PBID | Uniprot | Name | Gene | Alternative | Organism | Uniprot Description |
PB0184 | P11047 | Laminin subunit gamma-1 | LAMC1 | LAMB2 | Homo_sapiens | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
Domains | Gene Ontology |
PF00052 (Laminin_B) PF00053 (10_Laminin_EGF) PF00055 (Laminin_N) |
GO:0035633 (acts upstream of or within) maintenance of blood-brain barrier
GO:0005201 (enables) extracellular matrix structural constituent GO:0030023 (enables) extracellular matrix constituent conferring elasticity GO:0007155 (involved in) cell adhesion GO:0007492 (involved in) endoderm development GO:0009887 (involved in) animal organ morphogenesis GO:0009888 (involved in) tissue development GO:0016477 (involved in) cell migration GO:0022617 (involved in) extracellular matrix disassembly GO:0031581 (involved in) hemidesmosome assembly GO:0034446 (involved in) substrate adhesion-dependent cell spreading GO:0045785 (involved in) positive regulation of cell adhesion GO:0050679 (involved in) positive regulation of epithelial cell proliferation GO:0051149 (involved in) positive regulation of muscle cell differentiation GO:0065003 (involved in) protein-containing complex assembly GO:0110011 (involved in) regulation of basement membrane organization GO:2001046 (involved in) positive regulation of integrin-mediated signaling pathway GO:0005576 (located in) extracellular region GO:0005604 (located in) basement membrane GO:0005615 (located in) extracellular space GO:0005788 (located in) endoplasmic reticulum lumen GO:0031012 (located in) extracellular matrix GO:0062023 (located in) collagen-containing extracellular matrix GO:0070062 (located in) extracellular exosome GO:0098637 (located in) protein complex involved in cell-matrix adhesion GO:0005606 (part of) laminin-1 complex GO:0043259 (part of) laminin-10 complex GO:0043260 (part of) laminin-11 complex |
External Links | Description |
Intact | Open source database system and analysis tools for molecular interaction data. |
Protein Atlas | An open access resource for human proteins |
InterPro (new pfam) | InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. |