PB0199

DATABASE

Click here to access PB0199 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0199	Q9UK55	Protein Z-dependent protease inhibitor	SERPINA10	PZI, ZPI, serpin family A member 10	Homo_sapiens	Inhibits activity of the coagulation protease factor Xa in the presence of PROZ, calcium and phospholipids. Also inhibits factor XIa in the absence of cofactors.

Domains

Gene Ontology

PF00079 (Serpin)

GO:0004867 (enables) serine-type endopeptidase inhibitor activity GO:0005515 (enables) protein binding GO:0008201 (enables) heparin binding GO:0030414 (enables) peptidase inhibitor activity GO:0007596 (involved in) blood coagulation GO:0007599 (involved in) hemostasis GO:0010466 (involved in) negative regulation of peptidase activity GO:0010951 (involved in) negative regulation of endopeptidase activity GO:0097421 (involved in) liver regeneration GO:0005615 (is active in) extracellular space GO:0005576 (located in) extracellular region GO:0005788 (located in) endoplasmic reticulum lumen GO:0070062 (located in) extracellular exosome

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|Q9UK55|ZPI_HUMAN Protein Z-dependent protease inhibitor OS=Homo sapiens OX=9606 GN=SERPINA10 PE=1 SV=1 MKVVPSLLLSVLLAQVWLVPGLAPSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKA SEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPT ETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFN LSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKG KWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLV VLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRI FSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPF HFMIYEETSGMLLFLGRVVNPTLL >tr|Q5RIH8|Q5RIH8_DANRE Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10a OS=Danio rerio OX=7955 GN=serpina10a PE=3 SV=1 MKMGFFTLLIEASLLSVSVLGQTTDVEELAIKNADFATRLYSKIASSSDDNVAVSTLGAT LALATLAAGAGGATQSELLQGIGVDSMVKDGEQERIQNILQQLREDAAQIPATGLFIKQD VKADDSFSNQVKQYYNADVQNVNYANGQQAKGSINDYVRGRTGEKVRDVVENVDPQSMAI LISAAFFTGQWLQPFNATFTQEDRFYVNKYNIVQVPMMLRSGKYYLAYDPTFKVGILKLP CENGIAMLVLLPDEDVDYTYVDESMTGEVFRGWVAKLKKTKLEIQLPRFSLKQSNSLSVS LPSLGVKEIFGSTANLTGISSSEGLKLSEVVQKVAVDVDESGGSLAEASGNLFMNPLPPR LTFNRPFIFVVYHEVTKCILYIGRVVDPTKN
Selected proteins from model organisms >sp|Q9UK55|ZPI_HUMAN Protein Z-dependent protease inhibitor OS=Homo sapiens OX=9606 GN=SERPINA10 PE=1 SV=1 MKVVPSLLLSVLLAQVWLVPGLAPSPQSPETPAPQNQTSRVVQAPKEEEEDEQEASEEKA SEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDGNMVFSPFGMSLAMTGLMLGATGPT ETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFN LSKRYFDTECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKG KWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLV VLMEKMGDHLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRI FSPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPF HFMIYEETSGMLLFLGRVVNPTLL >tr|Q5RIH8|Q5RIH8_DANRE Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10a OS=Danio rerio OX=7955 GN=serpina10a PE=3 SV=1 MKMGFFTLLIEASLLSVSVLGQTTDVEELAIKNADFATRLYSKIASSSDDNVAVSTLGAT LALATLAAGAGGATQSELLQGIGVDSMVKDGEQERIQNILQQLREDAAQIPATGLFIKQD VKADDSFSNQVKQYYNADVQNVNYANGQQAKGSINDYVRGRTGEKVRDVVENVDPQSMAI LISAAFFTGQWLQPFNATFTQEDRFYVNKYNIVQVPMMLRSGKYYLAYDPTFKVGILKLP CENGIAMLVLLPDEDVDYTYVDESMTGEVFRGWVAKLKKTKLEIQLPRFSLKQSNSLSVS LPSLGVKEIFGSTANLTGISSSEGLKLSEVVQKVAVDVDESGGSLAEASGNLFMNPLPPR LTFNRPFIFVVYHEVTKCILYIGRVVDPTKN >NP_598301.2 protein Z-dependent protease inhibitor precursor [Rattus norvegicus] MRVVSSLFLPVLLAEVWLVSSFNLSSHSPEAPIRLVSQDYENQTWEEYEWADPRDDNEYWLRASQQLSNE TSSFGFSLLRKISMRHDGNVIFSPFGLSVAMVNLMLGAKGETKVQVENGLNLQALSQAGPLILPALFKRV KETFSSNKKLGLTQGSFAFIHKDFEIKKTYFNLSTMYFDTEYVPTNFRNSSQARGLMNHYINKETEGKIP KLFDEINPETKLILVDYILFKGKWLTPFDPIFTEADTFHLDKYKAVKVPMMYREGNFASTFDKKFRCHIL KLPYQGNATMLVVLMEKSGDHLALEDYLTTDLVEMWLQDMKTRKMEVFFPKFKLNQRYEMHELLKQVGIR RIFSTSADLSELSAVARNLQVSKVVQQSVLEVDERGTEVVSGTVSEITAYCMPPVIKVDRPFHFIIYEEM SQMLLFLGRVVNPTVL >NP_659083.2 protein Z-dependent protease inhibitor isoform 1 precursor [Mus musculus] MRVASSLFLPVLLTEVWLVTSFNLSSHSPEASVHLESQDYENQTWEEYTRTDPREEEEEEEEKEEGKDEE YWLRASQQLSNETSSFGFNLLRKISMRHDGNVIFSPFGLSVAMVNLMLGTKGETKVQIENGLNLQALSQA GPLILPALFKKVKETFSSNRDLGLSQGSFAFIHKDFDIKETYFNLSKKYFDIEYVSINFQNSSQARGLIN HCIVKETEGKIPKLFDEINPETKLILVDYVLFKGKWLTPFDPSFTEADTFHLDKYRAIKVPMMYREGNFT STFDKKFRCHILKLPYQGNATMLVVLMEKTGDYLALEDYLTVDLVETWLQNMKTRKMEVFFPKFKLNQRY EMHELLKQMGIRRLFSTSADLSELSAMARNLQVSRVLQQSVLEVDERGTEAVSGTLSEIIAYSMPPAIKV NRPFHFIIYEEMSRMLLFLGRVVNPTVL >XP_015143253.1 protein Z-dependent protease inhibitor [Gallus gallus] MKIRIYLLLLCELCFEISKADIKPKSPKKDKRLNFLGRNKNVSISEEWHQHKNDHKPLEEQSFEELTLHN FTEKTANFGFNLYRKIAMKLDNNIIISPLSVTTLMATYLLAAEGETHRQIAKALNLHSLKDRDRHYLPAL FKQLKDNITTNEELLFVQGILSFIQKDFTVREAFLNLSKQYFDMEFLCVDFQNSTQAKFVINQNIKQRTK GKISELFEEVDRHSKLLLLDYIFFKGKWLYPFNSEFTEIETFHINKYRSVQVPMMFKSDKVNSTYDENLR CNVIKLPYKGKAYMLIVIPEKGEDYVSLEDHLTMELVESWLANMKSRNMDISFPKFKLEQKYKMKKLLYA LGIKNLFARTADLSHLTDQKHLTVSQVVQKAVIEVDEKGTEAAAATGSEIIAFSVPPVLKVDRPFLFMIF EETFKTLLFIGRVVDPTET >XP_024204665.1 protein Z-dependent protease inhibitor isoform X1 [Pan troglodytes] MSRSAQELLGYHCRLQDKLQEQEGSLAAEGRHSLASAADHMKVVPSLLLSVLLAQVWLVPGLAPSPQSPE TPAPQNQTSRVVQAPREEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDGNMVF SPFGMSLAMTGLMLGASGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSHNLELGLTQGSFAFIHK DFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETGGKIPKLFDEIDPETKLILVDYILFKG KWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHL ALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVS RVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPTLL >NP_001092467.1 protein Z-dependent protease inhibitor precursor [Bos taurus] MWAVLSLPLACLLAQAWLVPGSTLASHSPEAQAGLETLLTPMAQNKTSQTSERQWAPEEEEEREEDSPWL LAEGQQLSREASNLGFSLLRKISLKHDGNVVFSPLGLAWAMAALTLGARGHSRAQLEDLLLQAWNQTWPV VNQTRPPRLPALFKQLQESLSHNPELGLAQGSFAFIHKDFDIRETFLNLSKRYFDMECVTVDFHNTSQAK RLINHYMNQETQGKLPKLFDEINPDTKLILVDYILFKGKWLIPFDPALTEMDTFYLDKYKEVKVPMMYRS GKFASTFDKKFHCHVLKLPYRGNASMLVVLVERIGDHLTLEDYLTTDLVDTWLRNMKTRKMEVFFPKFKL DQKYKMHELLKQMGVQKIFLPWADLSDLMVTERNLKVSKVLQRATIEVDEEGTEAMAGTLLEITAYYMPP IVKVDRPFLFIIYEETSRTVLFLGRVVDPTLL >NP_001125107.1 protein Z-dependent protease inhibitor precursor [Pongo abelii] MKVVPSLLLSVLLAQVWLVPGLAPSPQSPETPAPQNQTSRVVQAPREEEEDEQEASEEKAGDEEKAWLTA SRQQLAKETSNFGFSLLRKISMRHDGNIVFSPFGTSLAMTGLMLGATGLTETQIKRGLHLQALNPTKPGL LPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFLNLSKRYFDTECVPMNFRNASQAKRLMNHYIN KETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVDTFHQDKYKTIKVPMMYGAGKFASTFD KNFCCHVLKLPYQGNVTMLVVLMEKMGDQLALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHE LLRQMGIRRISPFADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAAILSEIIAYSMPPAIKVDRPFH FMIYEETSGMLLFLGRVVNPTLL >XP_010710160.1 protein Z-dependent protease inhibitor [Meleagris gallopavo] MKIGIYLLLLCEICFEISKADIKPKSPKKDKRLNFLGKNKNNSISEEWHQHKNYSEPLEDESFEELTLHN FTEKTANFGFNLYRKIAMKLDNNIIISPLSVSTLMATYLLAAEGETHRQIAKALNLHPLEDRDRHYLPTL FKQLKDNITTNEELLFVQGILSFIQKDFVVREAFLNLSKQYFDMEFLRVNFQNITQAKSVINQNIKQRTK GKISELFEEVDRHSKLLLLDYIFFKGKWLYPFNSEFTEIETFHINKYRSVQVPMMFKSDKVNSTYDENLR CNVIKLPYKGKAYMLIVIPEKGEDYVSLEDHLTMELVESWLANMKSRNTDISFPKFKLEQKYKMKKWLYA LGIKNLFARTADLSHLTDQKYVTVSQVVQKAVIEVDEKGTEAAAATGSEIIAFSAPPVIKVDRPFLFMIF EETFKTLLFIGRVVDPTEM >XP_027813160.1 protein Z-dependent protease inhibitor isoform X1 [Ovis aries] MRVVLSLPLACLLAQAWLAPGSTLASHSPEAQEGLETLLTPRAQNKTSQTSERPWAPDEEKGEEDSPWLS AKGQQFSREASNLGFSLLRKISLKHDGNVVFSPLGLAWAMAALTLGARGHSRAQLEGLLLQAWNQTRPAV NQTRTPRLPALFKRLRESLSHNPELGLAQGSFAFIHKDFDIRETFLNLSKRYFDMECVTVNFRNTSQAKR LMNHYVNQETQGKLPKLFDEINPDTRLILVDYILFKGKWLIPFDPALTEMDTFYLDKYKVVKVPMMYRSG KFASTFDKNFGCHVLKLPYRGNASMLVVLMGRIGDHLTLEDYLTTDLVDTWLRNMKTRKMEVFFPKFKLD QKYKMHELLKQMGVQRIFLPWADLRDLTVTERNLKVSKVLQRAMIEVDEEGTEAMAGTLLEITAYYMPPI IRVDRPFLFIIYEETSRTVLFLGRVVNPTLL >XP_004055674.1 protein Z-dependent protease inhibitor isoform X1 [Gorilla gorilla gorilla] MSRSAQELLGYHCRLQDKLQKQEGSLAAEGRHSLASTADHMKVVPSLLLSVLLAQVWLVPGLAPSPQSPE TPAPQNQTSRVVQAPREEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDGNMVF SPFGMSLAMTGLMLGATGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRDSLSHNLELGLTQGSFAFIHK DFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETGGKIPKLFDEIDPETKLILVDYILFKG KWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFHCHVLKLPYQGNATMLVVLVEKMGDHL ALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVS RVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPTLL >XP_005506179.1 protein Z-dependent protease inhibitor isoform X1 [Columba livia] MLHFCYERRTTKKQKNSLLDVNMKTGIYLLVLSEICVEISKASIKLKTPQKEKENKFWEINNNVNIAEDW HNHKNMSKPFEKQGLEDFTLYNFTEKTANFGFNLYRKIAMTHDNNVIISPLSVSTLMTAYMLAAKGETHR QIAKGLNLHALKDTVDRHHLPALFKQLKDNITMNDELLVQGTLSFIQKDFRLKESFLNLSKQYFDMEFLR VDFQNFTQAKLVINQNIKKRTKGKIPELFEELDRHTKLLLVDYIVFKGKWVYPFNSKFTEMETFHINKYR SVQVPMMFKSDKVNSTFDENLRCTVIKLPYKGKAHMLIVIPEKEGDYISLEDHLTTEVVEFWLGNMKTRK VDISFPKFKLEQKYKLKKLLHALGIKNLFTRMADLGHLTDQGYVAVSQVVQKAVIEVDEEGTEATAASGS EITAFTVPPVIKVDRPFLFMIFEETFKTLLFIGRVVDPTEM >XP_005695405.1 PREDICTED: protein Z-dependent protease inhibitor [Capra hircus] MRVVLSLPLACLLAQAWLAPGSTLASHSPEAQEGLETLLTPRAQNKTSQTSERPWAPEEEEGEEDSPWLS AKGQQFSREASNLGFSLLRKISLKHDGNVVFSPLGLAWAMAALTLGARGHSRAQLEGLFLQAWNQTWPAV NQTRTPHLPALFKRLRESLSHNPELGLAQGSFAFIHKDFDIRETFLNLSKRYFDMECVTVNFRNTSQAKR LMNHYVNQETQGKLPKLFDEINPDTRLILVDYILFKGKWLIPFDPALTEMDTFYLDKYKVVKVPMMYRSG KFASTFDKNFGCRVLKLPYRGNASMLVVLMGRIGDHLTLEDYLTTDLVDTWLRNMKTRKMEVFFPKFKLD QKYKMHELLKQMGVQRIFLPWADLRDLTVTERNLKVSKVLQRAMIEVDEEGTEATAGTLLEITAYYMPPI IRVDRPFLFIIYEETSRTVLFLGRVVNPTLL >XP_006025546.1 protein Z-dependent protease inhibitor [Alligator sinensis] MKTGICLLLLWEMCLGMNTSSVKTRMPEKNKEHFLSKKQTFSISEEHFHHKNIPKPFEVQVPLESTVYNV TEKSTNFGFNLYRKIAMQHDNNVLFSPLSLSFLMAAFMLGTKGETNNQIVQGLNLHLLKDKENPYHLPAL FKQLKENITANEEFILQQGSFAFIQKDFCLNESFLNLSKEYFDMEFRSVDFNNSTQAKEVINQNVNKMTK GKIQELFEDFDTHAKLVLVDYVFFKGKWIHPFNARLTEPEFFHIDKYRSVQVPMMFKSDKVASTFDENLR CTVVKLPYKGRVHLLIAVPEKEGDYVSLEDHLTAELVELWLRNMKTRKIDFFLPKFKLDQNYQMHKLLQT LGIKNLFTNQADLSQLTDQMYARVSQVIQRAVIEVDERGTEAAAASGSEMTAYSVPPTIRVNRPFLFMVF EETFKTLIFMGRVVNPTEL >XP_006266325.1 PREDICTED: protein Z-dependent protease inhibitor [Alligator mississippiensis] MKTGICLLLLWEMCLGMNTSSVKTRMPEKNKEHFLSKKQTFSISEEHFHHKNIPKPFEVQVPLESTVYNV TEKSTNFGFNLYRKIAMQHDNNVLFSPLSLSFLMAAFMLGTKGETNNQIVQGLNLHLLKDEENPYHLPAL FKQLKENITANEEFILQQGSFAFIQKDFCLNESFLNLSKEYFDMEFRSVDFNNSTQAKEVINQNVNKMTK GKIQELFEDFDTRAKLVLVDYVFFKGKWLHPFNARLTEPEFFHIDKYRSVQVPMMFKSDKVASTFDENLR CTVVKLPYKGRVHLLIAVPEKEGDYVSLEDHLTAELVELWLRNMKTRKIDFFLPKFKLDQNYQMHKLLQT LGIKNLFTNQADLSQLTDQMYARVSQVIQRAVIEVDERGTEAAAASGSEMTAYSVPPTIRVNRPFLFMLF EETFKTLIFMGRVVNPTEL >XP_008956493.1 protein Z-dependent protease inhibitor isoform X1 [Pan paniscus] MSRSAQELLGYHCRLQDKLQKQEGSLAAEGRHSLASAADHMKVVPSLLLSVLLAQVWLVPGLAPSPQSPE TPAPQNQTSRVVQAPREEEEDEQEASEEKASEEEKAWLMASRQQLAKETSNFGFSLLRKISMRHDGNMVF SPFGMSLAMTGLMLGASGPTETQIKRGLHLQALKPTKPGLLPSLFKGLRETLSHNLELGLTQGSFAFIHK DFDVKETFFNLSKRYFDTECVPMNFRNASQAKRLMNHYINKETGGKIPKLFDEIDPETKLILVDYILFKG KWLTPFDPVFTEVDTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEKMGDHL ALEDYLTTDLVETWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSPFADLSELSATGRNLQVS RVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPTLL >XP_020754828.1 protein Z-dependent protease inhibitor [Odocoileus virginianus texanus] MRVVLSLPLACLLAQAWLAPGSTLASRSLEVQAGLETLLTARAQNKTNQTRERLWAPEEEEGEEDSPWLS TEGQKLSWEASNLGFSLLRKISLKHDGNVVFSPLGLAWAMAALTLGAGGHSRAQLEELLSQTLNQTRPPR LPALFKRLRESLSHNPELGLAQGSFAFIHNDFDIRETFLNLSKRYFDTECVTVNFRNTSQAKRLMNHYMN QQTQGKLPKLFDEINPDTELILVDYILFKGKWLIPFDPALTEMDTFYLDKYKTVKVPMMYRSGKFASTFD KNFRCHVLKLPYRGNASMLVVLMGRIGDHLTLEDYLTTDLVDTWLRNMKARKMEVFFPKFKLDQKYKMHE LLKQMGVRKIFSPWADLSNLAVTERNLKVSKVLQRAMIEVDEEGTEAMAGTLSEITAYYMPPIIRVDRPF LFIVYEETSRTVLFLGRVVNPTLL >XP_040188191.1 protein Z-dependent protease inhibitor [Rana temporaria] MRWTFVFILLFGLTSAHQPTKGKPKKEKHHQEKMPLLEESTLNLLNGTREISALDLSNMNNNFGFNLYRR TADKHDDNIFFSPLSVSFLLGALTLGSRGMTHEQLLSGLGWEPFKKNPDVLHTLLKDLKDGVMKSDGYSL DVADLALLHESFDLNPEFLNQTMTYFHMEFQSVDFHDRHVLETIRDLIRLKTRGRISELQDEIDPQTKMM LLNFIFFKGKWQTPFKSDSTQADTFYVNKYSSVKVPMMCKTEKVAAMFDKSLSCTVLKLPYRGGAHMLVV MPQNDGNFDALEDGLSSELVASWLRKMKFRETEIFFPKFQLDHKYKMKSSLDELGIKDIFTGRANLTGVT EERNLMLSEVTQRAVIDIDEIGTEATAVTGAEMVPYFLPYTIRINQPFIFMIFDEKFKSLLFIGRVTDPT KH >KAF4018099.1 hypothetical protein G4228_009825 [Cervus hanglu yarkandensis] MWAVLSLPLACLLAQAWLAPGSTLASRSPEVQAGLETLLTARAQNKTNQTSERLWAPEEEEGEEDSPWLSTEGQKLSREA SNLGFSLLRKISLKHDGNVVFSPLGLAWAMAALTLGAGGHSRAQLEELLLQTLNQTRPPRLPALFKRLRESLSHNPELGL AQGSFAFIHKDFDIRETFLNLSKRYFDMECVTVNFRNTSQAKSLMNHYMNQQTQGKLPKLFDEINPDTELILVDYILFKG KWLIPFDPALTEMDTFYLDKYKTVKVPMMYKSGKFASTFDKNFRCHVLKLPYRGNASMLVVLMGRIGDHLALEDYLTTDL VDVWLRNMKARKMEVFFPKFKLDQKYKMHELLKQMGVRKIFSPWADLSNLAATERNLKVSKVLQRAMIEVDEEGTEAMAG TLSEITAYYMPPIIRVDRPFLFIVYEETSRTVLFLGRVVNPTLL >KAB0352921.1 hypothetical protein FD754_017778 [Muntiacus muntjak] MWAVLSLPLACLLAQAWLAPGSTLASRSPEVQAGLETLLTARAQSKTSQTSERRRAPEEEEGEEDSPWLSPEGQKLSGEA SNLGFSLLRKISLKHDGNVVFSPLGLAWAMAALTLGARGHSRAQLEEPLLQTLNQTRPPRLPALFKRLRDSLSHNPELGL AQGSFAFIHKDFDIRETFLNLSKTYFDTECVTVNFRNTSQAKRLMNHYMNQQTQGKLPKLFDEINPDTELILVDYILFKG KWLIPFDPALTEMDTFYLDKYKTVKVPMMYRSGKFASTFDTNFRCHVLKLPYRGNASMLVVLMGIGDHLTLEDYLTTDLV DAWLRNMKARKMEVFFPKFKLDQKYKMHELLKQMGVQKIFSPWSDLSNLAVTERNLKVSKILQRAMIEVDEEGTEAMAGT LSEITAYYMPPVIKVDRPFLFIVYEETSRTVLFLGRVVNPTLL >XP_043346178.1 protein Z-dependent protease inhibitor [Cervus canadensis] MWAVLSLLLACLLAQAWLAPGSTLASRSPEVQAGLQTLLTARAQNKTNQTSERLWAPEEEEGEEDSPWLSTEGQKLSREA SNLGFSLLRKISLKHDGNVVFSPLGLAWAMAALTLGAGGHSRAQLEELLLQTLNQTRPPRLPALFKQLRESLSHNPELGL AQGSFAFIHKDFDIRETFLNLSKRYFDMECVTVNFRNTSQAKSLMNHYMNQQTQGKLPKLFDEINPDTELILVDYILFKG KWLIPFDPALTEMDTFYLDKYKTVKVPMMYKSGKFASTFDKNFRCHVLKLPYRGNASMLVVLMGRIGDHLTLEDYLTTDL VDVWLRNMKARKMEVFFPKFKLDQKYKMHELLKQMGVRKIFSPWADLSNLAATERNLKVSKVLQRAMIEVDEEGTEAMAG TLSEITAYYMPPIIRVDRPFLFIVYEETSRTVLFLGRVVNPTLL >XP_043778021.1 protein Z-dependent protease inhibitor [Cervus elaphus] MWAVLSLLLACLLAQAWLAPGSTLASRSPEVQAGLETLLTARAQNKTNQTSERLWAPEEEEGEEDSPWLSTEGQKLSREA SNLGFSLLRKISLKHDGNVVFSPLGLAWAMAALTLGAGGHSRAQLEELLLQTLNQTLPPRLPALFKQLRESLSHNPELGL AQGSFAFIHKDFDIRETFLNLSKRYFDMECVTVNFRNTSQAKSLMNHYMNQQTQGKLPKLFDEINPDTELILVDYILFKG KWLIPFDPALTEMDTFYLDKYKTVKVPMMYKSGKFASTFDKNFRCHVLKLPYRGNASMLVVLMGRIGDHLTLEDYLTTDL VDVWLRNMKARKMEVFFPKFKLDQKYKMHELLKQMGVRKIFSPWADLSNLAATERNLKVSKVLQRAMIEVDEEGTEAMAG TLSEITAYYMPPIIRVDRPFLFIVYEETSRTVLFLGRVVNPTLL >KAB0369185.1 hypothetical protein FD755_019190 [Muntiacus reevesi] MWAVLSLPLACLLAQAWLAPGSTLASRSPEVQAGLETLLTARAQNKTNQTSERLWAPEEEEGEEDSPWLSPEGQKLSGEA SNLGFSLLRKISLKHDGNVVFSPLGLAWAMAALTLGARGHSRAQLEELLLQTLNQTRPPRLPALFKRLRESLSHNPELGL AQGSFAFIHKDFDIRETFLNLSKRYFDTECVTVNFRNTSQAKRLMNHYMNQQTQGKLPKLFDEINPDTELILVDYILFKG KWLIPFDPALTEMDTFYLDKYKTVKVPMMYRSGKFASTFDTNFRCHVLKLPYRGNASMLVVLMGIGDHLTLEDYLTTDLV DTWLRNMKARKMEVFFPKFKLDQRYKMHELLKQMGVRKIFSPWSDLSNLAVTERNLKVSKILQRAMIEVDEEGTEAMAGT LSEITAYYMPPVIKVDRPFLFIVYEETSRTVLFLGRVVNPTLL >OCT68273.1 hypothetical protein XELAEV_18039571mg [Xenopus laevis] MKHRLCLLLPFLLTGLCFADHAIKQHKPSRKQRLDESEWNKQISAATVMDSMNTSTNDQQIPPVLSVSNVSQMISDFGFN LYRKIANKHDDNIFFSPFSVSLGLSSLLLGTRGNTYDQLLHGLNYNRFKEQENPYLLPELLKTIKEKIAQNEELVLNIGS LSFLHETFSMKEEFINLTKTYFDMEYEFIDFHSSKAKNEINAHVEKLTKGLISNFYDFLDPQTKLLLLDYIFFKGKWQYP FNPALTEEDTFFIDKYNSVTVPMMYKSDKVASLLDKDLSCTVFKLPYRGNAHMLIIKPEKEGDFGILEDHLTKELIDSWL AKMQSRKTDIFFPKFKLDQKYKLKSSLNELGIKELFTGRANLTDLTEERNLLLTEVTQQAIIDVNERGTEAAAAAGAEII AYSLPLTIRVNRPFLFLIYEEAFQSLLFIGRVTNPTKL >XP_004082346.1 protein Z-dependent protease inhibitor isoform X1 [Oryzias latipes] MVFNGIKMLVVFALTCMCFIVPVHQSLLPNATILDLSYKNMDFAMNLYRKIANYHDKNIFFSPLSVSTSFAALLMASDGI THQEILKVCNLEQFEMVDQPQLIPRLFQDLQENISRNGSLQLEQSMALFIRQRFEVEKTFQDNLKNFFQADINVLNFGNT KDSIKTINDYVRQKTADKVPEMISTLNAMTKLLLINTIFFQGVWQIPFNPNFTENAPFHIDNYNIVQVPMMFVEDKFYTM EDEPLGARVLKLPYKEGVSMLILLPNKKTDYTTIDNEITAQRFLSWIRNLEPMKLEVNMPKFKMERAYSLHNILPEMGMS SLFTDFANLTRLSKAQALRVSEVLHKAVIEVDEVGTTAAAATATGIIPYALPRRFTINRPFFFFIYHEETNALLFMGRVI NPTKN >XP_015825579.1 PREDICTED: protein Z-dependent protease inhibitor-like [Nothobranchius furzeri] MVPKIKMAFLVVLACLCFFTPTHQSPPPNAAILELSYENTDFAMNLYRKLANYNDKNIFFSPLSVSTTFASLLMASGGIT REEILRGLDLNQLETNQTEHIPKLFQLLQENIAQNGSLKLEQSMALFISQQFEVKKTFEDRLKTFFQADIRTVDFAESTK SITLINEYIKQKTGGKIVKMISTLDETTRLLLINSIYFQGAWKNPFNPNLTESAAFHIDNYNVVQVSMMMKEARFFVTED VLLGARVLKLPYQDGVSMLILLPNKNVDYTSIDEEISAEKFSSWIEGLRKTKLEVHVPKFKMEQAYALQNILPDMGMTSL FSTSANLTGIGEGQDLMVSEVLHKAVIEVDETGTTAAAATTVGITPYSLPRMFIVDRPFFFFIYHEETKSLLFMGRVIDP TKN >XP_030247366.1 protein Z-dependent protease inhibitor-like isoform X2 [Sparus aurata] MFEPPYLSQTPNMVVHKMKMGFIPIVTFMCFLAPLQQAHAPSATIADLSFKNMDFAMELYRKISSFHDKNIFFSPLSIST SFAALLMASDGVTRDEMLRGLNLEQLEQADQPELIPKLFQLLNENITQNGSLKLDQGMALFMAPQFEVQNMFEDQIKEFF SADIKSVNFGDTKGAIRFINEYVKHRTHDKVTEMISSLDSATKLMLINTIFFQGAWQMPFNPNFTESAPFYIDNYSVVQV PMMFMEDKFYMMEDISLGAKGLKLPYQEGVSMLILLPKKGVDYTVIDEEITAEKFLSCIKKLQKIKLEVHIPKFKMEQSY SLHNLLPEMGMASVFSNSANLTKLSKSGRLKVSEVLHKAVIEVDETGTTAAAATTIGITPFSLPRTFTVNKPFFFFIYHE DTNCVLFMGRVIDPTKN >XP_038050239.1 leukocyte elastase inhibitor-like [Patiria miniata] MYKLTLLVTSSRPDSIMAVIQIISILTVIALLYMSVFATSTGPDPQLELADANNRFAFHLYQTLADDPHRDNIFFSPMSI SIALAMTSLGARGNTARQIKDVLKFSTLEESRLHSSFAELNSAIFGANADKYVLRKANRLFGHKGFDLRQEFLADAERYY SSHMASLDFVEDTEVAREFINSWVGRETEDKIRDLLPHGSITGMTQLVLVNAIYFKADWVRQFDKSKTFDQDFHVSKDQV LEVPMMHRKSKFNFAEDITLRCKLIELPYVGQDFSMIVVLPDEIDGIDRLQKHLTNEKLQHLLNNLSNVTVGVAIPKFKL EETLHMNDVLYSMGMRDLFVRDKADLSGITGTRDLFVSSVIHRAFLEVNEEGSEAAAATAVTINKRSISLAPEFIADHPF LFFIADSKTKAIVFMGHCRKPEGVSLNHEEL >XP_031557330.1 leukocyte elastase inhibitor-like [Actinia tenebrosa] MGNNIITCNTFRLHSVLILAVSLVFCSVLLSTMAQADLIKASTNKFSLHLHQVLRGQATFDAEQNLFYSPSSILVALAMT HLGARGNTAKQMSSSFHLDEIPEKQLNAEFQKFLQKLNQSNAKGNEIAMANRLFVQMGFEVSKQFQEDSEKFFNAEAALV DYQKNSEGARQEVNQWVEQKTKNKIKDLIPEGMFGPDTRLTLVNAIYFKGSWMSKFDSNNTQTGPFQLTPSKTVQVPMMY KSDKFKYFENEGLKCKMLELPYSDEKISMIILLPDEVDGLSKLEDSLNYSKLDEAIGHLKMAPKEEVEVTLPKFKLSEKF SLKEVLSKMGASDLFNAAKADLTGINKDGQLYVSEVVHKAFVDVNEEGTEAAAATAVRVALMCMPMNPIFFANHPFLFLI RHNESGAILFIGRLANPK >XP_039269246.1 serpin B9-like [Styela clava] MIKMKNIIISLGIAICLAVMSKADKMKTSTTPSDECSMASGAEANRIFAYEMYKVAAKLKPNQNIFLAPTTVGSGLSMML PGARESTKDQMLEGLMFKNTSTGFEPNDIECLMKMYSNELIETKLEDRGKGTKDVKAAKEDTLQLRTANRLFGEKSFNFS SKFIEQTAKYGVEMTKMNFQTDSAESRNFINQWVEKATEGKIKDLFSGKAIRPDTVLAVVSAIYFKGLWKYPFDPLNTFK QDFKVNDNKTVKADFMTKMINYRMTYSEDLEAQILDVPYDGDAYGKYNASMILIVPTRRGSIERVEEMLSEKTMKPILDE LQAEQQYTQRVRLLLPKFKMSKTYQLKPILRRLGIKNLFNPIRANLSGMIDPSEISPNLYVSTAVHKTFIKVDEKGTEAA GASGFGIVPLSLPPRLFCNRPFLFMIYEKNTDGVLFIGKVNDPTVQ >XP_030838146.1 leukocyte elastase inhibitor A isoform X3 [Strongylocentrotus purpuratus] MAFHITMVTLLTLGMMGSEVKAVEVGEHTQQLARANNAFALHLYSATRATHPDQNLFFSPLSVSTALGMTHLGARGTSSA QMSEVLRFNLLEEEHLHASFKQLNALLYESSNKYTLKSANKLFGKAGADFLQEFLDNTGNFYNSAFEAVKDFAAPEARTM INDWVAKETEDKIQNLFPDGVLNSLTQLVLVNAIYFKSNWVKSFNRDDTEPGVFRMKDETAHLPMMFKDGEVMMTDDKER KCFVLEMPYDGEDLSMLAILPWDDDGLANVEEQLSMEVLDFWDSDLEPENAMYWVPRFKLEDTFSLSSILQSMGMADAFD ATKADFSGMTGDQSLHISEVIHKAFVEVNEEGTEAAAATGVTMTKRSISKRYRLRFDHPFLFLIRDRRTKAVLFLGRLVD PPHDIRVHHEEL >NP_524953.1 serpin 55B [Drosophila melanogaster] MFDFNLEFARGGARFTSELFQLLSAGGLKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHFVSNFPPEVAQTFQFVL EKYRNSNLLRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFALNDAAAQAINAWVNAKTQGKITELVSADSFSDNTR LVLLNALHFKGSWAHKFSEERTEEDIFWVGEEEQVKINYMNQKAKFNYGFFEDLGCTALEMPYQDSDLSMFVLLPQERTG IYALAEKLKTVNLVDLADKLTVEEVHVKFPKFKVDYSLELAEKLKQLGITKMFTDQAEFSNLLESPEGVFVSKVLHKATI EVNEEGTEAAAATGMIMMTRMMTFPLQFQADRPFLYVIWNKKNILFAGAFVKAA >XP_016773435.2 serine protease inhibitor 27A isoform X2 [Apis mellifera] MCYLIVTYIIILTLKQCKSEIMNNKSQSIFDTNVTRNINHEIINHNKTNNDFVPYQGERFDIFDWTFFKSISKKYSKNVI ISPISLKIALVLLYEGAQGETAYELANILQLPATRNATRKKFSNILQSLQTNFTAYTLNIGTRIYIDSNILVRQQYEANV KFFYNTDVIIANLSNAQPLVKAINNWVNNITNANIDRIIEDDNSVKNSLMLIVNTLFFKGLWRGKYFSPENTRNGKFYLI DNRTVDTSIMHAYGRFYYVESSDLDAKILRIPYDGQFAIYLLLPRIINGIDELIDKINPFVLTRYMWLMQDLSVDVLIPK FKFDFSSHLESILRELGICDIFDDTATLTGIAQTKRTSKRLKVSNILQKAGIEINENGTTAYVATEIEIGNKNQDETFHA NHPFLFYIEDESIGTIIYIGKIMNPLDTMDNVKIK >AAS13528.1 serine or cysteine protease inhibitor [Caenorhabditis elegans] MSDNATSQTDFALKLLATLPHSGSVVLSPLSISLGLALIHAGACGSTQKELEDVLGGSRIFEEFSGLMEAVGDTDNGVET KIVNRVFVNQAYTIHQDYLETVEKLYKASGESLDFSQTEQAAKTMNTFVENHTNGKIKDLIPADSANNAFAFLVNAMYFK ADWQSKFAKESTTGREFFTSEAESRQIPFLTDVDEHRDYTEDVLFQVLSLKYADPKFTLAIFLPKQRFGLVDALEKINGE YIQNLLNDLKSSYVSVQIPKFKIEKELDLKETLEAIGIKEIFAEGADLSGIADKVFISSGIHKAIIEVDEDGTTAAAASA FKVQLEMMIMAEPTQFVADHPFLFAVLFENHTLFLGVHA
Mafft alignment of selected proteins >sp|Q9UK55|ZPI_HUMAN Protein Z-dependent protease inhibitor OS=Homo sapiens OX=9606 GN=SERPINA10 PE=1 SV=1 ----------------------------------------MKVVPSLLLSVLLAQVWLVP GLAPSPQSPETPA------------PQNQTSRVV--QAPKEEEEDEQEASEEKASEEEKA WLMASRQ-QLAKETSN-----------FGFSLLRKISMR----HDGNMVFSPFGMSLAMT GLMLGATGPTETQIKRGLHLQA-------LK-PTKPGLLPSLFKGLRETL---------- -------SRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNA-SQAKRL MNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTP-FDPVFTEVDTFHLDKY KTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQG------NATMLVVLMEKMGDHLALEDY LTTDLVETWLRNMK-----TRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFS-PFADLSE LS---ATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSM----PPVIKVDRPFHF MIYEETSGMLLFLGRVVNPTLL-------- >tr|Q5RIH8|Q5RIH8_DANRE Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10a OS=Danio rerio OX=7955 GN=serpina10a PE=3 SV=1 ----------------------------------------MKMGFFTLLIEASL------ ------------------------------------------------------LSVSVL GQTTDVE-ELAIKNAD-----------FATRLYSKIASS----SDDNVAVSTLGATLALA TLAAGAGGATQSELLQGIGVDS-------MVKDGEQERIQNILQQLREDA---------- -------AQ------IPATGLFIKQDVKADDSFSNQVKQYYNADVQNVNYANG-QQAKGS INDYVRGRTGEKVRDVVEN--VDPQSMAILISAAFFTGQWLQP-FNATFTQEDRFYVNKY NIVQVPMMLRSGKYYLAYDPTFKVGILKLPCEN------GIAMLVLLPDEDVDYTYVDES MTGEVFRGWVAKLK-----KTKLEIQLPRFSLKQSNSLSVSLPSLGVKEIFG-STANLTG IS----SSEGLKLSEVVQKVAVDVDESGGSLAEASG-NLFMNPL----PPRLTFNRPFIF VVYHEVTKCILYIGRVVDPTKN-------- >NP_598301.2 protein Z-dependent protease inhibitor precursor [Rattus norvegicus] ----------------------------------------MRVVSSLFLPVLLAEVWLVS SFNLSSHSPEAPIRLVS------QDYENQTWEEYEWADPRD---------------DNEY WLRAS-Q-QLSNETSS-----------FGFSLLRKISMR----HDGNVIFSPFGLSVAMV NLMLGAKGETKVQVENGLNLQA-------LS-QAGPLILPALFKRVKETF---------- -------SSNKKLGLTQGSFAFIHKDFEIKKTYFNLSTMYFDTEYVPTNFRNS-SQARGL MNHYINKETEGKIPKLFDE--INPETKLILVDYILFKGKWLTP-FDPIFTEADTFHLDKY KAVKVPMMYREGNFASTFDKKFRCHILKLPYQG------NATMLVVLMEKSGDHLALEDY LTTDLVEMWLQDMK-----TRKMEVFFPKFKLNQRYEMHELLKQVGIRRIFS-TSADLSE LS---AVARNLQVSKVVQQSVLEVDERGTEVVSGTVSEITAYCM----PPVIKVDRPFHF IIYEEMSQMLLFLGRVVNPTVL-------- >NP_659083.2 protein Z-dependent protease inhibitor isoform 1 precursor [Mus musculus] ----------------------------------------MRVASSLFLPVLLTEVWLVT SFNLSSHSPEASVHLES------QDYENQTWEEYTRTDPREEEEEEEEK---EEGKDEEY WLRAS-Q-QLSNETSS-----------FGFNLLRKISMR----HDGNVIFSPFGLSVAMV NLMLGTKGETKVQIENGLNLQA-------LS-QAGPLILPALFKKVKETF---------- -------SSNRDLGLSQGSFAFIHKDFDIKETYFNLSKKYFDIEYVSINFQNS-SQARGL INHCIVKETEGKIPKLFDE--INPETKLILVDYVLFKGKWLTP-FDPSFTEADTFHLDKY RAIKVPMMYREGNFTSTFDKKFRCHILKLPYQG------NATMLVVLMEKTGDYLALEDY LTVDLVETWLQNMK-----TRKMEVFFPKFKLNQRYEMHELLKQMGIRRLFS-TSADLSE LS---AMARNLQVSRVLQQSVLEVDERGTEAVSGTLSEIIAYSM----PPAIKVNRPFHF IIYEEMSRMLLFLGRVVNPTVL-------- >XP_015143253.1 protein Z-dependent protease inhibitor [Gallus gallus] ----------------------------------------MKIRIYLLLLCELC--FEIS KADIKPKSPKKDKRLNFL----GRNKNVSISEEW--HQHKNDH----------KPLEEQS FEELTLH-NFTEKTAN-----------FGFNLYRKIAMK----LDNNIIISPLSVTTLMA TYLLAAEGETHRQIAKALNLHS-------LKDR-DRHYLPALFKQLKDNI---------- -------TTNEELLFVQGILSFIQKDFTVREAFLNLSKQYFDMEFLCVDFQNS-TQAKFV INQNIKQRTKGKISELFEE--VDRHSKLLLLDYIFFKGKWLYP-FNSEFTEIETFHINKY RSVQVPMMFKSDKVNSTYDENLRCNVIKLPYKG------KAYMLIVIPEKGEDYVSLEDH LTMELVESWLANMK-----SRNMDISFPKFKLEQKYKMKKLLYALGIKNLFA-RTADLSH LT----DQKHLTVSQVVQKAVIEVDEKGTEAAAATGSEIIAFSV----PPVLKVDRPFLF MIFEETFKTLLFIGRVVDPTET-------- >XP_024204665.1 protein Z-dependent protease inhibitor isoform X1 [Pan troglodytes] MSRSAQELLGYHCRLQDKLQEQEGSLAAEGRHSLASAADHMKVVPSLLLSVLLAQVWLVP GLAPSPQSPETPA------------PQNQTSRVV--QAPREEEEDEQEASEEKASEEEKA WLMASRQ-QLAKETSN-----------FGFSLLRKISMR----HDGNMVFSPFGMSLAMT GLMLGASGPTETQIKRGLHLQA-------LK-PTKPGLLPSLFKGLRETL---------- -------SHNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNA-SQAKRL MNHYINKETGGKIPKLFDE--IDPETKLILVDYILFKGKWLTP-FDPVFTEVDTFHLDKY KTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQG------NATMLVVLMEKMGDHLALEDY LTTDLVETWLRNMK-----TRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFS-PFADLSE LS---ATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSM----PPVIKVDRPFHF MIYEETSGMLLFLGRVVNPTLL-------- >NP_001092467.1 protein Z-dependent protease inhibitor precursor [Bos taurus] ----------------------------------------MWAVLSLPLACLLAQAWLVP GSTLASHSPEAQAGLETLLTPMAQNKTSQTSERQ--WAPEEEEE----------REEDSP WLLAEGQ-QLSREASN-----------LGFSLLRKISLK----HDGNVVFSPLGLAWAMA ALTLGARGHSRAQLED-LLLQAWNQTWPVVN-QTRPPRLPALFKQLQESL---------- -------SHNPELGLAQGSFAFIHKDFDIRETFLNLSKRYFDMECVTVDFHNT-SQAKRL INHYMNQETQGKLPKLFDE--INPDTKLILVDYILFKGKWLIP-FDPALTEMDTFYLDKY KEVKVPMMYRSGKFASTFDKKFHCHVLKLPYRG------NASMLVVLVERIGDHLTLEDY LTTDLVDTWLRNMK-----TRKMEVFFPKFKLDQKYKMHELLKQMGVQKIFL-PWADLSD LM---VTERNLKVSKVLQRATIEVDEEGTEAMAGTLLEITAYYM----PPIVKVDRPFLF IIYEETSRTVLFLGRVVDPTLL-------- >NP_001125107.1 protein Z-dependent protease inhibitor precursor [Pongo abelii] ----------------------------------------MKVVPSLLLSVLLAQVWLVP GLAPSPQSPETPA------------PQNQTSRVV--QAPREEEEDEQEASEEKAGDEEKA WLTASRQ-QLAKETSN-----------FGFSLLRKISMR----HDGNIVFSPFGTSLAMT GLMLGATGLTETQIKRGLHLQA-------LN-PTKPGLLPSLFKGLRETL---------- -------SRNLELGLTQGSFAFIHKDFDVKETFLNLSKRYFDTECVPMNFRNA-SQAKRL MNHYINKETRGKIPKLFDE--INPETKLILVDYILFKGKWLTP-FDPVFTEVDTFHQDKY KTIKVPMMYGAGKFASTFDKNFCCHVLKLPYQG------NVTMLVVLMEKMGDQLALEDY LTTDLVETWLRNMK-----TRNMEVFFPKFKLDQKYEMHELLRQMGIRRI-S-PFADLSE LS---ATGRNLQVSRVLQRTVIEVDERGTEAVAAILSEIIAYSM----PPAIKVDRPFHF MIYEETSGMLLFLGRVVNPTLL-------- >XP_010710160.1 protein Z-dependent protease inhibitor [Meleagris gallopavo] ----------------------------------------MKIGIYLLLLCEIC--FEIS KADIKPKSPKKDKRLNFL----GKNKNNSISEEW--HQHKNYS----------EPLEDES FEELTLH-NFTEKTAN-----------FGFNLYRKIAMK----LDNNIIISPLSVSTLMA TYLLAAEGETHRQIAKALNLHP-------LEDR-DRHYLPTLFKQLKDNI---------- -------TTNEELLFVQGILSFIQKDFVVREAFLNLSKQYFDMEFLRVNFQNI-TQAKSV INQNIKQRTKGKISELFEE--VDRHSKLLLLDYIFFKGKWLYP-FNSEFTEIETFHINKY RSVQVPMMFKSDKVNSTYDENLRCNVIKLPYKG------KAYMLIVIPEKGEDYVSLEDH LTMELVESWLANMK-----SRNTDISFPKFKLEQKYKMKKWLYALGIKNLFA-RTADLSH LT----DQKYVTVSQVVQKAVIEVDEKGTEAAAATGSEIIAFSA----PPVIKVDRPFLF MIFEETFKTLLFIGRVVDPTEM-------- >XP_027813160.1 protein Z-dependent protease inhibitor isoform X1 [Ovis aries] ----------------------------------------MRVVLSLPLACLLAQAWLAP GSTLASHSPEAQEGLETLLTPRAQNKTSQTSERP--WAPDEEKG-----------EEDSP WLSAKGQ-QFSREASN-----------LGFSLLRKISLK----HDGNVVFSPLGLAWAMA ALTLGARGHSRAQLEG-LLLQAWNQTRPAVN-QTRTPRLPALFKRLRESL---------- -------SHNPELGLAQGSFAFIHKDFDIRETFLNLSKRYFDMECVTVNFRNT-SQAKRL MNHYVNQETQGKLPKLFDE--INPDTRLILVDYILFKGKWLIP-FDPALTEMDTFYLDKY KVVKVPMMYRSGKFASTFDKNFGCHVLKLPYRG------NASMLVVLMGRIGDHLTLEDY LTTDLVDTWLRNMK-----TRKMEVFFPKFKLDQKYKMHELLKQMGVQRIFL-PWADLRD LT---VTERNLKVSKVLQRAMIEVDEEGTEAMAGTLLEITAYYM----PPIIRVDRPFLF IIYEETSRTVLFLGRVVNPTLL-------- >XP_004055674.1 protein Z-dependent protease inhibitor isoform X1 [Gorilla gorilla gorilla] MSRSAQELLGYHCRLQDKLQKQEGSLAAEGRHSLASTADHMKVVPSLLLSVLLAQVWLVP GLAPSPQSPETPA------------PQNQTSRVV--QAPREEEEDEQEASEEKASEEEKA WLMASRQ-QLAKETSN-----------FGFSLLRKISMR----HDGNMVFSPFGMSLAMT GLMLGATGPTETQIKRGLHLQA-------LK-PTKPGLLPSLFKGLRDSL---------- -------SHNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNA-SQAKRL MNHYINKETGGKIPKLFDE--IDPETKLILVDYILFKGKWLTP-FDPVFTEVDTFHLDKY KTIKVPMMYGAGKFASTFDKNFHCHVLKLPYQG------NATMLVVLVEKMGDHLALEDY LTTDLVETWLRNMK-----TRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFS-PFADLSE LS---ATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSM----PPVIKVDRPFHF MIYEETSGMLLFLGRVVNPTLL-------- >XP_005506179.1 protein Z-dependent protease inhibitor isoform X1 [Columba livia] MLHFCYE------RRT----------TKKQKNSLLDVN--MKTGIYLLVLSEIC--VEIS KASIKLKTPQKEKENKFW----EINNNVNIAEDW--HNHKNMS----------KPFEKQG LEDFTLY-NFTEKTAN-----------FGFNLYRKIAMT----HDNNVIISPLSVSTLMT AYMLAAKGETHRQIAKGLNLHA-------LKDTVDRHHLPALFKQLKDNI---------- -------TMNDEL-LVQGTLSFIQKDFRLKESFLNLSKQYFDMEFLRVDFQNF-TQAKLV INQNIKKRTKGKIPELFEE--LDRHTKLLLVDYIVFKGKWVYP-FNSKFTEMETFHINKY RSVQVPMMFKSDKVNSTFDENLRCTVIKLPYKG------KAHMLIVIPEKEGDYISLEDH LTTEVVEFWLGNMK-----TRKVDISFPKFKLEQKYKLKKLLHALGIKNLFT-RMADLGH LT----DQGYVAVSQVVQKAVIEVDEEGTEATAASGSEITAFTV----PPVIKVDRPFLF MIFEETFKTLLFIGRVVDPTEM-------- >XP_005695405.1 PREDICTED: protein Z-dependent protease inhibitor [Capra hircus] ----------------------------------------MRVVLSLPLACLLAQAWLAP GSTLASHSPEAQEGLETLLTPRAQNKTSQTSERP--WAPEEEEG-----------EEDSP WLSAKGQ-QFSREASN-----------LGFSLLRKISLK----HDGNVVFSPLGLAWAMA ALTLGARGHSRAQLEG-LFLQAWNQTWPAVN-QTRTPHLPALFKRLRESL---------- -------SHNPELGLAQGSFAFIHKDFDIRETFLNLSKRYFDMECVTVNFRNT-SQAKRL MNHYVNQETQGKLPKLFDE--INPDTRLILVDYILFKGKWLIP-FDPALTEMDTFYLDKY KVVKVPMMYRSGKFASTFDKNFGCRVLKLPYRG------NASMLVVLMGRIGDHLTLEDY LTTDLVDTWLRNMK-----TRKMEVFFPKFKLDQKYKMHELLKQMGVQRIFL-PWADLRD LT---VTERNLKVSKVLQRAMIEVDEEGTEATAGTLLEITAYYM----PPIIRVDRPFLF IIYEETSRTVLFLGRVVNPTLL-------- >XP_006025546.1 protein Z-dependent protease inhibitor [Alligator sinensis] ----------------------------------------MKTGICLLLLWEMC--LGMN TSSVKTRMPEKNKE-HFL----SKKQTFSISEEH--FHHKNIP----------KPFEVQV PLESTVY-NVTEKSTN-----------FGFNLYRKIAMQ----HDNNVLFSPLSLSFLMA AFMLGTKGETNNQIVQGLNLHL-------LKDKENPYHLPALFKQLKENI---------- -------TANEEFILQQGSFAFIQKDFCLNESFLNLSKEYFDMEFRSVDFNNS-TQAKEV INQNVNKMTKGKIQELFED--FDTHAKLVLVDYVFFKGKWIHP-FNARLTEPEFFHIDKY RSVQVPMMFKSDKVASTFDENLRCTVVKLPYKG------RVHLLIAVPEKEGDYVSLEDH LTAELVELWLRNMK-----TRKIDFFLPKFKLDQNYQMHKLLQTLGIKNLFT-NQADLSQ LT----DQMYARVSQVIQRAVIEVDERGTEAAAASGSEMTAYSV----PPTIRVNRPFLF MVFEETFKTLIFMGRVVNPTEL-------- >XP_006266325.1 PREDICTED: protein Z-dependent protease inhibitor [Alligator mississippiensis] ----------------------------------------MKTGICLLLLWEMC--LGMN TSSVKTRMPEKNKE-HFL----SKKQTFSISEEH--FHHKNIP----------KPFEVQV PLESTVY-NVTEKSTN-----------FGFNLYRKIAMQ----HDNNVLFSPLSLSFLMA AFMLGTKGETNNQIVQGLNLHL-------LKDEENPYHLPALFKQLKENI---------- -------TANEEFILQQGSFAFIQKDFCLNESFLNLSKEYFDMEFRSVDFNNS-TQAKEV INQNVNKMTKGKIQELFED--FDTRAKLVLVDYVFFKGKWLHP-FNARLTEPEFFHIDKY RSVQVPMMFKSDKVASTFDENLRCTVVKLPYKG------RVHLLIAVPEKEGDYVSLEDH LTAELVELWLRNMK-----TRKIDFFLPKFKLDQNYQMHKLLQTLGIKNLFT-NQADLSQ LT----DQMYARVSQVIQRAVIEVDERGTEAAAASGSEMTAYSV----PPTIRVNRPFLF MLFEETFKTLIFMGRVVNPTEL-------- >XP_008956493.1 protein Z-dependent protease inhibitor isoform X1 [Pan paniscus] MSRSAQELLGYHCRLQDKLQKQEGSLAAEGRHSLASAADHMKVVPSLLLSVLLAQVWLVP GLAPSPQSPETPA------------PQNQTSRVV--QAPREEEEDEQEASEEKASEEEKA WLMASRQ-QLAKETSN-----------FGFSLLRKISMR----HDGNMVFSPFGMSLAMT GLMLGASGPTETQIKRGLHLQA-------LK-PTKPGLLPSLFKGLRETL---------- -------SHNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECVPMNFRNA-SQAKRL MNHYINKETGGKIPKLFDE--IDPETKLILVDYILFKGKWLTP-FDPVFTEVDTFHLDKY KTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQG------NATMLVVLMEKMGDHLALEDY LTTDLVETWLRNMK-----TRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFS-PFADLSE LS---ATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSM----PPVIKVDRPFHF MIYEETSGMLLFLGRVVNPTLL-------- >XP_020754828.1 protein Z-dependent protease inhibitor [Odocoileus virginianus texanus] ----------------------------------------MRVVLSLPLACLLAQAWLAP GSTLASRSLEVQAGLETLLTARAQNKTNQTRERL--WAPEEEEG-----------EEDSP WLSTEGQ-KLSWEASN-----------LGFSLLRKISLK----HDGNVVFSPLGLAWAMA ALTLGAGGHSRAQLEE-LLSQT-------LN-QTRPPRLPALFKRLRESL---------- -------SHNPELGLAQGSFAFIHNDFDIRETFLNLSKRYFDTECVTVNFRNT-SQAKRL MNHYMNQQTQGKLPKLFDE--INPDTELILVDYILFKGKWLIP-FDPALTEMDTFYLDKY KTVKVPMMYRSGKFASTFDKNFRCHVLKLPYRG------NASMLVVLMGRIGDHLTLEDY LTTDLVDTWLRNMK-----ARKMEVFFPKFKLDQKYKMHELLKQMGVRKIFS-PWADLSN LA---VTERNLKVSKVLQRAMIEVDEEGTEAMAGTLSEITAYYM----PPIIRVDRPFLF IVYEETSRTVLFLGRVVNPTLL-------- >XP_040188191.1 protein Z-dependent protease inhibitor [Rana temporaria] ----------------------------------------MRWTFVFILLFGLT-----S AHQPTKGKPKKEK-----------------------HHQEKMPLL-----EESTLNLLNG TREISAL-DLSNMNNN-----------FGFNLYRRTADK----HDDNIFFSPLSVSFLLG ALTLGSRGMTHEQLLSGLGWEP-------FK--KNPDVLHTLLKDLKDGV---------- -------MKSDGYSLDVADLALLHESFDLNPEFLNQTMTYFHMEFQSVDFHD--RHVLET IRDLIRLKTRGRISELQDE--IDPQTKMMLLNFIFFKGKWQTP-FKSDSTQADTFYVNKY SSVKVPMMCKTEKVAAMFDKSLSCTVLKLPYRG------GAHMLVVMPQNDGNFDALEDG LSSELVASWLRKMK-----FRETEIFFPKFQLDHKYKMKSSLDELGIKDIFT-GRANLTG VT----EERNLMLSEVTQRAVIDIDEIGTEATAVTGAEMVPYFL----PYTIRINQPFIF MIFDEKFKSLLFIGRVTDPTKH-------- >KAF4018099.1 hypothetical protein G4228_009825 [Cervus hanglu yarkandensis] ----------------------------------------MWAVLSLPLACLLAQAWLAP GSTLASRSPEVQAGLETLLTARAQNKTNQTSERL--WAPEEEEG-----------EEDSP WLSTEGQ-KLSREASN-----------LGFSLLRKISLK----HDGNVVFSPLGLAWAMA ALTLGAGGHSRAQLEE-LLLQT-------LN-QTRPPRLPALFKRLRESL---------- -------SHNPELGLAQGSFAFIHKDFDIRETFLNLSKRYFDMECVTVNFRNT-SQAKSL MNHYMNQQTQGKLPKLFDE--INPDTELILVDYILFKGKWLIP-FDPALTEMDTFYLDKY KTVKVPMMYKSGKFASTFDKNFRCHVLKLPYRG------NASMLVVLMGRIGDHLALEDY LTTDLVDVWLRNMK-----ARKMEVFFPKFKLDQKYKMHELLKQMGVRKIFS-PWADLSN LA---ATERNLKVSKVLQRAMIEVDEEGTEAMAGTLSEITAYYM----PPIIRVDRPFLF IVYEETSRTVLFLGRVVNPTLL-------- >KAB0352921.1 hypothetical protein FD754_017778 [Muntiacus muntjak] ----------------------------------------MWAVLSLPLACLLAQAWLAP GSTLASRSPEVQAGLETLLTARAQSKTSQTSERR--RAPEEEEG-----------EEDSP WLSPEGQ-KLSGEASN-----------LGFSLLRKISLK----HDGNVVFSPLGLAWAMA ALTLGARGHSRAQLEE-PLLQT-------LN-QTRPPRLPALFKRLRDSL---------- -------SHNPELGLAQGSFAFIHKDFDIRETFLNLSKTYFDTECVTVNFRNT-SQAKRL MNHYMNQQTQGKLPKLFDE--INPDTELILVDYILFKGKWLIP-FDPALTEMDTFYLDKY KTVKVPMMYRSGKFASTFDTNFRCHVLKLPYRG------NASMLVVLMG-IGDHLTLEDY LTTDLVDAWLRNMK-----ARKMEVFFPKFKLDQKYKMHELLKQMGVQKIFS-PWSDLSN LA---VTERNLKVSKILQRAMIEVDEEGTEAMAGTLSEITAYYM----PPVIKVDRPFLF IVYEETSRTVLFLGRVVNPTLL-------- >XP_043346178.1 protein Z-dependent protease inhibitor [Cervus canadensis] ----------------------------------------MWAVLSLLLACLLAQAWLAP GSTLASRSPEVQAGLQTLLTARAQNKTNQTSERL--WAPEEEEG-----------EEDSP WLSTEGQ-KLSREASN-----------LGFSLLRKISLK----HDGNVVFSPLGLAWAMA ALTLGAGGHSRAQLEE-LLLQT-------LN-QTRPPRLPALFKQLRESL---------- -------SHNPELGLAQGSFAFIHKDFDIRETFLNLSKRYFDMECVTVNFRNT-SQAKSL MNHYMNQQTQGKLPKLFDE--INPDTELILVDYILFKGKWLIP-FDPALTEMDTFYLDKY KTVKVPMMYKSGKFASTFDKNFRCHVLKLPYRG------NASMLVVLMGRIGDHLTLEDY LTTDLVDVWLRNMK-----ARKMEVFFPKFKLDQKYKMHELLKQMGVRKIFS-PWADLSN LA---ATERNLKVSKVLQRAMIEVDEEGTEAMAGTLSEITAYYM----PPIIRVDRPFLF IVYEETSRTVLFLGRVVNPTLL-------- >XP_043778021.1 protein Z-dependent protease inhibitor [Cervus elaphus] ----------------------------------------MWAVLSLLLACLLAQAWLAP GSTLASRSPEVQAGLETLLTARAQNKTNQTSERL--WAPEEEEG-----------EEDSP WLSTEGQ-KLSREASN-----------LGFSLLRKISLK----HDGNVVFSPLGLAWAMA ALTLGAGGHSRAQLEE-LLLQT-------LN-QTLPPRLPALFKQLRESL---------- -------SHNPELGLAQGSFAFIHKDFDIRETFLNLSKRYFDMECVTVNFRNT-SQAKSL MNHYMNQQTQGKLPKLFDE--INPDTELILVDYILFKGKWLIP-FDPALTEMDTFYLDKY KTVKVPMMYKSGKFASTFDKNFRCHVLKLPYRG------NASMLVVLMGRIGDHLTLEDY LTTDLVDVWLRNMK-----ARKMEVFFPKFKLDQKYKMHELLKQMGVRKIFS-PWADLSN LA---ATERNLKVSKVLQRAMIEVDEEGTEAMAGTLSEITAYYM----PPIIRVDRPFLF IVYEETSRTVLFLGRVVNPTLL-------- >KAB0369185.1 hypothetical protein FD755_019190 [Muntiacus reevesi] ----------------------------------------MWAVLSLPLACLLAQAWLAP GSTLASRSPEVQAGLETLLTARAQNKTNQTSERL--WAPEEEEG-----------EEDSP WLSPEGQ-KLSGEASN-----------LGFSLLRKISLK----HDGNVVFSPLGLAWAMA ALTLGARGHSRAQLEE-LLLQT-------LN-QTRPPRLPALFKRLRESL---------- -------SHNPELGLAQGSFAFIHKDFDIRETFLNLSKRYFDTECVTVNFRNT-SQAKRL MNHYMNQQTQGKLPKLFDE--INPDTELILVDYILFKGKWLIP-FDPALTEMDTFYLDKY KTVKVPMMYRSGKFASTFDTNFRCHVLKLPYRG------NASMLVVLMG-IGDHLTLEDY LTTDLVDTWLRNMK-----ARKMEVFFPKFKLDQRYKMHELLKQMGVRKIFS-PWSDLSN LA---VTERNLKVSKILQRAMIEVDEEGTEAMAGTLSEITAYYM----PPVIKVDRPFLF IVYEETSRTVLFLGRVVNPTLL-------- >OCT68273.1 hypothetical protein XELAEV_18039571mg [Xenopus laevis] ----------------------------------------MKHRLCLLLPFLLTG-LCFA DHAIKQHKPSRKQRLDE------SEWNKQISAAT--VMDSMNT----------STNDQQI PPVLSVS-NVSQMISD-----------FGFNLYRKIANK----HDDNIFFSPFSVSLGLS SLLLGTRGNTYDQLLHGLNYNR-------FKEQENPYLLPELLKTIKEKI---------- -------AQNEELVLNIGSLSFLHETFSMKEEFINLTKTYFDMEYEFIDFHS--SKAKNE INAHVEKLTKGLISNFYDF--LDPQTKLLLLDYIFFKGKWQYP-FNPALTEEDTFFIDKY NSVTVPMMYKSDKVASLLDKDLSCTVFKLPYRG------NAHMLIIKPEKEGDFGILEDH LTKELIDSWLAKMQ-----SRKTDIFFPKFKLDQKYKLKSSLNELGIKELFT-GRANLTD LT----EERNLLLTEVTQQAIIDVNERGTEAAAAAGAEIIAYSL----PLTIRVNRPFLF LIYEEAFQSLLFIGRVTNPTKL-------- >XP_004082346.1 protein Z-dependent protease inhibitor isoform X1 [Oryzias latipes] --------------------------------MVFNG---IKMLVVFALTCMCF------ ----------------------------------------------------IVPVHQSL LPNATIL-DLSYKNMD-----------FAMNLYRKIANY----HDKNIFFSPLSVSTSFA ALLMASDGITHQEILKVCNLEQ-------FEMVDQPQLIPRLFQDLQENI---------- -------SRNGSLQLEQSMALFIRQRFEVEKTFQDNLKNFFQADINVLNFGNT-KDSIKT INDYVRQKTADKVPEMIST--LNAMTKLLLINTIFFQGVWQIP-FNPNFTENAPFHIDNY NIVQVPMMFVEDKFYTMEDEPLGARVLKLPYKE------GVSMLILLPNKKTDYTTIDNE ITAQRFLSWIRNLE-----PMKLEVNMPKFKMERAYSLHNILPEMGMSSLFT-DFANLTR LS----KAQALRVSEVLHKAVIEVDEVGTTAAAATATGIIPYAL----PRRFTINRPFFF FIYHEETNALLFMGRVINPTKN-------- >XP_015825579.1 PREDICTED: protein Z-dependent protease inhibitor-like [Nothobranchius furzeri] ---------------------------------MVPK---IKMAFLVVLACLCF------ ----------------------------------------------------FTPTHQSP PPNAAIL-ELSYENTD-----------FAMNLYRKLANY----NDKNIFFSPLSVSTTFA SLLMASGGITREEILRGLDLNQ-------LE-TNQTEHIPKLFQLLQENI---------- -------AQNGSLKLEQSMALFISQQFEVKKTFEDRLKTFFQADIRTVDFAES-TKSITL INEYIKQKTGGKIVKMIST--LDETTRLLLINSIYFQGAWKNP-FNPNLTESAAFHIDNY NVVQVSMMMKEARFFVTEDVLLGARVLKLPYQD------GVSMLILLPNKNVDYTSIDEE ISAEKFSSWIEGLR-----KTKLEVHVPKFKMEQAYALQNILPDMGMTSLFS-TSANLTG IG----EGQDLMVSEVLHKAVIEVDETGTTAAAATTVGITPYSL----PRMFIVDRPFFF FIYHEETKSLLFMGRVIDPTKN-------- >XP_030247366.1 protein Z-dependent protease inhibitor-like isoform X2 [Sparus aurata] MFEPPY--------------------LSQTPNMVVHK---MKMGFIPIVTFMCF------ ----------------------------------------------------LAPLQQAH APSATIA-DLSFKNMD-----------FAMELYRKISSF----HDKNIFFSPLSISTSFA ALLMASDGVTRDEMLRGLNLEQ-------LEQADQPELIPKLFQLLNENI---------- -------TQNGSLKLDQGMALFMAPQFEVQNMFEDQIKEFFSADIKSVNFGDT-KGAIRF INEYVKHRTHDKVTEMISS--LDSATKLMLINTIFFQGAWQMP-FNPNFTESAPFYIDNY SVVQVPMMFMEDKFYMMEDISLGAKGLKLPYQE------GVSMLILLPKKGVDYTVIDEE ITAEKFLSCIKKLQ-----KIKLEVHIPKFKMEQSYSLHNLLPEMGMASVFS-NSANLTK LS----KSGRLKVSEVLHKAVIEVDETGTTAAAATTIGITPFSL----PRTFTVNKPFFF FIYHEDTNCVLFMGRVIDPTKN-------- >XP_038050239.1 leukocyte elastase inhibitor-like [Patiria miniata] MY-----------KLTLLV-------TSSRPDSIM-----AVIQIISILTVIAL------ ----------------------------------------------------LYMSVFAT STGPDPQLELADANNR-----------FAFHLYQTLADD---PHRDNIFFSPMSISIALA MTSLGARGNTARQIKDVLKFST-------LE----ESRLHSSFAELNSAIFG-------- -------ANADKYVLRKANRLFGHKGFDLRQEFLADAERYYSSHMASLDFVEDTEVAREF INSWVGRETEDKIRDLLPHGSITGMTQLVLVNAIYFKADWVRQ-FDKSKTFDQDFHVSKD QVLEVPMMHRKSKFNFAEDITLRCKLIELPYVGQ-----DFSMIVVLPDEIDGIDRLQKH LTNEKLQHLLNNLS-----NVTVGVAIPKFKLEETLHMNDVLYSMGMRDLFVRDKADLSG IT----GTRDLFVSSVIHRAFLEVNEEGSEAAAATAVTINKRSISL--APEFIADHPFLF FIADSKTKAIVFMGHCRKPEGVS-LNHEEL >XP_031557330.1 leukocyte elastase inhibitor-like [Actinia tenebrosa] MG-------------NNII-------TCNT----------FRLHSVLILA-VSL------ ----------------------------------------------------VFCSVLLS TMAQA---DLIKASTN-------K---FSLHLHQVLRGQATFDAEQNLFYSPSSILVALA MTHLGARGNTAKQMSSSFHLDE-------IP----EKQLNAEFQKFLQKLNQ-------- -------SNAKGNEIAMANRLFVQMGFEVSKQFQEDSEKFFNAEAALVDYQKNSEGARQE VNQWVEQKTKNKIKDLIPEGMFGPDTRLTLVNAIYFKGSWMSK-FDSNNTQTGPFQLTPS KTVQVPMMYKSDKFKYFENEGLKCKMLELPYSDE-----KISMIILLPDEVDGLSKLEDS LNYSKLDEAIGHLKMAP--KEEVEVTLPKFKLSEKFSLKEVLSKMGASDLFNAAKADLTG IN----KDGQLYVSEVVHKAFVDVNEEGTEAAAATAVRVALMCMPM--NPIFFANHPFLF LIRHNESGAILFIGRLANPK---------- >XP_039269246.1 serpin B9-like [Styela clava] MI-----------KMKNII---------------------ISLGIAICLAVMSK------ --------------------------------------------------ADKMKTSTTP SDECSMA-SGAEANRI-----------FAYEMYKVAAKL---KPNQNIFLAPTTVGSGLS MMLPGARESTKDQMLEGLMFKN-------TSTGFEPNDIECLMKMYSNELIETKLEDRGK GTKDVKAAKEDTLQLRTANRLFGEKSFNFSSKFIEQTAK-YGVEMTKMNFQTDSAESRNF INQWVEKATEGKIKDLFSGKAIRPDTVLAVVSAIYFKGLWKYP-FDPLNTFKQDFKVNDN KTVKADFMTKMINYRMTYSEDLEAQILDVPYDGDAYGKYNASMILIVPTRRGSIERVEEM LSEKTMKPILDELQAEQQYTQRVRLLLPKFKMSKTYQLKPILRRLGIKNLFNPIRANLSG MIDPSEISPNLYVSTAVHKTFIKVDEKGTEAAGASGFGIVPLSL----PPRLFCNRPFLF MIYEKNTDGVLFIGKVNDPTVQ-------- >XP_030838146.1 leukocyte elastase inhibitor A isoform X3 [Strongylocentrotus purpuratus] MA--------------------------------------FHITMVTLLT-LGM------ ----------------------------------------------------MGSEVKAV EVGEHTQ-QLARANNA-----------FALHLYSATRAT---HPDQNLFFSPLSVSTALG MTHLGARGTSSAQMSEVLRFNL-------LE----EEHLHASFKQLNALLY--------- -------ESSNKYTLKSANKLFGKAGADFLQEFLDNTGNFYNSAFEAVKDFAA-PEARTM INDWVAKETEDKIQNLFPDGVLNSLTQLVLVNAIYFKSNWVKS-FNRDDTEPGVFRM-KD ETAHLPMMFKDGEVMMTDDKERKCFVLEMPYDGE-----DLSMLAILPWDDDGLANVEEQ LSMEVLDFWDSDLE-----PENAMYWVPRFKLEDTFSLSSILQSMGMADAFDATKADFSG MT----GDQSLHISEVIHKAFVEVNEEGTEAAAATGVTMTKRSISK--RYRLRFDHPFLF LIRDRRTKAVLFLGRLVDPPHDIRVHHEEL >NP_524953.1 serpin 55B [Drosophila melanogaster] M---------------------------------------FDFNL--------------- ------------------------------------------------------------ --------EFARGGAR-----------FTSELFQLLSAG---GLKENVVFSPFSIQTCIA LAFAGSQGETADEIAKALHFVS-----------NFPPEVAQTFQFVLEKYR--------- ----------NSNLLRVANKLYVQEGKQLKPAYQSAIKEQYHSEAESINFALN-DAAAQA INAWVNAKTQGKITELVSADSFSDNTRLVLLNALHFKGSWAHK-FSEERTEEDIFWVGEE EQVKINYMNQKAKFNYGFFEDLGCTALEMPYQDS-----DLSMFVLLPQERTGIYALAEK LKTVNLVDLADKLT-----VEEVHVKFPKFKVDYSLELAEKLKQLGITKMFT-DQAEFSN LL---ESPEGVFVSKVLHKATIEVNEEGTEAAAATGMIMMTRMMTF--PLQFQADRPFLY VIWNKKN--ILFAGAFVKAA---------- >XP_016773435.2 serine protease inhibitor 27A isoform X2 [Apis mellifera] MC---Y----------------------------------LIVTYIIILTLKQC------ KSEIMNNKSQS-----------------------------------------IFDTNVTR NINHEII-NHNKTNNDFVPYQGERFDIFDWTFFKSISKK----YSKNVIISPISLKIALV LLYEGAQGETAYELANILQLPA-------TR-----NATRKKFSNILQSLQ--------- -------TNFTAYTLNIGTRIYIDSNILVRQQYEANVKFFYNTDVIIANLSNA-QPLVKA INNWVNNITNANIDRIIEDDNSVKNSLMLIVNTLFFKGLWRGKYFSPENTRNGKFYLIDN RTVDTSIMHAYGRFYYVESSDLDAKILRIPYDG------QFAIYLLLPRIINGIDELIDK INPFVLTRYMWLMQ-----DLSVDVLIPKFKFDFSSHLESILRELGICDIFD-DTATLTG IAQTKRTSKRLKVSNILQKAGIEINENGTTAYVATEIEIGNKNQ----DETFHANHPFLF YIEDESIGTIIYIGKIMNPLDTM-DNVKIK >AAS13528.1 serine or cysteine protease inhibitor [Caenorhabditis elegans] MS---------------------------------------------------------- ------------------------------------------------------------ --------DNATSQTD-----------FALKLLATL------PHSGSVVLSPLSISLGLA LIHAGACGSTQKELEDVLGGSR----------------IFEEFSGLMEAVG--------- -------DTDNGVETKIVNRVFVNQAYTIHQDYLETVEKLYKASGESLDFSQT-EQAAKT MNTFVENHTNGKIKDLIPAD-SANNAFAFLVNAMYFKADWQSK-FAKESTTGREFFTSEA ESRQIPFLTDVDEHR-DYTEDVLFQVLSLKYADP-----KFTLAIFLPKQRFGLVDALEK INGEYIQNLLNDLK-----SSYVSVQIPKFKIEKELDLKETLEAIGIKEIFA-EGADLSG IA------DKVFISSGIHKAIIEVDEDGTTAAAASAFKVQLEMMIMAEPTQFVADHPFLF AVLFENH--TLFLG----------VHA---
BMGE Cleaned alignment of selected proteins >sp|Q9UK55|ZPI_HUMAN Protein Z-dependent protease inhibitor OS=Homo sapiens OX=9606 GN=SERPINA10 PE=1 SV=1 MKVVPSLLLSVLLAQWLVPGLAPSPQSPETPA---PQNQTSRVVQAPKEEEFGFSLLRKISMHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQGLLPSLFKGLRETLLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECQAKRLMNHYINETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEALEDYLTTDLVWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSFADLSELSNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPTLL >tr|Q5RIH8|Q5RIH8_DANRE Serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10a OS=Danio rerio OX=7955 GN=serpina10a PE=3 SV=1 MKMGFFTLLIEASL-------------------------------------FATRLYSKIASSDDNVAVSTLGATLALATLAAGAGGATQSELLQGIGVDERIQNILQQLREDA-----IPATGLFIKQDVKADDSFSNQVKQYYNADVQAKGSINDYVRRTGEKVRDVVENVDPQSMAILISAAFFTGQWLQPFNATFTQERFYVNKYNIVQVPMMLRSGKYYLAYDPTFKVGILKLPCENGIAMLVLLPDYVDESMTGEVFWVAKLKKTKLEIQLPRFSLKQSNSLSVSLPSLGVKEIFGTANLTGISGLKLSEVVQKVAVDVDESGGSLAEASG-NLFMNPLPPRLTFNRPFIFVVYHEVTKCILYIGRVVDPTKN >NP_598301.2 protein Z-dependent protease inhibitor precursor [Rattus norvegicus] MRVVSSLFLPVLLAEWLVSSFNLSSHSPEAPIRQDYENQTWEEYADPRD--FGFSLLRKISMHDGNVIFSPFGLSVAMVNLMLGAKGETKVQVENGLNLQLILPALFKRVKETFKKLGLTQGSFAFIHKDFEIKKTYFNLSTMYFDTEYQARGLMNHYINETEGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPIFTEATFHLDKYKAVKVPMMYREGNFASTFDKKFRCHILKLPYQGNATMLVVLMEALEDYLTTDLVWLQDMKTRKMEVFFPKFKLNQRYEMHELLKQVGIRRIFSSADLSELSNLQVSKVVQQSVLEVDERGTEVVSGTVSEITAYCMPPVIKVDRPFHFIIYEEMSQMLLFLGRVVNPTVL >NP_659083.2 protein Z-dependent protease inhibitor isoform 1 precursor [Mus musculus] MRVASSLFLPVLLTEWLVTSFNLSSHSPEASVHQDYENQTWEEYTDPREEEFGFNLLRKISMHDGNVIFSPFGLSVAMVNLMLGTKGETKVQIENGLNLQLILPALFKKVKETFRDLGLSQGSFAFIHKDFDIKETYFNLSKKYFDIEYQARGLINHCIVETEGKIPKLFDEINPETKLILVDYVLFKGKWLTPFDPSFTEATFHLDKYRAIKVPMMYREGNFTSTFDKKFRCHILKLPYQGNATMLVVLMEALEDYLTVDLVWLQNMKTRKMEVFFPKFKLNQRYEMHELLKQMGIRRLFSSADLSELSNLQVSRVLQQSVLEVDERGTEAVSGTLSEIIAYSMPPAIKVNRPFHFIIYEEMSRMLLFLGRVVNPTVL >XP_015143253.1 protein Z-dependent protease inhibitor [Gallus gallus] MKIRIYLLLLCELC-FEISKADIKPKSPKKDKRRNKNVSISEEWHQHKNDHFGFNLYRKIAMLDNNIIISPLSVTTLMATYLLAAEGETHRQIAKALNLHHYLPALFKQLKDNIEELLFVQGILSFIQKDFTVREAFLNLSKQYFDMEFQAKFVINQNIKRTKGKISELFEEVDRHSKLLLLDYIFFKGKWLYPFNSEFTEITFHINKYRSVQVPMMFKSDKVNSTYDENLRCNVIKLPYKGKAYMLIVIPESLEDHLTMELVWLANMKSRNMDISFPKFKLEQKYKMKKLLYALGIKNLFATADLSHLTHLTVSQVVQKAVIEVDEKGTEAAAATGSEIIAFSVPPVLKVDRPFLFMIFEETFKTLLFIGRVVDPTET >XP_024204665.1 protein Z-dependent protease inhibitor isoform X1 [Pan troglodytes] MKVVPSLLLSVLLAQWLVPGLAPSPQSPETPA---PQNQTSRVVQAPREEEFGFSLLRKISMHDGNMVFSPFGMSLAMTGLMLGASGPTETQIKRGLHLQGLLPSLFKGLRETLLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECQAKRLMNHYINETGGKIPKLFDEIDPETKLILVDYILFKGKWLTPFDPVFTEVTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEALEDYLTTDLVWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSFADLSELSNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPTLL >NP_001092467.1 protein Z-dependent protease inhibitor precursor [Bos taurus] MWAVLSLPLACLLAQWLVPGSTLASHSPEAQAGQNKTSQTSERQWAPEEEELGFSLLRKISLHDGNVVFSPLGLAWAMAALTLGARGHSRAQLED-LLLQPRLPALFKQLQESLPELGLAQGSFAFIHKDFDIRETFLNLSKRYFDMECQAKRLINHYMNETQGKLPKLFDEINPDTKLILVDYILFKGKWLIPFDPALTEMTFYLDKYKEVKVPMMYRSGKFASTFDKKFHCHVLKLPYRGNASMLVVLVETLEDYLTTDLVWLRNMKTRKMEVFFPKFKLDQKYKMHELLKQMGVQKIFLWADLSDLMNLKVSKVLQRATIEVDEEGTEAMAGTLLEITAYYMPPIVKVDRPFLFIIYEETSRTVLFLGRVVDPTLL >NP_001125107.1 protein Z-dependent protease inhibitor precursor [Pongo abelii] MKVVPSLLLSVLLAQWLVPGLAPSPQSPETPA---PQNQTSRVVQAPREEEFGFSLLRKISMHDGNIVFSPFGTSLAMTGLMLGATGLTETQIKRGLHLQGLLPSLFKGLRETLLELGLTQGSFAFIHKDFDVKETFLNLSKRYFDTECQAKRLMNHYINETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPVFTEVTFHQDKYKTIKVPMMYGAGKFASTFDKNFCCHVLKLPYQGNVTMLVVLMEALEDYLTTDLVWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRI-SFADLSELSNLQVSRVLQRTVIEVDERGTEAVAAILSEIIAYSMPPAIKVDRPFHFMIYEETSGMLLFLGRVVNPTLL >XP_010710160.1 protein Z-dependent protease inhibitor [Meleagris gallopavo] MKIGIYLLLLCEIC-FEISKADIKPKSPKKDKRKNKNNSISEEWHQHKNYSFGFNLYRKIAMLDNNIIISPLSVSTLMATYLLAAEGETHRQIAKALNLHHYLPTLFKQLKDNIEELLFVQGILSFIQKDFVVREAFLNLSKQYFDMEFQAKSVINQNIKRTKGKISELFEEVDRHSKLLLLDYIFFKGKWLYPFNSEFTEITFHINKYRSVQVPMMFKSDKVNSTYDENLRCNVIKLPYKGKAYMLIVIPESLEDHLTMELVWLANMKSRNTDISFPKFKLEQKYKMKKWLYALGIKNLFATADLSHLTYVTVSQVVQKAVIEVDEKGTEAAAATGSEIIAFSAPPVIKVDRPFLFMIFEETFKTLLFIGRVVDPTEM >XP_027813160.1 protein Z-dependent protease inhibitor isoform X1 [Ovis aries] MRVVLSLPLACLLAQWLAPGSTLASHSPEAQEGQNKTSQTSERPWAPDEEKLGFSLLRKISLHDGNVVFSPLGLAWAMAALTLGARGHSRAQLEG-LLLQPRLPALFKRLRESLPELGLAQGSFAFIHKDFDIRETFLNLSKRYFDMECQAKRLMNHYVNETQGKLPKLFDEINPDTRLILVDYILFKGKWLIPFDPALTEMTFYLDKYKVVKVPMMYRSGKFASTFDKNFGCHVLKLPYRGNASMLVVLMGTLEDYLTTDLVWLRNMKTRKMEVFFPKFKLDQKYKMHELLKQMGVQRIFLWADLRDLTNLKVSKVLQRAMIEVDEEGTEAMAGTLLEITAYYMPPIIRVDRPFLFIIYEETSRTVLFLGRVVNPTLL >XP_004055674.1 protein Z-dependent protease inhibitor isoform X1 [Gorilla gorilla gorilla] MKVVPSLLLSVLLAQWLVPGLAPSPQSPETPA---PQNQTSRVVQAPREEEFGFSLLRKISMHDGNMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQGLLPSLFKGLRDSLLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECQAKRLMNHYINETGGKIPKLFDEIDPETKLILVDYILFKGKWLTPFDPVFTEVTFHLDKYKTIKVPMMYGAGKFASTFDKNFHCHVLKLPYQGNATMLVVLVEALEDYLTTDLVWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSFADLSELSNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPTLL >XP_005506179.1 protein Z-dependent protease inhibitor isoform X1 [Columba livia] MKTGIYLLVLSEIC-VEISKASIKLKTPQKEKEINNNVNIAEDWHNHKNMSFGFNLYRKIAMHDNNVIISPLSVSTLMTAYMLAAKGETHRQIAKGLNLHHHLPALFKQLKDNIDEL-LVQGTLSFIQKDFRLKESFLNLSKQYFDMEFQAKLVINQNIKRTKGKIPELFEELDRHTKLLLVDYIVFKGKWVYPFNSKFTEMTFHINKYRSVQVPMMFKSDKVNSTFDENLRCTVIKLPYKGKAHMLIVIPESLEDHLTTEVVWLGNMKTRKVDISFPKFKLEQKYKLKKLLHALGIKNLFTMADLGHLTYVAVSQVVQKAVIEVDEEGTEATAASGSEITAFTVPPVIKVDRPFLFMIFEETFKTLLFIGRVVDPTEM >XP_005695405.1 PREDICTED: protein Z-dependent protease inhibitor [Capra hircus] MRVVLSLPLACLLAQWLAPGSTLASHSPEAQEGQNKTSQTSERPWAPEEEELGFSLLRKISLHDGNVVFSPLGLAWAMAALTLGARGHSRAQLEG-LFLQPHLPALFKRLRESLPELGLAQGSFAFIHKDFDIRETFLNLSKRYFDMECQAKRLMNHYVNETQGKLPKLFDEINPDTRLILVDYILFKGKWLIPFDPALTEMTFYLDKYKVVKVPMMYRSGKFASTFDKNFGCRVLKLPYRGNASMLVVLMGTLEDYLTTDLVWLRNMKTRKMEVFFPKFKLDQKYKMHELLKQMGVQRIFLWADLRDLTNLKVSKVLQRAMIEVDEEGTEATAGTLLEITAYYMPPIIRVDRPFLFIIYEETSRTVLFLGRVVNPTLL >XP_006025546.1 protein Z-dependent protease inhibitor [Alligator sinensis] MKTGICLLLLWEMC-LGMNTSSVKTRMPEKNKEKKQTFSISEEHFHHKNIPFGFNLYRKIAMHDNNVLFSPLSLSFLMAAFMLGTKGETNNQIVQGLNLHYHLPALFKQLKENIEEFILQQGSFAFIQKDFCLNESFLNLSKEYFDMEFQAKEVINQNVNMTKGKIQELFEDFDTHAKLVLVDYVFFKGKWIHPFNARLTEPFFHIDKYRSVQVPMMFKSDKVASTFDENLRCTVVKLPYKGRVHLLIAVPESLEDHLTAELVWLRNMKTRKIDFFLPKFKLDQNYQMHKLLQTLGIKNLFTQADLSQLTYARVSQVIQRAVIEVDERGTEAAAASGSEMTAYSVPPTIRVNRPFLFMVFEETFKTLIFMGRVVNPTEL >XP_006266325.1 PREDICTED: protein Z-dependent protease inhibitor [Alligator mississippiensis] MKTGICLLLLWEMC-LGMNTSSVKTRMPEKNKEKKQTFSISEEHFHHKNIPFGFNLYRKIAMHDNNVLFSPLSLSFLMAAFMLGTKGETNNQIVQGLNLHYHLPALFKQLKENIEEFILQQGSFAFIQKDFCLNESFLNLSKEYFDMEFQAKEVINQNVNMTKGKIQELFEDFDTRAKLVLVDYVFFKGKWLHPFNARLTEPFFHIDKYRSVQVPMMFKSDKVASTFDENLRCTVVKLPYKGRVHLLIAVPESLEDHLTAELVWLRNMKTRKIDFFLPKFKLDQNYQMHKLLQTLGIKNLFTQADLSQLTYARVSQVIQRAVIEVDERGTEAAAASGSEMTAYSVPPTIRVNRPFLFMLFEETFKTLIFMGRVVNPTEL >XP_008956493.1 protein Z-dependent protease inhibitor isoform X1 [Pan paniscus] MKVVPSLLLSVLLAQWLVPGLAPSPQSPETPA---PQNQTSRVVQAPREEEFGFSLLRKISMHDGNMVFSPFGMSLAMTGLMLGASGPTETQIKRGLHLQGLLPSLFKGLRETLLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTECQAKRLMNHYINETGGKIPKLFDEIDPETKLILVDYILFKGKWLTPFDPVFTEVTFHLDKYKTIKVPMMYGAGKFASTFDKNFRCHVLKLPYQGNATMLVVLMEALEDYLTTDLVWLRNMKTRNMEVFFPKFKLDQKYEMHELLRQMGIRRIFSFADLSELSNLQVSRVLQRTVIEVDERGTEAVAGILSEITAYSMPPVIKVDRPFHFMIYEETSGMLLFLGRVVNPTLL >XP_020754828.1 protein Z-dependent protease inhibitor [Odocoileus virginianus texanus] MRVVLSLPLACLLAQWLAPGSTLASRSLEVQAGQNKTNQTRERLWAPEEEELGFSLLRKISLHDGNVVFSPLGLAWAMAALTLGAGGHSRAQLEE-LLSQPRLPALFKRLRESLPELGLAQGSFAFIHNDFDIRETFLNLSKRYFDTECQAKRLMNHYMNQTQGKLPKLFDEINPDTELILVDYILFKGKWLIPFDPALTEMTFYLDKYKTVKVPMMYRSGKFASTFDKNFRCHVLKLPYRGNASMLVVLMGTLEDYLTTDLVWLRNMKARKMEVFFPKFKLDQKYKMHELLKQMGVRKIFSWADLSNLANLKVSKVLQRAMIEVDEEGTEAMAGTLSEITAYYMPPIIRVDRPFLFIVYEETSRTVLFLGRVVNPTLL >XP_040188191.1 protein Z-dependent protease inhibitor [Rana temporaria] MRWTFVFILLFGLT----SAHQPTKGKPKKEK------------HHQEKMPFGFNLYRRTADHDDNIFFSPLSVSFLLGALTLGSRGMTHEQLLSGLGWEDVLHTLLKDLKDGVDGYSLDVADLALLHESFDLNPEFLNQTMTYFHMEFHVLETIRDLIRKTRGRISELQDEIDPQTKMMLLNFIFFKGKWQTPFKSDSTQATFYVNKYSSVKVPMMCKTEKVAAMFDKSLSCTVLKLPYRGGAHMLVVMPQALEDGLSSELVWLRKMKFRETEIFFPKFQLDHKYKMKSSLDELGIKDIFTRANLTGVTNLMLSEVTQRAVIDIDEIGTEATAVTGAEMVPYFLPYTIRINQPFIFMIFDEKFKSLLFIGRVTDPTKH >KAF4018099.1 hypothetical protein G4228_009825 [Cervus hanglu yarkandensis] MWAVLSLPLACLLAQWLAPGSTLASRSPEVQAGQNKTNQTSERLWAPEEEELGFSLLRKISLHDGNVVFSPLGLAWAMAALTLGAGGHSRAQLEE-LLLQPRLPALFKRLRESLPELGLAQGSFAFIHKDFDIRETFLNLSKRYFDMECQAKSLMNHYMNQTQGKLPKLFDEINPDTELILVDYILFKGKWLIPFDPALTEMTFYLDKYKTVKVPMMYKSGKFASTFDKNFRCHVLKLPYRGNASMLVVLMGALEDYLTTDLVWLRNMKARKMEVFFPKFKLDQKYKMHELLKQMGVRKIFSWADLSNLANLKVSKVLQRAMIEVDEEGTEAMAGTLSEITAYYMPPIIRVDRPFLFIVYEETSRTVLFLGRVVNPTLL >KAB0352921.1 hypothetical protein FD754_017778 [Muntiacus muntjak] MWAVLSLPLACLLAQWLAPGSTLASRSPEVQAGQSKTSQTSERRRAPEEEELGFSLLRKISLHDGNVVFSPLGLAWAMAALTLGARGHSRAQLEE-PLLQPRLPALFKRLRDSLPELGLAQGSFAFIHKDFDIRETFLNLSKTYFDTECQAKRLMNHYMNQTQGKLPKLFDEINPDTELILVDYILFKGKWLIPFDPALTEMTFYLDKYKTVKVPMMYRSGKFASTFDTNFRCHVLKLPYRGNASMLVVLMGTLEDYLTTDLVWLRNMKARKMEVFFPKFKLDQKYKMHELLKQMGVQKIFSWSDLSNLANLKVSKILQRAMIEVDEEGTEAMAGTLSEITAYYMPPVIKVDRPFLFIVYEETSRTVLFLGRVVNPTLL >XP_043346178.1 protein Z-dependent protease inhibitor [Cervus canadensis] MWAVLSLLLACLLAQWLAPGSTLASRSPEVQAGQNKTNQTSERLWAPEEEELGFSLLRKISLHDGNVVFSPLGLAWAMAALTLGAGGHSRAQLEE-LLLQPRLPALFKQLRESLPELGLAQGSFAFIHKDFDIRETFLNLSKRYFDMECQAKSLMNHYMNQTQGKLPKLFDEINPDTELILVDYILFKGKWLIPFDPALTEMTFYLDKYKTVKVPMMYKSGKFASTFDKNFRCHVLKLPYRGNASMLVVLMGTLEDYLTTDLVWLRNMKARKMEVFFPKFKLDQKYKMHELLKQMGVRKIFSWADLSNLANLKVSKVLQRAMIEVDEEGTEAMAGTLSEITAYYMPPIIRVDRPFLFIVYEETSRTVLFLGRVVNPTLL >XP_043778021.1 protein Z-dependent protease inhibitor [Cervus elaphus] MWAVLSLLLACLLAQWLAPGSTLASRSPEVQAGQNKTNQTSERLWAPEEEELGFSLLRKISLHDGNVVFSPLGLAWAMAALTLGAGGHSRAQLEE-LLLQPRLPALFKQLRESLPELGLAQGSFAFIHKDFDIRETFLNLSKRYFDMECQAKSLMNHYMNQTQGKLPKLFDEINPDTELILVDYILFKGKWLIPFDPALTEMTFYLDKYKTVKVPMMYKSGKFASTFDKNFRCHVLKLPYRGNASMLVVLMGTLEDYLTTDLVWLRNMKARKMEVFFPKFKLDQKYKMHELLKQMGVRKIFSWADLSNLANLKVSKVLQRAMIEVDEEGTEAMAGTLSEITAYYMPPIIRVDRPFLFIVYEETSRTVLFLGRVVNPTLL >KAB0369185.1 hypothetical protein FD755_019190 [Muntiacus reevesi] MWAVLSLPLACLLAQWLAPGSTLASRSPEVQAGQNKTNQTSERLWAPEEEELGFSLLRKISLHDGNVVFSPLGLAWAMAALTLGARGHSRAQLEE-LLLQPRLPALFKRLRESLPELGLAQGSFAFIHKDFDIRETFLNLSKRYFDTECQAKRLMNHYMNQTQGKLPKLFDEINPDTELILVDYILFKGKWLIPFDPALTEMTFYLDKYKTVKVPMMYRSGKFASTFDTNFRCHVLKLPYRGNASMLVVLMGTLEDYLTTDLVWLRNMKARKMEVFFPKFKLDQRYKMHELLKQMGVRKIFSWSDLSNLANLKVSKILQRAMIEVDEEGTEAMAGTLSEITAYYMPPVIKVDRPFLFIVYEETSRTVLFLGRVVNPTLL >OCT68273.1 hypothetical protein XELAEV_18039571mg [Xenopus laevis] MKHRLCLLLPFLLTGLCFADHAIKQHKPSRKQRSEWNKQISAATVMDSMNTFGFNLYRKIANHDDNIFFSPFSVSLGLSSLLLGTRGNTYDQLLHGLNYNYLLPELLKTIKEKIEELVLNIGSLSFLHETFSMKEEFINLTKTYFDMEYKAKNEINAHVELTKGLISNFYDFLDPQTKLLLLDYIFFKGKWQYPFNPALTEETFFIDKYNSVTVPMMYKSDKVASLLDKDLSCTVFKLPYRGNAHMLIIKPEILEDHLTKELIWLAKMQSRKTDIFFPKFKLDQKYKLKSSLNELGIKELFTRANLTDLTNLLLTEVTQQAIIDVNERGTEAAAAAGAEIIAYSLPLTIRVNRPFLFLIYEEAFQSLLFIGRVTNPTKL >XP_004082346.1 protein Z-dependent protease inhibitor isoform X1 [Oryzias latipes] IKMLVVFALTCMCF-------------------------------------FAMNLYRKIANHDKNIFFSPLSVSTSFAALLMASDGITHQEILKVCNLEQLIPRLFQDLQENIGSLQLEQSMALFIRQRFEVEKTFQDNLKNFFQADIDSIKTINDYVRKTADKVPEMISTLNAMTKLLLINTIFFQGVWQIPFNPNFTENPFHIDNYNIVQVPMMFVEDKFYTMEDEPLGARVLKLPYKEGVSMLILLPNTIDNEITAQRFWIRNLEPMKLEVNMPKFKMERAYSLHNILPEMGMSSLFTFANLTRLSALRVSEVLHKAVIEVDEVGTTAAAATATGIIPYALPRRFTINRPFFFFIYHEETNALLFMGRVINPTKN >XP_015825579.1 PREDICTED: protein Z-dependent protease inhibitor-like [Nothobranchius furzeri] IKMAFLVVLACLCF-------------------------------------FAMNLYRKLANNDKNIFFSPLSVSTTFASLLMASGGITREEILRGLDLNEHIPKLFQLLQENIGSLKLEQSMALFISQQFEVKKTFEDRLKTFFQADIKSITLINEYIKKTGGKIVKMISTLDETTRLLLINSIYFQGAWKNPFNPNLTESAFHIDNYNVVQVSMMMKEARFFVTEDVLLGARVLKLPYQDGVSMLILLPNSIDEEISAEKFWIEGLRKTKLEVHVPKFKMEQAYALQNILPDMGMTSLFSSANLTGIGDLMVSEVLHKAVIEVDETGTTAAAATTVGITPYSLPRMFIVDRPFFFFIYHEETKSLLFMGRVIDPTKN >XP_030247366.1 protein Z-dependent protease inhibitor-like isoform X2 [Sparus aurata] MKMGFIPIVTFMCF-------------------------------------FAMELYRKISSHDKNIFFSPLSISTSFAALLMASDGVTRDEMLRGLNLEELIPKLFQLLNENIGSLKLDQGMALFMAPQFEVQNMFEDQIKEFFSADIGAIRFINEYVKRTHDKVTEMISSLDSATKLMLINTIFFQGAWQMPFNPNFTESPFYIDNYSVVQVPMMFMEDKFYMMEDISLGAKGLKLPYQEGVSMLILLPKVIDEEITAEKFCIKKLQKIKLEVHIPKFKMEQSYSLHNLLPEMGMASVFSSANLTKLSRLKVSEVLHKAVIEVDETGTTAAAATTIGITPFSLPRTFTVNKPFFFFIYHEDTNCVLFMGRVIDPTKN >XP_038050239.1 leukocyte elastase inhibitor-like [Patiria miniata] AVIQIISILTVIAL-------------------------------------FAFHLYQTLADHRDNIFFSPMSISIALAMTSLGARGNTARQIKDVLKFSSRLHSSFAELNSAIDKYVLRKANRLFGHKGFDLRQEFLADAERYYSSHMVAREFINSWVGETEDKIRDLLPHITGMTQLVLVNAIYFKADWVRQFDKSKTFDDFHVSKDQVLEVPMMHRKSKFNFAEDITLRCKLIELPYVGDFSMIVVLPDRLQKHLTNEKLLLNNLSNVTVGVAIPKFKLEETLHMNDVLYSMGMRDLFVKADLSGITDLFVSSVIHRAFLEVNEEGSEAAAATAVTINKRSIAPEFIADHPFLFFIADSKTKAIVFMGHCRKPEGV >XP_031557330.1 leukocyte elastase inhibitor-like [Actinia tenebrosa] FRLHSVLILA-VSL-------------------------------------FSLHLHQVLRGAEQNLFYSPSSILVALAMTHLGARGNTAKQMSSSFHLDKQLNAEFQKFLQKLKGNEIAMANRLFVQMGFEVSKQFQEDSEKFFNAEAGARQEVNQWVEKTKNKIKDLIPEFGPDTRLTLVNAIYFKGSWMSKFDSNNTQTPFQLTPSKTVQVPMMYKSDKFKYFENEGLKCKMLELPYSDKISMIILLPDKLEDSLNYSKLAIGHLKKEEVEVTLPKFKLSEKFSLKEVLSKMGASDLFNKADLTGINQLYVSEVVHKAFVDVNEEGTEAAAATAVRVALMCMNPIFFANHPFLFLIRHNESGAILFIGRLANPK-- >XP_039269246.1 serpin B9-like [Styela clava] ISLGIAICLAVMSK-------------------------------------FAYEMYKVAAKPNQNIFLAPTTVGSGLSMMLPGARESTKDQMLEGLMFKNDIECLMKMYSNELDTLQLRTANRLFGEKSFNFSSKFIEQTAK-YGVEMESRNFINQWVEATEGKIKDLFSGIRPDTVLAVVSAIYFKGLWKYPFDPLNTFKDFKVNDNKTVKADFMTKMINYRMTYSEDLEAQILDVPYDGNASMILIVPTRVEEMLSEKTMILDELQTQRVRLLLPKFKMSKTYQLKPILRRLGIKNLFNRANLSGMINLYVSTAVHKTFIKVDEKGTEAAGASGFGIVPLSLPPRLFCNRPFLFMIYEKNTDGVLFIGKVNDPTVQ >XP_030838146.1 leukocyte elastase inhibitor A isoform X3 [Strongylocentrotus purpuratus] FHITMVTLLT-LGM-------------------------------------FALHLYSATRAPDQNLFFSPLSVSTALGMTHLGARGTSSAQMSEVLRFNEHLHASFKQLNALLNKYTLKSANKLFGKAGADFLQEFLDNTGNFYNSAFEARTMINDWVAETEDKIQNLFPDLNSLTQLVLVNAIYFKSNWVKSFNRDDTEPVFRM-KDETAHLPMMFKDGEVMMTDDKERKCFVLEMPYDGDLSMLAILPWNVEEQLSMEVLWDSDLEPENAMYWVPRFKLEDTFSLSSILQSMGMADAFDKADFSGMTSLHISEVIHKAFVEVNEEGTEAAAATGVTMTKRSIRYRLRFDHPFLFLIRDRRTKAVLFLGRLVDPPHD >NP_524953.1 serpin 55B [Drosophila melanogaster] FDFNL----------------------------------------------FTSELFQLLSALKENVVFSPFSIQTCIALAFAGSQGETADEIAKALHFVPEVAQTFQFVLEKYNSNLLRVANKLYVQEGKQLKPAYQSAIKEQYHSEAAAAQAINAWVNKTQGKITELVSAFSDNTRLVLLNALHFKGSWAHKFSEERTEEIFWVGEEEQVKINYMNQKAKFNYGFFEDLGCTALEMPYQDDLSMFVLLPQALAEKLKTVNLLADKLTVEEVHVKFPKFKVDYSLELAEKLKQLGITKMFTQAEFSNLLGVFVSKVLHKATIEVNEEGTEAAAATGMIMMTRMMPLQFQADRPFLYVIWNKKN--ILFAGAFVKAA-- >XP_016773435.2 serine protease inhibitor 27A isoform X2 [Apis mellifera] LIVTYIIILTLKQC-----KSEIMNNKSQS---------------------FDWTFFKSISKYSKNVIISPISLKIALVLLYEGAQGETAYELANILQLPNATRKKFSNILQSLTAYTLNIGTRIYIDSNILVRQQYEANVKFFYNTDVPLVKAINNWVNITNANIDRIIEDSVKNSLMLIVNTLFFKGLWRGKFSPENTRNKFYLIDNRTVDTSIMHAYGRFYYVESSDLDAKILRIPYDGQFAIYLLLPRELIDKINPFVLYMWLMQDLSVDVLIPKFKFDFSSHLESILRELGICDIFDTATLTGIARLKVSNILQKAGIEINENGTTAYVATEIEIGNKNQDETFHANHPFLFYIEDESIGTIIYIGKIMNPLDT >AAS13528.1 serine or cysteine protease inhibitor [Caenorhabditis elegans] ---------------------------------------------------FALKLLATL--HSGSVVLSPLSISLGLALIHAGACGSTQKELEDVLGGS--IFEEFSGLMEAVNGVETKIVNRVFVNQAYTIHQDYLETVEKLYKASGQAAKTMNTFVEHTNGKIKDLIPASANNAFAFLVNAMYFKADWQSKFAKESTTGEFFTSEAESRQIPFLTDVDEHR-DYTEDVLFQVLSLKYADKFTLAIFLPKDALEKINGEYILLNDLKSSYVSVQIPKFKIEKELDLKETLEAIGIKEIFAGADLSGIAKVFISSGIHKAIIEVDEDGTTAAAASAFKVQLEMMPTQFVADHPFLFAVLFENH--TLFLG--------
PhyML tree of selected proteins (((((XP_039269246_1_serpin_B9_like__Styela_clava_:0.96906007,((XP_030838146_1_leukocyte_elastase_inhibitor_A_isoform_X3__Strongylocentrotus_purpuratus_:0.61745279,XP_038050239_1_leukocyte_elastase_inhibitor_like__Patiria_miniata_:0.54993682):0.148073,(XP_031557330_1_leukocyte_elastase_inhibitor_like__Actinia_tenebrosa_:0.57378038,(NP_524953_1_serpin_55B__Drosophila_melanogaster_:1.00650503,(XP_016773435_2_serine_protease_inhibitor_27A_isoform_X2__Apis_mellifera_:1.43574303,AAS13528_1_serine_or_cysteine_protease_inhibitor__Caenorhabditis_elegans_:1.06690442):0.09437447):0.31479898):0.15166458):0.25559743):0.31546253,(tr_Q5RIH8_Q5RIH8_DANRE_Serpin_peptidase_inhibitor__clade_A__alpha_1_antiproteinase__antitrypsin___member_10a_OS_Danio_rerio_OX_7955_GN_serpina10a_PE_3_SV_1:0.908696,(XP_015825579_1_PREDICTED__protein_Z_dependent_protease_inhibitor_like__Nothobranchius_furzeri_:0.18157902,(XP_004082346_1_protein_Z_dependent_protease_inhibitor_isoform_X1__Oryzias_latipes_:0.21809159,XP_030247366_1_protein_Z_dependent_protease_inhibitor_like_isoform_X2__Sparus_aurata_:0.19493596):0.06191075):0.32195595):0.31443597):0.36947189,(((NP_001092467_1_protein_Z_dependent_protease_inhibitor_precursor__Bos_taurus_:0.04019412,(XP_005695405_1_PREDICTED__protein_Z_dependent_protease_inhibitor__Capra_hircus_:0.011198,XP_027813160_1_protein_Z_dependent_protease_inhibitor_isoform_X1__Ovis_aries_:0.00538044):0.03090947):0.01728342,((XP_020754828_1_protein_Z_dependent_protease_inhibitor__Odocoileus_virginianus_texanus_:0.01786617,(KAF4018099_1_hypothetical_protein_G4228_009825__Cervus_hanglu_yarkandensis_:0.0027282,(XP_043346178_1_protein_Z_dependent_protease_inhibitor__Cervus_canadensis_:0.00000001,XP_043778021_1_protein_Z_dependent_protease_inhibitor__Cervus_elaphus_:0.00000001):0.00546282):0.00700384):0.00388133,(KAB0352921_1_hypothetical_protein_FD754_017778__Muntiacus_muntjak_:0.02225404,KAB0369185_1_hypothetical_protein_FD755_019190__Muntiacus_reevesi_:0.00263289):0.0141339):0.02472374):0.14298618,((NP_598301_2_protein_Z_dependent_protease_inhibitor_precursor__Rattus_norvegicus_:0.04945423,NP_659083_2_protein_Z_dependent_protease_inhibitor_isoform_1_precursor__Mus_musculus_:0.07088508):0.15452231,((NP_001125107_1_protein_Z_dependent_protease_inhibitor_precursor__Pongo_abelii_:0.02777384,sp_Q9UK55_ZPI_HUMAN_Protein_Z_dependent_protease_inhibitor_OS_Homo_sapiens_OX_9606_GN_SERPINA10_PE_1_SV_1:0.00266603):0.00000001,((XP_024204665_1_protein_Z_dependent_protease_inhibitor_isoform_X1__Pan_troglodytes_:0.00000001,XP_008956493_1_protein_Z_dependent_protease_inhibitor_isoform_X1__Pan_paniscus_:0.00000001):0.00270154,XP_004055674_1_protein_Z_dependent_protease_inhibitor_isoform_X1__Gorilla_gorilla_gorilla_:0.01099742):0.00555159):0.10628673):0.09204138):0.36018497):0.08619281,((XP_005506179_1_protein_Z_dependent_protease_inhibitor_isoform_X1__Columba_livia_:0.07008312,(XP_015143253_1_protein_Z_dependent_protease_inhibitor__Gallus_gallus_:0.02909761,XP_010710160_1_protein_Z_dependent_protease_inhibitor__Meleagris_gallopavo_:0.01646495):0.11419911):0.14677435,(XP_006266325_1_PREDICTED__protein_Z_dependent_protease_inhibitor__Alligator_mississippiensis_:0.00703628,XP_006025546_1_protein_Z_dependent_protease_inhibitor__Alligator_sinensis_:0.00071463):0.19471156):0.14857046):0.28349765,XP_040188191_1_protein_Z_dependent_protease_inhibitor__Rana_temporaria_:0.48596083,OCT68273_1_hypothetical_protein_XELAEV_18039571mg__Xenopus_laevis_:0.30291797);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)