PB0211

DATABASE

Click here to access PB0211 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0211	P08758	Annexin A5	ANXA5	ANX5, CPB-I, ENX2, HEL-S-7, PP4, RPRGL3, VAC-alph	Homo_sapiens	This protein is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.

Domains

Gene Ontology

PF00191 (4_Annexin)

GO:0004859 (enables) phospholipase inhibitor activity GO:0005509 (enables) calcium ion binding GO:0005515 (enables) protein binding GO:0005543 (enables) phospholipid binding GO:0005544 (enables) calcium-dependent phospholipid binding GO:0007165 (involved in) signal transduction GO:0007596 (involved in) blood coagulation GO:0007599 (involved in) hemostasis GO:0010033 (involved in) response to organic substance GO:0043066 (involved in) negative regulation of apoptotic process GO:0043086 (involved in) negative regulation of catalytic activity GO:0050819 (involved in) negative regulation of coagulation GO:0005576 (located in) extracellular region GO:0005737 (located in) cytoplasm GO:0005829 (located in) cytosol GO:0005925 (located in) focal adhesion GO:0009897 (located in) external side of plasma membrane GO:0016020 (located in) membrane GO:0070062 (located in) extracellular exosome GO:0072563 (located in) endothelial microparticle GO:0062023 (part of) collagen-containing extracellular matrix

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|P08758|ANXA5_HUMAN Annexin A5 OS=Homo sapiens OX=9606 GN=ANXA5 PE=1 SV=2 MAQVLRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTL FGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPE ELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALF QAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAV VKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMI KGDTSGDYKKALLLLCGEDD >tr|Q6P0V8|Q6P0V8_DANRE Annexin OS=Danio rerio OX=7955 GN=anxa5b PE=1 SV=1 MAGRGTVKPQSGFNANSDAEVLYKAMKGLGTDEDSILQLLTKRSNGQRQEIKAAYKTLHG KDLVNDLKSELGGKFEDLIVALMTPPIIYEVTCLRNAIKGAGTDEKVLIEILASRSPNEV NEIKSSYKREHDKDLEEDVTGDTGGHFERMLVVLLQASRQQGIQESLIQSDAQALFAAGE QKYGTDEGQFITILGNRSNAHLRRVFEEYRKLSGFEIEESIQRETSGSLQEILLAVVKCA RSVPGYFADSLYAAMKGAGTDDQTLIRIMVTRSEVDLLDIRAEFRKRFATSLHKMIQSDT SGDYRKTLLLLCGGDDA
Selected proteins from model organisms >sp|P08758|ANXA5_HUMAN Annexin A5 OS=Homo sapiens OX=9606 GN=ANXA5 PE=1 SV=2 MAQVLRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTL FGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPE ELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALF QAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAV VKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMI KGDTSGDYKKALLLLCGEDD >tr|Q6P0V8|Q6P0V8_DANRE Annexin OS=Danio rerio OX=7955 GN=anxa5b PE=1 SV=1 MAGRGTVKPQSGFNANSDAEVLYKAMKGLGTDEDSILQLLTKRSNGQRQEIKAAYKTLHG KDLVNDLKSELGGKFEDLIVALMTPPIIYEVTCLRNAIKGAGTDEKVLIEILASRSPNEV NEIKSSYKREHDKDLEEDVTGDTGGHFERMLVVLLQASRQQGIQESLIQSDAQALFAAGE QKYGTDEGQFITILGNRSNAHLRRVFEEYRKLSGFEIEESIQRETSGSLQEILLAVVKCA RSVPGYFADSLYAAMKGAGTDDQTLIRIMVTRSEVDLLDIRAEFRKRFATSLHKMIQSDT SGDYRKTLLLLCGGDDA >NP_033803.1 annexin A5 [Mus musculus] MATRGTVTDFPGFDGRADAEVLRKAMKGLGTDEDSILNLLTSRSNAQRQEIAQEFKTLFGRDLVDDLKSE LTGKFEKLIVAMMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELSAIKQVYEEEYGSNLEDDVV GDTSGYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDK YMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVVVSRSEIDLF NIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD >NP_037264.2 annexin A5 [Rattus norvegicus] MALRGTVTDFSGFDGRADAEVLRKAMKGLGTDEDSILNLLTARSNAQRQQIAEEFKTLFGRDLVNDMKSE LTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQVYEEEYGSNLEDDVV GDTSGYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKFITILGTRSVSHLRRVFDK YMTISGFQIEETIDRETSGNLENLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVIVSRSEIDLF NIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD >NP_001035567.3 annexin A5 [Bos taurus] MAQVLRGTVADFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLK SELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDD VVGDTSGYYQRMLVVLLQANRDPDARIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVF DKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVVVSRSEID LYNIRKEFRKNFGTSLYSMIKGDTSGDYKKALLLLCGGEDD >NP_001026709.1 annexin A5 [Gallus gallus] MAKYTRGTVTAFSPFDARADAEALRKAMKGMGTDEETILKILTSRNNAQRQEIASAFKTLFGRDLVDDLK SELTGKFETLMVSLMRPARIFDAHALKHAIKGAGTNEKVLTEILASRTPAEVQNIKQVYMQEYEANLEDK ITGETSGHFQRLLVVLLQANRDPDGRVDEALVEKDAQVLFRAGELKWGTDEETFITILGTRSVSHLRRVF DKYMTISGFQIEETIDRETSGDLEKLLLAVVKCIRSVPAYFAETLYYSMKGAGTDDDTLIRVMVSRSEID LLDIRHEFRKNFAKSLYQMIQKDTSGDYRKALLLLCGGDDE >NP_001009099.1 annexin A5 [Pan troglodytes] MAQVLRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLK SELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDD VVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRKVF DKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEID LFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGEDD >NP_001301047.1 annexin A5 [Canis lupus familiaris] MAQVLKGTVTPFPGFDERADAEVLRKAMKGLGTDEESILTLLTSRSNAQRQEIAAAFKTLFGRDLLDDLK SELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDD VVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVF DKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVVVSRSEID LFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLMLCGGEDD >XP_008266130.1 PREDICTED: annexin A5 [Oryctolagus cuniculus] MAQALRGTVTAFPGFDERADAEILRKAMKGLGTDEDSILTLLTARSNGQRQEIADAFKTLYGRDLLDDLK SELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPAELTAIKQVYEEEYGSSLEDD VMGDTSGYYQRMLVVLLQANRDPDSGIDTAQVEQDAQTLFQAGELKWGTDEEKFITIFGTRSVSHLRRVF DKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEID LYNIRKEFRKNFGTSLYSMIKDDTSGDYKKALLLLCGGDDD >XP_002815150.2 annexin A5 [Pongo abelii] MAQVLRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLK SELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDD VVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRKVF DKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEID LFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGEDD >XP_003129266.2 annexin A5 [Sus scrofa] MAQVLRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLK SELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKILTEIIASRTPEELRAIKQVYEEEYGSSLEDD VVGDTSGYYQRMLVVLLQANRDPDGRIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVF DKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEID LFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD >XP_010708237.1 annexin A5 [Meleagris gallopavo] MYTRGTVTAFSPFDARADAEALRKAMKGMGTDEETILKILTSRNNAQRQEIASAFKTLFGRDLVDDLKSE LTGKFETLMVSLMRPARIFDAHALRHAIKGAGTNEKVLTEILASRTPAEVQNIKQVYMQEYEANLEDKIT GETSGHFQRLLVVLLQGNRDPDGRVDEALVEKDAQVLFRAGELKWGTDEETFITILGTRSVSHLRRVFDK YMTISGFQIEETIDRETSGDLEKLLLAVVKCIRSVPAYFAETLYYSMKGAGTDDDTLIRVMVSRSEIDLL DIRHEFRKNFAKSLHQMIQKDTSGDYRKALLLLCGGDDE >XP_003816466.1 annexin A5 [Pan paniscus] MAQVLRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLK SELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDD VVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRKVF DKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEID LFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGEDD >XP_006930945.1 annexin A5 [Felis catus] MAQVKGTVTPFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIATAFKTLFGRDLLDDLKS ELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDV VGDTSGYYQRMLVVLLQANRDPDARIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFD KYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVVVSRSEIDL FNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD >XP_012034784.2 annexin A5 isoform X2 [Ovis aries] MAQVLRGTVTDFPGFNERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLK SELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDD VVGDTSGYYQRMLVVLLQANRDPDARIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVF DKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVVVSRSEID LYNIRKEFRKNFGTSLYSMIKGDTSGDYKKTLLLLCGGEDD >XP_004040389.1 annexin A5 [Gorilla gorilla gorilla] MAQILRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLK SELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDD VVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRKVF DKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEID LFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGEDD >XP_013225254.2 annexin A5 isoform X1 [Columba livia] MNTRGTVTAFSPFDARADAEALRKAMKGMGTDEETVMKILTSRNNAQRQEIASAFKTLFGRDLVDDLKSE LTGKFETLMVSLMRPAYIFDAHALKHAIKGAGTNEKVLTEILASRTPAEVRQIKQVYLQEYEANLEDKIT GETSGHFQRLLVVLLQANRDPDGRVDEGLVEQDAQVLFRAGELKWGTDEEKFITILGTRSVSHLRRVFDK YMTISGFQIEETIDRETSGDLEKLLLAVVKCIRSVPAYFAETLYYSMKGAGTDDDTLIRVMVSRSEIDLL DIRQELRKNFAKSLHQMIQKDTSGDYRKALLLLCGGDDA >XP_017904654.1 PREDICTED: annexin A5 [Capra hircus] MAQVLRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLK SELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDD VVGDTSGYYQRMLVVLLQANRDPDARIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVF DKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVVVSRSEID LYNIRKEFRKNFGTSLYSMIKGDTSGDYKKTLLLLCGGEDD >XP_006015678.1 annexin A5 [Alligator sinensis] MAKYSRGTVKDFSGFDARADAEALRKAMKGMGTDEETVLKILTSRSNAQRQEIAAAFKTLFGRDLVDDLK SELTGKFEKLMVSLMKPAQLFDAYELKHAIKGAGTNEKVLTEILASRTPAELRSIKQVYQEEYESDLEDK ITGETSGFFQRMLVVLLQANRDPDGRIDAGLVEQDAQVLFKAGELKWGTDEEKFITILGTRSVSHLRKVF DKYMTISGFQIEETIDRETSGDLEKLLLAVVKCVRNVPAYFAECLFYSMKGAGTDDDTLIRIMVSRSEID MLDIRRELRKNFAKSLYQMIQKDTSGDYRKALLLLCGGEDD >XP_006263490.1 PREDICTED: annexin A5 isoform X1 [Alligator mississippiensis] MAKYSRGTVKDFSGFDARADAEALRKAMKGMGTDEETVLKILTSRSNAQRQEIAAAFKTLFGRDLVDDLK SELTGKFEKLMVSLMKPAQLFDAYELKHAIKGAGTNEKVLTEILASRTPAELRSIKQVYQEEYESDLEDK ITGETSGFYQRMLVVLLQANRDPDGRIDAGLVEQDAQVLFKAGELKWGTDEEKFITILGTRSVSHLQKVF DKYMTISGFQIEETIDRETSGDLEKLLLAVVKCVRNVPAYFAECLFYSMKGAGTDDDTLIRIMVSRSEID MLDIRRELRKNFAKSLYQMIQKDTSGDYRKALLLLCGGEDD >XP_020763968.1 annexin A5 [Odocoileus virginianus texanus] MAQVLRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLK SELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDD VVGDTSGYYQRMLVVLLQANRDPDTRIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVF DKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVVVSRSEID LYNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD >XP_040186261.1 annexin A5 [Rana temporaria] MATTNRGTIKAFPGFKANDDAEALRKAMKGLGTDEDPIMKILTSRSNAQRQQIDVAFKTLFGRDLVDDLK SELTGKLEKVVVALMTPANMYDAQQLRYATKGAGTTENVLAEILASRSTPEIHHINKVYKEEHGCELEDC ITGDTSGYFQRMLVVLAQGNRDPDSKVNDALVEQDAQDLFKAGETKWGTDEEKFITILGTRSNAHLRKVF DRYMTISGYQIEESIDRETSGNLEKLLLAIVKNVRCVPGYFAETLFRAMKGAGTDDDTLIRVMVSRSEID MLDIRKEYRKHYGKSLYQAIKCDTSGDYRNTLLLICGGDDE >XP_043294252.1 annexin A5 isoform X1 [Cervus canadensis] MASSLHEGQTFPGALGSRDPSVLQSSGGQAPPRRRGLRAAAAHAGALRPEAVGGAQGRCGPRPAGLGWAGPDRAAVFPLP GAASKQRPQRPPLTLAGSARPAAFPAVRVWSCVAHLLLTWAGAMAQVLRGTVTDFPGFDERADAETLRKAMKGLGTDEES ILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASR TPEELRAIKKVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDTRIDEAQVEQDAQALFQAGELKWGTDEEKFITI FGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRS EIDLYNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD >XP_043726893.1 annexin A5 isoform X1 [Cervus elaphus] MFQSSGGRAPPRRRGLGAAAAHAGALRPEAVGGAQGRCGPRPAGLGWAGPDRAAVFPLPGAASKQRPQRPPLTLAGSARP AAFPAVRVWSCVAHLLLTWAGAMAQVLRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFK TLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKKVYEEEYGSSLE DDVVGDTSGYYQRMLVVLLQANRDPDTRIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDKYMTISG FQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVVVSRSEIDLYNIRKEFRKNFATSLYS MIKGDTSGDYKKALLLLCGGEDD >KAF4019674.1 hypothetical protein G4228_011601 [Cervus hanglu yarkandensis] MFPCQVLRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLKSELTGKFE KLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKKVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQ ANRDPDTRIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLL AVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLYNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGG EDD >NP_001085335.1 annexin A5 S homeolog [Xenopus laevis] MAFKSKSRGTIKDFPGFKANDDAETLRKAMKGLGTDEESIIKILISRSNAQRQEVAVAFKTLFGRDLVDDLKSELSGKFE KLIVALMIPDALYDAYELRHAMKGAGTCENVLIEILASRTTGEVKHIKQVYQQEYGRELEDSITGDTSGYFQRMLVVLVQ ANRDPDSKVNDSLVEQDAQDLFKAGELKWGTDEEKFITILGTRSISHLRKVFDKYMTISGYQIEESIGRETSGHLEKLLL AVVKSVRSIPEYLAETLYHAMKGAGTDDCTLIRVMVSRSEVDLLDIREKFRKNWGKSLHAMIKGDTSGDYRNALLLICGG DDD >KAB0380453.1 hypothetical protein FD755_008237 [Muntiacus reevesi] MARVLRGTVTDFPGFDGRADAGTLRKAMKGLGTDEGSILTLLTSRSNAQRPEIAVAFRGLLDDLKSELTGKCENLIVALM KPSRLYDAYELKHALKGAGANEKVLTEIIASRTPEGLRAIKQAYEEEYGPSLEDDVVGDPSAQVEQNAQALFQAGELKWG TDEEKLITIFGTRRFQIEETIDRETSGNLEHLLLAVVKSIRSIPAYLAETLYYAMKGAGTDERTLIRVVVSRSEIDLYNI RKEFRKNFATSLYSMIKGDTSGDYKKALLLLRGGEDD >XP_015797977.1 PREDICTED: annexin A5-like [Nothobranchius furzeri] MAFRGTVKASANFKASADAEVLHKAMKGLGTDEAAILQLLTARSNAQRQEIKASYKTLFGKDLVHDLKGELGGKFETLVV ALMTPPLTYDVTSLHHAIKGAGTDEKVLVEILASRTPQQVKDIIAAYKTEYDHDLEKDICGDTSGHFQRLLVILLQASRQ TGIQEANIESDAQALFKAGEQKYGTDEQSFITILGNRSAEHLRKVFDAYTKLSGYEMEESIKRETSGSLRALLLAVVKCA RSVPSYFAETLYYAMKGAGTDDDTLIRVMVTRCEVDMLDIRAAFRRMFACSLHSMIKGDTNGDYRKTLLLLCGGDDA >NP_001098345.1 annexin A10 [Oryzias latipes] MASKGTVKAAANFKASADAEVLHKAMKGIGTDEDAILQLVCARSNAQRQEIKATYKTLFGKDLINDLKSELGGKFETLIV ALMTPPTAYDVVSLRNAIKGAGTDEKVLVEILASRTPQQVKDIIAAYRKEYDADLEEDICGDTSGHFKRLLVILLQANRQ TGVQEGDIENDAQVLFKAGEQKFGTDEQTFVTLLGNRSAQHLRKVFDAYMKLSGYEIEESIKRETSGSLKDLLLAVVKCA RSVPAYFAETLYNAMKGAGTDDDTLIRVMVTRGEVDMLDIRAEFRKLFARSLFSMIKGDTGGDYRKALLLLCGGDDA >XP_030286668.1 annexin A10 [Sparus aurata] MASRGTVKASGNFNASADAEALYKSMKGLGTDEDTILQLLTARSNSQRQEIKATYKTLFGKDLVDDLKGELGGKFETLIV GLMTPPLAYDVTLLRNAIKGAGTDEKVLVEVLASRTCQQVKDIVGAYRQEYDDDLEEDVSGDTSGHFKRLLVILLQANRQ KGIQEGTVESDAQVLFQAGEKKFGTDEQTFVTILGNRSAEHLRKVFDAYMKLSGYEMEESIKRETSGPLRDLLLAVVKCA RSVPAYFAETLYYAMKGAGTDDETLIRVMVSRSEVDMMDIRAEFRRMFPSSLFSMIKGDTGGDYRKALLLLCGGDDA >XP_026296548.1 annexin B9 [Apis mellifera] MSQQQYYPFKCTPTVYPAEPFDANADAALLRKAMKGFGTDEKTIIDVLTRRGIVQRLEVAEAYKTLYGKDLISDLKSELT GKLEDVIIALMTPLPHYYAKELHDAVSGLGTDEEAIVEILCTLSNYGIRTIAAFYENLYGKSLESDLKGDTSGHFKRLLV SLVQANRDENQGIDQTQAIADAQALYEAGEKQWGTDESQFNAILVTRSYQQLRQTFIEYEKISGHDIEVAIKKEFSGNLE KGLLGIVKCVKSKVGFFAERLYASMHGIGTKDRTLIRIIVSRSEIDLGDIKKAFEERYGKSLESWIAGDTSGDYKKALLS LVST >XP_030834955.1 annexin A5 isoform X1 [Strongylocentrotus purpuratus] MSYPGYPPAGAPGYPPAGQPGYPLLLAPTRQQEGLQVTLLQGSQVTPLQPPATQQVQLHPQLEGNPMEQLQDTLLQGELV TPCARLWRLSLCPATCTRLWCPTRRSPGIPPAGGYPAAGGYPGQQPPAAGYPGQQPPPAAGYPGQQPPPAAGYPGQQPPP AGYGQPPAAGYPQQPPAAGYPGAAPAAYAAGGAPGYPSQPAGAQPPPPSGQQLYGAAGATVVATGLAAQYAQEKPKPMAP PAVQEPVTSQLSRMALTDQPFETHGTVRPHHPFDAEQDASVLRKAMKGMGTDEKAIINLLATRSNAQRQTIKLQFKTMYG KDLIHDLKSELSGKLEDLILAMFVPGPQYDAYAINKAIKGLGTDEEILIEILCTRTNKEIHEINEEYKKQFRTTMEKDCI GDTSGHFKRLLVSMCQGNRDESSTVDMAKAQAEANALYQAGEKKWGTDESEFNRILATRNFAQLRATFKEYTRIAQRDLL NSIEREFSGNIKNGLKTIVQCTQSRPSYFADRAYRAMKGAGTDDDTLIRVIVTRSEIDLVEIKKAFLEKYHKTLGKMVSG DTSGDYKKLLVALIGQD >XP_031556011.1 annexin-B12-like isoform X2 [Actinia tenebrosa] MSYGPPWNYGMPQPGAPPFPMQQGGAPPPLGFDHVLSSPSGPAGVGGMPMPMAQPSMPYQAMPTQSGPGMPLPGAMSYPT PGYGPAPPASPAPMGHYPNQNLTFGTTYYHEETSYSTQSTVASAPPLQTMASSVLCSSKPSSRGRPSVTAYSPFDGKKDA EVLRKAMKGLGCDNKAITYLLCSRTNAQRQRISIEYKTIYGRDLMKDLKSELGGHFEDTVIALMTPPEEYDATLIRKALK GLGTNEEILIEILSTRTNNELVAIKNAYQRLFERDMEKDIAGDTSGHFKKFLISLAQAYREETDQVDIHKARASAEALYK AGEGRWGTDEAKFNSVLASKSFPQLRAVFDEYSKICKYDIEESIRREMSGDLKDGMVSIVQVVRNAPGFFAQKLYKSMKG LGTDDKALIRVVVTRSEIDILDIKDEFAKQYGQSLAQFIADDTKGNYKRILLQLIGESA >XP_039270557.1 annexin A4-like isoform X2 [Styela clava] MSYGYPYQQGGAPPPGGGYPPQPQGYPPQGGYPPQQGGYPPQGGYPPAPGGPAYPPGPGGPGYPPAPGGAPGYPPAPGYP PAAGGYPQPGAPGAYPPPGQSSGLGFDALAGPPQPAAQSYGQPPGGYGYGAPPAPGGYPPAAGYPPQAQQAYGAQPAAGY HPPAGYGAPGPSHKMSNPQQLAAGMAAMTIATHGTVKAYPSFNAEEDAKILRKAMKGIGTDEKSIINVIGHRNNKQRQDI IIAYKQAYGKDLIKDLKSELSGNFESLVKAMFMKPRHYDVYCLERSMSGIGTDESALIEIFTSRSNAEIKEIKEIFKKER KKDLEKALKSETSGHFSRLLVSLCNASRNETTSVDQGKARADAQALYQAGEKKWGTDEATFNMIMCSRSIPQLRATFIEY HKIANRDISKSIEGEFSGDIEEGLKAVVETARSAPAYFAKRLYKSMSGAGTDDHTLIRIVVSRSEIDMVEIKQEFQRTYS KTLGSFIQGDTSGDYKNLLTTLVGP >CAE1230049.1 ANXA7_11 [Sepia pharaonis] MVVCHYHPRTPCGPFLFLTVDFMHGDSQVFMPDESILSKSANLFSAAAKVVTAAYIAFHLLGNMSYPYYGAGQNAPQNYP PNMGQQPNPSMGYPNFTGYDSTPNMQYSAQPSAGPGVIGFNIGMTNQGGYPNTQQGAYPPPAQQGAYPPPPQQGAYPPPA QQGSYPPPAQQGMYPPPQQQGAYPPTQRGMYPPPPQPGAYPPPPQQGSYPPVPGSSSPRPQHTAYPPQQQTVNPSQQEFY PASHQQQKGYFPSEQQTSHPIPSSRQNKPLKEEGTLKPYPGFNAETDAQILRKAMKGFGTDEKAIIDVLGSRSNEQRQDI VRMFKTIFGKDLIKELKSELSGNFETVVLGLLYTPSMYDATELKKAMQGLGTNEDVLIEIMCSRSNKEIMEISDCFKKIT GKSLENWLKSETSGHFCRLLVSLSTAGRSENQNVDLQSAEQDAKKLYEAGEKQWGTNESQFNAILASRSLPQLKAVFDAY KHLYNRDIEQVIASEMSGDLLSGMLSVVKVVKSKPCYFAERLYTSMKGAGTNDSTLIRVIISRCEIDMKQIKQEFQKMYG KTLDAMVKGDCSGDYCRILLRLLGNESY >XP_038060971.1 annexin A5-like [Patiria miniata] MSYGGYPPAPGGYPPAQGGYPPAPGGGGYPPAPGGGGYPPAAPGGGGYPGGGGYPSVPGGGGYPPAPAPGAGGYPPAPGG YPPAPGGGGYPPAPGGGGYPPAPAPGGYPPAMPQPGYPPAPQPAGYPTGAPVSMPSADYGASVGSAGLPYNPNPTSSMGF AGAAYAATAFRPPSASAFRQPAAPAPGGPPMPTPQYTPTPQYNPPPAQRAPAPQSAPGAQAPIVPTQQLASMSMAPKAVK RGTGTVKEKSNFDGHKEAEILRKAMKGIGTDEKAIIGVVTACSNAQRQRLLIDYKTMYGKDLVKNLKSELKSKLEEVVLD LMMTPALFDAHQLRKAMKGLGTDEAVLIEILCTRTNQEIVTIKEAYKKEFSRNLEKDVISETSGHFQRLLVSMTQGARRE DPTVDQAKAKADAKALWDAGEKKWGTDESQFNVILASRSFPQLRATFEEYSKLGKYSIEQSIKREMSGDLEKGMLTIVDC VRNTPKYFSDKLYKSMKGLGTDDDTLIRIIVSRCEIDMVEIKQEFHRDHKQTLGKFIAGDTSGDYKKILLELVGGES >NP_001262796.1 annexin B9, isoform E [Drosophila melanogaster] MSSAEYYPFKCTPTVYPADPFDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQRLEIAEAFKTSYGKDLISDLKSELG GKFEDVILALMTPLPQFYAQELHDAISGLGTDEEAIIEILCTLSNYGIKTIAQFYEQSFGKSLESDLKGDTSGHFKRLCV SLVQGNRDENQGVDEAAAIADAQALHDAGEGQWGTDESTFNSILITRSYQQLRQIFLEYENLSGNDIEKAIKREFSGSVE KGFLAIVKCCKSKIDYFSERLHDSMAGMGTKDKTLIRIIVSRSEIDLGDIKEAFQNKYGKSLESWIKGDTSGDYKRALLA IVGF >NP_001022756.1 Annexin [Caenorhabditis elegans] MNSGGGYPNQQPSYGGYGQPPQQPGYGNGSYDPYGQPQQQPYPGGGGQPPYPGSNSNQGGGGYPGQGGAPYPGGSGGYPQ APQYGFSGGQGSAPQPNQGGYPPQQQQYPPQQGYQQGGQQQGGGGFFPNQGYGQPVMIGTPSVFPVQGFNSNADAEVLRK AMKGLGCNNSKVISILCQRTNWQRQEISKAFKVMYGKDLIKELKGELHGDFEDLILALMDAPAIYDAKQLHRAMEGLGTK ESVLIEIMTSRTNAQIQQVRDAYKMLFKKDLERDLIGETSGHFKRLLVSLCAGGRDESSQTDGLRANQDARRLLQAGEKR LGTDESTFNAILASQNFSQLRLVFEEYQKASNHSIEKAIEFEFSGDIRDGLLAVIAVIRNRPAYFAKLLHDSMKGLGTRD NDLIRLCVTRAEYDMGDIRNMFQSLYRTSLENMIKGDCSGAYKEGLIALVNGNRG
Mafft alignment of selected proteins >sp|P08758|ANXA5_HUMAN Annexin A5 OS=Homo sapiens OX=9606 GN=ANXA5 PE=1 SV=2 ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MAQVLRGTVTDFPG FDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELT GKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYG SSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKF ITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAET LYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLL LCGEDD- >tr|Q6P0V8|Q6P0V8_DANRE Annexin OS=Danio rerio OX=7955 GN=anxa5b PE=1 SV=1 ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MAGRGTVKPQSG FNANSDAEVLYKAMKGLGTDEDSILQLLTKRSNGQRQEIKAAYKTLHGKDLVNDLKSELG GKFEDLIVALMTPPIIYEVTCLRNAIKGAGTDEKVLIEILASRSPNEVNEIKSSYKREHD KDLEEDVTGDTGGHFERMLVVLLQASR--QQGIQESLIQSDAQALFAAGEQKYGTDEGQF ITILGNRSNAHLRRVFEEYRKLSGFEIEESIQRETSGSLQEILLAVVKCARSVPGYFADS LYAAMKGAGTDDQTLIRIMVTRSEVDLLDIRAEFRKRFATSLHKMIQSDTSGDYRKTLLL LCGGDDA >NP_033803.1 annexin A5 [Mus musculus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MATRGTVTDFPG FDGRADAEVLRKAMKGLGTDEDSILNLLTSRSNAQRQEIAQEFKTLFGRDLVDDLKSELT GKFEKLIVAMMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELSAIKQVYEEEYG SNLEDDVVGDTSGYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKF ITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAET LYYAMKGAGTDDHTLIRVVVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLL LCGGEDD >NP_037264.2 annexin A5 [Rattus norvegicus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MALRGTVTDFSG FDGRADAEVLRKAMKGLGTDEDSILNLLTARSNAQRQQIAEEFKTLFGRDLVNDMKSELT GKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQVYEEEYG SNLEDDVVGDTSGYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKF ITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLENLLLAVVKSIRSIPAYLAET LYYAMKGAGTDDHTLIRVIVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLL LCGGEDD >NP_001035567.3 annexin A5 [Bos taurus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MAQVLRGTVADFPG FDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLKSELT GKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQVYEEEYG SSLEDDVVGDTSGYYQRMLVVLLQANRDPDARIDEAQVEQDAQALFQAGELKWGTDEEKF ITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAET LYYAMKGAGTDDHTLIRVVVSRSEIDLYNIRKEFRKNFGTSLYSMIKGDTSGDYKKALLL LCGGEDD >NP_001026709.1 annexin A5 [Gallus gallus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MAKYTRGTVTAFSP FDARADAEALRKAMKGMGTDEETILKILTSRNNAQRQEIASAFKTLFGRDLVDDLKSELT GKFETLMVSLMRPARIFDAHALKHAIKGAGTNEKVLTEILASRTPAEVQNIKQVYMQEYE ANLEDKITGETSGHFQRLLVVLLQANRDPDGRVDEALVEKDAQVLFRAGELKWGTDEETF ITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGDLEKLLLAVVKCIRSVPAYFAET LYYSMKGAGTDDDTLIRVMVSRSEIDLLDIRHEFRKNFAKSLYQMIQKDTSGDYRKALLL LCGGDDE >NP_001009099.1 annexin A5 [Pan troglodytes] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MAQVLRGTVTDFPG FDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELT GKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYG SSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKF ITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAET LYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLL LCGEDD- >NP_001301047.1 annexin A5 [Canis lupus familiaris] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MAQVLKGTVTPFPG FDERADAEVLRKAMKGLGTDEESILTLLTSRSNAQRQEIAAAFKTLFGRDLLDDLKSELT GKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYG SSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKF ITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAET LYYAMKGAGTDDHTLIRVVVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLM LCGGEDD >XP_008266130.1 PREDICTED: annexin A5 [Oryctolagus cuniculus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MAQALRGTVTAFPG FDERADAEILRKAMKGLGTDEDSILTLLTARSNGQRQEIADAFKTLYGRDLLDDLKSELT GKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPAELTAIKQVYEEEYG SSLEDDVMGDTSGYYQRMLVVLLQANRDPDSGIDTAQVEQDAQTLFQAGELKWGTDEEKF ITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAET LYYAMKGAGTDDHTLIRVMVSRSEIDLYNIRKEFRKNFGTSLYSMIKDDTSGDYKKALLL LCGGDDD >XP_002815150.2 annexin A5 [Pongo abelii] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MAQVLRGTVTDFPG FDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELT GKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYG SSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKF ITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAET LYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLL LCGEDD- >XP_003129266.2 annexin A5 [Sus scrofa] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MAQVLRGTVTDFPG FDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLKSELT GKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKILTEIIASRTPEELRAIKQVYEEEYG SSLEDDVVGDTSGYYQRMLVVLLQANRDPDGRIDEAQVEQDAQALFQAGELKWGTDEEKF ITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAET LYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLL LCGGEDD >XP_010708237.1 annexin A5 [Meleagris gallopavo] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MYTRGTVTAFSP FDARADAEALRKAMKGMGTDEETILKILTSRNNAQRQEIASAFKTLFGRDLVDDLKSELT GKFETLMVSLMRPARIFDAHALRHAIKGAGTNEKVLTEILASRTPAEVQNIKQVYMQEYE ANLEDKITGETSGHFQRLLVVLLQGNRDPDGRVDEALVEKDAQVLFRAGELKWGTDEETF ITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGDLEKLLLAVVKCIRSVPAYFAET LYYSMKGAGTDDDTLIRVMVSRSEIDLLDIRHEFRKNFAKSLHQMIQKDTSGDYRKALLL LCGGDDE >XP_003816466.1 annexin A5 [Pan paniscus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MAQVLRGTVTDFPG FDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELT GKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYG SSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKF ITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAET LYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLL LCGEDD- >XP_006930945.1 annexin A5 [Felis catus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MAQV-KGTVTPFPG FDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIATAFKTLFGRDLLDDLKSELT GKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYG SSLEDDVVGDTSGYYQRMLVVLLQANRDPDARIDEAQVEQDAQALFQAGELKWGTDEEKF ITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAET LYYAMKGAGTDDHTLIRVVVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLL LCGGEDD >XP_012034784.2 annexin A5 isoform X2 [Ovis aries] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MAQVLRGTVTDFPG FNERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLKSELT GKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQVYEEEYG SSLEDDVVGDTSGYYQRMLVVLLQANRDPDARIDEAQVEQDAQALFQAGELKWGTDEEKF ITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAET LYYAMKGAGTDDHTLIRVVVSRSEIDLYNIRKEFRKNFGTSLYSMIKGDTSGDYKKTLLL LCGGEDD >XP_004040389.1 annexin A5 [Gorilla gorilla gorilla] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MAQILRGTVTDFPG FDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELT GKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYG SSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKF ITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAET LYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLL LCGEDD- >XP_013225254.2 annexin A5 isoform X1 [Columba livia] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MNTRGTVTAFSP FDARADAEALRKAMKGMGTDEETVMKILTSRNNAQRQEIASAFKTLFGRDLVDDLKSELT GKFETLMVSLMRPAYIFDAHALKHAIKGAGTNEKVLTEILASRTPAEVRQIKQVYLQEYE ANLEDKITGETSGHFQRLLVVLLQANRDPDGRVDEGLVEQDAQVLFRAGELKWGTDEEKF ITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGDLEKLLLAVVKCIRSVPAYFAET LYYSMKGAGTDDDTLIRVMVSRSEIDLLDIRQELRKNFAKSLHQMIQKDTSGDYRKALLL LCGGDDA >XP_017904654.1 PREDICTED: annexin A5 [Capra hircus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MAQVLRGTVTDFPG FDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLKSELT GKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQVYEEEYG SSLEDDVVGDTSGYYQRMLVVLLQANRDPDARIDEAQVEQDAQALFQAGELKWGTDEEKF ITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAET LYYAMKGAGTDDHTLIRVVVSRSEIDLYNIRKEFRKNFGTSLYSMIKGDTSGDYKKTLLL LCGGEDD >XP_006015678.1 annexin A5 [Alligator sinensis] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MAKYSRGTVKDFSG FDARADAEALRKAMKGMGTDEETVLKILTSRSNAQRQEIAAAFKTLFGRDLVDDLKSELT GKFEKLMVSLMKPAQLFDAYELKHAIKGAGTNEKVLTEILASRTPAELRSIKQVYQEEYE SDLEDKITGETSGFFQRMLVVLLQANRDPDGRIDAGLVEQDAQVLFKAGELKWGTDEEKF ITILGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGDLEKLLLAVVKCVRNVPAYFAEC LFYSMKGAGTDDDTLIRIMVSRSEIDMLDIRRELRKNFAKSLYQMIQKDTSGDYRKALLL LCGGEDD >XP_006263490.1 PREDICTED: annexin A5 isoform X1 [Alligator mississippiensis] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MAKYSRGTVKDFSG FDARADAEALRKAMKGMGTDEETVLKILTSRSNAQRQEIAAAFKTLFGRDLVDDLKSELT GKFEKLMVSLMKPAQLFDAYELKHAIKGAGTNEKVLTEILASRTPAELRSIKQVYQEEYE SDLEDKITGETSGFYQRMLVVLLQANRDPDGRIDAGLVEQDAQVLFKAGELKWGTDEEKF ITILGTRSVSHLQKVFDKYMTISGFQIEETIDRETSGDLEKLLLAVVKCVRNVPAYFAEC LFYSMKGAGTDDDTLIRIMVSRSEIDMLDIRRELRKNFAKSLYQMIQKDTSGDYRKALLL LCGGEDD >XP_020763968.1 annexin A5 [Odocoileus virginianus texanus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MAQVLRGTVTDFPG FDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLKSELT GKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYG SSLEDDVVGDTSGYYQRMLVVLLQANRDPDTRIDEAQVEQDAQALFQAGELKWGTDEEKF ITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAET LYYAMKGAGTDDHTLIRVVVSRSEIDLYNIRKEFRKNFATSLYSMIKGDTSGDYKKALLL LCGGEDD >XP_040186261.1 annexin A5 [Rana temporaria] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MATTNRGTIKAFPG FKANDDAEALRKAMKGLGTDEDPIMKILTSRSNAQRQQIDVAFKTLFGRDLVDDLKSELT GKLEKVVVALMTPANMYDAQQLRYATKGAGTTENVLAEILASRSTPEIHHINKVYKEEHG CELEDCITGDTSGYFQRMLVVLAQGNRDPDSKVNDALVEQDAQDLFKAGETKWGTDEEKF ITILGTRSNAHLRKVFDRYMTISGYQIEESIDRETSGNLEKLLLAIVKNVRCVPGYFAET LFRAMKGAGTDDDTLIRVMVSRSEIDMLDIRKEYRKHYGKSLYQAIKCDTSGDYRNTLLL ICGGDDE >XP_043294252.1 annexin A5 isoform X1 [Cervus canadensis] M----------------------------------------------------------- ----ASSLHEGQ-----TFPGALGSRD----------------------------PSVLQ ------------------------------------------------------------ ----S--SGGQA-----------------------------PPRRRGLRAAAAHAGA-LR PEA--V------GGAQGRC---GPRPAGL------GWAG--------------------- ----PDRAAVF-------------------------PLPGAASKQRPQR---PPLTLAG- ----------------SARPAAFPAVRVWSCVAHLLLTWAGA----MAQVLRGTVTDFPG FDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLKSELT GKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKKVYEEEYG SSLEDDVVGDTSGYYQRMLVVLLQANRDPDTRIDEAQVEQDAQALFQAGELKWGTDEEKF ITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAET LYYAMKGAGTDDHTLIRVMVSRSEIDLYNIRKEFRKNFATSLYSMIKGDTSGDYKKALLL LCGGEDD >XP_043726893.1 annexin A5 isoform X1 [Cervus elaphus] ------------------------------------------------------------ ---------------------------------------------------------MFQ ------------------------------------------------------------ ----S--SGGRA-----------------------------PPRRRGLGAAAAHAGA-LR PEA--V------GGAQGRC---GPRPAGL------GWAG--------------------- ----PDRAAVF-------------------------PLPGAASKQRPQR---PPLTLAG- ----------------SARPAAFPAVRVWSCVAHLLLTWAGA----MAQVLRGTVTDFPG FDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLKSELT GKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKKVYEEEYG SSLEDDVVGDTSGYYQRMLVVLLQANRDPDTRIDEAQVEQDAQALFQAGELKWGTDEEKF ITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAET LYYAMKGAGTDDHTLIRVVVSRSEIDLYNIRKEFRKNFATSLYSMIKGDTSGDYKKALLL LCGGEDD >KAF4019674.1 hypothetical protein G4228_011601 [Cervus hanglu yarkandensis] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------MF------------------------------------------------- ----------------------------------------------PCQVLRGTVTDFPG FDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLKSELT GKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKKVYEEEYG SSLEDDVVGDTSGYYQRMLVVLLQANRDPDTRIDEAQVEQDAQALFQAGELKWGTDEEKF ITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAET LYYAMKGAGTDDHTLIRVMVSRSEIDLYNIRKEFRKNFATSLYSMIKGDTSGDYKKALLL LCGGEDD >NP_001085335.1 annexin A5 S homeolog [Xenopus laevis] M----------------------------------------------------------- ----A------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------FKSKSRGTIKDFPG FKANDDAETLRKAMKGLGTDEESIIKILISRSNAQRQEVAVAFKTLFGRDLVDDLKSELS GKFEKLIVALMIPDALYDAYELRHAMKGAGTCENVLIEILASRTTGEVKHIKQVYQQEYG RELEDSITGDTSGYFQRMLVVLVQANRDPDSKVNDSLVEQDAQDLFKAGELKWGTDEEKF ITILGTRSISHLRKVFDKYMTISGYQIEESIGRETSGHLEKLLLAVVKSVRSIPEYLAET LYHAMKGAGTDDCTLIRVMVSRSEVDLLDIREKFRKNWGKSLHAMIKGDTSGDYRNALLL ICGGDDD >KAB0380453.1 hypothetical protein FD755_008237 [Muntiacus reevesi] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------MARVLRGTVTDFPG FDGRADAGTLRKAMKGLGTDEGSILTLLTSRSNAQRPEIAVAF-----RGLLDDLKSELT GKCENLIVALMKPSRLYDAYELKHALKGAGANEKVLTEIIASRTPEGLRAIKQAYEEEYG PSLEDDVVGDPS-----------------------AQVEQNAQALFQAGELKWGTDEEKL ITIFGTRR----------------FQIEETIDRETSGNLEHLLLAVVKSIRSIPAYLAET LYYAMKGAGTDERTLIRVVVSRSEIDLYNIRKEFRKNFATSLYSMIKGDTSGDYKKALLL LRGGEDD >XP_015797977.1 PREDICTED: annexin A5-like [Nothobranchius furzeri] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MAFRGTVKASAN FKASADAEVLHKAMKGLGTDEAAILQLLTARSNAQRQEIKASYKTLFGKDLVHDLKGELG GKFETLVVALMTPPLTYDVTSLHHAIKGAGTDEKVLVEILASRTPQQVKDIIAAYKTEYD HDLEKDICGDTSGHFQRLLVILLQASR--QTGIQEANIESDAQALFKAGEQKYGTDEQSF ITILGNRSAEHLRKVFDAYTKLSGYEMEESIKRETSGSLRALLLAVVKCARSVPSYFAET LYYAMKGAGTDDDTLIRVMVTRCEVDMLDIRAAFRRMFACSLHSMIKGDTNGDYRKTLLL LCGGDDA >NP_001098345.1 annexin A10 [Oryzias latipes] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MASKGTVKAAAN FKASADAEVLHKAMKGIGTDEDAILQLVCARSNAQRQEIKATYKTLFGKDLINDLKSELG GKFETLIVALMTPPTAYDVVSLRNAIKGAGTDEKVLVEILASRTPQQVKDIIAAYRKEYD ADLEEDICGDTSGHFKRLLVILLQANR--QTGVQEGDIENDAQVLFKAGEQKFGTDEQTF VTLLGNRSAQHLRKVFDAYMKLSGYEIEESIKRETSGSLKDLLLAVVKCARSVPAYFAET LYNAMKGAGTDDDTLIRVMVTRGEVDMLDIRAEFRKLFARSLFSMIKGDTGGDYRKALLL LCGGDDA >XP_030286668.1 annexin A10 [Sparus aurata] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------MASRGTVKASGN FNASADAEALYKSMKGLGTDEDTILQLLTARSNSQRQEIKATYKTLFGKDLVDDLKGELG GKFETLIVGLMTPPLAYDVTLLRNAIKGAGTDEKVLVEVLASRTCQQVKDIVGAYRQEYD DDLEEDVSGDTSGHFKRLLVILLQANR--QKGIQEGTVESDAQVLFQAGEKKFGTDEQTF VTILGNRSAEHLRKVFDAYMKLSGYEMEESIKRETSGPLRDLLLAVVKCARSVPAYFAET LYYAMKGAGTDDETLIRVMVSRSEVDMMDIRAEFRRMFPSSLFSMIKGDTGGDYRKALLL LCGGDDA >XP_026296548.1 annexin B9 [Apis mellifera] M----------------------------------------------------------- ----SQ------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------QQYYPFKCTPTVYPAEP FDANADAALLRKAMKGFGTDEKTIIDVLTRRGIVQRLEVAEAYKTLYGKDLISDLKSELT GKLEDVIIALMTPLPHYYAKELHDAVSGLGTDEEAIVEILCTLSNYGIRTIAAFYENLYG KSLESDLKGDTSGHFKRLLVSLVQANRDENQGIDQTQAIADAQALYEAGEKQWGTDESQF NAILVTRSYQQLRQTFIEYEKISGHDIEVAIKKEFSGNLEKGLLGIVKCVKSKVGFFAER LYASMHGIGTKDRTLIRIIVSRSEIDLGDIKKAFEERYGKSLESWIAGDTSGDYKKALLS LVST--- >XP_030834955.1 annexin A5 isoform X1 [Strongylocentrotus purpuratus] M----------------------------------------------------------- ----SYPGYPPAGAP--GYPPA-GQPGYPLLLAPTRQQEGLQVTLLQGSQVTPLQPPATQ QVQLHPQLEGNPMEQLQDTLLQGELVTPCARLWRLSLCPATCTRLWCPTRRSPGIPPAGG YPAA----GGYPGQQPPAAGYPGQQPPPAAGYP--GQQP--PPAAGYPGQQPPPAGY-GQ PPAA---------GYPQQP----PAAGYPGAA-PAAYAAG-------------------- ------------------------------------GAPGYPSQP-AGAQPPPPSGQQLY GAAGATVVATGLAAQYAQEKPKPMAPPAVQEPVTSQLSRMA--LTDQPFETHGTVRPHHP FDAEQDASVLRKAMKGMGTDEKAIINLLATRSNAQRQTIKLQFKTMYGKDLIHDLKSELS GKLEDLILAMFVPGPQYDAYAINKAIKGLGTDEEILIEILCTRTNKEIHEINEEYKKQFR TTMEKDCIGDTSGHFKRLLVSMCQGNRDESSTVDMAKAQAEANALYQAGEKKWGTDESEF NRILATRNFAQLRATFKEYTRIAQRDLLNSIEREFSGNIKNGLKTIVQCTQSRPSYFADR AYRAMKGAGTDDDTLIRVIVTRSEIDLVEIKKAFLEKYHKTLGKMVSGDTSGDYKKLLVA LIGQD-- >XP_031556011.1 annexin-B12-like isoform X2 [Actinia tenebrosa] M----------------------------------------------------------- ----SYG------------------------------------------------PPWN- ------------------------------------------------------------ --------YGMP--QPGAPPFPM-------------QQGGAPPPLGFDHVLSSPSG---- -PAGV---------------GGMPMPMAQPSM---------------------------- -PYQAMPTQSG----------------------PGMPLPGAMSYPTPGYGPAPPASPAPM GHYPNQNLTFGTTYYHEETSYSTQSTVASAPPLQTMASSVLC-SSKPSSRGRPSVTAYSP FDGKKDAEVLRKAMKGLGCDNKAITYLLCSRTNAQRQRISIEYKTIYGRDLMKDLKSELG GHFEDTVIALMTPPEEYDATLIRKALKGLGTNEEILIEILSTRTNNELVAIKNAYQRLFE RDMEKDIAGDTSGHFKKFLISLAQAYREETDQVDIHKARASAEALYKAGEGRWGTDEAKF NSVLASKSFPQLRAVFDEYSKICKYDIEESIRREMSGDLKDGMVSIVQVVRNAPGFFAQK LYKSMKGLGTDDKALIRVVVTRSEIDILDIKDEFAKQYGQSLAQFIADDTKGNYKRILLQ LIGESA- >XP_039270557.1 annexin A4-like isoform X2 [Styela clava] M----------------------------------------------------------- ----SYG-YPYQQG---GAPPP--GGGYP----PQPQ--GY--------------PPQ-- ------------------------------------------------------------ --------GGYP---PQQGGYPP-----QGGYPPAPGGPAYPPGPGGPGYPPAPGGAPGY PPAP---------GYPPAA-GGYPQPGAPGAYPPPGQSSG-------------LGFDALA GPPQPAAQSYG------------QPPGGYGYGAP--PAPGGYP-PAAGY---PPQAQQA- --YGAQPAAG----YHPPAGYGAPGPSHKMSNPQQLAAGMAA----MTIATHGTVKAYPS FNAEEDAKILRKAMKGIGTDEKSIINVIGHRNNKQRQDIIIAYKQAYGKDLIKDLKSELS GNFESLVKAMFMKPRHYDVYCLERSMSGIGTDESALIEIFTSRSNAEIKEIKEIFKKERK KDLEKALKSETSGHFSRLLVSLCNASRNETTSVDQGKARADAQALYQAGEKKWGTDEATF NMIMCSRSIPQLRATFIEYHKIANRDISKSIEGEFSGDIEEGLKAVVETARSAPAYFAKR LYKSMSGAGTDDHTLIRIVVSRSEIDMVEIKQEFQRTYSKTLGSFIQGDTSGDYKNLLTT LVGP--- >CAE1230049.1 ANXA7_11 [Sepia pharaonis] MVVCHYHPRTPCGPFLFLTVDFMHGDSQVFMPDESILSKSANLFSAAAKVVTAAYIAFHL LGNMSYPYYGAGQNAPQNYPPNMGQQPNPSM--GYPNFTGYDST-----------PNMQY --------SAQP----------------------------------------SAGPGVIG FNIGMTNQGGYPN--TQQGAYPP--PAQQGAYPPPPQQGAYPPPAQQGSYPPPAQQG-MY PPPQQQ------GAYPPTQRGMYPPPPQPGAY---------------------------- -PPPPQQGSY-----------------------P--PVPGS-SSPRPQHTAYPPQQQTV- --NPSQQEF---------YPASHQQQKGYFPSEQQTSHPIPSSRQNKPLKEEGTLKPYPG FNAETDAQILRKAMKGFGTDEKAIIDVLGSRSNEQRQDIVRMFKTIFGKDLIKELKSELS GNFETVVLGLLYTPSMYDATELKKAMQGLGTNEDVLIEIMCSRSNKEIMEISDCFKKITG KSLENWLKSETSGHFCRLLVSLSTAGRSENQNVDLQSAEQDAKKLYEAGEKQWGTNESQF NAILASRSLPQLKAVFDAYKHLYNRDIEQVIASEMSGDLLSGMLSVVKVVKSKPCYFAER LYTSMKGAGTNDSTLIRVIISRCEIDMKQIKQEFQKMYGKTLDAMVKGDCSGDYCRILLR LLGNESY >XP_038060971.1 annexin A5-like [Patiria miniata] M----------------------------------------------------------- ----SYGGYPPAPG---GYPPA--QGGYP----PAPGGGGY--------------PPA-- -----PGGGGYP----------------------------------------PAAPGGGG YPGG----GGYPS-VPGGGGYPPAPAPGAGGYP--PAPGGYPPAPGGGGYPPAPGGG-GY PPAPAP------GGYPPAM----PQPGYPPAPQPAGYPTGAPVSMPSADYGASVGSAGL- -PYNPNPTSSMGFAGAAYAATAFRPPSASAFRQPAAPAPGGPPMPTPQYTPTPQYNP--- --PPAQRAP---------APQSAPGAQAPIVPTQQLASMSM--APKAVKRGTGTVKEKSN FDGHKEAEILRKAMKGIGTDEKAIIGVVTACSNAQRQRLLIDYKTMYGKDLVKNLKSELK SKLEEVVLDLMMTPALFDAHQLRKAMKGLGTDEAVLIEILCTRTNQEIVTIKEAYKKEFS RNLEKDVISETSGHFQRLLVSMTQGARREDPTVDQAKAKADAKALWDAGEKKWGTDESQF NVILASRSFPQLRATFEEYSKLGKYSIEQSIKREMSGDLEKGMLTIVDCVRNTPKYFSDK LYKSMKGLGTDDDTLIRIIVSRCEIDMVEIKQEFHRDHKQTLGKFIAGDTSGDYKKILLE LVGGES- >NP_001262796.1 annexin B9, isoform E [Drosophila melanogaster] M----------------------------------------------------------- ----SS------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------AEYYPFKCTPTVYPADP FDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQRLEIAEAFKTSYGKDLISDLKSELG GKFEDVILALMTPLPQFYAQELHDAISGLGTDEEAIIEILCTLSNYGIKTIAQFYEQSFG KSLESDLKGDTSGHFKRLCVSLVQGNRDENQGVDEAAAIADAQALHDAGEGQWGTDESTF NSILITRSYQQLRQIFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCCKSKIDYFSER LHDSMAGMGTKDKTLIRIIVSRSEIDLGDIKEAFQNKYGKSLESWIKGDTSGDYKRALLA IVGF--- >NP_001022756.1 Annexin [Caenorhabditis elegans] M----------------------------------------------------------- ----NSG----------------------------------------------------- ------------------------------------------------------------ --------GGYPNQQPSYGGYGQ--PPQQPGY----GNGSYDP-YGQPQQQPYPGGG-GQ PPYPGSNSNQGGGGYPGQ--GGAPYPGGSGGY---------------------------- -PQAPQYGFSG----------------------------GQGSAPQPNQGGYPPQQQQ-- --YPPQQGY---------QQGGQQQGGGGFFPNQG--------YGQPVMIGTPSVFPVQG FNSNADAEVLRKAMKGLGCNNSKVISILCQRTNWQRQEISKAFKVMYGKDLIKELKGELH GDFEDLILALMDAPAIYDAKQLHRAMEGLGTKESVLIEIMTSRTNAQIQQVRDAYKMLFK KDLERDLIGETSGHFKRLLVSLCAGGRDESSQTDGLRANQDARRLLQAGEKRLGTDESTF NAILASQNFSQLRLVFEEYQKASNHSIEKAIEFEFSGDIRDGLLAVIAVIRNRPAYFAKL LHDSMKGLGTRDNDLIRLCVTRAEYDMGDIRNMFQSLYRTSLENMIKGDCSGAYKEGLIA LVNGNRG
BMGE Cleaned alignment of selected proteins >sp|P08758|ANXA5_HUMAN Annexin A5 OS=Homo sapiens OX=9606 GN=ANXA5 PE=1 SV=2 LRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGEDD- >tr|Q6P0V8|Q6P0V8_DANRE Annexin OS=Danio rerio OX=7955 GN=anxa5b PE=1 SV=1 GRGTVKPQSGFNANSDAEVLYKAMKGLGTDEDSILQLLTKRSNGQRQEIKAAYKTLHGKDLVNDLKSELGGKFEDLIVALMTPPIIYEVTCLRNAIKGAGTDEKVLIEILASRSPNEVNEIKSSYKREHDKDLEEDVTGDTGGHFERMLVVLLQASR--QQGIQESLIQSDAQALFAAGEQKYGTDEGQFITILGNRSNAHLRRVFEEYRKLSGFEIEESIQRETSGSLQEILLAVVKCARSVPGYFADSLYAAMKGAGTDDQTLIRIMVTRSEVDLLDIRAEFRKRFATSLHKMIQSDTSGDYRKTLLLLCGGDDA >NP_033803.1 annexin A5 [Mus musculus] TRGTVTDFPGFDGRADAEVLRKAMKGLGTDEDSILNLLTSRSNAQRQEIAQEFKTLFGRDLVDDLKSELTGKFEKLIVAMMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELSAIKQVYEEEYGSNLEDDVVGDTSGYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVVVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD >NP_037264.2 annexin A5 [Rattus norvegicus] LRGTVTDFSGFDGRADAEVLRKAMKGLGTDEDSILNLLTARSNAQRQQIAEEFKTLFGRDLVNDMKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQVYEEEYGSNLEDDVVGDTSGYYQRMLVVLLQANRDPDTAIDDAQVELDAQALFQAGELKWGTDEEKFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLENLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVIVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD >NP_001035567.3 annexin A5 [Bos taurus] LRGTVADFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDARIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVVVSRSEIDLYNIRKEFRKNFGTSLYSMIKGDTSGDYKKALLLLCGGEDD >NP_001026709.1 annexin A5 [Gallus gallus] TRGTVTAFSPFDARADAEALRKAMKGMGTDEETILKILTSRNNAQRQEIASAFKTLFGRDLVDDLKSELTGKFETLMVSLMRPARIFDAHALKHAIKGAGTNEKVLTEILASRTPAEVQNIKQVYMQEYEANLEDKITGETSGHFQRLLVVLLQANRDPDGRVDEALVEKDAQVLFRAGELKWGTDEETFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGDLEKLLLAVVKCIRSVPAYFAETLYYSMKGAGTDDDTLIRVMVSRSEIDLLDIRHEFRKNFAKSLYQMIQKDTSGDYRKALLLLCGGDDE >NP_001009099.1 annexin A5 [Pan troglodytes] LRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGEDD- >NP_001301047.1 annexin A5 [Canis lupus familiaris] LKGTVTPFPGFDERADAEVLRKAMKGLGTDEESILTLLTSRSNAQRQEIAAAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVVVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLMLCGGEDD >XP_008266130.1 PREDICTED: annexin A5 [Oryctolagus cuniculus] LRGTVTAFPGFDERADAEILRKAMKGLGTDEDSILTLLTARSNGQRQEIADAFKTLYGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPAELTAIKQVYEEEYGSSLEDDVMGDTSGYYQRMLVVLLQANRDPDSGIDTAQVEQDAQTLFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLYNIRKEFRKNFGTSLYSMIKDDTSGDYKKALLLLCGGDDD >XP_002815150.2 annexin A5 [Pongo abelii] LRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGEDD- >XP_003129266.2 annexin A5 [Sus scrofa] LRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKILTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDGRIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD >XP_010708237.1 annexin A5 [Meleagris gallopavo] TRGTVTAFSPFDARADAEALRKAMKGMGTDEETILKILTSRNNAQRQEIASAFKTLFGRDLVDDLKSELTGKFETLMVSLMRPARIFDAHALRHAIKGAGTNEKVLTEILASRTPAEVQNIKQVYMQEYEANLEDKITGETSGHFQRLLVVLLQGNRDPDGRVDEALVEKDAQVLFRAGELKWGTDEETFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGDLEKLLLAVVKCIRSVPAYFAETLYYSMKGAGTDDDTLIRVMVSRSEIDLLDIRHEFRKNFAKSLHQMIQKDTSGDYRKALLLLCGGDDE >XP_003816466.1 annexin A5 [Pan paniscus] LRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGEDD- >XP_006930945.1 annexin A5 [Felis catus] -KGTVTPFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIATAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDARIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVVVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD >XP_012034784.2 annexin A5 isoform X2 [Ovis aries] LRGTVTDFPGFNERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDARIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVVVSRSEIDLYNIRKEFRKNFGTSLYSMIKGDTSGDYKKTLLLLCGGEDD >XP_004040389.1 annexin A5 [Gorilla gorilla gorilla] LRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEISAAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDAGIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLFNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGEDD- >XP_013225254.2 annexin A5 isoform X1 [Columba livia] TRGTVTAFSPFDARADAEALRKAMKGMGTDEETVMKILTSRNNAQRQEIASAFKTLFGRDLVDDLKSELTGKFETLMVSLMRPAYIFDAHALKHAIKGAGTNEKVLTEILASRTPAEVRQIKQVYLQEYEANLEDKITGETSGHFQRLLVVLLQANRDPDGRVDEGLVEQDAQVLFRAGELKWGTDEEKFITILGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGDLEKLLLAVVKCIRSVPAYFAETLYYSMKGAGTDDDTLIRVMVSRSEIDLLDIRQELRKNFAKSLHQMIQKDTSGDYRKALLLLCGGDDA >XP_017904654.1 PREDICTED: annexin A5 [Capra hircus] LRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTDEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDARIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVVVSRSEIDLYNIRKEFRKNFGTSLYSMIKGDTSGDYKKTLLLLCGGEDD >XP_006015678.1 annexin A5 [Alligator sinensis] SRGTVKDFSGFDARADAEALRKAMKGMGTDEETVLKILTSRSNAQRQEIAAAFKTLFGRDLVDDLKSELTGKFEKLMVSLMKPAQLFDAYELKHAIKGAGTNEKVLTEILASRTPAELRSIKQVYQEEYESDLEDKITGETSGFFQRMLVVLLQANRDPDGRIDAGLVEQDAQVLFKAGELKWGTDEEKFITILGTRSVSHLRKVFDKYMTISGFQIEETIDRETSGDLEKLLLAVVKCVRNVPAYFAECLFYSMKGAGTDDDTLIRIMVSRSEIDMLDIRRELRKNFAKSLYQMIQKDTSGDYRKALLLLCGGEDD >XP_006263490.1 PREDICTED: annexin A5 isoform X1 [Alligator mississippiensis] SRGTVKDFSGFDARADAEALRKAMKGMGTDEETVLKILTSRSNAQRQEIAAAFKTLFGRDLVDDLKSELTGKFEKLMVSLMKPAQLFDAYELKHAIKGAGTNEKVLTEILASRTPAELRSIKQVYQEEYESDLEDKITGETSGFYQRMLVVLLQANRDPDGRIDAGLVEQDAQVLFKAGELKWGTDEEKFITILGTRSVSHLQKVFDKYMTISGFQIEETIDRETSGDLEKLLLAVVKCVRNVPAYFAECLFYSMKGAGTDDDTLIRIMVSRSEIDMLDIRRELRKNFAKSLYQMIQKDTSGDYRKALLLLCGGEDD >XP_020763968.1 annexin A5 [Odocoileus virginianus texanus] LRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKQVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDTRIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVVVSRSEIDLYNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD >XP_040186261.1 annexin A5 [Rana temporaria] NRGTIKAFPGFKANDDAEALRKAMKGLGTDEDPIMKILTSRSNAQRQQIDVAFKTLFGRDLVDDLKSELTGKLEKVVVALMTPANMYDAQQLRYATKGAGTTENVLAEILASRSTPEIHHINKVYKEEHGCELEDCITGDTSGYFQRMLVVLAQGNRDPDSKVNDALVEQDAQDLFKAGETKWGTDEEKFITILGTRSNAHLRKVFDRYMTISGYQIEESIDRETSGNLEKLLLAIVKNVRCVPGYFAETLFRAMKGAGTDDDTLIRVMVSRSEIDMLDIRKEYRKHYGKSLYQAIKCDTSGDYRNTLLLICGGDDE >XP_043294252.1 annexin A5 isoform X1 [Cervus canadensis] LRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKKVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDTRIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLYNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD >XP_043726893.1 annexin A5 isoform X1 [Cervus elaphus] LRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKKVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDTRIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVVVSRSEIDLYNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD >KAF4019674.1 hypothetical protein G4228_011601 [Cervus hanglu yarkandensis] LRGTVTDFPGFDERADAETLRKAMKGLGTDEESILTLLTSRSNAQRQEIAVAFKTLFGRDLLDDLKSELTGKFEKLIVALMKPSRLYDAYELKHALKGAGTNEKVLTEIIASRTPEELRAIKKVYEEEYGSSLEDDVVGDTSGYYQRMLVVLLQANRDPDTRIDEAQVEQDAQALFQAGELKWGTDEEKFITIFGTRSVSHLRRVFDKYMTISGFQIEETIDRETSGNLEQLLLAVVKSIRSIPAYLAETLYYAMKGAGTDDHTLIRVMVSRSEIDLYNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLCGGEDD >NP_001085335.1 annexin A5 S homeolog [Xenopus laevis] SRGTIKDFPGFKANDDAETLRKAMKGLGTDEESIIKILISRSNAQRQEVAVAFKTLFGRDLVDDLKSELSGKFEKLIVALMIPDALYDAYELRHAMKGAGTCENVLIEILASRTTGEVKHIKQVYQQEYGRELEDSITGDTSGYFQRMLVVLVQANRDPDSKVNDSLVEQDAQDLFKAGELKWGTDEEKFITILGTRSISHLRKVFDKYMTISGYQIEESIGRETSGHLEKLLLAVVKSVRSIPEYLAETLYHAMKGAGTDDCTLIRVMVSRSEVDLLDIREKFRKNWGKSLHAMIKGDTSGDYRNALLLICGGDDD >KAB0380453.1 hypothetical protein FD755_008237 [Muntiacus reevesi] LRGTVTDFPGFDGRADAGTLRKAMKGLGTDEGSILTLLTSRSNAQRPEIAVAF-----RGLLDDLKSELTGKCENLIVALMKPSRLYDAYELKHALKGAGANEKVLTEIIASRTPEGLRAIKQAYEEEYGPSLEDDVVGDPS-----------------------AQVEQNAQALFQAGELKWGTDEEKLITIFGTRR----------------FQIEETIDRETSGNLEHLLLAVVKSIRSIPAYLAETLYYAMKGAGTDERTLIRVVVSRSEIDLYNIRKEFRKNFATSLYSMIKGDTSGDYKKALLLLRGGEDD >XP_015797977.1 PREDICTED: annexin A5-like [Nothobranchius furzeri] FRGTVKASANFKASADAEVLHKAMKGLGTDEAAILQLLTARSNAQRQEIKASYKTLFGKDLVHDLKGELGGKFETLVVALMTPPLTYDVTSLHHAIKGAGTDEKVLVEILASRTPQQVKDIIAAYKTEYDHDLEKDICGDTSGHFQRLLVILLQASR--QTGIQEANIESDAQALFKAGEQKYGTDEQSFITILGNRSAEHLRKVFDAYTKLSGYEMEESIKRETSGSLRALLLAVVKCARSVPSYFAETLYYAMKGAGTDDDTLIRVMVTRCEVDMLDIRAAFRRMFACSLHSMIKGDTNGDYRKTLLLLCGGDDA >NP_001098345.1 annexin A10 [Oryzias latipes] SKGTVKAAANFKASADAEVLHKAMKGIGTDEDAILQLVCARSNAQRQEIKATYKTLFGKDLINDLKSELGGKFETLIVALMTPPTAYDVVSLRNAIKGAGTDEKVLVEILASRTPQQVKDIIAAYRKEYDADLEEDICGDTSGHFKRLLVILLQANR--QTGVQEGDIENDAQVLFKAGEQKFGTDEQTFVTLLGNRSAQHLRKVFDAYMKLSGYEIEESIKRETSGSLKDLLLAVVKCARSVPAYFAETLYNAMKGAGTDDDTLIRVMVTRGEVDMLDIRAEFRKLFARSLFSMIKGDTGGDYRKALLLLCGGDDA >XP_030286668.1 annexin A10 [Sparus aurata] SRGTVKASGNFNASADAEALYKSMKGLGTDEDTILQLLTARSNSQRQEIKATYKTLFGKDLVDDLKGELGGKFETLIVGLMTPPLAYDVTLLRNAIKGAGTDEKVLVEVLASRTCQQVKDIVGAYRQEYDDDLEEDVSGDTSGHFKRLLVILLQANR--QKGIQEGTVESDAQVLFQAGEKKFGTDEQTFVTILGNRSAEHLRKVFDAYMKLSGYEMEESIKRETSGPLRDLLLAVVKCARSVPAYFAETLYYAMKGAGTDDETLIRVMVSRSEVDMMDIRAEFRRMFPSSLFSMIKGDTGGDYRKALLLLCGGDDA >XP_026296548.1 annexin B9 [Apis mellifera] CTPTVYPAEPFDANADAALLRKAMKGFGTDEKTIIDVLTRRGIVQRLEVAEAYKTLYGKDLISDLKSELTGKLEDVIIALMTPLPHYYAKELHDAVSGLGTDEEAIVEILCTLSNYGIRTIAAFYENLYGKSLESDLKGDTSGHFKRLLVSLVQANRDENQGIDQTQAIADAQALYEAGEKQWGTDESQFNAILVTRSYQQLRQTFIEYEKISGHDIEVAIKKEFSGNLEKGLLGIVKCVKSKVGFFAERLYASMHGIGTKDRTLIRIIVSRSEIDLGDIKKAFEERYGKSLESWIAGDTSGDYKKALLSLVST--- >XP_030834955.1 annexin A5 isoform X1 [Strongylocentrotus purpuratus] THGTVRPHHPFDAEQDASVLRKAMKGMGTDEKAIINLLATRSNAQRQTIKLQFKTMYGKDLIHDLKSELSGKLEDLILAMFVPGPQYDAYAINKAIKGLGTDEEILIEILCTRTNKEIHEINEEYKKQFRTTMEKDCIGDTSGHFKRLLVSMCQGNRDESSTVDMAKAQAEANALYQAGEKKWGTDESEFNRILATRNFAQLRATFKEYTRIAQRDLLNSIEREFSGNIKNGLKTIVQCTQSRPSYFADRAYRAMKGAGTDDDTLIRVIVTRSEIDLVEIKKAFLEKYHKTLGKMVSGDTSGDYKKLLVALIGQD-- >XP_031556011.1 annexin-B12-like isoform X2 [Actinia tenebrosa] GRPSVTAYSPFDGKKDAEVLRKAMKGLGCDNKAITYLLCSRTNAQRQRISIEYKTIYGRDLMKDLKSELGGHFEDTVIALMTPPEEYDATLIRKALKGLGTNEEILIEILSTRTNNELVAIKNAYQRLFERDMEKDIAGDTSGHFKKFLISLAQAYREETDQVDIHKARASAEALYKAGEGRWGTDEAKFNSVLASKSFPQLRAVFDEYSKICKYDIEESIRREMSGDLKDGMVSIVQVVRNAPGFFAQKLYKSMKGLGTDDKALIRVVVTRSEIDILDIKDEFAKQYGQSLAQFIADDTKGNYKRILLQLIGESA- >XP_039270557.1 annexin A4-like isoform X2 [Styela clava] THGTVKAYPSFNAEEDAKILRKAMKGIGTDEKSIINVIGHRNNKQRQDIIIAYKQAYGKDLIKDLKSELSGNFESLVKAMFMKPRHYDVYCLERSMSGIGTDESALIEIFTSRSNAEIKEIKEIFKKERKKDLEKALKSETSGHFSRLLVSLCNASRNETTSVDQGKARADAQALYQAGEKKWGTDEATFNMIMCSRSIPQLRATFIEYHKIANRDISKSIEGEFSGDIEEGLKAVVETARSAPAYFAKRLYKSMSGAGTDDHTLIRIVVSRSEIDMVEIKQEFQRTYSKTLGSFIQGDTSGDYKNLLTTLVGP--- >CAE1230049.1 ANXA7_11 [Sepia pharaonis] EEGTLKPYPGFNAETDAQILRKAMKGFGTDEKAIIDVLGSRSNEQRQDIVRMFKTIFGKDLIKELKSELSGNFETVVLGLLYTPSMYDATELKKAMQGLGTNEDVLIEIMCSRSNKEIMEISDCFKKITGKSLENWLKSETSGHFCRLLVSLSTAGRSENQNVDLQSAEQDAKKLYEAGEKQWGTNESQFNAILASRSLPQLKAVFDAYKHLYNRDIEQVIASEMSGDLLSGMLSVVKVVKSKPCYFAERLYTSMKGAGTNDSTLIRVIISRCEIDMKQIKQEFQKMYGKTLDAMVKGDCSGDYCRILLRLLGNESY >XP_038060971.1 annexin A5-like [Patiria miniata] GTGTVKEKSNFDGHKEAEILRKAMKGIGTDEKAIIGVVTACSNAQRQRLLIDYKTMYGKDLVKNLKSELKSKLEEVVLDLMMTPALFDAHQLRKAMKGLGTDEAVLIEILCTRTNQEIVTIKEAYKKEFSRNLEKDVISETSGHFQRLLVSMTQGARREDPTVDQAKAKADAKALWDAGEKKWGTDESQFNVILASRSFPQLRATFEEYSKLGKYSIEQSIKREMSGDLEKGMLTIVDCVRNTPKYFSDKLYKSMKGLGTDDDTLIRIIVSRCEIDMVEIKQEFHRDHKQTLGKFIAGDTSGDYKKILLELVGGES- >NP_001262796.1 annexin B9, isoform E [Drosophila melanogaster] CTPTVYPADPFDPVEDAAILRKAMKGFGTDEKAIIEILARRGIVQRLEIAEAFKTSYGKDLISDLKSELGGKFEDVILALMTPLPQFYAQELHDAISGLGTDEEAIIEILCTLSNYGIKTIAQFYEQSFGKSLESDLKGDTSGHFKRLCVSLVQGNRDENQGVDEAAAIADAQALHDAGEGQWGTDESTFNSILITRSYQQLRQIFLEYENLSGNDIEKAIKREFSGSVEKGFLAIVKCCKSKIDYFSERLHDSMAGMGTKDKTLIRIIVSRSEIDLGDIKEAFQNKYGKSLESWIKGDTSGDYKRALLAIVGF--- >NP_001022756.1 Annexin [Caenorhabditis elegans] GTPSVFPVQGFNSNADAEVLRKAMKGLGCNNSKVISILCQRTNWQRQEISKAFKVMYGKDLIKELKGELHGDFEDLILALMDAPAIYDAKQLHRAMEGLGTKESVLIEIMTSRTNAQIQQVRDAYKMLFKKDLERDLIGETSGHFKRLLVSLCAGGRDESSQTDGLRANQDARRLLQAGEKRLGTDESTFNAILASQNFSQLRLVFEEYQKASNHSIEKAIEFEFSGDIRDGLLAVIAVIRNRPAYFAKLLHDSMKGLGTRDNDLIRLCVTRAEYDMGDIRNMFQSLYRTSLENMIKGDCSGAYKEGLIALVNGNRG
PhyML tree of selected proteins (XP_030834955_1_annexin_A5_isoform_X1__Strongylocentrotus_purpuratus_:0.34488235,XP_039270557_1_annexin_A4_like_isoform_X2__Styela_clava_:0.40430015,(((NP_001022756_1_Annexin__Caenorhabditis_elegans_:0.63902789,(XP_026296548_1_annexin_B9__Apis_mellifera_:0.1146382,NP_001262796_1_annexin_B9__isoform_E__Drosophila_melanogaster_:0.1737908):0.35539558):0.08040926,((tr_Q6P0V8_Q6P0V8_DANRE_Annexin_OS_Danio_rerio_OX_7955_GN_anxa5b_PE_1_SV_1:0.18573736,(XP_015797977_1_PREDICTED__annexin_A5_like__Nothobranchius_furzeri_:0.07078673,(NP_001098345_1_annexin_A10__Oryzias_latipes_:0.07582874,XP_030286668_1_annexin_A10__Sparus_aurata_:0.10329):0.03674229):0.11447502):0.15724716,((NP_001085335_1_annexin_A5_S_homeolog__Xenopus_laevis_:0.08862232,XP_040186261_1_annexin_A5__Rana_temporaria_:0.1920955):0.08629658,(((XP_003129266_2_annexin_A5__Sus_scrofa_:0.0097126,(((NP_001035567_3_annexin_A5__Bos_taurus_:0.0032756,(XP_017904654_1_PREDICTED__annexin_A5__Capra_hircus_:0.00000001,XP_012034784_2_annexin_A5_isoform_X2__Ovis_aries_:0.00325185):0.0032688):0.00650459,((XP_020763968_1_annexin_A5__Odocoileus_virginianus_texanus_:0.00000001,(KAB0380453_1_hypothetical_protein_FD755_008237__Muntiacus_reevesi_:0.07222287,(NP_037264_2_annexin_A5__Rattus_norvegicus_:0.02886275,NP_033803_1_annexin_A5__Mus_musculus_:0.01099529):0.03950652):0.00476016):0.00000001,(XP_043726893_1_annexin_A5_isoform_X1__Cervus_elaphus_:0.00000001,(XP_043294252_1_annexin_A5_isoform_X1__Cervus_canadensis_:0.00000001,KAF4019674_1_hypothetical_protein_G4228_011601__Cervus_hanglu_yarkandensis_:0.00000001):0.00324933):0.00324138):0.00328613):0.00322427,(NP_001301047_1_annexin_A5__Canis_lupus_familiaris_:0.01316747,XP_006930945_1_annexin_A5__Felis_catus_:0.00000001):0.00985575):0.00334356):0.00634954,((XP_003816466_1_annexin_A5__Pan_paniscus_:0.00000001,(XP_002815150_2_annexin_A5__Pongo_abelii_:0.00000001,(NP_001009099_1_annexin_A5__Pan_troglodytes_:0.00000001,(sp_P08758_ANXA5_HUMAN_Annexin_A5_OS_Homo_sapiens_OX_9606_GN_ANXA5_PE_1_SV_2:0.00000001,XP_004040389_1_annexin_A5__Gorilla_gorilla_gorilla_:0.00000001):0.00000001):0.00000001):0.00000001):0.0095553,XP_008266130_1_PREDICTED__annexin_A5__Oryctolagus_cuniculus_:0.06030887):0.00389353):0.12139598,((XP_013225254_2_annexin_A5_isoform_X1__Columba_livia_:0.01918341,(XP_010708237_1_annexin_A5__Meleagris_gallopavo_:0.00707969,NP_001026709_1_annexin_A5__Gallus_gallus_:0.00240235):0.02163913):0.08395226,(XP_006015678_1_annexin_A5__Alligator_sinensis_:0.00000001,XP_006263490_1_PREDICTED__annexin_A5_isoform_X1__Alligator_mississippiensis_:0.00643545):0.03860745):0.07702334):0.04255556):0.13642315):0.38966268):0.05041731,(CAE1230049_1_ANXA7_11__Sepia_pharaonis_:0.53098355,(XP_038060971_1_annexin_A5_like__Patiria_miniata_:0.29459475,XP_031556011_1_annexin_B12_like_isoform_X2__Actinia_tenebrosa_:0.51287796):0.11165263):0.04584456):0.09113181);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)