PB0198
DATABASE


Click here to access PB0198 phyletic profile

PBID Uniprot Name Gene Alternative Organism Uniprot Description
PB0198 P07585 Decorin DCN CSCD, DSPG2, PG40, PGII, PGS2, SLRR1B Homo_sapiens May affect the rate of fibrils formation.

DomainsGene Ontology
PF01462 (LRRNT)
PF13855 (3_LRR_8)
GO:0010596 (acts upstream of or within) negative regulation of endothelial cell migration
GO:0014068 (acts upstream of or within) positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016239 (acts upstream of or within) positive regulation of macroautophagy
GO:0016525 (acts upstream of or within) negative regulation of angiogenesis
GO:0045944 (acts upstream of or within) positive regulation of transcription by RNA polymerase II
GO:0051901 (acts upstream of or within) positive regulation of mitochondrial depolarization
GO:0090141 (acts upstream of or within) positive regulation of mitochondrial fission
GO:1900747 (acts upstream of or within) negative regulation of vascular endothelial growth factor signaling pathway
GO:0003723 (enables) RNA binding
GO:0005515 (enables) protein binding
GO:0005518 (enables) collagen binding
GO:0005539 (enables) glycosaminoglycan binding
GO:0030021 (enables) extracellular matrix structural constituent conferring compression resistance
GO:0050840 (enables) extracellular matrix binding
GO:0009887 (involved in) animal organ morphogenesis
GO:0010508 (involved in) positive regulation of autophagy
GO:0019800 (involved in) peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan
GO:0005576 (located in) extracellular region
GO:0005615 (located in) extracellular space
GO:0005796 (located in) Golgi lumen
GO:0043202 (located in) lysosomal lumen
GO:0062023 (part of) collagen-containing extracellular matrix

External Links Description
Intact Open source database system and analysis tools for molecular interaction data.
Protein Atlas An open access resource for human proteins
InterPro (new pfam) InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish)

Selected proteins from model organisms

Mafft alignment of selected proteins

BMGE Cleaned alignment of selected proteins

PhyML tree of selected proteins

BLAST to find more sequences


Created by Puigbo and Nakamura @ University of Turku (2022)