PB0199
DATABASE


Click here to access PB0199 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0199 Q9UK55 Protein Z-dependent protease inhibitor SERPINA10 PZI, ZPI, serpin family A member 10 Homo_sapiens Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Also inhibits factor XIa in the absence of cofactors.

DomainsGene Ontology
PF00079 (Serpin)
GO:0004867 (enables) serine-type endopeptidase inhibitor activity
GO:0005515 (enables) protein binding
GO:0008201 (enables) heparin binding
GO:0030414 (enables) peptidase inhibitor activity
GO:0007596 (involved in) blood coagulation
GO:0007599 (involved in) hemostasis
GO:0010466 (involved in) negative regulation of peptidase activity
GO:0010951 (involved in) negative regulation of endopeptidase activity
GO:0097421 (involved in) liver regeneration
GO:0005615 (is active in) extracellular space
GO:0005576 (located in) extracellular region
GO:0005788 (located in) endoplasmic reticulum lumen
GO:0070062 (located in) extracellular exosome

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences


Created by Puigbo and Nakamura @ University of Turku (2022)