PB0194

DATABASE

Click here to access PB0194 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0194	O95460	Matrilin-4	MATN4		Homo_sapiens	Major component of the extracellular matrix of cartilage.

Domains	Gene Ontology
PF00092 (2_VWA) PF10393 (Matrilin_ccoil) PF12662 (cEGF)	GO:0005509 (enables) calcium ion binding GO:0005515 (enables) protein binding GO:0030198 (involved in) extracellular matrix organization GO:0062023 (is active in) collagen-containing extracellular matrix GO:0005576 (located in) extracellular region

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|O95460|MATN4_HUMAN Matrilin-4 OS=Homo sapiens OX=9606 GN=MATN4 PE=1 SV=3 MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCGKDQCAEGGHGCQHQCVNAWAMFHCT CNPGYKLAADNKSCLAIDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDY CSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSY RCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSP EGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEA QGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEP AELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESL TLNLAQLTARLEDLENQLANQK >sp|O95460-2|MATN4_HUMAN Isoform 2 of Matrilin-4 OS=Homo sapiens OX=9606 GN=MATN4 MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCAIDLCAEGTHGCEHHCVNSPGSYFCH CQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDL CNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQN FELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMER GTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMY AVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPC ECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK >sp|O95460-3|MATN4_HUMAN Isoform 3 of Matrilin-4 OS=Homo sapiens OX=9606 GN=MATN4 MRGLLCWPVLLLLLQPWETQLQLTGKDQCAEGGHGCQHQCVNAWAMFHCTCNPGYKLAAD NKSCLAIDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQH ECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQL QADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQF SSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNV PRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPD FGTMTHLLENLRGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLTAR LEDLENQLANQK >sp|O95460-4|MATN4_HUMAN Isoform 4 of Matrilin-4 OS=Homo sapiens OX=9606 GN=MATN4 MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCAIDYCSFGNHSCQHECVSTPGGPRCH CREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCRE GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR YGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRS QDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLR GSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK >tr|Q5NJJ5|Q5NJJ5_DANRE Matrilin-4 OS=Danio rerio OX=7955 GN=matn4 PE=1 SV=1 MTRVLVYVSVLLAVMAATEARPKSGEPKCKSGPVDLVFIIDGSRSVRPHEFETMRKFMID IIHELDIGLAATRIGVVQYSSQVQNVFSLKAFSKTEQMVKAINEIIPLAQGTMTGLAIRY AMNVAFSAEEGARPNVPHVAVIVTDGRPQDRVAEVAAAARESGIEIYAVGVARADMTSLR AMASPPFEDHVFLVESFDLIHQFGLQFQDKLCGMDLCLESDHGCEHICESSPGSYQCLCL PGYTLNEDGKTCTPIDLCAEGKHDCEQICIASPGSFTCDCNTGYTLNDDKKTCKMIDYCS FGNDSCEHKCVSVLNGFNCRCDEGYSLNEDLKTCTMIDYCSFGNDSCEHECVSVLQSFYC QCRDGYTLNEDETTCTMIDYCSFGNDSCEHECVSVLNGFHCRCNEGYSLNDDLKTCTMID YCSFGNDSCEHECVSVLKGFHCRCNDGYTLNDDKKTCTMIDYCSFGNDSCEHECVSVLKG FHCICNEGYSLNDDKKTCTMIDYCSFGNDSCEHECVSVLKGFHCICNDGYSLNDDKKTCT MIDYCSFGNDSCEHQCVSVLKGFNCRCNEGYSLNGDLKTCTMIDYCSFGNDSCEHECVSV LNGFHCRCKDGYTLNEDKKTCTMIDYCSFGNHSCDHHCVSVLNGFFCRCNEGYTLQEDGK TCQSDNLCNTVEHGCEYQCVSTPGSYHCICPEGHVLQDDGKSCGTCRTSNIDLVLLIDGS KSVRPQNFELVKQFVNQVVDQLDVSAKGTRVGLVQYSSRVRTEFPLSMYHSKDEIKKAVM NVEYMEKGTMTGLALKHMVENSFSEAEGARPAEKNIPRVGLVFTDGRSQDDIQEWAKKAK EAGITMYAVGVGKAVEDELREIASDPVEKHFFYSADFTAISQIAENLKLNVCAAESKGDI EVKDPCACESLVEFQQVTMSTIEQLNQKLSAMTKRLEVLEKQLL
Selected proteins from model organisms >sp|O95460|MATN4_HUMAN Matrilin-4 OS=Homo sapiens OX=9606 GN=MATN4 PE=1 SV=3 MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCGKDQCAEGGHGCQHQCVNAWAMFHCT CNPGYKLAADNKSCLAIDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDY CSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSY RCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSP EGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEA QGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEP AELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESL TLNLAQLTARLEDLENQLANQK >sp|O95460-2|MATN4_HUMAN Isoform 2 of Matrilin-4 OS=Homo sapiens OX=9606 GN=MATN4 MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCAIDLCAEGTHGCEHHCVNSPGSYFCH CQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDL CNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQN FELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMER GTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMY AVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPC ECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK >sp|O95460-3|MATN4_HUMAN Isoform 3 of Matrilin-4 OS=Homo sapiens OX=9606 GN=MATN4 MRGLLCWPVLLLLLQPWETQLQLTGKDQCAEGGHGCQHQCVNAWAMFHCTCNPGYKLAAD NKSCLAIDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQH ECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQL QADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQF SSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNV PRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPD FGTMTHLLENLRGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLTAR LEDLENQLANQK >sp|O95460-4|MATN4_HUMAN Isoform 4 of Matrilin-4 OS=Homo sapiens OX=9606 GN=MATN4 MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGL LRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYA MNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGS LRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCAIDYCSFGNHSCQHECVSTPGGPRCH CREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCRE GHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGR YGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRS QDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEPAELHVSYAPDFGTMTHLLENLR GSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTLNLAQLTARLEDLENQLANQK >tr|Q5NJJ5|Q5NJJ5_DANRE Matrilin-4 OS=Danio rerio OX=7955 GN=matn4 PE=1 SV=1 MTRVLVYVSVLLAVMAATEARPKSGEPKCKSGPVDLVFIIDGSRSVRPHEFETMRKFMID IIHELDIGLAATRIGVVQYSSQVQNVFSLKAFSKTEQMVKAINEIIPLAQGTMTGLAIRY AMNVAFSAEEGARPNVPHVAVIVTDGRPQDRVAEVAAAARESGIEIYAVGVARADMTSLR AMASPPFEDHVFLVESFDLIHQFGLQFQDKLCGMDLCLESDHGCEHICESSPGSYQCLCL PGYTLNEDGKTCTPIDLCAEGKHDCEQICIASPGSFTCDCNTGYTLNDDKKTCKMIDYCS FGNDSCEHKCVSVLNGFNCRCDEGYSLNEDLKTCTMIDYCSFGNDSCEHECVSVLQSFYC QCRDGYTLNEDETTCTMIDYCSFGNDSCEHECVSVLNGFHCRCNEGYSLNDDLKTCTMID YCSFGNDSCEHECVSVLKGFHCRCNDGYTLNDDKKTCTMIDYCSFGNDSCEHECVSVLKG FHCICNEGYSLNDDKKTCTMIDYCSFGNDSCEHECVSVLKGFHCICNDGYSLNDDKKTCT MIDYCSFGNDSCEHQCVSVLKGFNCRCNEGYSLNGDLKTCTMIDYCSFGNDSCEHECVSV LNGFHCRCKDGYTLNEDKKTCTMIDYCSFGNHSCDHHCVSVLNGFFCRCNEGYTLQEDGK TCQSDNLCNTVEHGCEYQCVSTPGSYHCICPEGHVLQDDGKSCGTCRTSNIDLVLLIDGS KSVRPQNFELVKQFVNQVVDQLDVSAKGTRVGLVQYSSRVRTEFPLSMYHSKDEIKKAVM NVEYMEKGTMTGLALKHMVENSFSEAEGARPAEKNIPRVGLVFTDGRSQDDIQEWAKKAK EAGITMYAVGVGKAVEDELREIASDPVEKHFFYSADFTAISQIAENLKLNVCAAESKGDI EVKDPCACESLVEFQQVTMSTIEQLNQKLSAMTKRLEVLEKQLL >NP_038620.2 matrilin-4 precursor [Mus musculus] MRGPCCWPLSLLLLFLQSWETQLQSAGPRCYNGPLDLVFMIDSSRSVRPFEFETMRQFLVGLLRSLDVGL NATRVGVIQYSSQVQSVFPLGAFSRREDMERAIRAVVPLAQGTMTGLAIQYAMNVAFSEAEGARPSEERV PRVLVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRTMASPPLDQHVFLVESFDLIQEFGLQ FQGRLCGKDLCAELVHGCQHLCVNAPGTFYCACNSGYKLAPDNKNCLALDLCAEGTHGCEHLCVNSVDSY FCRCRAGFALQQDQRSCRAIDYCSFGNHSCQHECVSTLEGPQCRCREGHDLLPDGRSCRVRDFCNDVDHG CEFQCVSEGLSFHCLCPEGRRLQADGKSCDRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDV SPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRDL NVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEEELREIASEPSELHVSYSPDFSTMTHLL ENLKGSICPEEGIGAGTELRSPCECESLVEFQGRTLGALESLTQNLARLTERLEELENQLASRK >NP_001100009.1 matrilin-4 precursor [Rattus norvegicus] MKGPFCWPLPLLLLFLQSWETQLQPAGPRCYTGPLDLVFMIDSSRSVRPFEFETMRQFLVGLLHSLDVGL NATRVGVIQYSSQVQSVFPLGAFSNREDMERAIRAVVPLAQGTMTGLAIQYAMNVAFSEAEGARPSEERV PRVLVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDQHVFLVESFDLIQEFGLQ FQGRLCGKDLCAELEHGCQHLCVNAPGTFYCACNSGYKLAPDNRNCLAIDLCAEGTHGCEHLCVSSVDSY FCRCRAGFALQQDQRSCRAIDYCSFGNHSCQHECVSTLVGPQCRCREGHDLLPDGRSCQVRDFCNGVDHG CEFQCVSEGLSFHCLCPEGRRLQADGKSCDRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDV SPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEVQGARPRDL NVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEEELREIASEPSELHVSYSPDFNTMTHLL ENLKGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLTQNLARLTERLEELENQLASRK >XP_425698.5 matrilin-4 [Gallus gallus] MKLLPLAALLLLILTALEARPKPAALKCRTGPLDIVFVIDSSRSVRPFEFETMRRFMIDIIGNLDVGPNA TRVGVIQYSSQVQNIFSLKTFFTRAEMERAINSIVPLAQGTMTGLAIQYAMNVAFTVQEGARPPHKKIPR IAIIVTDGRPQDRVSEVAAHARNAGIEIYAVGIQRADMNSLRAMASPPLEEHVFLVESFELIQQFGKQFQ DKLCGVDMCMERDHGCQHSCVSTPGSFYCECHPGYQLNVDGKTCSPIDACADGRHGCEHHCISARGTYSC RCRAGYYLNQDRRSCTMIDYCSFGNHSCQHDCVSIPAGHRCRCRDGFMLQHDGKSCRAIDLCNGVDHGCE FKCVSSEGSFHCVCPEGQQLQADGKTCSKCGAGHVDLVMVIDGSKSVRPQNFELVKQFVNRIVDLLEVSP DGTHVGLVQYSSRVRTEFPLNKYHSAEEIKAAVMKMEYMEKGTMTGLALKHMVEHSFSELEGARPLSHNV PRIGLVFTDGRSQDDISEWAQRAKESGIVMFAVGVGKAVEEELRAIASEPVEQHFSYSADFTTMTHLVEN FKLNICPEEGRGETEIRSPCECEALVQFQTNTVAILQSLTERIAQMTARLEALEKQIALKK >XP_009435567.1 matrilin-4 isoform X1 [Pan troglodytes] MRGLLCWLMLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLPGLNVGPNA TRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPR VAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQ SRLCAIDLCAEGTHGCEHHCVNSPGSYFCRCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRC HCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLV DGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMER GTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVVYAVGVGKAVEA ELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLT LNLAQLTARLEDLENQLANQK >XP_005635167.1 matrilin-4 isoform X1 [Canis lupus familiaris] MRPPPPLAPAAWQSPAWARCLRRYLVQLPGRLRPSAPLCGRASELSGRLSAMRGLLCWPLPVLLFLLQPW ETLSQFAGPRCRTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRGLDVGPNATRVGVIQYSSQVQSVFP LGAFSRREDMERAIRALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRIAVIVTDGRPQDRVAEV AAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFNLIQEFGQQFRGRLCGKDLCAEGRHGCQ HQCVSTPGTFRCACNPGYQLAEDNKSCLAIDLCTGGTHGCEHHCISSPGSYFCRCRAGFVLQQDQRSCRA IDHCGFGNHSCQHECVSTFGGPRCRCREGHDLLPDGRSCQARDLCNGVDHGCEFQCVSEGLSYRCLCPEG QQLQADGKSCNHGCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRT EFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDI SVWARRAKEEGIVMYAVGVGKAVEEELRQIASEPAELHVSYSPDFGTMTHLLENLRGSICPEEGIGAGTE LRNLCECESLVEFQGRTLGALEKLTQNLAQLTARLEDLENQLATQK >NP_001162037.1 matrilin-4 precursor [Pongo abelii] MRGLLCWPLLLLLLQPWETQLQLAGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNA TRVGVIQYSSQVQSVFPLRAFSRSEDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPR VAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQ SRLCAIDLCAEGTHGCEHHCVNSPGSYFCRCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPQC HCREGHDLQPDGRSCQVQDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLV DGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMER GTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEA ELREIASKPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLT LNLAQLTARLEDLENQLANQK >NP_001178240.2 matrilin-4 precursor [Bos taurus] MRGLLYSLLPLLLLLLQPWETQLQLAGPRCSSGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGP NATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRAVVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEAHV PRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLNEHVFLVESFDLIQEFGRQ FQGRLCTLDLCTEGDHGCEHQCVSMPGSYFCRCQAGFVLQQEQRSCRAIDHCSFGNHSCQHDCVSIYGGP QCRCREGYDLLPDGRSCQARDLCNGVDHGCEFQCVSEGFSYRCVCPEGRQLQADGKSCSRCREGHVDLVL LVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYM ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDNISVWAARAKEEGIVMYAVGVGKAV EEELREIASEPAELHVSYSPDFSTMTHLLENLKGSICPEEGIGAGTELRSPCECESLVEFQGRTLGALES FLNLPLAQLTARLEDLENQLATQK >XP_017206222.1 PREDICTED: matrilin-4 isoform X1 [Oryctolagus cuniculus] MRGLLCWPLLVLLLLAQPWEAQPQFTDLPDRPAGPKCHTGPLDLVFVIDSSRSVRPLEFETMRRFLVGLV RSLDVGPNATRVGVIQYSSQVQSVFPLGAFSRREDMERALRTLVPLAQGTMTGLAIQYAMNVAFSVAEGA RPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDL IQEFGRQFRGRLCGKAPCAEGRHGCQHQCVNTQGAVRCACNPGYKLAADNKSCLAIDPCAEGTHGCDHHC VSSPGSYFCRCQAGFVLLQDQRSCRAVDPCSLSNHSCQHECVSTLDGPHCRCPDGHDLQPDGRSCRIRDL CNSVDHGCEFQCVSEGLSYRCLCPEGRPLEADGKSCSRTSRAAGCREGHVDLVLLVDGSKSVRPQNFELV KRFVTQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAELKQAVLAVEYMERGTMTGLALRHMVEH SFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEEELREIASEPAELHV SYSPDFSTMTHLLENLKGSICPEEGVGAGTELRSPCDCDSLVEFQGRALGSLESLTHRLAQLTARLEDLE SLLAGQK >XP_020933255.1 matrilin-4 [Sus scrofa] MPRRLPTHSGSAERSRPASRCSPIPAPQFASAAPGVAGAGGAALAPPQPPEEGGSLPASGRGRGPRSFSP PASPRVKCGRRLRSLQLPGGPHLRQAARAVTWSNCPGGSARRLRSAAAPRSCPAGSGPDSSALCSPSAMR GLLGLLLPLLLLLLQPWETQLQFAGPRCRTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGPNA TRVGVIQYSSQVQSVFPLGAFSRREDMEGAIRALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPR VAVIVTDGRPQDRVAEVAAQARSRGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGQQFQ GRLCRKDLCAEGGHGCQHQCVSAPGTFHCACNPGYRLAADNKSCLAINLCAEETHGCEHHCVSSPGSYFC HCRAGFVLQQDQRSCRAIDYCGFGNHSCQHECVNTFGGPRCRCREGHDLLPDGRSCQARDLCNGVDHGCE FQCVSEGLSYRCLCPEGQQLLADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSP EGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNV PRVGLVFTDGRSQDDVSVWAARAKEEGIVMYAVGVGKAVEEELREIASEPAELHVSYSPDFSTMTHLLEN LKGSICPEEGIGAGTELRSPCECDSLVEFQGRTLGALESLSQNLAQLTARLEELENQLAAQK >XP_010720616.1 matrilin-4 [Meleagris gallopavo] MKLLPLAAFLLLVLTALEARPKPAALKCRTGPLDIVFVIDSSRSVRPFEFETMRRFMIDIIGNLDVGPNA TRVGVIQYSSQVQNIFSLKTFFTRAEMERAINSIVPLAQGTMTGLAIQYAMNVAFTVQEGARPPHKKIPR IAIIVTDGRPQDRVSEVAAHARNAGIEIYAVGIQRADMNSLRAMASPPLEEHVFLVESFELIQQFGKQFQ DKLCGVDMCMEQDHGCQHSCVSTPSSFYCECHPGYQLNVDGKTCSPIDACADGRHGCEHHCISTRGTYSC RCRAGYHLNQDKRSCTMIDYCSFGNHSCQHDCVSIPAGHRCRCRDGFMLQHDGKSCRAIDLCNGVDHGCE FKCVSSEGSFHCVCPEGQQLHADGKTCNKCGAGHVDLVMVIDGSKSVRPQNFELVKQFVNRIVDLLEVSP DGTRVGLVQYSSRVRTEFPLNKYHSAEEIKEAVMKMEYMEKGTMTGLALKHMVEHSFSELEGARPLSHNV PRIGLVFTDGRSQDDISEWAQRAKESGIVMFAVGVGKAVEEELRAIASEPVEQHFSYSADFTTMTNLVEN FKLNICPEEGRGETEIRSPCECEALVQFQTNTVAILQSLTERIAQMTARLEALEKQIALKK >XP_008949583.1 matrilin-4 isoform X1 [Pan paniscus] MRGLLCWLMLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLPGLNVGPNA TRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPR VAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQ SRLCAIDLCAEGTHGCEHHCVNSPGSYFCRCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRC HCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRCREGHVDLVLLV DGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMER GTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEA ELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLT LNLAQLTARLEDLENQLANQK >XP_023106971.1 matrilin-4 isoform X1 [Felis catus] MRGLLCSPRLMLLLLLQPWESQLQFAGPRCRTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRGLDVGP NATRVGVIQYSSQVQSVFRLGAFSRREDMERAIRALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARV PRIAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQ FQGRLCGKDLCVEGGHGCQHQCVSALGTFHCACNPGYQLAEDNKSCLAIDLCAEGTHGCEHHCISSPGSY SCRCRAGFVLQQDQRSCRAIDHCSFGNHSCQHECVSTFRGPRCHCREGHDLLPDGRSCQARDLCNGVDHG CEFQCVSEGLSYRCLCPEGQQLQADGKSCNRCREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDV SPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRAL NVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEEELRQIASEPAELHVSYSPDFGSMTHLL ENLRGSICPDSHSPDSLCPAGRGGHRRGYRASEPVRMRKPRGVPGSHAGGAREANAEPGPAGGAPGGSGE PVGQPEVRAAGGSEPGRDAALRTGSPVCRRGAGAGQHRGPGGLGWRGGGAGGLPALRSSWPRLDQKPDCG GRRRELAPHAVALCCAQFFVGFPFCFLFLKKKKKKKKNFFFFSTGSVCGSCSAARGRGGQTERAPEAPGR RLLGERRFVRGVGLGGRGPGAASPSLFIQPRTDGSLCALREGRGLDANPRGPNETAPLHTPPPAPEGPAL RSLVLRISWCPQIRLKSC >XP_014955384.2 matrilin-4 isoform X1 [Ovis aries] MRPPPPPAPAARPSPPRAHCPCRYLVQLPGRLRPSAPLCGRASELSGRLRLDTSVLCWLSAMRGLLYSML PLLLLLLQPWETQLQLAGPRCSTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGPNATRVGVIQ YSSQVQSVFPLRAFSRREDMERAIRALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTD GRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLNEHVFLVESFDLIQEFGRQFQGRLCRKD LCAQGGHGCQHQCVSALGTFHCACNPGYQLAADNKSCMAIDHCSFGNHSCQHDCVSTFGGPQCRCREGYD LLPDRRSCQARDLCNGVDHGCEFQCVSEGFSYHCVCPEGRQLQADGKSCSRCREGHVDLVLLVDGSKSVR PQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLA LRHMVEHSFSEAQGARPRELNVPRVGLVFTDGRSQDNISVWAARAKEEGIVMYAVGVGKAVEEELREIAS EPAELHVSYSPDFSTMTHLLENLKGSICPEEGIGAGTELRSPCECESLVEFQGRTLGTLESLSQKLAQLT ARLEDLENQLATQK >XP_018872360.1 matrilin-4 isoform X1 [Gorilla gorilla gorilla] MRGLLCWPVLLLLLQPWETQLQLTGPRCHTGPLDLVFVIDSSRSVRPFEFETVRQFLMGLLRGLNVGPNA TRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPR VAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQ SRLCAIDLCAEGTHGCEHHCVNSPGSYFCRCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRC HCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYHCLCPEGRQLQADGKSCNRCREGHVDLVLLV DGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMER GTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEA ELREIASEPAELHVSYAPDFGTMTHLLENLRGSICPEEGISAGTELRSPCECESLVEFQGRTLGALESLT LNLAQLTARLEDLENQLANQK >XP_023811128.1 matrilin-4 [Oryzias latipes] MRPLRASRVFVLLGLVVLTAARPRAGPDQKCKPGPLDLIFLIDSSRSVRPHEFETMRKFMIDILNSLEIG PDSTRVGVVQYSSQVRSEFSLKTHGDLESVVAGIRQIVPLAQGTMTGLAIRYMMNEAFTAEQGDRPKVPN VAVIVTDGRPQDRVAEVAAEARERGIEIFAVGVARADMTSLRAMASLPFEDHVFLEESFDLIHQFGLQFQ DAFCGLDLCKEMDHGCEHVCENSPGSFHCLCSEGYTLNEDGKTCTAIDLCAEGKHDCEQVCISSPGNFSC DCREGYRLQDDGRTCSMVEFCSFGNDSCDHHCVNMLNGFYCTCKEGHRLQADGKTCQAIDLCAEGKHDCQ QVCMNMGPAVFTCDCNEGYTLNEDERSCTPIDLCAEGKHDCEQVCISAPGVFTCDCRKGFRLNHDKKTCT NMEMCSSVQHGCEHQCVNTPGSYYCVCPEGQLLQDDGKSCGACTSANIDLVLLIDGSKSVRPQNFELVKK FVNQVVDSLDVSAHGTRVGLVQYSSRVRTEFPLNMYHTAEDIKAAVMKVEYMEKGTMTGLALKHMLENSF SEAEGARPAARSVPRVGLVFTDGRSQDDISEYAKKAKEAGITMYAVGVGKAVEDELREIASEPVEKHFYY TTDFNAISTIADNLKLNVCPEESQGEVEVKDPCACENLVEFQQNTGSSLEQLTQKLAAMNTRLVELENQL LSRK >XP_021143581.1 matrilin-4 [Columba livia] MQGKAMQCRAIPPSPGIVWSCRIMMKLLPVAPLLLLLLMTLEARPKPAALKCRTGPMDIVFVIDSSRSVR PFEFETMRQFMMDIIGSLDVGPNATRVGVIQYSSQVQNIFSLKTFFTRADMEKAINSIVPLAQGTMTGLA IQYAMNVAFTTQEGARPLHKKIPRIAIIVTDGRPQDRVTEVATQARNAGIEIYAVGIQRADMNSLRAMAS PPLEEHVFLVESFELIQQFGKQFQDKLCGVDMCVEREHGCQHSCISTPGSFYCECNPGYRLNMDGRTCSP IDACADGRHGCQHHCISARGSYSCRCRAGYYLNQDKRSCTMIDYCSFGNHSCQHECVSIPSGHYCRCRSG FTLQPDGRSCRATDLCNGVDHGCEFKCVSTDGSYHCVCPDGQQLQADGKACSKCGSGHVDLVMVIDGSKS VRPQNFELVKQFVNRIVDLLEVSPHGTRVGLVQYSSRVRTEFPLNKYHSADEIKKAVMEVEYMEKGTMTG LALKHMVEHSFSELEGARPLSHNVPRIGLVFTDGRSQDDISEWARRAKESGIVMFAVGVGKAVEEELRAI ASEPVEQHFSYSADFTTMTHLVENFKLNICPEESKGETEIRSPCECEALVQFQTNTVAILQSLTEKIAQM TARLEDLEKQIAKKK >XP_017913405.1 PREDICTED: matrilin-4 [Capra hircus] MRPPPPPAPAARPSPPRAHCPCRYLVQLPGRLRPSAPLCGRASELSGRLRLHTSVLCWLSAMRGLLYSML PLLLLLLQPWETQLQLAGPRCSTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGPNATRVGVIQ YSSQVQSVFPLRAFSRREDMERAIRALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTD GRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLNEHVFLVESFDLIQEFGRQFHGRLCRKD LCAQGGHGCQHQCVSALGTFHCACNPGYQLAADNKSCMAIDHCSFGNHSCQHDCVSTFGGPQCRCREGYD LLPDRRSCQARDLCNGVDHGCEFQCVSEGFSYHCVCPEGRQLQADGKSCSRCREGHVDLVLLVDGSKSVR PQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLA LRHMVEHSFSEAQGARPRELNVPRVGLVFTDGRSQDNISVWAARAKEEGIVMYAVGVGKAVEEELREIAS EPAELHVSYSPDFSTMTHLLENLKGSICPEEGIGAGTELRSPCECESLVEFQGRTLGTLESLSQKLAQLT ARLEDLENQLATQK >XP_043335876.1 matrilin-4 isoform X2 [Cervus canadensis] MRGLLYSLLPLLLLLLQPWETQLQFAGPRCSTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGPNATRVGVIQY SSQVQSVFPLRAFSRREDMERAIRALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVA AQARARGIEIYAVGVQRADVGSLRAMASPPLNEHVFLVESFDLIQEFGRQFQGRLCRKDLCAQGGHGCQHQCVSAPGTFH CACNPGYQLAADNKSCVALDLCTERDRGCGHHCVRIPGSYFCRCQAGFVLRQDQRSCRAIDHCSFGNHSCQHDCVSTFGG PQCRCREGYDLLPDGRSCQARDLCNGVDHGCEFQCVSEGFSYRCMCPEGRQLQADGKSCSRCREGHVDLVLLVDGSKSVR PQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFS EAQGARPRALNVPRVGLVFTDGRSQDNISVWAARAKEEGIVMYAVGVGKAVEEELREIASEPAELHVSYSPDFSTMTHLL ENLKGSICPEEGIGAGTELRSPCECESLVEFQGRTLGALESLSQKLAQLTARLEDLENQLATQK >XP_043740388.1 matrilin-4 isoform X2 [Cervus elaphus] MRGLLYSLLPLLLLLLQPWETQLQFAGPRCSTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGPNATRVGVIQY SSQVQSVFPLRAFSRREDMERAIRALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVA AQARARGIEIYAVGVQRADVGSLRAMASPPLNEHVFLVESFDLIQEFGRQFQGRLCRKDLCAQGAHGCQHQCVSAPGTFH CACNPGYQLAADNKSCVALDLCTERDRGCGHHCVRIPGSYFCRCRAGFVLRQDQRSCRAIDHCSFGNHSCQHDCVSTFGG PQCRCREGYDLLPDGRSCQARDLCNGVDHGCEFQCVSEGFSYRCMCPEGRQLQADGKSCSRCREGHVDLVLLVDGSKSVR PQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFS EAQGARPRALNVPRVGLVFTDGRSQDNISVWAARAKEEGIVMYAVGVGKAVEEELREIASEPAELHVSYSPDFSTMTHLL ENLKGSICPEEGIGAGTELRSPCECESLVEFQGRTLGALESLSQKLAQLTARLEDLENQLATQK >KAB0351307.1 hypothetical protein FD754_016164 [Muntiacus muntjak] MRGLLYSLLPLLLLLLQPWETQLQFAGPRCSTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGPNATRVGVIQY SSQVQSVFPLRAFSRREDMERAIRALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVA AQARARGIEIYAVGVQRADVGSLRAMASPPLNEHVFLVESFDLIQEFGRQFQGRLCRKDLCAQGGHGCQHQCVSAPGTFH CACNPGYQLAADNKSCVALDLCTERDRGCGHHCVSIPGSYFCRCRAGFVLRQDQRSCRAIDHCSFGNHSCQHDCVSTFGG PQCRCREGYDLLPDGRSCQARDLCNGVDHGCEFQCVSEGFSYRCMCPEGRQLQADGKSCSRCREGHVDLVLLVDGSKSVR PQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFS EAQGARPRALNVPRVGLVFTDGRSQDNISVWAARAKEEGIVMYAVGVGKAVEEELREIASEPAELHVSYSPDFSTMTHLL ENLKGSICPEEGIGAGTELRSPCECESLVEFQGRTLGALESLSQKHILWSPGVFLNLSLAQLTARLEDLENQLATQK >KAB0381538.1 hypothetical protein FD755_003455 [Muntiacus reevesi] MRGLLYSLLPLLLLLLQPWETQLQFAGPRCSTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGPNATRVGVIQY SSQVQSVFPLRAFSRREDMERAIRALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVA AQARARGIEIYAVGVQRADVGSLRAMASPPLNEHVFLVESFDLIQEFGRQFQGRLCRKDLCAQGGHGCQHQCVSAPGTFH CACNPGYQLAADNKSCVALDLCTERDRGCGHHCVSIPGSYFCRCRAGFVLRQDQRSCRAIDHCSFGNHSCQHDCVSTFGG PQCRCREGYDLLPDGRNCQARDLCNGVDHGCEFQCVSEGFSYRCMCPEGRQLQADGKSCSRCREGHVDLVLLVDGSKSVR PQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFS EAQGARPRALNVPRVGLVFTDGRSQDNISVWAARAKEEGIVMYAVGVGKAVEEELREIASEPAELHVSYSPDFSTMTHLL ENLKGSICPEEGIGAGTELRSPCECESLVEFQGRTLGALESLSQKHILWSPGVFLNLSLAQLTARLEDLENQLATQK >KAF4023671.1 hypothetical protein G4228_015599 [Cervus hanglu yarkandensis] MRGLLYSLLPLLLLLLQPWETQLQFAGPRCSTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGPNATRVGVIQY SSQVQSVFPLRAFSRREDMERAIRALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVA AQARARGIEIYAVGVQRADVGSLRAMASPPLNEHVFLVESFDLIQEFGRQFQGRLCRKDLCAQGGHGCQHQCVSAPGTFH CACNPGYQLAADNKSCVALDLCTERDRGCGHHCVRIPGSYFCRCRAGFVLRQDQRSCRAIDHCSFGNHSCQHDCVSTFGG PQCRCREGYDLLPDGRSCQARDLCNGVDHGCEFQCVSEGFSYRCMCPEGRQLQADGKSCSRCREGHVDLVLLVDGSKSVR PQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFS EAQGARPRALNVPRVGLVFTDGRSQDNISVWAARAKEEGIVMYAVGVGKAVEEELREIASEPAELHVSYSPDFSTMTHLL ENLKGSICPEEGIGAGTELRSPCECESLVEFQGRTLGALESLSQKHILWKGPPRAPEASLTSHWPS >XP_018093529.1 matrilin-4 isoform X2 [Xenopus laevis] MWCLRLQFQFQCGRGQHLPPRIKTCRAPLYSACKAGGEGDRTQSFSLSVCDSRVRVTGVSSPALGSTGLNWTQTGLEQSS GLKMKMFYISTLLLISFATLDARPQTSGLVQKCKSGPMDLVFIIDSSRSVRPFEFETMRKFMIDIINPLEVGLSNTRVGV VQYSSQVQNVFSLKTFSNKSDMEKAINEIIPLAQGTMTGLAIQYAMNVAFTEEEGARPLSKNIPRVAIIVTDGRPQDRVT EVAAQARDTGIEIYAVGVQRADVSSLRTMASHPLDDHVFHVESFDLIQHLSIQFQDKLSCVDMCTEMDHGCQHKCVNIPS SYYCECNEGYKLNADGKTCSLIDLCAQGNHGCEQICVSSPGSYSCACRAGYQLNEDKKTCSLIDLCSQGDHGCEQICVSS PGSYSCACRAGYQLNEDKKTCSMIDYCSYGNHSCQHECVSILNGYYCRCNEGYTLQADGKTCLADDMCNVVDHGCEFKCV STPGSYYCICPEGQELQADGKTCNKCSTGYVDLVLVIDGSKSVRPQNFELVKEFVINIVDSLAISAQGTHIGLVQYSSRV RTEFSLDQYKNAQDIKTAVKNVQYMEKGTMTGLALKHMVEQSFSEAEGARKNVPKIGLVFTDGRSQDDISEWAKKAKEAG ITMYAVGVGKAVEDELNEIASEPVNKHSFYTADFSTMNLIAEDLKLNICPEEIKGTTETKNPCDCEHLVSFQTSTITKLE SLSEQLAQLNARLDDLENELVSKK >XP_006016728.1 matrilin-4 isoform X1 [Alligator sinensis] MKLLLVAPLLLFALTMLEARPKPAALKCKTGPLDIVFVIDSSRSVRPFEFETMRRFMIDIIHNLDVGLNA TRVGVIQYSSQVQNVFSLKTYFKRADMEKAINSIVPLSQGTMTGLAIQYAMNVAFTTQEGARELHKKIPR VAVIVTDGRPQDRVTEVAAQARDAGIEIYAVGVQRADMNSLRAMASHPLEQHVFLVESFDLIQQFGKQFQ DKLCGVDMCTELDHGCQHTCVSVPGSFYCGCNPGYKLNADGKTCSAIDACADGKHGCEHQCVSARGSYTC RCRLGYSLNDDKKTCTAINYCNFGNHSCQHECVSLVNGYYCRCNDGFTLQADGRSCQATDLCNGVDHGCE FKCVSTSGSYHCICPEGQQLQTDGKTCNKCKAGHIDLVLVIDGSKSVRPQNFELVKQFVNQIVDFLDVSP HGTRVGLVQYSSRVRTEFPLNKYKTANDVKAAVMKVEYMEKGTMTGLALKHMIEHSFSEAEGARPLSQNI PRIGLVFTDGRSQDDISEWAMKAKESGIVMFAVGVGKAVEEELREIASEPVEQHFSYSADFSTMTHIVDN LKLNICPEEGKGETEIRSPCECEALVQFQSNTVAILESLTEKLAQMTARLEDLENQIAKKK >XP_006275851.1 PREDICTED: matrilin-4 [Alligator mississippiensis] MKLLLVAPLLLFALTMLEARPKPAALKCKTGPLDIVFVIDSSRSVRPFEFETMRRFMIDIIHNLDVGLNA TRVGVIQYSSQVQNVFSLKTYFKRADMEKAINSIVPLSQGTMTGLAIQYAMNVAFTTQEGARELHKKIPR VAVIVTDGRPQDRVTEVAAQARDAGIEIYAVGVQRADMNSLRAMASHPLEQHVFLVESFDLIQQFGKQFQ DKLCGVDMCTELDHGCQHICVSVPGSFYCGCNPGYKLNADGKTCSAIDACADGKHGCEHQCVSARGSYTC RCRLGYSLNDDKKTCTAINYCNFGNHSCQHECVSLVNGYYCRCNDGFTLQADGRSCQATDLCNGVDHGCE FKCVSTSGSYHCICPEGQQLQTDGKTCNKCKAGHIDLVLVIDGSKSVRPQNFELVKQFVNQIVDFLDVSP HGTRVGLVQYSSRVRTEFPLNKHKTANDVKAAVMKVEYMEKGTMTGLALKHMIEHSFSEAEGARPLSQNI PRIGLVFTDGRSQDDISEWARKAKESGIVMFAVGVGKAVEEELREIASEPVEQHFSYSADFSTMTHIVDN LKLNICPEEGKGETEIRSPCECEALVQFQSNTVAILESLTEKLAQMTARLEDLENQIAKKK >XP_015813978.1 PREDICTED: matrilin-4 isoform X1 [Nothobranchius furzeri] MKMRTLSVLVLLTLAVLTTARPKAGAEQKCKSGPVDLVFLIDSSRSVRPHEFETMRKFMIDILDTLDIGL DTTRVGVVQYSSQVRSEFSLKTHSKLENMVKAINEIIPLAQGTMTGLAIRYLMNEAFSPEQGDRPEVPNV AVIVTDGRPQDRVAEVAAEAREKGIEIFAVGVARADMTSLRAMASPPFEDHVFLVERFDLIYQFGLQFQN KLCGLDLCVESDHGCEHLCESSPGSYHCLCLPGYTLNDDGKTCTAIDLCAEGKHNCEQICISSPGSLTCD CNQGYHLNEDKKTCSAINLCAEGKHDCGQVCVNMGPAIFTCDCSEGYRLNEDEKTCSAIDVCAEGKHDCG QVCVNMGPGIFTCDCSEGYRLNEDEKTCSAIDLCAEGKHDCEQMCISTPGAFTCDCNKGFKLNDDKKTCT NMDMCNTVAHGCEHQCVNTPGSFHCICPEGQPLQDDGKSCGTCKSAVIDLVLLIDGSKSVRPQNFELVKK FVNQVVDTLDLSAHGTRVGLVQYSSRVRTEFPLNKYHTAEEIKAAVMKVEYMEKGTMTGLALKHMLENSF SEAEGARPASRNIPRVGLVFTDGRSQDDISEYAKKAKEAGITMYAVGVGKAVEEELREIASEPVEKHFYY TTDFSAISTIAENLKLNVCPAESQGEIEVKDPCACENLVEFQQATMSSLQQLTQKLTSMAARLEQLENQL LSRK >XP_020767141.1 matrilin-4 [Odocoileus virginianus texanus] MRRLLYSLLPLLLLLLQPWETQLQFAGPRCSTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGP NATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARV PRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVGVQRADVGSLRAMASPPLNEHVFLVESFDLIQEFGRQ FQGRLCPLDLCTKRDHSCGHHCISVPGSYFCQCQAGFVLQQDQRSCRAIDHCSFGNHSCQHDCVSTFGGP QCRCREGYDLLPDGRSCQARDLCNGVDHGCEFQCVSEGFSYRCMCPEGRQLQADGKSCSRCREGHVDLVL LVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYM ERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDNISVWAARAKEEGIVMYAVGVGKAV EEELREIASEPAELHVSYSPDFSTMTHLLENLKGSICPEEGIGAGTELRSPCECESLVEFQGRTLGALES LSQKLAQLTARLEDLENQLATQK >XP_030275675.1 matrilin-4 isoform X1 [Sparus aurata] MKMRQLRGFILLTLAVLAAARPKAGPEQKCKSGPVDLVFLIDSSRSVRPHEFETMRKFMIDILATLDIGL NATRVGVVQYSSQVRSEFSLKTHAKLETMVKGINEIIPLAQGTMTGLAIKYVMNNAFTAEAGDRPKVPNV VVIVTDGRPQDRVAEVAAEAREKGIEIYAVGVARADMTSLRAMASPPFEDHVFLVESFDLIHQFGLQFQD KLCGMDLCLESDHGCEHICESSPGSFHCLCLPGYTLNDDGKTCAAIDLCAEGKHDCEQICVSSPGSFTCD CNKGYKLNDDKKTCSMIDYCSFGNHSCDHECVSVLNGYHCRCNDGYRLLDDGKTCQAIDLCAEGKHDCEQ ICVSAPGVFTCDCNQGYTLNKDEKTCTPIDLCAEGKHDCEQICVSAPGVFTCDCNQGYTLNKDEKTCTPI DLCAEGKHDCEQICVSAPGVFTCDCNQGYTLNKDEKTCTPIDLCAEGKHDCEQICVSAPGVFTCDCNQGY TLNKDEKTCTPIDLCAEGKHDCEQICVSAPGVFTCDCNQGYTLNKDEKTCTPIDLCAEGKHDCEQICLSA PGVFTCDCNKGFKLNKDKKTCTNMDLCNTVEHGCEHQCVSTPGSYYCICPEGQLLQEDGKSCGTCKSANI DLVLLIDGSKSVRPQNFELVKKFVNQVVDSLDVSTHGTRVGLVQYSSRVRTEFPLNMYHTADEIKAAVMK VDYMEKGTMTGLALKHMVENSFSEAEGARPASRNIPRIGLVFTDGRSQDDITEFAKKAKEAGITMYAVGV GKAVEDELREIASEPVEKHFYYTTDFTAISTIAENLKLNVCPEESQGEIEVKDPCACESLVEFQQATMSS LEQLTQKLSGMTARLEQLENQLLSRK >XP_040187548.1 matrilin-4 isoform X1 [Rana temporaria] MKLLYISTLLLVLITQLKARPPAELQLCKTGPMDLIFIIDSSRSVRPFEFESMRKFMIDMINSLEIGPSH TRVGVVQYSSQVQNVFSLKTYTTKAQMHKAINDIIPLAQGTMTGLAIQYTMNVAFTEEEGARPLSQRIPR VAVIVTDGRPQDRVTEVAAQAREAQIEIYAVGVQRADVNSLRTMASPPIEDHVFYVESFDLIQHFAIQFQ DKLCGVDMCTEMDHGCQHTCVSVPSSYYCKCNPGYKLNADGKTCSIIDMCAQGDHGCEHLCVSSPGSYTC ACREGYRLNNDKKTCSPIDLCARGNHGCEQLCVSSPGSYTCACRTGYKLNNDKKTCSMIDLCAQGSHGCE QLCISSLGSYTCGCRTGFQLNNDKKTCSMIDYCSYSNHSCQHECVGILNGYYCRCNEGYTLQSDGKTCLA SDMCNVVDHGCEFKCVSTPGSYHCICPEGQELQADGKTCNKCSTGYIDLVFVIDGSKSVRPQNFELVKQF VIKIVDSLDVSPHGTHVGLVQYSSRVRTEFSLNQFKSSKDVSNAVRNIEYMEKGTMTGLSLKHMVEHSFS QQEGARPNVPKIGLVFTDGRSQDDISEWAKRAKDAGITMYAVGVGKAVEEELNEIASDPVNKHSFYTADF TTINLIAEDLKLNICPEEIKGETEIKNPCECEHLVNFQTNTLTTLGNLAEKLAQLTARLDILEHELKEKK >KAG6801720.1 fibrillin-2 isoform X1 [Apis mellifera caucasica] MKATSVKRVLGDCPLVQAPQWGRVRERVLKDGTLQTVYSCEPGRRLKGHKILTCTADGWNHPIPKCVPHDNRFRHFPTDV YLGDDPISAAGEERAARDRVRARKRIGELKKRRKAKERRQRMRHGGEKSAVEPPPPALPRAALNETIMSRLDLSCIMKAR RKGFTKAPPVENAYPAKYARRKSVLPPYNRYLVAVYECTEGYVFEDSTTDRLFCSDGAWLGTIPRCVKVEEATLNNVKRC NQDRGGCEHVCEDTQTGVNCSCFDGFRVKGSSCIDIDECAESTAGCAQICHNDPGSFHCECHSGYQLGTDGKSCLDVNEC LVNNGHGPCQGGCINLEGSYECNCSDIPGHKLAADNHTCEDIDECSTNNGGCSHVCLNTPGSAFCLCPDGFYLTNDWKTC QDVNECENASKVCTNNTDCENTVGSFKCVSKPQKMTKVLQDEDYDAEDDEDDDDYDEEEGITEIPEFGKCEDGFRKSKNG ECIDIDECSDEGELPSCQHGCVNEPGGYYCTCHLGFKLGEDGVSCQDIDECEDGSRPCSHGCNNTEGSFECTCPTGFTLK EDNLTCARARSCETLSTPCSHECRESEDGPICVCPLGYRVHEDEVSCVDTDECAVNPCSHSCVNFEGGFACTCPQGFQTL EHDKYNCTDVDECANNVHDCEHECVNVQGGYTCNCRSGFALNDDNRTCSDVDECLDGVHRCEQICVNSIGNYTCSCREGY RISKEGFLDCVDINECDEGGHGCSHECSNEEGGFKCGCPPGYLLGNDSRICQDANECLEGTHQCSHECVNLQGSYACTCP LGMTVSEDKRLCVPLDPCRFANCSHTCERRRDTFECGCPDGFVLHEDGRTCQDFDECLENEHDCSHECANTLGSYECLCP DGLTLLQDGLTCEDPSCPEGLRQDDEGGCRDIDECLERNHECSHICVNEHATYRCSCLSGWTLSDDGVTCVLSDPCANSS CSHICLSYASTPVCDCPPGYELAADAATCEDVDECRDGSANCSFSCTNTDGSYACDCPQGFILGEDGRSCVDVDECARRD HDCPRECVNLEGTYECVCPIGYAFSKTELACVDVDECGTGQHACSHACTNTPGGYNCTCPIGWRLREDSRNCFPSTVHRN CSHAYERDGEETRCGCPEGFELQDDEATCGDVDECAEHPPPCPYRCVNTKGSYRCECPPGLRLRQDRTTCQDIDECVENN NGGCSHDCANTQGSFHCVCPRGYELIEDGKTCADVDECAVNDNGGCSHDCTNTQGSFHCVCPRGYELIEDGKTCADVDEC IVNDNGCSHECANTEGSFYCICPRGYELIEDGKTCADVDECTRKDVHGCSHRCENLDGGYVCSCPDGWIVGRDNRTCTMA CEAAPHNCSHTCVNVRGGYECECPAGWELSSDGRTCEEVDFCAGGHGCSHECARVAGGGFQCRCPAGYVLSEDNRSCLDR NECEEGNGGCSHSCVNTDGSYECGCPNGYRLAADRNTCEDVNECIEDNGGCSHLCANIEGGVECACPDNYKLLEDDGKTC VEIDECLIDNGGCTHLCHYENGTVSCFCPPGMILADDNATCAEENKCYADNGGCSHYCSYEDGRVACSCPTDLVLSENGT VCVEENGCSSGNGGCSHDCRYEGGETFCLCPDDMILADDDKLRCVYANKCFVDNGGCSDICSFSNGSVACECPSGFKLSE GDNATCVDVDECSELLDNCTHRCTNTEGGFECGCNEGFKVSPVEPAFCDDVDECEDARGAGCSHACANLVGSFHCTCPTG YVLENDNKTCRLVDGCKRNNGNCSHHCHHVEEGGEVVHCSCPLGFRLKQDQRTCEDIDECEEFENDVDLGCSHICVNTEG GYYCECPSGYILLPENKKNCIDMNECLNDRHNCSHDCLNLLGSYVCTCYQGHYLHSDKSTCLDIDECLERNGGCSHQCTN TIGGHFCSCPTGYELSQDEKTCIDVDECKTDLADCPHECVNTLGSWTCTCPDGHALANDSKTCVDVDECKVDNGGCSHAC LNVVGGVRCNCPIGLRLDDDGKTCNDVDECSTDNGGCSDVCVNFVGSYSCRCVNAGLHLHTDAKTCLDVNECEMENGGCS DNCINVRGSYRCECPAGFRLKSDQRTCDDVNECDHDNGGCSHECVNELGGYRCDCPPGHELRNKSRCHPVDPCANDNGGC EQTCTARNGTVACGCKEGFRLDENEDPPRCRDIDECAGSQHGCDQLCVNTVGSFQCSCKQGFEMQNSTCVDIDECATMDC KGYECINSYGSYRCECDIGHRLEGDHCVDINECAWNNGGCEHDCINTVGSYVCACRPGYIPRRRNRNQCQDINECLNHNG GCNGGCVNTAGSYYCTCNGDLVLASDERTCISAESRCRAMEPPLHAEIRCPGHSSGAMDYPVGARCHIQCRRGFRLEGPH TRYCMAGDQWNGKEPICIQASIVTDSRYHSDMPRPFVRCPRDMDVELPARQNTIRVSFPQPKSNMNWWRYVDASPSWAKQ LQADLPAGTTVVTFTAWSPVSNYTSTCRIVIRVRDTENPKVSTCPTSFEVRLSPGERNRLIFWQEPTFTDNVGVERVYKT REPGQLMYPGIHNVRYIASDAAGNRAECHFSIHVRESEHRRDSEPRYYRRRMLMCPGRSPQPIPSTAYGWQIPSGCYLRY TRIFSGAYAVQNYRGQRQNGYQEARAAYHQVHPVHGGQGQTQLHSTSYPLGDLAETNNGGRNDAICGRSMHDSGKISIIC GSYEMVTFANPTGSIVISYTEDI >XP_039271077.1 tenascin-N-like [Styela clava] MEHRNPGRSNFYHRGLTFGIIIILAWMTPQTEAQKEECRQRPMDIVFVIDGSRSVRPWNFKTVQDAVKDMVDAFEKIGPE ETQIGLVQYSSRVRQEFKLNDYYSKEEVNEAIDGIKYMEMGTMTGRALKFITEYSFTAAYGARSDNPDVLKVAVVITDGR AQDNRTVHFWQKKAKDAGIILFAIGVGRRISDKDLLLIASEPKEKHQFYVKNFDLIGSLPVMLHEQICDVDECEQEIDNC QQTCKNTIGSFICGCEDGFVLQDDRASCLLYDPCFEADCGYKCEPAPAGGYRCTCPDGYKLDRDEKGCVAIAPSNLESLT LTDITHTTMRATWSLVSPELEDMIDHYLVRYKKAGDDGETVEVTVNERAIVLEGLEPGTEYLVSVTAYTADGLKSETIKA QNTTLFLGETTLDLFNPTLTTMQAKWEPAGGDLLSQYVLTITSPEQNRTFTITTDADTTEAPLLEGLEPGQLYEGVVTPM YGKLAGGPGRDTETTKSLIKPNIRVTDTTLSTVDVEFTGIGMPADRYELTLVDVETGETKYVEVDGSESTAKFYDCTPGK EYTVTVRGYITEGGREFESPEGVTEGKTKHIPAPVVDITSTGLATADVMWTISGYTPLLFKVSYCPKNDPENKKHIETED ISTKLTGLEPGIEYEVEVVAVDFDDDKKFTSEPGSDTDATKSLHAPPVMATGRTYTTATVKWGEIGMPANTWELRYHPVG SPDIVKTLVFDGSVNKTILEDLTHDTEYEVVVVGVVIEEGERFESPPGSDPFTLGALDPPVVTISDPTTSSLNSSWVDNS PTIPLTK
Mafft alignment of selected proteins >sp|O95460|MATN4_HUMAN Matrilin-4 OS=Homo sapiens OX=9606 GN=MATN4 PE=1 SV=3 ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MRGLLCW--PVLLLLLQPW- ETQLQL------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------T--GPRCHTGPLDLVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRQFLMGLLRGLN----VGPNATRVGVIQ--YSSQVQSVFPLRAFSRR-EDMERAI RDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQ- -ARARGIEIYAV--GV-QRADVGSLRAMASPPLD-EHVFLVESFDLIQEF---------- ------------------------------------------------------------ -----------------------GLQFQSRLC-------------GKDQCAEGGHGCQHQ CVNAWAMFHCTCNPGYKLAADNKSCLAIDLCAEGTHGCEH-------------------- ---------------------HCVNSPGS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YFCHCQVGF------------------ ------------------------------------------------------------ ----------------------------------------------VLQQDQRSCRAIDY CSFGNHSCQHECVSTPGG-PRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLS YRCLCPEGRQ-----------LQADGKSCNR------C---REGHVDLVL---------- -LVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF-PLGRYGTA AEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------DISVWA-------------------------------------- ---ARAKEEGIVMYAVGV------------------------------------------ --GKAVE-------------------AELREIASE------------------------- --PAEL----------------------------------HVSYAPDFGTMTHLLENLRG S------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------GISAGTE------------------------LRSP------------------ -----------CECESLVEF---------------------------------------- ------------------------------------------------------------ QGRTLGALES-LTLN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LAQLTARLEDLEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLANQK------------------------------------- ------------------- >sp|O95460-2|MATN4_HUMAN Isoform 2 of Matrilin-4 OS=Homo sapiens OX=9606 GN=MATN4 ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MRGLLCW--PVLLLLLQPW- ETQLQL------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------T--GPRCHTGPLDLVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRQFLMGLLRGLN----VGPNATRVGVIQ--YSSQVQSVFPLRAFSRR-EDMERAI RDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQ- -ARARGIEIYAV--GV-QRADVGSLRAMASPPLD-EHVFLVESFDLIQEF---------- ------------------------------------------------------------ -----------------------GLQFQSRLC---------------------------- --------------------------AIDLCAEGTHGCEH-------------------- ---------------------HCVNSPGS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YFCHCQVGF------------------ ------------------------------------------------------------ ----------------------------------------------VLQQDQRSCRAIDY CSFGNHSCQHECVSTPGG-PRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLS YRCLCPEGRQ-----------LQADGKSCNR------C---REGHVDLVL---------- -LVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF-PLGRYGTA AEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------DISVWA-------------------------------------- ---ARAKEEGIVMYAVGV------------------------------------------ --GKAVE-------------------AELREIASE------------------------- --PAEL----------------------------------HVSYAPDFGTMTHLLENLRG S------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------GISAGTE------------------------LRSP------------------ -----------CECESLVEF---------------------------------------- ------------------------------------------------------------ QGRTLGALES-LTLN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LAQLTARLEDLEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLANQK------------------------------------- ------------------- >sp|O95460-3|MATN4_HUMAN Isoform 3 of Matrilin-4 OS=Homo sapiens OX=9606 GN=MATN4 ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MRGLLCW--PVLLLLLQPW- ETQLQ------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------LT-------------GKDQCAEGGHGCQHQ CVNAWAMFHCTCNPGYKLAADNKSCLAIDLCAEGTHGCEH-------------------- ---------------------HCVNSPGS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YFCHCQVGF------------------ ------------------------------------------------------------ ----------------------------------------------VLQQDQRSCRAIDY CSFGNHSCQHECVSTPGG-PRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLS YRCLCPEGRQ-----------LQADGKSCNR------C---REGHVDLVL---------- -LVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF-PLGRYGTA AEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------DISVWA-------------------------------------- ---ARAKEEGIVMYAVGV------------------------------------------ --GKAVE-------------------AELREIASE------------------------- --PAEL----------------------------------HVSYAPDFGTMTHLLENLRG S------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------GISAGTE------------------------LRSP------------------ -----------CECESLVEF---------------------------------------- ------------------------------------------------------------ QGRTLGALES-LTLN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LAQLTARLEDLEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLANQK------------------------------------- ------------------- >sp|O95460-4|MATN4_HUMAN Isoform 4 of Matrilin-4 OS=Homo sapiens OX=9606 GN=MATN4 ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MRGLLCW--PVLLLLLQPW- ETQLQL------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------T--GPRCHTGPLDLVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRQFLMGLLRGLN----VGPNATRVGVIQ--YSSQVQSVFPLRAFSRR-EDMERAI RDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQ- -ARARGIEIYAV--GV-QRADVGSLRAMASPPLD-EHVFLVESFDLIQEF---------- ------------------------------------------------------------ -----------------------GLQFQSRLC---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------AIDY CSFGNHSCQHECVSTPGG-PRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLS YRCLCPEGRQ-----------LQADGKSCNR------C---REGHVDLVL---------- -LVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF-PLGRYGTA AEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------DISVWA-------------------------------------- ---ARAKEEGIVMYAVGV------------------------------------------ --GKAVE-------------------AELREIASE------------------------- --PAEL----------------------------------HVSYAPDFGTMTHLLENLRG S------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------GISAGTE------------------------LRSP------------------ -----------CECESLVEF---------------------------------------- ------------------------------------------------------------ QGRTLGALES-LTLN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LAQLTARLEDLEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLANQK------------------------------------- ------------------- >tr|Q5NJJ5|Q5NJJ5_DANRE Matrilin-4 OS=Danio rerio OX=7955 GN=matn4 PE=1 SV=1 ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MTR-VLVYVSVLLAVMAAT- EARPKS------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------G--EPKCKSGPVDLVFII---------------- ------------------------------------------------------------ -----------------DGSRSVR------------------------------------ ----------------------------------------------------------PH EFETMRKFMIDIIHELD----IGLAATRIGVVQ--YSSQVQNVFSLKAFSKT-EQMVKAI NEIIPLAQGTMTGLAIRYAMNVAFSAEEGARP---NVPHVAVIVTDGRPQDRVAEVAAA- -ARESGIEIYAV--GV-ARADMTSLRAMASPPFE-DHVFLVESFDLIHQF---------- ------------------------------------------------------------ -----------------------GLQFQDKLC-------------GMDLCLESDHGCEHI CESSPGSYQCLCLPGYTLNEDGKTCTPIDLCAEGKHDCEQICIASPGSFTCDCNTGYTLN DDKKTCKMIDYCSFGNDSCEHKCVSVLNGFNCRCDEGYSLNEDLKTCTMIDYCSFGNDSC EHECVSVLQSFYCQCRDGYTLNEDETTCTMIDYCSFGNDSCEHECVSVLNGFHCR----- --------------------------------CNEGYSLNDDLKTCTMIDYCSF------ ------------------------------------GNDSCEHECVSVLKGFHCRCNDGY TLNDDKKTCTMIDYCSFG-NDSCEHECVSVLKGFHCICNEGYSLNDDKKTCTMIDYCSFG NDSCEHECVSVLKGFHCICNDGYSLNDDKKTCTMIDYCSFGN-DSCEHQCVSVLKGFNCR CNEGYSLNGDLKTCTMIDYCSFGNDSCEHECVSVLNGFHCRCKDGYTLNEDKKTCTMIDY CSFGNHSCDHHCVSVLNG-FFCRCNEGYTLQEDGKTCQSDNLCNTVEHGCEYQCVSTPGS YHCICPEGHV-----------LQDDGKSCGT------C---RTSNIDLVL---------- -LIDGSKSVRPQNFELVKQFVNQVVDQLD-VSAKGTRVGLVQYSSRVRTEF-PLSMYHSK DEIKKAVMNVEYMEKGTMTGLALKHMVENSFSEAEGARPAEKNIPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------DIQEWA-------------------------------------- ---KKAKEAGITMYAVGV------------------------------------------ --GKAVE-------------------DELREIASD------------------------- --PVEK----------------------------------HFFYSADFTAISQIAENLKL N------------------------------------------VCAAE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------SKGDIE------------------------VKDP------------------ -----------CACESLVEF---------------------------------------- ------------------------------------------------------------ QQVTMSTIEQ-LNQK--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LSAMTKRLEVLEK-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLL---------------------------------------- ------------------- >NP_038620.2 matrilin-4 precursor [Mus musculus] ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MRGPCCWPLSLLLLFLQSW- ETQLQS------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------A--GPRCYNGPLDLVFMI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRQFLVGLLRSLD----VGLNATRVGVIQ--YSSQVQSVFPLGAFSRR-EDMERAI RAVVPLAQGTMTGLAIQYAMNVAFSEAEGARPSEERVPRVLVIVTDGRPQDRVAEVAAQ- -ARARGIEIYAV--GV-QRADVGSLRTMASPPLD-QHVFLVESFDLIQEF---------- ------------------------------------------------------------ -----------------------GLQFQGRLC-------------GKDLCAELVHGCQHL CVNAPGTFYCACNSGYKLAPDNKNCLALDLCAEGTHGCEH-------------------- ---------------------LCVNSVDS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YFCRCRAGF------------------ ------------------------------------------------------------ ----------------------------------------------ALQQDQRSCRAIDY CSFGNHSCQHECVSTLEG-PQCRCREGHDLLPDGRSCRVRDFCNDVDHGCEFQCVSEGLS FHCLCPEGRR-----------LQADGKSCDR------C---REGHVDLVL---------- -LVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF-PLGRYGTA AEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRDLNVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------DISVWA-------------------------------------- ---ARAKEEGIVMYAVGV------------------------------------------ --GKAVE-------------------EELREIASE------------------------- --PSEL----------------------------------HVSYSPDFSTMTHLLENLKG S------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------GIGAGTE------------------------LRSP------------------ -----------CECESLVEF---------------------------------------- ------------------------------------------------------------ QGRTLGALES-LTQN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LARLTERLEELEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLASRK------------------------------------- ------------------- >NP_001100009.1 matrilin-4 precursor [Rattus norvegicus] ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MKGPFCWPLPLLLLFLQSW- ETQLQP------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------A--GPRCYTGPLDLVFMI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRQFLVGLLHSLD----VGLNATRVGVIQ--YSSQVQSVFPLGAFSNR-EDMERAI RAVVPLAQGTMTGLAIQYAMNVAFSEAEGARPSEERVPRVLVIVTDGRPQDRVAEVAAQ- -ARARGIEIYAV--GV-QRADVGSLRAMASPPLD-QHVFLVESFDLIQEF---------- ------------------------------------------------------------ -----------------------GLQFQGRLC-------------GKDLCAELEHGCQHL CVNAPGTFYCACNSGYKLAPDNRNCLAIDLCAEGTHGCEH-------------------- ---------------------LCVSSVDS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YFCRCRAGF------------------ ------------------------------------------------------------ ----------------------------------------------ALQQDQRSCRAIDY CSFGNHSCQHECVSTLVG-PQCRCREGHDLLPDGRSCQVRDFCNGVDHGCEFQCVSEGLS FHCLCPEGRR-----------LQADGKSCDR------C---REGHVDLVL---------- -LVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF-PLGRYGTA AEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEVQGARPRDLNVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------DISVWA-------------------------------------- ---ARAKEEGIVMYAVGV------------------------------------------ --GKAVE-------------------EELREIASE------------------------- --PSEL----------------------------------HVSYSPDFNTMTHLLENLKG S------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------GISAGTE------------------------LRSP------------------ -----------CECESLVEF---------------------------------------- ------------------------------------------------------------ QGRTLGALES-LTQN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LARLTERLEELEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLASRK------------------------------------- ------------------- >XP_425698.5 matrilin-4 [Gallus gallus] ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MK--LLPLAALLLLILTAL- EARPKP------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------A--ALKCRTGPLDIVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRRFMIDIIGNLD----VGPNATRVGVIQ--YSSQVQNIFSLKTFFTR-AEMERAI NSIVPLAQGTMTGLAIQYAMNVAFTVQEGARPPHKKIPRIAIIVTDGRPQDRVSEVAAH- -ARNAGIEIYAV--GI-QRADMNSLRAMASPPLE-EHVFLVESFELIQQF---------- ------------------------------------------------------------ -----------------------GKQFQDKLC-------------GVDMCMERDHGCQHS CVSTPGSFYCECHPGYQLNVDGKTCSPIDACADGRHGCEH-------------------- ---------------------HCISARGT------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YSCRCRAGY------------------ ------------------------------------------------------------ ----------------------------------------------YLNQDRRSCTMIDY CSFGNHSCQHDCVSIPAG-HRCRCRDGFMLQHDGKSCRAIDLCNGVDHGCEFKCVSSEGS FHCVCPEGQQ-----------LQADGKTCSK------C---GAGHVDLVM---------- -VIDGSKSVRPQNFELVKQFVNRIVDLLE-VSPDGTHVGLVQYSSRVRTEF-PLNKYHSA EEIKAAVMKMEYMEKGTMTGLALKHMVEHSFSELEGARPLSHNVPRIGLVFTD------- --GRSQD----------------------------------------------------- ----------------DISEWA-------------------------------------- ---QRAKESGIVMFAVGV------------------------------------------ --GKAVE-------------------EELRAIASE------------------------- --PVEQ----------------------------------HFSYSADFTTMTHLVENFKL N------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------GRGETE------------------------IRSP------------------ -----------CECEALVQF---------------------------------------- ------------------------------------------------------------ QTNTVAILQS-LTER--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------IAQMTARLEALEK-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QIALKK------------------------------------- ------------------- >XP_009435567.1 matrilin-4 isoform X1 [Pan troglodytes] ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MRGLLCW--LMLLLLLQPW- ETQLQL------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------T--GPRCHTGPLDLVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRQFLMGLLPGLN----VGPNATRVGVIQ--YSSQVQSVFPLRAFSRR-EDMERAI RDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQ- -ARARGIEIYAV--GV-QRADVGSLRAMASPPLD-EHVFLVESFDLIQEF---------- ------------------------------------------------------------ -----------------------GLQFQSRLC---------------------------- --------------------------AIDLCAEGTHGCEH-------------------- ---------------------HCVNSPGS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YFCRCQVGF------------------ ------------------------------------------------------------ ----------------------------------------------VLQQDQRSCRAIDY CSFGNHSCQHECVSTPGG-PRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLS YRCLCPEGRQ-----------LQADGKSCNR------C---REGHVDLVL---------- -LVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF-PLGRYGTA AEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------DISVWA-------------------------------------- ---ARAKEEGIVVYAVGV------------------------------------------ --GKAVE-------------------AELREIASE------------------------- --PAEL----------------------------------HVSYAPDFGTMTHLLENLRG S------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------GISAGTE------------------------LRSP------------------ -----------CECESLVEF---------------------------------------- ------------------------------------------------------------ QGRTLGALES-LTLN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LAQLTARLEDLEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLANQK------------------------------------- ------------------- >XP_005635167.1 matrilin-4 isoform X1 [Canis lupus familiaris] -----------------------------------------------------------M RPPPPLA-----PA----------AWQSPAWARCLRRYL-VQLPG--RLRPSAPLCGRAS ELSGR------------------------------LSA--MRGLLCWPLPVLLFLLQPW- ETLSQF------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------A--GPRCRTGPLDLVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRQFLVGLLRGLD----VGPNATRVGVIQ--YSSQVQSVFPLGAFSRR-EDMERAI RALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRIAVIVTDGRPQDRVAEVAAQ- -ARARGIEIYAV--GV-QRADVGSLRAMASPPLD-EHVFLVESFNLIQEF---------- ------------------------------------------------------------ -----------------------GQQFRGRLC-------------GKDLCAEGRHGCQHQ CVSTPGTFRCACNPGYQLAEDNKSCLAIDLCTGGTHGCEH-------------------- ---------------------HCISSPGS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YFCRCRAGF------------------ ------------------------------------------------------------ ----------------------------------------------VLQQDQRSCRAIDH CGFGNHSCQHECVSTFGG-PRCRCREGHDLLPDGRSCQARDLCNGVDHGCEFQCVSEGLS YRCLCPEGQQ-----------LQADGKSCNH-----GC---REGHVDLVL---------- -LVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF-PLGRYGTA AEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------DISVWA-------------------------------------- ---RRAKEEGIVMYAVGV------------------------------------------ --GKAVE-------------------EELRQIASE------------------------- --PAEL----------------------------------HVSYSPDFGTMTHLLENLRG S------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------GIGAGTE------------------------LRNL------------------ -----------CECESLVEF---------------------------------------- ------------------------------------------------------------ QGRTLGALEK-LTQN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LAQLTARLEDLEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLATQK------------------------------------- ------------------- >NP_001162037.1 matrilin-4 precursor [Pongo abelii] ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MRGLLCW--PLLLLLLQPW- ETQLQL------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------A--GPRCHTGPLDLVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRQFLMGLLRGLN----VGPNATRVGVIQ--YSSQVQSVFPLRAFSRS-EDMERAI RDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQ- -ARARGIEIYAV--GV-QRADVGSLRAMASPPLD-EHVFLVESFDLIQEF---------- ------------------------------------------------------------ -----------------------GLQFQSRLC---------------------------- --------------------------AIDLCAEGTHGCEH-------------------- ---------------------HCVNSPGS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YFCRCQVGF------------------ ------------------------------------------------------------ ----------------------------------------------VLQQDQRSCRAIDY CSFGNHSCQHECVSTPGG-PQCHCREGHDLQPDGRSCQVQDLCNGVDHGCEFQCVSEGLS YRCLCPEGRQ-----------LQADGKSCNR------C---REGHVDLVL---------- -LVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF-PLGRYGTA AEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------DISVWA-------------------------------------- ---ARAKEEGIVMYAVGV------------------------------------------ --GKAVE-------------------AELREIASK------------------------- --PAEL----------------------------------HVSYAPDFGTMTHLLENLRG S------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------GISAGTE------------------------LRSP------------------ -----------CECESLVEF---------------------------------------- ------------------------------------------------------------ QGRTLGALES-LTLN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LAQLTARLEDLEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLANQK------------------------------------- ------------------- >NP_001178240.2 matrilin-4 precursor [Bos taurus] ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MRGLLYSLLPLLLLLLQPW- ETQLQL------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------A--GPRCSSGPLDLVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRQFLVGLLRSLD----VGPNATRVGVIQ--YSSQVQSVFPLRAFSRR-EDMERAI RAVVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEAHVPRVAVIVTDGRPQDRVAEVAAQ- -ARARGIEIYAV--GV-QRADVGSLRAMASPPLN-EHVFLVESFDLIQEF---------- ------------------------------------------------------------ -----------------------GRQFQGRLC-------------TLDLCTEGDHGCEHQ CVS--------------------------------------------------------- -------------------------MPGS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YFCRCQAGF------------------ ------------------------------------------------------------ ----------------------------------------------VLQQEQRSCRAIDH CSFGNHSCQHDCVSIYGG-PQCRCREGYDLLPDGRSCQARDLCNGVDHGCEFQCVSEGFS YRCVCPEGRQ-----------LQADGKSCSR------C---REGHVDLVL---------- -LVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF-PLGRYGTA AEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------NISVWA-------------------------------------- ---ARAKEEGIVMYAVGV------------------------------------------ --GKAVE-------------------EELREIASE------------------------- --PAEL----------------------------------HVSYSPDFSTMTHLLENLKG S------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------GIGAGTE------------------------LRSP------------------ -----------CECESLVEF---------------------------------------- ------------------------------------------------------------ QGRTLGALESFLNLP--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LAQLTARLEDLEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLATQK------------------------------------- ------------------- >XP_017206222.1 PREDICTED: matrilin-4 isoform X1 [Oryctolagus cuniculus] ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MRGLLCWPLLVLLLLAQPW- EAQPQFT----------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ --------DLP------------------------------------------------- -----------------------DRPA--GPKCHTGPLDLVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PL EFETMRRFLVGLVRSLD----VGPNATRVGVIQ--YSSQVQSVFPLGAFSRR-EDMERAL RTLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQ- -ARARGIEIYAV--GV-QRADVGSLRAMASPPLD-EHVFLVESFDLIQEF---------- ------------------------------------------------------------ -----------------------GRQFRGRLC-------------GKAPCAEGRHGCQHQ CVNTQGAVRCACNPGYKLAADNKSCLAIDPCAEGTHGCDH-------------------- ---------------------HCVSSPGS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YFCRCQAGF------------------ ------------------------------------------------------------ ----------------------------------------------VLLQDQRSCRAVDP CSLSNHSCQHECVSTLDG-PHCRCPDGHDLQPDGRSCRIRDLCNSVDHGCEFQCVSEGLS YRCLCPEGRP-----------LEADGKSCSRTSRAAGC---REGHVDLVL---------- -LVDGSKSVRPQNFELVKRFVTQIVDFLD-VSPEGTRVGLVQFSSRVRTEF-PLGRYGTA AELKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------DISVWA-------------------------------------- ---ARAKEEGIVMYAVGV------------------------------------------ --GKAVE-------------------EELREIASE------------------------- --PAEL----------------------------------HVSYSPDFSTMTHLLENLKG S------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------GVGAGTE------------------------LRSP------------------ -----------CDCDSLVEF---------------------------------------- ------------------------------------------------------------ QGRALGSLES-LTHR--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LAQLTARLEDLES-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------LLAGQK------------------------------------- ------------------- >XP_020933255.1 matrilin-4 [Sus scrofa] MPRRLPTH-------SGSAERSRPASRCSPIPAPQFASAA-PGVAGAG--------GAAL APPQPPEEGGSLPASGRGRGPRSFSPPASPRVKCGRRLRSLQLPGGPHLRQAARAVTWSN CPGGSARRL----RSAAAPRSCPAGSGPDSSALCSPSA--MRGLLGLLLPLLLLLLQPW- ETQLQF------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------A--GPRCRTGPLDLVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRQFLVGLLRSLD----VGPNATRVGVIQ--YSSQVQSVFPLGAFSRR-EDMEGAI RALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVAAQ- -ARSRGIEIYAV--GV-QRADVGSLRAMASPPLD-EHVFLVESFDLIQEF---------- ------------------------------------------------------------ -----------------------GQQFQGRLC-------------RKDLCAEGGHGCQHQ CVSAPGTFHCACNPGYRLAADNKSCLAINLCAEETHGCEH-------------------- ---------------------HCVSSPGS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YFCHCRAGF------------------ ------------------------------------------------------------ ----------------------------------------------VLQQDQRSCRAIDY CGFGNHSCQHECVNTFGG-PRCRCREGHDLLPDGRSCQARDLCNGVDHGCEFQCVSEGLS YRCLCPEGQQ-----------LLADGKSCNR------C---REGHVDLVL---------- -LVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF-PLGRYGTA AEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------DVSVWA-------------------------------------- ---ARAKEEGIVMYAVGV------------------------------------------ --GKAVE-------------------EELREIASE------------------------- --PAEL----------------------------------HVSYSPDFSTMTHLLENLKG S------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------GIGAGTE------------------------LRSP------------------ -----------CECDSLVEF---------------------------------------- ------------------------------------------------------------ QGRTLGALES-LSQN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LAQLTARLEELEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLAAQK------------------------------------- ------------------- >XP_010720616.1 matrilin-4 [Meleagris gallopavo] ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MK--LLPLAAFLLLVLTAL- EARPKP------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------A--ALKCRTGPLDIVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRRFMIDIIGNLD----VGPNATRVGVIQ--YSSQVQNIFSLKTFFTR-AEMERAI NSIVPLAQGTMTGLAIQYAMNVAFTVQEGARPPHKKIPRIAIIVTDGRPQDRVSEVAAH- -ARNAGIEIYAV--GI-QRADMNSLRAMASPPLE-EHVFLVESFELIQQF---------- ------------------------------------------------------------ -----------------------GKQFQDKLC-------------GVDMCMEQDHGCQHS CVSTPSSFYCECHPGYQLNVDGKTCSPIDACADGRHGCEH-------------------- ---------------------HCISTRGT------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YSCRCRAGY------------------ ------------------------------------------------------------ ----------------------------------------------HLNQDKRSCTMIDY CSFGNHSCQHDCVSIPAG-HRCRCRDGFMLQHDGKSCRAIDLCNGVDHGCEFKCVSSEGS FHCVCPEGQQ-----------LHADGKTCNK------C---GAGHVDLVM---------- -VIDGSKSVRPQNFELVKQFVNRIVDLLE-VSPDGTRVGLVQYSSRVRTEF-PLNKYHSA EEIKEAVMKMEYMEKGTMTGLALKHMVEHSFSELEGARPLSHNVPRIGLVFTD------- --GRSQD----------------------------------------------------- ----------------DISEWA-------------------------------------- ---QRAKESGIVMFAVGV------------------------------------------ --GKAVE-------------------EELRAIASE------------------------- --PVEQ----------------------------------HFSYSADFTTMTNLVENFKL N------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------GRGETE------------------------IRSP------------------ -----------CECEALVQF---------------------------------------- ------------------------------------------------------------ QTNTVAILQS-LTER--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------IAQMTARLEALEK-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QIALKK------------------------------------- ------------------- >XP_008949583.1 matrilin-4 isoform X1 [Pan paniscus] ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MRGLLCW--LMLLLLLQPW- ETQLQL------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------T--GPRCHTGPLDLVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRQFLMGLLPGLN----VGPNATRVGVIQ--YSSQVQSVFPLRAFSRR-EDMERAI RDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQ- -ARARGIEIYAV--GV-QRADVGSLRAMASPPLD-EHVFLVESFDLIQEF---------- ------------------------------------------------------------ -----------------------GLQFQSRLC---------------------------- --------------------------AIDLCAEGTHGCEH-------------------- ---------------------HCVNSPGS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YFCRCQVGF------------------ ------------------------------------------------------------ ----------------------------------------------VLQQDQRSCRAIDY CSFGNHSCQHECVSTPGG-PRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLS YRCLCPEGRQ-----------LQADGKSCNR------C---REGHVDLVL---------- -LVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF-PLGRYGTA AEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------DISVWA-------------------------------------- ---ARAKEEGIVMYAVGV------------------------------------------ --GKAVE-------------------AELREIASE------------------------- --PAEL----------------------------------HVSYAPDFGTMTHLLENLRG S------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------GISAGTE------------------------LRSP------------------ -----------CECESLVEF---------------------------------------- ------------------------------------------------------------ QGRTLGALES-LTLN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LAQLTARLEDLEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLANQK------------------------------------- ------------------- >XP_023106971.1 matrilin-4 isoform X1 [Felis catus] ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MRGLLCSPRLMLLLLLQPW- ESQLQF------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------A--GPRCRTGPLDLVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRQFLVGLLRGLD----VGPNATRVGVIQ--YSSQVQSVFRLGAFSRR-EDMERAI RALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRIAVIVTDGRPQDRVAEVAAQ- -ARARGIEIYAV--GV-QRADVGSLRAMASPPLD-EHVFLVESFDLIQEF---------- ------------------------------------------------------------ -----------------------GLQFQGRLC-------------GKDLCVEGGHGCQHQ CVSALGTFHCACNPGYQLAEDNKSCLAIDLCAEGTHGCEH-------------------- ---------------------HCISSPGS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YSCRCRAGF------------------ ------------------------------------------------------------ ----------------------------------------------VLQQDQRSCRAIDH CSFGNHSCQHECVSTFRG-PRCHCREGHDLLPDGRSCQARDLCNGVDHGCEFQCVSEGLS YRCLCPEGQQ-----------LQADGKSCNR------C---REGHVDLVL---------- -LVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF-PLGRYGTA AEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------DISVWA-------------------------------------- ---ARAKEEGIVMYAVGV------------------------------------------ --GKAVE-------------------EELRQIASE------------------------- --PAEL----------------------------------HVSYSPDFGSMTHLLENLRG S------------------------------------------ICPDSHSPDSL------ CPAGR-------------------GGHRR-------GYRASEPVRMR-KPRGVP------ -GSHAGG--------------------------------AREANAEPG------------ -----PAG---GAPGGSGEPVGQPEVRAAGGSE--------------PGRDAALRTG--- -SPVCRRGAGAGQHR------GPGGLGWRGGGAGGLPALRSSWPRLDQKPDCGGRRR--- ELAPHAVA--LCCAQFFVGFPFCFLFLKKKKKKKKNFFFFSTGSVCGSCSAARGRGGQ-- ----TERAPEAPGRRLLG----------------ERRFVRGVG--LGGRGPGAASPSLFI QPRTDGSLCA-LREGRG------------------------------------------L DANPRGPN---------------------------------------------------E TAPLHT----------------------------PPPA---------------------- -PEGPA---------------LRSLVLRISWCP--------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QIRLKSC------------------------------------ ------------------- >XP_014955384.2 matrilin-4 isoform X1 [Ovis aries] -----------------------------------------------------------M RPPPPPA-----PA----------ARPSPPRAHCPCRYL-VQLPG--RLRPSAPLCGRAS ELSGRLRL--------------------DTSVLCWLSA--MRGLLYSMLPLLLLLLQPW- ETQLQL------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------A--GPRCSTGPLDLVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRQFLVGLLRSLD----VGPNATRVGVIQ--YSSQVQSVFPLRAFSRR-EDMERAI RALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVAAQ- -ARARGIEIYAV--GV-QRADVGSLRAMASPPLN-EHVFLVESFDLIQEF---------- ------------------------------------------------------------ -----------------------GRQFQGRLC-------------RKDLCAQGGHGCQHQ CVSALGTFHCACNPGYQLAADNKSCM---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------AIDH CSFGNHSCQHDCVSTFGG-PQCRCREGYDLLPDRRSCQARDLCNGVDHGCEFQCVSEGFS YHCVCPEGRQ-----------LQADGKSCSR------C---REGHVDLVL---------- -LVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF-PLGRYGTA AEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRELNVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------NISVWA-------------------------------------- ---ARAKEEGIVMYAVGV------------------------------------------ --GKAVE-------------------EELREIASE------------------------- --PAEL----------------------------------HVSYSPDFSTMTHLLENLKG S------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------GIGAGTE------------------------LRSP------------------ -----------CECESLVEF---------------------------------------- ------------------------------------------------------------ QGRTLGTLES-LSQK--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LAQLTARLEDLEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLATQK------------------------------------- ------------------- >XP_018872360.1 matrilin-4 isoform X1 [Gorilla gorilla gorilla] ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MRGLLCW--PVLLLLLQPW- ETQLQL------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------T--GPRCHTGPLDLVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETVRQFLMGLLRGLN----VGPNATRVGVIQ--YSSQVQSVFPLRAFSRR-EDMERAI RDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQ- -ARARGIEIYAV--GV-QRADVGSLRAMASPPLD-EHVFLVESFDLIQEF---------- ------------------------------------------------------------ -----------------------GLQFQSRLC---------------------------- --------------------------AIDLCAEGTHGCEH-------------------- ---------------------HCVNSPGS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YFCRCQVGF------------------ ------------------------------------------------------------ ----------------------------------------------VLQQDQRSCRAIDY CSFGNHSCQHECVSTPGG-PRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLS YHCLCPEGRQ-----------LQADGKSCNR------C---REGHVDLVL---------- -LVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF-PLGRYGTA AEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------DISVWA-------------------------------------- ---ARAKEEGIVMYAVGV------------------------------------------ --GKAVE-------------------AELREIASE------------------------- --PAEL----------------------------------HVSYAPDFGTMTHLLENLRG S------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------GISAGTE------------------------LRSP------------------ -----------CECESLVEF---------------------------------------- ------------------------------------------------------------ QGRTLGALES-LTLN--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LAQLTARLEDLEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLANQK------------------------------------- ------------------- >XP_023811128.1 matrilin-4 [Oryzias latipes] ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MRP-LRASRVFVLLGLVVLT AARPRA------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------G-PDQKCKPGPLDLIFLI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PH EFETMRKFMIDILNSLE----IGPDSTRVGVVQ--YSSQVRSEFSLKTHGDL-ESVVAGI RQIVPLAQGTMTGLAIRYMMNEAFTAEQGDRP---KVPNVAVIVTDGRPQDRVAEVAAE- -ARERGIEIFAV--GV-ARADMTSLRAMASLPFE-DHVFLEESFDLIHQF---------- ------------------------------------------------------------ -----------------------GLQFQDAFC-------------GLDLCKEMDHGCEHV CENSPGSFHCLCSEGYTLNEDGKTCTAIDLCAEGKHDCEQVCISSPGNFSCDCREGYRLQ DDGRTCSMVEFCSFGNDSCDHHCVNMLNG------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------FYCTCKEGHRLQADGKTCQAIDLCAEG KHDCQQVCMNM------------------------------------------------- ---------------------------------GPAVFTCDCNEGYTLNEDERSCTPIDL CAEGKHDCEQVCISAPGV-FTCDCRKGFRLNHDKKTCTNMEMCSSVQHGCEHQCVNTPGS YYCVCPEGQL-----------LQDDGKSCGA------C---TSANIDLVL---------- -LIDGSKSVRPQNFELVKKFVNQVVDSLD-VSAHGTRVGLVQYSSRVRTEF-PLNMYHTA EDIKAAVMKVEYMEKGTMTGLALKHMLENSFSEAEGARPAARSVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------DISEYA-------------------------------------- ---KKAKEAGITMYAVGV------------------------------------------ --GKAVE-------------------DELREIASE------------------------- --PVEK----------------------------------HFYYTTDFNAISTIADNLKL N------------------------------------------VCPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------SQGEVE------------------------VKDP------------------ -----------CACENLVEF---------------------------------------- ------------------------------------------------------------ QQNTGSSLEQ-LTQK--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LAAMNTRLVELEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLLSRK------------------------------------- ------------------- >XP_021143581.1 matrilin-4 [Columba livia] MQGKA--------------------------------MQC-------------------R AIPP-----------------------SP------------------------------- -------------------------------GIVWSCRIMMK--LLPVAPLLLLLLMTL- EARPKP------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------A--ALKCRTGPMDIVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRQFMMDIIGSLD----VGPNATRVGVIQ--YSSQVQNIFSLKTFFTR-ADMEKAI NSIVPLAQGTMTGLAIQYAMNVAFTTQEGARPLHKKIPRIAIIVTDGRPQDRVTEVATQ- -ARNAGIEIYAV--GI-QRADMNSLRAMASPPLE-EHVFLVESFELIQQF---------- ------------------------------------------------------------ -----------------------GKQFQDKLC-------------GVDMCVEREHGCQHS CISTPGSFYCECNPGYRLNMDGRTCSPIDACADGRHGCQH-------------------- ---------------------HCISARGS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YSCRCRAGY------------------ ------------------------------------------------------------ ----------------------------------------------YLNQDKRSCTMIDY CSFGNHSCQHECVSIPSG-HYCRCRSGFTLQPDGRSCRATDLCNGVDHGCEFKCVSTDGS YHCVCPDGQQ-----------LQADGKACSK------C---GSGHVDLVM---------- -VIDGSKSVRPQNFELVKQFVNRIVDLLE-VSPHGTRVGLVQYSSRVRTEF-PLNKYHSA DEIKKAVMEVEYMEKGTMTGLALKHMVEHSFSELEGARPLSHNVPRIGLVFTD------- --GRSQD----------------------------------------------------- ----------------DISEWA-------------------------------------- ---RRAKESGIVMFAVGV------------------------------------------ --GKAVE-------------------EELRAIASE------------------------- --PVEQ----------------------------------HFSYSADFTTMTHLVENFKL N------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------SKGETE------------------------IRSP------------------ -----------CECEALVQF---------------------------------------- ------------------------------------------------------------ QTNTVAILQS-LTEK--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------IAQMTARLEDLEK-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QIAKKK------------------------------------- ------------------- >XP_017913405.1 PREDICTED: matrilin-4 [Capra hircus] -----------------------------------------------------------M RPPPPPA-----PA----------ARPSPPRAHCPCRYL-VQLPG--RLRPSAPLCGRAS ELSGRLRL--------------------HTSVLCWLSA--MRGLLYSMLPLLLLLLQPW- ETQLQL------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------A--GPRCSTGPLDLVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRQFLVGLLRSLD----VGPNATRVGVIQ--YSSQVQSVFPLRAFSRR-EDMERAI RALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVAAQ- -ARARGIEIYAV--GV-QRADVGSLRAMASPPLN-EHVFLVESFDLIQEF---------- ------------------------------------------------------------ -----------------------GRQFHGRLC-------------RKDLCAQGGHGCQHQ CVSALGTFHCACNPGYQLAADNKSCM---------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------------AIDH CSFGNHSCQHDCVSTFGG-PQCRCREGYDLLPDRRSCQARDLCNGVDHGCEFQCVSEGFS YHCVCPEGRQ-----------LQADGKSCSR------C---REGHVDLVL---------- -LVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF-PLGRYGTA AEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRELNVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------NISVWA-------------------------------------- ---ARAKEEGIVMYAVGV------------------------------------------ --GKAVE-------------------EELREIASE------------------------- --PAEL----------------------------------HVSYSPDFSTMTHLLENLKG S------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------GIGAGTE------------------------LRSP------------------ -----------CECESLVEF---------------------------------------- ------------------------------------------------------------ QGRTLGTLES-LSQK--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LAQLTARLEDLEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLATQK------------------------------------- ------------------- >XP_043335876.1 matrilin-4 isoform X2 [Cervus canadensis] ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MRGLLYSLLPLLLLLLQPW- ETQLQF------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------A--GPRCSTGPLDLVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRQFLVGLLRSLD----VGPNATRVGVIQ--YSSQVQSVFPLRAFSRR-EDMERAI RALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVAAQ- -ARARGIEIYAV--GV-QRADVGSLRAMASPPLN-EHVFLVESFDLIQEF---------- ------------------------------------------------------------ -----------------------GRQFQGRLC-------------RKDLCAQGGHGCQHQ CVSAPGTFHCACNPGYQLAADNKSCVALDLCTERDRGCGH-------------------- ---------------------HCVRIPGS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YFCRCQAGF------------------ ------------------------------------------------------------ ----------------------------------------------VLRQDQRSCRAIDH CSFGNHSCQHDCVSTFGG-PQCRCREGYDLLPDGRSCQARDLCNGVDHGCEFQCVSEGFS YRCMCPEGRQ-----------LQADGKSCSR------C---REGHVDLVL---------- -LVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF-PLGRYGTA AEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------NISVWA-------------------------------------- ---ARAKEEGIVMYAVGV------------------------------------------ --GKAVE-------------------EELREIASE------------------------- --PAEL----------------------------------HVSYSPDFSTMTHLLENLKG S------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------GIGAGTE------------------------LRSP------------------ -----------CECESLVEF---------------------------------------- ------------------------------------------------------------ QGRTLGALES-LSQK--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LAQLTARLEDLEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLATQK------------------------------------- ------------------- >XP_043740388.1 matrilin-4 isoform X2 [Cervus elaphus] ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MRGLLYSLLPLLLLLLQPW- ETQLQF------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------A--GPRCSTGPLDLVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRQFLVGLLRSLD----VGPNATRVGVIQ--YSSQVQSVFPLRAFSRR-EDMERAI RALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVAAQ- -ARARGIEIYAV--GV-QRADVGSLRAMASPPLN-EHVFLVESFDLIQEF---------- ------------------------------------------------------------ -----------------------GRQFQGRLC-------------RKDLCAQGAHGCQHQ CVSAPGTFHCACNPGYQLAADNKSCVALDLCTERDRGCGH-------------------- ---------------------HCVRIPGS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YFCRCRAGF------------------ ------------------------------------------------------------ ----------------------------------------------VLRQDQRSCRAIDH CSFGNHSCQHDCVSTFGG-PQCRCREGYDLLPDGRSCQARDLCNGVDHGCEFQCVSEGFS YRCMCPEGRQ-----------LQADGKSCSR------C---REGHVDLVL---------- -LVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF-PLGRYGTA AEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------NISVWA-------------------------------------- ---ARAKEEGIVMYAVGV------------------------------------------ --GKAVE-------------------EELREIASE------------------------- --PAEL----------------------------------HVSYSPDFSTMTHLLENLKG S------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------GIGAGTE------------------------LRSP------------------ -----------CECESLVEF---------------------------------------- ------------------------------------------------------------ QGRTLGALES-LSQK--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LAQLTARLEDLEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLATQK------------------------------------- ------------------- >KAB0351307.1 hypothetical protein FD754_016164 [Muntiacus muntjak] ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MRGLLYSLLPLLLLLLQPW- ETQLQF------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------A--GPRCSTGPLDLVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRQFLVGLLRSLD----VGPNATRVGVIQ--YSSQVQSVFPLRAFSRR-EDMERAI RALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVAAQ- -ARARGIEIYAV--GV-QRADVGSLRAMASPPLN-EHVFLVESFDLIQEF---------- ------------------------------------------------------------ -----------------------GRQFQGRLC-------------RKDLCAQGGHGCQHQ CVSAPGTFHCACNPGYQLAADNKSCVALDLCTERDRGCGH-------------------- ---------------------HCVSIPGS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YFCRCRAGF------------------ ------------------------------------------------------------ ----------------------------------------------VLRQDQRSCRAIDH CSFGNHSCQHDCVSTFGG-PQCRCREGYDLLPDGRSCQARDLCNGVDHGCEFQCVSEGFS YRCMCPEGRQ-----------LQADGKSCSR------C---REGHVDLVL---------- -LVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF-PLGRYGTA AEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------NISVWA-------------------------------------- ---ARAKEEGIVMYAVGV------------------------------------------ --GKAVE-------------------EELREIASE------------------------- --PAEL----------------------------------HVSYSPDFSTMTHLLENLKG S------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------GIGAGTE------------------------LRSP------------------ -----------CECESLVEF---------------------------------------- ------------------------------------------------------------ QGRTLGALES-LSQKHI------------------------------------------L WS---------------------------------------------------------- ------------------------------------------------------------ ----PGVFL---------NLSLAQLTARLEDLEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLATQK------------------------------------- ------------------- >KAB0381538.1 hypothetical protein FD755_003455 [Muntiacus reevesi] ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MRGLLYSLLPLLLLLLQPW- ETQLQF------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------A--GPRCSTGPLDLVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRQFLVGLLRSLD----VGPNATRVGVIQ--YSSQVQSVFPLRAFSRR-EDMERAI RALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVAAQ- -ARARGIEIYAV--GV-QRADVGSLRAMASPPLN-EHVFLVESFDLIQEF---------- ------------------------------------------------------------ -----------------------GRQFQGRLC-------------RKDLCAQGGHGCQHQ CVSAPGTFHCACNPGYQLAADNKSCVALDLCTERDRGCGH-------------------- ---------------------HCVSIPGS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YFCRCRAGF------------------ ------------------------------------------------------------ ----------------------------------------------VLRQDQRSCRAIDH CSFGNHSCQHDCVSTFGG-PQCRCREGYDLLPDGRNCQARDLCNGVDHGCEFQCVSEGFS YRCMCPEGRQ-----------LQADGKSCSR------C---REGHVDLVL---------- -LVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF-PLGRYGTA AEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------NISVWA-------------------------------------- ---ARAKEEGIVMYAVGV------------------------------------------ --GKAVE-------------------EELREIASE------------------------- --PAEL----------------------------------HVSYSPDFSTMTHLLENLKG S------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------GIGAGTE------------------------LRSP------------------ -----------CECESLVEF---------------------------------------- ------------------------------------------------------------ QGRTLGALES-LSQKHI------------------------------------------L WS---------------------------------------------------------- ------------------------------------------------------------ ----PGVFL---------NLSLAQLTARLEDLEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLATQK------------------------------------- ------------------- >KAF4023671.1 hypothetical protein G4228_015599 [Cervus hanglu yarkandensis] ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MRGLLYSLLPLLLLLLQPW- ETQLQF------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------A--GPRCSTGPLDLVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRQFLVGLLRSLD----VGPNATRVGVIQ--YSSQVQSVFPLRAFSRR-EDMERAI RALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVAAQ- -ARARGIEIYAV--GV-QRADVGSLRAMASPPLN-EHVFLVESFDLIQEF---------- ------------------------------------------------------------ -----------------------GRQFQGRLC-------------RKDLCAQGGHGCQHQ CVSAPGTFHCACNPGYQLAADNKSCVALDLCTERDRGCGH-------------------- ---------------------HCVRIPGS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YFCRCRAGF------------------ ------------------------------------------------------------ ----------------------------------------------VLRQDQRSCRAIDH CSFGNHSCQHDCVSTFGG-PQCRCREGYDLLPDGRSCQARDLCNGVDHGCEFQCVSEGFS YRCMCPEGRQ-----------LQADGKSCSR------C---REGHVDLVL---------- -LVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF-PLGRYGTA AEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------NISVWA-------------------------------------- ---ARAKEEGIVMYAVGV------------------------------------------ --GKAVE-------------------EELREIASE------------------------- --PAEL----------------------------------HVSYSPDFSTMTHLLENLKG S------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------GIGAGTE------------------------LRSP------------------ -----------CECESLVEF---------------------------------------- ------------------------------------------------------------ QGRTLGALES-LSQKHI------------------------------------------L WKGP-------------------------------------------------------- ------------------------------------------------------------ -PRAP----------------EASLTSHWPS----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------- >XP_018093529.1 matrilin-4 isoform X2 [Xenopus laevis] MWCLR----------------------------LQFQFQC--GRG--------------Q HLPPRIK-----------------TCRAPLYSACK-----AGGEGDRTQSFSLSVCDSRV RVTG-----------VSSPALGSTGLNWTQTGLEQSSGLKMK--MFYISTLLLISFATL- DARPQT------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------SGLVQKCKSGPMDLVFII---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRKFMIDIINPLE----VGLSNTRVGVVQ--YSSQVQNVFSLKTFSNK-SDMEKAI NEIIPLAQGTMTGLAIQYAMNVAFTEEEGARPLSKNIPRVAIIVTDGRPQDRVTEVAAQ- -ARDTGIEIYAV--GV-QRADVSSLRTMASHPLD-DHVFHVESFDLIQHL---------- ------------------------------------------------------------ -----------------------SIQFQDKLS-------------CVDMCTEMDHGCQHK CVNIPSSYYCECNEGYKLNADGKTCSLIDLCAQGNHGCEQICVSSPGSYSCACRAGYQLN EDKKTCSLIDLCSQGDHGCEQICVSSPGS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YSCACRAGY------------------ ------------------------------------------------------------ ----------------------------------------------QLNEDKKTCSMIDY CSYGNHSCQHECVSILNG-YYCRCNEGYTLQADGKTCLADDMCNVVDHGCEFKCVSTPGS YYCICPEGQE-----------LQADGKTCNK------C---STGYVDLVL---------- -VIDGSKSVRPQNFELVKEFVINIVDSLA-ISAQGTHIGLVQYSSRVRTEF-SLDQYKNA QDIKTAVKNVQYMEKGTMTGLALKHMVEQSFSEAEGARK---NVPKIGLVFTD------- --GRSQD----------------------------------------------------- ----------------DISEWA-------------------------------------- ---KKAKEAGITMYAVGV------------------------------------------ --GKAVE-------------------DELNEIASE------------------------- --PVNK----------------------------------HSFYTADFSTMNLIAEDLKL N------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------IKGTTE------------------------TKNP------------------ -----------CDCEHLVSF---------------------------------------- ------------------------------------------------------------ QTSTITKLES-LSEQ--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LAQLNARLDDLEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------ELVSKK------------------------------------- ------------------- >XP_006016728.1 matrilin-4 isoform X1 [Alligator sinensis] ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MK--LLLVAPLLLFALTML- EARPKP------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------A--ALKCKTGPLDIVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRRFMIDIIHNLD----VGLNATRVGVIQ--YSSQVQNVFSLKTYFKR-ADMEKAI NSIVPLSQGTMTGLAIQYAMNVAFTTQEGARELHKKIPRVAVIVTDGRPQDRVTEVAAQ- -ARDAGIEIYAV--GV-QRADMNSLRAMASHPLE-QHVFLVESFDLIQQF---------- ------------------------------------------------------------ -----------------------GKQFQDKLC-------------GVDMCTELDHGCQHT CVSVPGSFYCGCNPGYKLNADGKTCSAIDACADGKHGCEH-------------------- ---------------------QCVSARGS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTCRCRLGY------------------ ------------------------------------------------------------ ----------------------------------------------SLNDDKKTCTAINY CNFGNHSCQHECVSLVNG-YYCRCNDGFTLQADGRSCQATDLCNGVDHGCEFKCVSTSGS YHCICPEGQQ-----------LQTDGKTCNK------C---KAGHIDLVL---------- -VIDGSKSVRPQNFELVKQFVNQIVDFLD-VSPHGTRVGLVQYSSRVRTEF-PLNKYKTA NDVKAAVMKVEYMEKGTMTGLALKHMIEHSFSEAEGARPLSQNIPRIGLVFTD------- --GRSQD----------------------------------------------------- ----------------DISEWA-------------------------------------- ---MKAKESGIVMFAVGV------------------------------------------ --GKAVE-------------------EELREIASE------------------------- --PVEQ----------------------------------HFSYSADFSTMTHIVDNLKL N------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------GKGETE------------------------IRSP------------------ -----------CECEALVQF---------------------------------------- ------------------------------------------------------------ QSNTVAILES-LTEK--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LAQMTARLEDLEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QIAKKK------------------------------------- ------------------- >XP_006275851.1 PREDICTED: matrilin-4 [Alligator mississippiensis] ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MK--LLLVAPLLLFALTML- EARPKP------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------A--ALKCKTGPLDIVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRRFMIDIIHNLD----VGLNATRVGVIQ--YSSQVQNVFSLKTYFKR-ADMEKAI NSIVPLSQGTMTGLAIQYAMNVAFTTQEGARELHKKIPRVAVIVTDGRPQDRVTEVAAQ- -ARDAGIEIYAV--GV-QRADMNSLRAMASHPLE-QHVFLVESFDLIQQF---------- ------------------------------------------------------------ -----------------------GKQFQDKLC-------------GVDMCTELDHGCQHI CVSVPGSFYCGCNPGYKLNADGKTCSAIDACADGKHGCEH-------------------- ---------------------QCVSARGS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTCRCRLGY------------------ ------------------------------------------------------------ ----------------------------------------------SLNDDKKTCTAINY CNFGNHSCQHECVSLVNG-YYCRCNDGFTLQADGRSCQATDLCNGVDHGCEFKCVSTSGS YHCICPEGQQ-----------LQTDGKTCNK------C---KAGHIDLVL---------- -VIDGSKSVRPQNFELVKQFVNQIVDFLD-VSPHGTRVGLVQYSSRVRTEF-PLNKHKTA NDVKAAVMKVEYMEKGTMTGLALKHMIEHSFSEAEGARPLSQNIPRIGLVFTD------- --GRSQD----------------------------------------------------- ----------------DISEWA-------------------------------------- ---RKAKESGIVMFAVGV------------------------------------------ --GKAVE-------------------EELREIASE------------------------- --PVEQ----------------------------------HFSYSADFSTMTHIVDNLKL N------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------GKGETE------------------------IRSP------------------ -----------CECEALVQF---------------------------------------- ------------------------------------------------------------ QSNTVAILES-LTEK--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LAQMTARLEDLEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QIAKKK------------------------------------- ------------------- >XP_015813978.1 PREDICTED: matrilin-4 isoform X1 [Nothobranchius furzeri] ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MK--MRTLSVLVLLTLAVLT TARPKA------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------G-AEQKCKSGPVDLVFLI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PH EFETMRKFMIDILDTLD----IGLDTTRVGVVQ--YSSQVRSEFSLKTHSKL-ENMVKAI NEIIPLAQGTMTGLAIRYLMNEAFSPEQGDRP---EVPNVAVIVTDGRPQDRVAEVAAE- -AREKGIEIFAV--GV-ARADMTSLRAMASPPFE-DHVFLVERFDLIYQF---------- ------------------------------------------------------------ -----------------------GLQFQNKLC-------------GLDLCVESDHGCEHL CESSPGSYHCLCLPGYTLNDDGKTCTAIDLCAEGKHNCEQICISSPGSLTCDCNQGYHLN EDKKTCSAINLCAEGKHDCGQVCVNMGPA------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------IFTCDCSEGYRLNEDEKTCSAIDVCAEG KHDCGQVCVNM------------------------------------------------- ---------------------------------GPGIFTCDCSEGYRLNEDEKTCSAIDL CAEGKHDCEQMCISTPGA-FTCDCNKGFKLNDDKKTCTNMDMCNTVAHGCEHQCVNTPGS FHCICPEGQP-----------LQDDGKSCGT------C---KSAVIDLVL---------- -LIDGSKSVRPQNFELVKKFVNQVVDTLD-LSAHGTRVGLVQYSSRVRTEF-PLNKYHTA EEIKAAVMKVEYMEKGTMTGLALKHMLENSFSEAEGARPASRNIPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------DISEYA-------------------------------------- ---KKAKEAGITMYAVGV------------------------------------------ --GKAVE-------------------EELREIASE------------------------- --PVEK----------------------------------HFYYTTDFSAISTIAENLKL N------------------------------------------VCPAE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------SQGEIE------------------------VKDP------------------ -----------CACENLVEF---------------------------------------- ------------------------------------------------------------ QQATMSSLQQ-LTQK--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LTSMAARLEQLEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLLSRK------------------------------------- ------------------- >XP_020767141.1 matrilin-4 [Odocoileus virginianus texanus] ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MRRLLYSLLPLLLLLLQPW- ETQLQF------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------A--GPRCSTGPLDLVFVI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFETMRQFLVGLLRSLD----VGPNATRVGVIQ--YSSQVQSVFPLRAFSRR-EDMERAI RALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVAAQ- -ARARGIEIYAV--GV-QRADVGSLRAMASPPLN-EHVFLVESFDLIQEF---------- ------------------------------------------------------------ -----------------------GRQFQGRLC---------------------------- --------------------------PLDLCTKRDHSCGH-------------------- ---------------------HCISVPGS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YFCQCQAGF------------------ ------------------------------------------------------------ ----------------------------------------------VLQQDQRSCRAIDH CSFGNHSCQHDCVSTFGG-PQCRCREGYDLLPDGRSCQARDLCNGVDHGCEFQCVSEGFS YRCMCPEGRQ-----------LQADGKSCSR------C---REGHVDLVL---------- -LVDGSKSVRPQNFELVKRFVNQIVDFLD-VSPEGTRVGLVQFSSRVRTEF-PLGRYGTA AEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTD------- --GRSQD----------------------------------------------------- ----------------NISVWA-------------------------------------- ---ARAKEEGIVMYAVGV------------------------------------------ --GKAVE-------------------EELREIASE------------------------- --PAEL----------------------------------HVSYSPDFSTMTHLLENLKG S------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------GIGAGTE------------------------LRSP------------------ -----------CECESLVEF---------------------------------------- ------------------------------------------------------------ QGRTLGALES-LSQK--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LAQLTARLEDLEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLATQK------------------------------------- ------------------- >XP_030275675.1 matrilin-4 isoform X1 [Sparus aurata] ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MK--MRQLRGFILLTLAVLA AARPKA------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------G-PEQKCKSGPVDLVFLI---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PH EFETMRKFMIDILATLD----IGLNATRVGVVQ--YSSQVRSEFSLKTHAKL-ETMVKGI NEIIPLAQGTMTGLAIKYVMNNAFTAEAGDRP---KVPNVVVIVTDGRPQDRVAEVAAE- -AREKGIEIYAV--GV-ARADMTSLRAMASPPFE-DHVFLVESFDLIHQF---------- ------------------------------------------------------------ -----------------------GLQFQDKLC-------------GMDLCLESDHGCEHI CESSPGSFHCLCLPGYTLNDDGKTCAAIDLCAEGKHDCEQICVSSPGSFTCDCNKGYKLN DDKKTCSMIDYCSFGNHSCDHECVSVLNG------------------------------- ---------------------------------------------------YHCR----- --------------------------------CNDGYRLLDDGKTCQAIDLCAE------ ------------------------------------GKHDCEQICVSAPGVFTCDCNQGY TLNKDEKTCTPIDLCAEG-KHDCEQICVSAPGVFTCDCNQGYTLNKDEKTCTPIDLCAEG KHDCEQICVSAPGVFTCDCNQGYTLNKDEKTCTPIDLCAEGK-HDCEQICVSAPGVFTCD CNQGYTLNKDEKTCTPIDLCAEGKHDCEQICVSAPGVFTCDCNQGYTLNKDEKTCTPIDL CAEGKHDCEQICLSAPGV-FTCDCNKGFKLNKDKKTCTNMDLCNTVEHGCEHQCVSTPGS YYCICPEGQL-----------LQEDGKSCGT------C---KSANIDLVL---------- -LIDGSKSVRPQNFELVKKFVNQVVDSLD-VSTHGTRVGLVQYSSRVRTEF-PLNMYHTA DEIKAAVMKVDYMEKGTMTGLALKHMVENSFSEAEGARPASRNIPRIGLVFTD------- --GRSQD----------------------------------------------------- ----------------DITEFA-------------------------------------- ---KKAKEAGITMYAVGV------------------------------------------ --GKAVE-------------------DELREIASE------------------------- --PVEK----------------------------------HFYYTTDFTAISTIAENLKL N------------------------------------------VCPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------SQGEIE------------------------VKDP------------------ -----------CACESLVEF---------------------------------------- ------------------------------------------------------------ QQATMSSLEQ-LTQK--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LSGMTARLEQLEN-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------QLLSRK------------------------------------- ------------------- >XP_040187548.1 matrilin-4 isoform X1 [Rana temporaria] ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------MK--LLYISTLLLVLITQL- KARPPA------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------E--LQLCKTGPMDLIFII---------------- ------------------------------------------------------------ -----------------DSSRSVR------------------------------------ ----------------------------------------------------------PF EFESMRKFMIDMINSLE----IGPSHTRVGVVQ--YSSQVQNVFSLKTYTTK-AQMHKAI NDIIPLAQGTMTGLAIQYTMNVAFTEEEGARPLSQRIPRVAVIVTDGRPQDRVTEVAAQ- -AREAQIEIYAV--GV-QRADVNSLRTMASPPIE-DHVFYVESFDLIQHF---------- ------------------------------------------------------------ -----------------------AIQFQDKLC-------------GVDMCTEMDHGCQHT CVSVPSSYYCKCNPGYKLNADGKTCSIIDMCAQGDHGCEHLCVSSPGSYTCACREGYRLN NDKKTCSPIDLCARGNHGCEQLCVSSPGS------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YTCACRTGYKLNNDKKTCSMIDLCAQG SHGCEQLCIS-------------------------------------------------- ---------------------------------SLGSYTCGCRTGFQLNNDKKTCSMIDY CSYSNHSCQHECVGILNG-YYCRCNEGYTLQSDGKTCLASDMCNVVDHGCEFKCVSTPGS YHCICPEGQE-----------LQADGKTCNK------C---STGYIDLVF---------- -VIDGSKSVRPQNFELVKQFVIKIVDSLD-VSPHGTHVGLVQYSSRVRTEF-SLNQFKSS KDVSNAVRNIEYMEKGTMTGLSLKHMVEHSFSQQEGARP---NVPKIGLVFTD------- --GRSQD----------------------------------------------------- ----------------DISEWA-------------------------------------- ---KRAKDAGITMYAVGV------------------------------------------ --GKAVE-------------------EELNEIASD------------------------- --PVNK----------------------------------HSFYTADFTTINLIAEDLKL N------------------------------------------ICPEE------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------IKGETE------------------------IKNP------------------ -----------CECEHLVNF---------------------------------------- ------------------------------------------------------------ QTNTLTTLGN-LAEK--------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------LAQLTARLDILEH-------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------ELKEKK------------------------------------- ------------------- >KAG6801720.1 fibrillin-2 isoform X1 [Apis mellifera caucasica] MKATSVKRVLGDCPLVQAPQWGRVRERVLKDGTLQTVYSCEPGRRLKGHKILTCTADGWN HPIPKCV-----PHDNRFR-----HFPTDVYL------------GDDPISAAGEERAARD RVRARKRIGELKKRRKAKERRQRMRHGGEKSAVEPPPPALPRAALNETIMSRLDLSCIM- KARRKGFTKAPPVENAYPAKYARRKSVLPPYNRYLVAVYECTEGYVFEDSTTDRLFCSDG AWLGTIPRCVKVEEATLNNVKRCNQDRGGCEHVCEDTQTGVNCSCFDGFRVKGSSCIDID ECAESTAGCAQICHNDPGSFHCECHSGYQLGTDGKSCLDVNECLVNNGHGPCQGGCINLE GSYECNCSDIPGHKLAADNHTCEDIDECSTNNGGCSHVCLNTPGSAFCLCPDGFYLTNDW KTCQDVNECENASKVCTNNTDCENTVG--SFKCVSKPQKMTKVLQDEDYDAEDDEDDDDY DEEEGITEIPEFGKCEDGFRKSKNGECIDIDECSDEGELPSCQHGCVNEPGGYYCTCHLG FKLGEDGVSCQDIDECEDGSRPCSHGCNNTEGSFECTCPTGFTLKEDNLTCARARSCETL STPCSHECRESEDGPICVCPLGYRVHEDEVSCVDTDECAVNPCSHSCVNFEGGFACTCPQ GFQTLEHDKYNCTDVDECANNVHDCEHECVNVQGGYTCNCRSGFALNDDNRTCSDVDECL DGVHRCEQ-----ICVNSIGNYTCSCREGYRISKEGFLDC----VDINECDEGGHGCSHE CSNEEGGFKCGCPPGY-LLGNDSRICQDANECLEGTHQCSHECVNLQGSYACTCPLGMTV SEDKRLCVPLDPCRFANCSHTCERRRDTFECGCPDGFVLHEDGRTCQDFDECLENEHDCS HECANTLGSYECLCPDGLTLLQDGLTCEDPSCPEGLRQDDEGGCRDIDECLERNHECSHI CVNEHATYRCSCLSGWTLSDDGVTCVLSDPCANSS--CSHICLSYASTPVCDCPPGYELA ADAATCEDVDECRDGSANCSFSCTNTDGSYACDCPQGFILGEDGRSCVDVDECARRDHDC PRECVNLEGTYECVCPIGYAFSKTELACVDVDECGTGQHACSHACTNTPGGYNCTCPIGW RLREDSRNCFPSTVHRNCSHAYERDGEETRCGCPEGFELQDDEATCGDVDECAEHPPPCP YRCVNTKGSYRCECPPGLRLRQDRTTCQDIDECVENNNGGCSHDCANTQGSFHCVCPRGY ELIEDGKTCADVDECAVNDNGGCSHDCTNTQGSFHCVCPRGYELIEDGKTCADVDECIVN DNGCSHECANTEGSFYCICPRGYELIEDGKTCADVDECTRKDVHGCSHRCENLDGGYVCS CPDGWIVGRDNRTCTMA--CEAAPHNCSHTCVNVRGGYECECPAGWELSSDGRTCEEVDF CA-GGHGCSHECARVAGGGFQCRCPAGYVLSEDNRSCLDRNECEEGNGGCSHSCVNTDGS YECGCPNGYR-----------LAADRNTCEDVNE---CIEDNGGCSHLCA---------- NIEGGVECACPDNYKLLEDDGKTCVEIDECLIDNGGCTHLCHYENGTVSCFCPPGMILAD DNATCAEENKCYADNGGCS-----HYCSYEDGRVACSCPTDLVLSENGTVCVEENGCSSG NGGCSHDCRYEGGETFCLCPDDMILADDDKLRCVYANKCFVDNGGCSDICSFSNGSVACE CPSGFKLSEGDNATCVDVDECSELLDNCTHRCTNTEGGFECGCNEGFKVSPVEPAFCDDV DECEDARGAGCSHACANLVGSFHCTCPTGYVLENDNKTCRLVDGCKRNNGNCSHHCHHVE EGGEVVHCSCPLGFRLKQDQRTCEDIDECEEFENDVDLGCSHICVNTEGGYYCECPSGYI LLPENKKNCIDMNECLNDRHNCSHDCLNLLGSYVCTCYQGHYLH-SDKSTCLDIDECLER NGGCSHQCTNTIGGHFCSCPTGYELSQDEKTCIDVDECKTDLADCPHE-CVNTLGSWTCT CPDGHALANDSKTCVDVDECKVDNGGCSHACLNVVGGVRCNCPIGLRLDDDGKTCNDVDE CSTDNGGCSDVCVNFVGSYSCRCVNAGLHLHTDAKTCLDVNECEMENGGCSDNCINVRGS YRCECPAGFRLKSDQRTCDDVNECDHDNGGCSHECVNELGGYRCDCPPGHELRNKSRCHP VDPCA--NDNGGCEQTCTARNGTVACGCK-EGFRLDE-NEDP-PRCRDIDECAGSQHGCD QLCVNTVGSFQCSCKQGFEM--------------QN----STCVDIDECATMDCKGYECI NSYGSYRCECDIGHRLEGDHCVDINECAWNNGGCEHDCINTVGSYVCACRPGYIPRRR-- NRNQCQDINECLNHNGGCNGGCVNTAGSYYCTCNGDLVLASDERTCISAESRCRAMEPPL HAEIRCPGHSSGAMDYPVGARCHIQCRRGFRLEGPHTRYCMAGDQWNGKEPICIQASIVT DSRYHSDMPRPFVRCPRDMDVELPARQNTIRVSFPQPKSNMNWWRYVDASPSWAKQLQAD LPAGTTVVTFTAWSPVSNYTSTCRIVIRVRDTENPKVSTCPTSFEVRLSPGERNRLIFWQ EPTFTDNVGVERVYKTREPGQLMYPGIHNVRYIASDAAGNRAECHFSIHVRESEHRRDSE PRYYRRRMLMCPGRSPQPIPSTAYGWQIPSGCYLRYTRIFSGAYAVQNYRGQRQNGYQEA RAAYHQVHPVHGGQGQTQLHSTSYPLGDLAETNNGGRNDAICGRSMHDSGKISIICGSYE MVTFANPTGSIVISYTEDI >XP_039271077.1 tenascin-N-like [Styela clava] MEHRN------------------------------------PGR---------------- ---------------------------SNFY----------------------------- ----------------------------------------HRG----LTFGIIIILAWM- TPQTEA------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------Q--KEECRQRPMDIVFVI---------------- ------------------------------------------------------------ -----------------DGSRSVR------------------------------------ ----------------------------------------------------------PW NFKTVQDAVKDMVDAFE---KIGPEETQIGLVQ--YSSRVRQEFKLNDYYSK-EEVNEAI DGIKYMEMGTMTGRALKFITEYSFTAAYGARSDNPDVLKVAVVITDGRAQDNRTVHFWQK KAKDAGIILFAI--GVGRRISDKDLLLIASEPKE-KHQFYVKNFDLIGSL---------- ------------------------------------------------------------ -----------------------PVMLHEQIC-------------DVDECEQEIDNCQQT CKNTIGSFICGCEDGFVLQDDRASCLLYDPCFEAD--CGYKCEPAPA------------- ---------------------------GG------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------YRCTCPDGY------------------ ------------------------------------------------------------ ----------------------------------------------KLDRDEKGCVAIAP SNLESLTLTDITHTTMRA-------TWSLVSPELEDMIDHYLVRYKKAGDDGETVEVTVN ERAIVLEGLEPGTEYLVSVTAYTADGLKSET------I---KAQNTTLFLGETTLDLFNP TLTTMQAKWEPAGGDLLSQYVLTI------TSPEQNRTFTITTDADT-TEA-PLLEGLEP GQLYEGVVTPMY---GKLAGGPGRDTETTKSLIKPNIRVTDTTLSTVDVEFTGI------ --GMPAD-RYE-----------LTLVDVETGETKYVE----------------------- ---------------VDGSEST-------------------------------AKFYD-- --CTPGKEYTVTVRGYIT------------------------------------------ EGGREFE--SP---------------EGVTEGKTK------HI----------------- --PAPV---------------------------------------VDITSTGLATADVMW T----------ISGY---TPLLFKVS-----------------YCPKN------------ ------------------------------------------------DPENKKHIETED ISTKLTG-------------------------------------LEPG----------IE YEVEVVAV--------------DFDDDKKFTSE--------------PGSDTDATKSLH- APPVM---ATGRTYTTATVKWGEIGMPANTWELRYHP-VGSP------------------ -----------DIVKTLVFD---------------------------------------- ------------------------------------------------------------ GSVNKTILED-LTHD--------------------------------------------- ------------------------------------TEY----------EVVVVGVVIEE GERFES------------------------------------------------------ -PPGSDPFT------------LGALDPPVVTISDPTTSSLNSS---------------W- ----VDN----------------------------------------------------- --------------SP-------------------------------------------- -----------------TIPLTK------------------------------------- -------------------
BMGE Cleaned alignment of selected proteins >sp|O95460|MATN4_HUMAN Matrilin-4 OS=Homo sapiens OX=9606 GN=MATN4 PE=1 SV=3 MRGLLC--PVLLLLLQPWETQLQLGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLCGKDQCAEGGHGCQHQCVNAWAMFHCTCNPGYKLAADNKSCLAIDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEHVSYAPDFGTMTHLLENLRGSICPEEGISAGTECECESLVEFQGRTLGALESLAQLTARLEDLENQLANQK >sp|O95460-2|MATN4_HUMAN Isoform 2 of Matrilin-4 OS=Homo sapiens OX=9606 GN=MATN4 MRGLLC--PVLLLLLQPWETQLQLGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLC-----------------------------------------AIDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEHVSYAPDFGTMTHLLENLRGSICPEEGISAGTECECESLVEFQGRTLGALESLAQLTARLEDLENQLANQK >sp|O95460-3|MATN4_HUMAN Isoform 3 of Matrilin-4 OS=Homo sapiens OX=9606 GN=MATN4 MRGLLC--PVLLLLLQPWETQLQ-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LTGKDQCAEGGHGCQHQCVNAWAMFHCTCNPGYKLAADNKSCLAIDLCAEGTHGCEHHCVNSPGSYFCHCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEHVSYAPDFGTMTHLLENLRGSICPEEGISAGTECECESLVEFQGRTLGALESLAQLTARLEDLENQLANQK >sp|O95460-4|MATN4_HUMAN Isoform 4 of Matrilin-4 OS=Homo sapiens OX=9606 GN=MATN4 MRGLLC--PVLLLLLQPWETQLQLGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLC----------------------------------------------------------------------------------AIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEHVSYAPDFGTMTHLLENLRGSICPEEGISAGTECECESLVEFQGRTLGALESLAQLTARLEDLENQLANQK >tr|Q5NJJ5|Q5NJJ5_DANRE Matrilin-4 OS=Danio rerio OX=7955 GN=matn4 PE=1 SV=1 MTR-VLYVSVLLAVMAATEARPKSEPKCKSGPVDLVFIIDGSRSVRPHEFETMRKFMIDIIHELDIGLAATRIGVVQYSSQVQNVFSLKAFSKTEQMVKAINEIIPLAQGTMTGLAIRYAMNVAFSAEEGARP---NVPHVAVIVTDGRPQDRVAEVAAAARESGIEIYAVARADMTSLRAMASPPFEDHVFLVESFDLIHQFGLQFQDKLCGMDLCLESDHGCEHICESSPGSYQCLCLPGYTLNEDGKTCTPIDLCAEGKHDCEQKCVSVLNGFHCICNEGYTLNEDKKTCTMIDYCSFGNHSCDHHCVSVLNGFFCRCNEGYTLQEDGKTCQSDNLCNTVEHGCEYQCVSTPGSYHCICPEGHVLQDDGKSCGTRTSNIDLVLLIDGSKSVRPQNFELVKQFVNQVVDQLDVSAKGTRVGLVQYSSRVRTEFPLSMYHSKDEIKKAVMNVEYMEKGTMTGLALKHMVENSFSEAEGARPAEKNIPRVGLVFTDGRSQDDIQEWAKKAKEAGITMYAVGVGKAVEDELREIASDHFFYSADFTAISQIAENLKLNVCAAE-SKGDIECACESLVEFQQVTMSTIEQLSAMTKRLEVLEKQLL--- >NP_038620.2 matrilin-4 precursor [Mus musculus] MRGPCCPLSLLLLFLQSWETQLQSGPRCYNGPLDLVFMIDSSRSVRPFEFETMRQFLVGLLRSLDVGLNATRVGVIQYSSQVQSVFPLGAFSRREDMERAIRAVVPLAQGTMTGLAIQYAMNVAFSEAEGARPSEERVPRVLVIVTDGRPQDRVAEVAAQARARGIEIYAVQRADVGSLRTMASPPLDQHVFLVESFDLIQEFGLQFQGRLCGKDLCAELVHGCQHLCVNAPGTFYCACNSGYKLAPDNKNCLALDLCAEGTHGCEHLCVNSVDSYFCRCRAGFALQQDQRSCRAIDYCSFGNHSCQHECVSTLEGPQCRCREGHDLLPDGRSCRVRDFCNDVDHGCEFQCVSEGLSFHCLCPEGRRLQADGKSCDRREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRDLNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEEELREIASEHVSYSPDFSTMTHLLENLKGSICPEEGIGAGTECECESLVEFQGRTLGALESLARLTERLEELENQLASRK >NP_001100009.1 matrilin-4 precursor [Rattus norvegicus] MKGPFCPLPLLLLFLQSWETQLQPGPRCYTGPLDLVFMIDSSRSVRPFEFETMRQFLVGLLHSLDVGLNATRVGVIQYSSQVQSVFPLGAFSNREDMERAIRAVVPLAQGTMTGLAIQYAMNVAFSEAEGARPSEERVPRVLVIVTDGRPQDRVAEVAAQARARGIEIYAVQRADVGSLRAMASPPLDQHVFLVESFDLIQEFGLQFQGRLCGKDLCAELEHGCQHLCVNAPGTFYCACNSGYKLAPDNRNCLAIDLCAEGTHGCEHLCVSSVDSYFCRCRAGFALQQDQRSCRAIDYCSFGNHSCQHECVSTLVGPQCRCREGHDLLPDGRSCQVRDFCNGVDHGCEFQCVSEGLSFHCLCPEGRRLQADGKSCDRREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEVQGARPRDLNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEEELREIASEHVSYSPDFNTMTHLLENLKGSICPEEGISAGTECECESLVEFQGRTLGALESLARLTERLEELENQLASRK >XP_425698.5 matrilin-4 [Gallus gallus] MK--LLLAALLLLILTALEARPKPALKCRTGPLDIVFVIDSSRSVRPFEFETMRRFMIDIIGNLDVGPNATRVGVIQYSSQVQNIFSLKTFFTRAEMERAINSIVPLAQGTMTGLAIQYAMNVAFTVQEGARPPHKKIPRIAIIVTDGRPQDRVSEVAAHARNAGIEIYAVQRADMNSLRAMASPPLEEHVFLVESFELIQQFGKQFQDKLCGVDMCMERDHGCQHSCVSTPGSFYCECHPGYQLNVDGKTCSPIDACADGRHGCEHHCISARGTYSCRCRAGYYLNQDRRSCTMIDYCSFGNHSCQHDCVSIPAGHRCRCRDGFMLQHDGKSCRAIDLCNGVDHGCEFKCVSSEGSFHCVCPEGQQLQADGKTCSKGAGHVDLVMVIDGSKSVRPQNFELVKQFVNRIVDLLEVSPDGTHVGLVQYSSRVRTEFPLNKYHSAEEIKAAVMKMEYMEKGTMTGLALKHMVEHSFSELEGARPLSHNVPRIGLVFTDGRSQDDISEWAQRAKESGIVMFAVGVGKAVEEELRAIASEHFSYSADFTTMTHLVENFKLNICPEE-GRGETECECEALVQFQTNTVAILQSIAQMTARLEALEKQIALKK >XP_009435567.1 matrilin-4 isoform X1 [Pan troglodytes] MRGLLC--LMLLLLLQPWETQLQLGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLPGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLC-----------------------------------------AIDLCAEGTHGCEHHCVNSPGSYFCRCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVVYAVGVGKAVEAELREIASEHVSYAPDFGTMTHLLENLRGSICPEEGISAGTECECESLVEFQGRTLGALESLAQLTARLEDLENQLANQK >XP_005635167.1 matrilin-4 isoform X1 [Canis lupus familiaris] MRGLLCPLPVLLFLLQPWETLSQFGPRCRTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRGLDVGPNATRVGVIQYSSQVQSVFPLGAFSRREDMERAIRALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRIAVIVTDGRPQDRVAEVAAQARARGIEIYAVQRADVGSLRAMASPPLDEHVFLVESFNLIQEFGQQFRGRLCGKDLCAEGRHGCQHQCVSTPGTFRCACNPGYQLAEDNKSCLAIDLCTGGTHGCEHHCISSPGSYFCRCRAGFVLQQDQRSCRAIDHCGFGNHSCQHECVSTFGGPRCRCREGHDLLPDGRSCQARDLCNGVDHGCEFQCVSEGLSYRCLCPEGQQLQADGKSCNHREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWARRAKEEGIVMYAVGVGKAVEEELRQIASEHVSYSPDFGTMTHLLENLRGSICPEEGIGAGTECECESLVEFQGRTLGALEKLAQLTARLEDLENQLATQK >NP_001162037.1 matrilin-4 precursor [Pongo abelii] MRGLLC--PLLLLLLQPWETQLQLGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRSEDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLC-----------------------------------------AIDLCAEGTHGCEHHCVNSPGSYFCRCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPQCHCREGHDLQPDGRSCQVQDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASKHVSYAPDFGTMTHLLENLRGSICPEEGISAGTECECESLVEFQGRTLGALESLAQLTARLEDLENQLANQK >NP_001178240.2 matrilin-4 precursor [Bos taurus] MRGLLYLLPLLLLLLQPWETQLQLGPRCSSGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRAVVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEAHVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVQRADVGSLRAMASPPLNEHVFLVESFDLIQEFGRQFQGRLCTLDLCTEGDHGCEHQCVS-----------------------------------------MPGSYFCRCQAGFVLQQEQRSCRAIDHCSFGNHSCQHDCVSIYGGPQCRCREGYDLLPDGRSCQARDLCNGVDHGCEFQCVSEGFSYRCVCPEGRQLQADGKSCSRREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDNISVWAARAKEEGIVMYAVGVGKAVEEELREIASEHVSYSPDFSTMTHLLENLKGSICPEEGIGAGTECECESLVEFQGRTLGALESLAQLTARLEDLENQLATQK >XP_017206222.1 PREDICTED: matrilin-4 isoform X1 [Oryctolagus cuniculus] MRGLLCPLLVLLLLAQPWEAQPQFGPKCHTGPLDLVFVIDSSRSVRPLEFETMRRFLVGLVRSLDVGPNATRVGVIQYSSQVQSVFPLGAFSRREDMERALRTLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGRQFRGRLCGKAPCAEGRHGCQHQCVNTQGAVRCACNPGYKLAADNKSCLAIDPCAEGTHGCDHHCVSSPGSYFCRCQAGFVLLQDQRSCRAVDPCSLSNHSCQHECVSTLDGPHCRCPDGHDLQPDGRSCRIRDLCNSVDHGCEFQCVSEGLSYRCLCPEGRPLEADGKSCSRREGHVDLVLLVDGSKSVRPQNFELVKRFVTQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAELKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEEELREIASEHVSYSPDFSTMTHLLENLKGSICPEEGVGAGTECDCDSLVEFQGRALGSLESLAQLTARLEDLESLLAGQK >XP_020933255.1 matrilin-4 [Sus scrofa] MRGLLGLLPLLLLLLQPWETQLQFGPRCRTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGPNATRVGVIQYSSQVQSVFPLGAFSRREDMEGAIRALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVAAQARSRGIEIYAVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGQQFQGRLCRKDLCAEGGHGCQHQCVSAPGTFHCACNPGYRLAADNKSCLAINLCAEETHGCEHHCVSSPGSYFCHCRAGFVLQQDQRSCRAIDYCGFGNHSCQHECVNTFGGPRCRCREGHDLLPDGRSCQARDLCNGVDHGCEFQCVSEGLSYRCLCPEGQQLLADGKSCNRREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDVSVWAARAKEEGIVMYAVGVGKAVEEELREIASEHVSYSPDFSTMTHLLENLKGSICPEEGIGAGTECECDSLVEFQGRTLGALESLAQLTARLEELENQLAAQK >XP_010720616.1 matrilin-4 [Meleagris gallopavo] MK--LLLAAFLLLVLTALEARPKPALKCRTGPLDIVFVIDSSRSVRPFEFETMRRFMIDIIGNLDVGPNATRVGVIQYSSQVQNIFSLKTFFTRAEMERAINSIVPLAQGTMTGLAIQYAMNVAFTVQEGARPPHKKIPRIAIIVTDGRPQDRVSEVAAHARNAGIEIYAVQRADMNSLRAMASPPLEEHVFLVESFELIQQFGKQFQDKLCGVDMCMEQDHGCQHSCVSTPSSFYCECHPGYQLNVDGKTCSPIDACADGRHGCEHHCISTRGTYSCRCRAGYHLNQDKRSCTMIDYCSFGNHSCQHDCVSIPAGHRCRCRDGFMLQHDGKSCRAIDLCNGVDHGCEFKCVSSEGSFHCVCPEGQQLHADGKTCNKGAGHVDLVMVIDGSKSVRPQNFELVKQFVNRIVDLLEVSPDGTRVGLVQYSSRVRTEFPLNKYHSAEEIKEAVMKMEYMEKGTMTGLALKHMVEHSFSELEGARPLSHNVPRIGLVFTDGRSQDDISEWAQRAKESGIVMFAVGVGKAVEEELRAIASEHFSYSADFTTMTNLVENFKLNICPEE-GRGETECECEALVQFQTNTVAILQSIAQMTARLEALEKQIALKK >XP_008949583.1 matrilin-4 isoform X1 [Pan paniscus] MRGLLC--LMLLLLLQPWETQLQLGPRCHTGPLDLVFVIDSSRSVRPFEFETMRQFLMGLLPGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLC-----------------------------------------AIDLCAEGTHGCEHHCVNSPGSYFCRCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYRCLCPEGRQLQADGKSCNRREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEHVSYAPDFGTMTHLLENLRGSICPEEGISAGTECECESLVEFQGRTLGALESLAQLTARLEDLENQLANQK >XP_023106971.1 matrilin-4 isoform X1 [Felis catus] MRGLLCPRLMLLLLLQPWESQLQFGPRCRTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRGLDVGPNATRVGVIQYSSQVQSVFRLGAFSRREDMERAIRALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRIAVIVTDGRPQDRVAEVAAQARARGIEIYAVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQGRLCGKDLCVEGGHGCQHQCVSALGTFHCACNPGYQLAEDNKSCLAIDLCAEGTHGCEHHCISSPGSYSCRCRAGFVLQQDQRSCRAIDHCSFGNHSCQHECVSTFRGPRCHCREGHDLLPDGRSCQARDLCNGVDHGCEFQCVSEGLSYRCLCPEGQQLQADGKSCNRREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEEELRQIASEHVSYSPDFGSMTHLLENLRGSICPDSGAGAGQHCCAQFFVGFQPRTDGSLCALRSLVLRISWCP-QIRLKS >XP_014955384.2 matrilin-4 isoform X1 [Ovis aries] MRGLLYMLPLLLLLLQPWETQLQLGPRCSTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVQRADVGSLRAMASPPLNEHVFLVESFDLIQEFGRQFQGRLCRKDLCAQGGHGCQHQCVSALGTFHCACNPGYQLAADNKSCM-----------------------------------------AIDHCSFGNHSCQHDCVSTFGGPQCRCREGYDLLPDRRSCQARDLCNGVDHGCEFQCVSEGFSYHCVCPEGRQLQADGKSCSRREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRELNVPRVGLVFTDGRSQDNISVWAARAKEEGIVMYAVGVGKAVEEELREIASEHVSYSPDFSTMTHLLENLKGSICPEEGIGAGTECECESLVEFQGRTLGTLESLAQLTARLEDLENQLATQK >XP_018872360.1 matrilin-4 isoform X1 [Gorilla gorilla gorilla] MRGLLC--PVLLLLLQPWETQLQLGPRCHTGPLDLVFVIDSSRSVRPFEFETVRQFLMGLLRGLNVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRDLVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEERVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVQRADVGSLRAMASPPLDEHVFLVESFDLIQEFGLQFQSRLC-----------------------------------------AIDLCAEGTHGCEHHCVNSPGSYFCRCQVGFVLQQDQRSCRAIDYCSFGNHSCQHECVSTPGGPRCHCREGHDLQPDGRSCQVRDLCNGVDHGCEFQCVSEGLSYHCLCPEGRQLQADGKSCNRREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDDISVWAARAKEEGIVMYAVGVGKAVEAELREIASEHVSYAPDFGTMTHLLENLRGSICPEEGISAGTECECESLVEFQGRTLGALESLAQLTARLEDLENQLANQK >XP_023811128.1 matrilin-4 [Oryzias latipes] MRP-LRSRVFVLLGLVVLAARPRADQKCKPGPLDLIFLIDSSRSVRPHEFETMRKFMIDILNSLEIGPDSTRVGVVQYSSQVRSEFSLKTHGDLESVVAGIRQIVPLAQGTMTGLAIRYMMNEAFTAEQGDRP---KVPNVAVIVTDGRPQDRVAEVAAEARERGIEIFAVARADMTSLRAMASLPFEDHVFLEESFDLIHQFGLQFQDAFCGLDLCKEMDHGCEHVCENSPGSFHCLCSEGYTLNEDGKTCTAIDLCAEGKHDCEQHCVNMLNGFYCTCKEGHTLNEDERSCTPIDLCAEGKHDCEQVCISAPGVFTCDCRKGFRLNHDKKTCTNMEMCSSVQHGCEHQCVNTPGSYYCVCPEGQLLQDDGKSCGATSANIDLVLLIDGSKSVRPQNFELVKKFVNQVVDSLDVSAHGTRVGLVQYSSRVRTEFPLNMYHTAEDIKAAVMKVEYMEKGTMTGLALKHMLENSFSEAEGARPAARSVPRVGLVFTDGRSQDDISEYAKKAKEAGITMYAVGVGKAVEDELREIASEHFYYTTDFNAISTIADNLKLNVCPEE-SQGEVECACENLVEFQQNTGSSLEQLAAMNTRLVELENQLLSRK >XP_021143581.1 matrilin-4 [Columba livia] MK--LLVAPLLLLLLMTLEARPKPALKCRTGPMDIVFVIDSSRSVRPFEFETMRQFMMDIIGSLDVGPNATRVGVIQYSSQVQNIFSLKTFFTRADMEKAINSIVPLAQGTMTGLAIQYAMNVAFTTQEGARPLHKKIPRIAIIVTDGRPQDRVTEVATQARNAGIEIYAVQRADMNSLRAMASPPLEEHVFLVESFELIQQFGKQFQDKLCGVDMCVEREHGCQHSCISTPGSFYCECNPGYRLNMDGRTCSPIDACADGRHGCQHHCISARGSYSCRCRAGYYLNQDKRSCTMIDYCSFGNHSCQHECVSIPSGHYCRCRSGFTLQPDGRSCRATDLCNGVDHGCEFKCVSTDGSYHCVCPDGQQLQADGKACSKGSGHVDLVMVIDGSKSVRPQNFELVKQFVNRIVDLLEVSPHGTRVGLVQYSSRVRTEFPLNKYHSADEIKKAVMEVEYMEKGTMTGLALKHMVEHSFSELEGARPLSHNVPRIGLVFTDGRSQDDISEWARRAKESGIVMFAVGVGKAVEEELRAIASEHFSYSADFTTMTHLVENFKLNICPEE-SKGETECECEALVQFQTNTVAILQSIAQMTARLEDLEKQIAKKK >XP_017913405.1 PREDICTED: matrilin-4 [Capra hircus] MRGLLYMLPLLLLLLQPWETQLQLGPRCSTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVQRADVGSLRAMASPPLNEHVFLVESFDLIQEFGRQFHGRLCRKDLCAQGGHGCQHQCVSALGTFHCACNPGYQLAADNKSCM-----------------------------------------AIDHCSFGNHSCQHDCVSTFGGPQCRCREGYDLLPDRRSCQARDLCNGVDHGCEFQCVSEGFSYHCVCPEGRQLQADGKSCSRREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRELNVPRVGLVFTDGRSQDNISVWAARAKEEGIVMYAVGVGKAVEEELREIASEHVSYSPDFSTMTHLLENLKGSICPEEGIGAGTECECESLVEFQGRTLGTLESLAQLTARLEDLENQLATQK >XP_043335876.1 matrilin-4 isoform X2 [Cervus canadensis] MRGLLYLLPLLLLLLQPWETQLQFGPRCSTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVQRADVGSLRAMASPPLNEHVFLVESFDLIQEFGRQFQGRLCRKDLCAQGGHGCQHQCVSAPGTFHCACNPGYQLAADNKSCVALDLCTERDRGCGHHCVRIPGSYFCRCQAGFVLRQDQRSCRAIDHCSFGNHSCQHDCVSTFGGPQCRCREGYDLLPDGRSCQARDLCNGVDHGCEFQCVSEGFSYRCMCPEGRQLQADGKSCSRREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDNISVWAARAKEEGIVMYAVGVGKAVEEELREIASEHVSYSPDFSTMTHLLENLKGSICPEEGIGAGTECECESLVEFQGRTLGALESLAQLTARLEDLENQLATQK >XP_043740388.1 matrilin-4 isoform X2 [Cervus elaphus] MRGLLYLLPLLLLLLQPWETQLQFGPRCSTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVQRADVGSLRAMASPPLNEHVFLVESFDLIQEFGRQFQGRLCRKDLCAQGAHGCQHQCVSAPGTFHCACNPGYQLAADNKSCVALDLCTERDRGCGHHCVRIPGSYFCRCRAGFVLRQDQRSCRAIDHCSFGNHSCQHDCVSTFGGPQCRCREGYDLLPDGRSCQARDLCNGVDHGCEFQCVSEGFSYRCMCPEGRQLQADGKSCSRREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDNISVWAARAKEEGIVMYAVGVGKAVEEELREIASEHVSYSPDFSTMTHLLENLKGSICPEEGIGAGTECECESLVEFQGRTLGALESLAQLTARLEDLENQLATQK >KAB0351307.1 hypothetical protein FD754_016164 [Muntiacus muntjak] MRGLLYLLPLLLLLLQPWETQLQFGPRCSTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVQRADVGSLRAMASPPLNEHVFLVESFDLIQEFGRQFQGRLCRKDLCAQGGHGCQHQCVSAPGTFHCACNPGYQLAADNKSCVALDLCTERDRGCGHHCVSIPGSYFCRCRAGFVLRQDQRSCRAIDHCSFGNHSCQHDCVSTFGGPQCRCREGYDLLPDGRSCQARDLCNGVDHGCEFQCVSEGFSYRCMCPEGRQLQADGKSCSRREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDNISVWAARAKEEGIVMYAVGVGKAVEEELREIASEHVSYSPDFSTMTHLLENLKGSICPEEGIGAGTECECESLVEFQGRTLGALESLAQLTARLEDLENQLATQK >KAB0381538.1 hypothetical protein FD755_003455 [Muntiacus reevesi] MRGLLYLLPLLLLLLQPWETQLQFGPRCSTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVQRADVGSLRAMASPPLNEHVFLVESFDLIQEFGRQFQGRLCRKDLCAQGGHGCQHQCVSAPGTFHCACNPGYQLAADNKSCVALDLCTERDRGCGHHCVSIPGSYFCRCRAGFVLRQDQRSCRAIDHCSFGNHSCQHDCVSTFGGPQCRCREGYDLLPDGRNCQARDLCNGVDHGCEFQCVSEGFSYRCMCPEGRQLQADGKSCSRREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDNISVWAARAKEEGIVMYAVGVGKAVEEELREIASEHVSYSPDFSTMTHLLENLKGSICPEEGIGAGTECECESLVEFQGRTLGALESLAQLTARLEDLENQLATQK >KAF4023671.1 hypothetical protein G4228_015599 [Cervus hanglu yarkandensis] MRGLLYLLPLLLLLLQPWETQLQFGPRCSTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVQRADVGSLRAMASPPLNEHVFLVESFDLIQEFGRQFQGRLCRKDLCAQGGHGCQHQCVSAPGTFHCACNPGYQLAADNKSCVALDLCTERDRGCGHHCVRIPGSYFCRCRAGFVLRQDQRSCRAIDHCSFGNHSCQHDCVSTFGGPQCRCREGYDLLPDGRSCQARDLCNGVDHGCEFQCVSEGFSYRCMCPEGRQLQADGKSCSRREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDNISVWAARAKEEGIVMYAVGVGKAVEEELREIASEHVSYSPDFSTMTHLLENLKGSICPEEGIGAGTECECESLVEFQGRTLGALESEASLTSHWPS--------- >XP_018093529.1 matrilin-4 isoform X2 [Xenopus laevis] MK--MFISTLLLISFATLDARPQTVQKCKSGPMDLVFIIDSSRSVRPFEFETMRKFMIDIINPLEVGLSNTRVGVVQYSSQVQNVFSLKTFSNKSDMEKAINEIIPLAQGTMTGLAIQYAMNVAFTEEEGARPLSKNIPRVAIIVTDGRPQDRVTEVAAQARDTGIEIYAVQRADVSSLRTMASHPLDDHVFHVESFDLIQHLSIQFQDKLSCVDMCTEMDHGCQHKCVNIPSSYYCECNEGYKLNADGKTCSLIDLCAQGNHGCEQICVSSPGSYSCACRAGYQLNEDKKTCSMIDYCSYGNHSCQHECVSILNGYYCRCNEGYTLQADGKTCLADDMCNVVDHGCEFKCVSTPGSYYCICPEGQELQADGKTCNKSTGYVDLVLVIDGSKSVRPQNFELVKEFVINIVDSLAISAQGTHIGLVQYSSRVRTEFSLDQYKNAQDIKTAVKNVQYMEKGTMTGLALKHMVEQSFSEAEGARK---NVPKIGLVFTDGRSQDDISEWAKKAKEAGITMYAVGVGKAVEDELNEIASEHSFYTADFSTMNLIAEDLKLNICPEE-IKGTTECDCEHLVSFQTSTITKLESLAQLNARLDDLENELVSKK >XP_006016728.1 matrilin-4 isoform X1 [Alligator sinensis] MK--LLVAPLLLFALTMLEARPKPALKCKTGPLDIVFVIDSSRSVRPFEFETMRRFMIDIIHNLDVGLNATRVGVIQYSSQVQNVFSLKTYFKRADMEKAINSIVPLSQGTMTGLAIQYAMNVAFTTQEGARELHKKIPRVAVIVTDGRPQDRVTEVAAQARDAGIEIYAVQRADMNSLRAMASHPLEQHVFLVESFDLIQQFGKQFQDKLCGVDMCTELDHGCQHTCVSVPGSFYCGCNPGYKLNADGKTCSAIDACADGKHGCEHQCVSARGSYTCRCRLGYSLNDDKKTCTAINYCNFGNHSCQHECVSLVNGYYCRCNDGFTLQADGRSCQATDLCNGVDHGCEFKCVSTSGSYHCICPEGQQLQTDGKTCNKKAGHIDLVLVIDGSKSVRPQNFELVKQFVNQIVDFLDVSPHGTRVGLVQYSSRVRTEFPLNKYKTANDVKAAVMKVEYMEKGTMTGLALKHMIEHSFSEAEGARPLSQNIPRIGLVFTDGRSQDDISEWAMKAKESGIVMFAVGVGKAVEEELREIASEHFSYSADFSTMTHIVDNLKLNICPEE-GKGETECECEALVQFQSNTVAILESLAQMTARLEDLENQIAKKK >XP_006275851.1 PREDICTED: matrilin-4 [Alligator mississippiensis] MK--LLVAPLLLFALTMLEARPKPALKCKTGPLDIVFVIDSSRSVRPFEFETMRRFMIDIIHNLDVGLNATRVGVIQYSSQVQNVFSLKTYFKRADMEKAINSIVPLSQGTMTGLAIQYAMNVAFTTQEGARELHKKIPRVAVIVTDGRPQDRVTEVAAQARDAGIEIYAVQRADMNSLRAMASHPLEQHVFLVESFDLIQQFGKQFQDKLCGVDMCTELDHGCQHICVSVPGSFYCGCNPGYKLNADGKTCSAIDACADGKHGCEHQCVSARGSYTCRCRLGYSLNDDKKTCTAINYCNFGNHSCQHECVSLVNGYYCRCNDGFTLQADGRSCQATDLCNGVDHGCEFKCVSTSGSYHCICPEGQQLQTDGKTCNKKAGHIDLVLVIDGSKSVRPQNFELVKQFVNQIVDFLDVSPHGTRVGLVQYSSRVRTEFPLNKHKTANDVKAAVMKVEYMEKGTMTGLALKHMIEHSFSEAEGARPLSQNIPRIGLVFTDGRSQDDISEWARKAKESGIVMFAVGVGKAVEEELREIASEHFSYSADFSTMTHIVDNLKLNICPEE-GKGETECECEALVQFQSNTVAILESLAQMTARLEDLENQIAKKK >XP_015813978.1 PREDICTED: matrilin-4 isoform X1 [Nothobranchius furzeri] MK--MRLSVLVLLTLAVLTARPKAEQKCKSGPVDLVFLIDSSRSVRPHEFETMRKFMIDILDTLDIGLDTTRVGVVQYSSQVRSEFSLKTHSKLENMVKAINEIIPLAQGTMTGLAIRYLMNEAFSPEQGDRP---EVPNVAVIVTDGRPQDRVAEVAAEAREKGIEIFAVARADMTSLRAMASPPFEDHVFLVERFDLIYQFGLQFQNKLCGLDLCVESDHGCEHLCESSPGSYHCLCLPGYTLNDDGKTCTAIDLCAEGKHNCEQVCVNMGPAFTCDCSEGYRLNEDEKTCSAIDLCAEGKHDCEQMCISTPGAFTCDCNKGFKLNDDKKTCTNMDMCNTVAHGCEHQCVNTPGSFHCICPEGQPLQDDGKSCGTKSAVIDLVLLIDGSKSVRPQNFELVKKFVNQVVDTLDLSAHGTRVGLVQYSSRVRTEFPLNKYHTAEEIKAAVMKVEYMEKGTMTGLALKHMLENSFSEAEGARPASRNIPRVGLVFTDGRSQDDISEYAKKAKEAGITMYAVGVGKAVEEELREIASEHFYYTTDFSAISTIAENLKLNVCPAE-SQGEIECACENLVEFQQATMSSLQQLTSMAARLEQLENQLLSRK >XP_020767141.1 matrilin-4 [Odocoileus virginianus texanus] MRRLLYLLPLLLLLLQPWETQLQFGPRCSTGPLDLVFVIDSSRSVRPFEFETMRQFLVGLLRSLDVGPNATRVGVIQYSSQVQSVFPLRAFSRREDMERAIRALVPLAQGTMTGLAIQYAMNVAFSVAEGARPPEARVPRVAVIVTDGRPQDRVAEVAAQARARGIEIYAVQRADVGSLRAMASPPLNEHVFLVESFDLIQEFGRQFQGRLC-----------------------------------------PLDLCTKRDHSCGHHCISVPGSYFCQCQAGFVLQQDQRSCRAIDHCSFGNHSCQHDCVSTFGGPQCRCREGYDLLPDGRSCQARDLCNGVDHGCEFQCVSEGFSYRCMCPEGRQLQADGKSCSRREGHVDLVLLVDGSKSVRPQNFELVKRFVNQIVDFLDVSPEGTRVGLVQFSSRVRTEFPLGRYGTAAEVKQAVLAVEYMERGTMTGLALRHMVEHSFSEAQGARPRALNVPRVGLVFTDGRSQDNISVWAARAKEEGIVMYAVGVGKAVEEELREIASEHVSYSPDFSTMTHLLENLKGSICPEEGIGAGTECECESLVEFQGRTLGALESLAQLTARLEDLENQLATQK >XP_030275675.1 matrilin-4 isoform X1 [Sparus aurata] MK--MRLRGFILLTLAVLAARPKAEQKCKSGPVDLVFLIDSSRSVRPHEFETMRKFMIDILATLDIGLNATRVGVVQYSSQVRSEFSLKTHAKLETMVKGINEIIPLAQGTMTGLAIKYVMNNAFTAEAGDRP---KVPNVVVIVTDGRPQDRVAEVAAEAREKGIEIYAVARADMTSLRAMASPPFEDHVFLVESFDLIHQFGLQFQDKLCGMDLCLESDHGCEHICESSPGSFHCLCLPGYTLNDDGKTCAAIDLCAEGKHDCEQECVSVLNGFTCDCNQGYTLNKDEKTCTPIDLCAEGKHDCEQICLSAPGVFTCDCNKGFKLNKDKKTCTNMDLCNTVEHGCEHQCVSTPGSYYCICPEGQLLQEDGKSCGTKSANIDLVLLIDGSKSVRPQNFELVKKFVNQVVDSLDVSTHGTRVGLVQYSSRVRTEFPLNMYHTADEIKAAVMKVDYMEKGTMTGLALKHMVENSFSEAEGARPASRNIPRIGLVFTDGRSQDDITEFAKKAKEAGITMYAVGVGKAVEDELREIASEHFYYTTDFTAISTIAENLKLNVCPEE-SQGEIECACESLVEFQQATMSSLEQLSGMTARLEQLENQLLSRK >XP_040187548.1 matrilin-4 isoform X1 [Rana temporaria] MK--LLISTLLLVLITQLKARPPALQLCKTGPMDLIFIIDSSRSVRPFEFESMRKFMIDMINSLEIGPSHTRVGVVQYSSQVQNVFSLKTYTTKAQMHKAINDIIPLAQGTMTGLAIQYTMNVAFTEEEGARPLSQRIPRVAVIVTDGRPQDRVTEVAAQAREAQIEIYAVQRADVNSLRTMASPPIEDHVFYVESFDLIQHFAIQFQDKLCGVDMCTEMDHGCQHTCVSVPSSYYCKCNPGYKLNADGKTCSIIDMCAQGDHGCEHLCVSSPGSYTCACRTGYQLNNDKKTCSMIDYCSYSNHSCQHECVGILNGYYCRCNEGYTLQSDGKTCLASDMCNVVDHGCEFKCVSTPGSYHCICPEGQELQADGKTCNKSTGYIDLVFVIDGSKSVRPQNFELVKQFVIKIVDSLDVSPHGTHVGLVQYSSRVRTEFSLNQFKSSKDVSNAVRNIEYMEKGTMTGLSLKHMVEHSFSQQEGARP---NVPKIGLVFTDGRSQDDISEWAKRAKDAGITMYAVGVGKAVEEELNEIASDHSFYTADFTTINLIAEDLKLNICPEE-IKGETECECEHLVNFQTNTLTTLGNLAQLTARLDILEHELKEKK >KAG6801720.1 fibrillin-2 isoform X1 [Apis mellifera caucasica] PRAALNTIMSRLDLSCIMKARRKGSFKCVSKPQKMTKVLDGSRPCSPQGFQTLEHDKYNCTDVDEVHDCEHECVNVQYTCNCRSGFALNDDNRTSDVDECLDGVHRCEQ-----ICVNSIGNYTCSCREGYRISKEGFLDC----VDINECDEGGHGCSHSNEEGGFKCGCLLGNDSRICQDANECLETHQCSHECVNLQGSYGLTCEDPSCDIDECLERNHECSHICVNEHATYRCSCLSGWTLSDDGVTCVLSDPCANSS--CSHSCTNTDGSFHCVCPRGYELSSDGRTCEEVDFCA-GGHGCSHECARVAGGFQCRCPAGYVLSEDNRSCLDRNECEEGNGGCSHSCVNTDGSYECGCPNGYRLAADRNTCEDNGGCSHLCAIEGGVECACPDNYKLLEDDGKTCVEIDELIDNGGCTHLCHYENGTVSCFPPGMILADDNATCAEENKCYADNGGCS-----HYCSYEDGRVACSCPTDLVLSENGTVCVEGCSHDDVDECSEDARGAGCSHACANLGEVVHDECEEFENDHYLH-SDKSTCLDIDECLERNDCPHENDNGGCECSCKQGFEMNRNQCQDINETCRIVIRVRDTENQLHSTS >XP_039271077.1 tenascin-N-like [Styela clava] HRG---LTFGIIIILAWMTPQTEAKEECRQRPMDIVFVIDGSRSVRPWNFKTVQDAVKDMVDAFEIGPEETQIGLVQYSSRVRQEFKLNDYYSKEEVNEAIDGIKYMEMGTMTGRALKFITEYSFTAAYGARSDNPDVLKVAVVITDGRAQDNRTVHFWQAKDAGIILFAIRRISDKDLLLIASEPKEKHQFYVKNFDLIGSLPVMLHEQICDVDECEQEIDNCQQTCKNTIGSFICGCEDGFVLQDDRASCLLYDPCFEAD--CGY------GGYRCTCPDGYKLDRDEKGCVAIAPSNLESLTLTDITHTTMRA------TWSLVSPELEDMIDHYLVRYKKAGDDGETVEVTVNERAIVLEGLEYTADGLKSETKAQNTTLFLLTTMQAKWEPAGGDLLSQYVLTI-----TSPEQNRTFTITTDADT-TEAPLLEGLEPGQLYEGVVTPMY---GKLAGGPGRDTETTKSLIKPNIRVTDTTLSTVDVEFTGGMPADDGSESTTPGKEYTVTVRGYITGREFEEGVTEGKTK-----VDITSTGLATADVMWTYCPKN-ATGRTYDIVKTLVFDGSVNKTILEDLGALDPPVVTISDTIPLTK
PhyML tree of selected proteins
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)