVAQAGGADPEKFQGLISELRLRRDPRVSPRHCQDEDEDDDDDGASGDLGSGLMETQEHLREELGAS LGPRLPEAPPVTSPPLAGVGNEEDLRTEEVEESTTVSSLGAQTLPSLGTVSTWDESVWSPGSSMKERGLKGQKGEPGAQG PPGPIGPQGPAGPDIESHEGQPVSGPQGPPGPPGPPGKDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGEKGD PGVGPRGPPGPQGPPGPPGPSFKPDRLTFIDMEGSGFGGDLESLRGPRGFPGPPGPPGVPGLPGEPGRFGMNSSDIPGPA GLPGVPGRDGPPGLPGPPGPPGTPGKDGQPGLTGQKGSVGEAGAPGPKGSKGDPGPIGAPGEHGLAGAPGPAGPPGPPGP PGPPGPGFAAGFDDMEGSGNVFWSTARGADGLQGPPGTPGVKGDPGAVGPPGSKGEVGADGAPGLPGLPGREGAAGPQGP KGEKGTQGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDRVLASVPGPEGRAGFAGFPGPAGPKGDLGAKGQQGIPGPK GEKGEPGAFFGPGPRALTPAQNGAKGEPGFRGPPGPYGRPGHKGEIGFPGRPGRPGMNGLKGEKGEPGDASVGFGVRGPP GPPGPPGPPGPAGTPVYDSNAFVDSGRPGPPGLPGHQGPSGPKGDKGDVGPPGPPVLLLQVGEIRSSSWTPGHCQPKGDR GQGSGGGASSSLPFKLSKAEGRGQHGARPTCWEVGQAEGGQTCGVRTCESGKGQAGRTAVTAAPPPALGPPGTASPCGMM GTGSGQWVWATYQMLVEQVLQVPEGWLIYVADREELYVRVRNGFRKVLLEAHVPLPHGTDNEVAVLQPPLVQLHEGNPYP RREAPHPTARSWRADDILANPPRLPHPQPYPGAPHHGAYAHLRPVPPTASPSHTHHDFQPVLHLVALNSPQSGGLRGIRG ADFQCFQQARAAGLAGTFRAFLSSRLQDLYSIVRRADRAALPVVNLRDEVLFPSWEALFSGSEGQLKPGARIFSFDGRDV LQHPAWPQKSVWHGSDPSGRRLTESYCETWRTDTRAATGQASSLLAGRLLEQKAAGCHNAFIVLCIENSFMTSSSK >KAF4020675.1 hypothetical protein G4228_012853 [Cervus hanglu yarkandensis] MAPDPSSRRRGHYGLLLLACCLSAAQADLLSWLWPGNSAQPTAAPASKTPGSSPVWPTEDTTTHVAPRDAPTDWWKVSAS PTTPLQRPEAGQGQSPAGPTASTASLDLKEENIAGVGAKILNVAQGIRSFVQLWDDTKDTTPAESSARAGTPAPTTPTDP LSTAPAKGSARAGMPPPTDTTDPLSTPGPSSTPQDSGTTLQPSTGALSSPDTQRTEAGTLPVPTQLPPSLGRPWFRESLV LPTPEGEVMEVGLQQLLGEPPPWQVAVVHDPDVGPAYEFGEDGSGGGQAARGFLPSAFFQDFSLLVRVRPASARAGVLFA VTDPAQAVVSVGVKLTAARGGRQHVQLLYTEPGDTHTRTAASFELPALDGRWTRLALSVDGAYARLFVDCKEVQGQPLAH SLHDLHLEPDARLFVAQAGGADPEKFQGLISELRLRRDPRVSPRHCQDEDEDDDDDGASGDLGSGLVETQEHLREELGAS LGPRLPEAPPVTSPPLAGVGNEEDLRTEEVEESTTVSSLGAQTLPSLGTVSMWDESVWSPGSSMKERGLKGQKGEPGAQG PPGPIGPQGPAGPAIESHEGQPVSGPQGPPGPPGPPGKDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGEKGD PGIGPRGPPGPQGPPGPPGPSFKPDRLTFIDMEGSGFGGDLESLRGPRGFPGPPGPPGVPGLPGEPGRFGMNSSDVPGPA GLPGVPGRDGLPGLPGPPGPPGTPGKDGQPGLTGQKGSLGSKGDPGPIGAPGEHGLAGAPGPAGPPGPPGPPGPPGPGFA AGFDDMEGSGNVFWSTARGADGLQGPPGTPGVKGDPGAVGPPGSKGEVGADGAPGLPGLPGGEGAAGPQGPKGEKGTRGE KGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDCGQPLRGVVLTVLSPQGRTGFAGFPGPAGPKGDLGAKGQQGIPGPKGEK GEPGTFFGPDGRALTPAQKGAKGEPGFRGPPGRPGMNGLKGEKGEPGDASVGFGMRGPPGPPGPPGPPGPPGTPVYDSNG EKGDRGAAGQKGERGDPGGGGFFGSSVPGPPGPPGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPP GPPSFPGPYRQTISVPGPPGPPGPPGPPGSMGTSSGQVRVWATYQMLVEQVLQVPEGWLIYVADREELYVRVRNGFRKVL DNEVAVLQPPLVQLHEGNPYPRREAPHPTARSWRADDILANPPRLPHPQPYPGAPHHGAYAHLRPVPPTASPSHTHHDFQ PVLHLVALNSPQSGGLRGIRGADFQCFQQARAAGLAGTFRAFLSSRLQDLYSIVRRADRATLPVVNLRDEVLFPSWEALF SGSEGQLKPGARIFSFDGRDVLQHPAWPQKSVWHGSDPSGRRLTESYCETWRTDTRAATGQASSLLAGRLLEQKAAGCHN AFIVLCIENSFMTSSSK >NP_001082208.1 collagen type XVIII alpha 1 S homeolog precursor [Xenopus laevis] MILRCTWVLLLYAAYHALLVSSQGKDNFGLEVGLLQLIGEPVPSQITKVLGPDKTPAYVFDKEANTGQVAQYHLPNPMYR DFSLLFHVQPTTNKAGILFAITDASQXIVYIGVKLSEAKDGKQDIIFYYTEPGSRDSYIAATFNVPSLVNRWSRFSISVE DEEVVLFMNCDEMERVRFERSPDEMELEDGSGLFVAQAGGADPDRYQGVIADLKIVADPRAAEQQCEDDGDDSDGISGDF GSGIADNDLVTASPPVVIKVQPPINVPPIQKNPVEKEIVQTGQGQQGIKGEKGDRGEKGERGLTGPKGDSASVSLASDSK AEKGQKGEVGFKGSAGFGYPGPKGQKGDPGIMGPRGHPGPPGPSVLQKSDGTTVQQVTGPPGPQGPAGPPGNDGEPGDPG EDGKTGEVGPQGFPGTPGDIGQKGEKGDSGVGMRGPSGPPGPPGPPGPSRMDKLTFIDMEGSGYGGDLENVRGPSGLPGP PGPPGVPGLPGVPGTFGMNNTGLPGPPGLPGLPGKEGFPGPPGPSGPPGKDGLTGAAGVAGIRGEDGEIGLPGAPGVKGS PGEPGQPGAVGQPGLAGLPGPMGPRGLPGPPGPPGPVGRGSAIGFDDMEASGLGFGPREGTQGLSGLPGAKGEQGNPGMP GLPGVKGESGSPGPEGRQGLDGFPGLEGLKGEKGEHGERGEPGRDGVGIPGPPGPPGQVLYLPSDDKSAVGAISGPEGRQ GVAGLPGPRGPKGDQGLDGFPGTSGAKGERGEPGLIMRPDGTIYTDLSKAEKGEQGPTGPAGSVGPSGQKGEIGFPGRPG RPGMNGLKGEKGDPASGGFGLNGPPGPPGPPGPPGSVVYGDPNIPRAYPGQKGERGFPGPKGDVGPAGPPGSFPYDLSTF ASILTREAGLKGEKGEPGGGDNGQGIPGPSGNPGYPGLPGAKGESVQGPPGPAGPPGHPGTGYEGRQGPPGPPGPPGLPG SSSSYPGPHRQTISIPGPPGPPGPPGLPGTSGGLSGATVLQTYQTMINLAHRLQEGTIVLVQERAELYVRVREGFRKILL GEYSALSGPGQDNEVAAEQAPVVPYPHRNKDSDYLQSTEENSNNANVPSGARPWSDPRLPEPPRVDPPRVDPPPPDHHHH GNPHPLEPSPVHTHQQFNPALHLVALNAPLSGSMKSIRGVDFQCFEQARKSGLHGTFRAFLSSRLQDLYSIVRRADRQSV QIVNLRDEVLYDNWESLFSGSEAQMRPGARIFSFDGKDVATDPTWPQKMVWHGSDAKGRRLTESYCETWRTDESAVTSQA SSLTSGKLLEQRPQSCNKNFIVLCIENSFMTNNRK >XP_015820964.1 PREDICTED: collagen alpha-1(XVIII) chain [Nothobranchius furzeri] MNMRCSSWLERLVCCVLLLIPAATQREDNGVSLLQLIGDPPPDGIPQVDGPDNNPGYVFGPDTSSGQMALAHFPSSFYRN FALIFSVKPTSDQGGVIFSITDSSQEVIDVGVRLAAVQGGHQDVIFYYNYLGKKNSHEAARFPVPSMKDTWNWFAIAVQD DKVMFYHSCEGEPQVMRMERSADKLELESGAGVFVGGAGGSTHDKFEGVISELRVVGDPRAAERLCEEEDDDSDMASGEG SGVEGSEVPNRYREKHRYTTTTPSLPPIPQPPLNRKGEEATVRESGAVGAKGEKGERGDRGEKGDRGAIGPKGEAGSGFG SRGGIRGEKGEPGERGLKGNAGFGYPGKKGDPGPPGVPGPPGPPGPAAEYSVASDGSVVSRVPGPRGPPGAPGSQGPPGE DGEPGDPGEDGKTGPQGPPGFPGTPGDSGQKGEKGDRGEGQPGPRGLPGPPGAPGPGYRSTFEDMEASGFSDLETVRGPR GPPGPPGPPGPPGPSTSGSTSNSGAFGPPGKDGAPGLPGSPGLPGSDGPPGAPGPRGEKGDSGELGLPGAIGQKGAQGDL GLPGPPGEPGLAGLPGPMGPVGPPGPAGPPGPSYRVGFDDMEGSSGLTGIRGPEGIQGSPGLPGHPGEPGLPGADGPKGD QGPTGKDGLPGLDGFPGPPGQKGDRGDKGETGDPGRDGTGLPGPPGPPGPPGQIIYQPSDRVRNLDNFAGGAQGGLGLPG RAGLPGPVGPKGERGDPGPAGYGVKGEKGEPGLIIGPDGAPLYLGGLTGQKGDRGPAGPVGPSGPYGPPGLKGEIGMPGR PGRPGVNGYKGEKGEPGGGAGYGYPGVAGPPGPPGPPGPPGPAIPLDRYNAYDEASRSYRVVKGDKGERGDRGPPGTVSN FDIYTLKNQLKGDRGDTGVKGEKGEPGHGYYDPRIEGLQGPPGPPGNPGLPGPKGDSIVGPSGPQGPPGPPGVGYDGRPG PPGPPGPPGPATSPSFTGTHRPHYPVSVPGPPGPPGPPGNPGLSSGVTVLRSYDTMIATARQQPEGSLIYIIDKADLYLR VREGLRQVMLGQYSPFSRDLENEVVEVQPPPVIVYPHNSQNNGAGHYSDSGSVIRPIEPPQPRPHQPVPGSTGLVETPES VLHLAALNAPQTGDMRGIRGADFMCFQQARAVGLKGTFRAFLSSKLQDLYTIVRTLDRKTFPIVNLKNQVLFTSWESIFR ENSSKMRENVPIYSFDGRDVLRDSAWPEKMVWHGSSSEGKRNMDHYCETWRIDNHALTGLASSLQSGYLLQQNRSSCSGS YIVLCIENAFMSSSKK >XP_030285041.1 collagen alpha-1(XVIII) chain isoform X1 [Sparus aurata] MRTQFGVLLLLALWVVHTDAWFWSWTGTTTLPPTVDNEGSGSQAGSGEPPSENIARTGLEIIDEGHGIQKVVQTETTQAP RLTTTTQPANEHASEKGAAGISSRKHKPEDSGVSLLQLIGDPPPSEIRRVYGFDNIPGYDFGPDANTGQLARAHLPSPFF RDFALIFYLKPTTDRGGVIFSVTDASQKIMYVGVKLSAVQGGNQNVILYYTEPDSQQSYEAARFRVPSMRDTWTRFAIAV RDEKVMFYHNCDADPQVMRIERSPDEMELEAGAGVFVGQAGGADPDKFLGVIGELRVVGDPRAAERHCEEDEDDSDMASG DGSGYVESKPPKPAVDNPRWTTTPPPSRPIQQPPVTKKEEVSVARETGPDGAKGEKGDRGDRGEKGERGPIGPKGESGFG SSSRGGARGEKGEPGEKGLKGSAGFGYQGTKGEPGPAGPPGPAGPPGPATEFSVGSDGSVSSRGPGPRGPAGPPGSPGPK GPPGNDGEPGDPGEDGKTGPEGPPGFPGTPGDTGPKGDKGDRGDGQPGPRGPPGPPGPPGTGLRSTFVDMEGSGFPDLDS IRGLPGPQGPPGPPGPPGPSTATTGLSSGAFGPPGKDGAPGQPGLAGLPGTDGLPGAPGPKGEKGDSGELGLPGAIGQKG AQGEPGVPGTPGEAGLAGLPGPMGPVGQPGPPGPPGPSYRVGFDDMEGSGGGFSNGLPGVRGPEGTQGSPGLPGLPGKPG FPGMPGQKGSEGSVGRDGQPGLDGFPGPKGPKGDKGDKGETGNPGRDGTGHPGPPGPPGPPGEIIYRTSDNLDVAAGGAG PQGGPGLPGQAGFPGPIGPKGDRGDPGPVGYGVKGEKGEPGLIVGPDGNLLSLEGLTGVKGDRGPAGPVGPTGPYGPPGL KGEIGMPGRPGRPGVNGYKGEKGEPSVGSGYGYPGVPGQPGPPGPPGPPGPAIPIDRFNRYDDSSRNYPATKGEKGERGD RGIPGIPGAASNFDIYAFKNELKGERGETGVKGEKGEPSGGYYDPRFGGVQGPQGPPGKPGLPGPKGEPVMGPPGPQGPP GSPGIGYDGRPGPPGPPGPPGPQSPSLPGAGAYRPNQPVSVPGPPGPPGPPGSPALSSGVSVLRSYDVMIATARRQAEGS LIYIIDKADLYLRVRDGLRQVMLGEYSPFFRDLENEVAEVQPPPVILYPQSGDESQNNGAGHYSQGGSSIRPIEPPPQPP VEPRYPPQYDPRFPDPRRTGQTDGGLATRQTENRYPVTPQRRPSPPVVHPVGHVDTSVSGLHLIALNAPQSGNMRGIRGA DFLCFQQARAIGLKGTFRAFLSSKLQDLHTIVRRSDRDSLPILNLKDQVLFSSWEAIFGDNASKMRENVPIYSFDGRDIL RDSAWPEKMVWHGSSNKGHRQTDHYCETWRAGDRAVTGLASSLQSGHLLQQSSTSCSGSYIVLCIENAFTTHSKK >XP_023806434.1 collagen alpha-1(XVIII) chain [Oryzias latipes] MRWNERLVCCVLLFVVPAALQWPEDNGVSLLQLIGDPPPSEISQVYGPDNAIGYVFGPDAKMGQLAVAHFPTPFYRDFSL NFHLKPTSNEGGVVFSITDSSQQVIVVGVKLSTVERQTQDVIFYYSETGSEQSYEAARFQVTSMTDTWTRFSISVRDDKV AFYFNCDLSPVVKRFERSPDDMELERGSGVFVGQTGGPDPERFLGVISELRVVGDPRAAETFCDEDGDDSDMASGEGSGY EETRPQKQNMDRNRFSTAPPFPSFMSIQKPPLATSGEEAVVRDTAIKSEHMSVFVESGSRLHGSAGAVGAKGEKGERGER GEKGDRGPAGPKGDSGPGSSSASGSRGEKGEPGEKGTKGSAGFGYQGKKGDPGQPGPPGPPGPPGPSTEYVPSSDGTVVS KVQGPRGPPGPPGPQGQPGEDGEPGDPGEDGKTGSPGPQGFPGTPGDPGRKGDKGDRGEGQPGPRGAPGPPGPPGPGMRS TFVDMEGSGFPDLESLRGLPGPPGPPGPPGPPGSSVTGPAMGSGAFGPPGRDGAAGQPGLPGTDGLPGAPGPKGDKGDAG DLGLPGAIGEKGDRGEPGLPGSPGESGLAGLPGPMGPVGPPGPPGPPGSNYRVGFDDVEASGGRFTSGLGIRGPQGAQGP PGLPGNPGRPGLPGVQGQKGREGPPGRDGQPGLDGFPGTPGQKGERGDKGDRGEAGRDGAGLPGPPGPPGPPGQIFYQPS DNFDAAFGRAGPQGGPGLPGQAGFPGPVGPKGDTGNPGLPGLGVKGEKGEPGLIIGPDGNPLYLGGLTGQKGDIGPQGPA GPMGPQGPPGLKGEIGMPGRPGRPGVNGYKGEKGEPSGGLGHGGVPGPPGPPGPPGPPGPPFAIDRFNRYDDISRNYPVK GEKGERGDPGFPGTASDFDIYTLKNQWKGERGDPGVKGEKGEPGAGHDPQYGALQGPLGPPGLPGPKGDSIMGPPGPQGP PGSPGIGYDGRPGPPGPPGPPGPPWSQTLPESYKPNYPVSVPGPPGPPGPPGHPGHSSGVMVLRSYDTLIATARSQEEGS LIYILDKADLYLRVRDGLRQVMLGEYNPFFRDFDNEVAEAQPPPVVLYPHSPDHSQNNGASQYSQGGSVIRPIETPPPVE RRYPPQYEPRFPDQQRPSQTDGRLINQPSDGKYAVTPQRRPNPPVPGPVETSTLGLRLIALNTPQSGNMKGIRGPDYLCF EQARAAGLRGTFRAFLSSKVQDLHTIVRHSDREKPPIVNLKNQVLFDSWQSIFGESVSKMRKNVPIYSFDGRDILRDSAW PEKMVWHGSSKKGHRQTDQYCEAWRAGDQAVTGLASSLQSSHLLQQTPTSCSRACIVLCIENAMVSPSK
Mafft alignment of selected proteins >sp|P39060|COIA1_HUMAN Collagen alpha-1(XVIII) chain OS=Homo sapiens OX=9606 GN=COL18A1 PE=1 SV=5 -------------------------------------MAPYPCG----CHILLLLFCCLA AARANLLNLNWL-W----------------------FNNEDTSHAATTIPEPQG-PLPVQ PT---ADTT----------THVTPRNGSTEP----------------------------- ATAPGSPEPPSELLE--------------------------------------------- --------------------DGQDTPT--------SAESPD------APEENIAGVG--- ---------AEILNVAKGIRSFVQLWN---DTVPTESLARAETLVLETP----------- ------------VGPLALAGPSSTPQENGTTLWPSRGIPSSPGAHT---TEAGTLPAPTP SPPSLGRPWAPLT---------GPSVPPPSSGRASLSSLLGGAPPWGSLQDP------DS QGLSPAAAAPSQQLQRPDVRLRTPLLHPLVMGSLGKHAAPSAFSSGLPGALSQVAVTTLT RDSGAWVSHVANSVGPGLANNSALLGAD-------PE-APAGRCLPLPPSLPVCGHLGIS RFWL---PNHLHHESGEQVRAGARAWGGLLQTHCHPFLAWFFCLLLVPPCGSVPPPAPPP CCQFCEALQDACWSRLGGGRLPVACAS-------LPTQEDGY-CVLIGPAA--------- ---------ERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDAN-SGQVARYHFP SLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYTEPGAG Q-THTAASFRLPAFVGQWTHLALSVAGGFVALYVDCE-EFQRMPLARSSR-GLELEPGAG LFVAQAGG-ADPDKFQGVIAELKVRRDPQVSPMHCL-------------DE-EGDD---S DGASGDSGSGLGDAR-ELLREETGAALKPRLP----APPPVTTPPLAG---------GSS TEDSRS-EEVEEQTTVAS--------------LGAQTLPG-------------------- ---SDSVSTWDGSVRTPGGRVKEG--------GLKGQKGEPGVPGPPGRAGPPGSPCLPG PPGLPCPV---------SPLGPA--GPALQTVPGPQ------GPPGPPGRDGTPGR---- --------DGEPGDPGEDGKPGDTGPQGFPGTP-----GDVGPKGDKGDPGV---GERGP PGPQGPPGP------PGPSFRHDKLTFIDMEGS-GFGGDLEALRGPRGFPGPPGPPGV-- -------------PGLPGEPGRFGVNSSD-VPGPAGLPGV-------------------- --------PGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGE------AGAPGHKGSK GAPGPAGARGESGLAGAPGPA---GP---PGPPGPPGPPGPG--LPAGF--------DDM EGS--GGPFWSTA-----RSADGPQGPPGLPGLKGDPGV------------PGLPGAKGE VGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYV SEQD------GSVL-SVPGPE---GRPGFAGFPGPAGP---------------------- -------------------KGNLGSKGERGSPGPKGEKGEPGS-----IFSPDGGALG-- --PAQKGAKGEPGFRGPP---------------------------GPYGRPGYKGEIGFP GRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPV----YDS-NVFAE SSRPGPPGL--PGNQGPPGPKGAKGEVGPPGPPGQF-----------------P-FDFLQ LEAEMKGEKGDRGDAGQKGERGEPG--GGGFFGSSLPGPPGPPGPPGPRGYPGIPGPKGE SIRGQPGPP-------GPQGPPGI-GYEGRQ---GPPGPPGPPGPP----SF-------- ------PG-PHRQ------------------------TISVPGPP--GPPGPPGPP---G T-------MGAS--SG---------V-RLWATRQAMLGQVHEVPEGWLIFVAEQEELYVR VQNGFRKVQLEARTPLPR--GTDNEVAALQPPVVQLHDSN------------PYPRREHP HPTA-----RPWRAD---------DILASPPRLPE-PQPYPGAP---------------- --HHSSYVHLRPARPTSPP----AHSHRDFQPVLHLVALNSPLSGGM-RGIRGADFQCFQ QARAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSG-SEGPL KPGARIFSFDGKDVLRHPTWPQKSVW-HGSDPNGRRLTES-YCETWRTEAPSATGQASSL LGGRLLGQSAASCHHAYIVLCIENSFMTASK----------------------------- ----- >sp|P39060-1|COIA1_HUMAN Isoform 2 of Collagen alpha-1(XVIII) chain OS=Homo sapiens OX=9606 GN=COL18A1 -------------------------------------MAPYPCG----CHILLLLFCCLA AARANLLNLNWL-W----------------------FNNEDTSHAATTIPEPQG-PLPVQ PT---ADTT----------THVTPRNGSTEP----------------------------- ATAPGSPEPPSELLE--------------------------------------------- --------------------DGQDTPT--------SAESPD------APEENIAGVG--- ---------AEILNVAKGIRSFVQLWN---DTVPTESLARAETLVLETP----------- ------------VGPLALAGPSSTPQENGTTLWPSRGIPSSPGAHT---TEAGTLPAPTP SPPSLGRPWAPLT---------GPSVPPPSS----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDAN-SGQVARYHFP SLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYTEPGAG Q-THTAASFRLPAFVGQWTHLALSVAGGFVALYVDCE-EFQRMPLARSSR-GLELEPGAG LFVAQAGG-ADPDKFQGVIAELKVRRDPQVSPMHCL-------------DE-EGDD---S DGASGDSGSGLGDAR-ELLREETGAALKPRLP----APPPVTTPPLAG---------GSS TEDSRS-EEVEEQTTVAS--------------LGAQTLPG-------------------- ---SDSVSTWDGSVRTPGGRVKEG--------GLKGQKGEPGVPGPPGRAGPPGSPCLPG PPGLPCPV---------SPLGPA--GPALQTVPGPQ------GPPGPPGRDGTPGR---- --------DGEPGDPGEDGKPGDTGPQGFPGTP-----GDVGPKGDKGDPGV---GERGP PGPQGPPGP------PGPSFRHDKLTFIDMEGS-GFGGDLEALRGPRGFPGPPGPPGV-- -------------PGLPGEPGRFGVNSSD-VPGPAGLPGV-------------------- --------PGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGE------AGAPGHKGSK GAPGPAGARGESGLAGAPGPA---GP---PGPPGPPGPPGPG--LPAGF--------DDM EGS--GGPFWSTA-----RSADGPQGPPGLPGLKGDPGV------------PGLPGAKGE VGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYV SEQD------GSVL-SVPGPE---GRPGFAGFPGPAGP---------------------- -------------------KGNLGSKGERGSPGPKGEKGEPGS-----IFSPDGGALG-- --PAQKGAKGEPGFRGPP---------------------------GPYGRPGYKGEIGFP GRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPV----YDS-NVFAE SSRPGPPGL--PGNQGPPGPKGAKGEVGPPGPPGQF-----------------P-FDFLQ LEAEMKGEKGDRGDAGQKGERGEPG--GGGFFGSSLPGPPGPPGPPGPRGYPGIPGPKGE SIRGQPGPP-------GPQGPPGI-GYEGRQ---GPPGPPGPPGPP----SF-------- ------PG-PHRQ------------------------TISVPGPP--GPPGPPGPP---G T-------MGAS--SG---------V-RLWATRQAMLGQVHEVPEGWLIFVAEQEELYVR VQNGFRKVQLEARTPLPR--GTDNEVAALQPPVVQLHDSN------------PYPRREHP HPTA-----RPWRAD---------DILASPPRLPE-PQPYPGAP---------------- --HHSSYVHLRPARPTSPP----AHSHRDFQPVLHLVALNSPLSGGM-RGIRGADFQCFQ QARAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSG-SEGPL KPGARIFSFDGKDVLRHPTWPQKSVW-HGSDPNGRRLTES-YCETWRTEAPSATGQASSL LGGRLLGQSAASCHHAYIVLCIENSFMTASK----------------------------- ----- >sp|P39060-2|COIA1_HUMAN Isoform 3 of Collagen alpha-1(XVIII) chain OS=Homo sapiens OX=9606 GN=COL18A1 -------------------------------------MAP-------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------------------------------RCPWPWP RRRRLLDVLAPLVLL------LGVRAASAEP----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ERISEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDAN-SGQVARYHFP SLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYTEPGAG Q-THTAASFRLPAFVGQWTHLALSVAGGFVALYVDCE-EFQRMPLARSSR-GLELEPGAG LFVAQAGG-ADPDKFQGVIAELKVRRDPQVSPMHCL-------------DE-EGDD---S DGASGDSGSGLGDAR-ELLREETGAALKPRLP----APPPVTTPPLAG---------GSS TEDSRS-EEVEEQTTVAS--------------LGAQTLPG-------------------- ---SDSVSTWDGSVRTPGGRVKEG--------GLKGQKGEPGVPGPPGRAGPPGSPCLPG PPGLPCPV---------SPLGPA--GPALQTVPGPQ------GPPGPPGRDGTPGR---- --------DGEPGDPGEDGKPGDTGPQGFPGTP-----GDVGPKGDKGDPGV---GERGP PGPQGPPGP------PGPSFRHDKLTFIDMEGS-GFGGDLEALRGPRGFPGPPGPPGV-- -------------PGLPGEPGRFGVNSSD-VPGPAGLPGV-------------------- --------PGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGE------AGAPGHKGSK GAPGPAGARGESGLAGAPGPA---GP---PGPPGPPGPPGPG--LPAGF--------DDM EGS--GGPFWSTA-----RSADGPQGPPGLPGLKGDPGV------------PGLPGAKGE VGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYV SEQD------GSVL-SVPGPE---GRPGFAGFPGPAGP---------------------- -------------------KGNLGSKGERGSPGPKGEKGEPGS-----IFSPDGGALG-- --PAQKGAKGEPGFRGPP---------------------------GPYGRPGYKGEIGFP GRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPV----YDS-NVFAE SSRPGPPGL--PGNQGPPGPKGAKGEVGPPGPPGQF-----------------P-FDFLQ LEAEMKGEKGDRGDAGQKGERGEPG--GGGFFGSSLPGPPGPPGPPGPRGYPGIPGPKGE SIRGQPGPP-------GPQGPPGI-GYEGRQ---GPPGPPGPPGPP----SF-------- ------PG-PHRQ------------------------TISVPGPP--GPPGPPGPP---G T-------MGAS--SG---------V-RLWATRQAMLGQVHEVPEGWLIFVAEQEELYVR VQNGFRKVQLEARTPLPR--GTDNEVAALQPPVVQLHDSN------------PYPRREHP HPTA-----RPWRAD---------DILASPPRLPE-PQPYPGAP---------------- --HHSSYVHLRPARPTSPP----AHSHRDFQPVLHLVALNSPLSGGM-RGIRGADFQCFQ QARAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSG-SEGPL KPGARIFSFDGKDVLRHPTWPQKSVW-HGSDPNGRRLTES-YCETWRTEAPSATGQASSL LGGRLLGQSAASCHHAYIVLCIENSFMTASK----------------------------- ----- >NP_034059.2 collagen alpha-1(XVIII) chain isoform 2 precursor [Mus musculus] -------------------------------------MAPR------------------- -------------W---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------HLLDV---LTSLVLL----------------------------------- ------------------------------------------------------------ ---------------------LVARVSWAEP----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ENVAEEVGLLQLLGDPLPEKISQIDDPHVGPAYIFGPDSN-SGQVAQYHFP KLFFRDFSLLFHVRPATEAAGVLFAITDAAQVVVSLGVKLSEVRDGQQNISLLYTEPGAS Q-TQTGASFRLPAFVGQWTHFALSVDGGSVALYVDCE-EFQRVPFARASQ-GLELERGAG LFVGQAGT-ADPDKFQGMISELKVRKTPRVSPVHCL-------------DE-EDDD---E DRASGDFGSGFEESS-KSHKEDT--SLLPGLP----QPPPVTSPPLAG---------GST TEDPRT-EETEEDAAVDS--------------IGAETLPG-------------------- ---TGSSGAWDEAIQNPGRGLIKG--------GMKGQKGEPGAQGPPGPAGPQG------ ------------------PAGPVVQSPNSQPVPGAQGPP---GPQGPPGKDGTPGR---- --------DGEPGDPGEDGRPGDTGPQGFPGTP-----GDVGPKGEKGDPGI---GPRGP P---GPPGP------PGPSFRQDKLTFIDMEGS-GFSGDIESLRGPRGFPGPPGPPGV-- -------------PGLPGEPGRFGINGSY-APGPAGLPGV-------------------- --------PGKEGPPGFPGPPGPPGPPGKEGPPGVAGQKGSVGD------VGIPGPKGSK GDLGPIGMPGKSGLAGSPGPV---GP---PGPPGPPGPPGPG--FAAGF--------DDM EGS--GIPLWTTA-----RSSDGLQGPPGSPGLKGDPGV------------AGLPGAKGE VGADGAQGIPGPPGREGAAGSPGPKGEKGMPGEKGNPGKDGVGRPGLPGPPGPPGPVIYV SSED------KAIV-STPGPE---GKPGYAGFPGPAGP---------------------- -------------------KGDLGSKGEQGLPGPKGEKGEPGT-----IFSPDGRALG-- --HPQKGAKGEPGFRGPP---------------------------GPYGRPGHKGEIGFP GRPGRPGTNGLKGEKGEPGDASLGFSMRGLPGPPGPPGPPGPPGMPI----YDS-NAFVE SGRPGLPGQ--QGVQGPSGPKGDKGEVGPPGPPGQF-----------------P-IDLFH LEAEMKGDKGDRGDAGQKGERGEPGAPGGGFFSSSV---PGPPGPP---GYPGIPGPKGE SIRGPPGPP-------GPQGPPGI-GYEGRQ---GPPGPPGPPGPP----SF-------- ------PG-PHRQ------------------------TVSVPGPP--GPPGPPGPP---G A-------MGAS--AG--------QV-RIWATYQTMLDKIREVPEGWLIFVAEREELYVR VRNGFRKVLLEARTALPR--GTGNEVAALQPPLVQLHEGS------------PYTRREYS YSTA-----RPWRAD---------DILANPPRLPD-RQPYPGVP---------H------ --HHSSYVHLPPARPTLSL----AHTHQDFQPVLHLVALNTPLSGGM-RGIRGADFQCFQ QARAVGLSGTFRAFLSSRLQDLYSIVRRADRGSVPIVNLKDEVLSPSWDSLFSG-SQGQL QPGARIFSFDGRDVLRHPAWPQKSVW-HGSDPSGRRLMES-YCETWRTETTGATGQASSL LSGRLLEQKAASCHNSYIVLCIENSFMTSFSK---------------------------- ----- >XP_021334397.1 collagen type XVIII, alpha 1 isoform X3 [Danio rerio] -------------------------------------MARRC------------------ --------LAV------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------LERFFCLV---------------------------------- ------------------------------------------------------------ ----------------------LILSPVALQ----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------QREESGVSLLQLIGDPPPNGVSKVFDQANSPGYVFGPSSN-VGQSAAAHLP NPFYRDFSLIFNIKPTSSKPGVIFSITDPTQNIMYVGVKLSAVERGKQSIIFYYTEPDSQ S-SYEAARFSVSSMLNIWTRFSISVLNEQVSLYFNCDSDPQVVNFERSPD-DMDMDAGAG VFVGHASG-ADPDKFLGVIGDLRVSRDPGAAERHC--------------EE-EEDDY--A TEASGDYGASGDGEQ--PSPVQ------PTPP----SSRPIQRPPVIS---------RDP IQ--RP-PVISREPIQQTV---------------ARGEKGDRGEKGAKGDRGLAGPKGDV GSGSVSGGGSKGDKGVPGEKGMKGTSGFGYP----GSKGDRGPPGPPGPPGPQG------ ------------------PSAEVEVRGDGSVVQKVTGPR---GPPGPQGPPGPPGP---- --------EGEPGDPGEDGKAGQVGPSGFPGNP-----GNPGPKGDKGDRGE---SQPGP RGPPGPPGP------PGPSSGFDRPTFVDMEGS-GF--DMDSVRAVPGLPGPPGPPGP-- -------------PGPPGSASSGS--------GGFGPPGP-------------------- --------PGQNGAPGQPGLS---GVPGADGKPGLPGPKGEKGDAGELGLPGPVGEKGAK GSSGPPGTTGIGGPAGLPGPI---GP---IGLPGPPGPPGPS--FNVGF--------DDM EGS--GVHFSSV---PGVRGPVGIPGPPGVPGPQGQP---------------GFPGLPGE KGSLGAQGNDGLPGADGFPGPQGPKGDKGERGDRGEPGRDGHGHPGQPGPPGPPGQIIYR YSEH------YDEV-GGTGAQGGSGVPGQAGFPGPMGP---------------------- -------------------KGDRGEPGLPGY-DIKGEKGEPGL-----ILGPDGNPLYLG GLTGQKGERGISGPVGPP---------------------------GPAGPPGAKGEFGMP GRPGRPGVNGYKGEKGEPSSGS-GYGY---PGPPGPPGPPGPPGPAVP---LDRFGRYED YAR---------LYPATKGEKGDQGAPGIPGSPGFS-----------------TNFDIYS LKNEMKGE---RGESGLKGEKGEPG--GG-FYDPRFGAVQ---GPP---GNPGPAGPKGD SIRGPPGPQ-------GPPGTPGV-GYDGRPGNPGPPGPPGPPGSP----SL-------- ------PG-PYRP------------------------PLSIPGPP--GPPGPPGIP---G T-------GS-----G---------V-TVLRSHDIMIATARRQTEGTLIYILDRNDLYLR VRDGVRQVMLGDYKPLYG--ELDNEVAAVQPPPVVHYSQD------------HTANNGAE QISPPH---QPIDFP-TREQENRNPNPQPDPRYPD-PRYPPYTDNRYTDPVEPNIRYPVQ PERNPITPARRPIPPVNQP--GGHAHTHTSGPGLHLIALNSPQVGNM-RGIRGADFMCFQ QARAVGMKGTFRAFLSSKLQDLYSIVRRSDRETLPIVNLKDQVLFSSWESLFSD-SESRM KDNAPIYSFDGRDVLRDSAWPEKMIW-HGSDGRGHRQTDN-YCETWRAGDRAVTGLASSL QAGQLLQQTSSSCSSSYIVLCIENSYMTQSKK---------------------------- ----- >NP_445941.2 collagen alpha-1(XVIII) chain precursor [Rattus norvegicus] -------------------------------------MAPR------------------- -------------W---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------HLLDM---LTSLVLL----------------------------------- ------------------------------------------------------------ ---------------------LVARVSWAEP----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ENVAEDVGLLQLLGDPLPQKISQVEDPHVGLAYVFGPYSK-SSQMAQYHFP KLFFRDFSLLFEVRPTTEAAGVLFAITDAAQVVVSLGVKLSEVRDGQQNISLLYTEPGAS Q-TQTGASFRLPAFVGQWTHFALSVDGSSVALYVDCE-EFQRVPFARSPH-GLELERGAG LFVGQAGA-ADPDKFQGMISELRVRKTPRVSPVHCL-------------DE-EDDD---D DRASGDFGSGLEESS-NLHRQET--YLRPGLP----QPPPVTSPPLAG---------GSA TEDSRT-EEKEEEATVDS--------------KGADTLPV-------------------- ---TDSSGVWDGDVQNPGGGLIKG--------GLKGQKGEPGAQGPPGPAGPQG------ ------------------PAGPAVQSPSSQPVPGAQGPP---GPQGPPGKDGIPGR---- --------DGEPGDPGEDGRPGDTGPQGFPGTP-----GDVGPKGEKGDPGI---GPRGP P---GPPGP------PGPSFRQDKLTFIDMEGSGGFSGDLESLRGPRGFPGPPGPPGV-- -------------PGLPGEPGRFGVNSSY-APGPAGLPGV-------------------- --------PGKEGPPGF---PGPPGPPGKEGPPGVAGQKGSVGD------AGSPGPKGSK GDLGPIGMPGKSGLPGLPGPV---GP---PGPPGPPGPPGPG--FAAGF--------DDM EGS--GTPLWSTA-----RSSDGLQ---------GDPGV------------TGPPGAKGE VGADGVQGIPGLPGREGVAGPPGPKGEKGTQGEKGNPGKDGVGRPGLPGPPGPPGPVIYV SNED------RAVV-STPGPE---GKPGYAGFPGPAGP---------------------- -------------------KGDLGSKGEQGLPGPKGEKGEPGS-----IFSPDGTALG-- --QAQKGAKGEPGFRGPP---------------------------GPYGRPGYKGEIGFP GRPGRPGTNGLKGEKGEPGEASLGFSMRGLPGPPGPPGPPGPPGVPV----YDS-NAFVE SGRPGLPGQ--QGVQGPPGPKGDKGEVGPPGPPGQF-----------------P-IDLFH LEAEMKGDKGDRGDAGRKGERGEPGAPGGGFFSSSV---PGPPGPP---GYPGIPGPKGE SIRGPPGPP-------GPQGPPGI-GYEGRQ---GPPGPPGPPGPP----SF-------- ------PG-PHRQ------------------------TVSVPGPP--GPPGPPGPP---G A-------MGAS--AG--------QV-RIWATYQTMLDKIREVPEGWLIFVAEREELYVR VRNGFRKVLLEARTALPH--GTDNEVAALQPPLVQLHEGS------------SYTRREHS YPTA-----RPWRAD---------DILANPPRLPD-RQPYPGVPHH--HHHHHH------ --HHSSHEHRPPAHPSPSP----AHTHQDFHPVLHLVALNTPLSGGM-RGIRGADFQCFQ QARAVGLSGTFRAFLSSRLQDLYSIVRRADRSSVPIVNLKDEVLSPSWDTLFSG-SQGQL HSGARIFSFDGRDVLRHPAWPQKSVW-HGSDPSGRRLMES-YCETWRTEATGVTGQASSL LSGRLLEQKAESCHNSYIVLCIENSFMTSFSK---------------------------- ----- >XP_025007836.2 collagen alpha-1(XVIII) chain isoform X1 [Gallus gallus] -------------------------------------MR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----ALQAPR------------------------------------------------- ------------------------------------------------------------ ----------------------WGQAP---TSAPDPLCLR-------------------- ------------SQGARFPLPMALLH-LGLWLLLASCCFSSSDAQL-------------- ----LDWIWGRPKTT---GTPTAPSTAETLPT---------------------------- ------------------------------------------------------------ --------------------------------------------LSTPLSSAAAGDVATT QRRWEPEPSMAVPTGEESTESTDGTEQGDRSTAG-------ITLPTGTAWTATPPRSTSP THSPTET--------------PLPLGTGNPNTTELPQQQEGAGGSPQRPAA--------- ------ARPENLSTEVSLLELIGDPPPEEILKIYGPDNNPGYVFGPSAN-TGQVARYHLP SPFYRDFSLLFHIQPTTPRAGMLFAITDSTQSIIYVGVKLSDLQMGKQQIIFYYTEPGSQ S-SYAAATFTVPTLLNQWTRFAISVEEDEVILYLDCE-EHERVRFERSPD-EMELEEGSG LFVAQAGG-ADPDKYQGVIADLRLRGDPRAAEHQC--------------EE-EEDD---A E-ASGDFGSGAEDRH-HPSGKDKGI---PGLL----DAVPVTSPPVVEGSGTRS--SAGS PQQAER-TRVEERLQVST-----------GG-TGPKGEKGEKGERGPKGDSGTSG----- ---ILGTGATKGEKGEKGELGIKGSAGFGYP-GSKGQKGEPGEPGPPGP----------- ----------------------LSRHTDSMSLEQVTGPP---GPTGPPGKDGAPGR---- --------DGEPGDPGEDGKPGEMGPQGFPGTP-----GESGQKGEKGDPGV---GPRGP PGPPGPPGP------PGRSSKQDGLTFIDMEGS-GFGGDLETLRGPRGPPGPPGPPGV-- -------------PGLPGEPGRFGMNSTD-LPGP---PGL-------------------- --------PGRDGTPGAPGPEGPLGPPGKDGMPGPPGPKGERGDVGDLGLPGAPGPKGSK GEAGPAGPPGETGLAGLPGPV---GPRGPPGPPGPPGPPGPG--YEAGF--------GDM EGS--GLPLATGS--PGPRGPSGPQGVPGLPGIKGEVGS------------LGQPGPPGP KGDAGVPGVDGRPGLEGFPGPQGPKGNRGSPGEKGERGQDGVGLPGPPGPPGPPGQVIYM SSED------RPLV-ALPGPE---GRSGHAGFPGPVGP---------------------- -------------------KGDPGSPGIQGAPGIKGEKGEPGV-----IISPDGTIVA-- --ANVKGQKGEPGLPGPMG------------------------PSGPHGRAGMKGEIGFP GRPGRPGMNGLKGEKGDPVDISSVLSLRGPPGPPGPPGPPGPPGSVV----YDSNNGFSD ASR---PAF--PGFHQFPGQKGEKGDVGAPGPPGQF-----------------P-YDLSR FSASLRGD---KGEAGPKGEKGEPG--SSTLYGPSV---TGPPGPQ---GYPGPPGPKGD SIVGPPGPP-------GPQGPPGI-GYEGRQ---GPPGPPGPPGPP----SF-------- ------PG-PHRQ------------------------AISIPGPP--GPPGPPGPP---G T-------SGTS--LG---------L-RTMPTYQAMLSAAHELPEGGLIFLADRQELYIR LRGGFRRVLLEEHTLVPS-SALDNEVYDKLPSIH--YGGA------QQ--PVHPLRNHNP PPTA-----RPWRGD---------EVVANQHHLPQPPLL----------QQHEL------ --LNSYYIHRWP-DPAPVA----AHVHQDFQPALHLVALNTPLSGGM-RGIRGADFQCFQ QARQVGLAGTFRAFLSSRLQDLYSIVRRADRTAVPIVNLRDEVLFSNWEALFTG-SEAPL RAGARILSFDGRDILQDSAWPQKSIW-HGSDAKGRRLPES-YCEAWRTDERGTSGQASSL SSGKLLEQSASSCQHAFVVLCIENSFMTAAKK---------------------------- ----- >XP_009439942.2 collagen alpha-1(XVIII) chain isoform X1 [Pan troglodytes] -------------------------------------MAPYPCG----CHILLLLFCCLA AARADLLNLNWL-W----------------------FSNEDTSHAATTIPEPQG-PLPVQ PT---ADTT----------THVTPRNGSTEP----------------------------- ATAPGSPEPPSELLE--------------------------------------------- --------------------DGQDTPT--------SAESPD------APEENIAGVG--- ---------AEILNVAKGIRSFVQLWN---DTVPTESLARAETLVLETP----------- ------------VGPLALAGPSSTPQENGTTLWPSRGIPSSLGAHT---TEAGTLPAPTP SPPSLGRPWAPLT---------GPSVPPPSSGRASLSSLLGGAPPWGSLQDP------DS QGLSPAAAAPSQQLQRPDVRLRTPLLHPLVTGSLGKHAAPSAFSSGLPGALSQVAVTTLI RDSGAWVSHVANSVGPGLANNSALLGAD-------PE-APAGRCLPLPPSLPVCGRLGIS HFWL---PNHLHHESGEQVRAGARAWGGLLRTHCHPFLAWFFCLLLAPPCGSVPPPAPPP CRQFCEALQDACWSRLGGGRLPVACAS-------LPTQEDGY-CVFIGPAA--------- ---------ERVSEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDAN-SGQVARYHFP SLFFRDFSLLFHIRPATEGPGVLFAITDSAQAVVLLGVKLSGVQDGHQDISLLYTEPGAG Q-THTAASFRLPAFVGQWTHLALSVAGGFVALYVDCE-EFQRMPLARSSQ-GLELEPGAG LFVAQAGG-ADPDKFQGVIAELKVRRDPQVSPMHCL-------------DE-EGDD---S DGASGDSGSGLGDTR-ELLREETGVALKPRLP----TPPPVTTPPLAG---------GSS TEDSRS-EEIEEQTTVAS--------------LGAQTLPG-------------------- ---SDSVSTWDGSVRTPGGRVKEG--------GLKGQKGEPGVPGPPGRAGPPGSPCLPG PPGLPCPV---------SPLGPA--GPALQPVPGPQ------GPPGPPGRDGTPGR---- --------DGEPGDPGEDGKPGDTGPQGFPGTP-----GDVGPKGDKGDPGV---GERGP PGPQGPPGP------PGPSFRHDKLTFIDMEGS-GFGGDLEALRGPRGFPGPPGPPGV-- -------------PGLPGEPGRFGVNSSD-VPGPAGLPGV-------------------- --------PGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGE------AGAPGHKGSK GDPGPAGARGESGLAGAPGPA---GP---PGPPGPPGPPGPG--LPAGF--------DDM EGS--GGPFWSTA-----RSAAGPQGPPGLPGLKGDPGV------------PGLPGAKGE VGADGVPGFPGLPGREGIAGPQGPKGDRGSQGEKGDPGKDGVGQPGLPGPPGPPGPVVYV SEQD------GSVL-SVPGPE---GRPGFAGFPGPAGP---------------------- -------------------KGNLGSKGEQGSPGPKGEKGEPGS-----IFSPDGGALG-- --PAQKGAKGEPGFRGPP---------------------------GPYGRPGYKGEIGFP GRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPV----YDS-NVFAE SSRPGPPGL--PGNQGPPGPKGAKGEVGPPGPPGQF-----------------P-FDFLQ LEAEMKGEKGDRGDAGQKGERGEPG--GGGFFSSSL---PGPPGPPGPRGYPGIPGPKGE SIRGQPGPP-------GPQGPPGI-GYEGRQGPPGPPGPPGPPGPP----SF-------- ------PG-PHRQ------------------------TISVPGPP--GPPGPPGPP---G T-------MGAS--SG---------V-RLWATRQAMLGQVHEVPEGWLIFVAEQEELYVR VRNGFRKVQLEARTPLPR--GTDNEVAALQPPVVQLHDSN------------PYPRREHP HPTA-----RPWRAD---------DILASPPRLPE-PQPYPGAP---------------- --HHSSYVHLRPARPTSPP----AHTHRDFQPVLHLVALNSPLSGSM-RGIRGADFQCFQ QARAVGLAGTFRAFLSSRLQDLYSIVRRADRTAVPIVNLKDELLFPSWEALFSG-SEGPL KPGARIFSFDGKDVLRHPTWPQKSVW-HGSDPNGRRLTES-YCETWRTEAPSATGQASSL LGGRLLGQSAVSCHHAYIVLCIENSFMTASK----------------------------- ----- >XP_024830782.1 collagen alpha-1(XVIII) chain isoform X1 [Bos taurus] -------------------------------------MAPDPSS-GRGHHGLLLLACCLS AAQADL--FSWI-W----------------------SGNSAWPIAAPA-SKPPD-SSPVW PT---EDTT----------THVAPRDAPTDW----------------------------- WKVSASPTAPLGRPE--------------------------------------------- --------------------VGQGQTPTGPTA---STVSLD------PKEENIAGVG--- ---------AKILNVAQGIRSFVQLWDNAKDTTPAESSAGAET----------------- ------PPPTDTMDDLSTPGPSITPQDSGTTLQLSTTALSSPDTQR---TEAGTLPMPTQ PPPSPGRPW------------FRESLVSPTPGRSSLSSVPAPAPPRGSQLPLGRPLQLDG EGLLLAAARPGQQ--HADDRRPMPPLPPLVTGSLGKHTALWALSSDPPAKLSHVAVSALT VDSGAWAPHVANSAGPGLANKSTLLGAAELAATEQPVPTTAGRCLPLLPSLALCGHLGIR RSWW---PNHLHHTSREEVQAAVPAWGALLRTHCHRFLAWFFCLLLAPRCGPGLPPGLPP CRQFCEALEDACWSHLDGRGLPLPCAS-------LPAREDGH-CVFIGPPA--------- ---------DEEVVEVGLQQLLGEPPPWQVAMVHDPDVGSAYEFGEDGSGGGQAARRLLP GTFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTAARGGRQHMQLLYTEPGAT H-TRTAASFELPALDGRWTRLALSVDGAYARLFVDCK-EVQGQPLAHSLH-DLQLEPDAR LFVAQAGG-ADPEKFQGLISELRLRRDPQVSPRQCQ-------------DEDEDDD---D DGASGDLGSGLVETQ-EHLREELGAPLGPRLP----EAPPVTSPPLAG---------VGN EEDLRT-EEVEESTTASS--------------LGAQTLPS-------------------- ---LGTVGTWDESVWSPGSSVKER--------GLKGQKGEPGAQGPPGPIGPQG------ ------------------PAGPAIDSHEAQPVSGPQGPP---GPPGPPGKDGTPGR---- --------DGEPGDPGEDGKPGDTGPQGFPGTP-----GDVGPKGEKGDPGV---GPRGP PGPQGPPGP------PGPSFKPDRLTFIDMEGS-GFGGDLESLRGPRGFPGPPGPPGV-- -------------PGLPGEPGRFGMNSSD-VPGPAGLPGV-------------------- --------PGRDGPPGRPGPPGPPGTPGKDGQPGLTGQKGSLGE------AGAPGPKGSK GDLGPVGAPGEHGLAGAPGPA---GP---PGPPGPPGPPGPG--FAAGF--------DDM EGS--GSPLWSTA-----RGAEGLQGPPGTPGVKGDPGA------------VGPPGSKGE VGADGAPGLPGLPGREGAAGPQGPKGEKGTQGEKGDPGKDGVGQPGLPGPPGPPGPVVYV SEQD------RVLA-SVPGPE---GRAGFAGFPGPAGP---------------------- -------------------KGDLGAKGQQGIPGPKGEKGEPGT-----FFGPDGRALT-- --PAQKGAKGEPGFRGPP---------------------------GPYGRPGHKGEIGFP GRPGRPGMNGLKGEKGEPGDASVGFGMRGPAGPPGPPGPPGPPGTPV----YDS-NAFVD SGRPGPPGL--PGHQGPSGLKGDKGDVGPPGPPGQF-----------------P-FDLLQ LGAEMKGEKGDRGAAGQKGERGEPG--GGGFFGSGV---PGPPGPP---GYPGIPGPKGE SIRGQPGPP-------GPQGPPGI-GYEGPQGPPGPPGPPGPPGPP----SF-------- ------PG-PYRQ------------------------TISVPGPP--GPPGPPGPP---G S-------MGTS--SGGSTGLGFQQV-RVWATYQMLVDQVPQVPEGWLIYVADREELYVR VRNGFRKVLLEAHVPLPH--GTDNEVAVLQPPLVQLHEGN------------PYPRREVP HPTA-----RSWRAD---------DILASPPRLPH-PQPYPGAP---------------- --HHGAYAHLRPVPPTASP----SHTHHDFQPVLHLVALNSPQSGGL-RGIRGADFQCFQ QARAAGLAGTFRAFLSSRLQDLYSIVRRADRATLPVVNLRDEVLFPSWEALFSG-SEGQL KPGARIFSFDGRDVLQHPTWPQKSVW-HGSDPSGRRLTES-YCETWRTDSRAATGQASSL LAGRLLEQKAAGCHNAFIVLCIENSFMTSSSK---------------------------- ----- >XP_010711461.1 collagen alpha-1(XVIII) chain isoform X1 [Meleagris gallopavo] -------------------------------------M---------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------PRAADH--------------------------------AGT---------- ------------------------------------------------------------ --------------------RGWGPWA---IPRPSPATPS-------------------- ------------AATPGDADPKCSTNGEGLALLGVSGNQSPSVPKLRAVSGVDSPPAG-- -PPEFDLLTSTLQVV---GAGLAPSFPRLLPA---------------------------- ------------------------------------------------------------ ----------------------------------------GGHCLPLPAHLPFCSVLGTN HVRL---PNYLSHSSEVEIRAALHEWEGLLESRCHRYLEWFLCLLLVPGCSASVPVTPPP CQGFCEAVRDLCWMHSAGGRLPLPCDS-------LPKEDEGYSCVFVNVSS--------- ---------ENLSSEVSLLELIGDPPPEGIVKIYGHENRPGYVFGPSAN-TGQVARYHLP SPFYRDFSLLFHIQPTTPRAGVLFAITDSTQSIIYVGVKLSDLQMGKQQIIFYYTEPGSQ S-SYAAATFTVPTLLNQWANFAISVEEDEVILYLDCE-EHERVRFERSPD-EMELEEGAG LFVGQAGG-ADPDKYQGVIADLRLRGDPRAAEYHC--------------EE--EDD---T E-ASGDFGSGAEDRH-RPLGKDKGI---PGLL----DAVPVTSPPVVEGSGTRS--SVGS PQQAER-TRVEERLQVST-----------GG-TGPKGEKGEKGERGLKGDSGTIG----- ---ILGPGTAKGEKGEKGELGIKGSAGFGYP-GSKGQKGEPGEPGPPGP----------- ----------------------LSRHTDGMSLEQVTGPP---GPTGPPGKDGAPGR---- --------DGEPGDPGEDGKPGEMGPPGFPGTP-----GESGQKGEKGDPGV---GPRGP PGPPGPPGP------PGPSSKQDRLTFIDMEGS-GFGGDLETLRGPRGPPGPPGPPGV-- -------------PGLPGEPGRFGMNSTD-LPGQ---PGL-------------------- --------SGRDGTPGPPGPEGPLGPPGKDGMPGLPGPKGERGDVGDLGLPGAPGPKGSK GEAGPAGPPGETGLAGLPGPV---GPRGQPGPPGPPGPPGPG--YEAGF--------GDM EGS--GLPLATGS--PGPRGPSGPQGVPGLPGIKGEVGS------------LGQPGLPGP KGDAGVPGVDGRPGLEGFPGPQGPKGNRGSPGEKGERGQDGVGLPGPPGPPGPPGQVIYI SSED------RPLA-ALPGPE---GRPGLAGFPGPVGP---------------------- -------------------KGDPGSPGIQGAPGMKGEKGEPGV-----IISPDGTIVA-- --ANMKGQKGEPGLQGPMG------------------------PSGPHGRAGMKGEIGFP GRPGRPGMNGLKGEKGDPVDISGMLSLRGPPGPPGPPGPPGPPSSVV----YDSNNGFSD ASR---PAF--PGFHQFTGQKGEKGDVGAPGPPGQF-----------------L-YDLSR FSANLRGD---KGEAGPKGEKGEPG--GSTLYGPGV---TGPPGPQ---GYPGPPGPKGD SIVGPPGPP-------GPQGPPGI-GYEGRQ---GPPGPPGPPGPP----SF-------- ------PG-PHRQ------------------------AISIPGPP--GPPGPPGPP---G T-------SGTS--LG---------L-RAMPTYQAMLSAAHELPEGGLIFVTDRQELYVR LRGGFRRVLLEEHTLIPS-SALDNEVYDKLPSIH--YGGA------QQ--PVHPLRNHSP PPTA-----RPWRGD---------EVVANQHRLPQPPLL----------QQHEL------ --LNSYYIHRWP-DPASVA----AHVHRDFQPALHLVALNTPLSGGM-RGIRGADFQCFQ QARQVGLAGTFRAFLSSRLQDLYSIVRRADRTSVPIVNLRDEVLFSNWEALFTG-SEAPL RAGARILSFDGRDILQDSAWPRKSIW-HGSDVKGRRLPES-YCEAWRTDERGTSGQASSL SSGKLLEQSASSCQHAFVVLCIENSFMTAAKK---------------------------- ----- >XP_020927188.1 collagen alpha-1(XVIII) chain isoform X1 [Sus scrofa] -------------------------------------MAPDPSGRPGHLGLLLLLACCLA ATWADP--FPWL-W----------------------FSEATMPKATPA-SVPQATPAPVP PG-----SS----------PEQRPETPPRTWTPGMAPPTRGKPRPALSLVWRGWRGAR-- ARAPLSPRPPREP----------------------------------------------- --------------------GPQGGEH--------RGCGSQ------DPER---GSG--- ---------HPALHPAVG-----------RHHAPRE-LRRRGDASPPTP----------- ------------TDPLTTPGPSSTLWESGTTLWLSSGAPSSPDTQR---TEAGTQPLPTQ PPPSPGGPLAPFR---------APSVPPPAPGRASLSPAPGGAPPWGSQLSPGWSQELDG KGLLPVAARPGQQHRHPDVRR--PPLLPLVTGSPGAH-GPSALSSGAPATLSYVALAALI GDGGAWLPHVANSSGPGLAHTSAQLGA-------------TGRCLPLPPSLAICSRLGIG RVWL---PNHLHHGSGEEVQAAARAWGALLQTRCHRFLAWFFCLLLAPPCGLG-PAAPPP CRQFCETLEDACWSHLDGGGLPVPCAS-------LPAREDGH-CVFIGPAA--------- ---------EGEAVEVGLQQMLGEPLPRQVALVHDPDVGPAYEFDGISG-VGQAALSLVP RTFFHDFSLLMRVRPASAGAGVLFAVTDAAQAVVLVGVKLAAARGGQQQVQLLYTEPGAT R-TRTAASFTLPALHGRWTHLALSVDGAHVALFVDCE-EVQLEPLSRSLR-ALQLEPDAR LFVAQAGR-ADPDKFQGMISELRVRGDPQVSPLQCRYG-----------DEDEDDS---D NEASGDLGSGLAEEAGERLGAPSGAPLRPRLP----EAPPVTSPPLAG---------AGD EEDSRT-EEVEEATTVPS--------------PGAQTLPG-------------------- ---SGAVTTWDGSSWSPGDSLEER--------GLKGQE-EPGAQGLPGQASPQG------ ------------------PTGPVMRSPEAQPVPGPQGPP---GPPGPPGKDGAPGR---- --------DGEPGDPGEDGKPGDTGPQGFPGTP-----GDVGPKGEKGDPGV---GPRGP PGPQGPPGP------PGPSFRHDKLTFIDMEGS-GFGGDLESLRGPRGFPGPPGPPGV-- -------------PGLPGEPGRFGMNSSD-VPGPAGLPGV-------------------- --------PGRDGAPGPPGPPGPPGFPGRDGQAGQTGQKGSVGE------VGAPGPKGSK GDPGPVGAPGNPGLAGVPGPA---GP---PGPPGPPGPPGPG--LAAGF--------DDM EGS--GGPFWWAA-----QGADRPQAPPGPPGVKGDPGA------------VGPAGTKGE VGADGAPGLPGLPGREGAAGPQGPKGEKGTRGDKGDPGKDGVGQPGLPGPPGPPGPVVYV S--D------RAVA-SVPGPE---GRTGFAGFPGPAGP---------------------- -------------------KGDLGSKGQPGLPGPKGEKGEPGT-----VFSPDGRPLT-- --PAQKGAKGEPGFRGPP---------------------------GPYGRPGHKGEIGFP GRPGRPGMNGLKGEKGEPGDASVGFSLRGPPGPPGPPGPPGPAGTPV----YDS-NAFVE SGRPGPPGL--PGYQGPPGPKGDKGEMGPPGPPGQF-----------------P-FDLLH MEAELKGEKGDRGEAGQKGERGEPG--GGGFFGSSV---PGPPGPP---GYPGIPGPKGE SIRGQPGPP-------GPQGPPGI-GYEGRQGPPGPPGPPGPPGPP----SF-------- ------PG-PYRQ------------------------TISVPGPP--GPPGPPGPP---G S-------MGGS--SG--------QV-RVWATYQTMLDKVPEVPEGWLMFVAEREELYVR VRNGFRKVLLEARTPLPRGTGTDNEVAALQPPVVQLHEGN------------PYPRREPP QPTA-----RAWRGD---------DIRASPPRLPV-AQPYPGAP---------------- --HHGAYVHPRPVHPTGSP----AHTHHDFQPVLHLVALNSPQSGGL-RGIRGADFQCFQ QARAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLRDEVLFPSWEALFSG-SEGQL KPGARIFSFDGRDVLQHPAWPQKSVW-HGSDPSGRRLTES-YCETWRTEARTATGQASSL LAGRLLEQKAAGCHHAFIVLCIENSFMTSASK---------------------------- ----- >XP_038299617.1 collagen alpha-1(XVIII) chain isoform X1 [Canis lupus familiaris] -------------------------------------MARHPGR---CLLLLLLLTCCPA AAQVDLLSLNWL-W----------------------STRTAGPTAEPV-SEAPG-SPHVQ PR---DETG----------TPVTPQPGPTEQ----------------------------- GNAPASPEPPLRGLE--------------------------------------------- --------------------TDEHAASAAPSA---PPAGPDPK---EEKEENIAGVG--- ---------AKILNVAQGIRSFVQLWD---DTTRPESSSTAGTPAPVTP----------- ------------TSPLALPGPSRPPPENGTALW-----LGSTDAPR---VEASTLPAPTR LPPSLDRPRAALR---------EPSGPPPSP----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ESRGSEVGLLQLLGEPPPQQVTQVDDPDVGPAFVFGPDAN-SGQVARYHVP SPFFRDFSLLMHVRPATEGPGVLFAITDAAQAVVSVGVKLSGVRDGQQHVQLLYTEPGAA R-TRTAASFRLPAFTGQWTRLALSVDGATVALFVDCE-LFQRVPLERSPG-GLQLEPGAG LFVAQAGG-ADPDKFQGMIAELRVRGDPHVSPLHCL-------------EE-DDDD---S GGVSGDFGSGLEDD-----REPSGLLPKAELP----EAPPVTSPPLTG---------GRD VEDSRM-EEIEEEATASP--------------LGARTLPG-------------------- ---SATVTA--ESAQRLGGSLQE------------------------------A------ ------------------PTGPAAHNPEAWPGPGPQGPP---GPPGPPGKDGTPGR---- --------DGEPGDPGEDGRPGDPGPQGFPGTP-----GDVGPKGEKGDPGV---GPRGP PGPQGPPGP------PGPSFRHDKLTFIDMEGS-GFGGDLESLRGPRGFPGPPGPPGV-- -------------PGLPGEPGRFGMNSSD-VPGPAGLPGV-------------------- --------PGRDGPPGLPGAPGPPGPPGKEGGPGKPGPKGSPGD------AGAPGPKGSK GDPGPIGVPGESGLAGPPGPA---GP---PGPPGPPGPPGPG--LAAGF--------VDM EGS--GEPFWSTA-----HGASGPQGPPGLPGVKGDPGI------------VGPPGAKGE VGADGPPGFPGLPGREGTAGAQGPKGEKGTQGEKGEPGRDGVGQPGLPGPPGPPGPVVYV SEQE------RAAT-GVPGPE---GRPGHAGFPGPAGP---------------------- -------------------KGDLGSKGQRGPPGPKGEKGEPGP-----AFSPDGSMLA-- --PAQKGAKGEPGFRGPP---------------------------GPYGRPGHKGEIGFP GRPGRPGMNGLKGEKGEPGQASAGFGMTGPPGPPGPPGPPGPPGTPV----YDS-NAFME PGHPGPPGL--PGHQGPSGPKGDKGDVGPPGPPGQF-----------------P-FDLLQ LGAEMKGEKGDRGDAGQKGERGEPG--GGGFFGSSV---PGPPGPP---GYPGIPGPKGE SVQGHPGPP-------GPQGPPGI-GHEGRRGPPGPPGPPGPPGPP----SF-------- ------PG-PYRQ------------------------TISVPGPP--GPPGPPGPP---G T-------MGTS--SG--------QV-RIWATYQTMLDKVPDVPEGWLMFVAEREELYVR VRNGFRKVLLEARVPLPR--GTDNEVAALQPPVVQLHEGN------------PYPRREPT HATA-----RPWRAD---------DILASPPRLLD-PQPYPGAP---------------- --HHGSYVHFQPARPTGGPVHTHTHTHQDFQPVLHLVALNSPQPGGM-RGIRGADFQCFQ QARAAGLAGTFRAFLSSRLQDLYSIVRRADRTGVPVVNLRDEVLFPSWEALFSG-SEGQL KPGARIFSFDGRDVLQHPAWPRKSVW-HGSDPSGRRLTDS-YCETWRTEAPAATGQASSL LAGRLLEQEAASCRHAFVVLCIENSVMTSFSK---------------------------- ----- >XP_034803833.1 collagen alpha-1(XVIII) chain isoform X1 [Pan paniscus] -------------------------------------MAPYPCG----CHILLLLFCCLA AARADLLNLNWL-W----------------------FSNEDTSHTATTIPEPQG-PLPVQ PT---ADTT----------THVTPRNGSTEP----------------------------- ATAPGSPEPPSELLE--------------------------------------------- --------------------DGQDTPT--------SAESPD------APEENIAGVG--- ---------AEILNVAKGIRSFVQLWN---DTVPTESLARAETLVLETP----------- ------------VGPLALAGPSSTPQENGTTLWPSRGIPSSLGAHT---TEAGTLPAPTP SPPSLGRPWAPLT---------GPSVPPPSSGRASLSSLLGGAPPWGSLQDP------DS QGLSPAAAAPSQQLQRPDVRLRTPLLHPLVTGSLGKHAAPSAFSSGLPGALSQVAVTTLI RDSGAWVSHVANSVGPGLANNSALLGAD-------PE-APAGRCLPLPPSLPVCGRLGIS HFWL---PNHLHHESGEQVRAGARAWGGLLRTHCHPFLAWFFCLLLAPPCGSVPPPAPPP CRQFCEALQDACWSRLGGGQLPVACAS-------LPTQEDGY-CVFIGPAA--------- ---------ERVSEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDAN-SGQVARYHFP SLFFRDFSLLFHIRPATEGPGVLFAITDSAQAVVLLGVKLSGVQDGHQDISLLYTEPGAG Q-THTAASFRLPAFVGQWTHLALSVAGGFVALYVDCE-EFQRMPLARSSR-GLELEPGAG LFVAQAGG-ADPDKFQGVIAELKVRRDPQVSPMHCL-------------DE-EGDD---S DGASGDSGSGLGDAR-ELLREETGAALKPRLP----TPPPVTTPPLAG---------GSS TEDSRS-EEIEEQTTVAS--------------LGAQTLPG-------------------- ---SDSVSTWDGSVRTPGGRVKEG--------GLKGQKGEPGVPGPPGQAGPPGSPCLPG PPGLPCPV---------SPLGPA--GPALQPVPGPQ------GPPGPPGRDGTPGR---- --------DGEPGDPGEDGKPGDTGPQGFPGTP-----GDVGPKGDKGDPGI---GERGP PGPQGPPGP------PGPSFRHDKLTFIDMEGS-GFGGDLEALRGPRGFPGPPGPPGV-- -------------PGLPGEPGRFGVNSSD-VPGPAGLPGV-------------------- --------PGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGE------AGAPGHKGSK GDPGPAGARGESGLAGAPGPA---GP---PGPPGPPGPPGPG--LPAGF--------DDM EGS--GGPFWSTA-----RSAAGPQGPPGLPGLKGDPGV------------PGLPGAKGE VGADGVPGFPGLPGREGIAGPQGPKGDRGSQGEKGDPGKDGVGQPGLPGPPGPPGPVVYV SEQD------GSVL-SVPGPE---GRPGFAGFPGPAGP---------------------- -------------------KGNLGSKGERGSPGPKGEKGEPGS-----IFSPDGSALG-- --PAQKGAKGEPGFRGPP---------------------------GPYGRPGYKGEIGFP GRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPV----YDS-NVFAE SSRPGPPGL--PGNQGPPGPKGAKGEVGPPGPPGQF-----------------P-FDFLQ LEAEMKGEKGDRGDAGQKGERGEPG--GGGFFSSSL---PGPPGPPGPRGYPGIPGPKGE SIRGQPGPP-------GPQGPPGI-GYEGRQGPPGPPGPPGPPGPP----SF-------- ------PG-PHRQ------------------------TISVPGPP--GPPGPPGPPGTTG T-------MGAS--SG---------V-RLWATRQAMLGQVHEVPEGWLIFVAEQEELYVR VRNGFRKVQLEARTPLPR--GTDNEVAALQPPVVQLHDSN------------PYPRREHP HPTA-----RPWRAD---------DILASPPRLPE-PQPYPGAP---------------- --HHSSYVHLRPARPTSPP----AHTHRDFQPVLHLVALNSPLSGSM-RGIRGADFQCFQ QARAVGLAGTFRAFLSSRLQDLYSIVRRADRTAVPIVNLKDELLFPSWEALFSG-SEGPL KPGARIFSFDGKDVLRHPTWPQKSVW-HGSDPNGRRLTES-YCETWRTEAPSATGQASSL LGGRLLGQSAVSCHHAYIVLCIENSFMTASK----------------------------- ----- >XP_023094382.1 collagen alpha-1(XVIII) chain isoform X1 [Felis catus] -------------------------------------MARDPGGRLGLLLLLLLLTYGLA AAQVDL--LNWL-W----------------------APRTAGPTVEPA-SAPPR-SPHVQ PT---EETA----------AHVAPRDDPTEQ----------------------------- GRAPASPEPPPGRLE--------------------------------------------- --------------------TGRDQASAVPTA---STAGPD------TKEENIAGVG--- ---------AKILNVAQGIRSFVQLWD---GTTPSQSSTGAETPAPGTP----------- ------------TAPLTLPGPSGAPPEDGTTLWLSSRALTSPDTQR---TEAGTLPVPTQ LPPSPGRPRAPLR---------EPSVPPSSPGRASLSSAPGGAPPRGTQPSPRRPHDLDG GGPSPVAARARRQRRLADSRRPAPHLLPLVTGLPGAHAAPLALSSDLPALVSPIPLPAVT GDKGAWAPHVANSVGPGLANNSALPGADLPTPTRQPA-RPAGRCLPLPPSLPVCGHLGIG RSWL---PNHLRHASSEEVRAAARAWGALLRTHCHRFLAWFFCLLLAPPCGAGPLPAPPP CRQFCEALEDACWSHLDGGGLPVTCAS-------LPAQEDGV-CVFIGPGA--------- ---------ESLGTEVGLLQLLGEPPPQQVAQVDDPDVGPAFVFGPDAN-SGQVARYHFP SPFFRDFSLLFHVRPATEGAGVLFAITDAAQAVVSVGVKLSAVRDGQQHIQLLYTEPGAT R-TRTAASFRLPAFTGQWTRFALSVDGATVALFVDCE-LFQRVPLVRSPR-ALELEPGAG LFVAQAGG-ADPSKFQGRIAELRVRGDPRVSPLHCL-------------EE-DDED---S GGVSGDFGSGLEENR-ELLREQSGLSPKPSLP----EAPPVTSPPLAG---------GRN VEDART-EEIEEETTMSS--------------LGAWTLPG-------------------- ---SDTVTAW--SVRSPGGGPEE------------------------------G------ ------------------PAGSAVHSPDAQPVPGPQGPP---GPPGPPGKDGAPGK---- --------DGEPGDPGEDGKPGDPGPQGFPGTP-----GDMGPKGEKGDPGV---GPRGP PGPQGPPGP------PGPSFRHDRLTFIDMEGS-GFGGDLESLRGPRGFPGPPGPPGV-- -------------PGLPGEPGRFGMNSSD-VPGPAGLPGV-------------------- --------PGRDGAPGLPGAPGPPGPPGRDGGPGKTGQKGSPGE------AGAPGPKGSK GDPGPTGAPGETGLAGAPGPA---GP---PGPPGPPGPPGPG--LAAGF--------EDM DGS--GGPFWATA-----HGASGPQGPPGLPGVKGDPGI------------AGPPGAKGE VGADGPPGFPGLPGREGTAGAQGPKGEKGTQGEKGDPGRDGVGQPGLPGPPGPPGPVVYV SEQD------RAVA-GVPGPE---GRPGYAGFPGPAGP---------------------- -------------------KGDLGSKGQRGPPGPKGEKGEPGP-----VFSPDGGTLG-- --PAQKGAKGEPGFRGPP---------------------------GPYGRPGHKGEIGFP GRPGRPGMNGLKGEKGEPGHASVGFGVRGPPGPPGPPGPPGPPGTPV----YDS-NAFME SGRPGPPGL--PGYQGPPGPKGDKGEVGPPGPPGQF-----------------P-LDLLQ LEAEMKGEKGDRGDPGQKGERGEPG--GGGFFGSSV---PGPPGPP---GYPGIPGPKGE SIRGQPGPP-------GPQGPPGI-GHEGRQGPPGPPGPPGPPGPP----SF-------- ------PG-PYRQ------------------------TISVPGPP--GPPGPPGPP---G T-------MGTS--SG--------QV-RIWATYQTMLDKVPEVPEGWLIFVAETEELYVR VRNGFRKVLLEARTPLPR--GTDNEVAALQPPLVQLHEGH------------PYPRRELT HSTA-----RPWRAD---------DILAGPPRLPD-PRPYPGAP---------------- --QNGPYLHVQPARPTGGP--ARTHAHQDFQPVLHLVALNSPQPGGM-RGIRGADFQCFQ QARAVGLAGTFRAFLSSRLQDLYSIVRRADRTGVPIVNLRDEVLFPSWEALFSGSSEGQL KPGARVFSFDGRDVLQHPAWPQKSVW-HGSDPSGRRLTDS-YCETWRTEDAAAAGQASSL LAGRLLAQKAASCRNAFIVLCIENSFMTSSSK---------------------------- ----- >XP_027816975.1 collagen alpha-1(XVIII) chain isoform X3 [Ovis aries] -------------------------------------MAPDPSS-RCGHHSLLLLACCLS AAQAQL--LSWL-W----------------------SGNSAWPTAAPA-SKTPD-SSPVW PT---EETT----------THVAPRDASTDW----------------------------- WKVPASPTDPLGRPE--------------------------------------------- --------------------AGQGQTPAGPTA---SSSSPD------LKEENIAGVG--- ---------AKILNVAQGIRSFVQLWDDAQDTTPAESSARAGMLAPATPTDPLSTAPAEG STRAETPPPVDTTDTLSTPGPSSTPQDSGTTLQPSTKALSSPDTQM---TEAGALPVPTQ PPPSPGRPW------------FRESLVPPTP----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------DGEVVEVGLQQLLGEPPPWQVAVVHDPAVGPAYEFGEDGSGGGQAARSLLP SAFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTAARGGRQHLQLLYTEPGAT D-TRTAASFELPALDGRWTRLALSVDGAYARLFVDCE-EVQGQPLAHSLH-DLQLEPDAR LFVAQAGG-ADPEKFQGLISELRLRRDPRVSPRQCQ-------------DEDEDDD---D DGASGDLGSGLMETQ-EHPREELGTPLGPRLP----EAPPVTSPPLAG---------VGT EEDLRT-EEVEESTTVSS--------------LGAQTLPS-------------------- ---LGTVGTWDESVWSPGSSVKEQ--------GLKGQKGEPGAQGPPGPIGPQG------ ------------------PAGPAIDSHEAQPVSGPQGPP---GPPGPPGKDGTPGR---- --------DGEPGDPGEDGKPGDTGPQGFPGTP-----GDVGPKGEKGDPGV---GPRGP PGPQGPPGP------PGPSFKPDRLTFIDMEGS-GFGGDLESLRGPRGFPGPPGPPGV-- -------------PGLPGEPGRFGMNSSD-VPGPAGLPGV-------------------- --------PGRDGLPGVPGPPGPPGIPGKDGQPGLTGQKGSLGE------AGAPGPKGSK GDPGPIGAPGEHGLAGAPGPA---GP---PGPPGPPGPPGPG--FAAGF--------DDM EGS--GSPFWSTA-----RGADGLQGPPGTPGVKGDPGA------------VGPPGSKGE VGADGAPGFPGLPGREGAAGPQGPKGEKGTQGEKGDPGKDGVGQPGLPGPPGPPGPVVYV SEQD------RVLA-SVPGPE---GRAGFAGFPGPAGP---------------------- -------------------KGDLGAKGQQGIPGPKGEKGEPGT-----FFGPDGRALT-- --PAQKGAKGEPGFRGPP---------------------------GPYGRPGHKGEIGFP GRPGRPGMNGLKGEKGEPGDASVGFGMRGPPGPPGPPGPPGPPGTPV----YDS-NAFVD SGRPGPPGL--PGHQGPSGPKGDKGDVGPPGPRGQF-----------------P-FDLLQ LGAEMKGQKGERGAAGQKGERGEPG--GGGFFGSGV---PGPPGPP---GYPGIPGPKGE SVRGQPGPP-------GPQGPPGI-GYEGRQGPPGPPGPPGPPGPP----SF-------- ------PG-PYRQ------------------------TISVPGPP--GPPGPPGPP---G S-------MGTS--SG---------V-RVWATYQMLVDQVPQVPEGWLIYVADREELYVR VRNGFRKVLLEAHMPLPH--GTDNEVAVLQPPLVQLHEGN------------PYPRREAP HPTA-----RSWRAD---------DILASPPRLPH-PQPYPGAP---------------- --HHGTYAHLRPVTSTASP----SHTHHDFQPVLHLVALNSPQSGGL-RGIRGADFQCFQ QARAAGLAGTFRAFLSSRLQDLYSIVRRADRGSLPVVNLRDEVLFPSWEALFLG-SQGWL KPSARIFSFDGRDVLQHPAWPQKSVW-HGSDTSGRRLTES-YCETWRTDSRAATGQASSL LSGRLLEQKAAGCHNAFIVLCIENSFMTSSSK---------------------------- ----- >XP_030860999.1 collagen alpha-1(XVIII) chain [Gorilla gorilla gorilla] -------------------------------------MAPYPCG----CHILLLLFCCLA AARANLLNLNWL-W----------------------FNNEDTSHAATTIPEPQG-PLPVQ PT---ADTTPAD-------THVTPQNGSTEP----------------------------- ATAPGSPEPPSELLE--------------------------------------------- --------------------DSQDTPT--------SAESLD------APEENIAGVG--- ---------AEILNVAKGIRSFVQLWN---DTVPTESLARAETLVLETP----------- ------------VGPLALAGPSSTPQENGTTLWPSRGIPSSLGAHT---TKAGTLPAPTP SPPSLGRPWAPLT---------GPSVPPPSSGRASLSSLLGGAPPWGSLQDP------DS QGLSPAAAAPSQQLQRPDVRLRAPLLHPLVTGSLGKHAAPSAFSSGLPGALSQVAVTTLI RDSSAWVSHVANSVRPGLANNSALLGAD-------PE-APAGRCLPLPPSLPVCGRLGIS RFWL---PNHLHHESGEQVRAGARAWGGLLRTHCHPFLAWFFCLLLAPPCGSVPPPAPPP CRQFCEALQDACWSRLGGGRLPVACAS-------LPTQEDGY-CVFIGPAA--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --VGRAG----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------------PGV---GLR-- ---QAPCGK--------------------------------------------------- ---------------------------------------V-------------------- --------SGNDQC---------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------PAVPTPCAPP------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --QGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPV----YDS-NVFAE SSRPGPPGL--PGNQGPPGPKGAKGEVGPPGPPGQF-----------------P-FDFLQ LEAEMKGEKGDRGDAGQKGERGEPG--GGGFFGSSL---PGPPGPPGPRGYPGIPGPKGE SIRGQPGPH-------GPQGPPGI-GYEGRQGPPGPPGPPGPPGPP----SF-------- ------PG-PHRQ------------------------TISVPGPP--GPPGPPGPP---G T-------MGAS--SG---------V-RLWATRQAMLGQVHEVPEGWLLFVAEQEELYVR VRNGFRKVQLEARTPLPR--GTDNEVAALQPPMVQLHDSN------------PYPRREHP HPTA-----RPWRAD---------DILASPPRLPE-PQPYPGAP---------------- --HHSSYVHLRPARPTSPP----AHTHRDFQPVLHLVALNSPLSGSM-RGIRGADFQCFQ QARAVGLAGTFRAFLSSRLQDLYSIVRRADRAALPIVNLKDELLFPSWEALFSG-SEGPL KPGARIFSFDGKDILRHPTWPQKSVW-HGSDPNGRRLTES-YCETWRTEAPSATGQASSL LGGRLLGQSAASCHHAYIVLCIENSFMTASK----------------------------- ----- >XP_013226958.1 LOW QUALITY PROTEIN: collagen alpha-1(XVIII) chain [Columba livia] -------------------------------------MALAPCC----LGFLLLLACCFS SSETQL--LDWI-WSSR-----------------KTTGSTAAPSKGTT--APELLASVAA PT---PNTSTGTRGDQVEGDITTPQHWEQDPG--TVAPMGEGTVAENTEQWDGNATGLVE STAQPSIAPPRSTSPAPGQDAATSS---TEDLQLLGTGTTKDLQLLGTGTAEDPQLLGTG TTDDLQLLGMGTTKDPQFLGTGTTEDPQLRGT--GTTKNPQFLGTGTTEDLQLLGTGTSK DQKLLGTVTPAVMGIPVSLQRPVGPWP---GSAPFPFSPGDDPHEQVVL-------PQNP TAQ---PPQTHHGASPAPPNLQRGTGRWGLVLAGMNGSRSPPLPNRRLTNSVDPPLADNS RPLGFDLLTSAARLYSSSGVGLAAFLPRLISP---------------------------- ------------------------------------------------------------ ----------------------------------------TGHCLPIPTHLPFCSVLGTH HVRL---PNYLRHGSEVEIRAALHDWEGLLESRCHLYVEWFLCLLLLPGCSASVPVTPPP CQGFCEAVRDQCWMHLAGGRLPLPCDA-------LPEEDEGYSCVFINASA--------- ---------ENLSAEVSLLELIGDPPPEEILKIYGPDNNPGYVFGPNAN-TGQVARYHLP SPFYRDFSLLFHIQPTSPRAGVLFAITDSSQSIIYMGVKLSELQAGKQQIIFYYTEPGSP S-SNAAATFTVPTLLNQWTRFAISVEEDEVILYLDCE-EHERTHFERSPD-EMELEDGSG LFVAQAGG-ADPDKYQGVIADLKLRGDPRAAERQC--------------EE-EEDD---T EEVSGDFGSGAEGGH-QPSGKDRGV---PGLV----DAVPVTSPPVAAGGGVRS--GGGS LQQAER-TRAEETLRVSA-----------GG-TGPKGEKGEKGERGLKGDSGTGS----- ---IVGTGSIKGEKGEKGEVGIKGSAGFGYP-GSKGQKGEPGDPGSPRT----------- ----------------------LSRHADGSVVEQITGPP------GPPGKDGAPGR---- --------DGEPGDPGEDGKPGAMGPQGFPGMP-----GEPGLKGEKGDPGV---GPRGP PGPPGPPGP------PGPSSKHDKLTFIDMEGS-GFGGDLESLQGPRGPPGPPGPPGV-- -------------PGLPGEPGRFGMNQTD-LPGP---PGL-------------------- --------PGRDGTPGSPGPAGPQGPSGRDGAPGQPGPKGERGDVGDLGLPGAPGPKGSK GETGPAGAPGETGLAGLPGPM---GPRGPPGPPGPPGPPGPG--YEAGF--------SDM EGS--GLPFAASS--PGQPGPEGPQGVPGLPGMKGEVGS------------PGQPGLPGP KGDAGVPGVDGRPGLEGFPGPQGPKGDRGSPGEKGERGQDGVGLPGPPGPPGPPGQVITV SSED------RSLV-ALPGPE---GRPGHAGFPGPLGP---------------------- -------------------KGDQGPSGPQGPPGLKGEKGEPGV-----IISPDGTVVT-- --AKVKGEKGEPGLRGPVG------------------------PSGPPGRAGMKGEIGFP GRPGRPGMNGLKGEKGDPADVSSVLGLRGPPGPPGPPGPPGPPGSVV----YDSSNAFSD SGRPVLPAF--PGFHQFPGQKGEKGDTGAPGPPGHF-----------------P-YDLSH FGASLRGD---KGDAGPKGEKGEPG--STPLYGPSVSGLPGPPGPQ---GYPGLPGPKGD SIVGPPGPP-------GPQGPPGI-GYEGRQ---GPPGPPGPPGPP----SF-------- ------PG-PHRQ------------------------AISIPGPP--GPPGPPGPP---G T-------SGMS--LG---------VTRPLPTYQAMLSAAHELPEGSLVFLTDRQELYVR LRGGFRRVLLEEHTLIPS-SALVSSLSSIHPSIQPSISNH------SR--PQPSISNHSP PPTA-----RPWRGD---------EVVANQHRLPEQPLLH---------HQHEL------ --LNSYYIHRRP-DPAPVA----AYVHQDFQPALHLVALNTPLSGSM-RGIRGADFQCFQ QARQVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLRDEVLFSNWEALFTG-SGAPL RAGARILSFDGRDVLRDAGWPQKSVW-HGSDAKGRRLPES-YCE----XQIPATGQASSL GSGKLLEQVASSCQHNFIVLCIENSFMTAAKK---------------------------- ----- >XP_017907685.1 PREDICTED: collagen alpha-1(XVIII) chain isoform X1 [Capra hircus] -------------------------------------MAPDPSS-RRGHHSLLLLACCLS AAQAQL--LSWL-W----------------------SGNSAWPTAPPA-SKTSD-SSPVW PT---EETT----------THVAPRDASTDW----------------------------- WKVPASPTDPLGRPE--------------------------------------------- --------------------AGQGQTPAGPTA---SSSSPD------LKEENIAGVG--- ---------AKILNVAQGIRSFVQLWDDAQDTTPAESSARAGMLAPATPTDPLSTALAEG STRAETPPPTDTTDTLSTPGPSSTPQDSGTTLQSSTKALSSPDTQM---TKAGALPVPTQ PPPSPGRPW------------FRESLVTPTP----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------DGEVVEVGLQQLLGEPPPWQVAVVHDPAVGPAYEFGEDGSGGGQAARSLLP STFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTAARGGRQHLQLLYTEPGAT D-TRSAASFQLPALDGRWTRLALSVDGAYARLFVDCK-EVQGQPLAHSLH-DLQLEPDAR LFVAQAGG-ADPEKFQGLISELRLRRDPRVSPRQCQ-------------DEDEDDD---D DGASGDLGSGLMETQ-EHPREELGTPLGPRLP----EAPPVTSPPLAG---------VGT EEDLRT-EEVEESTTASS--------------LGAQTLPS-------------------- ---LGTVGTWDESVWSPGSSVKEQ--------GLKGQKGEPGAQGPPGPIGPQG------ ------------------PAGPAIDSHEAQPVSGPQGPP---GPPGPPGKDGTPGR---- --------DGEPGDPGEDGKPGDTGPQGFPGTP-----GDVGPKGEKGDPGV---GPRGP PGPQGPPGP------PGPSFKPDRLTFIDMEGS-GFGGDLESLRGPRGFPGPPGPPGV-- -------------PGLPGEPGRFGMNSSD-VPGPAGLPGV-------------------- --------PGRDGLPGLPGPPGPPGIPGKDGQPGLTGQKGSLGE------AGAPGPKGSK GDPGPIGAPGEHGLAGAPGPA---GP---PGPPGPPGPPGPG--FAAGF--------DDM EGS--GSPFWSTA-----RGADGLQGPPGTPGVKGDPGA------------VGPPGSKGE VGADGAPGFPGLPGREGAAGPQGPKGEKGTQGEKGDPGKDGVGQPGLPGPPGPPGPVVYV SEQD------RVLA-SVPGPE---GRAGFAGFPGPAGP---------------------- -------------------KGDLGAKGQQGIPGPKGEKGEPGT-----FFSPDGRALT-- --PVQKGAKGEPGFRGPP---------------------------GPYGRPGHKGEIGFP GRPGRPGMNGLKGEKGEPGDASVGFGMRGPPGPPGPPGPPGPPGTPV----YDS-NAFVD SGRPGPPGL--PGHQGPSGPKGDKGDVGPPGPRGQF-----------------P-FDLLQ LGAEMKGQKGERGAAGQKGERGEPG--GGGFFGSGV---PGPPGPP---GYPGIPGPKGE SVRGQPGPP-------GPQGPPGI-GYEGRQGPPGPPGPPGPPGPP----SF-------- ------PG-PYRQ------------------------TISVPGPP--GPPGPPGPP---G S-------MGTS--SGGSTGLGFQQV-RVWATYQMLVDQVPQVPEGWLIYVADREELYVR VRNGFRKVLLEAHTPLPH--GTDNEVAVLQPPVVQLHEGN------------PYPRREAP HPTA-----RSWRAD---------DILASPPRLPH-PQPYPGAP---------------- --HHGAYAHFRPVTSTASP----SHTHHDFQPVLHLVALNSPQSGGL-RGIRGADFQCFQ QARAAGLAGTFRAFLSSRLQDLYSIVRRADRGSLPVVNLRDEVLFPSWEALFLG-SEGWL KPGARIFSFDGRDVLQHPAWPQKSVW-HGSDTSGRRLTES-YCETWRTDSRAATGQASSL LSGRLLEQKAAGCHNAFIVLCIENSFMTSSSK---------------------------- ----- >XP_006022141.1 collagen alpha-1(XVIII) chain isoform X2 [Alligator sinensis] -------------------------------------MAPAKPS----LCLLLLLTCCFS LSEAQL--LSWLGWERP-----------------KQEARTVPPEENST------------ -------TE-----EQTMGSLTSP------------------------------------ --AASTLHAPLQTTA-----------------QQEG------------------------ -----KIRNIF---------TLKRQEPESDVT--VPTAAPS--QTPKDKEENIAGVG--- ---------AEILTVAEGIRSLVQLWDE-KVTKGTEGTEELTT----------------- ------------AAPFTAAHPSLSATSLVTGPAGIENMTADSTGGA-------------- ------------------QSPLETGQPEVVF----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------P---------------------------------------------VPTGPPP ----------VLW-----------------------------------------NRTRVL LQQPASPPPENFSTEVGLLQLIGDPPPEQITKIYGPDNNPGYVFGPDAN-TGQVARYHLP SPFYRDFSLLFHIQPTTNKAGVLFAITDSSQAVIYIGVKLSDAKEGKQHIIFYYTEPGSQ S-SYAAATFTVSSLLNQWTRFAVSVEDEEVVLFLDCE-EYDRIRFERSPD-EMELEDGSG LFVGQAGG-ADPDKYQGVIADLKIKNDPHAAVLQC--------------EE-DEDD---T EEMSGDFGSGVEEKL-HSSGKERGIPTVSGLP----KPPPVTSPPIAGRPVEKV--SGSS QLQTEH-IKAEETPPVST-----------GARVGQKGEKGEKGERGPKGDSRTGG----- ---VPSTGGVKGEKGEKGELGVKGSAGFGYP-GSKGQKGEPGAPGDPGPPGPPG------ ------------------PSGTILQHQDGSVVEHVTGPPGAMGPPGLPGKDGFPGK---- --------DGEPGDPGEDGKPGDTGPQGFPGTP-----GEPGLKGEKGDPGVSVKGSPGP PGPPGPPGI------PGLSSKQDKLTFIDMEGS-GFAGDLESLRGPRGPPGPPGPPGV-- -------------PGLPGEPGRFGMNHTA-IPGP---PGL-------------------- --------PGKDGSPGLQGPPGPPGPPGREGLPGQPGFRGEKGDSGDLGLPGAPGPKGSK GETGPQGSPGETGLAGLPGPI---GPR---GQPGPPGPPGPG--YEAGF--------GDM EGS--GIPIVSSV--PGPRGPEGPQGPPGLPGLKGDIGS------------SGQPGVPGQ KGDPGTPGTNGQPGLEGFPGPQGPKGDQGSPGVKGERGQDGVGLPGPPGPPGPPGEIVYA SN--------KTLA-VLPGPE---GRPGHAGFPGPVGP---------------------- -------------------KGEAGSPGLQGFPGMKGEKGEPGV-----IIGPDGTVTA-- --LDTKGEKGEPGLRGPVG------------------------PLGPHGRPGQKGEIGFP GRPGRPGMNGLKGEKGDPADPSGGFSLPGLPGPPGPPGPPGSPGSIVPV--YDG-NAFTE SGPPGPPGL--PGYQGVPGHKGEKGDTGAPGPPGQF-----------------P-YDLSR FGAAFRGEKGEQGDSGLKGEKGEPG--GGTLYGPGVVGQPGLPGPQ---GYPGLPGPKGD SIVGPPGPP-------GPQGPPGI-GYEGRQ---GPPGPPGPPGPP----SF-------- ------PG-PHRQ------------------------T-NVVGPP--GPPGPPGPP---G T-------SGTSASSG---------L-KILPSYQAMLSTAHEVPEGWLVFIVDREELYVR VRNGFRRILLEDHTVISS-TALDNEVYDKPPSIH-FAHGSSPSSGSQPHVPVHPHRDYNT YATV-----RPWGGD---------DIIANHHRLPKQPSIHQGAQ-----HQQEN------ --LHDFYPNRRP-EDTPSA----MHTHHDFQPALHLVALNTPLSGSM-RGIRGADFQCFQ QAREVGLTGTFRAFLSSRLQDLYSIVRRADRSSVPIVNLRDEVLFNNWESLFSG-TEAQL RAGAHILSFNGKDILRDSTWPQKSVW-HGSDSRGRRLTEN-YCETWRTDSSVVTGQASSL SSGKLLEQKASSCQNAFVVLCIENSFMTSSKK---------------------------- ----- >XP_019347546.1 PREDICTED: collagen alpha-1(XVIII) chain isoform X1 [Alligator mississippiensis] -------------------------------------MHDEIPAE------------VAG SLDNQL--SHYV-----------------------RNSNHSVSHGNTT------------ ------------------------------------------------------------ ---------P-------------------------------------------------- ------------------------------------------------------------ ----------HILKNADSSQSMQSIEP--------------------------------- -----------------------SDKQFGKAVADLNRSHSDSVSNA--TNFVDFFPANNS DSLGFDLLTYTMQLYSNNSTGLASFFPGLTPT---------------------------- ------------------------------------------------------------ ----------------------------------------AGHCLPLPANLPYCNNLGLK HFRM---PNYFNHGSDMEIRASLHEWEGLLKSRCHRYLEWFYCLLLVPGCNASIPITPPP CQGFCEALKDLCWMHLKEGHLPISCDS-------LPAEDNEYSCVFINVSAGNNDRGNIC YQLFLFLPPENFSTEVGLLQLIGDPPPEQITKIYGPDNNPGYVFGPDAN-TGQVARYHLP SPFYRDFSLLFHIQPTTNKAGVLFAITDSSQAVIYIGVKLSDAKEGKQHIIFYYTEPGSQ S-SYAAATFTVSSLLNQWTRFAVSVEDEEVVLFLDCE-EYDRIRFERSPD-EMELEDGSG LFVGQAGG-ADPDKYQGVIADLKIKNDPHAAVLQC--------------EE-DEDD---T EEMSGDFGSGVEEKL-HSSGKERGIPTVSGLP----KPPPVTSPPIAGRPVEKV--SGSS QLQTEH-IKAEETPPVST-----------GARVGQKGEKGEKGERGPKGDSRTGG----- ---VPSTGGVKGEKGEKGELGVKGSAGFGYP-GSKGQKGEPGAPGDPGPPGPPG------ ------------------PSGTILQHQDGSVVEHVTGPPGAMGPPGLPGKDGLPGK---- --------DGEPGDPGEDGKPGDTGPQGFPGTP-----GEPGLKGEKGDPGVSVKGSPGP PGPPGPPGI------PGLSSKQDKLTFIDMEGS-GFAGDLESLRGPRGPPGPPGPPGV-- -------------PGLPGEPGRFGMNHTA-IPGP---PGL-------------------- --------PGKDGSPGLQGPSGPPGPPGREGLPGQPGFRGEKGDSGDLGLPGAPGPKGSK GETGPQGSPGETGLAGLPGPI---GPR---GQPGPPGPPGPG--YEAGF--------GDM EGS--GIPIVSSV--PGPRGPEGPQGPPGLPGLKGDIGS------------LGQPGVPGQ KGDPGTPGTNGQPGLEGFPGPQGPKGDQGSPGVKGERGQDGVGLPGPPGPPGPPGEIVYA SN--------KTLA-VLPGPE---GRPGHAGFPGPVGP---------------------- -------------------KGEAGSPGLQGFPGLKGEKGEPGV-----IIGPDGTVTA-- --LDTKGEKGEPGLRGPVG------------------------PLGPHGRPGQKGEIGFP GRPGRPGMNGLKGEKGDPADPSGGFSVPGLPGPPGPPGPPGSPGSIVPI--YDG-NAFTE SGPPGPPGL--PGYQGVPGHKGEKGDTGAPGPPGQF-----------------P-YDLSR FGAAFRGEKGEQGDSGLKGEKGEPG--GGTLYGPGV-GQPGLPGPQ---GYPGLPGPKGD SIVGPPGPP-------GPQGPPGI-GYEGRQ---GPPGPPGPPGPP----SF-------- ------PG-PHRQ------------------------T-NVVGPP--GPPGPPGPP---G T-------SGTSASSG---------L-KILPSYQAMLSTAHEVPEGWLVFIVDREELYVR VRNGFRRILLEDHTVISS-TALDNEVYDKPPSIH-FARGSSPSSGSQPHVPVHPHRDYNT YATV-----RPWGGD---------DIIANHHRLPKQPSIHQGAQ-----HQQEN------ --LHDFYPNRRP-EDTPSA----MHTHHDFQPALHLVALNTPLSGSM-RGIRGADFQCFQ QAREVGLTGTFRAFLSSRLQDLYSIVRRADRSSVPIVNLRDEVLFNNWESLFSG-TEAQL RAATHILSFNGKDILRDSTWPQKSVW-HGSDSKGRRLTEN-YCETWRTDSSVVTGQASSL SSGKLLEQKASSCQNAFIVLCIENSFMTSSKK---------------------------- ----- >XP_020730828.1 collagen alpha-1(XVIII) chain [Odocoileus virginianus texanus] -------------------------------------MAPDPSSRRRGHHGLLLFACCLS AAQADL--LSWL-W----------------------PGNSAQPTAAPA-SKPRG-SSPVW PT---EATT----------THMAPRDAPTDW----------------------------- WKDSASPTAPLGRLE--------------------------------------------- --------------------AGQGQSPAGPMA---STASLD------LKEENIAGVG--- ---------AKILNVAQGIRSFVQLWDDAKDTTPAESSGRAGTPAPATPADSLSTAPAEG SGRAGMPPPADTTDPLSTPGPSSTPQDSGTTLQPSTGALSSPDTQR---TEASTLPVPTQ LPPSLGRPW------------FRESLVPPTP----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------EGEVVEVGLQQLLGEPPPWQVAVVHDPDVGPAYEFGEDGSGGGQAARRLLP SAFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTAARGGRQHVQLLYTEPGAT H-TGTAASFELPALDGRWTRLALSVDGAYARLFVDCQ-EVQGQPLAQSLH-DLHLEPDAR LFVAQAGG-ADPEKFQGLISELRLRRDPRVSPRHCQ-------------DEDEDDD---D DGASGDLGSGLVETQ-EHLREELGASLGPRLP----EAPPVTSPPLAG---------AGN EEDLRT-EEVEESTTVSS--------------LGAQTFPS-------------------- ---LGTVSTWDESVWKPGSSMKER--------GLKGQKGEPGAQGPPGPIGPQG------ ------------------PAGPAIDSHKGQPVSGPQGPP---GPPGPPGKDGTPGR---- --------DGEPGDPGEDGKPGDTGPQGFPGTP-----GDVGPKGEKGDPGV---GPRGP PGPQGPPGP------PGPSFKPDRLTFIDMEGS-GFGGDLESLRGPRGFPGPPGPPGV-- -------------PGLPGEPGRFGMNSSD-VPGPAGLPGV-------------------- --------PGRDGPPGLPGPPGPPGTPGKDGQPGLTGQKGSLGE------AGAPGPKGSK GDPGPIGAPGEHGLAGAPGPA---GP---PGPPGPPGPPGPG--FAAGF--------DDM EGS--GNVFWSTA-----RGADGLQGPPGTPGVKGDPGA------------VGPPGSKGE VGADGSPGLPGLPGREGAAGPQGPKGEKGTQGEKGDPGKDGVGQPGLPGPPGPPGPVVYV SEQD------RVLA-SVPGPE---GRAGFAGFPGPAGP---------------------- -------------------KGDLGAKGQQGIPGPKGEKGEPGT-----FFGPDGRTLT-- --PAQKGAKGEPGFRGPP---------------------------GPYGRPGHKGEIGFP GRPGRPGMNGLKGEKGEPGDASVGFGMRGPPGPPGPPGPPGPPGTPV----YDS-NAFVD SGRPGPPGL--PGHQGPSGPKGDKGDVGPPGPPGQF-----------------P-FDLLQ LGAEIKGEKGDRGAAGQKGERGEPG--GGGFFGSGV---PGPPGPP---GYPGIPGPKGE SIRGQPGPP-------GPQGPPGT-GYEGRQGPPGPPGPPGPPGPP----SF-------- ------PG-PYRQ------------------------TISVPGPP--GPPGPPGPP---G S-------MGTS--SG---------V-RVWATYQMLVEQVLQVPEGWLIYVADREELYVR VRNGFRKVL-------------DNEVAVLQPPLVQLHEGN------------PYPRREAP HPTA-----RSWRAD---------DILASPPRLPH-PQPYPGAP---------------- --HHGAYAHLRPVPPTASP----SHTHHDFQPVLHLVALNSPQSGGL-RGIRGADFQCFQ QARAAGLAGTFRAFLSSRLQDLYSIVRRADRATLPVVNLR--VCARPCLGLTSG-DSCPR LRGALV----AHQLGEVAGSPQAVMLCCGSHPRTRALHRAVFCGSFPEQNSAF------- ------------------------------------------------------------ ----- >XP_040213558.1 collagen alpha-1(XVIII) chain isoform X1 [Rana temporaria] -------------------------------------MARARLC--PVLAVLLLVVTLPA LSQAQF--LNWLGWGAKPTILATPTAKITTDSAILATTTTAAPNSSAT-SSPEGSSLPAA VTVVDNETSSTGRDEKDLTPATSPSSQPAAT----------------------------- ASLSAGVSSPSNQTSVPAAAATTNPNALTTHKQPVGTGTTEASLNRQLRIPESPETVKKP PEN--QIFSIFQVQEEE-LSSGSDAQPATPTSKNVPTSAPEASTTHKSEDKNIAGVG--- ---------AEILNVAENIRNFMNVWE---EKAKDLMTSTDNPPAEQGL----------- ------------GELINMTLPT---NQSGDLSQYGTGQADSANTTE---THARS-----Q LALSNNQTLNVTQVP-------SGNVTSAQP----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------DRENVEVGLLQLIGDPPPEEITKIFGPDRTPGYVFGEDAN-TGQVAQYHLP SPMFRDFSILFHIQPTTTKAGMLFSITDASQSIVYIGVKLSEVKDGKQQIIFFYTEPGST V-TFPAATFSVPALTNQWTRFALSVEEEEVALFMECN-ELKRVRFERSPD-EMELEDGSG LFVAQAGG-ADPDRYQGVIAEIKIKNDPRAAELQC--------------EE-EGDD---S DGASGDFGSGLSEEE------VVEVTRAPKVI----AVAPMTVPPIQR---------PSV VNEPKVIKEVQETIQRVEV---------SGK-PGQKGEKGDLGDRGMKGEIGPFGPKGEI GDSTSAGIGPKGDKGQKGELGVKGDAGFGYN-GPKGQKGDPGASGPPGPPGVSG------ ------------------PS--VVQKADGSTVQQITGPR------GPPGPEGPPGK---- --------EGEPGDPGEDGKAGEVGPQGFPGTP-----GDAGKKGDKGDPGV---GLRGP PGLPGPPGP------PGPGTKTDKLTFIDMEGS-GYGPDLENFRGPSGLPGPPGPPGV-- -------------PGLPGVPGTFGGNSTA-IPGPPGLPGR-------------------- --------PGQD---GMAGPPGPPGLPGKDGNPGTAGLAGERGTDGDIGLPGAPGSKGST GEPGIPGTPGETGLAGLPGPI---GPRGLPGPPGPPGPSGRG--TADGF--------DDM EGS--GITF----------GGRAIQGRPGIPGEKGDAGF------------------TGP KGDRGIPGLDGRPGLDGFPGPEGQKGNRGDQGERGEPGRDGI---GIPGPPGPPGQIIYR SSDG------ADII-GGIG-------------EGTRGY---------------------- -------------------KGETGEQGYPGLPGLKGDKGEAGR-----ILGPDGSLFT-- --GGVKGDTGPRGPSGPM---------------------------GPVGPSGQKGEIGFP GRPGRPGVNGLKGEKGETADPT-GYGIR---GPAGPPGPPGPPGQAV----YGDPRA--- AGPQGYPGQ--KGERGIPGTKGDQGDVGPAGPPGTF-----------------P-YDFSS FG------------RGEKGEKGEPS--VGD--GQGI---QGPPGNP---GYPGLPGAKGD SIQGPPGPR-------GPPGAAGV-GYEGRQ---GPPGPPGPPGAPAQQ-VYP------- -----GPG-PNRP------------------------VLSVPGPP--GPPGPPGPQ---G G-------SGGY--SS---------A-TVLQTFQTMINLRQSLQEGTIVLVLETADLYVR VRDGFRKILLGEY--VTG-NGQGNEIAAKEPPVVIYPSGNRDSGSYQSTDEYEPPRNERP PPVN--------------------------PRPPQPPP---------------------- ------QVFPKPEPEDNVP----VHTHQEYQAALHLVALNAPLTGSM-RSIRGVDFQCFE QARKAGLHGTFRAFLSSRLQDLYSIVRKADRLSVPIVNLRDEPLFDNWEALF-G-SEGQM NPGARIYSFEGRDVATDSTWPQKMIW-HGSDAKGRRLTES-YCETWRTDEGIVTGQASSV TNGKLLEQRPQSCNKNFIVLCIENSFMPAGQK---------------------------- ----- >XP_030830245.1 collagen alpha-1(I) chain isoform X3 [Strongylocentrotus purpuratus] -------------------------------------ML--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------LRPYSGSRGTVFGVTDPYHQTIILSVNITSMSIEQMRISLILTNIDYT SESTEVAAFLVPSFTNHWTQLALSIRDNQVTLFLDCQ-ELGMQFFDKNQGWHIRIPQMAP LFIGHLGTVGERVQYRGDIQQIIITNSADSAEEHCPIGEISGSGSMALRES-AGEDWAFV FSGSGDEPTSMPEMP--ITYFTQYDAETPSTPANNVRLPASVQPPLEQ-VATILPKAPPT TPTLQA-TPSSQPAVVVPP---------GDSMKGQKGEEGWPGVNGIHGNPGVPGPRG-- ---VGGETGPEGPEGPMGPKGEKGDLGDAGPVGPLGEEGFPGVAGPPGDPGVKG------ --------------------------EEGD--QGMTGATGAKGEPGV-GVPGLPGVAPTL SSEYMMRLGGEKGDPGRDGYPGVPGVQGPMGIPGVDGIGVPGPKGDKGEVGLGLPGSQGK PGKEGPKGETGQRGLPGPSSLE---SFI--EGS-G----LEMFVGPPGQPGSPGRPGVMG PHGPRGESGLDGIPGLDGVPGQPGPAGRDGEPGPKGEPGALTEEEILDEIANLTAEFEME GLSGMDGFNGSRGPPGVPGAVGPKGDSGMDGNPGMKGERGSSG------LPGLEGPEGMK GGPGQNGIPGVPGIAGIPGESGQNGARGAPGPAGPPGPPGPSPLLPPGFPWTNMALNQDQ EGSADGSGVWSGTVPPYLMGSPGVQGPPGPEGMQGEPGLVGEPGIPGEPAIPGMPGLTGE RGERGLPGPRGMEGETGMDGAAGQKGDTGDPGVPGQPGADGFPGPRGVGVQGPPGD---- ------R--------GLPGPR---GIQGLKGDVGEQGPACEIPPEILALSEHFAGVGSGD IGGGMMTRAPQELTSTKGEKGDIGFDGVPGMDGQQGAKGYPGPRGPGGVVGPKGNNGT-- --QGEKGDVGAVGYAGPRGVKGDKGDMFLPTEEEMLMLKGDGGDTGRRGKKGLKGQFGIP GRPGRVGKTGPEGQTG-------------PEGPVGPQGPPGPSGGGEGTCECDP-AAF-- -----PPAFFPPGEKGSMGAPGSPGPMGPDGVPGAPGLPGVQGLRGLQGYAGEPGIEGLE GRPGAQGVPGVPGIDGARGEKGDPG--DFFVNDEVF---IGPPGEQ---GLPGRDGQPGQ SIKGDTGEPGH-----GAEGMPGRDGRDGSQ---GPPGPPGMPGHPGEP-AYYTGDGNGE RGPKGEPGEPGREGQSGAPGFDGRPGSRGPRGPQGPTGYGEQGPP--GEPGTPGEP---G RGSIGHLGGGDY--VG---------M-ARFATIQDMLDGMRDLEVGTLAFIIRVQELYIR VETGMQQVLLGATFTLPP-------TSEPRPQPRPQPRPQ-------PSITSRTTTTTLI PTTT----LAPFVDP------------TEPPQIPG-----PGLT---------------- ---------DRTEEPILPG----PEIPVSDQPMLYMYALNTPQEGYMIGGISGADFKCWK QAKAAGLKGTYRAFLSSPLQDIRTIVRKQDK-GLPIANGKQEVLFNSWDDIFSTENEAPF HDSFHIYSFDGKDVMTDETWPDKYMW-HGSYANGERMAES-FCEAWRAQNHFARGQASPL SDHKLLGQDEFPCNNAFAVLCVQTARPNARK----------------------------- ----- >AEL31277.1 multiplexin collagen isoform Ap3 [Drosophila melanogaster] -------------------------------------MR--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------VLQGVMFALAMIC--------------------------------- ------------------------------------------------------------ ----------------------TLLVPVLGS----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------FELVGQSI--------- ---------KDALAEYTLTDIMNNNQFAGIEFGEAEDGFPAFRFLQTAD-VKSPYRMLLP EKLY-EFAILITFRQSSLKGGYLFSVVNPLDTVVQLGVHLSPVVKNSYNVSLVYTQADQN I-GRKLASFGVAHVPDKWNSIALQVLSDKVSFYYDCE-LRNTTLVTREPI-ELVFDSAST LYIGQAGS-IIGGKFEGYLEKINVYGNPDAINVTC------------------------- ------------------------------MP-----------PPKAT------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------IAPTTADDGSIFY--EGS-G------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------ENILF-------EDST EAN--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------ILSDD------- ---------------------------F-------------------------------- ---------------------------------------------------WNT------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------GDEATDIF-DASGMQ----------PPGQT----QY-----N-- ---------KHEE------------------------TLGLVDGE--EPYFSASSS---N M------NMKIV--PG---------A-VTFQNIDEMTKKSALNPPGTLAYITEEEALLVR VNKGWQYIALGTLVP----------IATPAPPTTVAPSMR-------------------- ---------FDLQSK---------NLLNSPPPLLN-TPTFTTAP---------------- --EYETW----------------------YPRMLRVAALNEPSTGDL-QGIRGADFACYR QGRRAGLLGTFKAFLSSRVQNLDTIVRPADR-DLPVVNTRGDVLFNSWKGIFNG-QGGFF SQAPRIYSFSGKNVMTDSTWPMKMVW-HGSLPNGERSMDT-YCDAWHSGDHLKGSFASNL DGHKLLEQKRQSCDSKLIILCVEALSQDRKRKKREIGDGSSHGESESREFKTADEYAAHL ENLLL >PNJ05978.1 COL18A1 isoform 2 [Pongo abelii] -------------------------------------MAPDPRG----CRILLLLFCSLA AARADLLNLNWL-W----------------------FNNEDTSHAATTIPEPQG-PLPAQ P------------------THMAPRNGSTEP----------------------------- ATVPGSPEPPSELLE--------------------------------------------- --------------------DGQDTPT--------SAESPD------TPEENIAGVG--- ---------AKILNVAQGIRSFVQLWN---DTVPTESLTRAETLVLETP----------- ------------VGPFALPGPSSTPQENGTTLWPSRGTPSSPGAHT---TEAGTLPAPTP SPPSLGRPWAPLT---------GPSVPPSSS----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ERVSEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDAN-SGQVARYHFP SLFFRDFSLLFHIRPATEGPGVLFAITDSAQAVVLLGVKLSGVQDGHQDISLLYTEPGAG Q-THTAASFRLPAFVGQWTHLALSVEGGYVTLYVDCE-EFQRMLLARSSR-GLELEPGAG LFVAQAGG-ADPDKFQGMIAELKVRGDPQVSPMHCL-------------DE-EGDD---S DGASGDFGSGLGDAR-ELLREETGAALKPRLP----MPPPVTTPPLAG---------GSS TEDSRS-KEIEEQTTVAS--------------LGGQTLPG-------------------- ---SDSVSTWDGSVRTPGDRVREG--------GLKGQKGEPGVPGPPGRAGPPGSPCLPG PPGLPCPVSPLGPAGPASPLGPA--GPALQPVPGPQ------GPPGPPGRDGTPGR---- --------DGEPGDPGEDGKPGDTGPQGFPGTP-----GDVGPKGDKGDPGV---GERGP PGPQGPPGP------PGPSFRHDKLTFIDMEGS-GFGGDLEALRGPRGFPGPPGPPGV-- -------------PGLPGEPGLFGVNSSD-VPGPAGLPGV-------------------- --------PGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGE------AGAPGHKGSK GDPGPAGARGESGLAGSPGPA---GP---PGPPGPPGPPGPG--LPAGF--------DDM EGS--GGPFWSTA-----RSADGPQGPPGLPGLKGDPGM------------PGLPGAKGE VGADGAPGFPGLPGREGIAGPQGPKGDRGSQGEKGDPGKDGVGQPGLPGPPGPPGPVVYV SEQD------GSVL-SVPGPE---GRPGFAGFPGPAGP---------------------- -------------------KGDLGSKGERGSPGPKGEKGEPGS-----IFRPDGGALG-- --PVQKGAKGEPGFRGPP---------------------------GPYGRPGYKGEIGFP GRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPV----YDS-NVFAE SSRPGPPGL--PGNQGPPGPKGAKGEVGPPGPPGQF-----------------P-FDFLQ LEAEMKGEKGDRGDAGQKGERGEPG--GGGFFGSRLPGPPGPPGPP---GYPGIPGPKGE SIRGQPGPP-------GPQGPPGI-GYEGRQGPPGPPGPPGPPGPP----SF-------- ------PG-PHRQ------------------------TISVPGPP--GPPGPPGPP---G T-------VGAS--SG---------V-RLWATRQAMLGQVHEVPEGWLIFVAEQEELYVR VRNGFRKVQLEARTPLPR--GTDNEVAALQPPVVQLHDSN------------PYPRREHP HPTA-----RPWRAD---------DILASPPRLPE-PQPYPGAP---------------- --HHSSYVHLRPARPTSPP----AHTHRDFQPVLHLVALNSPLSGSM-RGIRGADFQCFQ QARAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSG-SEGPL KPGARIFSFDGKDVLRHPTWPQKSVW-HGSDPNGRRLTES-YCETWRTEAPSATGQASSL LGGRLLGQNAASCHHAYIVLCIENSFMTASK----------------------------- ----- >XP_043330533.1 collagen alpha-1(XVIII) chain isoform X5 [Cervus canadensis] MGSWLLAGDGWGSGRRSGLAPPPDSRGRLLLRGAHSPMAPDPSSRRRGHYGLLLLACCLS AAQADL--LSWL-W----------------------PGNSAQPTAAPA-SKTPG-SSPVW PT---EDTT----------THVAPRDAPTDW----------------------------- WKVSASPTTPLQRPE--------------------------------------------- --------------------AGQGQSPAGPTA---STASLD------LKEENIAGVG--- ---------AKILNVAQGIRSFVQLWDDTKDTTPAESSARAGTPAPTTPTDPLSTAPAKG SARAGMPPPTDTTDPLSTPGPSSTPQDSGTTLQPSTGALSSPDTQR---TEAGTLPVPTQ LPPSLGRPW------------FRESLVLPTP----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------EGEVMEVGLQQLLGEPPPWQVAVVHDPDVGPAYEFGEDGSGGGQAARGFLP SAFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTAARGGRQHVQLLYTEPGDT H-TRTAASFELPALDGRWTRLALSVDGAYARLFVDCK-EVQGQPLAHSLH-DLHLEPDAR LFVAQAGG-ADPEKFQGLISELRLRRDPRVSPRHCQ-------------DEDEDDD---D DGASGDLGSGLVETQ-EHLREELGASLGPRLP----EAPPVTSPPLAG---------VGN EEDLRT-EEVEESTTVSS--------------LGAQTLPS-------------------- ---LGTVSMWDKSVWSPGSSMEER--------GLKGQKGEPGAQGPPGPIGPQG------ ------------------PAGPAIESHEGQPVSGPQGPP---GPPGPPGKDGTPGR---- --------DGEPGDPGEDGKPGDTGPQGFPGTP-----GDVGPKGEKGDPGI---GPRGP PGPQGPPGP------PGPSFKPDRLTFIDMEGS-GFGGDLESLRGPRGFPGPPGPPGV-- -------------PGLPGEPGRFGMNSSD-VPGPAGLPGV-------------------- --------PGRDGLPGLPGPPGPPGTPGKDGQPGLTGQKGSLGE------AGAPGPKGSK GDPGPIGAPGEHGLAGAPGPA---GP---PGPPGPPGPPGPG--FAAGF--------DDM EGS--GNVFWSTA-----RGADGLQGPPGTPGVKGDPGA------------VGPPGSKGE VGADGAPGLPGLPGGEGAAGPQGPKGEKGTRGEKGDPGKDGVGQPGLPGPPGPPGPVVYV SEQD------RVLA-SVPGPE---GRTGFAGFPGPAGP---------------------- -------------------KGDLGAKGQQGIPGPKGEKGEPGT-----FFGPDGRALT-- --PAQKGAKGEPGFRGPP---------------------------GPYGRPGHKGEIGFP GRPGRPGMNGLKGEKGEPGDASVGFGMRGPPGPPGPPGPPGPPGTPV----YDS-NAFVD SGRPGPPGL--PGHQGPSGPKGDKGDVGPPGPPGQF-----------------P-FDLLQ LGAEMKGEKGDRGAAGQKGERGDPG--GGGFFGSSV---PGPPGPP---GYPGIPGPKGE SIRGQPGPP-------GPQGPPGI-GYEGRQGPPGPPGPPGPPGPP----SF-------- ------PG-PYRQ------------------------TISVPGPP--GPPGPPGPP---G S-------MGTS--SG---------V-RVWATYQMLVEQVLQVPEGWLIYVADREELYVR VRNGFRKVLLEAHVPLPH--GTDNEVAVLQPPLVQLHEGN------------PYPRREAP HPTA-----RSWRAD---------DILANPPRLPH-PQPYPGAP---------------- --HHGAYAHLRPVPPTASP----SHTHHDFQPVLHLVALNSPQSGGL-RGIRGADFQCFQ QARAAGLAGTFRAFLSSRLQDLYSIVRRADRATLPVVNLRDEVLFPSWEALFSG-SEGQL KPGARIFSFDGRDVLQHPAWPQKSVW-HGSDPSGRRLTES-YCETWRTDTRAATGQASSL LAGRLLEQKAAGCHNAFIVLCIENSFMTSSSK---------------------------- ----- >XP_043729625.1 collagen alpha-1(XVIII) chain isoform X5 [Cervus elaphus] MGSWLLAGDGWGSGRRSGLAPPPDSRGRLLLRGAHSPMAPDPSSRRRGHYGLLLLACCLS AAQADL--LSWL-W----------------------PRNSAQPTAAPA-SKTPG-SSPVW PT---EDTT----------THVAPRDAPTDW----------------------------- WKVSASPTTPLQRPE--------------------------------------------- --------------------AGQGQSPAGPTA---STASLD------LKEENIAGVG--- ---------AKILNVAQGIRSFVQLWDDTKDTTPAESSARAGTPAPTTPTDPLSTAPAKG SARAGMPPPTDTTDPLSTPGPSSTPQDSGTTLQPSTGALSSPDTQR---TEAGTLPVPTQ LPPSLGRPW------------FRESLVLPTP----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------EGEVMEVGLQQLLGEPPPWQVAVVHDPDVGPAYEFGEDGSGGGQAARGFLP SAFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTAARGGRQHVQLLYTEPGDT H-TRTAASFELPALDGRWTRLALSVDGAYARLFVDCK-EVQGQPLAHSLH-DLHLEPDAR LFVAQAGG-ADPEKFQGLISELRLRRDPRVSPRHCQ-------------DEDEDDD---D DGASGDLGSGLVETQ-EHLREELGASLGPRLP----EAPPVTSPPLAG---------VGN EEDLRT-EEVEESTTVSS--------------LGAQTLPS-------------------- ---LGTVSMWDKSVWSPGSSMEER--------GLKGQKGEPGAQGPPGPIGPQG------ ------------------PAGPAIESHEGQPVSGPQGPP---GPPGPPGKDGTPGR---- --------DGEPGDPGEDGKPGDTGPQGFPGTP-----GDVGPKGEKGDPGI---GPRGP PGPQGPPGP------PGPSFKPDRLTFIDMEGS-GFGGDLESLRGPRGFPGPPGPPGV-- -------------PGLPGEPGRFGMNSSD-VPGPAGLPGV-------------------- --------PGRDGLPGLPGPPGPPGTPGKDGQPGLTGQKGSLGE------AGAPGPKGSK GDPGPIGAPGEHGLAGAPGPA---GP---PGPPGPPGPPGPG--FAAGF--------DDM EGS--GNVFWSTA-----RGADGLQGPPGTPGVKGDPGA------------VGPPGSKGE VGADGAPGLPGLPGGEGAAGPQGPKGEKGTRGEKGDPGKDGVGQPGLPGPPGPPGPVVYV SEQD------RVLA-SVPGPE---GRTGFAGFPGPAGP---------------------- -------------------KGDLGAKGQQGIPGPKGEKGEPGT-----FFGPDGRALT-- --PAQKGAKGEPGFRGPP---------------------------GPYGRPGHKGEIGFP GRPGRPGMNGLKGEKGEPGDASVGFGMRGPPGPPGPPGPPGPPGTPV----YDS-NAFVD SGRPGPPGL--PGHQGPSGPKGDKGDVGPPGPPGQF-----------------P-FDLLQ LGAEMKGEKGDRGAAGQKGERGDPG--GGGFFGSSV---PGPPGPP---GYPGIPGPKGE SIRGQPGPP-------GPQGPPGI-GYEGRQGPPGPPGPPGPPGPP----SF-------- ------PG-PYRQ------------------------TISVPGPP--GPPGPPGPP---G S-------MGTS--SG---------V-RVWATYQMLVEQVLQVPEGWLIYVADREELYVR VRNGFRKVLLEAHVPLPH--GTDNEVAVLQPPLVQLHEGN------------PYPRREAP HPTA-----RSWRAD---------DILANPPRLPH-PQPYPGAP---------------- --HHGAYAHLRPVPPTASP----SHTHHDFQPVLHLVALNSPQSGGL-RGIRGADFQCFQ QARAAGLAGTFRAFLSSRLQDLYSIVRRADRATLPVVNLRDEVLFPSWEALFSG-SEGQL KPGARIFSFDGRDVLQHPAWPQKSVW-HGSDPSGRRLTES-YCETWRTDTRAATGQASSL LAGRLLEQKAAGCHNAFIVLCIENSFMTSSSK---------------------------- ----- >KAB0373800.1 hypothetical protein FD755_014056 [Muntiacus reevesi] -------------------------------------MAPDPSSRRRGHHSLLLLACCLS AAQADL--LSWL-W----------------------PGNSAQPTAAPA-SKTLG-SSPVW PT---EDTT----------THVDPRDAPTDW----------------------------- WKVSASPTTPLQRPE--------------------------------------------- --------------------AGQGQSPAGPTA---STASLD------LKEENIAGVG--- ---------AKILNVAQGIRSFVQLWDDAKDTTPAESSARAGTPAPTTPTDPLSTAPAKG SARAGMLPPTDTTDPLSTPGPSSTPQDSRTTLQPSTRALSSPDTQR---TEADTLPLPTQ LPPSLGRPW------------FRESLVPPTP----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------EGEVVEVGLQQLLGEPPPWQVAVVHDPDVGPAYEFGEDGSGGGQAARGLLP SAFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTAARGGRQHVQLLYTEPGDT H-TRTAASFELPALDGRWTRLALSVDGAYARLFVDCK-EVQGQPLAHSLH-DLHLEPDAR LFVAQAGG-ADPEKFQGLISELRLRRDPRVSPRHCQ-------------DEDEDDD---D DGASGDLGSGLMETQ-EHLREELGASLGPRLP----EAPPVTSPPLAG---------VGN EEDLRT-EEVEESTTVSS--------------LGAQTLPS-------------------- ---LGTVSTWDESVWSPGSSMKER--------GLKGQKGEPGAQGPPGPIGPQG------ ------------------PAGPAIESHEGQPVSGPQGPP---GPPGPPGKDGTPGR---- --------DGEPGDPGEDGKPGDTGPQGFPGTP-----GDVGPKGEKGDPGV---GPRGP PGPQGPPGP------PGPSFKPDRLTFIDMEGS-GFGGDLESLRGPRGFPGPPGPPGV-- -------------PGLPGEPGRFGMNSSD-IPGPAGLPGV-------------------- --------PGRDGPPGLPGPPGPPGTPGKDGQPGLTGQKGSVGE------AGAPGPKGSK GDPGPIGAPGEHGLAGAPGPA---GP---PGPPGPPGPPGPG--FAAGF--------DDM EGS--GNVFWSTA-----RGADGLQGPPGTPGVKGDPGA------------VGPPGSKGE VGADGAPGLPGLPGREGAAGSQGPKGEKGTQGEKGDPGKDGVGQPGLPGPPGPPGPVVYV SEQD------RVLA-SVPGPE---GRAGFAGFPGPAGP---------------------- -------------------KGDLGAKGQQGIPGPKGEKGEPGA-----FFGPDGRALT-- --PAQKGAKGEPGFRGPP---------------------------GPYGRPGHKGEIGFP GRPGRPGMNGLKGEKGEPGDASVGFGVRGPPGPPGPPGPPGPAGTPV----YDS-NAFVD SGRPGPPGL--PGHQGPSGPKGDKGDVGPPGP---------------------P-VLLLQ VG-EIRSSSWTPGHCQPKGDRGQGS--GGG-ASSSL---P-------------FKLSKAE G-RGQHGARPTCWEVGQAEGGQTC-GVRTCESGKGQAG---------------------- -----------RT------------------------AVTAAPPPALGPPGTASPC---G V-------MGTG--SG---------Q-RVWATYQMLVEQVLQVPEGWLIYVADREELYVR VRNGFRKVLLEAHVPLPH--GTDNEVAVLQPPLVQLHEGN------------PYPRREAP HPTA-----RAWRAD---------DILANPPRLPH-PQPYPGAP---------------- --HHGAYAHLRPVPPTASP----SHTHHDFQPVLHLVALNSPQSGGL-RGIRGADFQCFQ QARAAGLAGTFRAFLSSRLQDLYSIVRRADRATLPVVNLRDEVLFPSWEALFSG-SEGQL KPGARIFSFDGRDVLQHPAWPQKSVW-HGSDPSGRRLTES-YCETWRTDTRAATGQASSL LAGRLLEQKAAGCHNAFIVLCIENSFMTSSSK---------------------------- ----- >KAB0366097.1 hypothetical protein FD754_010253 [Muntiacus muntjak] -------------------------------------MAPDPSSRRRGHHSLLLLACCLS AAQADL--LSWL-W----------------------PGNSAQPTAAPA-SKTPG-SSPVW PT---EDTT----------THVDPRDAPTDW----------------------------- WKVSASPTTPLRRPE--------------------------------------------- --------------------AGQGQSPAGPTA---STASLD------LKEENIAGVG--- ---------AKILNVAQGIRSFVQLWDDAKDTTPAESSARAGTPAPTTPTDPLSTAPAEG SARAGMPPPTDTTDPLSTPGPSSTPQDSRTTLQPSTRALSSPDTQR---TEAGTLPLPTQ LPPSLGRPW------------FRESLVPPTP----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------EGEVVEVGLQQLLGEPPPWQVAVVHDPDVGPAYEFGEDGSGGGQAARGLLP SAFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTAARGGRQHVQLLYTEPGAT H-TRTAASFKLPALDGRWTRLALSVDGAYTRLFVDCK-EVQGQPLAHSLH-DLHLEPDAR LFVAQAGG-ADPEKFQGLISELRLRRDPRVSPRHCQ-------------DEDEDDD---D DGASGDLGSGLMETQ-EHLREELGASLGPRLP----EAPPVTSPPLAG---------VGN EEDLRT-EEVEESTTVSS--------------LGAQTLPS-------------------- ---LGTVSTWDESVWSPGSSMKER--------GLKGQKGEPGAQGPPGPIGPQG------ ------------------PAGPDIESHEGQPVSGPQGPP---GPPGPPGKDGTPGR---- --------DGEPGDPGEDGKPGDTGPQGFPGTP-----GDVGPKGEKGDPGV---GPRGP PGPQGPPGP------PGPSFKPDRLTFIDMEGS-GFGGDLESLRGPRGFPGPPGPPGV-- -------------PGLPGEPGRFGMNSSD-IPGPAGLPGV-------------------- --------PGRDGPPGLPGPPGPPGTPGKDGQPGLTGQKGSVGE------AGAPGPKGSK GDPGPIGAPGEHGLAGAPGPA---GP---PGPPGPPGPPGPG--FAAGF--------DDM EGS--GNVFWSTA-----RGADGLQGPPGTPGVKGDPGA------------VGPPGSKGE VGADGAPGLPGLPGREGAAGPQGPKGEKGTQGEKGDPGKDGVGQPGLPGPPGPPGPVVYV SEQD------RVLA-SVPGPE---GRAGFAGFPGPAGP---------------------- -------------------KGDLGAKGQQGIPGPKGEKGEPGA-----FFGPGPRALT-- --PAQNGAKGEPGFRGPP---------------------------GPYGRPGHKGEIGFP GRPGRPGMNGLKGEKGEPGDASVGFGVRGPPGPPGPPGPPGPAGTPV----YDS-NAFVD SGRPGPPGL--PGHQGPSGPKGDKGDVGPPGP---------------------P-VLLLQ VG-EIRSSSWTPGHCQPKGDRGQGS--GGG-ASSSL---P-------------FKLSKAE G-RGQHGARPTCWEVGQAEGGQTC-GVRTCESGKGQAG---------------------- -----------RT------------------------AVTAAPPPALGPPGTASPC---G M-------MGTG--SG---------Q-WVWATYQMLVEQVLQVPEGWLIYVADREELYVR VRNGFRKVLLEAHVPLPH--GTDNEVAVLQPPLVQLHEGN------------PYPRREAP HPTA-----RSWRAD---------DILANPPRLPH-PQPYPGAP---------------- --HHGAYAHLRPVPPTASP----SHTHHDFQPVLHLVALNSPQSGGL-RGIRGADFQCFQ QARAAGLAGTFRAFLSSRLQDLYSIVRRADRAALPVVNLRDEVLFPSWEALFSG-SEGQL KPGARIFSFDGRDVLQHPAWPQKSVW-HGSDPSGRRLTES-YCETWRTDTRAATGQASSL LAGRLLEQKAAGCHNAFIVLCIENSFMTSSSK---------------------------- ----- >KAF4020675.1 hypothetical protein G4228_012853 [Cervus hanglu yarkandensis] -------------------------------------MAPDPSSRRRGHYGLLLLACCLS AAQADL--LSWL-W----------------------PGNSAQPTAAPA-SKTPG-SSPVW PT---EDTT----------THVAPRDAPTDW----------------------------- WKVSASPTTPLQRPE--------------------------------------------- --------------------AGQGQSPAGPTA---STASLD------LKEENIAGVG--- ---------AKILNVAQGIRSFVQLWDDTKDTTPAESSARAGTPAPTTPTDPLSTAPAKG SARAGMPPPTDTTDPLSTPGPSSTPQDSGTTLQPSTGALSSPDTQR---TEAGTLPVPTQ LPPSLGRPW------------FRESLVLPTP----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------EGEVMEVGLQQLLGEPPPWQVAVVHDPDVGPAYEFGEDGSGGGQAARGFLP SAFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTAARGGRQHVQLLYTEPGDT H-TRTAASFELPALDGRWTRLALSVDGAYARLFVDCK-EVQGQPLAHSLH-DLHLEPDAR LFVAQAGG-ADPEKFQGLISELRLRRDPRVSPRHCQ-------------DEDEDDD---D DGASGDLGSGLVETQ-EHLREELGASLGPRLP----EAPPVTSPPLAG---------VGN EEDLRT-EEVEESTTVSS--------------LGAQTLPS-------------------- ---LGTVSMWDESVWSPGSSMKER--------GLKGQKGEPGAQGPPGPIGPQG------ ------------------PAGPAIESHEGQPVSGPQGPP---GPPGPPGKDGTPGR---- --------DGEPGDPGEDGKPGDTGPQGFPGTP-----GDVGPKGEKGDPGI---GPRGP PGPQGPPGP------PGPSFKPDRLTFIDMEGS-GFGGDLESLRGPRGFPGPPGPPGV-- -------------PGLPGEPGRFGMNSSD-VPGPAGLPGV-------------------- --------PGRDGLPGLPGPPGPPGTPGKDGQPGLTGQKGSL---------------GSK GDPGPIGAPGEHGLAGAPGPA---GP---PGPPGPPGPPGPG--FAAGF--------DDM EGS--GNVFWSTA-----RGADGLQGPPGTPGVKGDPGA------------VGPPGSKGE VGADGAPGLPGLPGGEGAAGPQGPKGEKGTRGEKGDPGKDGVGQPGLPGPPGPPGPVVYV SEQDCGQPLRGVVL-TVLSPQ---GRTGFAGFPGPAGP---------------------- -------------------KGDLGAKGQQGIPGPKGEKGEPGT-----FFGPDGRALT-- --PAQKGAKGEPGFRGP------------------------------------------- --PGRPGMNGLKGEKGEPGDASVGFGMRGPPGPPGPPGPPGPPGTPV----YDS-N---- ------------------------------------------------------------ ------GEKGDRGAAGQKGERGDPG--GGGFFGSSV---PGPPGPP---GYPGIPGPKGE SIRGQPGPP-------GPQGPPGI-GYEGRQGPPGPPGPPGPPGPP----SF-------- ------PG-PYRQ------------------------TISVPGPP--GPPGPPGPP---G S-------MGTS--SG--------QV-RVWATYQMLVEQVLQVPEGWLIYVADREELYVR VRNGFRKVL-------------DNEVAVLQPPLVQLHEGN------------PYPRREAP HPTA-----RSWRAD---------DILANPPRLPH-PQPYPGAP---------------- --HHGAYAHLRPVPPTASP----SHTHHDFQPVLHLVALNSPQSGGL-RGIRGADFQCFQ QARAAGLAGTFRAFLSSRLQDLYSIVRRADRATLPVVNLRDEVLFPSWEALFSG-SEGQL KPGARIFSFDGRDVLQHPAWPQKSVW-HGSDPSGRRLTES-YCETWRTDTRAATGQASSL LAGRLLEQKAAGCHNAFIVLCIENSFMTSSSK---------------------------- ----- >NP_001082208.1 collagen type XVIII alpha 1 S homeolog precursor [Xenopus laevis] -------------------------------------MILR------------------- --------CTWV------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------LLLYAAYH------------------------------------------ ------------------------------------------------------------ ----------------------ALLVSSQGK----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------DNFGLEVGLLQLIGEPVPSQITKVLGPDKTPAYVFDKEAN-TGQVAQYHLP NPMYRDFSLLFHVQPTTNKAGILFAITDASQXIVYIGVKLSEAKDGKQDIIFYYTEPGSR D-SYIAATFNVPSLVNRWSRFSISVEDEEVVLFMNCD-EMERVRFERSPD-EMELEDGSG LFVAQAGG-ADPDRYQGVIADLKIVADPRAAEQQC--------------ED-DGDD---S DGISGDFGSGIADND------LVTASPPVVIK----VQPPINVPPIQK---------NPV E------KEIVQTGQ------------------GQQGIKGEKGDRGEKGERGLTGPKGDS AS-VSLASDSKAEKGQKGEVGFKGSAGFGYP-GPKGQKGDPGIMGPRGHPGPPG------ ------------------PS--VLQKSDGTTVQQVTGPP------GPQGPAGPPGN---- --------DGEPGDPGEDGKTGEVGPQGFPGTP-----GDIGQKGEKGDSGV---GMRGP SGPPGPPGP------PGPS-RMDKLTFIDMEGS-GYGGDLENVRGPSGLPGPPGPPGV-- -------------PGLPGVPGTFGMNNTG-LPGPPGLPGL-------------------- --------PGKE---GFPGPPGPSGPPGKDGLTGAAGVAGIRGEDGEIGLPGAPGVKGSP GEPGQPGAVGQPGLAGLPGPM---GPRGLPGPPGPPGPVGRG--SAIGF--------DDM EAS--GLGF-------GPR--EGTQGLSGLPGAKGEQGN------------PGMPGLPGV KGESGSPGPEGRQGLDGFPGLEGLKGEKGEHGERGEPGRDGV---GIPGPPGPPGQVLYL PSDD------KSAVGAISGPE---GRQGVAGLPGPRGP---------------------- -------------------KGDQGLDGFPGTSGAKGERGEPGL-----IMRPDGTIYT-- --DLSKAEKGEQGPTGPA---------------------------GSVGPSGQKGEIGFP GRPGRPGMNGLKGEKGDPA--SGGFGLN---GPPGPPGPPGPPGSVV----YGDPNI--- -----PRAY--PGQKGERGFPGPKGDVGPAGPPGSF-----------------P-YDLST FASILTRE------AGLKGEKGEPG--GGD-NGQGI---PGPSGNP---GYPGLPGAKGE SVQGPPGPA-------GPPGHPGT-GYEGRQ---GPPGPPGPPGLPGSSSSY-------- ------PG-PHRQ------------------------TISIPGPP--GPPGPPGLP---G T-------SGGL--SG---------A-TVLQTYQTMINLAHRLQEGTIVLVQERAELYVR VREGFRKILLGEYSALSG-PGQDNEVAAEQAPVVPYPHRNKDSDYLQS--TEENSNNANV PSGA-----RPW-SD---------PRLPEPPRVDP-PRVDPPPP---------------- --DH--HHHGNPHPLEPSP----VHTHQQFNPALHLVALNAPLSGSM-KSIRGVDFQCFE QARKSGLHGTFRAFLSSRLQDLYSIVRRADRQSVQIVNLRDEVLYDNWESLFSG-SEAQM RPGARIFSFDGKDVATDPTWPQKMVW-HGSDAKGRRLTES-YCETWRTDESAVTSQASSL TSGKLLEQRPQSCNKNFIVLCIENSFMTNNRK---------------------------- ----- >XP_015820964.1 PREDICTED: collagen alpha-1(XVIII) chain [Nothobranchius furzeri] -------------------------------------MNMRC------------------ --------SSW------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------LERLVCCV---------------------------------- ------------------------------------------------------------ ----------------------LLLIPAAT------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------QREDNGVSLLQLIGDPPPDGIPQVDGPDNNPGYVFGPDTS-SGQMALAHFP SSFYRNFALIFSVKPTSDQGGVIFSITDSSQEVIDVGVRLAAVQGGHQDVIFYYNYLGKK N-SHEAARFPVPSMKDTWNWFAIAVQDDKVMFYHSCEGEPQVMRMERSAD-KLELESGAG VFVGGAGG-STHDKFEGVISELRVVGDPRAAERLC--------------EE-EDDD---S DMASGE-GSGVEGSE-VPNRYREKHRYTTTTP----SLPPIPQPPLNR---------KGE EATVRE-S---------------------GA-VGAKGEKGERGDRGEKGDRGAIGPKGEA GSGFGSRGGIRGEKGEPGERGLKGNAGFGYP----GKKGDPGPPGVPGPPGPPG------ ------------------PAAEYSVASDGSVVSRVPGPR---GPPGAPGSQGPPGE---- --------DGEPGDPGEDGKTGPQGPPGFPGTP-----GDSGQKGEKGDRGE---GQPGP RGLPGPPGA------PGPGY---RSTFEDMEAS-GF-SDLETVRGPRGPPGPPGPPGP-- ----------------PGPSTSGSTSNS-------GAFGP-------------------- --------PGKDGAPGLPGSP---GLPGSDGPPGAPGPRGEKGDSGELGLPGAIGQKGAQ GDLGLPGPPGEPGLAGLPGPM---GP---VGPPGPAGPPGPS--YRVGF--------DDM EGS-------SGL--TGIRGPEGIQGSPGLPGHPGEP---------------GLPGADGP KGDQGPTGKDGLPGLDGFPGPPGQKGDRGDKGETGDPGRDGTGLPGPPGPPGPPGQIIYQ PSDR-VRN--LDNFAG--GAQGGLGLPGRAGLPGPVGP---------------------- -------------------KGERGDPGPAGY-GVKGEKGEPGL-----IIGPDGAPLYLG GLTGQKGDRGPAGPVGPS---------------------------GPYGPPGLKGEIGMP GRPGRPGVNGYKGEKGEPGGGA-GYGYPGVAGPPGPPGPPGPPGPAIP---LDRYNAYDE ASR---------SYRVVKGDKGERGDR---GPPGTV-----------------SNFDIYT LKNQLKGD---RGDTGVKGEKGEPG--HG-YYDPRIEGLQGPPGPP---GNPGLPGPKGD SIVGPSGPQ-------GPPGPPGV-GYDGRPGPPGPPGPPGPATSP----SF-------- ------TG-THRPH----------------------YPVSVPGPP--GPPGPPGNP---G L-------SS-----G---------V-TVLRSYDTMIATARQQPEGSLIYIIDKADLYLR VREGLRQVMLGQYSPFSR--DLENEVVEVQPPPVIVYPHN-------------SQNNGAG HYSDSGSVIRPIEPP--------------------------------------------- --------QPRPHQPVPGS----TGLVETPESVLHLAALNAPQTGDM-RGIRGADFMCFQ QARAVGLKGTFRAFLSSKLQDLYTIVRTLDRKTFPIVNLKNQVLFTSWESIFRE-NSSKM RENVPIYSFDGRDVLRDSAWPEKMVW-HGSSSEGKRNMDH-YCETWRIDNHALTGLASSL QSGYLLQQNRSSCSGSYIVLCIENAFMSSSKK---------------------------- ----- >XP_030285041.1 collagen alpha-1(XVIII) chain isoform X1 [Sparus aurata] -------------------------------------MRTQF-------GVLLLLALWVV HTDAWF--WSW-------------------------TGTTTLP----------------- PT-VDNEGS--------------------------------------------------- GSQAGSGEPPS------------------------------------------------- --------------------------------------------------ENIARTG--- ---------LEIIDEGHGIQKVVQTET---TQAPRLTTTT-------------------- ---------------------------------------QPANEHA---SEKG------- ----------------------AAGISSRKH----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------KPEDSGVSLLQLIGDPPPSEIRRVYGFDNIPGYDFGPDAN-TGQLARAHLP SPFFRDFALIFYLKPTTDRGGVIFSVTDASQKIMYVGVKLSAVQGGNQNVILYYTEPDSQ Q-SYEAARFRVPSMRDTWTRFAIAVRDEKVMFYHNCDADPQVMRIERSPD-EMELEAGAG VFVGQAGG-ADPDKFLGVIGELRVVGDPRAAERHC--------------EE-DEDD---S DMASGD-GSGYVESK-PPKPAVDNPRWTTTPP----PSRPIQQPPVTK---------KEE VSVARE-T---------------------GP-DGAKGEKGDRGDRGEKGERGPIGPKGES GFGSSSRGGARGEKGEPGEKGLKGSAGFGYQ----GTKGEPGPAGPPGPAGPPG------ ------------------PATEFSVGSDGSVSSRGPGPRGPAGPPGSPGPKGPPGN---- --------DGEPGDPGEDGKTGPEGPPGFPGTP-----GDTGPKGDKGDRGD---GQPGP RGPPGPPGP------PGTGL---RSTFVDMEGS-GF-PDLDSIR---GLPGPQGPPGP-- -------------PGPPGPSTATTGLSS-------GAFGP-------------------- --------PGKDGAPGQPGLA---GLPGTDGLPGAPGPKGEKGDSGELGLPGAIGQKGAQ GEPGVPGTPGEAGLAGLPGPM---GP---VGQPGPPGPPGPS--YRVGF--------DDM EGS--GGGFSNGL--PGVRGPEGTQGSPGLPGLPGKP---------------GFPGMPGQ KGSEGSVGRDGQPGLDGFPGPKGPKGDKGDKGETGNPGRDGTGHPGPPGPPGPPGEIIYR TSDN------LDVAAGGAGPQGGPGLPGQAGFPGPIGP---------------------- -------------------KGDRGDPGPVGY-GVKGEKGEPGL-----IVGPDGNLLSLE GLTGVKGDRGPAGPVGPT---------------------------GPYGPPGLKGEIGMP GRPGRPGVNGYKGEKGEPSVGS-GYGYPGVPGQPGPPGPPGPPGPAIP---IDRFNRYDD SSR---------NYPATKGEKGERGDRGIPGIPGAA-----------------SNFDIYA FKNELKGE---RGETGVKGEKGEPS--GG-YYDPRFGGVQGPQGPP---GKPGLPGPKGE PVMGPPGPQ-------GPPGSPGI-GYDGRPGPPGPPGPPGPQ-SP----SLP------- -----GAG-AYRPN----------------------QPVSVPGPP--GPPGPPGSP---A L-------SS-----G---------V-SVLRSYDVMIATARRQAEGSLIYIIDKADLYLR VRDGLRQVMLGEYSPFFR--DLENEVAEVQPPPVILYPQS----------GDESQNNGAG HYSQGGSSIRPIEPPPQPPVEPRYP-PQYDPRFPD-PRRTGQTDGGLATRQTEN------ --RYPVTPQRRPSPPVVHP----VGHVDTSVSGLHLIALNAPQSGNM-RGIRGADFLCFQ QARAIGLKGTFRAFLSSKLQDLHTIVRRSDRDSLPILNLKDQVLFSSWEAIFGD-NASKM RENVPIYSFDGRDILRDSAWPEKMVW-HGSSNKGHRQTDH-YCETWRAGDRAVTGLASSL QSGHLLQQSSTSCSGSYIVLCIENAFTTHSKK---------------------------- ----- >XP_023806434.1 collagen alpha-1(XVIII) chain [Oryzias latipes] -------------------------------------MR--------------------- ----------W------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------NERLVCCVL--------------------------------- ------------------------------------------------------------ ----------------------LFVVPAALQ----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------WPEDNGVSLLQLIGDPPPSEISQVYGPDNAIGYVFGPDAK-MGQLAVAHFP TPFYRDFSLNFHLKPTSNEGGVVFSITDSSQQVIVVGVKLSTVERQTQDVIFYYSETGSE Q-SYEAARFQVTSMTDTWTRFSISVRDDKVAFYFNCDLSPVVKRFERSPD-DMELERGSG VFVGQTGG-PDPERFLGVISELRVVGDPRAAETFC--------------DE-DGDD---S DMASGE-GSGYEETR-PQKQNMDRNRFSTAPPF--PSFMSIQKPPLAT---------SGE EAVVRD-TAIKSEHMSVFVESGSRLHGSAGA-VGAKGEKGERGERGEKGDRGPAGPKGDS GPGSSSASGSRGEKGEPGEKGTKGSAGFGYQ----GKKGDPGQPGPPGPPGPPG------ ------------------PSTEYVPSSDGTVVSKVQGPR---GPPGPPGPQGQPGE---- --------DGEPGDPGEDGKTGSPGPQGFPGTP-----GDPGRKGDKGDRGE---GQPGP RGAPGPPGP------PGPGM---RSTFVDMEGS-GF-PDLESLR---GLPGPPGPPGP-- -------------PGPPGSSVTGPAMGS-------GAFGP-------------------- --------PGRDGAAGQP------GLPGTDGLPGAPGPKGDKGDAGDLGLPGAIGEKGDR GEPGLPGSPGESGLAGLPGPM---GP---VGPPGPPGPPGSN--YRVGF--------DDV EAS--GGRFTSGL---GIRGPQGAQGPPGLPGNPGRP---------------GLPGVQGQ KGREGPPGRDGQPGLDGFPGTPGQKGERGDKGDRGEAGRDGAGLPGPPGPPGPPGQIFYQ PSDN------FDAAFGRAGPQGGPGLPGQAGFPGPVGP---------------------- -------------------KGDTGNPGLPGL-GVKGEKGEPGL-----IIGPDGNPLYLG GLTGQKGDIGPQGPAGPM---------------------------GPQGPPGLKGEIGMP GRPGRPGVNGYKGEKGEPSGGL-GHG--GVPGPPGPPGPPGPPGPPFA---IDRFNRYDD ISR---------NYP-VKGEKGERGD---PGFPGTA-----------------SDFDIYT LKNQWKGE---RGDPGVKGEKGEPG--AG--HDPQYGALQGPLGP------PGLPGPKGD SIMGPPGPQ-------GPPGSPGI-GYDGRPGPPGPPGPPGPPWSQ----TL-------- ------PE-SYKPN----------------------YPVSVPGPP--GPPGPPGHP---G H-------SS-----G---------V-MVLRSYDTLIATARSQEEGSLIYILDKADLYLR VRDGLRQVMLGEYNPFFR--DFDNEVAEAQPPPVVLYPHS----------PDHSQNNGAS QYSQGGSVIRPIETP--PPVERRYP-PQYEPRFPD-QQRPSQTDGRLINQPSDG------ --KYAVTPQRRPNPPVPGP-------VETSTLGLRLIALNTPQSGNM-KGIRGPDYLCFE QARAAGLRGTFRAFLSSKVQDLHTIVRHSDREKPPIVNLKNQVLFDSWQSIFGE-SVSKM RKNVPIYSFDGRDILRDSAWPEKMVW-HGSSKKGHRQTDQ-YCEAWRAGDQAVTGLASSL QSSHLLQQTPTSCSRACIVLCIENAMVSPSK----------------------------- -----
BMGE Cleaned alignment of selected proteins >sp|P39060|COIA1_HUMAN Collagen alpha-1(XVIII) chain OS=Homo sapiens OX=9606 GN=COL18A1 PE=1 SV=5 MAPYPCGCHILLLLFCCLAAARANLFNNEDTSHAATTPEPQGPLPVQPTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYTEPGATHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLSDGASGDSGSGLGDELLREETGAALKPRLPPPPVTTPPLAGEDSRSEEVEEQLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGPLGPA--PALQTVPGPQ---GPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQ---GPPGPPGPPGPPTISVPGPPGPPGPPGPPRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEASATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK- >sp|P39060-1|COIA1_HUMAN Isoform 2 of Collagen alpha-1(XVIII) chain OS=Homo sapiens OX=9606 GN=COL18A1 MAPYPCGCHILLLLFCCLAAARANLFNNEDTSHAATTPEPQGPLPVQPTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSPGAHTTEAGTLPAPTPSPPSLGRPWEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYTEPGATHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLSDGASGDSGSGLGDELLREETGAALKPRLPPPPVTTPPLAGEDSRSEEVEEQLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGPLGPA--PALQTVPGPQ---GPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQ---GPPGPPGPPGPPTISVPGPPGPPGPPGPPRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEASATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK- >sp|P39060-2|COIA1_HUMAN Isoform 3 of Collagen alpha-1(XVIII) chain OS=Homo sapiens OX=9606 GN=COL18A1 MAP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------RCPWPWPRRRRLLDVLEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAMVLLGVKLSGVQDGHQDISLLYTEPGATHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLSDGASGDSGSGLGDELLREETGAALKPRLPPPPVTTPPLAGEDSRSEEVEEQLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGPLGPA--PALQTVPGPQ---GPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQ---GPPGPPGPPGPPTISVPGPPGPPGPPGPPRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVQNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHSHRDFQPVLHLVALNSPLSGGMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEASATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK- >NP_034059.2 collagen alpha-1(XVIII) chain isoform 2 precursor [Mus musculus] MAPR------------------------------------------------------------------------------------------------HLLDV---LTSLVLL---------------------------------------------------------------------------EEVGLLQLLGDPLPEKISQIDDPHVGPAYIFGPDSNSGQVAQYHFPKLFFRDFSLLFHVRPATEAAGVLFAITDAAQVVVSLGVKLSEVRDGQQNISLLYTEPGATQTGASFRLPAFVGQWTHFALSVDGGSVALYVDCEEFQRVPFARASQGLELERGAGLFVGQAGTADPDKFQGMISELKVRKTPRVSPVHCLEDRASGDFGSGFEEKSHKEDT--SLLPGLPPPPVTSPPLAGEDPRTEETEEDIGAETLPGTGSSGAWDEAIQNPGRGLIKGGMKGQKGEPGAQGPPGPAGPQGPAGPVVQPNSQPVPGAQGPPGPQGPPGKDGTPGRDGEPGDPGEDGRPGDTGPQGFPGTPGDVGPKGEKGDPGIGPRGPP---GPPGPPGPSFRQDKLTFIDMEGSGFSGDIESLRGPRGFPGPPGPPGVPGLPGEPGRFGINGSYAPGPAGLPGVPGKEGPPGFPGPPGPPGPPGKEGPPGVAGQKGSVGDVGIPGPKGSKGDLGPIGMPGKSGLAGSPGPVPGPPGPPGPPGPGFAAGFDDMEGSGIPLWTTARSSDGLQGPPGSPGLKGDPGVAGLPGAKGEVGADGAQGIPGPPGREGAAGSPGPKGEKGMPGEKGNPGKDGVGRPGLPGPPGPPGPVIYVSSEDSTPGPEGKPGYAGFPGPAGPKGDLGSKGEQGLPGPKGEKGEPGTIFSPDGRALGHPQKGAKGEPGFRGPPGPYGRPGHKGEIGFPGRPGRPGTNGLKGEKGEPGDASLGFSMRGLPGPPGPPGPPGPPGMPINAFVESGRPGLPGQQGVQGPSGPKGDKGEVGPPGPPGQFIDLFHLEAEMKGDKGDRGDAGQKGERGEPGGGGFFSSSVPGPPGPPGYPGIPGPKGESIRGPPGPPGPQGPPGIGYEGRQ---GPPGPPGPPGPPTVSVPGPPGPPGPPGPPRIWATYQTMLDKIREVPEGWLIFVAEREELYVRVRNGFRKVLLEARTALPRGTGNEVAALQPPLVQLHEGSPYTRREYSYSTARPWRADDILANPPRLPDRQPYPGVPHHSSYVHLPPARPTLSLAHTHQDFQPVLHLVALNTPLSGGMRGIRGADFQCFQQARAVGLSGTFRAFLSSRLQDLYSIVRRADRGSVPIVNLKDEVLSPSWDSLFSGSQGQLQPGARIFSFDGRDVLRHPAWPQKSVWHGSDPSGRRLMESYCETWRTETGATGQASSLLSGRLLEQKAASCHNSYIVLCIENSFMTSFSK >XP_021334397.1 collagen type XVIII, alpha 1 isoform X3 [Danio rerio] MARRC-------------------------------------------------------------------------------------------------------LERFFCLV--------------------------------------------------------------------------SGVSLLQLIGDPPPNGVSKVFDQANSPGYVFGPSSNVGQSAAAHLPNPFYRDFSLIFNIKPTSSKPGVIFSITDPTQNIMYVGVKLSAVERGKQSIIFYYTEPDSSYEAARFSVSSMLNIWTRFSISVLNEQVSLYFNCDDPQVVNFERSPDDMDMDAGAGVFVGHASGADPDKFLGVIGDLRVSRDPGAAERHC-ATEASGDYGASGDG-PSPVQ------PTPPSRPIQRPPVISQ--RPPVISRE--ARGEKGSVSGGGSKGDKGVPGEKGMKG---GSKGDRGPPGPPGPPGPQGPSAEVEVGDGSVVQKVTGPRGPPGPQGPPGPPGPEGEPGDPGEDGKAGQVGPSGFPGNPGNPGPKGDKGDRGESQPGPRGPPGPPGPPGPSSGFDRPTFVDMEGSGF--DMDSVRAVPGLPGPPGPPGPPGPPGSASSGS-------GGFGPPGPPGQNGAPGQPGLS---GVPGADGKPGLPGPKGEKGDPGPVGEKGAKGSSGPPGTTGIGGPAGLPGPIIGLPGPPGPPGPSFNVGFDDMEGSGVHFSSV-RGPVGIPGPPGVPGPQGQP---GFPGLPGEKGSLGAQGNDGLPGADGFPGPQGPKGDKGERGDRGEPGRDGHGHPGQPGPPGPPGQIIYRYSEHGGTGAQGVPGQAGFPGPMGPKGDRGEPGLPGY-DIKGEKGEPGLILGPDGNPLYTGQKGERGISGPVGPPGPAGPPGAKGEFGMPGRPGRPGVNGYKGEKGEPSSGS-GYGY---PGPPGPPGPPGPPGPAVGRYEDYAR-------LYPATKGEKGDQGAPGIPGSPGFSFDIYSLKNEMKGE---RGESGLKGEKGEPGGG-FYDPRFQ---GPPGNPGPAGPKGDSIRGPPGPQGPPGTPGVGYDGRPGNPGPPGPPGPPGSPPLSIPGPPGPPGPPGIPTVLRSHDIMIATARRQTEGTLIYILDRNDLYLRVRDGVRQVMLGDYKPLYGELDNEVAAVQPPPVVHYSQDHTANNGAEQISPQPIDFPPNPQPDPRYPDPRYPPYTDRNPITPARRPIPPVNQPHAHTHTSGPGLHLIALNSPQVGNMRGIRGADFMCFQQARAVGMKGTFRAFLSSKLQDLYSIVRRSDRETLPIVNLKDQVLFSSWESLFSDSESRMKDNAPIYSFDGRDVLRDSAWPEKMIWHGSDGRGHRQTDNYCETWRAGDAVTGLASSLQAGQLLQQTSSSCSSSYIVLCIENSYMTQSKK >NP_445941.2 collagen alpha-1(XVIII) chain precursor [Rattus norvegicus] MAPR------------------------------------------------------------------------------------------------HLLDM---LTSLVLL---------------------------------------------------------------------------EDVGLLQLLGDPLPQKISQVEDPHVGLAYVFGPYSKSSQMAQYHFPKLFFRDFSLLFEVRPTTEAAGVLFAITDAAQVVVSLGVKLSEVRDGQQNISLLYTEPGATQTGASFRLPAFVGQWTHFALSVDGSSVALYVDCEEFQRVPFARSPHGLELERGAGLFVGQAGAADPDKFQGMISELRVRKTPRVSPVHCLDDRASGDFGSGLEENLHRQET--YLRPGLPPPPVTSPPLAGEDSRTEEKEEEKGADTLPVTDSSGVWDGDVQNPGGGLIKGGLKGQKGEPGAQGPPGPAGPQGPAGPAVQPSSQPVPGAQGPPGPQGPPGKDGIPGRDGEPGDPGEDGRPGDTGPQGFPGTPGDVGPKGEKGDPGIGPRGPP---GPPGPPGPSFRQDKLTFIDMEGSGFSGDLESLRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSYAPGPAGLPGVPGKEGPPGF---PGPPGPPGKEGPPGVAGQKGSVGDAGSPGPKGSKGDLGPIGMPGKSGLPGLPGPVPGPPGPPGPPGPGFAAGFDDMEGSGTPLWSTARSSDGLQ---------GDPGVTGPPGAKGEVGADGVQGIPGLPGREGVAGPPGPKGEKGTQGEKGNPGKDGVGRPGLPGPPGPPGPVIYVSNEDSTPGPEGKPGYAGFPGPAGPKGDLGSKGEQGLPGPKGEKGEPGSIFSPDGTALGQAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGTNGLKGEKGEPGEASLGFSMRGLPGPPGPPGPPGPPGVPVNAFVESGRPGLPGQQGVQGPPGPKGDKGEVGPPGPPGQFIDLFHLEAEMKGDKGDRGDAGRKGERGEPGGGGFFSSSVPGPPGPPGYPGIPGPKGESIRGPPGPPGPQGPPGIGYEGRQ---GPPGPPGPPGPPTVSVPGPPGPPGPPGPPRIWATYQTMLDKIREVPEGWLIFVAEREELYVRVRNGFRKVLLEARTALPHGTDNEVAALQPPLVQLHEGSSYTRREHSYPTARPWRADDILANPPRLPDRQPYPGVPHHSSHEHRPPAHPSPSPAHTHQDFHPVLHLVALNTPLSGGMRGIRGADFQCFQQARAVGLSGTFRAFLSSRLQDLYSIVRRADRSSVPIVNLKDEVLSPSWDTLFSGSQGQLHSGARIFSFDGRDVLRHPAWPQKSVWHGSDPSGRRLMESYCETWRTEAGVTGQASSLLSGRLLEQKAESCHNSYIVLCIENSFMTSFSK >XP_025007836.2 collagen alpha-1(XVIII) chain isoform X1 [Gallus gallus] MR----------------------------------------------------------------ALQAPR----------------------------------------WGQAPTSAPDPLCLR---------SQGARFPLPMALLH-LGLWLLLASCCFSSSDAQL---------------LDWIWTEVSLLELIGDPPPEEILKIYGPDNNPGYVFGPSANTGQVARYHLPSPFYRDFSLLFHIQPTTPRAGMLFAITDSTQSIIYVGVKLSDLQMGKQQIIFYYTEPGSSYAAATFTVPTLLNQWTRFAISVEEDEVILYLDCEEHERVRFERSPDEMELEEGSGLFVAQAGGADPDKYQGVIADLRLRGDPRAAEHQC-AE-ASGDFGSGAEDHPSGKDKGI---PGLLAVPVTSPPVVEQQAERTRVEERTGPKGEKGILGTGATKGEKGEKGELGIKGGSKGQKGEPGEPGPPGP---------LSRTDSMSLEQVTGPPGPTGPPGKDGAPGRDGEPGDPGEDGKPGEMGPQGFPGTPGESGQKGEKGDPGVGPRGPPGPPGPPGPPGRSSKQDGLTFIDMEGSGFGGDLETLRGPRGPPGPPGPPGVPGLPGEPGRFGMNSTDLPGP---PGLPGRDGTPGAPGPEGPLGPPGKDGMPGPPGPKGERGDPGAPGPKGSKGEAGPAGPPGETGLAGLPGPVPGPPGPPGPPGPGYEAGFGDMEGSGLPLATGSRGPSGPQGVPGLPGIKGEVGSLGQPGPPGPKGDAGVPGVDGRPGLEGFPGPQGPKGNRGSPGEKGERGQDGVGLPGPPGPPGPPGQVIYMSSEDALPGPEGRSGHAGFPGPVGPKGDPGSPGIQGAPGIKGEKGEPGVIISPDGTIVAANVKGQKGEPGLPGPMGPHGRAGMKGEIGFPGRPGRPGMNGLKGEKGDPVDISSVLSLRGPPGPPGPPGPPGPPGSVVNGFSDASR---PAFPGFHQFPGQKGEKGDVGAPGPPGQFYDLSRFSASLRGD---KGEAGPKGEKGEPGSSTLYGPSVTGPPGPQGYPGPPGPKGDSIVGPPGPPGPQGPPGIGYEGRQ---GPPGPPGPPGPPAISIPGPPGPPGPPGPPRTMPTYQAMLSAAHELPEGGLIFLADRQELYIRLRGGFRRVLLEEHTLVPSALDNEVYDKLPSIH--YGGAHPLRNHNPPPTARPWRGDEVVANQHHLPQPLL-----LNSYYIHRWP-DPAPVAAHVHQDFQPALHLVALNTPLSGGMRGIRGADFQCFQQARQVGLAGTFRAFLSSRLQDLYSIVRRADRTAVPIVNLRDEVLFSNWEALFTGSEAPLRAGARILSFDGRDILQDSAWPQKSIWHGSDAKGRRLPESYCEAWRTDEGTSGQASSLSSGKLLEQSASSCQHAFVVLCIENSFMTAAKK >XP_009439942.2 collagen alpha-1(XVIII) chain isoform X1 [Pan troglodytes] MAPYPCGCHILLLLFCCLAAARADLFSNEDTSHAATTPEPQGPLPVQPTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSLGAHTTEAGTLPAPTPSPPSLGRPWEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAVVLLGVKLSGVQDGHQDISLLYTEPGATHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSQGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLSDGASGDSGSGLGDELLREETGVALKPRLPPPPVTTPPLAGEDSRSEEIEEQLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGRAGPPGPLGPA--PALQPVPGPQ---GPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGDPGPAGARGESGLAGAPGPAPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSAAGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSQGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDSVPGPEGRPGFAGFPGPAGPKGNLGSKGEQGSPGPKGEKGEPGSIFSPDGGALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFSSSLPGPPGPPGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPGPPTISVPGPPGPPGPPGPPRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVRNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHTHRDFQPVLHLVALNSPLSGSMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRTAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEASATGQASSLLGGRLLGQSAVSCHHAYIVLCIENSFMTASK- >XP_024830782.1 collagen alpha-1(XVIII) chain isoform X1 [Bos taurus] MAPDPSSHHGLLLLACCLSAAQADLSGNSAWPIAAPASKPPDSSPVWPTTHVAPRDAPTDWWKVSASPTAPLGRPEVGQGQTPSTVSLDPKEENIAGVGAKILNVAQGIRSFVQLWDDTTPAESSAGAET------MDDLSTPGPSITPQDSGTTLQLSTTALSSPDTQRTEAGTLPMPTQPPPSPGRPWVEVGLQQLLGEPPPWQVAMVHDPDVGSAYEFGEDGSGGQAARRLLPGTFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTAARGGRQHMQLLYTEPGATRTAASFELPALDGRWTRLALSVDGAYARLFVDCKEVQGQPLAHSLHDLQLEPDARLFVAQAGGADPEKFQGLISELRLRRDPQVSPRQCQDDGASGDLGSGLVEEHLREELGAPLGPRLPAPPVTSPPLAGEDLRTEEVEESLGAQTLPSLGTVGTWDESVWSPGSSVKERGLKGQKGEPGAQGPPGPIGPQGPAGPAIDHEAQPVSGPQGPPGPPGPPGKDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGEKGDPGVGPRGPPGPQGPPGPPGPSFKPDRLTFIDMEGSGFGGDLESLRGPRGFPGPPGPPGVPGLPGEPGRFGMNSSDVPGPAGLPGVPGRDGPPGRPGPPGPPGTPGKDGQPGLTGQKGSLGEAGAPGPKGSKGDLGPVGAPGEHGLAGAPGPAPGPPGPPGPPGPGFAAGFDDMEGSGSPLWSTARGAEGLQGPPGTPGVKGDPGAVGPPGSKGEVGADGAPGLPGLPGREGAAGPQGPKGEKGTQGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDSVPGPEGRAGFAGFPGPAGPKGDLGAKGQQGIPGPKGEKGEPGTFFGPDGRALTPAQKGAKGEPGFRGPPGPYGRPGHKGEIGFPGRPGRPGMNGLKGEKGEPGDASVGFGMRGPAGPPGPPGPPGPPGTPVNAFVDSGRPGPPGLPGHQGPSGLKGDKGDVGPPGPPGQFFDLLQLGAEMKGEKGDRGAAGQKGERGEPGGGGFFGSGVPGPPGPPGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGPQGPPGPPGPPGPPGPPTISVPGPPGPPGPPGPPRVWATYQMLVDQVPQVPEGWLIYVADREELYVRVRNGFRKVLLEAHVPLPHGTDNEVAVLQPPLVQLHEGNPYPRREVPHPTARSWRADDILASPPRLPHPQPYPGAPHHGAYAHLRPVPPTASPSHTHHDFQPVLHLVALNSPQSGGLRGIRGADFQCFQQARAAGLAGTFRAFLSSRLQDLYSIVRRADRATLPVVNLRDEVLFPSWEALFSGSEGQLKPGARIFSFDGRDVLQHPTWPQKSVWHGSDPSGRRLTESYCETWRTDSAATGQASSLLAGRLLEQKAAGCHNAFIVLCIENSFMTSSSK >XP_010711461.1 collagen alpha-1(XVIII) chain isoform X1 [Meleagris gallopavo] M---------------------------------------------------------------------PRAADH----------------------------------RGWGPWAIPRPSPATPS---------AATPGDADPKCSTNGEGLALLGVSGNQSPSVPKLSGVDSPPAG---PPEFDLLTSEVSLLELIGDPPPEGIVKIYGHENRPGYVFGPSANTGQVARYHLPSPFYRDFSLLFHIQPTTPRAGVLFAITDSTQSIIYVGVKLSDLQMGKQQIIFYYTEPGSSYAAATFTVPTLLNQWANFAISVEEDEVILYLDCEEHERVRFERSPDEMELEEGAGLFVGQAGGADPDKYQGVIADLRLRGDPRAAEYHC-TE-ASGDFGSGAEDRPLGKDKGI---PGLLAVPVTSPPVVEQQAERTRVEERTGPKGEKGILGPGTAKGEKGEKGELGIKGGSKGQKGEPGEPGPPGP---------LSRTDGMSLEQVTGPPGPTGPPGKDGAPGRDGEPGDPGEDGKPGEMGPPGFPGTPGESGQKGEKGDPGVGPRGPPGPPGPPGPPGPSSKQDRLTFIDMEGSGFGGDLETLRGPRGPPGPPGPPGVPGLPGEPGRFGMNSTDLPGQ---PGLSGRDGTPGPPGPEGPLGPPGKDGMPGLPGPKGERGDPGAPGPKGSKGEAGPAGPPGETGLAGLPGPVPGPPGPPGPPGPGYEAGFGDMEGSGLPLATGSRGPSGPQGVPGLPGIKGEVGSLGQPGLPGPKGDAGVPGVDGRPGLEGFPGPQGPKGNRGSPGEKGERGQDGVGLPGPPGPPGPPGQVIYISSEDALPGPEGRPGLAGFPGPVGPKGDPGSPGIQGAPGMKGEKGEPGVIISPDGTIVAANMKGQKGEPGLQGPMGPHGRAGMKGEIGFPGRPGRPGMNGLKGEKGDPVDISGMLSLRGPPGPPGPPGPPGPPSSVVNGFSDASR---PAFPGFHQFTGQKGEKGDVGAPGPPGQFYDLSRFSANLRGD---KGEAGPKGEKGEPGGSTLYGPGVTGPPGPQGYPGPPGPKGDSIVGPPGPPGPQGPPGIGYEGRQ---GPPGPPGPPGPPAISIPGPPGPPGPPGPPRAMPTYQAMLSAAHELPEGGLIFVTDRQELYVRLRGGFRRVLLEEHTLIPSALDNEVYDKLPSIH--YGGAHPLRNHSPPPTARPWRGDEVVANQHRLPQPLL-----LNSYYIHRWP-DPASVAAHVHRDFQPALHLVALNTPLSGGMRGIRGADFQCFQQARQVGLAGTFRAFLSSRLQDLYSIVRRADRTSVPIVNLRDEVLFSNWEALFTGSEAPLRAGARILSFDGRDILQDSAWPRKSIWHGSDVKGRRLPESYCEAWRTDEGTSGQASSLSSGKLLEQSASSCQHAFVVLCIENSFMTAAKK >XP_020927188.1 collagen alpha-1(XVIII) chain isoform X1 [Sus scrofa] MAPDPSGLGLLLLLACCLAATWADPFSEATMPKATPASVPQAPAPVPPGPEQRPETPPRTWARAPLSPRPPREP--GPQGGEHRGCGSQDPER---GSGHPALHPAVG---------HHAPRE-LRRRGDASPPTPTDPLTTPGPSSTLWESGTTLWLSSGAPSSPDTQRTEAGTQPLPTQPPPSPGGPLVEVGLQQMLGEPLPRQVALVHDPDVGPAYEFDGISGVGQAALSLVPRTFFHDFSLLMRVRPASAGAGVLFAVTDAAQAVVLVGVKLAAARGGQQQVQLLYTEPGATRTAASFTLPALHGRWTHLALSVDGAHVALFVDCEEVQLEPLSRSLRALQLEPDARLFVAQAGRADPDKFQGMISELRVRGDPQVSPLQCRDNEASGDLGSGLAEERLGAPSGAPLRPRLPAPPVTSPPLAGEDSRTEEVEEAPGAQTLPGSGAVTTWDGSSWSPGDSLEERGLKGQE-EPGAQGLPGQASPQGPTGPVMRPEAQPVPGPQGPPGPPGPPGKDGAPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGEKGDPGVGPRGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLESLRGPRGFPGPPGPPGVPGLPGEPGRFGMNSSDVPGPAGLPGVPGRDGAPGPPGPPGPPGFPGRDGQAGQTGQKGSVGEVGAPGPKGSKGDPGPVGAPGNPGLAGVPGPAPGPPGPPGPPGPGLAAGFDDMEGSGGPFWWAAQGADRPQAPPGPPGVKGDPGAVGPAGTKGEVGADGAPGLPGLPGREGAAGPQGPKGEKGTRGDKGDPGKDGVGQPGLPGPPGPPGPVVYVS--DSVPGPEGRTGFAGFPGPAGPKGDLGSKGQPGLPGPKGEKGEPGTVFSPDGRPLTPAQKGAKGEPGFRGPPGPYGRPGHKGEIGFPGRPGRPGMNGLKGEKGEPGDASVGFSLRGPPGPPGPPGPPGPAGTPVNAFVESGRPGPPGLPGYQGPPGPKGDKGEMGPPGPPGQFFDLLHMEAELKGEKGDRGEAGQKGERGEPGGGGFFGSSVPGPPGPPGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPGPPTISVPGPPGPPGPPGPPRVWATYQTMLDKVPEVPEGWLMFVAEREELYVRVRNGFRKVLLEARTPLPRGTDNEVAALQPPVVQLHEGNPYPRREPPQPTARAWRGDDIRASPPRLPVAQPYPGAPHHGAYVHPRPVHPTGSPAHTHHDFQPVLHLVALNSPQSGGLRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLRDEVLFPSWEALFSGSEGQLKPGARIFSFDGRDVLQHPAWPQKSVWHGSDPSGRRLTESYCETWRTEATATGQASSLLAGRLLEQKAAGCHHAFIVLCIENSFMTSASK >XP_038299617.1 collagen alpha-1(XVIII) chain isoform X1 [Canis lupus familiaris] MARHPGRLLLLLLLTCCPAAAQVDLSTRTAGPTAEPVSEAPGSPHVQPRTPVTPQPGPTEQGNAPASPEPPLRGLETDEHAASPPAGPDEKEENIAGVGAKILNVAQGIRSFVQLWDDTTRPESSSTAGTPAPVTPTSPLALPGPSRPPPENGTALW-----LGSTDAPRVEASTLPAPTRLPPSLDRPRSEVGLLQLLGEPPPQQVTQVDDPDVGPAFVFGPDANSGQVARYHVPSPFFRDFSLLMHVRPATEGPGVLFAITDAAQAVVSVGVKLSGVRDGQQHVQLLYTEPGATRTAASFRLPAFTGQWTRLALSVDGATVALFVDCELFQRVPLERSPGGLQLEPGAGLFVAQAGGADPDKFQGMIAELRVRGDPHVSPLHCLSGGVSGDFGSGLED---REPSGLLPKAELPAPPVTSPPLTGEDSRMEEIEEELGARTLPGSATVTA--ESAQRLGGSLQE----------------------APTGPAAHPEAWPGPGPQGPPGPPGPPGKDGTPGRDGEPGDPGEDGRPGDPGPQGFPGTPGDVGPKGEKGDPGVGPRGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLESLRGPRGFPGPPGPPGVPGLPGEPGRFGMNSSDVPGPAGLPGVPGRDGPPGLPGAPGPPGPPGKEGGPGKPGPKGSPGDAGAPGPKGSKGDPGPIGVPGESGLAGPPGPAPGPPGPPGPPGPGLAAGFVDMEGSGEPFWSTAHGASGPQGPPGLPGVKGDPGIVGPPGAKGEVGADGPPGFPGLPGREGTAGAQGPKGEKGTQGEKGEPGRDGVGQPGLPGPPGPPGPVVYVSEQEGVPGPEGRPGHAGFPGPAGPKGDLGSKGQRGPPGPKGEKGEPGPAFSPDGSMLAPAQKGAKGEPGFRGPPGPYGRPGHKGEIGFPGRPGRPGMNGLKGEKGEPGQASAGFGMTGPPGPPGPPGPPGPPGTPVNAFMEPGHPGPPGLPGHQGPSGPKGDKGDVGPPGPPGQFFDLLQLGAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSVPGPPGPPGYPGIPGPKGESVQGHPGPPGPQGPPGIGHEGRRGPPGPPGPPGPPGPPTISVPGPPGPPGPPGPPRIWATYQTMLDKVPDVPEGWLMFVAEREELYVRVRNGFRKVLLEARVPLPRGTDNEVAALQPPVVQLHEGNPYPRREPTHATARPWRADDILASPPRLLDPQPYPGAPHHGSYVHFQPARPTGGPTHTHQDFQPVLHLVALNSPQPGGMRGIRGADFQCFQQARAAGLAGTFRAFLSSRLQDLYSIVRRADRTGVPVVNLRDEVLFPSWEALFSGSEGQLKPGARIFSFDGRDVLQHPAWPRKSVWHGSDPSGRRLTDSYCETWRTEAAATGQASSLLAGRLLEQEAASCRHAFVVLCIENSVMTSFSK >XP_034803833.1 collagen alpha-1(XVIII) chain isoform X1 [Pan paniscus] MAPYPCGCHILLLLFCCLAAARADLFSNEDTSHTATTPEPQGPLPVQPTTHVTPRNGSTEPATAPGSPEPPSELLEDGQDTPTSAESPDAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSLGAHTTEAGTLPAPTPSPPSLGRPWEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAVVLLGVKLSGVQDGHQDISLLYTEPGATHTAASFRLPAFVGQWTHLALSVAGGFVALYVDCEEFQRMPLARSSRGLELEPGAGLFVAQAGGADPDKFQGVIAELKVRRDPQVSPMHCLSDGASGDSGSGLGDELLREETGAALKPRLPPPPVTTPPLAGEDSRSEEIEEQLGAQTLPGSDSVSTWDGSVRTPGGRVKEGGLKGQKGEPGVPGPPGQAGPPGPLGPA--PALQPVPGPQ---GPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGIGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGRFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGDPGPAGARGESGLAGAPGPAPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSAAGPQGPPGLPGLKGDPGVPGLPGAKGEVGADGVPGFPGLPGREGIAGPQGPKGDRGSQGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDSVPGPEGRPGFAGFPGPAGPKGNLGSKGERGSPGPKGEKGEPGSIFSPDGSALGPAQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFSSSLPGPPGPPGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPGPPTISVPGPPGPPGPPGPPRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVRNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHTHRDFQPVLHLVALNSPLSGSMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRTAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEASATGQASSLLGGRLLGQSAVSCHHAYIVLCIENSFMTASK- >XP_023094382.1 collagen alpha-1(XVIII) chain isoform X1 [Felis catus] MARDPGGLLLLLLLTYGLAAAQVDLAPRTAGPTVEPASAPPRSPHVQPTAHVAPRDDPTEQGRAPASPEPPPGRLETGRDQASSTAGPDTKEENIAGVGAKILNVAQGIRSFVQLWDGTTPSQSSTGAETPAPGTPTAPLTLPGPSGAPPEDGTTLWLSSRALTSPDTQRTEAGTLPVPTQLPPSPGRPRTEVGLLQLLGEPPPQQVAQVDDPDVGPAFVFGPDANSGQVARYHFPSPFFRDFSLLFHVRPATEGAGVLFAITDAAQAVVSVGVKLSAVRDGQQHIQLLYTEPGATRTAASFRLPAFTGQWTRFALSVDGATVALFVDCELFQRVPLVRSPRALELEPGAGLFVAQAGGADPSKFQGRIAELRVRGDPRVSPLHCLSGGVSGDFGSGLEEELLREQSGLSPKPSLPAPPVTSPPLAGEDARTEEIEEELGAWTLPGSDTVTAW--SVRSPGGGPEE----------------------GPAGSAVHPDAQPVPGPQGPPGPPGPPGKDGAPGKDGEPGDPGEDGKPGDPGPQGFPGTPGDMGPKGEKGDPGVGPRGPPGPQGPPGPPGPSFRHDRLTFIDMEGSGFGGDLESLRGPRGFPGPPGPPGVPGLPGEPGRFGMNSSDVPGPAGLPGVPGRDGAPGLPGAPGPPGPPGRDGGPGKTGQKGSPGEAGAPGPKGSKGDPGPTGAPGETGLAGAPGPAPGPPGPPGPPGPGLAAGFEDMDGSGGPFWATAHGASGPQGPPGLPGVKGDPGIAGPPGAKGEVGADGPPGFPGLPGREGTAGAQGPKGEKGTQGEKGDPGRDGVGQPGLPGPPGPPGPVVYVSEQDGVPGPEGRPGYAGFPGPAGPKGDLGSKGQRGPPGPKGEKGEPGPVFSPDGGTLGPAQKGAKGEPGFRGPPGPYGRPGHKGEIGFPGRPGRPGMNGLKGEKGEPGHASVGFGVRGPPGPPGPPGPPGPPGTPVNAFMESGRPGPPGLPGYQGPPGPKGDKGEVGPPGPPGQFLDLLQLEAEMKGEKGDRGDPGQKGERGEPGGGGFFGSSVPGPPGPPGYPGIPGPKGESIRGQPGPPGPQGPPGIGHEGRQGPPGPPGPPGPPGPPTISVPGPPGPPGPPGPPRIWATYQTMLDKVPEVPEGWLIFVAETEELYVRVRNGFRKVLLEARTPLPRGTDNEVAALQPPLVQLHEGHPYPRRELTHSTARPWRADDILAGPPRLPDPRPYPGAPQNGPYLHVQPARPTGGPTHAHQDFQPVLHLVALNSPQPGGMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRTGVPIVNLRDEVLFPSWEALFSGSEGQLKPGARVFSFDGRDVLQHPAWPQKSVWHGSDPSGRRLTDSYCETWRTEDAAAGQASSLLAGRLLAQKAASCRNAFIVLCIENSFMTSSSK >XP_027816975.1 collagen alpha-1(XVIII) chain isoform X3 [Ovis aries] MAPDPSSHHSLLLLACCLSAAQAQLSGNSAWPTAAPASKTPDSSPVWPTTHVAPRDASTDWWKVPASPTDPLGRPEAGQGQTPSSSSPDLKEENIAGVGAKILNVAQGIRSFVQLWDDTTPAESSARAGMLAPATPTDTLSTPGPSSTPQDSGTTLQPSTKALSSPDTQMTEAGALPVPTQPPPSPGRPWVEVGLQQLLGEPPPWQVAVVHDPAVGPAYEFGEDGSGGQAARSLLPSAFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTAARGGRQHLQLLYTEPGATRTAASFELPALDGRWTRLALSVDGAYARLFVDCEEVQGQPLAHSLHDLQLEPDARLFVAQAGGADPEKFQGLISELRLRRDPRVSPRQCQDDGASGDLGSGLMEEHPREELGTPLGPRLPAPPVTSPPLAGEDLRTEEVEESLGAQTLPSLGTVGTWDESVWSPGSSVKEQGLKGQKGEPGAQGPPGPIGPQGPAGPAIDHEAQPVSGPQGPPGPPGPPGKDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGEKGDPGVGPRGPPGPQGPPGPPGPSFKPDRLTFIDMEGSGFGGDLESLRGPRGFPGPPGPPGVPGLPGEPGRFGMNSSDVPGPAGLPGVPGRDGLPGVPGPPGPPGIPGKDGQPGLTGQKGSLGEAGAPGPKGSKGDPGPIGAPGEHGLAGAPGPAPGPPGPPGPPGPGFAAGFDDMEGSGSPFWSTARGADGLQGPPGTPGVKGDPGAVGPPGSKGEVGADGAPGFPGLPGREGAAGPQGPKGEKGTQGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDSVPGPEGRAGFAGFPGPAGPKGDLGAKGQQGIPGPKGEKGEPGTFFGPDGRALTPAQKGAKGEPGFRGPPGPYGRPGHKGEIGFPGRPGRPGMNGLKGEKGEPGDASVGFGMRGPPGPPGPPGPPGPPGTPVNAFVDSGRPGPPGLPGHQGPSGPKGDKGDVGPPGPRGQFFDLLQLGAEMKGQKGERGAAGQKGERGEPGGGGFFGSGVPGPPGPPGYPGIPGPKGESVRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPGPPTISVPGPPGPPGPPGPPRVWATYQMLVDQVPQVPEGWLIYVADREELYVRVRNGFRKVLLEAHMPLPHGTDNEVAVLQPPLVQLHEGNPYPRREAPHPTARSWRADDILASPPRLPHPQPYPGAPHHGTYAHLRPVTSTASPSHTHHDFQPVLHLVALNSPQSGGLRGIRGADFQCFQQARAAGLAGTFRAFLSSRLQDLYSIVRRADRGSLPVVNLRDEVLFPSWEALFLGSQGWLKPSARIFSFDGRDVLQHPAWPQKSVWHGSDTSGRRLTESYCETWRTDSAATGQASSLLSGRLLEQKAAGCHNAFIVLCIENSFMTSSSK >XP_030860999.1 collagen alpha-1(XVIII) chain [Gorilla gorilla gorilla] MAPYPCGCHILLLLFCCLAAARANLFNNEDTSHAATTPEPQGPLPVQPTTHVTPQNGSTEPATAPGSPEPPSELLEDSQDTPTSAESLDAPEENIAGVGAEILNVAKGIRSFVQLWNDTVPTESLARAETLVLETPVGPLALAGPSSTPQENGTTLWPSRGIPSSLGAHTTKAGTLPAPTPSPPSLGRPW-------------------------------------------------------------------------------------------------------------------------------------------------------------------VGRAG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PGVGLR-----QAPCGK-------------------------------------------------------------------VSGNDQC-----------------------------------------------------------------------------------------------------------------------------------------------------------------------PAVPTPCAPP-------------------------------------------------------------------------------------------------QGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSSLPGPPGPPGYPGIPGPKGESIRGQPGPHGPQGPPGIGYEGRQGPPGPPGPPGPPGPPTISVPGPPGPPGPPGPPRLWATRQAMLGQVHEVPEGWLLFVAEQEELYVRVRNGFRKVQLEARTPLPRGTDNEVAALQPPMVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHTHRDFQPVLHLVALNSPLSGSMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRAALPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDILRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEASATGQASSLLGGRLLGQSAASCHHAYIVLCIENSFMTASK- >XP_013226958.1 LOW QUALITY PROTEIN: collagen alpha-1(XVIII) chain [Columba livia] MALAPCCLGFLLLLACCFSSSETQLTGSTAAPSKGTT-APELASVAAPTDITTPQHWEQDPSTAQPSIAPPRSTSPTGTTEDPTTKNPQTEDLQLLGTGPAVMGIPVSLQRPVGPWPGSAPFPFSPGDDPHEQVVLGASPAPPNLQRGTGRWGLVLAGMNGSRSPPLPNRNSVDPPLADNSRPLGFDLLTAEVSLLELIGDPPPEEILKIYGPDNNPGYVFGPNANTGQVARYHLPSPFYRDFSLLFHIQPTSPRAGVLFAITDSSQSIIYMGVKLSELQAGKQQIIFYYTEPGSSNAAATFTVPTLLNQWTRFAISVEEDEVILYLDCEEHERTHFERSPDEMELEDGSGLFVAQAGGADPDKYQGVIADLKLRGDPRAAERQC-TEEVSGDFGSGAEGQPSGKDRGV---PGLVAVPVTSPPVAAQQAERTRAEETTGPKGEKGIVGTGSIKGEKGEKGEVGIKGGSKGQKGEPGDPGSPRT---------LSRADGSVVEQITGPP---GPPGKDGAPGRDGEPGDPGEDGKPGAMGPQGFPGMPGEPGLKGEKGDPGVGPRGPPGPPGPPGPPGPSSKHDKLTFIDMEGSGFGGDLESLQGPRGPPGPPGPPGVPGLPGEPGRFGMNQTDLPGP---PGLPGRDGTPGSPGPAGPQGPSGRDGAPGQPGPKGERGDPGAPGPKGSKGETGPAGAPGETGLAGLPGPMPGPPGPPGPPGPGYEAGFSDMEGSGLPFAASSPGPEGPQGVPGLPGMKGEVGSPGQPGLPGPKGDAGVPGVDGRPGLEGFPGPQGPKGDRGSPGEKGERGQDGVGLPGPPGPPGPPGQVITVSSEDALPGPEGRPGHAGFPGPLGPKGDQGPSGPQGPPGLKGEKGEPGVIISPDGTVVTAKVKGEKGEPGLRGPVGPPGRAGMKGEIGFPGRPGRPGMNGLKGEKGDPADVSSVLGLRGPPGPPGPPGPPGPPGSVVNAFSDSGRPVLPAFPGFHQFPGQKGEKGDTGAPGPPGHFYDLSHFGASLRGD---KGDAGPKGEKGEPGSTPLYGPSVPGPPGPQGYPGLPGPKGDSIVGPPGPPGPQGPPGIGYEGRQ---GPPGPPGPPGPPAISIPGPPGPPGPPGPPRPLPTYQAMLSAAHELPEGSLVFLTDRQELYVRLRGGFRRVLLEEHTLIPSALVSSLSSIHPSIQPSISNHPSISNHSPPPTARPWRGDEVVANQHRLPEPLLH----LNSYYIHRRP-DPAPVAAYVHQDFQPALHLVALNTPLSGSMRGIRGADFQCFQQARQVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLRDEVLFSNWEALFTGSGAPLRAGARILSFDGRDVLRDAGWPQKSVWHGSDAKGRRLPESYCE----XQPATGQASSLGSGKLLEQVASSCQHNFIVLCIENSFMTAAKK >XP_017907685.1 PREDICTED: collagen alpha-1(XVIII) chain isoform X1 [Capra hircus] MAPDPSSHHSLLLLACCLSAAQAQLSGNSAWPTAPPASKTSDSSPVWPTTHVAPRDASTDWWKVPASPTDPLGRPEAGQGQTPSSSSPDLKEENIAGVGAKILNVAQGIRSFVQLWDDTTPAESSARAGMLAPATPTDTLSTPGPSSTPQDSGTTLQSSTKALSSPDTQMTKAGALPVPTQPPPSPGRPWVEVGLQQLLGEPPPWQVAVVHDPAVGPAYEFGEDGSGGQAARSLLPSTFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTAARGGRQHLQLLYTEPGATRSAASFQLPALDGRWTRLALSVDGAYARLFVDCKEVQGQPLAHSLHDLQLEPDARLFVAQAGGADPEKFQGLISELRLRRDPRVSPRQCQDDGASGDLGSGLMEEHPREELGTPLGPRLPAPPVTSPPLAGEDLRTEEVEESLGAQTLPSLGTVGTWDESVWSPGSSVKEQGLKGQKGEPGAQGPPGPIGPQGPAGPAIDHEAQPVSGPQGPPGPPGPPGKDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGEKGDPGVGPRGPPGPQGPPGPPGPSFKPDRLTFIDMEGSGFGGDLESLRGPRGFPGPPGPPGVPGLPGEPGRFGMNSSDVPGPAGLPGVPGRDGLPGLPGPPGPPGIPGKDGQPGLTGQKGSLGEAGAPGPKGSKGDPGPIGAPGEHGLAGAPGPAPGPPGPPGPPGPGFAAGFDDMEGSGSPFWSTARGADGLQGPPGTPGVKGDPGAVGPPGSKGEVGADGAPGFPGLPGREGAAGPQGPKGEKGTQGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDSVPGPEGRAGFAGFPGPAGPKGDLGAKGQQGIPGPKGEKGEPGTFFSPDGRALTPVQKGAKGEPGFRGPPGPYGRPGHKGEIGFPGRPGRPGMNGLKGEKGEPGDASVGFGMRGPPGPPGPPGPPGPPGTPVNAFVDSGRPGPPGLPGHQGPSGPKGDKGDVGPPGPRGQFFDLLQLGAEMKGQKGERGAAGQKGERGEPGGGGFFGSGVPGPPGPPGYPGIPGPKGESVRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPGPPTISVPGPPGPPGPPGPPRVWATYQMLVDQVPQVPEGWLIYVADREELYVRVRNGFRKVLLEAHTPLPHGTDNEVAVLQPPVVQLHEGNPYPRREAPHPTARSWRADDILASPPRLPHPQPYPGAPHHGAYAHFRPVTSTASPSHTHHDFQPVLHLVALNSPQSGGLRGIRGADFQCFQQARAAGLAGTFRAFLSSRLQDLYSIVRRADRGSLPVVNLRDEVLFPSWEALFLGSEGWLKPGARIFSFDGRDVLQHPAWPQKSVWHGSDTSGRRLTESYCETWRTDSAATGQASSLLSGRLLEQKAAGCHNAFIVLCIENSFMTSSSK >XP_006022141.1 collagen alpha-1(XVIII) chain isoform X2 [Alligator sinensis] MAPAKPSLCLLLLLTCCFSLSEAQLEARTVPPEENST------------SLTSP---------AASTLHAPLQTTATLKRQEPPTAAPSDKEENIAGVGAEILTVAEGIRSLVQLWDVTKGTEGTEELTT------AAPFTAAHPSLSATSLVTGPAGIENMTADSTGGA--------------------TEVGLLQLIGDPPPEQITKIYGPDNNPGYVFGPDANTGQVARYHLPSPFYRDFSLLFHIQPTTNKAGVLFAITDSSQAVIYIGVKLSDAKEGKQHIIFYYTEPGSSYAAATFTVSSLLNQWTRFAVSVEDEEVVLFLDCEEYDRIRFERSPDEMELEDGSGLFVGQAGGADPDKYQGVIADLKIKNDPHAAVLQC-TEEMSGDFGSGVEEHSSGKERGIPTVSGLPPPPVTSPPIAGLQTEHIKAEETVGQKGEKGVPSTGGVKGEKGEKGELGVKGGSKGQKGEPGAPGDPGPPGPPGPSGTILQQDGSVVEHVTGPPGPPGLPGKDGFPGKDGEPGDPGEDGKPGDTGPQGFPGTPGEPGLKGEKGDPGVGSPGPPGPPGPPGIPGLSSKQDKLTFIDMEGSGFAGDLESLRGPRGPPGPPGPPGVPGLPGEPGRFGMNHTAIPGP---PGLPGKDGSPGLQGPPGPPGPPGREGLPGQPGFRGEKGDPGAPGPKGSKGETGPQGSPGETGLAGLPGPI-GQPGPPGPPGPGYEAGFGDMEGSGIPIVSSVRGPEGPQGPPGLPGLKGDIGSSGQPGVPGQKGDPGTPGTNGQPGLEGFPGPQGPKGDQGSPGVKGERGQDGVGLPGPPGPPGPPGEIVYASN--VLPGPEGRPGHAGFPGPVGPKGEAGSPGLQGFPGMKGEKGEPGVIIGPDGTVTALDTKGEKGEPGLRGPVGPHGRPGQKGEIGFPGRPGRPGMNGLKGEKGDPADPSGGFSLPGLPGPPGPPGPPGSPGSIVNAFTESGPPGPPGLPGYQGVPGHKGEKGDTGAPGPPGQFYDLSRFGAAFRGEKGEQGDSGLKGEKGEPGGGTLYGPGVPGLPGPQGYPGLPGPKGDSIVGPPGPPGPQGPPGIGYEGRQ---GPPGPPGPPGPPT-NVVGPPGPPGPPGPPKILPSYQAMLSTAHEVPEGWLVFIVDREELYVRVRNGFRRILLEDHTVISSALDNEVYDKPPSIH-FAHGSHPHRDYNTYATVRPWGGDDIIANHHRLPKPSIHQGAQLHDFYPNRRP-EDTPSAMHTHHDFQPALHLVALNTPLSGSMRGIRGADFQCFQQAREVGLTGTFRAFLSSRLQDLYSIVRRADRSSVPIVNLRDEVLFNNWESLFSGTEAQLRAGAHILSFNGKDILRDSTWPQKSVWHGSDSRGRRLTENYCETWRTDSVVTGQASSLSSGKLLEQKASSCQNAFVVLCIENSFMTSSKK >XP_019347546.1 PREDICTED: collagen alpha-1(XVIII) chain isoform X1 [Alligator mississippiensis] MHDEIPA---------VAGSLDNQLNSNHSVSHGNTT---------------------------------P-----------------------------HILKNADSSQSMQSIEP------------------------------SDKQFGKAVADLNRSHSDSVSNANFVDFFPANNSDSLGFDLLTTEVGLLQLIGDPPPEQITKIYGPDNNPGYVFGPDANTGQVARYHLPSPFYRDFSLLFHIQPTTNKAGVLFAITDSSQAVIYIGVKLSDAKEGKQHIIFYYTEPGSSYAAATFTVSSLLNQWTRFAVSVEDEEVVLFLDCEEYDRIRFERSPDEMELEDGSGLFVGQAGGADPDKYQGVIADLKIKNDPHAAVLQC-TEEMSGDFGSGVEEHSSGKERGIPTVSGLPPPPVTSPPIAGLQTEHIKAEETVGQKGEKGVPSTGGVKGEKGEKGELGVKGGSKGQKGEPGAPGDPGPPGPPGPSGTILQQDGSVVEHVTGPPGPPGLPGKDGLPGKDGEPGDPGEDGKPGDTGPQGFPGTPGEPGLKGEKGDPGVGSPGPPGPPGPPGIPGLSSKQDKLTFIDMEGSGFAGDLESLRGPRGPPGPPGPPGVPGLPGEPGRFGMNHTAIPGP---PGLPGKDGSPGLQGPSGPPGPPGREGLPGQPGFRGEKGDPGAPGPKGSKGETGPQGSPGETGLAGLPGPI-GQPGPPGPPGPGYEAGFGDMEGSGIPIVSSVRGPEGPQGPPGLPGLKGDIGSLGQPGVPGQKGDPGTPGTNGQPGLEGFPGPQGPKGDQGSPGVKGERGQDGVGLPGPPGPPGPPGEIVYASN--VLPGPEGRPGHAGFPGPVGPKGEAGSPGLQGFPGLKGEKGEPGVIIGPDGTVTALDTKGEKGEPGLRGPVGPHGRPGQKGEIGFPGRPGRPGMNGLKGEKGDPADPSGGFSVPGLPGPPGPPGPPGSPGSIVNAFTESGPPGPPGLPGYQGVPGHKGEKGDTGAPGPPGQFYDLSRFGAAFRGEKGEQGDSGLKGEKGEPGGGTLYGPGVPGLPGPQGYPGLPGPKGDSIVGPPGPPGPQGPPGIGYEGRQ---GPPGPPGPPGPPT-NVVGPPGPPGPPGPPKILPSYQAMLSTAHEVPEGWLVFIVDREELYVRVRNGFRRILLEDHTVISSALDNEVYDKPPSIH-FARGSHPHRDYNTYATVRPWGGDDIIANHHRLPKPSIHQGAQLHDFYPNRRP-EDTPSAMHTHHDFQPALHLVALNTPLSGSMRGIRGADFQCFQQAREVGLTGTFRAFLSSRLQDLYSIVRRADRSSVPIVNLRDEVLFNNWESLFSGTEAQLRAATHILSFNGKDILRDSTWPQKSVWHGSDSKGRRLTENYCETWRTDSVVTGQASSLSSGKLLEQKASSCQNAFIVLCIENSFMTSSKK >XP_020730828.1 collagen alpha-1(XVIII) chain [Odocoileus virginianus texanus] MAPDPSSHHGLLLFACCLSAAQADLPGNSAQPTAAPASKPRGSSPVWPTTHMAPRDAPTDWWKDSASPTAPLGRLEAGQGQSPSTASLDLKEENIAGVGAKILNVAQGIRSFVQLWDDTTPAESSGRAGTPAPATPTDPLSTPGPSSTPQDSGTTLQPSTGALSSPDTQRTEASTLPVPTQLPPSLGRPWVEVGLQQLLGEPPPWQVAVVHDPDVGPAYEFGEDGSGGQAARRLLPSAFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTAARGGRQHVQLLYTEPGATGTAASFELPALDGRWTRLALSVDGAYARLFVDCQEVQGQPLAQSLHDLHLEPDARLFVAQAGGADPEKFQGLISELRLRRDPRVSPRHCQDDGASGDLGSGLVEEHLREELGASLGPRLPAPPVTSPPLAGEDLRTEEVEESLGAQTFPSLGTVSTWDESVWKPGSSMKERGLKGQKGEPGAQGPPGPIGPQGPAGPAIDHKGQPVSGPQGPPGPPGPPGKDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGEKGDPGVGPRGPPGPQGPPGPPGPSFKPDRLTFIDMEGSGFGGDLESLRGPRGFPGPPGPPGVPGLPGEPGRFGMNSSDVPGPAGLPGVPGRDGPPGLPGPPGPPGTPGKDGQPGLTGQKGSLGEAGAPGPKGSKGDPGPIGAPGEHGLAGAPGPAPGPPGPPGPPGPGFAAGFDDMEGSGNVFWSTARGADGLQGPPGTPGVKGDPGAVGPPGSKGEVGADGSPGLPGLPGREGAAGPQGPKGEKGTQGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDSVPGPEGRAGFAGFPGPAGPKGDLGAKGQQGIPGPKGEKGEPGTFFGPDGRTLTPAQKGAKGEPGFRGPPGPYGRPGHKGEIGFPGRPGRPGMNGLKGEKGEPGDASVGFGMRGPPGPPGPPGPPGPPGTPVNAFVDSGRPGPPGLPGHQGPSGPKGDKGDVGPPGPPGQFFDLLQLGAEIKGEKGDRGAAGQKGERGEPGGGGFFGSGVPGPPGPPGYPGIPGPKGESIRGQPGPPGPQGPPGTGYEGRQGPPGPPGPPGPPGPPTISVPGPPGPPGPPGPPRVWATYQMLVEQVLQVPEGWLIYVADREELYVRVRNGFRKVL-----------DNEVAVLQPPLVQLHEGNPYPRREAPHPTARSWRADDILASPPRLPHPQPYPGAPHHGAYAHLRPVPPTASPSHTHHDFQPVLHLVALNSPQSGGLRGIRGADFQCFQQARAAGLAGTFRAFLSSRLQDLYSIVRRADRATLPVVNLR--VCARPCLGLTSGDSCPRLRGALV----AHQLGEVAGSPQAVMLCGSHPRTRALHRAFCGSFPEQNAF--------------------------------------- >XP_040213558.1 collagen alpha-1(XVIII) chain isoform X1 [Rana temporaria] MARARLCLAVLLLVVTLPALSQAQFTTTTAAPNSSATSSPEGSLPAAVTPATSPSSQPAATASLSAGVSSPSNQTSSGSDAQPPTSAPESEDKNIAGVGAEILNVAENIRNFMNVWEEKAKDLMTSTDNPPAEQGLGELINMTLPT---NQSGDLSQYGTGQADSANTTETHARS-----QLALSNNQTLVEVGLLQLIGDPPPEEITKIFGPDRTPGYVFGEDANTGQVAQYHLPSPMFRDFSILFHIQPTTTKAGMLFSITDASQSIVYIGVKLSEVKDGKQQIIFFYTEPGSTFPAATFSVPALTNQWTRFALSVEEEEVALFMECNELKRVRFERSPDEMELEDGSGLFVAQAGGADPDRYQGVIAEIKIKNDPRAAELQC-SDGASGDFGSGLSE-----VVEVTRAPKVIVAPMTVPPIQRNEPKVKEVQETPGQKGEKGTSAGIGPKGDKGQKGELGVKGGPKGQKGDPGASGPPGPPGVSGPS--VVQADGSTVQQITGPR---GPPGPEGPPGKEGEPGDPGEDGKAGEVGPQGFPGTPGDAGKKGDKGDPGVGLRGPPGLPGPPGPPGPGTKTDKLTFIDMEGSGYGPDLENFRGPSGLPGPPGPPGVPGLPGVPGTFGGNSTAIPGPPGLPGRPGQD---GMAGPPGPPGLPGKDGNPGTAGLAGERGTPGAPGSKGSTGEPGIPGTPGETGLAGLPGPIPGPPGPPGPSGRGTADGFDDMEGSGITF-----GGRAIQGRPGIPGEKGDAGF------TGPKGDRGIPGLDGRPGLDGFPGPEGQKGNRGDQGERGEPGRDGI---GIPGPPGPPGQIIYRSSDGGGIG----------EGTRGYKGETGEQGYPGLPGLKGDKGEAGRILGPDGSLFTGGVKGDTGPRGPSGPMGPVGPSGQKGEIGFPGRPGRPGVNGLKGEKGETADPT-GYGIR---GPAGPPGPPGPPGQAVRA---AGPQGYPGQKGERGIPGTKGDQGDVGPAGPPGTFYDFSSFG------------RGEKGEKGEPSVGD--GQGIQGPPGNPGYPGLPGAKGDSIQGPPGPRGPPGAAGVGYEGRQ---GPPGPPGPPGAPVLSVPGPPGPPGPPGPQTVLQTFQTMINLRQSLQEGTIVLVLETADLYVRVRDGFRKILLGEY--VTGGQGNEIAAKEPPVVIYPSGNEPPRNERPPPVN------------PRPPQPP----------QVFPKPEPEDNVPVHTHQEYQAALHLVALNAPLTGSMRSIRGVDFQCFEQARKAGLHGTFRAFLSSRLQDLYSIVRKADRLSVPIVNLRDEPLFDNWEALF-GSEGQMNPGARIYSFEGRDVATDSTWPQKMIWHGSDAKGRRLTESYCETWRTDEIVTGQASSVTNGKLLEQRPQSCNKNFIVLCIENSFMPAGQK >XP_030830245.1 collagen alpha-1(I) chain isoform X3 [Strongylocentrotus purpuratus] ML------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LRPYSGSRGTVFGVTDPYHQTIILSVNITSMSIEQMRISLILTNIDYSTEVAAFLVPSFTNHWTQLALSIRDNQVTLFLDCQELGMQFFDKNQGHIRIPQMAPLFIGHLGTGERVQYRGDIQQIIITNSADSAEEHCPVFSGSGDEPTSMPE-ITYFTQYDAETPSTPLPASVQPPLEQPTLQATPSSQPKGQKGEEGVGGETGPEGPEGPMGPKGEKGGPLGEEGFPGVAGPPGDPGVKG-------EEGD--QGMTGATGEPGV-GVPGLPGVGGEKGDPGRDGYPGVPGVQGPMGIPGVPGPKGDKGEVGLGSQGKPGKEGPKGEPGPSSLE---SFI--EGSG----LEMFVGPPGQPGSPGRPGVPGLDGVPGQPGPAGRDEPGPKGEPGANGSRGPPGVPGAVGPKGDSGMDGNPGMKGERGSSG-PGLEGPEGMKGGPGQNGIPGVPGIAGIPGESPGPAGPPGPPGPSLPPGFQDQEGSGSGVWSGTMGSPGVQGPPGPEGMQGEPGLPGMPGLTGERGERGLPGPRGMEGETGMDGAAGQKGDTGDPGVPGQPGADGFPGPRGVGVQGPPGD--------GLPGPRGIQGLKGDVGEQGPKGDIGFDGVPGMDGQQGAKGYPGPVVGPKGNNGTQGEKGDVGAVGYAGPRGRRGKKGLKGQFGIPGRPGRVGKTGPEGQTG-------------PEGPVGPQGPPGPSGGGEAAF-------PPAFPGEKGSMGAPGSPGPMGPDGVPGAPIEGLEGRPGAQGVPGVPGIDGARGEKGDPGDFFVNDEVFIGPPGEQGLPGRDGQPGQSIKGDTGEPGAEGMPGRGRDGSQ---GPPGPPGMPGHPGYGEQGPPGEPGTPGEPARFATIQDMLDGMRDLEVGTLAFIIRVQELYIRVETGMQQVLLGATFTLPP-----TSEPRPQPRPQPRPQRTTTTTLIPTTTAPFVDP---TEPPQIPG----PGLT-------DRTEEPILPGPEIPVSDQPMLYMYALNTPQEGYMGGISGADFKCWKQAKAAGLKGTYRAFLSSPLQDIRTIVRKQDK-GLPIANGKQEVLFNSWDDIFSTNEAPFHDSFHIYSFDGKDVMTDETWPDKYMWHGSYANGERMAESFCEAWRAQNFARGQASPLSDHKLLGQDEFPCNNAFAVLCVQTARPNARK- >AEL31277.1 multiplexin collagen isoform Ap3 [Drosophila melanogaster] MR------------------------------------------------------------------------------------------------------VLQGVMFALAMIC-------------------------------------------------------------------------AEYTLTDIMNNNQFAGIEFGEAEDGFPAFRFLQTADVKSPYRMLLPEKLY-EFAILITFRQSSLKGGYLFSVVNPLDTVVQLGVHLSPVVKNSYNVSLVYTQADQGRKLASFGVAHVPDKWNSIALQVLSDKVSFYYDCELRNTTLVTREPIELVFDSASTLYIGQAGSIIGGKFEGYLEKINVYGNPDAINVTC-----------------------------MP------PPKAT-----------------------------------------------------------------------------------------------------------------------------------------------------IAPTTADDGSIFY--EGSG---------------------------------------------------------------------------------------------------------------------------------ENILFDSTEAN--------------------------------------------------------------------------------------------------------------------------------------------------ILSDD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GDEATDIFDASGMQ----------PPGQTTLGLVDGEEPYFSASSSVTFQNIDEMTKKSALNPPGTLAYITEEEALLVRVNKGWQYIALGTLVP--------IATPAPPTTVAPSMR------------FDLQSKNLLNSPPPLLNTPTFTTAPEYETW------------------YPRMLRVAALNEPSTGDLQGIRGADFACYRQGRRAGLLGTFKAFLSSRVQNLDTIVRPADR-DLPVVNTRGDVLFNSWKGIFNGQGGFFSQAPRIYSFSGKNVMTDSTWPMKMVWHGSLPNGERSMDTYCDAWHSGDLKGSFASNLDGHKLLEQKRQSCDSKLIILCVEALSQDRKRK >PNJ05978.1 COL18A1 isoform 2 [Pongo abelii] MAPDPRGCRILLLLFCSLAAARADLFNNEDTSHAATTPEPQGPLPAQP-THMAPRNGSTEPATVPGSPEPPSELLEDGQDTPTSAESPDTPEENIAGVGAKILNVAQGIRSFVQLWNDTVPTESLTRAETLVLETPVGPFALPGPSSTPQENGTTLWPSRGTPSSPGAHTTEAGTLPAPTPSPPSLGRPWEEVGLLQLLGDPPPQQVTQTDDPDVGLAYVFGPDANSGQVARYHFPSLFFRDFSLLFHIRPATEGPGVLFAITDSAQAVVLLGVKLSGVQDGHQDISLLYTEPGATHTAASFRLPAFVGQWTHLALSVEGGYVTLYVDCEEFQRMLLARSSRGLELEPGAGLFVAQAGGADPDKFQGMIAELKVRGDPQVSPMHCLSDGASGDFGSGLGDELLREETGAALKPRLPPPPVTTPPLAGEDSRSKEIEEQLGGQTLPGSDSVSTWDGSVRTPGDRVREGGLKGQKGEPGVPGPPGRAGPPGPLGPA--PALQPVPGPQ---GPPGPPGRDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGDKGDPGVGERGPPGPQGPPGPPGPSFRHDKLTFIDMEGSGFGGDLEALRGPRGFPGPPGPPGVPGLPGEPGLFGVNSSDVPGPAGLPGVPGREGPPGFPGLPGPPGPPGREGPPGRTGQKGSLGEAGAPGHKGSKGDPGPAGARGESGLAGSPGPAPGPPGPPGPPGPGLPAGFDDMEGSGGPFWSTARSADGPQGPPGLPGLKGDPGMPGLPGAKGEVGADGAPGFPGLPGREGIAGPQGPKGDRGSQGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDSVPGPEGRPGFAGFPGPAGPKGDLGSKGERGSPGPKGEKGEPGSIFRPDGGALGPVQKGAKGEPGFRGPPGPYGRPGYKGEIGFPGRPGRPGMNGLKGEKGEPGDASLGFGMRGMPGPPGPPGPPGPPGTPVNVFAESSRPGPPGLPGNQGPPGPKGAKGEVGPPGPPGQFFDFLQLEAEMKGEKGDRGDAGQKGERGEPGGGGFFGSRLPGPPGPPGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPGPPTISVPGPPGPPGPPGPPRLWATRQAMLGQVHEVPEGWLIFVAEQEELYVRVRNGFRKVQLEARTPLPRGTDNEVAALQPPVVQLHDSNPYPRREHPHPTARPWRADDILASPPRLPEPQPYPGAPHHSSYVHLRPARPTSPPAHTHRDFQPVLHLVALNSPLSGSMRGIRGADFQCFQQARAVGLAGTFRAFLSSRLQDLYSIVRRADRAAVPIVNLKDELLFPSWEALFSGSEGPLKPGARIFSFDGKDVLRHPTWPQKSVWHGSDPNGRRLTESYCETWRTEASATGQASSLLGGRLLGQNAASCHHAYIVLCIENSFMTASK- >XP_043330533.1 collagen alpha-1(XVIII) chain isoform X5 [Cervus canadensis] MAPDPSSHYGLLLLACCLSAAQADLPGNSAQPTAAPASKTPGSSPVWPTTHVAPRDAPTDWWKVSASPTTPLQRPEAGQGQSPSTASLDLKEENIAGVGAKILNVAQGIRSFVQLWDDTTPAESSARAGTPAPTTPTDPLSTPGPSSTPQDSGTTLQPSTGALSSPDTQRTEAGTLPVPTQLPPSLGRPWMEVGLQQLLGEPPPWQVAVVHDPDVGPAYEFGEDGSGGQAARGFLPSAFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTAARGGRQHVQLLYTEPGDTRTAASFELPALDGRWTRLALSVDGAYARLFVDCKEVQGQPLAHSLHDLHLEPDARLFVAQAGGADPEKFQGLISELRLRRDPRVSPRHCQDDGASGDLGSGLVEEHLREELGASLGPRLPAPPVTSPPLAGEDLRTEEVEESLGAQTLPSLGTVSMWDKSVWSPGSSMEERGLKGQKGEPGAQGPPGPIGPQGPAGPAIEHEGQPVSGPQGPPGPPGPPGKDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGEKGDPGIGPRGPPGPQGPPGPPGPSFKPDRLTFIDMEGSGFGGDLESLRGPRGFPGPPGPPGVPGLPGEPGRFGMNSSDVPGPAGLPGVPGRDGLPGLPGPPGPPGTPGKDGQPGLTGQKGSLGEAGAPGPKGSKGDPGPIGAPGEHGLAGAPGPAPGPPGPPGPPGPGFAAGFDDMEGSGNVFWSTARGADGLQGPPGTPGVKGDPGAVGPPGSKGEVGADGAPGLPGLPGGEGAAGPQGPKGEKGTRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDSVPGPEGRTGFAGFPGPAGPKGDLGAKGQQGIPGPKGEKGEPGTFFGPDGRALTPAQKGAKGEPGFRGPPGPYGRPGHKGEIGFPGRPGRPGMNGLKGEKGEPGDASVGFGMRGPPGPPGPPGPPGPPGTPVNAFVDSGRPGPPGLPGHQGPSGPKGDKGDVGPPGPPGQFFDLLQLGAEMKGEKGDRGAAGQKGERGDPGGGGFFGSSVPGPPGPPGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPGPPTISVPGPPGPPGPPGPPRVWATYQMLVEQVLQVPEGWLIYVADREELYVRVRNGFRKVLLEAHVPLPHGTDNEVAVLQPPLVQLHEGNPYPRREAPHPTARSWRADDILANPPRLPHPQPYPGAPHHGAYAHLRPVPPTASPSHTHHDFQPVLHLVALNSPQSGGLRGIRGADFQCFQQARAAGLAGTFRAFLSSRLQDLYSIVRRADRATLPVVNLRDEVLFPSWEALFSGSEGQLKPGARIFSFDGRDVLQHPAWPQKSVWHGSDPSGRRLTESYCETWRTDTAATGQASSLLAGRLLEQKAAGCHNAFIVLCIENSFMTSSSK >XP_043729625.1 collagen alpha-1(XVIII) chain isoform X5 [Cervus elaphus] MAPDPSSHYGLLLLACCLSAAQADLPRNSAQPTAAPASKTPGSSPVWPTTHVAPRDAPTDWWKVSASPTTPLQRPEAGQGQSPSTASLDLKEENIAGVGAKILNVAQGIRSFVQLWDDTTPAESSARAGTPAPTTPTDPLSTPGPSSTPQDSGTTLQPSTGALSSPDTQRTEAGTLPVPTQLPPSLGRPWMEVGLQQLLGEPPPWQVAVVHDPDVGPAYEFGEDGSGGQAARGFLPSAFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTAARGGRQHVQLLYTEPGDTRTAASFELPALDGRWTRLALSVDGAYARLFVDCKEVQGQPLAHSLHDLHLEPDARLFVAQAGGADPEKFQGLISELRLRRDPRVSPRHCQDDGASGDLGSGLVEEHLREELGASLGPRLPAPPVTSPPLAGEDLRTEEVEESLGAQTLPSLGTVSMWDKSVWSPGSSMEERGLKGQKGEPGAQGPPGPIGPQGPAGPAIEHEGQPVSGPQGPPGPPGPPGKDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGEKGDPGIGPRGPPGPQGPPGPPGPSFKPDRLTFIDMEGSGFGGDLESLRGPRGFPGPPGPPGVPGLPGEPGRFGMNSSDVPGPAGLPGVPGRDGLPGLPGPPGPPGTPGKDGQPGLTGQKGSLGEAGAPGPKGSKGDPGPIGAPGEHGLAGAPGPAPGPPGPPGPPGPGFAAGFDDMEGSGNVFWSTARGADGLQGPPGTPGVKGDPGAVGPPGSKGEVGADGAPGLPGLPGGEGAAGPQGPKGEKGTRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDSVPGPEGRTGFAGFPGPAGPKGDLGAKGQQGIPGPKGEKGEPGTFFGPDGRALTPAQKGAKGEPGFRGPPGPYGRPGHKGEIGFPGRPGRPGMNGLKGEKGEPGDASVGFGMRGPPGPPGPPGPPGPPGTPVNAFVDSGRPGPPGLPGHQGPSGPKGDKGDVGPPGPPGQFFDLLQLGAEMKGEKGDRGAAGQKGERGDPGGGGFFGSSVPGPPGPPGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPGPPTISVPGPPGPPGPPGPPRVWATYQMLVEQVLQVPEGWLIYVADREELYVRVRNGFRKVLLEAHVPLPHGTDNEVAVLQPPLVQLHEGNPYPRREAPHPTARSWRADDILANPPRLPHPQPYPGAPHHGAYAHLRPVPPTASPSHTHHDFQPVLHLVALNSPQSGGLRGIRGADFQCFQQARAAGLAGTFRAFLSSRLQDLYSIVRRADRATLPVVNLRDEVLFPSWEALFSGSEGQLKPGARIFSFDGRDVLQHPAWPQKSVWHGSDPSGRRLTESYCETWRTDTAATGQASSLLAGRLLEQKAAGCHNAFIVLCIENSFMTSSSK >KAB0373800.1 hypothetical protein FD755_014056 [Muntiacus reevesi] MAPDPSSHHSLLLLACCLSAAQADLPGNSAQPTAAPASKTLGSSPVWPTTHVDPRDAPTDWWKVSASPTTPLQRPEAGQGQSPSTASLDLKEENIAGVGAKILNVAQGIRSFVQLWDDTTPAESSARAGTPAPTTPTDPLSTPGPSSTPQDSRTTLQPSTRALSSPDTQRTEADTLPLPTQLPPSLGRPWVEVGLQQLLGEPPPWQVAVVHDPDVGPAYEFGEDGSGGQAARGLLPSAFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTAARGGRQHVQLLYTEPGDTRTAASFELPALDGRWTRLALSVDGAYARLFVDCKEVQGQPLAHSLHDLHLEPDARLFVAQAGGADPEKFQGLISELRLRRDPRVSPRHCQDDGASGDLGSGLMEEHLREELGASLGPRLPAPPVTSPPLAGEDLRTEEVEESLGAQTLPSLGTVSTWDESVWSPGSSMKERGLKGQKGEPGAQGPPGPIGPQGPAGPAIEHEGQPVSGPQGPPGPPGPPGKDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGEKGDPGVGPRGPPGPQGPPGPPGPSFKPDRLTFIDMEGSGFGGDLESLRGPRGFPGPPGPPGVPGLPGEPGRFGMNSSDIPGPAGLPGVPGRDGPPGLPGPPGPPGTPGKDGQPGLTGQKGSVGEAGAPGPKGSKGDPGPIGAPGEHGLAGAPGPAPGPPGPPGPPGPGFAAGFDDMEGSGNVFWSTARGADGLQGPPGTPGVKGDPGAVGPPGSKGEVGADGAPGLPGLPGREGAAGSQGPKGEKGTQGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDSVPGPEGRAGFAGFPGPAGPKGDLGAKGQQGIPGPKGEKGEPGAFFGPDGRALTPAQKGAKGEPGFRGPPGPYGRPGHKGEIGFPGRPGRPGMNGLKGEKGEPGDASVGFGVRGPPGPPGPPGPPGPAGTPVNAFVDSGRPGPPGLPGHQGPSGPKGDKGDVGPPGP----VLLLQVG-EIRSSSWTPGHCQPKGDRGQGSGGG-ASSSLP----------FKLSKAEG-RGQHGARQAEGGQTCGVRTCESGKGQAG--------AVTAAPPPGPPGTASPCRVWATYQMLVEQVLQVPEGWLIYVADREELYVRVRNGFRKVLLEAHVPLPHGTDNEVAVLQPPLVQLHEGNPYPRREAPHPTARAWRADDILANPPRLPHPQPYPGAPHHGAYAHLRPVPPTASPSHTHHDFQPVLHLVALNSPQSGGLRGIRGADFQCFQQARAAGLAGTFRAFLSSRLQDLYSIVRRADRATLPVVNLRDEVLFPSWEALFSGSEGQLKPGARIFSFDGRDVLQHPAWPQKSVWHGSDPSGRRLTESYCETWRTDTAATGQASSLLAGRLLEQKAAGCHNAFIVLCIENSFMTSSSK >KAB0366097.1 hypothetical protein FD754_010253 [Muntiacus muntjak] MAPDPSSHHSLLLLACCLSAAQADLPGNSAQPTAAPASKTPGSSPVWPTTHVDPRDAPTDWWKVSASPTTPLRRPEAGQGQSPSTASLDLKEENIAGVGAKILNVAQGIRSFVQLWDDTTPAESSARAGTPAPTTPTDPLSTPGPSSTPQDSRTTLQPSTRALSSPDTQRTEAGTLPLPTQLPPSLGRPWVEVGLQQLLGEPPPWQVAVVHDPDVGPAYEFGEDGSGGQAARGLLPSAFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTAARGGRQHVQLLYTEPGATRTAASFKLPALDGRWTRLALSVDGAYTRLFVDCKEVQGQPLAHSLHDLHLEPDARLFVAQAGGADPEKFQGLISELRLRRDPRVSPRHCQDDGASGDLGSGLMEEHLREELGASLGPRLPAPPVTSPPLAGEDLRTEEVEESLGAQTLPSLGTVSTWDESVWSPGSSMKERGLKGQKGEPGAQGPPGPIGPQGPAGPDIEHEGQPVSGPQGPPGPPGPPGKDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGEKGDPGVGPRGPPGPQGPPGPPGPSFKPDRLTFIDMEGSGFGGDLESLRGPRGFPGPPGPPGVPGLPGEPGRFGMNSSDIPGPAGLPGVPGRDGPPGLPGPPGPPGTPGKDGQPGLTGQKGSVGEAGAPGPKGSKGDPGPIGAPGEHGLAGAPGPAPGPPGPPGPPGPGFAAGFDDMEGSGNVFWSTARGADGLQGPPGTPGVKGDPGAVGPPGSKGEVGADGAPGLPGLPGREGAAGPQGPKGEKGTQGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDSVPGPEGRAGFAGFPGPAGPKGDLGAKGQQGIPGPKGEKGEPGAFFGPGPRALTPAQNGAKGEPGFRGPPGPYGRPGHKGEIGFPGRPGRPGMNGLKGEKGEPGDASVGFGVRGPPGPPGPPGPPGPAGTPVNAFVDSGRPGPPGLPGHQGPSGPKGDKGDVGPPGP----VLLLQVG-EIRSSSWTPGHCQPKGDRGQGSGGG-ASSSLP----------FKLSKAEG-RGQHGARQAEGGQTCGVRTCESGKGQAG--------AVTAAPPPGPPGTASPCWVWATYQMLVEQVLQVPEGWLIYVADREELYVRVRNGFRKVLLEAHVPLPHGTDNEVAVLQPPLVQLHEGNPYPRREAPHPTARSWRADDILANPPRLPHPQPYPGAPHHGAYAHLRPVPPTASPSHTHHDFQPVLHLVALNSPQSGGLRGIRGADFQCFQQARAAGLAGTFRAFLSSRLQDLYSIVRRADRAALPVVNLRDEVLFPSWEALFSGSEGQLKPGARIFSFDGRDVLQHPAWPQKSVWHGSDPSGRRLTESYCETWRTDTAATGQASSLLAGRLLEQKAAGCHNAFIVLCIENSFMTSSSK >KAF4020675.1 hypothetical protein G4228_012853 [Cervus hanglu yarkandensis] MAPDPSSHYGLLLLACCLSAAQADLPGNSAQPTAAPASKTPGSSPVWPTTHVAPRDAPTDWWKVSASPTTPLQRPEAGQGQSPSTASLDLKEENIAGVGAKILNVAQGIRSFVQLWDDTTPAESSARAGTPAPTTPTDPLSTPGPSSTPQDSGTTLQPSTGALSSPDTQRTEAGTLPVPTQLPPSLGRPWMEVGLQQLLGEPPPWQVAVVHDPDVGPAYEFGEDGSGGQAARGFLPSAFFQDFSLLVRVRPASARAGVLFAVTDPAQAVVSVGVKLTAARGGRQHVQLLYTEPGDTRTAASFELPALDGRWTRLALSVDGAYARLFVDCKEVQGQPLAHSLHDLHLEPDARLFVAQAGGADPEKFQGLISELRLRRDPRVSPRHCQDDGASGDLGSGLVEEHLREELGASLGPRLPAPPVTSPPLAGEDLRTEEVEESLGAQTLPSLGTVSMWDESVWSPGSSMKERGLKGQKGEPGAQGPPGPIGPQGPAGPAIEHEGQPVSGPQGPPGPPGPPGKDGTPGRDGEPGDPGEDGKPGDTGPQGFPGTPGDVGPKGEKGDPGIGPRGPPGPQGPPGPPGPSFKPDRLTFIDMEGSGFGGDLESLRGPRGFPGPPGPPGVPGLPGEPGRFGMNSSDVPGPAGLPGVPGRDGLPGLPGPPGPPGTPGKDGQPGLTGQKGSL---------GSKGDPGPIGAPGEHGLAGAPGPAPGPPGPPGPPGPGFAAGFDDMEGSGNVFWSTARGADGLQGPPGTPGVKGDPGAVGPPGSKGEVGADGAPGLPGLPGGEGAAGPQGPKGEKGTRGEKGDPGKDGVGQPGLPGPPGPPGPVVYVSEQDTVLSPQGRTGFAGFPGPAGPKGDLGAKGQQGIPGPKGEKGEPGTFFGPDGRALTPAQKGAKGEPGFRGP------------------PGRPGMNGLKGEKGEPGDASVGFGMRGPPGPPGPPGPPGPPGTPVN-------------------------------------------------GEKGDRGAAGQKGERGDPGGGGFFGSSVPGPPGPPGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPPGPPGPPTISVPGPPGPPGPPGPPRVWATYQMLVEQVLQVPEGWLIYVADREELYVRVRNGFRKVL-----------DNEVAVLQPPLVQLHEGNPYPRREAPHPTARSWRADDILANPPRLPHPQPYPGAPHHGAYAHLRPVPPTASPSHTHHDFQPVLHLVALNSPQSGGLRGIRGADFQCFQQARAAGLAGTFRAFLSSRLQDLYSIVRRADRATLPVVNLRDEVLFPSWEALFSGSEGQLKPGARIFSFDGRDVLQHPAWPQKSVWHGSDPSGRRLTESYCETWRTDTAATGQASSLLAGRLLEQKAAGCHNAFIVLCIENSFMTSSSK >NP_001082208.1 collagen type XVIII alpha 1 S homeolog precursor [Xenopus laevis] MILR------------------------------------------------------------------------------------------------LLLYAAYH----------------------------------------------------------------------------------LEVGLLQLIGEPVPSQITKVLGPDKTPAYVFDKEANTGQVAQYHLPNPMYRDFSLLFHVQPTTNKAGILFAITDASQXIVYIGVKLSEAKDGKQDIIFYYTEPGSSYIAATFNVPSLVNRWSRFSISVEDEEVVLFMNCDEMERVRFERSPDEMELEDGSGLFVAQAGGADPDRYQGVIADLKIVADPRAAEQQC-SDGISGDFGSGIAD-----LVTASPPVVIKQPPINVPPIQK-----KEIVQT-GQQGIKGVSLASDSKAEKGQKGEVGFKGGPKGQKGDPGIMGPRGHPGPPGPS--VLQSDGTTVQQVTGPP---GPQGPAGPPGNDGEPGDPGEDGKTGEVGPQGFPGTPGDIGQKGEKGDSGVGMRGPSGPPGPPGPPGPS-RMDKLTFIDMEGSGYGGDLENVRGPSGLPGPPGPPGVPGLPGVPGTFGMNNTGLPGPPGLPGLPGKE---GFPGPPGPSGPPGKDGLTGAAGVAGIRGEPGAPGVKGSPGEPGQPGAVGQPGLAGLPGPMPGPPGPPGPVGRGSAIGFDDMEASGLGF----R--EGTQGLSGLPGAKGEQGNPGMPGLPGVKGESGSPGPEGRQGLDGFPGLEGLKGEKGEHGERGEPGRDGV---GIPGPPGPPGQVLYLPSDDAISGPEGRQGVAGLPGPRGPKGDQGLDGFPGTSGAKGERGEPGLIMRPDGTIYTDLSKAEKGEQGPTGPAGSVGPSGQKGEIGFPGRPGRPGMNGLKGEKGDPA--SGGFGLN---GPPGPPGPPGPPGSVVNI--------PRAYPGQKGERGFPGPKGDVGPAGPPGSFYDLSTFASILTRE------AGLKGEKGEPGGGD-NGQGIPGPSGNPGYPGLPGAKGESVQGPPGPAGPPGHPGTGYEGRQ---GPPGPPGPPGLPTISIPGPPGPPGPPGLPTVLQTYQTMINLAHRLQEGTIVLVQERAELYVRVREGFRKILLGEYSALSGGQDNEVAAEQAPVVPYPHRNENSNNANVPSGARPW-SDPRLPEPPRVDPPRVDPPPPDH--HHHGNPHPLEPSPVHTHQQFNPALHLVALNAPLSGSMKSIRGVDFQCFEQARKSGLHGTFRAFLSSRLQDLYSIVRRADRQSVQIVNLRDEVLYDNWESLFSGSEAQMRPGARIFSFDGKDVATDPTWPQKMVWHGSDAKGRRLTESYCETWRTDEAVTSQASSLTSGKLLEQRPQSCNKNFIVLCIENSFMTNNRK >XP_015820964.1 PREDICTED: collagen alpha-1(XVIII) chain [Nothobranchius furzeri] MNMRC-------------------------------------------------------------------------------------------------------LERLVCCV--------------------------------------------------------------------------NGVSLLQLIGDPPPDGIPQVDGPDNNPGYVFGPDTSSGQMALAHFPSSFYRNFALIFSVKPTSDQGGVIFSITDSSQEVIDVGVRLAAVQGGHQDVIFYYNYLGKSHEAARFPVPSMKDTWNWFAIAVQDDKVMFYHSCEEPQVMRMERSADKLELESGAGVFVGGAGGSTHDKFEGVISELRVVGDPRAAERLC-SDMASGE-GSGVEGVPNRYREKHRYTTTTPLPPIPQPPLNRATVRES-----VGAKGEKGFGSRGGIRGEKGEPGERGLKG---GKKGDPGPPGVPGPPGPPGPAAEYSVSDGSVVSRVPGPRGPPGAPGSQGPPGEDGEPGDPGEDGKTGPQGPPGFPGTPGDSGQKGEKGDRGEGQPGPRGLPGPPGAPGPGY---RSTFEDMEASGF-SDLETVRGPRGPPGPPGPPGP---PGPSTSGSTSNS------GAFGPPGKDGAPGLPGSP---GLPGSDGPPGAPGPRGEKGDPGAIGQKGAQGDLGLPGPPGEPGLAGLPGPMVGPPGPAGPPGPSYRVGFDDMEGS-----SGLRGPEGIQGSPGLPGHPGEP---GLPGADGPKGDQGPTGKDGLPGLDGFPGPPGQKGDRGDKGETGDPGRDGTGLPGPPGPPGPPGQIIYQPSDRG--GAQGLPGRAGLPGPVGPKGERGDPGPAGY-GVKGEKGEPGLIIGPDGAPLYTGQKGDRGPAGPVGPSGPYGPPGLKGEIGMPGRPGRPGVNGYKGEKGEPGGGA-GYGYPGVAGPPGPPGPPGPPGPAINAYDEASR-------SYRVVKGDKGERGDR---GPPGTVFDIYTLKNQLKGD---RGDTGVKGEKGEPGHG-YYDPRIQGPPGPPGNPGLPGPKGDSIVGPSGPQGPPGPPGVGYDGRPGPPGPPGPPGPATSPPVSVPGPPGPPGPPGNPTVLRSYDTMIATARQQPEGSLIYIIDKADLYLRVREGLRQVMLGQYSPFSRDLENEVVEVQPPPVIVYPHN-SQNNGAGHYSDRPIEPP-------------------------QPRPHQPVPGSTGLVETPESVLHLAALNAPQTGDMRGIRGADFMCFQQARAVGLKGTFRAFLSSKLQDLYTIVRTLDRKTFPIVNLKNQVLFTSWESIFRENSSKMRENVPIYSFDGRDVLRDSAWPEKMVWHGSSSEGKRNMDHYCETWRIDNALTGLASSLQSGYLLQQNRSSCSGSYIVLCIENAFMSSSKK >XP_030285041.1 collagen alpha-1(XVIII) chain isoform X1 [Sparus aurata] MRTQF---GVLLLLALWVVHTDAWFTGTTTLP---------------PT------------GSQAGSGEPPS--------------------ENIARTGLEIIDEGHGIQKVVQTETTQAPRLTTTT------------------------------------QPANEHASEKG----------------SGVSLLQLIGDPPPSEIRRVYGFDNIPGYDFGPDANTGQLARAHLPSPFFRDFALIFYLKPTTDRGGVIFSVTDASQKIMYVGVKLSAVQGGNQNVILYYTEPDSSYEAARFRVPSMRDTWTRFAIAVRDEKVMFYHNCDDPQVMRIERSPDEMELEAGAGVFVGQAGGADPDKFLGVIGELRVVGDPRAAERHC-SDMASGD-GSGYVEPPKPAVDNPRWTTTPPSRPIQQPPVTKSVARET-----DGAKGEKGSSSRGGARGEKGEPGEKGLKG---GTKGEPGPAGPPGPAGPPGPATEFSVSDGSVSSRGPGPRGPPGSPGPKGPPGNDGEPGDPGEDGKTGPEGPPGFPGTPGDTGPKGDKGDRGDGQPGPRGPPGPPGPPGTGL---RSTFVDMEGSGF-PDLDSIR---GLPGPQGPPGPPGPPGPSTATTGLSS------GAFGPPGKDGAPGQPGLA---GLPGTDGLPGAPGPKGEKGDPGAIGQKGAQGEPGVPGTPGEAGLAGLPGPMVGQPGPPGPPGPSYRVGFDDMEGSGGGFSNGLRGPEGTQGSPGLPGLPGKP---GFPGMPGQKGSEGSVGRDGQPGLDGFPGPKGPKGDKGDKGETGNPGRDGTGHPGPPGPPGPPGEIIYRTSDNGGAGPQGLPGQAGFPGPIGPKGDRGDPGPVGY-GVKGEKGEPGLIVGPDGNLLSTGVKGDRGPAGPVGPTGPYGPPGLKGEIGMPGRPGRPGVNGYKGEKGEPSVGS-GYGYPGVPGQPGPPGPPGPPGPAINRYDDSSR-------NYPATKGEKGERGDRGIPGIPGAAFDIYAFKNELKGE---RGETGVKGEKGEPSGG-YYDPRFQGPQGPPGKPGLPGPKGEPVMGPPGPQGPPGSPGIGYDGRPGPPGPPGPPGPQ-SPPVSVPGPPGPPGPPGSPSVLRSYDVMIATARRQAEGSLIYIIDKADLYLRVRDGLRQVMLGEYSPFFRDLENEVAEVQPPPVILYPQSESQNNGAGHYSQRPIEPPP-PQYDPRFPDPRRTGQTDRYPVTPQRRPSPPVVHPVGHVDTSVSGLHLIALNAPQSGNMRGIRGADFLCFQQARAIGLKGTFRAFLSSKLQDLHTIVRRSDRDSLPILNLKDQVLFSSWEAIFGDNASKMRENVPIYSFDGRDILRDSAWPEKMVWHGSSNKGHRQTDHYCETWRAGDAVTGLASSLQSGHLLQQSSTSCSGSYIVLCIENAFTTHSKK >XP_023806434.1 collagen alpha-1(XVIII) chain [Oryzias latipes] MR----------------------------------------------------------------------------------------------------------NERLVCCVL-------------------------------------------------------------------------NGVSLLQLIGDPPPSEISQVYGPDNAIGYVFGPDAKMGQLAVAHFPTPFYRDFSLNFHLKPTSNEGGVVFSITDSSQQVIVVGVKLSTVERQTQDVIFYYSETGSSYEAARFQVTSMTDTWTRFSISVRDDKVAFYFNCDSPVVKRFERSPDDMELERGSGVFVGQTGGPDPERFLGVISELRVVGDPRAAETFC-SDMASGE-GSGYEEPQKQNMDRNRFSTAPPFMSIQKPPLATAVVRDTAIKSEVGAKGEKGSSSASGSRGEKGEPGEKGTKG---GKKGDPGQPGPPGPPGPPGPSTEYVPSDGTVVSKVQGPRGPPGPPGPQGQPGEDGEPGDPGEDGKTGSPGPQGFPGTPGDPGRKGDKGDRGEGQPGPRGAPGPPGPPGPGM---RSTFVDMEGSGF-PDLESLR---GLPGPPGPPGPPGPPGSSVTGPAMGS------GAFGPPGRDGAAGQP------GLPGTDGLPGAPGPKGDKGDPGAIGEKGDRGEPGLPGSPGESGLAGLPGPMVGPPGPPGPPGSNYRVGFDDVEASGGRFTSGLRGPQGAQGPPGLPGNPGRP---GLPGVQGQKGREGPPGRDGQPGLDGFPGTPGQKGERGDKGDRGEAGRDGAGLPGPPGPPGPPGQIFYQPSDNGRAGPQGLPGQAGFPGPVGPKGDTGNPGLPGL-GVKGEKGEPGLIIGPDGNPLYTGQKGDIGPQGPAGPMGPQGPPGLKGEIGMPGRPGRPGVNGYKGEKGEPSGGL-GHG--GVPGPPGPPGPPGPPGPPFNRYDDISR-------NYP-VKGEKGERGD---PGFPGTAFDIYTLKNQWKGE---RGDPGVKGEKGEPGAG--HDPQYQGPLGP---PGLPGPKGDSIMGPPGPQGPPGSPGIGYDGRPGPPGPPGPPGPPWSQPVSVPGPPGPPGPPGHPMVLRSYDTLIATARSQEEGSLIYILDKADLYLRVRDGLRQVMLGEYNPFFRDFDNEVAEAQPPPVVLYPHSHSQNNGASQYSQRPIETPP-PQYEPRFPDQQRPSQTDKYAVTPQRRPNPPVPGP---VETSTLGLRLIALNTPQSGNMKGIRGPDYLCFEQARAAGLRGTFRAFLSSKVQDLHTIVRHSDREKPPIVNLKNQVLFDSWQSIFGESVSKMRKNVPIYSFDGRDILRDSAWPEKMVWHGSSKKGHRQTDQYCEAWRAGDAVTGLASSLQSSHLLQQTPTSCSRACIVLCIENAMVSPSK-
PhyML tree of selected proteins (XP_021334397_1_collagen_type_XVIII__alpha_1_isoform_X3__Danio_rerio_:0.34241683,(XP_023806434_1_collagen_alpha_1_XVIII__chain__Oryzias_latipes_:0.24207179,(XP_030285041_1_collagen_alpha_1_XVIII__chain_isoform_X1__Sparus_aurata_:0.15619373,XP_015820964_1_PREDICTED__collagen_alpha_1_XVIII__chain__Nothobranchius_furzeri_:0.27064102):0.04093929):0.11913947,((NP_001082208_1_collagen_type_XVIII_alpha_1_S_homeolog_precursor__Xenopus_laevis_:0.30783522,XP_040213558_1_collagen_alpha_1_XVIII__chain_isoform_X1__Rana_temporaria_:0.31064634):0.19705957,((((((XP_020927188_1_collagen_alpha_1_XVIII__chain_isoform_X1__Sus_scrofa_:0.17091846,((XP_024830782_1_collagen_alpha_1_XVIII__chain_isoform_X1__Bos_taurus_:0.0234615,(XP_020730828_1_collagen_alpha_1_XVIII__chain__Odocoileus_virginianus_texanus_:0.05753275,((KAF4020675_1_hypothetical_protein_G4228_012853__Cervus_hanglu_yarkandensis_:0.0033753,(XP_043330533_1_collagen_alpha_1_XVIII__chain_isoform_X5__Cervus_canadensis_:0.00000001,XP_043729625_1_collagen_alpha_1_XVIII__chain_isoform_X5__Cervus_elaphus_:0.00079774):0.00159533):0.00818911,(KAB0373800_1_hypothetical_protein_FD755_014056__Muntiacus_reevesi_:0.00332845,KAB0366097_1_hypothetical_protein_FD754_010253__Muntiacus_muntjak_:0.00784692):0.05938863):0.00737287):0.014181):0.00458037,(XP_027816975_1_collagen_alpha_1_XVIII__chain_isoform_X3__Ovis_aries_:0.00528327,XP_017907685_1_PREDICTED__collagen_alpha_1_XVIII__chain_isoform_X1__Capra_hircus_:0.00832377):0.02764979):0.10123563):0.07311544,(XP_038299617_1_collagen_alpha_1_XVIII__chain_isoform_X1__Canis_lupus_familiaris_:0.10621443,XP_023094382_1_collagen_alpha_1_XVIII__chain_isoform_X1__Felis_catus_:0.06024669):0.05994711):0.04160349,(PNJ05978_1_COL18A1_isoform_2__Pongo_abelii_:0.01717032,((sp_P39060_2_COIA1_HUMAN_Isoform_3_of_Collagen_alpha_1_XVIII__chain_OS_Homo_sapiens_OX_9606_GN_COL18A1:0.01311128,(sp_P39060_COIA1_HUMAN_Collagen_alpha_1_XVIII__chain_OS_Homo_sapiens_OX_9606_GN_COL18A1_PE_1_SV_5:0.00000001,sp_P39060_1_COIA1_HUMAN_Isoform_2_of_Collagen_alpha_1_XVIII__chain_OS_Homo_sapiens_OX_9606_GN_COL18A1:0.00000001):0.00000001):0.00720972,(XP_030860999_1_collagen_alpha_1_XVIII__chain__Gorilla_gorilla_gorilla_:0.04130295,(XP_009439942_2_collagen_alpha_1_XVIII__chain_isoform_X1__Pan_troglodytes_:0.00244685,XP_034803833_1_collagen_alpha_1_XVIII__chain_isoform_X1__Pan_paniscus_:0.00326828):0.00412937):0.0010097):0.01251337):0.12781609):0.0427021,(NP_034059_2_collagen_alpha_1_XVIII__chain_isoform_2_precursor__Mus_musculus_:0.05342924,NP_445941_2_collagen_alpha_1_XVIII__chain_precursor__Rattus_norvegicus_:0.05276228):0.13266817):0.30964216,(AEL31277_1_multiplexin_collagen_isoform_Ap3__Drosophila_melanogaster_:2.56166302,XP_030830245_1_collagen_alpha_1_I__chain_isoform_X3__Strongylocentrotus_purpuratus_:1.6499315):0.65232362):0.12627729,((XP_013226958_1_LOW_QUALITY_PROTEIN__collagen_alpha_1_XVIII__chain__Columba_livia_:0.12772067,(XP_010711461_1_collagen_alpha_1_XVIII__chain_isoform_X1__Meleagris_gallopavo_:0.05455071,XP_025007836_2_collagen_alpha_1_XVIII__chain_isoform_X1__Gallus_gallus_:0.05587199):0.08682769):0.18515006,(XP_006022141_1_collagen_alpha_1_XVIII__chain_isoform_X2__Alligator_sinensis_:0.02534648,XP_019347546_1_PREDICTED__collagen_alpha_1_XVIII__chain_isoform_X1__Alligator_mississippiensis_:0.04124617):0.18097365):0.12907109):0.10944339):0.59209457);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)