PB0180

DATABASE

Click here to access PB0180 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0180	Q9UBM4	Opticin	OPTC	OPT	Homo_sapiens	May be involved in collagen fiber organization via regulation of other members of the small leucine-rich repeat proteoglycan superfamily (By similarity).

Domains	Gene Ontology
PF13855 (LRR_8)	GO:0005201 (enables) extracellular matrix structural constituent GO:0030199 (involved in) collagen fibril organization GO:0005576 (located in) extracellular region GO:0031012 (located in) extracellular matrix

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|Q9UBM4|OPT_HUMAN Opticin OS=Homo sapiens OX=9606 GN=OPTC PE=1 SV=1 MRLLAFLSLLALVLQETGTASLPRKERKRREEQMPREGDSFEVLPLRNDVLNPDNYGEVI DLSNYEELTDYGDQLPEVKVTSLAPATSISPAKSTTAPGTPSSNPTMTRPTTAGLLLSSQ PNHGLPTCLVCVCLGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKLK RIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALPVLPSGIEFLDVRLNRLQSSGIQP AAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHKHTRRQ LEDIRLDGNPINLSLFPSAYFCLPRLPIGRFT >tr|Q15JE7|Q15JE7_DANRE Opticin OS=Danio rerio OX=7955 GN=optc PE=1 SV=1 MVIQRQTSKMLLYLVWILLGFSLGAPPTDLDLEAFGLENYDDPDSWDLHYNYDDEHEEVE TVAPPTALTPPPAVVVPENYVEEMTLPPRPTKSPVPSTLDFKAPGLFGPDTGLGMPTCLL CVCISGSVYCDDSDLTHIPPLPKETTHFYARFNKITEIKAADFINLNQLKRIDLSGNQIG KVNEDAFRSLLQLQDLMMADNNIQALPELPASLKHIDIRNNKLRSSGMHAEAFKEMKELQ FLYLSHNKLDYIPVPLPESLRVLHLQNNNIQSITQDTFCNSHDKNYIRKALEDIRLDGNP VDINLYPQAYFCLPRLPVGTPV
Selected proteins from model organisms >sp|Q9UBM4|OPT_HUMAN Opticin OS=Homo sapiens OX=9606 GN=OPTC PE=1 SV=1 MRLLAFLSLLALVLQETGTASLPRKERKRREEQMPREGDSFEVLPLRNDVLNPDNYGEVI DLSNYEELTDYGDQLPEVKVTSLAPATSISPAKSTTAPGTPSSNPTMTRPTTAGLLLSSQ PNHGLPTCLVCVCLGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKLK RIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALPVLPSGIEFLDVRLNRLQSSGIQP AAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLIETMQRDVFCDPEEHKHTRRQ LEDIRLDGNPINLSLFPSAYFCLPRLPIGRFT >tr|Q15JE7|Q15JE7_DANRE Opticin OS=Danio rerio OX=7955 GN=optc PE=1 SV=1 MVIQRQTSKMLLYLVWILLGFSLGAPPTDLDLEAFGLENYDDPDSWDLHYNYDDEHEEVE TVAPPTALTPPPAVVVPENYVEEMTLPPRPTKSPVPSTLDFKAPGLFGPDTGLGMPTCLL CVCISGSVYCDDSDLTHIPPLPKETTHFYARFNKITEIKAADFINLNQLKRIDLSGNQIG KVNEDAFRSLLQLQDLMMADNNIQALPELPASLKHIDIRNNKLRSSGMHAEAFKEMKELQ FLYLSHNKLDYIPVPLPESLRVLHLQNNNIQSITQDTFCNSHDKNYIRKALEDIRLDGNP VDINLYPQAYFCLPRLPVGTPV >NP_473417.2 opticin isoform 1 [Mus musculus] MRGCLAVPCSDRQSSSPPEAPWKLLSQTEPKASKRMYLRGIQPFPLLPLPQNLMKFLAFLSLLSLVLQKA ETASLLGEREREEQSPEEGDTYASLYVGNHTLSIEDYNEVIDLSNYEELADYGDQIPEAKISNLTLPTRT SPTSTVAQKTLSPNLTMAVPTTTGLLNSQSSHGLPTCLVCVCLGSSVYCDDADLENIPPLPQMTTYLYAR FNHISHIQAGDFKGLTKLRRIDLSGNSISSIHNDALRLLPALQDLILPENQLAALPVLPSGIEFLDVRLN RLQSSGIQPEAFVALKKLQFLYLANNMLDSIPGPLPLSLRSLHLQNNMIETMESDTFCDTGEHRHERRQL EDIRLDGNPINLSLFPEAYFCLPRLPVGHFT >XP_038946639.1 opticin isoform X1 [Rattus norvegicus] MGNLIRHMDPWANYLSSPWPINEGVSSCPLVWQAVIIPIRVFVSLEAAGPDGTKTSKRMYVEWIQPFPLL PFPQNLMKFLTFLSLLTLVLQEAGTASLLGEREREEKSPEEADTYASLHVGNYSLSLEDYSEVIDLSSYE ELADYGDQIPEAKTSSPTLPTRTSPTSPVVPRTLPSRLTMAGPTTTGLLNSQSSHGLPTCLVCVCLGSSV YCDDANLENIPPLPQMTTYLYARFNHISHIQAGDFKGMTKLRRIDLSSNSISSIHNDALRLLPALQDLIL PENQLAALPVLPSGLEFLDVRLNRLQSSGIQPEAFVTLEKLQFLYLADNLLDSIPGPLPLSLRSLHLQSS SVHSRDLFHALHTHLPTQNSRRTMKGRGGRGGGRGTEAGMEGRVGRGRVISVLEPGLSDW >NP_989804.1 opticin precursor [Gallus gallus] MALGHRMQTLAWVGIASLCLGAAWAVPAKKERKKVEKLKPDLVLYENLDLDNYDVTLDNYGDIMDLNNYE ELYDYGDLAPKIEVGTLAPRPKDRESLPELVTAAPTPKLQPPDTTNPIRPAPPGPGTAQGVPSCLPCLCI RTSVYCDDTDLEHIPPLPPDTTYLYARFNRISAIRAGDFMGLKKLKRIDLTSNSISWADVDAFRFLPSLQ ELILPENRLTALPELPRSIIRLDARLNRIPSAGLRPEAFQDLTQLQFLHLSDNQLDYIPAPLPESLRSLH LQNNNIQTMHEDTFCNSQDQSHVRRALEDIRLDGNPINLSLFPNAYFCLPRLPTGHFL >NP_999173.1 opticin precursor [Sus scrofa] MKLLALLSLLALMLQEAGTASLPEKERERGEDRLHRESDSSTALHLGDYTLSPDSHDGVLDLSNYEELMD YGDQLPKVKGASLASPTRASSTQSMKPPRTPPSSPTVARPTALSPPGSPTSHAPGLPTCLVCVCLGSSVY CDDTDLENIPPLPQTTTYLYARFNRINHIRAGDFKGLTKLKRIDLSSNFISSIDDDALLLLPDLQDLILI ENQLAALPTLPTAIEVLDVRLNRLRSSGIQPGAFRALEKLQFLYLADNLLDSIPGPLPLSLRSLHLQNNM IETLQRDTFCDPEEHKHTRRQLEDIRLDGNPINLSLFPSAYFCLPRLPIGRFT >NP_001003056.1 opticin precursor [Canis lupus familiaris] MKLPAFLSLLALVLLEAGTASLPKERKRRDEMHGEGDSYVVLGNYVLGPDNYDEVIDLSDYEGLMDYGDQ LPEAKVTNLAPPTGISSAQSTMTPRTLSLKPTMIRPTELGVLGSPNSHGLPTCLICVCLGSSVYCDDADL ENIPPLPKTTTYLYARFNRIRRIRAGDFKGLTKLKRIDLSSNSISSIDDDALRLLPALQDLILPENQLAA LPALPPAIEVLDARHNQLQSSGIQPEALRALEKLQFLYLADNLLDSIPGPLPPSLRSLHLQNNLIETMQT DAFCDPEEHKHSRRWLEDIRLDGNPINLGLFPSAYFCLPRLPTGHCC >NP_991339.1 opticin precursor [Bos taurus] MKLLALLSLLILMLQEARTASLSEEREGDPYAILHLGDYVLSLDNYDEVIDPSNYDELIDYGDQLPQVKG TSLASLTRTRFTQSTEAARTLPSNPTTARPPTLGLLAAPANHGLPTCLICVCLGSSVYCDDADLENIPPL PQTTAYLYARFNRISHIRAGDFKGLTKLKRIDLSGNSISSIDDKALRLLPALRDLILPENKLVALPTLPT SIEVLDVRMNRLQSSGIQPEAFRALEKLQFLYLADNLLDAIPPSLPLSLRSLHLQNNMIETMQRDAFCDA EEHRHTRRPLEDIRLDGNPINLSLFPSAYFCLPRLPTGRFV >XP_016791796.1 opticin [Pan troglodytes] MRLLAFLSLLALVLQETGTASLPRKERKRREEQMPREGDSFEVLPLRNDVLNPDNYGEVIDLSNYEELTD YGDQLPEVKMTSLAPATSISPTKSTTAPGTPSSNPTMTRPTTAGLLLSSQPNHGLPTCLVCVCLGSSVYC DDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLLLPE NQLEALPVLPSGIEFLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLI ETMQRDVFCDPEEHKHTRRQLEDIRLDGNPINLSLFPSAYFCLPRLPIGRFT >XP_017203333.1 PREDICTED: opticin [Oryctolagus cuniculus] MRLPAFLSLLALVLQEGDPHTALPLDDYGLSPDDYGEVLDLGNYEEPTDYGEQPLEVKATSPAPPPTRGS PIQSAKALRTPSSSPTVPGPPTNHSLPTCLVCVCLGSSVYCDDADLESIPPLPKTTTYLYARFNRIRRVR AGDFQGLAKLKRIDLSSNVISYIESDALRALPALQDLLLPENQLAALPALPSSVQLLDARLNRLQSSGIQ PGAFRALEKLQFLYLADNLLDSVPGPLPLSLRSLHLQNNAIGTLRGDEFCDAEEHRHTRRPLEDVRLDGN PVNLSLFPDAYFCLPRLPTGRMV >XP_002809624.1 opticin [Pongo abelii] MRLLAFLSLLALVLQETGTASLPRKERKRREEQMPREGDSFEVLPLRNDVLNPDNYGEVIDLSNYEELTD YGDQLPEVKVTSLAPATSINPAKSTTAPGTPSSNPTMTRPTTAGLLLSSQPNHGLPTCLVCVCLGSSVYC DDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPE NKLEALPVLPSGIEILDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLI ETMQRDVFCDPEEHKHTRRQLEDIRLDGNPINLSLFPSAYFCLPRLPIGRFT >XP_003203890.1 opticin [Meleagris gallopavo] MALGHRMKTLAWVGIASLCLGATWAVPAKKERKKVEKPKPDLVLNENLDLDNYDMTLDSYGDIMDLNNYE ELYDYGDLAPKVEVGTLAPRPKDHGALPELGTAAPTPKLKPLATTNPTHPAPLGLNTAQGLPSCLRCLCI RTSVYCDDTDLEHIPPLPPDTTYLYARFNRIGAIRAGDFMGLKKLKRIDLTSNSISWADVDAFRLLPSLQ ELILPENRLTALPELPRSIVRLDARLNRIPSAGLRPEAFQDLTQLQFLHLSDNQLDYIPAPLPESLRSLH LQNNNIQTMHEDTFCNSQDQSHIRRALEDIRLDGNPINLSLFPNAYFCLPRLPTGRFF >XP_003823034.1 opticin isoform X1 [Pan paniscus] MRLLAFLSLLALVLQETGTASLPRKERKRREEQMPREGDSFEVLPLRNDVLNPDNYGEVIDLSNYEELTD YGDQLPEVKMTSLAPATSISPAKSTTAPGTPSSNPTMTRPTTAGLLLSSQPNHGLPTCLVCVCLGSSVYC DDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPE NQLEALPVLPSGIEFLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRSVHLQNNLI ETMQRDVFCDPEEHKHTRRQLEDIRLDGNPINLSLFPSAYFCLPRLPIGRFT >XP_006942942.2 opticin isoform X1 [Felis catus] MGDPLSKEKGEQLDTSKRRSLIGHTLASASTPLSTLAHCRRPFQQSPYFSGGCEALFLRKQHCVGVPMKI LAFQILLALVLLEAGTASPPKGRKRRDPTNEEGDSYAVLNLGNYVPDLDNYDEVIDLSDYEGLMDYGDQL PEVKAGSSLGPPTRIGSTQSTVNPRTLSSKPTMTKPTMLGLPGSPSSHAEPGLPTCLVCVCLGSSVYCDD ADLESIPPLPKTTTYLYARFNRISRIRAGDFKGLTKLKKIDLSSNSISSIDDDALRLLPALRDLILPENQ LAALPVLPAGIEVLDVRLNRLQSSGIQPEAFRGLERLQFLYLADNLLDSIPGPLPPSLRSLHLQNNMIET MQKDAFCDTEEHKHSRRRLEDIRLDGNPINLGFFPSAYFCLPRLPTGRCC >XP_027831905.1 opticin [Ovis aries] MKLLALLSLLILMLQEAGTAPLSKEERGEEQPYGEGDSYAILHLGDYVLSLDNYEEVIDPSNYDELTDYG DQLPQVKGTSLASLTRTRFTQSTEAARTLPSNPTTARPPTLGLLAAPANHGLPTCLICVCLGSSVYCDDA DLENIPPLPQTTAYLYARFNRISHIRAGDFKGLTKLKRIDLSGNSISSIDDKALRLLPALRDLILSENKL VALPALPTSIEVLDVRMNRLQSSGIQPEAFRALEKLQFLYLADNLLDAIPWPLPLSLRSLHLQNNMIETM QRDAFCDAEEHRYTRRQLEDIRLDGNPINLSRFPSAYFCLPRLPTGRFV >XP_018884560.1 opticin [Gorilla gorilla gorilla] MRLLAFLSLLALVLQETGTASLPRKERKRREEQMPREGDSFEVLPLRNDVLNPDNYGEVIDLSNYEELTD YGDQLPEVKVTSLAPATSISPAKSTTAPGTPSSNPTMTRPTTAGLLLSSQPNHGLPTCLVCVCLGSSVYC DDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPE NQLEALPVLPSGIEFLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGPLPLSLRAVHLQNNLI ETMQRDVFCDPEEHKHTRRQLEDIRLDGNPINLSLFPSAYFCLPRLPIGRFT >XP_021154000.1 opticin [Columba livia] MWALAWLGIASLCLGTAWAVPAKERRKAEKPKAHLALYENLDLDNYDLTLDNYGEILDLSNYEELYDYGD LAPKIEVGTLAPRPKDPAAPPDLGTTAETPKLQLLSTAGPVPPAPIPVQALPSCQLCLCIGTSVYCDDAD LEHIPPLPPETTYLYARFNRIGTIQASDFMGLKKLKLIDLSSNSITRADADAFRLLPSLQELILPENRLT ALPELPRSIVRLDARLNSIPSTGLRPDAFRDLKQLQFLHLSDNQLDYIPAPLPESLRSLHLQNNNIQTMH EDTFCDSQDHSQVRRALEDIRLDGNPINLSLFPNAYFCLPRLPTGRFS >KAB0342281.1 hypothetical protein FD754_019207 [Muntiacus muntjak] MKLLALLSLLILMLQEAGTASLSKEEREEDQPYGEGDSYAILHLGDYVLSLDNYDEVIDPSNYDELTDYRDQLPQVKGTG LASLTRTRFTQSTEVARTLPSNPTMARPPTLGLLAAPANHGLPTCLICVCLGSSVYCDDTDLENIPPLPQTTAYLYARFN RISHIRAGDFKGLTKLKRIDLSGNSISSIDDKALRLLPALRDLILPENKLAALPVLPTSIEVLDVRMNRLQSSGIQPEAF RALEKLQFLYLADNLLDAIPRSLPLSLRSLHLQNNMIETMQSDVFCDAKEHRHTRRQLEDIRLDGNPINLSLFPSAYFCL PRLPTGRFV >KAB0376678.1 hypothetical protein FD755_011122 [Muntiacus reevesi] MKLLALLSLLILMLQEAGTASLSKEKREGDQPYGEGDSYAVLHLGDYVLSLDNYDEVIDPSNYDELTDYRDQLPQVKGTG LASLTRTRFTQSTEVARTLPSNPTMARPPTLGLLAAPANHGLPTCLICVCLGSSVYCDDTDLENIPPLPQTTAYLYARFN RISHIRAGDFKGLTKLKRIDLSGNSISSIDDKALRLLPALRDLILPENKLAALPVLPTSIEVLDVRMNRLQSSGIQPEAF RALEKLQFLYLADNLLDAIPRSLPLSLRSLHLQNNMIETMQSDVFCDAEEHRHTRRQLEDVRLDGNPINLSLFPSAYFCL PRLPTGRFV >KAF4018212.1 hypothetical protein G4228_010223 [Cervus hanglu yarkandensis] MKLLALLSLLILMLQEAGTASLSKEEREEDQPYGEGDSYAVLHLGDYVLSLDNYDEVIDPSNYDELTDYGDQLPQVKGTG LASLTRTRFTQSTEVARTLPSNPTMGRPPTLGLLAAPTDLGLPTCLICVCLGSSVYCDDTDLENIPPLPQTTAYLYARFN RISHIRAGDFKGLTKLKRIDLSGNSISSIDDKALRLLPALRDLILPENKLAALPALPTSIEVLDVRMNRLQSSGIQPEAF RALEKLQFLYLADNLLDAIPRSLPLSLRSLHLQNNMIETMQSDVFCDAEEHRHTRRQLEDVRLDGNPINLSLFPSAYFCL PRLPTGRFV >XP_043341198.1 opticin [Cervus canadensis] MKLLALLSLLILMLQEAGTASLSKEEREEDQPYGEGDSYAVLHLGDYVLSLDNYDEVIDPSNYDKLTDYGDQLPQVKGTG LASLTRTRFTQSTEVARTLPSNPTMGRPPTLGLLAAPTDLGLPTCLICVCLGSSVYCDDTDLENIPPLPQTTAYLYARFN RISHIRAGDFKGLTKLKRIDLSGNSISSIDDKALRLLPALRDLILPENKLAALPALPTSIEVLDVRMNRLQSSGIQPEAF RALEKLQFLYLADNLLDAIPRSLPLSLRSLHLQNNMIETMQSDVFCDAEEHRHTRRQLEDVRLDGNPINLSLFPSAYFCL PRLPTGRFV >OWK08495.1 OPTC [Cervus elaphus hippelaphus] MKLLALLSLLILMLQEAGTASLSKEEREEDQPYGEGDSYAVLHLGDYVLSLDNYDEVIDPSNYDKLTDYGDQLPQVKGTG LASLTRTRFTQSTEVARTLPSNPTMGRPPTLGLLAAPTDLGLPTCLICVCLGSSVYCDDTELENIPPLPQTTAYLYARFN RISHIRAGDFKGLTKLKRIDLSGNSISSIDDKALRLLPALRDLILPENKLTALPMLPTSIEVLDVRMNRLQSSGIQPEAF RALEKLQFLYLADNLLDAIPRSLPLSLRSLHLQVSGCSGNKGVERHRRWRSDCREPPSAVVGLRH >XP_018104794.1 opticin [Xenopus laevis] MYLFIALCVSGIALCSAPPSPGASRNNKEKHRSGENIKLVDYNINYEESIDIRKYEELHDYYDHEPKEVHTLTPLNKKSG LLTNQGTENPITLPSIPKPSEHSLFGSMTEQGLPICLVCACIGTSVYCDDVDLNGIPPLPKDTAYLYARFNRITRINNND FKGLNKLKRVDLSSNFLSKIDDDAIHFLPSLQELILSENQLKALPELPSSLTRLDVQYNQLQSSGIQTDAFKDLTSLEYL YLSNNKLDYIPVPLPYSLRSLHLQNNNIQTMNLETFCESRDLTFIRRNLEDIRMDDNPINLSKFVHGYFCLVRLPTGSYY >XP_030296407.1 epiphycan isoform X3 [Sparus aurata] MRMLVRLVLGLLVLKAVVAGPRFSRQVDLDSYDSANYDVDLDNLNSENQDIYDYDDGLTIDDPQIEIGTLAPPDYNYPVP EASLEEQEQEEEEEEEEMPLKPQLIPQGSGGSGVLMGPDTQKGMPTCLLCTCLGGSVYCDDLKLDSVPPLPKDTTHFYAR YNRITKINKSDFAFLNKLKRIDLTANEITSVDDRAFMALPELEELVIRENHISQLPALPETMTLIDASHNNIGTKGIHNE AFKDMTSLLYLYLTDNHVDYIPVPLPDSLRSLHLQRNNIQMMHEDTFCNLKDFNYIRNALEDIRLDGNPINLSRTPQAYI CLPRIPIGDLI >XP_015815457.1 PREDICTED: dentin sialophosphoprotein-like [Nothobranchius furzeri] MRMLVRLVLGLFVLKAAIASPRFSRQVDLDTYDLANYDEEEDNFDLDNGESYDYDEELTTDESETETETPNELDYNHPPE DLEEEKPEEEEDVQQEKGGEEENQEEKEEEDNHEEEYNQGEENEEEELPLTPQLIPQGSGGSGVLMGPDTQKEVELRRVP VDTLHVSGDFGGSAGSGASGASGASGASGASGSGGSGDILVSGASGESGEIIMMSGASEELFSSGGPEELLSGDILISGD LSGSGVTSGSGVSGFSGDIPSGESEFVTELPVGSGGSGDPSGSGFSGDILISGASGISGASGISGASGISGVSGDSFESG QSGITFITEEEERPLVPEIIPQEASGGSGEISGVSGTSGASGDIGVSGGLEVSGTSGTSGVSASGDIEVPEVNLLPEPEE EEELLPTTPEPSQEVQTSIEETMTSGDPEQPEEEVVDAQGMPVCLLCTCLGGSVYCDDLKLDSVPPLPKDTTHFYARYNK ITKINKSDFANMNKLKRIDLTANEITAIDDKAFMGLPALEQLIIRENHVSQLPALPETMTLIDGSHNNIGSRGIHKEAFK DMTSLQFLYLTDNNIDYIPVPLPDSLRSIHLQRNNIQMMHEDTFCNLNDFNYIRNALEDIRLDGNPINLSKTPQAYICLP RIPVGNLV >XP_004083110.1 aggrecan core protein [Oryzias latipes] MRMFVRLVLGLFVLKAAVASPRFSRQANLDIYDDANYDEELNNVESEDTYDYEDGLTIDEPEIEIETMALPDYTFPEEEK PEEGEEEELTLRPQPIPQGSGGSGVLMGPETQKEVELRQEPVDILHASGDLGGSGSGSGTSGASGASGSGESGDLLISGD IILISGASETLISSEGSGEFLISEKTDFTIPWHTSGSGFESSPSGASGDLTSGHSGISIEIPFGSGESGESGESGDLSGI SPDPSISGASGSSGVSGDPAESGDLGITLISGDEKPFVISKHEPQEASVASGEISGVSSADTEISGTSGVSGVSTSGDDE EPVTVIIETKEEERVLSTTPETPQEGATSIEETDSSGLPEPFEPKEPDEPKIDISGMPTCLLCTCLGTSVYCDDLKLDSV PPLPKETTHFYARYNKITKINKSDFAFMNKLKRVDLTANEITAIDGTAFIGLPELEELVVRQNHLTQLPALPETMTLIDA SHNSIGSKGIHKEAFKDMTGLLFLYLTDNNIDYIPVPLPESLRSLHLQRNNIQMMHEDTFCNLNDFNYIRNALEDIRLDG NPINLSKTPQAYVCLPRIPIGNLI >XP_040200080.1 epiphycan [Rana temporaria] MKTLANIFLGLLIIKAVVSAPPTDSVNYDTAAYEVDLLYNLYDYDENTNIDQGEIEIGTVLPVVNRPILSPEPVQEEIEE EEESTPKLIDGSSPQGPLSPGVPEASGGVSTCILCGCIRTTVYCDDHNLDAVPPLPKDTTHVYLRFNRISKINKNDFSYL SKLQKIDLTSNIISDIDEDAFRSLSQLDELILLDNNIRQLPELPHSVSFLDVSKNRLGRKGIKQEAFKDLNDLRLLYLNN NNLDHIPIPLPDSLQALHLQDNNIQEMHEDTFCNMKDFTYARRSLEDIRLDGNPINLSKTPQAFMCLPRIPVGRLV >XP_005690430.1 PREDICTED: opticin [Capra hircus] MKLPALLSLLILMLQEAGTASLSKEERGEEQPYGEGDSYAILHLGDYVLSLDNYEEVIDPSNYDELTDYG DQLPQVKGTSLASLTRTRFTQSTEAARTLPSNPTTARPPTLGLLAAPANHGLPTCLICVCLGSSVYCDDA DLENIPPLPQTTAYLYARFNRISHIRAGDFKGLTKLKRIDLSGNSISAIDDKALRLLPALRDLILPENQL VALPALPTSIEVLDVRMNRLQSSGIQPEAFRALEKLQFLYLADNLLDAIPRPLPLSLRSLHLQNNMIETM QRDAFCDAEEHRYTRRQLEDIRLDGNPINLSLFPSAYFCLPRLPTGRFV >XP_006025086.1 opticin [Alligator sinensis] MPSAVLLGMITLALAALALAVPLGEGKKTEKPSTDLTIYESLNLDNYDLSLNNYGDIIDLSNYDELYDYG DLAPKIEVGTLAPPAKTPEGMPSTRAVPTATPRKELPMSTTAKPVGPGLLGFITEQGLSTCLVCVCIGTS VYCDDAGLEHIPALPLETMYLYARFNSIGQIRARDFAGLKKLKRIDLTSNYISSVEEGSFRQLTSLQELI LPENRLTVLPDLPSSIIRLDARFNRIQSSGLRPEAFRELKKLQFLHLSDNELDYIPAPLPESLRSLHLQN NNIQTMHQDTFCDSQDLTHIRRALEDIRLDGNPINLSLFPSAYFCLPRLPTGRFY >XP_019347037.1 PREDICTED: opticin [Alligator mississippiensis] MRVLESMGWECVHALAHMHRMPSVVLLGMITLMLAALALAVPLGEGKKTEKPSADLTIYESLNLDSYDLS LNNYGDIIDLSNYDELYDYGDLAPKIEVGTLAPPAKTPEGMPSTRAVPTAAPRKQPPMPTTAKPVGPGLL GFITEQGLSTCLVCVCIGTSVYCDDAGLEHIPALPLETMYLYARFNSIGQIRARDFAGLKKLKRIDLTSN YISSVEEGSFRQLTSLQELILPENRLTALPDLPSSIIRLDARFNRIQSSGLRPEAFRELKKLQFLHLSDN ELDYIPAPLPESLRSLHLQNNNIQTMHQDTFCDSQDLTHIRRALEDIRLDGNPINLSLFPSAYFCLPRLP TGRFY >XP_020753367.1 opticin [Odocoileus virginianus texanus] MKLLALLSLLILMLQEAGTASLSKEEREEDQPYGEGDSYAILHLGDYVLSLDNYDEIIDPSNYDELTDYG DQLPQVKGTGLASLTRTRFTQSTEVARTLPSNPMMARPPTLGLLAAPTKHGLPTCLICVCLGSSVYCDDT DLENIPPLPQTTAYLYARFNRISHIRAGDFKGLTKLKRIDLSGNSISSIDDKALRLLPALRDLILPENKL TALPALPTSIEVLDVRMNRLQSSGIQPEAFRALEKLQFLYLADNLLDAIPRSLPLSLRSLHLQNNMIETM RSDVFCDAEEHRHTRRQLEDVRLDGNPINLSLFPSAYFCLPRLPTGRFV >XP_031550322.1 uncharacterized protein LOC116287775 isoform X1 [Actinia tenebrosa] MWRLNRRKPVMHSKAFCRWAYFGTVYLVLIVYPNPVVSDNCPKGCKNCNESDGYFHTIRLVRTDCLHNSWMIDVPPGLPR TMGTLIFKSNAVKTIKTSSFQSYKYLKNLDLANNRIESIENRSFQYQEHLEKLDLMNNRLTNLTADMFVGLRSLEKLDLQ NNRISSLSRGVFRSMTELKYLDLHDNQISSIEDGAFGFLDYLQDIELGGCQLKSLQAGSFRNLMSLRTIDLSFNNIESID PDTFSCSPLLETLHLNGNGLKDVPVIVLSKLRLLKDLDLSENDLTSISSKAFFHNQDLEILNLGLCELSFLQEGAFDGLT NLRQVFLNENPLDCDCRLRWLLRFWNKSKDIFQEAELTNCTSPTHLSGKPLMDLSLAELKCDCKTCIQDAKCNGSACASC IQGGVAQSCNCSHLSLDGRSLCHSHNGSCICSHSVPKPTTRNCTFTMTNKTCDRNARLAVVGRRNISCQCNVGFQGDGVR CSDIDECAAGTNQCLERKCANTYGSYSCYCDHGYRVTKMKCEDINECDNDPCLGPSTCYNTPGSYYCECKSGHAIGDECW PVPNSIHIRVTEVQSTSVLVTWSNVTDNRDTIRSITILYRAYGTLLSEWPSAPEIYTPNTTQAVVKNLTPDTYYTIKVEL KLIYNISIFSDVQTFQTKELPTKGKPSGSDGNKSVVIVTSSVVGSAVAIAIALSLIALFLRRKKPKTGDEETDANRPYLQ DLMEMRMFSREANHENTQAVSNCMDAWEIPRDRLRVGEKIGEGQFGIVLKGTLTTSEGPVKVAIKTIKGVDRFEMKDFMQ EMDMMKEIGHHPNVVSLLGVSSIGAPLYIITEYVDGGDLLDLLRSSRRTDERYANMTSILNSRQLLGIALGVSKGMSHIA LKKLVHRDLAARNVLMTTELVAKIADFGLARDIYCEGMYVKTGGGRLPIKWMSPDAIRDQTYTIKSDVWSFGILLWEIVT LGGSPYPGIPVNILLEKLLYGYRMPKPEHCSDEVYSIMEECWALDPSMRPSFDDLCEALSLLLSEEGHTYINIKAISAEL IVKNSEPKEENSASV >XP_039262601.1 slit homolog 2 protein-like isoform X2 [Styela clava] MKDLVLPLTLLAVVGLGIACPSKCSCTEDTMQCIERGLTSVPTGIPRSIEKIELQGNNISHITRSDFAGLRKLRILYLDE NQIVSIEKNSFGENNLLEILRLNNNELTILPENLFSKLRALQRLDLSHNRIGIIQKKTFRGPNSLRTLQLSNNEISCLHE SSLRPVRSVEFLTLDNNKLTTLPLQSFEHLMKLRTFRFNNNPLNCDCHLAWISEWLISRPSAGLFTQCAEPSHLQGMEIK HLERGEFVCDASTGRQKPKCEMSSYCPSMCKCSNGIVDCRDKGLKSLPVSMPADVTEIRLEQNMIEVIPARAFARYRKLK RIDLSNNLISEVSEDSFQGLKHLNSLIMYENKITSLPKGIFAGLGNLQLLLLNANKLSCLRHDTFDGLVSLKLLSLYDNK LQIISKGTFRSLKSIQTLHLAQNPFICDCNLRWLADYLQDNPVETSGARCAAPRRLGNKKIAHVKSRRFKCEEGDNFPPP FAGECSPEAECPDKCRCDGSVIDCSRQQLTGVPDNIPPYATELNLAFNDIEILASLDIFKKLTNLKKIDLSNNKLMIIEE GAFNGAYSVLELWINDNELSDMNGGMFAGLRNLRTLMARNNRLKCISNATFAGLSSMTHLSLYGNQITSIVEGAFDSLTS LNLLNLLSNPLICNCHMSWLSVWLRTGTFSSGNPRCAEPSFLHGFPVADINPQDFHCSTEEKSQPPSCKPEIKCPERCLC EGTVVRCINVGLTAVPVDDIPETVTELYLNLNKIRLIPTSIKRFTKLEKLDLSNNLIATLQDNIFANFTRLSTLLLAYNK LRCLPPRGFSGLKNLRILSLHSNEISTVQHGTFDDLIALSHAGFGSNPWYCDCNLAWFNEWINKDYLEPGIAQCSGPSAV AGRVLLTTPIASFVCNDLPLSKCKRRKSRRRGPLSIPIASKCDPCLSTPCLHDGTCRLHPVEYYQCICPSGFKGKHCEMP VNACNLHPCRNGATCTGRDEISYTCTCPPGFSGYDCEINIDDCKMRPCRPDNATCIDGINTYTCKCPPGWSGDFCHIEIE DPCSENPCMNEGQCFPSLASDGQVEFRCECKIGFRGLNCSEEWDPCLDHKCENEAQCVMDGSNGAGYRCECSRGYRGQYC EFIDGHTALIQQDDPCIGNDCENGAQCYVEPGRASDFTCRCLPGYTGNKCQMLTGVSFLRNGSYAELHKAVEDQEYLQIT VEIATKELNGVILYAGESSQHITIELFAGHVRFSYDGINSAIYSEEIINDEEFHVIRLDIRTASVTMVIDDSRNYEAVSK KIVSTALPLYVGGIPANVLSNARRSWHIRNTTSFVGCLRNLNIDGEPVDFFTASQAGFSDLFQQDTGVRPGCSRDGLVST CSDLTCKFGECVANENGGSQCSCMEGYSGIYCDIEDSEPTACSGNRCQHGMCVVNGENASSYVCECDAGYGGEFCEIRDF CAGVDCGDHGTCVPHSSGHTCKCRMGYSGRNCASRIRRCSGTKTRQFVQITVARSSSDESPTTSSDMTSSSSDTMLCKSN KRITNLVCDSSSCTRISRRTARRRARGSESGHFRATTLRGLGAILNEEPPAPTCCAPLRQKRKNIELLCEDGTRITQQVT KVQSCGCQTCGQE
Mafft alignment of selected proteins >sp|Q9UBM4|OPT_HUMAN Opticin OS=Homo sapiens OX=9606 GN=OPTC PE=1 SV=1 ------------------------------------------------------------ -------------------------------MRLL-----AFLSLLALVLQETGTASLPR KERK--------------RREEQMPREG----------------------DSFEVLPLRN DVLNPDNYGEV-IDLSNYEELTDYGDQLPEVKV----------------TSLA-PATSIS PA------KSTT-----------------------------------APGTPS------- ----------------------SNPTMTRPT--------TAGLLLSSQPNH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GLPTC--------- ---LVCVCLGSSVYCDDIDLEDIPP-LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDL SNNLISSIDNDAFRLLHALQDLILPENQLEALPVLP----SGIEFLDVRLNRLQSSGIQP AAFRAMEKLQFLYLSDNLLDSIPG------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------LSLRSVHLQNNLIETMQRDVF----------- ------------------------------------------------------------ --------------CDPEEHKH-----------------------------------TRR QLEDIRLDGNPINL---------------------------------------------- SLFPSAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPI--------------------------------------------------- ------GRFT------------------------- >tr|Q15JE7|Q15JE7_DANRE Opticin OS=Danio rerio OX=7955 GN=optc PE=1 SV=1 ------------------------------------------------------------ -------------------------------MVIQRQTSKMLLYLVWILLGFSLGAPPT- --------------------------------------------------------DLDL EAFGLENYD----DPDSWDLHYNYDDEHEEV------------------ETVA-PPTALT PPPAVVVPENYV-----------------------------------EEMTLP------- ----------------------PRPTKSPVPSTLDFK--APG-LFGPDTGL--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GMPTC--------- ---LLCVCISGSVYCDDSDLTHIPP-LPKETTHFYARFNKITEIKAADFINLNQLKRIDL SGNQIGKVNEDAFRSLLQLQDLMMADNNIQALPELP----ASLKHIDIRNNKLRSSGMHA EAFKEMKELQFLYLSHNKLDYIPV------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------ESLRVLHLQNNNIQSITQDTF----------- ------------------------------------------------------------ --------------CNSHDKNY-----------------------------------IRK ALEDIRLDGNPVDI---------------------------------------------- NLYPQAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPV--------------------------------------------------- ------GTPV------------------------- >NP_473417.2 opticin isoform 1 [Mus musculus] MRGC----------LAVPCSDRQSSSPPEAPWK----------LLSQTEP---KASKRMY LRGIQPFPLLPL-----------PQNL----MKFL-----AFLSLLSLVLQKAETASLLG ERER----------------EEQSPEEG----------------------DTYASLYVGN HTLSIEDYNEV-IDLSNYEELADYGDQIPEAKI----------------SNLT-LPTRTS PT-------STV-----------------------------------AQKTLS------- ----------------------PNLTMAVPT--------TTG-LLNSQSSH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GLPTC--------- ---LVCVCLGSSVYCDDADLENIPP-LPQMTTYLYARFNHISHIQAGDFKGLTKLRRIDL SGNSISSIHNDALRLLPALQDLILPENQLAALPVLP----SGIEFLDVRLNRLQSSGIQP EAFVALKKLQFLYLANNMLDSIPG------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------LSLRSLHLQNNMIETMESDTF----------- ------------------------------------------------------------ --------------CDTGEHRH-----------------------------------ERR QLEDIRLDGNPINL---------------------------------------------- SLFPEAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPV--------------------------------------------------- ------GHFT------------------------- >XP_038946639.1 opticin isoform X1 [Rattus norvegicus] MGNLIRHMDPWANYLSSPWPINEGVSSCPLVWQAVIIPIRVFVSLEAAGPDGTKTSKRMY VEWIQPFPLLPF-----------PQNL----MKFL-----TFLSLLTLVLQEAGTASLLG ERER----------------EEKSPEEA----------------------DTYASLHVGN YSLSLEDYSEV-IDLSSYEELADYGDQIPEAKT----------------SSPT-LPTRTS PT-------SPV-----------------------------------VPRTLP------- ----------------------SRLTMAGPT--------TTG-LLNSQSSH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GLPTC--------- ---LVCVCLGSSVYCDDANLENIPP-LPQMTTYLYARFNHISHIQAGDFKGMTKLRRIDL SSNSISSIHNDALRLLPALQDLILPENQLAALPVLP----SGLEFLDVRLNRLQSSGIQP EAFVTLEKLQFLYLADNLLDSIPG------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------LSLRSLHLQSSSVHS--RDLF----------- ------------------------------------------------------------ --------------HALHTHLP-----------------------------------TQN SRRTMKGRGG--RG---------------------------------------------- GGRGTEAG---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------ME------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----GRVGR--------------------------------------------------- ------GRVISVL---------------EPGLSDW >NP_989804.1 opticin precursor [Gallus gallus] M----------------------------------------------------ALGHR-- -------------------------------MQTL-----AWVGIASLCLGAAWAVPAKK ERKK----------------VEKLKPDL----------------------VLYENLDLDN YDVTLDNYGDI-MDLNNYEELYDYGDLAPKIEV----------------GTLA-PRPKDR ESLPE---LVTA-----------------------------------APTPKL------- ----------------------QPPDTTNPI--------RPA-PPGPGTAQ--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GVPSC--------- ---LPCLCIRTSVYCDDTDLEHIPP-LPPDTTYLYARFNRISAIRAGDFMGLKKLKRIDL TSNSISWADVDAFRFLPSLQELILPENRLTALPELP----RSIIRLDARLNRIPSAGLRP EAFQDLTQLQFLHLSDNQLDYIPA------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------ESLRSLHLQNNNIQTMHEDTF----------- ------------------------------------------------------------ --------------CNSQDQSH-----------------------------------VRR ALEDIRLDGNPINL---------------------------------------------- SLFPNAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPT--------------------------------------------------- ------GHFL------------------------- >NP_999173.1 opticin precursor [Sus scrofa] ------------------------------------------------------------ -------------------------------MKLL-----ALLSLLALMLQEAGTASLPE KERE--------------RGEDRLHRES----------------------DSSTALHLGD YTLSPDSHDGV-LDLSNYEELMDYGDQLPKVKG----------------ASLA-SPTRAS ST------QSMK-----------------------------------PPRTPP------- ----------------------SSPTVARPT--------ALS-PPGSPTSHA-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------PGLPTC--------- ---LVCVCLGSSVYCDDTDLENIPP-LPQTTTYLYARFNRINHIRAGDFKGLTKLKRIDL SSNFISSIDDDALLLLPDLQDLILIENQLAALPTLP----TAIEVLDVRLNRLRSSGIQP GAFRALEKLQFLYLADNLLDSIPG------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------LSLRSLHLQNNMIETLQRDTF----------- ------------------------------------------------------------ --------------CDPEEHKH-----------------------------------TRR QLEDIRLDGNPINL---------------------------------------------- SLFPSAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPI--------------------------------------------------- ------GRFT------------------------- >NP_001003056.1 opticin precursor [Canis lupus familiaris] ------------------------------------------------------------ -------------------------------MKLP-----AFLSLLALVLLEAGTASLPK ERKR----------------RDEMHGEG----------------------DSYVV--LGN YVLGPDNYDEV-IDLSDYEGLMDYGDQLPEAKV----------------TNLA-PPTGIS SA------QSTM-----------------------------------TPRTLS------- ----------------------LKPTMIRPT--------ELG-VLGSPNSH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GLPTC--------- ---LICVCLGSSVYCDDADLENIPP-LPKTTTYLYARFNRIRRIRAGDFKGLTKLKRIDL SSNSISSIDDDALRLLPALQDLILPENQLAALPALP----PAIEVLDARHNQLQSSGIQP EALRALEKLQFLYLADNLLDSIPG------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------PSLRSLHLQNNLIETMQTDAF----------- ------------------------------------------------------------ --------------CDPEEHKH-----------------------------------SRR WLEDIRLDGNPINL---------------------------------------------- GLFPSAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPT--------------------------------------------------- ------GHCC------------------------- >NP_991339.1 opticin precursor [Bos taurus] ------------------------------------------------------------ -------------------------------MKLL-----ALLSLLILMLQEARTASLSE ER------------------------EG----------------------DPYAILHLGD YVLSLDNYDEV-IDPSNYDELIDYGDQLPQVKG----------------TSLA-SLTRTR FT------QSTE-----------------------------------AARTLP------- ----------------------SNPTTARPP--------TLG-LLAAPANH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GLPTC--------- ---LICVCLGSSVYCDDADLENIPP-LPQTTAYLYARFNRISHIRAGDFKGLTKLKRIDL SGNSISSIDDKALRLLPALRDLILPENKLVALPTLP----TSIEVLDVRMNRLQSSGIQP EAFRALEKLQFLYLADNLLDAIPP------------------------------------ -----------------------------------SLP---------------------- ------------------------------------------------------------ ----------------------------LSLRSLHLQNNMIETMQRDAF----------- ------------------------------------------------------------ --------------CDAEEHRH-----------------------------------TRR PLEDIRLDGNPINL---------------------------------------------- SLFPSAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPT--------------------------------------------------- ------GRFV------------------------- >XP_016791796.1 opticin [Pan troglodytes] ------------------------------------------------------------ -------------------------------MRLL-----AFLSLLALVLQETGTASLPR KERK--------------RREEQMPREG----------------------DSFEVLPLRN DVLNPDNYGEV-IDLSNYEELTDYGDQLPEVKM----------------TSLA-PATSIS PT------KSTT-----------------------------------APGTPS------- ----------------------SNPTMTRPT--------TAGLLLSSQPNH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GLPTC--------- ---LVCVCLGSSVYCDDIDLEDIPP-LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDL SNNLISSIDNDAFRLLHALQDLLLPENQLEALPVLP----SGIEFLDVRLNRLQSSGIQP AAFRAMEKLQFLYLSDNLLDSIPG------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------LSLRSVHLQNNLIETMQRDVF----------- ------------------------------------------------------------ --------------CDPEEHKH-----------------------------------TRR QLEDIRLDGNPINL---------------------------------------------- SLFPSAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPI--------------------------------------------------- ------GRFT------------------------- >XP_017203333.1 PREDICTED: opticin [Oryctolagus cuniculus] ------------------------------------------------------------ -------------------------------MRLP-----AFLSLLALVLQ--------- --------------------------EG----------------------DPHTALPLDD YGLSPDDYGEV-LDLGNYEEPTDYGEQPLEVKA----------------TSPAPPPTRGS PI------QSAK-----------------------------------ALRTPS------- ----------------------SSPTVPGP-----------------PTNH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------SLPTC--------- ---LVCVCLGSSVYCDDADLESIPP-LPKTTTYLYARFNRIRRVRAGDFQGLAKLKRIDL SSNVISYIESDALRALPALQDLLLPENQLAALPALP----SSVQLLDARLNRLQSSGIQP GAFRALEKLQFLYLADNLLDSVPG------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------LSLRSLHLQNNAIGTLRGDEF----------- ------------------------------------------------------------ --------------CDAEEHRH-----------------------------------TRR PLEDVRLDGNPVNL---------------------------------------------- SLFPDAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPT--------------------------------------------------- ------GRMV------------------------- >XP_002809624.1 opticin [Pongo abelii] ------------------------------------------------------------ -------------------------------MRLL-----AFLSLLALVLQETGTASLPR KERK--------------RREEQMPREG----------------------DSFEVLPLRN DVLNPDNYGEV-IDLSNYEELTDYGDQLPEVKV----------------TSLA-PATSIN PA------KSTT-----------------------------------APGTPS------- ----------------------SNPTMTRPT--------TAGLLLSSQPNH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GLPTC--------- ---LVCVCLGSSVYCDDIDLEDIPP-LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDL SNNLISSIDNDAFRLLHALQDLILPENKLEALPVLP----SGIEILDVRLNRLQSSGIQP AAFRAMEKLQFLYLSDNLLDSIPG------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------LSLRSVHLQNNLIETMQRDVF----------- ------------------------------------------------------------ --------------CDPEEHKH-----------------------------------TRR QLEDIRLDGNPINL---------------------------------------------- SLFPSAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPI--------------------------------------------------- ------GRFT------------------------- >XP_003203890.1 opticin [Meleagris gallopavo] M----------------------------------------------------ALGHR-- -------------------------------MKTL-----AWVGIASLCLGATWAVPAKK ERKK----------------VEKPKPDL----------------------VLNENLDLDN YDMTLDSYGDI-MDLNNYEELYDYGDLAPKVEV----------------GTLA-PRPKDH GALPE---LGTA-----------------------------------APTPKL------- ----------------------KPLATTNPT--------HPA-PLGLNTAQ--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GLPSC--------- ---LRCLCIRTSVYCDDTDLEHIPP-LPPDTTYLYARFNRIGAIRAGDFMGLKKLKRIDL TSNSISWADVDAFRLLPSLQELILPENRLTALPELP----RSIVRLDARLNRIPSAGLRP EAFQDLTQLQFLHLSDNQLDYIPA------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------ESLRSLHLQNNNIQTMHEDTF----------- ------------------------------------------------------------ --------------CNSQDQSH-----------------------------------IRR ALEDIRLDGNPINL---------------------------------------------- SLFPNAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPT--------------------------------------------------- ------GRFF------------------------- >XP_003823034.1 opticin isoform X1 [Pan paniscus] ------------------------------------------------------------ -------------------------------MRLL-----AFLSLLALVLQETGTASLPR KERK--------------RREEQMPREG----------------------DSFEVLPLRN DVLNPDNYGEV-IDLSNYEELTDYGDQLPEVKM----------------TSLA-PATSIS PA------KSTT-----------------------------------APGTPS------- ----------------------SNPTMTRPT--------TAGLLLSSQPNH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GLPTC--------- ---LVCVCLGSSVYCDDIDLEDIPP-LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDL SNNLISSIDNDAFRLLHALQDLILPENQLEALPVLP----SGIEFLDVRLNRLQSSGIQP AAFRAMEKLQFLYLSDNLLDSIPG------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------LSLRSVHLQNNLIETMQRDVF----------- ------------------------------------------------------------ --------------CDPEEHKH-----------------------------------TRR QLEDIRLDGNPINL---------------------------------------------- SLFPSAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPI--------------------------------------------------- ------GRFT------------------------- >XP_006942942.2 opticin isoform X1 [Felis catus] MGD--------------PLSKEKGEQLDTSKRRSLI----GHTLASASTPLSTLAHCR-- ----RPFQQSPYFSGGCEALFLRKQHCVGVPMKIL-----AFQILLALVLLEAGTASPPK GRKR----------------RDPTNEEG----------------------DSYAVLNLGN YVPDLDNYDEV-IDLSDYEGLMDYGDQLPEVKAG---------------SSLG-PPTRIG ST------QSTV-----------------------------------NPRTLS------- ----------------------SKPTMTKPT--------MLG-LPGSPSSHA-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------EPGLPTC--------- ---LVCVCLGSSVYCDDADLESIPP-LPKTTTYLYARFNRISRIRAGDFKGLTKLKKIDL SSNSISSIDDDALRLLPALRDLILPENQLAALPVLP----AGIEVLDVRLNRLQSSGIQP EAFRGLERLQFLYLADNLLDSIPG------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------PSLRSLHLQNNMIETMQKDAF----------- ------------------------------------------------------------ --------------CDTEEHKH-----------------------------------SRR RLEDIRLDGNPINL---------------------------------------------- GFFPSAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPT--------------------------------------------------- ------GRCC------------------------- >XP_027831905.1 opticin [Ovis aries] ------------------------------------------------------------ -------------------------------MKLL-----ALLSLLILMLQEAGTAPLSK EERG----------------EEQPYGEG----------------------DSYAILHLGD YVLSLDNYEEV-IDPSNYDELTDYGDQLPQVKG----------------TSLA-SLTRTR FT------QSTE-----------------------------------AARTLP------- ----------------------SNPTTARPP--------TLG-LLAAPANH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GLPTC--------- ---LICVCLGSSVYCDDADLENIPP-LPQTTAYLYARFNRISHIRAGDFKGLTKLKRIDL SGNSISSIDDKALRLLPALRDLILSENKLVALPALP----TSIEVLDVRMNRLQSSGIQP EAFRALEKLQFLYLADNLLDAIPW------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------LSLRSLHLQNNMIETMQRDAF----------- ------------------------------------------------------------ --------------CDAEEHRY-----------------------------------TRR QLEDIRLDGNPINL---------------------------------------------- SRFPSAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPT--------------------------------------------------- ------GRFV------------------------- >XP_018884560.1 opticin [Gorilla gorilla gorilla] ------------------------------------------------------------ -------------------------------MRLL-----AFLSLLALVLQETGTASLPR KERK--------------RREEQMPREG----------------------DSFEVLPLRN DVLNPDNYGEV-IDLSNYEELTDYGDQLPEVKV----------------TSLA-PATSIS PA------KSTT-----------------------------------APGTPS------- ----------------------SNPTMTRPT--------TAGLLLSSQPNH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GLPTC--------- ---LVCVCLGSSVYCDDIDLEDIPP-LPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDL SNNLISSIDNDAFRLLHALQDLILPENQLEALPVLP----SGIEFLDVRLNRLQSSGIQP AAFRAMEKLQFLYLSDNLLDSIPG------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------LSLRAVHLQNNLIETMQRDVF----------- ------------------------------------------------------------ --------------CDPEEHKH-----------------------------------TRR QLEDIRLDGNPINL---------------------------------------------- SLFPSAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPI--------------------------------------------------- ------GRFT------------------------- >XP_021154000.1 opticin [Columba livia] ------------------------------------------------------------ -------------------------------MWAL-----AWLGIASLCLGTAWAVPA-K ERRK----------------AEKPKAHL----------------------ALYENLDLDN YDLTLDNYGEI-LDLSNYEELYDYGDLAPKIEV----------------GTLA-PRPKDP AAPPD---LGTT-----------------------------------AETPKL------- ----------------------QLLSTAGPV--------PPA----PIPVQ--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------ALPSC--------- ---QLCLCIGTSVYCDDADLEHIPP-LPPETTYLYARFNRIGTIQASDFMGLKKLKLIDL SSNSITRADADAFRLLPSLQELILPENRLTALPELP----RSIVRLDARLNSIPSTGLRP DAFRDLKQLQFLHLSDNQLDYIPA------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------ESLRSLHLQNNNIQTMHEDTF----------- ------------------------------------------------------------ --------------CDSQDHSQ-----------------------------------VRR ALEDIRLDGNPINL---------------------------------------------- SLFPNAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPT--------------------------------------------------- ------GRFS------------------------- >KAB0342281.1 hypothetical protein FD754_019207 [Muntiacus muntjak] ------------------------------------------------------------ -------------------------------MKLL-----ALLSLLILMLQEAGTASLSK EERE----------------EDQPYGEG----------------------DSYAILHLGD YVLSLDNYDEV-IDPSNYDELTDYRDQLPQVKG----------------TGLA-SLTRTR FT------QSTE-----------------------------------VARTLP------- ----------------------SNPTMARPP--------TLG-LLAAPANH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GLPTC--------- ---LICVCLGSSVYCDDTDLENIPP-LPQTTAYLYARFNRISHIRAGDFKGLTKLKRIDL SGNSISSIDDKALRLLPALRDLILPENKLAALPVLP----TSIEVLDVRMNRLQSSGIQP EAFRALEKLQFLYLADNLLDAIPR------------------------------------ -----------------------------------SLP---------------------- ------------------------------------------------------------ ----------------------------LSLRSLHLQNNMIETMQSDVF----------- ------------------------------------------------------------ --------------CDAKEHRH-----------------------------------TRR QLEDIRLDGNPINL---------------------------------------------- SLFPSAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPT--------------------------------------------------- ------GRFV------------------------- >KAB0376678.1 hypothetical protein FD755_011122 [Muntiacus reevesi] ------------------------------------------------------------ -------------------------------MKLL-----ALLSLLILMLQEAGTASLSK EKRE----------------GDQPYGEG----------------------DSYAVLHLGD YVLSLDNYDEV-IDPSNYDELTDYRDQLPQVKG----------------TGLA-SLTRTR FT------QSTE-----------------------------------VARTLP------- ----------------------SNPTMARPP--------TLG-LLAAPANH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GLPTC--------- ---LICVCLGSSVYCDDTDLENIPP-LPQTTAYLYARFNRISHIRAGDFKGLTKLKRIDL SGNSISSIDDKALRLLPALRDLILPENKLAALPVLP----TSIEVLDVRMNRLQSSGIQP EAFRALEKLQFLYLADNLLDAIPR------------------------------------ -----------------------------------SLP---------------------- ------------------------------------------------------------ ----------------------------LSLRSLHLQNNMIETMQSDVF----------- ------------------------------------------------------------ --------------CDAEEHRH-----------------------------------TRR QLEDVRLDGNPINL---------------------------------------------- SLFPSAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPT--------------------------------------------------- ------GRFV------------------------- >KAF4018212.1 hypothetical protein G4228_010223 [Cervus hanglu yarkandensis] ------------------------------------------------------------ -------------------------------MKLL-----ALLSLLILMLQEAGTASLSK EERE----------------EDQPYGEG----------------------DSYAVLHLGD YVLSLDNYDEV-IDPSNYDELTDYGDQLPQVKG----------------TGLA-SLTRTR FT------QSTE-----------------------------------VARTLP------- ----------------------SNPTMGRPP--------TLG-LLAAPTDL--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GLPTC--------- ---LICVCLGSSVYCDDTDLENIPP-LPQTTAYLYARFNRISHIRAGDFKGLTKLKRIDL SGNSISSIDDKALRLLPALRDLILPENKLAALPALP----TSIEVLDVRMNRLQSSGIQP EAFRALEKLQFLYLADNLLDAIPR------------------------------------ -----------------------------------SLP---------------------- ------------------------------------------------------------ ----------------------------LSLRSLHLQNNMIETMQSDVF----------- ------------------------------------------------------------ --------------CDAEEHRH-----------------------------------TRR QLEDVRLDGNPINL---------------------------------------------- SLFPSAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPT--------------------------------------------------- ------GRFV------------------------- >XP_043341198.1 opticin [Cervus canadensis] ------------------------------------------------------------ -------------------------------MKLL-----ALLSLLILMLQEAGTASLSK EERE----------------EDQPYGEG----------------------DSYAVLHLGD YVLSLDNYDEV-IDPSNYDKLTDYGDQLPQVKG----------------TGLA-SLTRTR FT------QSTE-----------------------------------VARTLP------- ----------------------SNPTMGRPP--------TLG-LLAAPTDL--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GLPTC--------- ---LICVCLGSSVYCDDTDLENIPP-LPQTTAYLYARFNRISHIRAGDFKGLTKLKRIDL SGNSISSIDDKALRLLPALRDLILPENKLAALPALP----TSIEVLDVRMNRLQSSGIQP EAFRALEKLQFLYLADNLLDAIPR------------------------------------ -----------------------------------SLP---------------------- ------------------------------------------------------------ ----------------------------LSLRSLHLQNNMIETMQSDVF----------- ------------------------------------------------------------ --------------CDAEEHRH-----------------------------------TRR QLEDVRLDGNPINL---------------------------------------------- SLFPSAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPT--------------------------------------------------- ------GRFV------------------------- >OWK08495.1 OPTC [Cervus elaphus hippelaphus] ------------------------------------------------------------ -------------------------------MKLL-----ALLSLLILMLQEAGTASLSK EERE----------------EDQPYGEG----------------------DSYAVLHLGD YVLSLDNYDEV-IDPSNYDKLTDYGDQLPQVKG----------------TGLA-SLTRTR FT------QSTE-----------------------------------VARTLP------- ----------------------SNPTMGRPP--------TLG-LLAAPTDL--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GLPTC--------- ---LICVCLGSSVYCDDTELENIPP-LPQTTAYLYARFNRISHIRAGDFKGLTKLKRIDL SGNSISSIDDKALRLLPALRDLILPENKLTALPMLP----TSIEVLDVRMNRLQSSGIQP EAFRALEKLQFLYLADNLLDAIPR------------------------------------ -----------------------------------SLP---------------------- ------------------------------------------------------------ ----------------------------LSLRSLHLQVSGCSGNKG-------------- ------------------------------------------------------------ ----------------VERHRR-----------------------------------WRS DCRE------P------------------------------------------------- ---PSAVV---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------GL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----RH------------------------------------------------------ ----------------------------------- >XP_018104794.1 opticin [Xenopus laevis] ------------------------------------------------------------ -------------------------------MYLF-----IALCVSGIALCSAPPSPGAS RNNK---------------------EKH----------------------RSGENIKLVD YNI---NYEES-IDIRKYEELHDYYDHEPK-EV----------------HTLT-PLNKKS GLLTN---QGTE-----------------------------------NPITL-------- ------------------------PSIPKPS--------EHS-LFGSMTEQ--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GLPIC--------- ---LVCACIGTSVYCDDVDLNGIPP-LPKDTAYLYARFNRITRINNNDFKGLNKLKRVDL SSNFLSKIDDDAIHFLPSLQELILSENQLKALPELP----SSLTRLDVQYNQLQSSGIQT DAFKDLTSLEYLYLSNNKLDYIPV------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------YSLRSLHLQNNNIQTMNLETF----------- ------------------------------------------------------------ --------------CESRDLTF-----------------------------------IRR NLEDIRMDDNPINL---------------------------------------------- SKFVHGYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----VRLPT--------------------------------------------------- ------GSYY------------------------- >XP_030296407.1 epiphycan isoform X3 [Sparus aurata] ------------------------------------------------------------ -------------------------------MRML-----VRLVLGLLVLKAVVAGPRFS RQVD------------------------------------------------LDSYDSAN YDVDLDNLNSENQDIYDYDDGLTIDD--PQIEI----------------GTLA-PPDYNY PVPEASLEEQEQEEEE-------------------------------EEEEMPL------ ---------------------KPQLIPQGSG--------GSGVLMGPDTQK--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GMPTC--------- ---LLCTCLGGSVYCDDLKLDSVPP-LPKDTTHFYARYNRITKINKSDFAFLNKLKRIDL TANEITSVDDRAFMALPELEELVIRENHISQLPALP----ETMTLIDASHNNIGTKGIHN EAFKDMTSLLYLYLTDNHVDYIPV------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------DSLRSLHLQRNNIQMMHEDTF----------- ------------------------------------------------------------ --------------CNLKDFNY-----------------------------------IRN ALEDIRLDGNPINL---------------------------------------------- SRTPQAYI---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRIPI--------------------------------------------------- ------GDLI------------------------- >XP_015815457.1 PREDICTED: dentin sialophosphoprotein-like [Nothobranchius furzeri] ------------------------------------------------------------ -------------------------------MRML-----VRLVLGLFVLKAAIASPRFS RQVD------------------------------------------------LDTYDLAN YDEEEDNFDLDNGESYDYDEELTTDE--SETET----------------ETPN-ELDYNH P-PEDLEEEKPEEEEDVQQEKGGEEENQEEKEEEDNHEEEYNQGEENEEEELPL------ ---------------------TPQLIPQGSG--------GSGVLMGPDTQKEVELRRVPV DTLHVSGDFGGSAGSGASGASGASGASGASGSGGSGDILVSGASGESGEIIMMSGASEEL FSSGGPEELL---SGDILISGDLSGSGVTSGSGVSGFSGDIPSGESEFVTELPVGSGGSG DPSGSGFSGDILISGASGISGASGISGASGISGVSGDSFESGQSGITFITEEEERPLVPE IIPQEASGGSGEISGVSGTSGASGDIGVSGGLEVSGTSGTSGVSASGDIEVPEVNLLPEP EEEEELLPTTPEPSQEVQTSIEETMTSG-----DPEQPEEEVVDAQGMPVC--------- ---LLCTCLGGSVYCDDLKLDSVPP-LPKDTTHFYARYNKITKINKSDFANMNKLKRIDL TANEITAIDDKAFMGLPALEQLIIRENHVSQLPALP----ETMTLIDGSHNNIGSRGIHK EAFKDMTSLQFLYLTDNNIDYIPV------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------DSLRSIHLQRNNIQMMHEDTF----------- ------------------------------------------------------------ --------------CNLNDFNY-----------------------------------IRN ALEDIRLDGNPINL---------------------------------------------- SKTPQAYI---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRIPV--------------------------------------------------- ------GNLV------------------------- >XP_004083110.1 aggrecan core protein [Oryzias latipes] ------------------------------------------------------------ -------------------------------MRMF-----VRLVLGLFVLKAAVASPRFS RQAN------------------------------------------------LDIYDDAN YDEELNNVESE--DTYDYEDGLTIDE--PEIEI----------------ETMA-LPDYTF P-------EEEKPEEG-------------------------------EEEELTL------ ---------------------RPQPIPQGSG--------GSGVLMGPETQKEVELRQEPV DILHASGDLGGS-GSG----SGTSGASGASGSGESGDLLI------SGDIILISGASETL ISSEGSGEFLISEKTDFTIPWHTSGSGFESSP--SGASGDLTSGHSGISIEIPFGSGESG E---SGESGDL-----SGISPDPSISGASGSSGVSGDPAESGDLGITLISGDEKPFVISK HEPQEASVASGEISGVS-----------SADTEISGTSGVSGVSTSGDDEEP-VTVIIET KEEERVLSTTPETPQEGATSIEETDSSGLPEPFEPKEPDEPKIDISGMPTC--------- ---LLCTCLGTSVYCDDLKLDSVPP-LPKETTHFYARYNKITKINKSDFAFMNKLKRVDL TANEITAIDGTAFIGLPELEELVVRQNHLTQLPALP----ETMTLIDASHNSIGSKGIHK EAFKDMTGLLFLYLTDNNIDYIPV------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------ESLRSLHLQRNNIQMMHEDTF----------- ------------------------------------------------------------ --------------CNLNDFNY-----------------------------------IRN ALEDIRLDGNPINL---------------------------------------------- SKTPQAYV---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRIPI--------------------------------------------------- ------GNLI------------------------- >XP_040200080.1 epiphycan [Rana temporaria] ------------------------------------------------------------ -------------------------------MKTL-----ANIFLGLLIIKAVVSAPPT- --------------------------------------------------------DSVN YDTAAYEVDLL-YNLYDYDENTNIDQ--GEIEI----------------GTVL--PVVNR PILSPEPVQEEIEEEEE------------------------------STPKLI------- ----------------------DGSSPQGPL--------SPGV---PEASG--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GVSTC--------- ---ILCGCIRTTVYCDDHNLDAVPP-LPKDTTHVYLRFNRISKINKNDFSYLSKLQKIDL TSNIISDIDEDAFRSLSQLDELILLDNNIRQLPELP----HSVSFLDVSKNRLGRKGIKQ EAFKDLNDLRLLYLNNNNLDHIPI------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------DSLQALHLQDNNIQEMHEDTF----------- ------------------------------------------------------------ --------------CNMKDFTY-----------------------------------ARR SLEDIRLDGNPINL---------------------------------------------- SKTPQAFM---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRIPV--------------------------------------------------- ------GRLV------------------------- >XP_005690430.1 PREDICTED: opticin [Capra hircus] ------------------------------------------------------------ -------------------------------MKLP-----ALLSLLILMLQEAGTASLSK EERG----------------EEQPYGEG----------------------DSYAILHLGD YVLSLDNYEEV-IDPSNYDELTDYGDQLPQVKG----------------TSLA-SLTRTR FT------QSTE-----------------------------------AARTLP------- ----------------------SNPTTARPP--------TLG-LLAAPANH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GLPTC--------- ---LICVCLGSSVYCDDADLENIPP-LPQTTAYLYARFNRISHIRAGDFKGLTKLKRIDL SGNSISAIDDKALRLLPALRDLILPENQLVALPALP----TSIEVLDVRMNRLQSSGIQP EAFRALEKLQFLYLADNLLDAIPR------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------LSLRSLHLQNNMIETMQRDAF----------- ------------------------------------------------------------ --------------CDAEEHRY-----------------------------------TRR QLEDIRLDGNPINL---------------------------------------------- SLFPSAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPT--------------------------------------------------- ------GRFV------------------------- >XP_006025086.1 opticin [Alligator sinensis] ------------------------------------------------------------ -------------------------------MPSA-----VLLGMITLALAALALAVPLG EGKK----------------TEKPSTDL----------------------TIYESLNLDN YDLSLNNYGDI-IDLSNYDELYDYGDLAPKIEV----------------GTLA-PPAKTP EGMPSTRAVPTA-----------------------------------TPRKEL------- ----------------------PMSTTAKPV--------GPG-LLGFITEQ--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GLSTC--------- ---LVCVCIGTSVYCDDAGLEHIPA-LPLETMYLYARFNSIGQIRARDFAGLKKLKRIDL TSNYISSVEEGSFRQLTSLQELILPENRLTVLPDLP----SSIIRLDARFNRIQSSGLRP EAFRELKKLQFLHLSDNELDYIPA------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------ESLRSLHLQNNNIQTMHQDTF----------- ------------------------------------------------------------ --------------CDSQDLTH-----------------------------------IRR ALEDIRLDGNPINL---------------------------------------------- SLFPSAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPT--------------------------------------------------- ------GRFY------------------------- >XP_019347037.1 PREDICTED: opticin [Alligator mississippiensis] MRVL-----------------------ESMGWECVH---------------ALAHMHR-- -------------------------------MPSV-----VLLGMITLMLAALALAVPLG EGKK----------------TEKPSADL----------------------TIYESLNLDS YDLSLNNYGDI-IDLSNYDELYDYGDLAPKIEV----------------GTLA-PPAKTP EGMPSTRAVPTA-----------------------------------APRKQP------- ----------------------PMPTTAKPV--------GPG-LLGFITEQ--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GLSTC--------- ---LVCVCIGTSVYCDDAGLEHIPA-LPLETMYLYARFNSIGQIRARDFAGLKKLKRIDL TSNYISSVEEGSFRQLTSLQELILPENRLTALPDLP----SSIIRLDARFNRIQSSGLRP EAFRELKKLQFLHLSDNELDYIPA------------------------------------ -----------------------------------PLP---------------------- ------------------------------------------------------------ ----------------------------ESLRSLHLQNNNIQTMHQDTF----------- ------------------------------------------------------------ --------------CDSQDLTH-----------------------------------IRR ALEDIRLDGNPINL---------------------------------------------- SLFPSAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPT--------------------------------------------------- ------GRFY------------------------- >XP_020753367.1 opticin [Odocoileus virginianus texanus] ------------------------------------------------------------ -------------------------------MKLL-----ALLSLLILMLQEAGTASLSK EERE----------------EDQPYGEG----------------------DSYAILHLGD YVLSLDNYDEI-IDPSNYDELTDYGDQLPQVKG----------------TGLA-SLTRTR FT------QSTE-----------------------------------VARTLP------- ----------------------SNPMMARPP--------TLG-LLAAPTKH--------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------------------GLPTC--------- ---LICVCLGSSVYCDDTDLENIPP-LPQTTAYLYARFNRISHIRAGDFKGLTKLKRIDL SGNSISSIDDKALRLLPALRDLILPENKLTALPALP----TSIEVLDVRMNRLQSSGIQP EAFRALEKLQFLYLADNLLDAIPR------------------------------------ -----------------------------------SLP---------------------- ------------------------------------------------------------ ----------------------------LSLRSLHLQNNMIETMRSDVF----------- ------------------------------------------------------------ --------------CDAEEHRH-----------------------------------TRR QLEDVRLDGNPINL---------------------------------------------- SLFPSAYF---------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------CL------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----PRLPT--------------------------------------------------- ------GRFV------------------------- >XP_031550322.1 uncharacterized protein LOC116287775 isoform X1 [Actinia tenebrosa] ------------------------------------------------------------ -------------------------------MWRL------------------------- NRRK-------------------------------------------------------- ----------------------------PVMHS----------------KAFC------- ------------------------------------RWAYF------GTVYLVLIVY--- ----------------------PNPVVSDNC----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------PKGCKNCNESDGYFHT IRLVRTDCLHNSWMID------VPPGLPRTMGTLIFKSNAVKTIKTSSFQSYKYLKNLDL ANNRIESIENRSFQYQEHLEKLDLMNNRLTNLTADMFVGLRSLEKLDLQNNRI--SSLSR GVFRSMTELKYLDLHDNQISSIEDGAFGFL-----------------------DYLQD-- IELGGC-----------------------------QLK---------------------- ------------------------------------------------------------ ------------------SLQAGSFRNLMSLRTIDLSFNNIESIDPDTF----------- ------------------------------------------------------------ -------------SCSP------------------------------------------- LLETLHLNGNGLKDVPVIV-----LSKLRL------------------LKDLDLSENDLT SISSKAFFHNQDLEILNLGLCELSFLQEGAFDGLTNLRQVFLNENPLDCDCRLRWLLRFW NKSKDIFQEAELTNCTSPTHLSGKPLMDLSLAELKCD------CK--------------- ---------TCIQDAKC----------------------------------NGSACASCI QGGVAQSCNCS--------HLSLDGRSL--CHSHNGSCI------------------CSH SVPKPTTRN-CTFTMTNKTCDRNARLAVVGRRNISCQCNVGFQGDGVRCSDIDECAAGTN QCLERKCANTY---------GSYSCYCDHGYRVTKMKCEDINE-----CDNDPCLGP--- --STCYNTPG---SYYCECKSGHAIGDECWPVPN----------SIHIRVTEVQSTSVLV TWSNVTDN------RDTIRSITILYRAYGTLLSEWPSAPEIYTPNTTQAVVKNLTPDTYY TIKVELKLIYNISIFSDVQTFQ--TKELPTKGKPSGSDGNKSVVIV----------TSSV VGSAVAIAIALSLIALFLRRK-------KPKTGDEETDANRPYLQDLMEMR-MFSREANH ENTQAVSNCMDAWEIPRDRLRVGEKIG----EGQFGI-VLKGTLTTSEGPVKVAIKTIKG VDRFEMKDFMQEMDMMKEIGHHPNVVSLLGVSSIGAPLYIITEYVDGGDLLDLLRSSRRT DERYANMTSILNSRQLLGIALGVSKGMSHIALKKLVHRDLAARNVLMTTELVAKIADFGL AR------DIYCEGMYVKTGGGRLPIKWMSPDAIRDQTYTIK-SDVWSFGILLWEIVTLG GSPYPGIPV--NILLEKLLYGYRMPKPEHCSDEVYSIMEECWALDPSMRPSFDDLCEALS LLLSEEGHTYINIKAISAELIVKNSEPKEENSASV >XP_039262601.1 slit homolog 2 protein-like isoform X2 [Styela clava] ------------------------------------------------------------ -------------------------------MKDLV-LPLTLLAVVGLGIACPSKCSCTE DTMQCIERGLTSVPTGIPRSIEKIELQGNNISHITRSDFAGLRKLRILYLDENQIVSIEK NSFGENNLLEI-LRLNNNELTILPENLFSKLRALQRLDLSHNRIGIIQKKTFR-GPNSLR TLQLSNNEISCLHESSLRP----------------VRSVEFLTLDNNKLTTLPLQSFEHL MKLRTFRFNNNPLNCDCHLAWISEWLISRPSAGLFTQCAEPSHLQGMEIKH--------- --------------------------------------------LERGEFVC-------- ---------------------------------------DASTG---------------- ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------RQKPKCEMS-----S YCPSMCKCSNGIVDCRDKGLKSLPVSMPADVTEIRLEQNMIEVIPARAFARYRKLKRIDL SNNLISEVSEDSFQGLKHLNSLIMYENKITSLPKGIFAGLGNLQLLLLNANKL--SCLRH DTFDGLVSLKLLSLYDNKLQIISKGTFRSLKSIQTLHLAQNPFICDCNLRWLADYLQDNP VETSGARCAAPRRLGNKKIAHVKSRRFKCEEGDNFPPPFAGECSPEAECPDKCRCDGSVI DCSRQQLTGVPDNIPPYATELNLAFNDIEILASLDIFKKLTNLKKIDLSNNKLMIIEEGA FNGAYSVLELWINDNELSDMNGGMFAGLRNLRTLMARNNRLKCISNATFAGLSSMTHLSL YGNQITSIVEGAFDSLTSLNLLNLLSNPLICNCHMSWLSVWLRTGTFSSGNPRCAEPSFL HGFPVADINPQDFHCSTEEKSQPPSCKPEIKCPERCLCEGTVVRCINVGLTAVPVDDIPE TVTELYLNLNKIRLIPTSIKRFTKLEKLDLSNNLIATLQDNIFANFTRLSTLLLAYNKLR CLPPRGFSGLKNLRILSLHSNEISTVQHGTFDDLIALSHAGFGSNPWYCDCNLAWFNEWI NKD---YLEPGIAQCSGPSAVAGRVLLTTPIASFVCNDLPLSKCKRRKSRRRGPLSIPIA SKCDPCLSTPCLHDGTCRLHPVEYYQCICPSGFKGKHCEMPVNACNLHPCRNGATCTG-- RDEISYTCTCPPGFSGYDCEINIDDCKMRPCRPDNATCIDGINTYTCKCPPGWSGDFCHI EIEDPCSENPCM---NEGQC--FPSLASDGQVEFRCECKIGFRG--------LNCSEEWD PCLDHKCENEAQCVMDGSNGAGYRCECSRGYR--GQYCEFIDGHTALIQQDDPCIGNDCE NGAQCYVEPGRASDFTCRCLPGYT-GNKCQMLTGVSFLRNGSYAELHKAVEDQEYLQITV EIATKELNGVILYAGESSQHITIELFAGHVRFSYDGINSAIYSEEI-------INDEEFH VIRLDIRTASVTMVIDDSRNYEAVSKKIVSTALPLYVGGIPANVLSNARRSWHIRNTTSF VGCLRNLNIDGEPVDFFTASQAGFSDLFQQDTGVRPGCSRDGLVSTCSDLTCKFGECVAN ENGGSQCSCMEGYSGIYCDIEDSEPTACSGNRCQHGMCVVNGENASS---YVCECDAGYG GEFCEIRDFCAGVD----CGDHGTCVP----HSSGHTCKCRMGY-----------SGRNC ASRIRRCSGT-KTRQFVQIT---------------VARSSSDESPTTSSDMTSSSSDTML CKSNKRITNLVCD----SSSCTRISRRTARRRARGSESGHFRATTLRGLGAIL------- -NEEPPAPTCCAPLRQK-------------------------------RKNIELLC---- ----EDGTRI-------TQQVTKVQSCGCQTCGQE
BMGE Cleaned alignment of selected proteins >sp|Q9UBM4|OPT_HUMAN Opticin OS=Homo sapiens OX=9606 GN=OPTC PE=1 SV=1 AFLSLLALVLQETGTASLPRKERKEEQMPREGDSFEVLPLRNDVLNPDNYGEVIDLSNYEELTDYGDQLPEVKVAPGTPSSNPTMTRPTLLSSQGLPTCLVCVCLGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALPVLPSGIEFLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGLSLRSVHLQNNLIETMCDPEEHKHTRRQLEDIRLDGNPINLSLFPSAYFPRLPI >tr|Q15JE7|Q15JE7_DANRE Opticin OS=Danio rerio OX=7955 GN=optc PE=1 SV=1 MLLYLVWILLGFSLGAPPT-------------------DLDLEAFGLENYD---DPDSWDLHYNYDDEHEEV--EEMTLPPRPTKSPVPLFGPDGMPTCLLCVCISGSVYCDDSDLTHIPPLPKETTHFYARFNKITEIKAADFINLNQLKRIDLSGNQIGKVNEDAFRSLLQLQDLMMADNNIQALPELPASLKHIDIRNNKLRSSGMHAEAFKEMKELQFLYLSHNKLDYIPVESLRVLHLQNNNIQSICNSHDKNYIRKALEDIRLDGNPVDINLYPQAYFPRLPV >NP_473417.2 opticin isoform 1 [Mus musculus] AFLSLLSLVLQKAETASLLGEREREEQSPEEGDTYASLYVGNHTLSIEDYNEVIDLSNYEELADYGDQIPEAKIAQKTLSPNLTMAVPTLLNSQGLPTCLVCVCLGSSVYCDDADLENIPPLPQMTTYLYARFNHISHIQAGDFKGLTKLRRIDLSGNSISSIHNDALRLLPALQDLILPENQLAALPVLPSGIEFLDVRLNRLQSSGIQPEAFVALKKLQFLYLANNMLDSIPGLSLRSLHLQNNMIETMCDTGEHRHERRQLEDIRLDGNPINLSLFPEAYFPRLPV >XP_038946639.1 opticin isoform X1 [Rattus norvegicus] TFLSLLTLVLQEAGTASLLGEREREEKSPEEADTYASLHVGNYSLSLEDYSEVIDLSSYEELADYGDQIPEAKTVPRTLPSRLTMAGPTLLNSQGLPTCLVCVCLGSSVYCDDANLENIPPLPQMTTYLYARFNHISHIQAGDFKGMTKLRRIDLSSNSISSIHNDALRLLPALQDLILPENQLAALPVLPSGLEFLDVRLNRLQSSGIQPEAFVTLEKLQFLYLADNLLDSIPGLSLRSLHLQSSSVHS-HALHTHLPTQNSRRTMKGRGG--RGGGRGTEAGGRVGR >NP_989804.1 opticin precursor [Gallus gallus] AWVGIASLCLGAAWAVPAKKERKKVEKLKPDLVLYENLDLDNYDVTLDNYGDIMDLNNYEELYDYGDLAPKIEVAPTPKLQPPDTTNPIPPGPGGVPSCLPCLCIRTSVYCDDTDLEHIPPLPPDTTYLYARFNRISAIRAGDFMGLKKLKRIDLTSNSISWADVDAFRFLPSLQELILPENRLTALPELPRSIIRLDARLNRIPSAGLRPEAFQDLTQLQFLHLSDNQLDYIPAESLRSLHLQNNNIQTMCNSQDQSHVRRALEDIRLDGNPINLSLFPNAYFPRLPT >NP_999173.1 opticin precursor [Sus scrofa] ALLSLLALMLQEAGTASLPEKEREEDRLHRESDSSTALHLGDYTLSPDSHDGVLDLSNYEELMDYGDQLPKVKGPPRTPPSSPTVARPTPPGSPGLPTCLVCVCLGSSVYCDDTDLENIPPLPQTTTYLYARFNRINHIRAGDFKGLTKLKRIDLSSNFISSIDDDALLLLPDLQDLILIENQLAALPTLPTAIEVLDVRLNRLRSSGIQPGAFRALEKLQFLYLADNLLDSIPGLSLRSLHLQNNMIETLCDPEEHKHTRRQLEDIRLDGNPINLSLFPSAYFPRLPI >NP_001003056.1 opticin precursor [Canis lupus familiaris] AFLSLLALVLLEAGTASLPKERKRRDEMHGEGDSYVV--LGNYVLGPDNYDEVIDLSDYEGLMDYGDQLPEAKVTPRTLSLKPTMIRPTVLGSPGLPTCLICVCLGSSVYCDDADLENIPPLPKTTTYLYARFNRIRRIRAGDFKGLTKLKRIDLSSNSISSIDDDALRLLPALQDLILPENQLAALPALPPAIEVLDARHNQLQSSGIQPEALRALEKLQFLYLADNLLDSIPGPSLRSLHLQNNLIETMCDPEEHKHSRRWLEDIRLDGNPINLGLFPSAYFPRLPT >NP_991339.1 opticin precursor [Bos taurus] ALLSLLILMLQEARTASLSEER--------EGDPYAILHLGDYVLSLDNYDEVIDPSNYDELIDYGDQLPQVKGAARTLPSNPTTARPPLLAAPGLPTCLICVCLGSSVYCDDADLENIPPLPQTTAYLYARFNRISHIRAGDFKGLTKLKRIDLSGNSISSIDDKALRLLPALRDLILPENKLVALPTLPTSIEVLDVRMNRLQSSGIQPEAFRALEKLQFLYLADNLLDAIPPLSLRSLHLQNNMIETMCDAEEHRHTRRPLEDIRLDGNPINLSLFPSAYFPRLPT >XP_016791796.1 opticin [Pan troglodytes] AFLSLLALVLQETGTASLPRKERKEEQMPREGDSFEVLPLRNDVLNPDNYGEVIDLSNYEELTDYGDQLPEVKMAPGTPSSNPTMTRPTLLSSQGLPTCLVCVCLGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLLLPENQLEALPVLPSGIEFLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGLSLRSVHLQNNLIETMCDPEEHKHTRRQLEDIRLDGNPINLSLFPSAYFPRLPI >XP_017203333.1 PREDICTED: opticin [Oryctolagus cuniculus] AFLSLLALVLQ-------------------EGDPHTALPLDDYGLSPDDYGEVLDLGNYEEPTDYGEQPLEVKAALRTPSSSPTVPGP-----PSLPTCLVCVCLGSSVYCDDADLESIPPLPKTTTYLYARFNRIRRVRAGDFQGLAKLKRIDLSSNVISYIESDALRALPALQDLLLPENQLAALPALPSSVQLLDARLNRLQSSGIQPGAFRALEKLQFLYLADNLLDSVPGLSLRSLHLQNNAIGTLCDAEEHRHTRRPLEDVRLDGNPVNLSLFPDAYFPRLPT >XP_002809624.1 opticin [Pongo abelii] AFLSLLALVLQETGTASLPRKERKEEQMPREGDSFEVLPLRNDVLNPDNYGEVIDLSNYEELTDYGDQLPEVKVAPGTPSSNPTMTRPTLLSSQGLPTCLVCVCLGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENKLEALPVLPSGIEILDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGLSLRSVHLQNNLIETMCDPEEHKHTRRQLEDIRLDGNPINLSLFPSAYFPRLPI >XP_003203890.1 opticin [Meleagris gallopavo] AWVGIASLCLGATWAVPAKKERKKVEKPKPDLVLNENLDLDNYDMTLDSYGDIMDLNNYEELYDYGDLAPKVEVAPTPKLKPLATTNPTPLGLNGLPSCLRCLCIRTSVYCDDTDLEHIPPLPPDTTYLYARFNRIGAIRAGDFMGLKKLKRIDLTSNSISWADVDAFRLLPSLQELILPENRLTALPELPRSIVRLDARLNRIPSAGLRPEAFQDLTQLQFLHLSDNQLDYIPAESLRSLHLQNNNIQTMCNSQDQSHIRRALEDIRLDGNPINLSLFPNAYFPRLPT >XP_003823034.1 opticin isoform X1 [Pan paniscus] AFLSLLALVLQETGTASLPRKERKEEQMPREGDSFEVLPLRNDVLNPDNYGEVIDLSNYEELTDYGDQLPEVKMAPGTPSSNPTMTRPTLLSSQGLPTCLVCVCLGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALPVLPSGIEFLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGLSLRSVHLQNNLIETMCDPEEHKHTRRQLEDIRLDGNPINLSLFPSAYFPRLPI >XP_006942942.2 opticin isoform X1 [Felis catus] AFQILLALVLLEAGTASPPKGRKRRDPTNEEGDSYAVLNLGNYVPDLDNYDEVIDLSDYEGLMDYGDQLPEVKANPRTLSSKPTMTKPTLPGSPGLPTCLVCVCLGSSVYCDDADLESIPPLPKTTTYLYARFNRISRIRAGDFKGLTKLKKIDLSSNSISSIDDDALRLLPALRDLILPENQLAALPVLPAGIEVLDVRLNRLQSSGIQPEAFRGLERLQFLYLADNLLDSIPGPSLRSLHLQNNMIETMCDTEEHKHSRRRLEDIRLDGNPINLGFFPSAYFPRLPT >XP_027831905.1 opticin [Ovis aries] ALLSLLILMLQEAGTAPLSKEERGEEQPYGEGDSYAILHLGDYVLSLDNYEEVIDPSNYDELTDYGDQLPQVKGAARTLPSNPTTARPPLLAAPGLPTCLICVCLGSSVYCDDADLENIPPLPQTTAYLYARFNRISHIRAGDFKGLTKLKRIDLSGNSISSIDDKALRLLPALRDLILSENKLVALPALPTSIEVLDVRMNRLQSSGIQPEAFRALEKLQFLYLADNLLDAIPWLSLRSLHLQNNMIETMCDAEEHRYTRRQLEDIRLDGNPINLSRFPSAYFPRLPT >XP_018884560.1 opticin [Gorilla gorilla gorilla] AFLSLLALVLQETGTASLPRKERKEEQMPREGDSFEVLPLRNDVLNPDNYGEVIDLSNYEELTDYGDQLPEVKVAPGTPSSNPTMTRPTLLSSQGLPTCLVCVCLGSSVYCDDIDLEDIPPLPRRTAYLYARFNRISRIRAEDFKGLTKLKRIDLSNNLISSIDNDAFRLLHALQDLILPENQLEALPVLPSGIEFLDVRLNRLQSSGIQPAAFRAMEKLQFLYLSDNLLDSIPGLSLRAVHLQNNLIETMCDPEEHKHTRRQLEDIRLDGNPINLSLFPSAYFPRLPI >XP_021154000.1 opticin [Columba livia] AWLGIASLCLGTAWAVPA-KERRKAEKPKAHLALYENLDLDNYDLTLDNYGEILDLSNYEELYDYGDLAPKIEVAETPKLQLLSTAGPV---PIALPSCQLCLCIGTSVYCDDADLEHIPPLPPETTYLYARFNRIGTIQASDFMGLKKLKLIDLSSNSITRADADAFRLLPSLQELILPENRLTALPELPRSIVRLDARLNSIPSTGLRPDAFRDLKQLQFLHLSDNQLDYIPAESLRSLHLQNNNIQTMCDSQDHSQVRRALEDIRLDGNPINLSLFPNAYFPRLPT >KAB0342281.1 hypothetical protein FD754_019207 [Muntiacus muntjak] ALLSLLILMLQEAGTASLSKEEREEDQPYGEGDSYAILHLGDYVLSLDNYDEVIDPSNYDELTDYRDQLPQVKGVARTLPSNPTMARPPLLAAPGLPTCLICVCLGSSVYCDDTDLENIPPLPQTTAYLYARFNRISHIRAGDFKGLTKLKRIDLSGNSISSIDDKALRLLPALRDLILPENKLAALPVLPTSIEVLDVRMNRLQSSGIQPEAFRALEKLQFLYLADNLLDAIPRLSLRSLHLQNNMIETMCDAKEHRHTRRQLEDIRLDGNPINLSLFPSAYFPRLPT >KAB0376678.1 hypothetical protein FD755_011122 [Muntiacus reevesi] ALLSLLILMLQEAGTASLSKEKREGDQPYGEGDSYAVLHLGDYVLSLDNYDEVIDPSNYDELTDYRDQLPQVKGVARTLPSNPTMARPPLLAAPGLPTCLICVCLGSSVYCDDTDLENIPPLPQTTAYLYARFNRISHIRAGDFKGLTKLKRIDLSGNSISSIDDKALRLLPALRDLILPENKLAALPVLPTSIEVLDVRMNRLQSSGIQPEAFRALEKLQFLYLADNLLDAIPRLSLRSLHLQNNMIETMCDAEEHRHTRRQLEDVRLDGNPINLSLFPSAYFPRLPT >KAF4018212.1 hypothetical protein G4228_010223 [Cervus hanglu yarkandensis] ALLSLLILMLQEAGTASLSKEEREEDQPYGEGDSYAVLHLGDYVLSLDNYDEVIDPSNYDELTDYGDQLPQVKGVARTLPSNPTMGRPPLLAAPGLPTCLICVCLGSSVYCDDTDLENIPPLPQTTAYLYARFNRISHIRAGDFKGLTKLKRIDLSGNSISSIDDKALRLLPALRDLILPENKLAALPALPTSIEVLDVRMNRLQSSGIQPEAFRALEKLQFLYLADNLLDAIPRLSLRSLHLQNNMIETMCDAEEHRHTRRQLEDVRLDGNPINLSLFPSAYFPRLPT >XP_043341198.1 opticin [Cervus canadensis] ALLSLLILMLQEAGTASLSKEEREEDQPYGEGDSYAVLHLGDYVLSLDNYDEVIDPSNYDKLTDYGDQLPQVKGVARTLPSNPTMGRPPLLAAPGLPTCLICVCLGSSVYCDDTDLENIPPLPQTTAYLYARFNRISHIRAGDFKGLTKLKRIDLSGNSISSIDDKALRLLPALRDLILPENKLAALPALPTSIEVLDVRMNRLQSSGIQPEAFRALEKLQFLYLADNLLDAIPRLSLRSLHLQNNMIETMCDAEEHRHTRRQLEDVRLDGNPINLSLFPSAYFPRLPT >OWK08495.1 OPTC [Cervus elaphus hippelaphus] ALLSLLILMLQEAGTASLSKEEREEDQPYGEGDSYAVLHLGDYVLSLDNYDEVIDPSNYDKLTDYGDQLPQVKGVARTLPSNPTMGRPPLLAAPGLPTCLICVCLGSSVYCDDTELENIPPLPQTTAYLYARFNRISHIRAGDFKGLTKLKRIDLSGNSISSIDDKALRLLPALRDLILPENKLTALPMLPTSIEVLDVRMNRLQSSGIQPEAFRALEKLQFLYLADNLLDAIPRLSLRSLHLQVSGCSGN--VERHRRWRSDCRE------P------PSAVVRH--- >XP_018104794.1 opticin [Xenopus laevis] IALCVSGIALCSAPPSPGASRNNK-----EKHRSGENIKLVDYNI---NYEESIDIRKYEELHDYYDHEPK-EVNPITL---PSIPKPSLFGSMGLPICLVCACIGTSVYCDDVDLNGIPPLPKDTAYLYARFNRITRINNNDFKGLNKLKRVDLSSNFLSKIDDDAIHFLPSLQELILSENQLKALPELPSSLTRLDVQYNQLQSSGIQTDAFKDLTSLEYLYLSNNKLDYIPVYSLRSLHLQNNNIQTMCESRDLTFIRRNLEDIRMDDNPINLSKFVHGYFVRLPT >XP_030296407.1 epiphycan isoform X3 [Sparus aurata] VRLVLGLLVLKAVVAGPRFSRQVD----------LDSYDSANYDVDLDNLNSEQDIYDYDDGLTIDD--PQIEIEEEEMPPQLIPQGSGLMGPDGMPTCLLCTCLGGSVYCDDLKLDSVPPLPKDTTHFYARYNRITKINKSDFAFLNKLKRIDLTANEITSVDDRAFMALPELEELVIRENHISQLPALPETMTLIDASHNNIGTKGIHNEAFKDMTSLLYLYLTDNHVDYIPVDSLRSLHLQRNNIQMMCNLKDFNYIRNALEDIRLDGNPINLSRTPQAYIPRIPI >XP_015815457.1 PREDICTED: dentin sialophosphoprotein-like [Nothobranchius furzeri] VRLVLGLFVLKAAIASPRFSRQVD----------LDTYDLANYDEEEDNFDLDGESYDYDEELTTDE--SETETEEEELPPQLIPQGSGLMGPDGMPVCLLCTCLGGSVYCDDLKLDSVPPLPKDTTHFYARYNKITKINKSDFANMNKLKRIDLTANEITAIDDKAFMGLPALEQLIIRENHVSQLPALPETMTLIDGSHNNIGSRGIHKEAFKDMTSLQFLYLTDNNIDYIPVDSLRSIHLQRNNIQMMCNLNDFNYIRNALEDIRLDGNPINLSKTPQAYIPRIPV >XP_004083110.1 aggrecan core protein [Oryzias latipes] VRLVLGLFVLKAAVASPRFSRQAN----------LDIYDDANYDEELNNVESE-DTYDYEDGLTIDE--PEIEIEEEELTPQPIPQGSGLMGPEGMPTCLLCTCLGTSVYCDDLKLDSVPPLPKETTHFYARYNKITKINKSDFAFMNKLKRVDLTANEITAIDGTAFIGLPELEELVVRQNHLTQLPALPETMTLIDASHNSIGSKGIHKEAFKDMTGLLFLYLTDNNIDYIPVESLRSLHLQRNNIQMMCNLNDFNYIRNALEDIRLDGNPINLSKTPQAYVPRIPI >XP_040200080.1 epiphycan [Rana temporaria] ANIFLGLLIIKAVVSAPPT-------------------DSVNYDTAAYEVDLLYNLYDYDENTNIDQ--GEIEISTPKLIDGSSPQGPL---PEGVSTCILCGCIRTTVYCDDHNLDAVPPLPKDTTHVYLRFNRISKINKNDFSYLSKLQKIDLTSNIISDIDEDAFRSLSQLDELILLDNNIRQLPELPHSVSFLDVSKNRLGRKGIKQEAFKDLNDLRLLYLNNNNLDHIPIDSLQALHLQDNNIQEMCNMKDFTYARRSLEDIRLDGNPINLSKTPQAFMPRIPV >XP_005690430.1 PREDICTED: opticin [Capra hircus] ALLSLLILMLQEAGTASLSKEERGEEQPYGEGDSYAILHLGDYVLSLDNYEEVIDPSNYDELTDYGDQLPQVKGAARTLPSNPTTARPPLLAAPGLPTCLICVCLGSSVYCDDADLENIPPLPQTTAYLYARFNRISHIRAGDFKGLTKLKRIDLSGNSISAIDDKALRLLPALRDLILPENQLVALPALPTSIEVLDVRMNRLQSSGIQPEAFRALEKLQFLYLADNLLDAIPRLSLRSLHLQNNMIETMCDAEEHRYTRRQLEDIRLDGNPINLSLFPSAYFPRLPT >XP_006025086.1 opticin [Alligator sinensis] VLLGMITLALAALALAVPLGEGKKTEKPSTDLTIYESLNLDNYDLSLNNYGDIIDLSNYDELYDYGDLAPKIEVTPRKELPMSTTAKPVLLGFIGLSTCLVCVCIGTSVYCDDAGLEHIPALPLETMYLYARFNSIGQIRARDFAGLKKLKRIDLTSNYISSVEEGSFRQLTSLQELILPENRLTVLPDLPSSIIRLDARFNRIQSSGLRPEAFRELKKLQFLHLSDNELDYIPAESLRSLHLQNNNIQTMCDSQDLTHIRRALEDIRLDGNPINLSLFPSAYFPRLPT >XP_019347037.1 PREDICTED: opticin [Alligator mississippiensis] VLLGMITLMLAALALAVPLGEGKKTEKPSADLTIYESLNLDSYDLSLNNYGDIIDLSNYDELYDYGDLAPKIEVAPRKQPPMPTTAKPVLLGFIGLSTCLVCVCIGTSVYCDDAGLEHIPALPLETMYLYARFNSIGQIRARDFAGLKKLKRIDLTSNYISSVEEGSFRQLTSLQELILPENRLTALPDLPSSIIRLDARFNRIQSSGLRPEAFRELKKLQFLHLSDNELDYIPAESLRSLHLQNNNIQTMCDSQDLTHIRRALEDIRLDGNPINLSLFPSAYFPRLPT >XP_020753367.1 opticin [Odocoileus virginianus texanus] ALLSLLILMLQEAGTASLSKEEREEDQPYGEGDSYAILHLGDYVLSLDNYDEIIDPSNYDELTDYGDQLPQVKGVARTLPSNPMMARPPLLAAPGLPTCLICVCLGSSVYCDDTDLENIPPLPQTTAYLYARFNRISHIRAGDFKGLTKLKRIDLSGNSISSIDDKALRLLPALRDLILPENKLTALPALPTSIEVLDVRMNRLQSSGIQPEAFRALEKLQFLYLADNLLDAIPRLSLRSLHLQNNMIETMCDAEEHRHTRRQLEDVRLDGNPINLSLFPSAYFPRLPT >XP_031550322.1 uncharacterized protein LOC116287775 isoform X1 [Actinia tenebrosa] --------------------NRRK---------------------------------------------PVMHSGTVYLVPNPVVSDNC-----GCKNCVRTDCLHNSWMID------VPPLPRTMGTLIFKSNAVKTIKTSSFQSYKYLKNLDLANNRIESIENRSFQYQEHLEKLDLMNNRLTNLTADMRSLEKLDLQNNRI--SSLSRGVFRSMTELKYLDLHDNQISSIEDMSLRTIDLSFNNIESICSP--------LLETLHLNGNGLKDSISSKAFFPGIPV >XP_039262601.1 slit homolog 2 protein-like isoform X2 [Styela clava] TLLAVVGLGIACPSKCSCTEDTMQIEKIELQGDENQIVSIEKNSFGENNLLEILRLNNNELTILPENLFSKLRAKLTTLPSEWLISRPSLQGMEQKPKCSMCKCSNGIVDCRDKGLKSLPVMPADVTEIRLEQNMIEVIPARAFARYRKLKRIDLSNNLISEVSEDSFQGLKHLNSLIMYENKITSLPKGIGNLQLLLLNANKL--SCLRHDTFDGLVSLKLLSLYDNKLQIISKRNLRTLMARNNRLKCICSTEEKSQIPETVTELYLNLNKIRLCLPPRGFSPPAPT
PhyML tree of selected proteins (tr_Q15JE7_Q15JE7_DANRE_Opticin_OS_Danio_rerio_OX_7955_GN_optc_PE_1_SV_1:0.4835274,(XP_040200080_1_epiphycan__Rana_temporaria_:0.5090797,(XP_030296407_1_epiphycan_isoform_X3__Sparus_aurata_:0.05709542,(XP_015815457_1_PREDICTED__dentin_sialophosphoprotein_like__Nothobranchius_furzeri_:0.10956275,XP_004083110_1_aggrecan_core_protein__Oryzias_latipes_:0.10472386):0.04748224):0.33984103):0.38341895,(XP_018104794_1_opticin__Xenopus_laevis_:0.50724232,((((XP_021154000_1_opticin__Columba_livia_:0.07907218,(NP_989804_1_opticin_precursor__Gallus_gallus_:0.03948263,XP_003203890_1_opticin__Meleagris_gallopavo_:0.03736377):0.09333819):0.16223763,(XP_006025086_1_opticin__Alligator_sinensis_:0.02420954,XP_019347037_1_PREDICTED__opticin__Alligator_mississippiensis_:0.00454363):0.18156962):0.07091103,(XP_031550322_1_uncharacterized_protein_LOC116287775_isoform_X1__Actinia_tenebrosa_:1.59328723,XP_039262601_1_slit_homolog_2_protein_like_isoform_X2__Styela_clava_:1.6964238):0.80213452):0.06310535,(((NP_991339_1_opticin_precursor__Bos_taurus_:0.03160444,(XP_005690430_1_PREDICTED__opticin__Capra_hircus_:0.0072112,XP_027831905_1_opticin__Ovis_aries_:0.01463443):0.00943882):0.00977992,((XP_020753367_1_opticin__Odocoileus_virginianus_texanus_:0.011103,(KAF4018212_1_hypothetical_protein_G4228_010223__Cervus_hanglu_yarkandensis_:0.00000001,(OWK08495_1_OPTC__Cervus_elaphus_hippelaphus_:0.09715452,XP_043341198_1_opticin__Cervus_canadensis_:0.00000001):0.00359196):0.00689423):0.00000001,(KAB0376678_1_hypothetical_protein_FD755_011122__Muntiacus_reevesi_:0.01053314,KAB0342281_1_hypothetical_protein_FD754_019207__Muntiacus_muntjak_:0.00743653):0.00721053):0.01432504):0.11169148,(((NP_001003056_1_opticin_precursor__Canis_lupus_familiaris_:0.07132501,XP_006942942_2_opticin_isoform_X1__Felis_catus_:0.09571083):0.06435593,((NP_999173_1_opticin_precursor__Sus_scrofa_:0.12154068,XP_017203333_1_PREDICTED__opticin__Oryctolagus_cuniculus_:0.2237451):0.04095039,(XP_002809624_1_opticin__Pongo_abelii_:0.00387423,(sp_Q9UBM4_OPT_HUMAN_Opticin_OS_Homo_sapiens_OX_9606_GN_OPTC_PE_1_SV_1:0.00000001,(XP_018884560_1_opticin__Gorilla_gorilla_gorilla_:0.0035769,(XP_016791796_1_opticin__Pan_troglodytes_:0.00357675,XP_003823034_1_opticin_isoform_X1__Pan_paniscus_:0.00000001):0.00360129):0.00000001):0.00333842):0.14430614):0.02796741):0.01734785,(XP_038946639_1_opticin_isoform_X1__Rattus_norvegicus_:0.24476303,NP_473417_2_opticin_isoform_1__Mus_musculus_:0.0632179):0.14165764):0.01703343):0.32912641):0.1134575):0.22832944);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)