PB0173

DATABASE

Click here to access PB0173 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0173	P13497	Bone morphogenetic protein 1	BMP1	OI13, PCOLC, PCP, PCP2, TLD	Homo_sapiens	Additional substrates include matricellular thrombospondin-1/THBS1 whose cleavage leads to cell adhesion disruption and TGF-beta activation (PubMed:32636307).

Domains

Gene Ontology

PF00431 (5_CUB) PF01400 (Astacin) PF07645 (EGF_CA)

GO:0061036 (acts upstream of or within) positive regulation of cartilage development GO:0004222 (enables) metalloendopeptidase activity GO:0004252 (enables) serine-type endopeptidase activity GO:0005125 (enables) cytokine activity GO:0005509 (enables) calcium ion binding GO:0005515 (enables) protein binding GO:0008083 (enables) growth factor activity GO:0008233 (enables) peptidase activity GO:0008237 (enables) metallopeptidase activity GO:0008270 (enables) zinc ion binding GO:0016787 (enables) hydrolase activity GO:0042802 (enables) identical protein binding GO:0046872 (enables) metal ion binding GO:0001501 (involved in) skeletal system development GO:0001502 (involved in) cartilage condensation GO:0001503 (involved in) ossification GO:0006508 (involved in) proteolysis GO:0007165 (involved in) signal transduction GO:0007275 (involved in) multicellular organism development GO:0009953 (involved in) dorsal/ventral pattern formation GO:0016485 (involved in) protein processing GO:0030154 (involved in) cell differentiation GO:0030199 (involved in) collagen fibril organization GO:0051216 (involved in) cartilage development GO:0005576 (located in) extracellular region GO:0005615 (located in) extracellular space GO:0005794 (located in) Golgi apparatus GO:0031982 (located in) vesicle

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|P13497|BMP1_HUMAN Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 PE=1 SV=2 MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN IQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIG QRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKI ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSF EIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF AVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNG SITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSK LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVN TFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISST PGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLR FYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGY GVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHS DDTITKKGFHLRYTSTKFQDTLHSRK >sp|P13497-2|BMP1_HUMAN Isoform BMP1-1 of Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN IQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIG QRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKI ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSF EIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF AVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNG SITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSK LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSEKRPALQPPRGRPHQLKF RVQKRNRTPQ >sp|P13497-3|BMP1_HUMAN Isoform BMP1-4 of Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN IQPGVLHSSLLLLSCGSRNGASFPCSLESSTHQALCWTGLFLRPSPFPRLPLAAPRTLRA GV >sp|P13497-4|BMP1_HUMAN Isoform BMP1-5 of Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN IQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIG QRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKI ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSF EIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF AVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEGCYDLQVGKPLL WDRHCFRLSTHGPEMLGTALRG >sp|P13497-5|BMP1_HUMAN Isoform BMP1-6 of Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN IQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIG QRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKI ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSF EIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF AVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNG SITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSK LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSGGELFGLLGHPPRRP >sp|P13497-6|BMP1_HUMAN Isoform BMP1-7 of Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN IQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIG QRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKI ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSF EIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF AVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNG SITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSK LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSVLEGAGDRHSHLSGLELL LCPHALVDTVPAPPSALHGDTHAHTHTHVHTHCPIAQETCRGPPLGASRLSPQGPGHLTL APQEGSYLDFWDTHRGDPKPRRRRKSLKTFSLTPATFRGIWAL >tr|F1REM3|F1REM3_DANRE Metalloendopeptidase OS=Danio rerio OX=7955 GN=bmp1a PE=4 SV=2 MELAARCALLLSSFSLLAALDLDAIEPGYYVETSSPSDLIDYKDPCKAVAYLGDIALDEE DMRMFTVDRIVNLADRTVTILNHTNTGSLSNETSVNTTASSRGSHRRRRAATSRPERVWP EGVIPYVISGNFSGSQRAIFRQAMRHWEKHTCVTFIERTTEESYIVFTYRPCGCCSYVGR RGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDEHVSIIRDNIQPGQEYNFLK MEPGEVDSLGEVYDFDSIMHYARNTFSRGIFLDTILPRYDVNGVRPPIGQRTRLSKGDIA QARKLYKCPRCGDSLQESSGNFSSPGYPNGYSAYMHCIWRISVTPGEKIILNFTSMDLYR SHLCWYDHVEIRDGYWRKAPLKGRFCGDKLPDPIISTDSRLWIEFRSSSNWVGKGFSAVY EAICGGEVKKDNGQIQSPNYPDDYRPNKVCVWKITVAQGYHVGLTFQSFEIERHDNCAYD YLEVRDGNSESSPLLGRFCGYDKPDDIKSSSNQLWMKFVSDGSVNKAGFAANFFKEMDEC SRPDNGRCEQRCVNTLGSYKCACDPGYELAADKRSCEAACGGFITKLNGSITSPGWPKEY PPNKNCIWQLVAPTQYRITLLFDVFETEGNDVCKYDFVEVRSGLSADSRLHGKFCGAEKP EAITSQYNNMRIEFKSDNTVSKKGFKAQFFSDKDECSKENGGCQHECVNTFGSYSCQCRS GFVLHENKHDCKEAGCDHVVNSVSGTITSPNWPDKYPSKKACTWALSTTPGHRIKIAFNE IDMEPHLECAYDHIEIYDGRDSKAQSLGRYCGTKKPQPIISTGNKMFIRFFSDNSVQKKG FEASHTAECGGRLKAEVKTKDLYSHAQFGDNNYPGASDCQWVITAEKGYGVELIFQTFEI EEEADCGYDYMELFDGADTKSPRLGRYCGSGPPEEIYSAGDSIVIKFHSDDTINKKGFHV RYTSTKFQDTLHSRKK
Selected proteins from model organisms >sp|P13497|BMP1_HUMAN Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 PE=1 SV=2 MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN IQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIG QRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKI ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSF EIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF AVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNG SITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSK LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVN TFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISST PGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLR FYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGY GVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHS DDTITKKGFHLRYTSTKFQDTLHSRK >sp|P13497-2|BMP1_HUMAN Isoform BMP1-1 of Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN IQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIG QRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKI ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSF EIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF AVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNG SITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSK LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSEKRPALQPPRGRPHQLKF RVQKRNRTPQ >sp|P13497-3|BMP1_HUMAN Isoform BMP1-4 of Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN IQPGVLHSSLLLLSCGSRNGASFPCSLESSTHQALCWTGLFLRPSPFPRLPLAAPRTLRA GV >sp|P13497-4|BMP1_HUMAN Isoform BMP1-5 of Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN IQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIG QRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKI ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSF EIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF AVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEGCYDLQVGKPLL WDRHCFRLSTHGPEMLGTALRG >sp|P13497-5|BMP1_HUMAN Isoform BMP1-6 of Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN IQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIG QRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKI ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSF EIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF AVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNG SITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSK LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSGGELFGLLGHPPRRP >sp|P13497-6|BMP1_HUMAN Isoform BMP1-7 of Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN IQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIG QRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKI ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSF EIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF AVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNG SITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSK LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSVLEGAGDRHSHLSGLELL LCPHALVDTVPAPPSALHGDTHAHTHTHVHTHCPIAQETCRGPPLGASRLSPQGPGHLTL APQEGSYLDFWDTHRGDPKPRRRRKSLKTFSLTPATFRGIWAL >tr|F1REM3|F1REM3_DANRE Metalloendopeptidase OS=Danio rerio OX=7955 GN=bmp1a PE=4 SV=2 MELAARCALLLSSFSLLAALDLDAIEPGYYVETSSPSDLIDYKDPCKAVAYLGDIALDEE DMRMFTVDRIVNLADRTVTILNHTNTGSLSNETSVNTTASSRGSHRRRRAATSRPERVWP EGVIPYVISGNFSGSQRAIFRQAMRHWEKHTCVTFIERTTEESYIVFTYRPCGCCSYVGR RGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDEHVSIIRDNIQPGQEYNFLK MEPGEVDSLGEVYDFDSIMHYARNTFSRGIFLDTILPRYDVNGVRPPIGQRTRLSKGDIA QARKLYKCPRCGDSLQESSGNFSSPGYPNGYSAYMHCIWRISVTPGEKIILNFTSMDLYR SHLCWYDHVEIRDGYWRKAPLKGRFCGDKLPDPIISTDSRLWIEFRSSSNWVGKGFSAVY EAICGGEVKKDNGQIQSPNYPDDYRPNKVCVWKITVAQGYHVGLTFQSFEIERHDNCAYD YLEVRDGNSESSPLLGRFCGYDKPDDIKSSSNQLWMKFVSDGSVNKAGFAANFFKEMDEC SRPDNGRCEQRCVNTLGSYKCACDPGYELAADKRSCEAACGGFITKLNGSITSPGWPKEY PPNKNCIWQLVAPTQYRITLLFDVFETEGNDVCKYDFVEVRSGLSADSRLHGKFCGAEKP EAITSQYNNMRIEFKSDNTVSKKGFKAQFFSDKDECSKENGGCQHECVNTFGSYSCQCRS GFVLHENKHDCKEAGCDHVVNSVSGTITSPNWPDKYPSKKACTWALSTTPGHRIKIAFNE IDMEPHLECAYDHIEIYDGRDSKAQSLGRYCGTKKPQPIISTGNKMFIRFFSDNSVQKKG FEASHTAECGGRLKAEVKTKDLYSHAQFGDNNYPGASDCQWVITAEKGYGVELIFQTFEI EEEADCGYDYMELFDGADTKSPRLGRYCGSGPPEEIYSAGDSIVIKFHSDDTINKKGFHV RYTSTKFQDTLHSRKK >NP_033885.2 bone morphogenetic protein 1 precursor [Mus musculus] MPGVARPPLPLLSLPLLLLLLLLPRAGRPLDLADYTYDLGEEDAPELLNYKDPCKAAAFLGDIALDEEDL RAFQVQQAAVLRQQTARRPSIKAAGNSSALGGQGTSGQPQRESRGRWRGRPRSRRAATSRPERVWPDGVI PFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNC DKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARN TFSRGIFLDTIVPKYEVNGVKPSIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAH MHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVE FRSSSNWVGKGFFAVYEAICGGDVKKDNGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERH DSCAYDYLEVRDGHSESSNLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPN RGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPT QYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKG FKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCEHKVTSTSGTITSPNWPD KYPSKKECTWAISSTPGHRVKLTFVEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGN RMFLRFYSDNSVQRKGFQASHSTECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELV FQTFEVEEETDCGYDYIELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTISKKGFHLRYTS TKFQDTLHSRK >NP_112613.1 bone morphogenetic protein 1 precursor [Rattus norvegicus] MPGVARPPLPLLSLPLLLLLLLPRAGRPLDLADYTYDLGEEDAPELLNYKDPCKAAAFLGDIALDEEDLR AFRVQQAAVLRQQTAQRSSIKAAGNSSALGRQSTSGQPQRGSRGRWRSRPRSRRAATSRPERVWPDGVIP FVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCD KFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNT FSRGIFLDTIVPKYEVNGVKPSIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHM HCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEF RSSSNWVGKGFFAVYEAICGGDVKKDNGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHD SCAYDYLEVRDGHSESSNLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNR GGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQ YRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGF KAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCEHKVTSTSGTITSPNWPDK YPSKKECTWAISSTPGHRVKLTFVEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGNR MFLRFYSDNSVQRKGFQASHSTECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVF QTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTISKKGFHLRYTST KFQDTLHSRK >XP_016814692.1 bone morphogenetic protein 1 isoform X1 [Pan troglodytes] MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDEEDLRAFQVQQ AADLRQHTARKSSIKAAVAGNTSTPSCQSTNGQPQRGACGRWRGRSRSRRAATSRPERVWPDGVIPFVIG GNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGI VVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRG IFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVW RISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAY DYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCE QRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRIS LQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF FSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSK KECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLR FYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFE VEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQD TLHSRK >XP_024852018.1 bone morphogenetic protein 1 isoform X1 [Bos taurus] MPGVARPPLPLLLWLLLLARPGRPLDLADYTYDLGEEDDAEPLNYKDPCKAAAFLGDIALDEEDLRAFQV QQAADLRQRATRRSSIKAAVSGNSSTLNSQNTSMKPQRRSRGRWKSRSRSRRAATSRPERVWPDGVIPFV IGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKF GIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFS RGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHC VWRISVTPGEKIILNFTSMDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRS SSNWVGKGFFAVYEAICGGDVKKDNGHIQSPNYPDDYRPSKVCVWRIQVSEGFHVGLTFQSFEIERHDSC AYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGG CEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYR ISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKA HFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSSSGTITSPNWPDKYP SKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVYDGRDSKAPVLGRFCGSKKPEPVLATGNRMF LRFYSDNSVQRKGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQT FEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKF QDTLHSRK >XP_020927995.1 LOW QUALITY PROTEIN: bone morphogenetic protein 1 [Sus scrofa] MPGVARPPLPLLLWLLLLARPGRPLDLADYTYDLGEEDDAEPLNYKDPCKAAAFLGDIALDEEDLRXFQV QQAADLRQRTTRKSSIKAAGNSSTLQCQSTRGQPQRRSHGKWRSRSRSRRAATSRPERVWPDGVIPFVIG GNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGI VVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRG IFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVW RISVTPGEKIILNFTSMDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSS NWVGKGFFAVYEAICGGDVKKDNGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAY DYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCE QRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRIS LQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF FSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSK KECTWAISSTPGHRVKLTFLEMDIESQPECAYDHLEVYDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLR FYSDNSVQRKGFQAAHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFE VEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQD TLHSRK >XP_002818918.1 bone morphogenetic protein 1 isoform X1 [Pongo abelii] MPGVARLLLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDEEDLRAFQVQQ AADLRQHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRRAATSRPERVWPDGVIPFVIG GNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGI VVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRG IFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVW RISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAY DYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCE QRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRIS LQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF FSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSK KECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLR FYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFE VEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQD TLHSRK >XP_038291401.1 bone morphogenetic protein 1 isoform X1 [Canis lupus familiaris] MPGVARLPLPLLLWLLLLPRPGRPLDLADYTYDLGEEDDSEPVNYKDPCKAAAFLGDIALDEEDLTAFQV QQVADLRQRTTHRSSIKTAVTYYYCGRLPTPGNSSAFNCQSTSGQLQRRSRGRWRSRSRSRRAATSRPER VWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQA ISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMELQEVESLGETYDFDS IMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEY PNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVST DSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKKDNGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQ SFEIERHDSCAYDYLEVRDGHSETSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEV DECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCI WQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSD NTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTI TSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVYDGRDAKAPVLGRFCGSKKPE PVLATGSRMFLRFYSDNSVQRKGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEE GYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKG FHLRYTSTKFQDTLHSRK >XP_003823651.1 bone morphogenetic protein 1 isoform X1 [Pan paniscus] MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDEEDLRAFQVQQ AADLRQHTARKSSIKAAVAGNTSTPSCQSTNGQPQRGACGRWRGRSRSRRAATSRPERVWPDGVIPFVIG GNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGI VVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRG IFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVW RISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAY DYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCE QRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRIS LQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF FSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSK KECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLR FYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFE VEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQD TLHSRK >XP_023108277.1 bone morphogenetic protein 1 isoform X2 [Felis catus] MPGVARLPLPLLLWLLLLARPGGPLDLADYTYDLGEEEDSEPVNYKDPCKAAAFLGDIALDEEDLRAFQV QQAEDLRQRATHRSSIKTTGNSSTPNCQSTSGQPQRRNRGRWRSRSRSRRAATSRPERVWPDGVIPFVIG GNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGI VVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMELQEVESLGETYDFDSIMHYARNTFSRG IFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVW RISVTPGEKIILNFTSMDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSS NWVGKGFFAVYEAICGGDVKKDNGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAY DYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCE QRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRIS LQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF FSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSK KECTWAISSTPGHRVKLTFVEMDIESQPECAYDHLEVYDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLR FYSDNSVQRKGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFE VEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRFTSTKFQD TLHSKK >XP_014948597.2 bone morphogenetic protein 1 isoform X3 [Ovis aries] MPGVARPPLPLLLWLLLLARPGRPLDLADYTYDLGEEDDAEPLNYKDPCKAAAFLGDIALDEEDLRAFQV QQAADLRQRATRRSSIKAAGTLVSGNSSTLNSQNASMKPQRRSRGRWKSRSRSRRAATSRPERVWPDGVI PFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNC DKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARN TFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAH MHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVE FRSSSNWVGKGFFAVYEAICGGDVKKDNGHIQSPNYPDDYRPSKVCVWRIQVSEGFHVGLTFQSFEIERH DSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPN RGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPT QYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKG FKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSSSGTITSPNWPD KYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVYDGRDAKAPVLGRFCGSKKPEPVLATGN RMFLRFYSDNSVQRKGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELV FQTFEVEEESDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTS TKFQDTLHSRK >XP_030869708.1 bone morphogenetic protein 1 isoform X1 [Gorilla gorilla gorilla] MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDEEDLRVFQVQQ AADLRQHTARKSSIKAAVPGNISTPSCQSTNGQPQRGACGRRRGRSRSRRAATSRPERVWPDGVIPFVIG GNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGI VVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRG IFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVW RISVTPGEKIILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAY DYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCE QRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRIS LQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHF FSDKDECSKDNGGCQQDCINTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSK KECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLR FYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFE VEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQD TLHSRK >XP_021154607.1 bone morphogenetic protein 1 [Columba livia] MQESRRAATSRPERVWPDGVIPYVISGNFSGSQRAIFRQAMRHWEKHTCVTFLERNDEDSYIVFTYRPCG CCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDDHVSIIRENIQPGQEYNFLKMEP EEVESLGETYDFDSIMHYARNTFSRGIFLDTILPKYDVNGVRPAIGQRTRLSKGDIAQARKLYRCPACGE TLQDSQGNFSSPEFPNGYSAHMHCVWRISVTPGEKIILNFTTLDLYRSRLCWYDYVEVRDGFWRKATLRG NQTGSSQPARRHCPHLLPNRGMLGVQAAGQGGFSSLTAICGGDVKKDNGHIQSPNYPDDYRPSKVCIWKI TVSEGFHVGLTFQSFEIERHDSCAYDYLEIRDGSSESSSLIGRYCGYDKPDDIKSTSNKLWMKFVSDGSI NKAGFAVNFFKEVDECSRPNNGGCEQRCINTLGSYKCACDPGYELASDKRRCEAACGGFLTKLNGSITSP GWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGAEKPDVIT SQYNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKNNGGCQHECLNSFGSYECQCRSGFVLHDNKHDCKEG GSAPRFCGAKEPEPLISSSNKMFLKFVSDNSVQKKGFEATHATVCGGQVHAEVKTKDLYSHAQFGDNNYP GGSDCEWVIMAEEGYGVELIFQTFEIEEEADCGYDYMELFDGYDGTAPRLGRFCGSGPPEEIYSAGDSVM IRFHSDDTINKKGFHLRYTSTKFQDTLHTKK >XP_017907774.1 PREDICTED: bone morphogenetic protein 1 isoform X1 [Capra hircus] MPGVARPPLPLLLWLLLLARPGRPLDLADYTYDLGEEDDAEPLNYKDPCKAAAFLGDIALDEEDLRAFQV QQAADLRQRATRRSSIKAAGTLVSGNSSTVNSQNASMKPQRRSRGRWKSRSRSRRAATSRPERVWPDGVI PFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNC DKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARN TFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAH MHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVE FRSSSNWVGKGFFAVYEAICGGDVKKDNGHIQSPNYPDDYRPSKVCVWRIQVSEGFHVGLTFQSFEIERH DSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPN RGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPT QYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKG FKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSSSGTITSPNWPD KYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVYDGRDAKAPVLGRFCGSKKPEPVLATSN RMFLRFYSDNSVQRKGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELV FQTFEVEEESDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTS TKFQDTLHSRK >XP_025066133.1 bone morphogenetic protein 1 [Alligator sinensis] MAGDPERPVELSKLLGGYGGYDTHDDIETASDLLWMRLVSDSSINKATASFSVTFKVTTEAASLGGKGAL HWDLLWIMRCLLLTKLNSIITSSRCLKEYLLNKNSVFLGDIALDEEDLRMFQADRITDLTRHTMLRVATN SSGSNTNNTRLRPRRHRKRHGWLVRQRSRSRRAATSRPERVWPDGVIPYVISGNFSGTQRAIFRQAMRHW EKFTCVTFLERTEEDSYIIFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRP DRDDHVAIIKENIQLGQEYNFLKMEPEEVESLGETYDFDSIMHYARNTFSRGIFLDTILPKYEVQGLRPS IGQRTRLSKGDISQARKLYRCPDCGETLQESQGNFSSPDFPNGYAAHKHCVWRISVTPGEKIILNFTTLD IYRSRLCWYDYVEVRDGFWRKATLRGRFCGNKLPEPIISTDSRLWIEFRSSSNWVGKGFFAAYEAICGGE VKKDNGHIQSPNYPDDYRPSKVCIWKITVSPGFHVGIIFQSFEIERHDNCAYDYLEIRDGPSESSKELGR YCGYDKPDDIKTTSNKVWMKFVSDGSINKAGFSVTFFKEADECSRSDNGGCEQRCVNTLGSYKCACDPGY ELAADKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLKFDFFETEGNDVCKYDF VEVRSGLTADSKLHGKFCGAEKPDVITSQYNNMRIEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQHEC LNTFGTYMCQCRSGFVLHDNKHDCKEAGCDHKVTSISGTITSPNWPDKYPTKKECTWALTTTAGHRIQLT FTELDIESHQECTYDHLEAYNGKDAKAPVLGRFCGAKKPEPIMSTSNKMFLKFFSDNSVQRKGFQASHTT VCGGQMRAEVKTKDLYSHAQFGDNNYPSGTDCEWVIMAEEGYGVELIFQTFEIEEEADCGYDYMELFDGY DGSAPRLGRYCGSGPPEVVYSAGDSVMIKFHSDDTINKKGFHLRYTSTKFQDTLHTRK >XP_019347110.1 PREDICTED: bone morphogenetic protein 1 [Alligator mississippiensis] MAGGRARCLLLAFAVLGRALDVADYPDYAEPEPEPLDYKDPCKAAAFLGDIALDEEDLRMFQADRITDLT RHTTLRVATNSSGSNTNNTRLRPRRHRKRHGWLVRQRSRSRRAATSRPERVWPDGVIPYVISGNFSGNQR AIFRQAMRHWEKFTCVTFLERTEEDSYIIFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHV IGFWHEHTRPDRDDHVAIIKENIQLGQEYNFLKMEPEEVESLGETYDFDSIMHYARNTFSRGIFLDTILP KYEVQGLRPSIGQRTRLSKGDISQARKLYRCPDCGETLQESQGNFSSPDFPNGYAAHKHCVWRISVTPGE KIILNFTTLDIYRSRLCWYDYVEVRDGFWRKATLRGRFCGNKLPEPIISTDSRLWIEFRSSSNWVGKGFF AAYEAICGGEVKKDNGHIQSPNYPDDYRPSKVCIWKITVSPGFHVGIIFQSFEIERHDNCAYDYLEIRDG PSESSKELGRYCGYDKPDDIKTTSNKVWMKFVSDGSINKAGFSVTFFKEADECSRSDNGGCEQRCVNTLG SYKCACDPGYELAADKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLKFDFFET EGNDVCKYDFVEVRSGLTADSKLHGKFCGAEKPDVITSQYNNMRIEFKSDNTVSKKGFKAHFFSDKDECS KDNGGCQHECLNTFGTYMCQCRSGFVLHDNKHDCKEAGCDHKVTSISGTITSPNWPDKYPTKKECTWALT TTAGHRIQLTFTELDIESHQECTYDHLEAYNGKDAKAPILGRFCGAKKPEPILSTSNKMFLKFFSDNSVQ RKGFQASHTTVCGGQMRAEVKTKDLYSHAQFGDNNYPSGTDCEWVIMAEEGYGVELIFQTFEIEEEADCG YDYMELFDGYDGSAPRLGRYCGSGPPEVVYSAGDSVMIKFHSDDTINKKGFHLRYTSTKFQDTLHTRK >XP_020755633.1 bone morphogenetic protein 1 [Odocoileus virginianus texanus] MGESEGPRTRESDSRRRGDAARDEGGQSGAEAARSTRRRVRRPRRGLGPDTPGTGAPSPAPPPRAPRRRS PLRAGRLRALPASGWLLRVMLLLARPGRPLDLADYTYDLGEEDDAEPLNYKDPCKAAAFLGDIALDEEDL RAFQVQQAADLRQHATRRSSIKAAVSGNSSALNSQNTSTKPQRRSHGRWRSRSRSRRAATSRPERVWPDG VIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGK NCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYA RNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYS AHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLW VEFRSSSNWVGKGFFAVYEAICGGDVKKDNGHIQSPNYPDDYRPSKVCVWRIQVSEGFHVGLTFQSFEIE RHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSR PNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVA PTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSK KGFKAHFFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSSSGTITSPNW PDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVYDGRDSKAPVLGRFCGSKKPEPVLAT GNRMFLRFYSDNSVQRKGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVE LVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRY TSTKFQDTLHSRK >XP_040202086.1 bone morphogenetic protein 1 isoform X1 [Rana temporaria] MPWTGRAPPLFLWLLLLPGVIPLGEEDYTDLYTELDESEEHIDYKDPCKAAAFIGDIALDEEDLALFKID RIVDLRNRTISTVSRPARNGTLSRTGRRARTDRRVSRGRRAATSRPERVWPHGIIPYVVSGNFTGSQKAI FRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIG FWHEHTRPDRDHHVTIIRDNIQPGQEYNFLKMEQEEVESLGETYDFDSIMHYAKNTFSRGIFLDTILPKY EVNGVKPSIGQRTRLSVGDITQARKLYQCTACGDTLQDSQGNFSSPGYPNGYSAYVHCVWRLSVTPGEKI MLNFTSLDVYRSRLCWYDYIEVRDGHWKKAPLIGRYCGEKIPEPIISSDSRLWIEFRSSSNYVGKGFHAV YEALCGGEMKKDNGHIQSPNYPDDYRPNKSCVWKLRVSEGFNIGVTFQSFEIERHDSCAYDYLEIRDGNT EFSPLIGRFCGYDKPDDLKSSSNQLWVKFVSDGSINKAGFSIHFFKEVDECSRPHKGGCEQRCVNTLGSY KCACEPGYELAPDKKSCEAACGGFLTKLNGSLTSPGWPKEYPPNKNCIWQLVAPTQFRISLKFDKFETEG NDVCKYDYVEIRSGLTADAKLLGTFCGAELPPVITSQYNNMRIEFKSDNTVSKKGFRATYYSDKDECSRD NGGCQHECTNTQGSYTCHCRSGFTLHENKHDCKEAGCNHKVLASNQNISSPNWPDSYPSKKECTWQVTST AGHRVKLIVKEVDLESHQECIYDHVEVYSGTDAQSPVLKRLCGSKVPEPIIAPGSSMFVKFVSDNSVQKK GFLAELTTECGGTLQAEVRTKDLYSHAKFGDDIHPSATECIWHIVSEGKYGVELVFQSFELEEEQDCGYD YIELYDGPTEGAPRMGRYCGSGPPEEVYSTGESLTVRFHSDDSINKKGFHIRYTSTKFQDTLNARK >XP_039272807.1 bone morphogenetic protein 1-like [Styela clava] MADFCRAKFRTEKAFFCADIDPSVCCKRGYFRSVKMASGGCMERQRTNMKFLKTKESLSNVLLHKEIPLMDEQRTLCSGC LNMRSTKTYRRRLTLFAAMAIYILPLLLLQPTGVQGLAPGVTWSVVAGISVINFQIESVNSQEQTTIWVDQPEESEDKIL KDPCKAPLFLGDIALDEVDVEDIFGETVQEFMDHVGNDDSIEARDTTEDDGDDKKSINSQKSKKHSVREASKGLRQNDPS AVDLDEQALRNKTESELSRIPTLREIVRRRKHSKKTEGVKLDSGKRRKNGRRGRKRRGRYRSRIQRTEAVHKRMRRAATA RPERIWPAGVIPYVISANFTGSQRAMFKQAMRHWEAQTCITFIERTDEEAFIKFTYRPCGCCSYVGRRGGGPQAISIGKN CDKFGIVVHELGHVIGFWHEHTRPDRDRHIEIIYKNIQPGQEYNFEKMDSSEINSLGETYDYYSIMHYARNTFSKGMFLD TIKPRVDANGARPTIGQRTRLSDGDVAQAKKLYQCNTCGYTLQDTSGNITSPNYPQYYPAESHCIWRISVTPGEKIVLDI TSLDIYESEGCYYDFLEIRDGHWYRSPKIGQYCGRSLPATITSTDSRLWLQFRTSTYYQGRGFTLKYEAVCGGTIRKESG QIQSPNYPDDYRPSKECIWKVVVDEGFRVGLSFQAFEVERHDTCSYDYLEVRDGPTADSDLIGRFCGYDKPEDVKSTSNT LWIKFVSDGSVNKAGFAASFFKEIDECEDKRKSGCQQGCVNTLGSYKCVCDPGYELAADGRTCEAACGGSVTNLDGYITS PNWPNEYPTNKKCVWQIVAPPQHKISIQFEKFELEGNEVCKYDYVEIRSGLSDDAKFHGRFCGLELPPVIRSTINEMSLA FKSDDTVSKRGFKIKFFSDKDECAISNGGCEHECVNTIGSYSCTCRNGYVLHTNKRGCKEAGCKHDIKTAVGEITSPNWP NKYPSRKECTWLIRTTPGHRVKVVFHEFELETQPECAYDHLELYDGSDSDQTVLGRYCGSKKPGTIVATTSIMFIKFFSD ASVQKRGFSATHQTVCGGNLNASTRSKDLFSHPQYGDNNYISGQECDWIITADTGLVVRLTFTAFEVEEETDCSYDFVEV YDGEDDSATRFGRYCGSKALSTIMSTSGSLLLRFHSDDTINKKGFHARYSSSSYEDISESSSTGRRI >XP_038060664.1 bone morphogenetic protein 1 homolog isoform X1 [Patiria miniata] MGPVTLNHHLHRTFVLSLCLLPCLLLTVHVQSSCAHDLKDGMKLSRHHNKMQDEGDPHVYWRSTVTEEFADPCKADGFLG DIALTEEQYQQEIGRYKQKLQEYKQSKGIRKKTNKQHEEKQLAKEEKRLAKERRKLQRKEKKAIKEEKREERRQSRRPHL ETIQIVQEEEETERGTDEVTTETHHRVARAVTSRPERKWPYGVIPYVIDGNFTGSQRAMFKQAMRHWENYTCITFVERSP TQHRNYIVFTYRSCGCCSFVGMRAEGAQAISIGKNCDKFGVVVHELGHVVGFWHEHTRPDRDDHVTIVKENILPGQEYNF NKLLPEEVDSLGQPYDFASIMHYARNTFSRGIWLDTVIPQRDPDAVPRAEIEIGQRKQLSEGDITQANLLYKCPACGRTL QETTGNFSSPGWPEQFNSRESCVWRISVTPGETIVLTFEDFELVGSDDCWYHHVEVRDGHWRFSNVLGRFCGSNIPPVIV STDSRLWIELKSSPTGNAVSRGFAAHYEAVCGGNISKESGMLQSPNYPDDYRPDKSCVWYLTMPEGFQVGLNFQSFEVER HDNCIYDYVEVRDGHEDDSPLIGKYCGYLMPEDIKSSSNKLRVKFVSDGTVNKGGFSADFFKEDDECSKNNGGCEQICVN TIGSYRCECEPGFELKADGESCEVACGGFLTSLQGNITSPSYPDLYPRDKNCVWHLVAPSLYRISLQFLSFELEGNDVCK YDYVEVRSGLTEVGDLHGKFCGDDIPDTITSRYNNMRIEFKSDSTVSRPGFFAMFFADIDECEKNNGDCQHVCVNTLGSY TCSCRNGFTLHENGHDCKESGCRHDIRSSHGEITSPNYPDNYPKRKECTWHIVATPGHKVELVFNDFDLEHHLECAYDHV VIYDGDSSEGHLLGRFCGTRIPDPVLANTNQMYITFFSDASVSRRGFFATHSTICGGVLQADYVSQKLYSHADYGDNNYG SQEDCEWTILAPQGYSVRLMFRSFDIEHETECDYDSLEVLDGDSYDSERIGRFCGHKIPDDIISQGENLRLIFRSDDTIS KKGFYAEYQIS >XP_030834881.1 bone morphogenetic protein 1 homolog isoform X1 [Strongylocentrotus purpuratus] MDLLYYMTVSLLGFILSLTTFIGETTRALSDDVSSPCKASGFLGDIALTEDDYEREMIRARHNREQYRRRILQERHTRTT GARHHIKKRTIEEAKVRHVRAVTARPERRWTDAVIPYEIDGNFTGSQRAMFKQAMRHWENYTCITFVERNPANSEHDNHI VFTYQACGCCSFVGRKGDGAQAVSVGKNCDKFGVVVHELGHVVGFWHEHTRPDRNEFVGIVHQNIVPGQEYNFRVLDAAE VDSLGETYDFASIMHYARNTFSRGIWLDTILPRKDPESGIRPEIGQRKHLSEGDIIQANLLYKCPSCGRTLLESTGNFSS PEWPGQYDGDQTCVWRISVTPGETISLQFTGFELVGSDGCWYNYLEVRDGHWRHSPLLGRFCGASLPDPILSSDSRLWIE LKSSAHRYSRGFAANYEAICGGHIERESGTLQSPNYPDDYHPSKECVWLITMPANYTVGLSFQSFEIERHETCIYDYVEV RDGHEDTSPLIGRYCGYFIPDDIKSTGNKMMVTFVSDGSVNKGGFSADFFKEKDECAQPDQGGCMDVCVNTIGSYRCDCR PGYELSSDGRRCEVACGGLFTGLRGNISSPSYPEPYPRDKNCVWQIVAPSNYRISLQFITFDLEGNEVCKYDYVDVRSGL NEEGTLHGKFCGNEIPETITSRFNNLRIDFRSDNTVAKEGFFANFFADVDECEEGNGGCQHICTNTLGSYTCSCRNGFTV HENLHGCKESGCRREIQSTTGIITSPNYPDNYPKRKECTWHISANPGHKIVLSFDDFDLEQHQECTYDRVQVFDGDSDEG QVLGRYCGATIPDAVVSSSNHMFIRFYSDASVSRSGFSATHSTQCGGRLEAELSAQRLYSHADYGDQNYENQESCEWTIV SPDDHFIHLWFRSFDIEHETECNYDQVMILDGDNHAAESFGKFCGHRAPDDIVSSGDSLMITFSSDDTINKKGFLAIFKL TDGELLEGAGEEEEEIYYN >CAE1240683.1 tok [Sepia pharaonis] MLSSGSYLLLFVFLMLCMQFHCQGTVQGLSLPEPKSLPMHRISSKDPVSLYTEQDSTNISYKQPTRKTSNDLYMDPCKAA GFINDIALTDDDVHDLMKMWHNNIEVQVDDPNVRHPRKISEPVSKRRPRKKNKGSHRKRKRCRKKDPKCNKRKSKDTTKK NSPKQKPVSEASRSWRTRRAATARQDRLWEYGVIPYQIEANFSGPHKALFRLAMRHWENHTCITFVERTPEHEDYIVFTE RPCGCCSYVGKRGNGAQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDDHVQIIYKNIMPGQEYNFNKLTPADVNSL GEEYDYGSIMHYARNTFARATFVDTILPKRKYGTRDIGQRIKLSPGDIRQANRLYRCASCGRTLQAATGEFSHKPNQQRT EEREVCEWRISATHGEKIVLNITSLDVPESRNCVTDYLEVRDGYYERSTKLGKFCGKTVPGVLQSTDSRMWLRFVSTQKK GEGFVAKYEAICGGVINKSRGTLTSPNSPDDYRANQECVWRITVPKAYLVGLMFQSFEIENHDNCVYDYLEIRDGPDETS PSLGKFCGYKVPEDIKSSGNQLYVKFVSDGSVQKAGFSATFTEEYNECLTDYHGCDHICVNTLGSYKCMCEIGYELHSDG RKCEDACGGYISIENGTFQSPSFPDLYPTNKYCVWQIVAPKQHRITLNFSYFDLEGNNQDCEYDSVRVSNGLNSDTKAIG IFCGSTLPDSITSSENSLRIEFSSDNSVQKTGFNATFFTDKDECALKNGGCQQICRNTIGSYQCACQNGFTLHENKHDCK EGGCKHQIKTPSGNINSPKWPDFYPSRKDCVWTFTVTDGHRVKLEFEEFELEPHQECTYDHIEIFDGTSTNSRSLGRFCG NKIPPPTYSSGNTMFMIFYSDASVQRKGFSAMHSTVCGGHLLAKTEPKFIYSHAKYGDQNYDNAADCDWIIEAEDDQRIY VEFKAFEIEDESECMYDYVKLYDGKSDTGSAIGKYCGSNKPPPVTSSGRILTIRFVTDDTVNWKGFSLTYRLAEDQSTGG GETQELPEVQG >XP_006567027.2 tolloid-like protein 1 isoform X2 [Apis mellifera] MVASQEKSEPIMVDRNQYSMDGELEGGFSFNARNEDARPGVRDEGVEFRLESTTPPTKKRHSARKQGREASQTASNATKS MQAFLRTSEELNVAFPTSTEGTNQMRNLNAENIEQVFTIQPESSTRNTSKQRHRRHHRRRTPKRRHRRRKIPLIRRDLDD SSDEVVSFHDRQLRSIQFYDMEHKWKHGGARKRERFSSRARRAATARKERVWDHGVIPYEIDGNFSGAHKALFKQAMRHW ENFTCVKFVERVPQEHPNYILFTERPCGCCSFVGKRGNGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVQI IRDNIMSGQEYNFNKLTEDEVNSLGLPYDYDSIMHYAKNTFSRGTYLDTILPMEVHGKKRPEIGQRLRLSEGDIAQTNLL YKCYKCGRTFQENSGSFGSPTHPNSSPPSEGERCEWRITATHGERIVLNITSLDIFKSNFCRSDYLEIRDGYWYKSNVLG RYCGSGKIHEPVVSTGSRMLVTYVTSNYQSGHRGFTASYEAVCGGEIELEDTGHLESPNYPDGYQSSKECVWKLSVPQNF QVALKFQSFEIENHDNCVYDYVEVRDGHNADSPLIGVYCGYKIPPDIKSTGNKLLVKFVSDGSVQKAGFSATFMKEFDEC VLIDHGCEHNCINTLGGFECSCKPGYELHSDGKHCEDACGGVFEDSNGTITSPSFPVTYPGNKDCVWEIIAPPQYRITLN FTHFDLEGTNARQQECEYDSVEVSSKLGDDILRKHGVFCGSRLPSLITSEGNSMRVTFTSDNSIQKTGFAAVFFTDMDEC ATNNGGCQHECRNTIGSYQCSCHNGFTLHENGHDCKEGGCKYEIAAPMGTITSPNYPDYYPGLKDCVWHFVTKPGHRIKL VFKVFEMESHQECNYDHIAIYDGDSPDSHVLGKFCGTKEPHPILATGNQMYMVFKSDASVQRKGFFATHSTACGGHLVAT NEIRHLYSHARYGVHNYDHRTDCDWAIEAPPGKNVHLTFVTFQLESESDCNYDFVEVYSGLDTSGLLYGRFCGNSNTTDF ISINEALLVRFRTDDTISNKGFMALFVAVDRQDSGENYGGSEDEDADEENL >NP_001287510.1 tolkin, isoform C [Drosophila melanogaster] MRRRRGTPLGVSWTNCVLLLATGLLVVLISVHAKNPRPHRGLPAPAPAPVPASVDQVATENAHRREPTVDGSVLQRLSGS DRAVDEDEDVDEDEDEGLKHQHLEHRQQFDAYLGTIRRLRRPYRSKYTIEQLMRLHVTPKVSGDIDMDPCKAGGFMGDIA LPEGDSGPVVAHTPIDDEEQERQEVEQLLADSPSPVHDPPSVSGAANSGPTKFNATFQLDLEKLKQEVYHEGLQVEEEGL TDIIRKKTKLPSSGPVNLKAGQSQSQSQSANEPVKPGSESPSDYAQASSYKNEVLPPSEQRIHTDKPARLTLAEIGPKFS NKTQSLHRNVDTRKIQSDNKDIEDDSGNNFVAERRPSQIVPTSLPEQRSTPAHVYSNAGGNGMQLDDEVDFLHSRGVVRR RHRRGPKQRRSNQHLEHEVKLQRLREELSRPVIEAHHHQSHHQKQAQHRQHHQSHHRKKHRRQQQHHRRRGQSTTQYVNH SPPGFNQSQQAQQQSVPEMDLLKAETSKDEEPLRHRVARAVTAKKERIWDYGVIPYEIDGNFSGIHKALFKLAMRHWENS TCIKFVERDPEIHPNYIVFTVRSCGCCSFVGKRGNGPQAISIGRNCDKFGIVVHELGHVVGFWHEHTRPDREKHVVIEHN NIMKGQDYNFNMLSPDEVDSLGMAYDYDSIMHYARNTFSKGTYLDTILPIEMKGRKRPEIGQRLRLSQGDIAQANLLYKC PKCGRTFQESSGIFASPSHYTAGALSNETEHCEWRITATYGERVELKLENMNIFKSNNCETDYLEIRDGYFEKSPLIGRF CGKVDKEVIRTESSRMLLTYVNTHRIEGFRGFKAEFDVVCGGELSVDDAVGRLESPNYPLDYLPNKECVWKITVPESYQV ALKFQSFEVENHDSCVYDYVEVRDGPGQDAPLIGVFCGYKPPPNMKSSGNSMYVKFVSDTSVQKAGFSAVFMKEVDECET QNHGCEHECINTLGGYECSCRIGFELHSDKKHCEDACGGVIEYPNGTITSPSFPEMYPLLKECIWEIVAPPKHRISLNFT HFDLEGTAHQQSDCGYDSVTVYSKLGENRLKRIGTFCGSSIPPTATSESNALRLEFHSDKSIQRSGFAAVFFTDIDECAV NNGGCQHECRNTIGSYICMCHNGYSMHENGHDCKEGECKYEISAPFGTIFSPNYPDSYPPNADCVWHFITTPGHRIKLIF NEFDVESHQECTYDNVAVYDGESESSSVLGRFCGDKIPFPISSTSNQMYMVLKTDKNKQKNGFTASHSTACGGYLRATSQ VQQFYSHARFGNQDYDDGMDCEWTIAAPDNSYVQLIFLTFDIESSENCTFDYVQVFSDIDDVYGQYGPMYGQYCGNVLPQ DINSMTHSLLVRFKTDGSVPMKGFSASYVAVPNSGEYDHSDEDVENSYSSEMVTPFPGSLKSIYIEDTQEETDEYSDFSG NQLVFNGQYRGRYSLPKRYYSGKA >XP_031559878.1 tolloid-like protein 1 [Actinia tenebrosa] MAWTAMVVTVVFLVCVVNGDNEDYDPCKADGIIQGDIATNRRQMRTRRAATADRNRFWKDGMIPYDIEIDYTGEQKATIL RAMRHWENFTCLSFIEKSDQDDDYIYFHNGRCGCCSFVGRKGNGRQGISIGKNCDKFGIVVHEIGHVVGFWHEHTRPDRQ EYVTIINENIKKGEEHNFQKLTNRDIDSRNEDYDYGSIMHYGKYTFSTSKNHVTILPKRNPFSRMVPIIGQREKLSNGDV RQTHKMYRCPECGRTLQEPKGSFTSPGYPKPYSQNKHCEWRISVTPGERIVLNFTKFNLRKASSNRGCKHDFLEIRDGHG RKSNLIGRYCGKKFPPTIWSTGSRLWIKFKSGSSEIKPEFGFAAKYETRCGGPIRKTHGTIQSPNYPSWYPSKKECVWTI ELPSKNLNVGVRFVAFDIEAHEQCDYDYLQLFNGPDTSSPSLGKFCGKTIPSDIKSNSSYLTLKFNSDTSINKPGFYITF FSERNECKVNNGGCSQICRNTLGHYECECYPGFELHSNGKDCEAACGGILSDRNGTIMSPSYPANYPKNKGCTWQITGLK GQRVSLKFKEFKLEGSANGNCRYDYVEIRDENNKVLKKLCGSSIPKTITSPSNVMFVDFRSDHTQSRKGFLAMYYSDEDE CQKRKGGCQHICVNTIGSYRCACKPGFTLHSNKHSCKEASECSATLTTQTGLIMSPNYPGVYQHKKDCTWKIVVKPGSHV ELNFRFLQIEEANDCRYDYVEIFSGTGGQAESIGRVCGNSLPSPVLSKAHKLMIKFHSDALIAKRGFKARYNAICGAKLN AINTARTFYSHPAYGDDDYSPSVKCRWTISTRNGFVKLRFKEFEVEKEKYCSYDGVTIRDGSNATSPLLGKICGNSAKNA KREFLSTSNKMFIEFVSDLTTQKKGFIAEYVRVKRKGRNRSKEYKTGKI >NP_001360030.1 Zinc metalloproteinase nas-39 [Caenorhabditis elegans] MRFSANIAIIVNIIFLFIVVEFVLPTFIRSGDVRFRRYYRNNGRVSRAATAKKERIWPEGIIPFVIASNFSGEHQHLFLR AMRHWENFTCVSFVPRQPHHKHYITFTVDKCGCCSYVGRRGEGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDM YVDIFYKSIQTGQDYNFEKSKPEEVDSLGEPYDFSSIMHYARDTFSRGAFYDTILPKPNSGFRLEIGQRVQLSEGDIRQT KKLYKCAECGGTLMQESGNLAIQHAGVCTWHIISPQGHTIFLNITGSTLSPPSSLCGKEEDNVITVRDGVSISSPVLDRI CGGDSLFRTIASSGNRMLIQVRSSTPAASLPFATYYAICGGPIYANEGVIHSPKYPESYPPNSDCQWTIHVDENSQVAIE FVYFHLEQHKECIYDRLILTEGISKNSKKDGKEMSETFCGLIEKKTIVSKTNQISLRFFSDNSVQKTGFELRFTKELNEC ATDKNICHHYCVNTVGGFKCACRVGYSLSSNGFSCDSTCGGYLKASNGSISSPNFPEMYPNSKTCIWEIEAPDGYHIFLN FTKFNVEGMKTECAYDYVKIGDSEKLCGEYHEALLFTTPRNRVRIEFSSDSSVERDGFFANFIADFDECQNDNAGCEHTC QNRLGSYVCTCNPGYILAEDKHNCKEGSCFFEVNAPAGDINSPNYPNDYPKGQNCSWHFVTTPGHRLMLTFSSFQVEEHA QCKYDAVSVYDGGDGSAQLAGVFCGLAPPPLLLSSSNELYLTFSSDASVSRRGFQAHYTSLCGGRLTAESTPGHIYSHAT FSDSKYGKNQDCSWIVRAKSPGRGVRIQFSTFNIESEEGCQYDYIEIYDGPEATLERLVGRFCGDTSPEVITSTGPELLL IMHTDNAEEEKGFVAEYREAPRSSSTKRTFVSKTRHSPLEEPIHDRNE >XP_043308815.1 bone morphogenetic protein 1 isoform X1 [Cervus canadensis] MPGVARPPLPLLLWLLLLARPGRPLDLADYTYDLGEEDDAEPLNYKDPCKAAAFLGDIALDEEDLRAFQVQQAADLRQRA TRRSSIKAAVSGNSSTLNSQNTSTKPQSRSHGRWRSRSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHW EKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVR ENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYK CPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCG GKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKKDNGHIQSPNYPDDYRPSKVCVWRIQVSEGFHVGLTFQ SFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGG CEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFET EGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDC VNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSSSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQP ECAYDHLEVYDGRDSKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGFQASHSTECGGQVRAEVKTKDLYSHAQ FGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKF HSDDTITKKGFHLRYTSTKFQDTLHSRK >KAF4019395.1 hypothetical protein G4228_011326 [Cervus hanglu yarkandensis] MDVGSKEVLMESPPDYSAVPGGRLRIPCCPVNIKRLLIVVVVVVLVVVVVVGALLMGLHMSQKHTEMLLIAYKPAPGTCC YIMKMAPQSIPSLEALTRKLQNLQVGVWGLRKPQRDSEDPGAKGSCADWQEADPVDSTGTGPGEMGAVGRAAFLGDIALD EEDLRAFQVQQAADLRQRATRRSSIKAAVSGNSSTLNSQNTSTKPQSRSHGRWRSRSRSRRAATSRPERVWPDGVIPFVI GGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVI GFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPI GQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDY VEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKKDNGHIQSPNYPDDYRPSK VCVWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAG FAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIW QLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAH FFSDKDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSSSGTITSPNWPDKYPSKKECTWAISS TPGHRVKLTFMEMDIESQPECAYDHLEVYDGRDSKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGFQASHSTE CGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYC GSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDTLHSRK >KAB0373058.1 hypothetical protein FD755_014717 [Muntiacus reevesi] MPGVARPPLPLLLWLLLLARPGRPLDLADYTYDLGEEDDAEPLNYKDPCKAAAFLGDIALDEEDLRVFQVQQAADLRQRA TRRSSIKAAVSGNSSTLNSQNTSTKPQRRSHGRWRSRSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHW EKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVR ENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYK CPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCG GKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKKDNGHIQSPNYPDDYRPSKVCVWRIQVSEGFHVGLTFQ SFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEGMLVRGRGRKC HRSPGRRQDSPRLRGGDTAFLVPPAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVC KYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVNTFGS YECQCRSGFVLHDNKHDCKEAGCDHKVTSSSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDH LEVYDGRDSKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNY PGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTI TKKGFHLRYTSTKFQDTLHSRK >XP_004072530.1 bone morphogenetic protein 1 [Oryzias latipes] MDLSVRCLFLLSCLGVILAIDLDAADPGYYVEPTATSEAIDYKDPCKAVAFLGDIALDEEDMRLFKVDRIIDLAQRTVQN VNHTDEGSDHSGNANNQGSQRRKRAATSRPERVWPEGVIPYVISGNFSGSQRAVFRQAMRHWEKHTCVTFIERTQEESYI VFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDEHVSIIKDNIQPGQEYNFLKMEPGE VDSLGEVYDFDSIMHYARNTFSRGIFLDTILPRYDVNGVRPPIGQRTRLSKGDIAQARKLYKCSKCGESLQDSSGNFSSP GFPNGYSAYMHCIWRISVTPGEKIILNFTSMDLYRSHLCWYDHVEIRDGYWRKAPLKGRFCGDKLPEPIISTDSRLWIEF RSSSNWVGKGFSAVYEAICGGDVKRDNGQIQSPNYPDDYRPNKACIWKISVSEGYHVGLTFQSFEIERHDSCAYDYLEVR DGISENSPLLGRFCGYDKPDDIKTSSNHLWMKFVSDGSVNKAGFAANFFKEMDECSKPDNGRCEQRCVNTLGSYKCACDP GYELAADKRSCEAACGGFITKLNGSITSPGWPREYPPNKNCIWQLVAPTQYRITLLFDVFETEGNDVCKYDFVEVRSGLS ADSKPHGKFCGSEKPEAITSQYNNMRIEFKSDNTVSKKGFKAQFFSDKDECSKENGGCQHDCVNTFGSYRCQCRSGFVLH ENKHDCKEAGCDHTVNSVSGAITSPNWPDKYPSKKACTWALSTTPGHRIKIAFNEIDMEAHLDCAYDHIQIYDGRDAKAP SLGRFCGSKKPQPIISSGNKLFIRFFSDNSVQKKGFDASHSAECGGILKAEVKTKDLFSHAQFGDNNYPGASDCEWVISA EKGYGVELIFQTFEIEEEADCGYDYMELFDGADTKSPRLGRYCGSGPPEEIYSAGDSIVIKFHSDDTINKKGFHVRYTST KFQDTLHSRK >XP_030273707.1 bone morphogenetic protein 1 [Sparus aurata] MDLTARCLFLLYCLGVILAIDLEAIDPGYYVESTATSEAIDYKDPCKAVAFLGDIALDEEDMRSFKVDRVIDLAQRTVYT VNHTDSGSTNQSSQNRQGSHRRKRAATSRPERVWPEGVIPYVISGNFSGSQRAIFRQAMRHWEKHTCVTFIERTQEESYI VFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDEHVSIIRDNIQPGQEYNFLKMEPGE VDSLGEVYDFDSIMHYARNTFSRGIFLDTILPRYDVNGVRPPIGQRTRLSKGDIAQARKLYKCSRCGDSLQDSSGNFSSP GFPNGYSAYMHCIWRISVTPGEKIILNFTSMDLYRSHLCWYDHVEIRDGYWRKAPLKGRFCGDKLPEPIISTDSRLWIEF RSSSNWVGKGFSAVYEAICGGEVKKDNGQIQSPNYPDDYRPNKVCVWKITVAQGYHVGLTFQSFEIERHDSCAYDYLEVR DGNSENSPLLGRFCGYDKPDDIKTSSNQLWMKFVSDGSVNKAGFAANFFKEMDECSKPDNGRCEQRCVNTLGSYKCACDP GYELAADKRSCEAACGGFITKLNGSITSPGWPREYPPNKNCIWQLVAPTQYRITLLFDVFETEGNDVCKYDYVEVRSGLS ADSRLHGKFCGAEKPEAITSQYNNMRIEFKSDNTVSKKGFKAQFFSDKDECSKENGGCQHECVNTFGSYSCQCRSGFVLH ENKHDCKEAGCDHTVNSVSGTITSPNWPDKYPSKKACTWALTTTPGHRIKIAFNEIDMEAHLECAYDHIEIYDGRDGKAP SMGRFCGTKKPPPITSSGNKLFVRFFSDNSVQKKGFEASHTAECGGRLKAEVKTKDLFSHAQFGDNNYPGASDCQWVISA EKGYGVELIFQTFEIEEEADCGYDYMELFDGADTKSPRLGRYCGSGPPEEIYSAGDSIVIKFRSDDTINKKGFHVRYTST KFQDTLHSRK >XP_015827829.1 PREDICTED: bone morphogenetic protein 1 [Nothobranchius furzeri] MDLSVSCWLLLSCIGAILAIDLEAIDPGFYVEPSATSEAIDYKDPCKAAAFLGDIALDEEDLKNFKVDRIIDLAQRTVQT FNHTDAGSDNRSQNRQSPQRRKRAATSRLERVWPEGVIPYVISGNFSGSQRAIFRQAMRHWEKHTCVTFIERTQEESYIV FTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDEHVSIIRDNIQQGQEYNFLKMEPGEV DSLGEVYDFDSIMHYARNTFSRGIFLDTILPRYDVNGVRPPIGQRTRLSKGDIAQARKLYKCSKCGDSLQESSGNFSSPG FPNGYSAYMHCIWRISVTPGEKIILNFTSMDLYRSHLCWYDHVEIRDGYWRKAPLKGRFCGDKLPEPIISTDSRLWIEFR SSSNWVGKGFSAVYEAICGGEVKRDNGQIQSPNYPDDYRPNKVCVWKISVSQGFHVGLTFQSFEIERHDSCAYDYLEVRD GLSENSPLLGRFCGYDKPDDIKTSSNHLWMKFVSDGSVNKAGFAANFFKETDECSKPDNGRCEQRCVNTLGSYKCACDPG YELAADKRSCEAACGGFITKLNDSITSPGWPREYPPNKNCIWQLVAPTQYRITLLFDVFETEGNDVCKYDYVEVRSGLSA DSRLHGKFCGAEKPEAITSQYNNMRIEFKSDNTVSKKGFKAQFFSDKDECSKENGGCQHECVNTFGSYSCQCRSGFVLHE NKHDCKEAGCDHTVNSVNGVITSPNWPDKYPSKKACTWALTTTPGHRIKIAFNEIDMEPHLECAYDHIEVYDGRDGKSPS LGRFCGSKKPPPIESSSNKLFIRFFSDNSVQKKGFEASHSAECGGRLKAEVKTKDLFSHAQFGDNNYPGASDCQWVISAE KGYGVELIFQTFEIEEEADCGYDYMELFDGADTKSPRLGRYCGSGPPEEIYSAGDSIVIKFHSDDTINKKGFHVRYTSTK FQDTLHSRK >XP_018106279.1 bone morphogenetic protein 1 L homeolog isoform X1 [Xenopus laevis] MPWLGSPPLLLWALLAGMLHLGQGQEFLDYSYDLEEVVEESIDYKDPCKAAAFWGDIALDEEDLANFKVARIVDLTKHTI STVSGAASNSSRPQRGRRTRKERRRSRERRAATSRPERVWPDGVIPYVISGNFSGSQRAIFRQAMRHWEKHTCVTFLERT DEDSYIIFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDDHVSIIRENIQPGQEYNFL KMEPEEVESIGETYDFDSIMHYARNTFSRGIFLDTILPKYDVNGVRPPIGQRTRLSSGDIAQAKKLYRCPACGETLQDSQ GNFSSPGFPNGYSAYMHCVWRLSVTPGEKIILNFTSLDLYRSRLCWYDYIEVRDGFWKKAPLRGRFCGDKIPEPIISTES RLWIEFRSSSNWVGKGFQAVYEALCGGDVKKDSGHIQSPNYPDDYRPNKACVWKLSVSEGFHVGISFQSFEIERHDSCAY DYLEIRDGSSESSPLIGRFCGYDKPDDIKSSTNQLWVKFVSDGSINKAGFSLNYFKEVDECSRPNNGGCEQRCVNTLGSY KCACDPGYELGPDKKSCEAACGGFLTKLNGSITSPGWPKEYPPNKNCVWQLVAPTQYRISLKFDQFETEGNDVCKYDFVE VRSGLTSDSKLHGKFCGTELPAVITSQYNNMRIEFKSDNTVSKKGFQANFFSDKDECSQDNGGCQHECTNTLGSYICQCR SGFTLHENKHDCKEAGCDHKVTGSTGTISSPNWPDKYPSKKICTWQITATPGHRAKLTVSEVDLESHQECLYDHVEVYSG CDAQSPALNRFCGSKIPDPIISPGNTMFLKFMSDNSVQKRGFLGELSSVCGGTLHAEVRTQDLYSHAKFGDDTHPSGTEC LWHIVSEAGYGVELVFQSFELEEEPDCGYDYMELYDGPDEGAPRLGRYCGSGPPEEVYSAGDALTIKFHADDTINKKGFH VRYTSTKFQDTLHARK >XP_040530575.1 tolloid-like protein 2 isoform X1 [Gallus gallus] MGRGATPLRRLLLSLLLLPGPGLAAGEPETAEEQMEYRDPCKAAAFWGDIALDEDDLKLFQIDRTVDLTKHSAGNARHTS GGLGEQSFEPSENTTSTDSKKAVKTDGRQNTTLVRSLKKKEYKDESGMDARSSPRVRRATTSRAERIWPGGVIPYVIGGN FTGTQRAIFKQAMRHWEKHTCVTFVERTDEESFIVFTYRTCGCCSYVGRRGGGPQAISIGKNCDKFGIVAHELGHVVGFW HEHTRPDRDQHVTIIRENIQQGQEYNFLKMEAGEVNSLGETYDFDSIMHYARNTFSRGVFLDTILPRRDDNGVRPTIGQR VRLSQGDIAQARKLYKCPACGETLQDSTGNFSAPGFPSGYPSYSHCVWRISVTPGEKIMLNFTSMDLFKSRLCWYDYVEV RDGYWRKAPLLGRFCGDKIPEPVISTDSRLWIEFRSSSNILGKGFFVVYEAICGGEVRKDAGQIQSPNYPDDYRPSKECI WKITVSEGFHIGISFQAFEIEWHDACSYDYLEIRDGLTENSPLIGQFCGYEKPEDIKSSSNKIWMKFTSDATISKAGFAA NFFKEMDECSQPDNGGCEQHCENTLGSYKCTCEPGYELTADKKSCEAACGGFITKLNGTITSPGWPKEYPTNKNCVWQVV APAQYRISLQFEVFDLEGNDVCKYDYVEVRSGLATDSKLHGKFCGSEKPEVITSYSNNIRLEFKSDNTVSKKGFKVHFFS DKDECSKDNGGCQHECINTFGSYVCQCRNGFKLHENNHDCKEAGCEHKLSSAEGMMSSPNWPDKYPSRKECTWNISATPG HRVKVTFHEFEIEQHQECAYDHLEMYDGPNSKSPILGRFCGSKKPDPVVASTNKMFLRFYSDASVQRKGFQAKHSTVCGG LLKAEVQTKELYSHAQFGDNNYPGQANCDWVIVAEDGYGVELMFQTFEIEEEADCGYDYMEIYDGYDSTAPRLGRFCGSG PLEEIYSAGDSIMIRFHTDDTINKKGFHAQYISTKFQDALHMRK >XP_031410433.1 tolloid-like protein 2 [Meleagris gallopavo] MAKHPEGEVFCFSPAAFWGDIALDEDDLKLFQIDRTVDLTKHSAGNARHTSGGLGEQSFEPSENTTSTDSKRAVKTDGKQ NTTLVRSLKKKERKDESGMDARSSPRVRRATTSRAERIWPGGVIPYVIGGNFTGTQRAIFKQAMRHWEKHTCVTFVERTD EESFIVFTYRTCGCCSYVGRRGGGPQAISIGKNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQQGQEYNFLK MEAGEVNSLGETYDFDSIMHYARNTFSRGVFLDTILPRRDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDSTG NFSAPGFPSGYPSYSHCVWRISVTPGEKIMLNFTSMDLFKSRLCWYDYVEVRDGYWRKAPLLGRFCGDKIPEPVISTDSR LWIEFRSSSNILGKGFFVVYEAICGGEIRKDAGQIQSPNYPDDYRPSKECIWKITVSEGYHIGISFQAFEIEWHDACSYD YLEIRDGLTENSPLIGQFCGYEKPEDIKSSSNKIWMKFASDATISKAGFAANFFKEMDECSQPDNGGCEQHCENTLGSYK CTCEPGYELTADKKSCEAACGGFITKLNGTITSPGWPKEYPTNKNCIWQVVAPAQYRISLQFEVFDLEGNDVCKYDFVEV RSGLATDSKLHGKFCGSEKPEVITSYGNNMRLEFKSDNTVSKKGFKIHFFSDKDECSKDNGGCQHECINTFGSYVCQCRN GFKLHENNHDCKEAGCEHKLSSAEGMMSSPNWPDKYPSRKECTWNISATSGHRVKVTFNEFEIEQHQECAYDHLEMYDGP NSKSPILGRFCGSKKPDPVVASTNKMFLRFYSDASVQRKGFQAKHSTVCGGLLKAEVQTKELYSHAQFGDNNYPGQANCD WVIVAEDGYGVELIFQTFEIEEEADCGYDYMEIYDGYDSTAPRLGRFCGSGPLEEIYSAGDSIMIRFHTDDTINKKGFHA RYISTKFQDALHMRK
Mafft alignment of selected proteins >sp|P13497|BMP1_HUMAN Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 PE=1 SV=2 ------------------------------------------------------------ --------------------------------------MPGVAR---------------- ----LP----LL----------------------LGL-------------LLLP------ --------------RPGR-------------------PLDLA------------------ ------------DYTYDLAEE-------------------------DDSEPLNYKDP--- ----------------------C-------KA-------AAFL-GDIALDEED------- ------------LRAF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QVQQAVD-----------------------LRRHTARKSSIKAA------ --------VPG-NTSTPSC--------------------------QSTNGQPQR------ ------------------------GACGRW--RGR--------SRSRRAATSRPERVWPD GVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYN FLKM-EPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVN---GVKPPIGQRTR LSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGY---SAHMHCVWRISVTPGEKII LNFTSLDLYRS---RLC---WYDYVEVRDGFWRKAPLRGRFCG-SKLPEP-----IVSTD SRLWVEFRSS--SNWVG--KGFFAVYEAICGGDVK-KDY--GHIQSPNYPDDYRPSKVCI WRIQVS-EGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGR-----YCGYEKPD DIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDP GYELAPDKRRC--------EAACGGFLTKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RISLQFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGSEKPEVI-TSQYNNM RVEFKSDNTVSKKGFKAHFFS--DK--DECSKDNG----GCQQDCVNTFGSYECQCRSGF VLHDNKH---DCKEAG-CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTF MEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQR KGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEE-GYGVELVFQT FEVEEETDCGYDYMELFDGYD----STAPRL-GRYCGSGPPE---EVYSAGDSVLVKFHS DDTITKKGFHLRYTSTKFQDT------LHSRK---------------------------- ----------------------------------- >sp|P13497-2|BMP1_HUMAN Isoform BMP1-1 of Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 ------------------------------------------------------------ --------------------------------------MPGVAR---------------- ----LP----LL----------------------LGL-------------LLLP------ --------------RPGR-------------------PLDLA------------------ ------------DYTYDLAEE-------------------------DDSEPLNYKDP--- ----------------------C-------KA-------AAFL-GDIALDEED------- ------------LRAF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QVQQAVD-----------------------LRRHTARKSSIKAA------ --------VPG-NTSTPSC--------------------------QSTNGQPQR------ ------------------------GACGRW--RGR--------SRSRRAATSRPERVWPD GVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYN FLKM-EPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVN---GVKPPIGQRTR LSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGY---SAHMHCVWRISVTPGEKII LNFTSLDLYRS---RLC---WYDYVEVRDGFWRKAPLRGRFCG-SKLPEP-----IVSTD SRLWVEFRSS--SNWVG--KGFFAVYEAICGGDVK-KDY--GHIQSPNYPDDYRPSKVCI WRIQVS-EGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGR-----YCGYEKPD DIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDP GYELAPDKRRC--------EAACGGFLTKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RISLQFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGSEKPEVI-TSQYNNM RVEFKSDNTVSKKGFKAHFFS--EK--RPALQPPR----GRPHQ---------------- ------------------------------------------------------------ -------------------------------------------------LKF----RVQK R----------------------------------------------------------- -------------------------NRTPQ------------------------------ ------------------------------------------------------------ ----------------------------------- >sp|P13497-3|BMP1_HUMAN Isoform BMP1-4 of Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 ------------------------------------------------------------ --------------------------------------MPGVAR---------------- ----LP----LL----------------------LGL-------------LLLP------ --------------RPGR-------------------PLDLA------------------ ------------DYTYDLAEE-------------------------DDSEPLNYKDP--- ----------------------C-------KA-------AAFL-GDIALDEED------- ------------LRAF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QVQQAVD-----------------------LRRHTARKSSIKAA------ --------VPG-NTSTPSC--------------------------QSTNGQPQR------ ------------------------GACGRW--RGR--------SRSRRAATSRPERVWPD GVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGVLHS SLLLLSCGSRNGASFPCSLESSTHQA--LCWTGLFL---------------RPS------ ------------------------------------------------------------ -----------------------------------------------PFP---------- -RL--------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------P----------------LAAPR-- --------------------------TLRAGV---------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------- >sp|P13497-4|BMP1_HUMAN Isoform BMP1-5 of Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 ------------------------------------------------------------ --------------------------------------MPGVAR---------------- ----LP----LL----------------------LGL-------------LLLP------ --------------RPGR-------------------PLDLA------------------ ------------DYTYDLAEE-------------------------DDSEPLNYKDP--- ----------------------C-------KA-------AAFL-GDIALDEED------- ------------LRAF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QVQQAVD-----------------------LRRHTARKSSIKAA------ --------VPG-NTSTPSC--------------------------QSTNGQPQR------ ------------------------GACGRW--RGR--------SRSRRAATSRPERVWPD GVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYN FLKM-EPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVN---GVKPPIGQRTR LSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGY---SAHMHCVWRISVTPGEKII LNFTSLDLYRS---RLC---WYDYVEVRDGFWRKAPLRGRFCG-SKLPEP-----IVSTD SRLWVEFRSS--SNWVG--KGFFAVYEAICGGDVK-KDY--GHIQSPNYPDDYRPSKVCI WRIQVS-EGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGR-----YCGYEKPD DIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDP GYELAPDKRRC--------EGC-------YDLQVGKPLLW------DRHC---------F RLS-----------------------------------THG-------PEML-------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -----------GTALRG------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ----------------------------------- >sp|P13497-5|BMP1_HUMAN Isoform BMP1-6 of Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 ------------------------------------------------------------ --------------------------------------MPGVAR---------------- ----LP----LL----------------------LGL-------------LLLP------ --------------RPGR-------------------PLDLA------------------ ------------DYTYDLAEE-------------------------DDSEPLNYKDP--- ----------------------C-------KA-------AAFL-GDIALDEED------- ------------LRAF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QVQQAVD-----------------------LRRHTARKSSIKAA------ --------VPG-NTSTPSC--------------------------QSTNGQPQR------ ------------------------GACGRW--RGR--------SRSRRAATSRPERVWPD GVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYN FLKM-EPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVN---GVKPPIGQRTR LSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGY---SAHMHCVWRISVTPGEKII LNFTSLDLYRS---RLC---WYDYVEVRDGFWRKAPLRGRFCG-SKLPEP-----IVSTD SRLWVEFRSS--SNWVG--KGFFAVYEAICGGDVK-KDY--GHIQSPNYPDDYRPSKVCI WRIQVS-EGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGR-----YCGYEKPD DIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDP GYELAPDKRRC--------EAACGGFLTKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RISLQFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGSEKPEVI-TSQYNNM RVEFKSDNTVSKKGFKAHFFSGGEL----------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -----------------------------FGLLGHP------------------------ ----------------------------PRR--------P-------------------- ------------------------------------------------------------ ----------------------------------- >sp|P13497-6|BMP1_HUMAN Isoform BMP1-7 of Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 ------------------------------------------------------------ --------------------------------------MPGVAR---------------- ----LP----LL----------------------LGL-------------LLLP------ --------------RPGR-------------------PLDLA------------------ ------------DYTYDLAEE-------------------------DDSEPLNYKDP--- ----------------------C-------KA-------AAFL-GDIALDEED------- ------------LRAF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QVQQAVD-----------------------LRRHTARKSSIKAA------ --------VPG-NTSTPSC--------------------------QSTNGQPQR------ ------------------------GACGRW--RGR--------SRSRRAATSRPERVWPD GVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYN FLKM-EPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVN---GVKPPIGQRTR LSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGY---SAHMHCVWRISVTPGEKII LNFTSLDLYRS---RLC---WYDYVEVRDGFWRKAPLRGRFCG-SKLPEP-----IVSTD SRLWVEFRSS--SNWVG--KGFFAVYEAICGGDVK-KDY--GHIQSPNYPDDYRPSKVCI WRIQVS-EGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGR-----YCGYEKPD DIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDP GYELAPDKRRC--------EAACGGFLTKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RISLQFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGSEKPEVI-TSQYNNM RVEFKSDNTVSKKGFKAHFFSVLEGAGDRHSHLSGLELLLCPHALVDTVPAPPSALHGDT HAHTHTHVHTHCPIAQ-ETCRGPPLGASRLSPQGPG--------------------HLTL APQE----------------------------------------GS--YLDFWD------ -----TH--------RGDPK---------------------------------------- ----------------------------PRR-RRKS------------------LKTF-- --SLTPATFRGIWAL--------------------------------------------- ----------------------------------- >tr|F1REM3|F1REM3_DANRE Metalloendopeptidase OS=Danio rerio OX=7955 GN=bmp1a PE=4 SV=2 ------------------------------------------------------------ --------------------------------------MELAAR---------------- ----CA----LL----------------------LSSF-----------SLLA------- ----------------AL-------------------DLDAI------------------ ------------EPGYYVETS-------------------------SPSDLIDYKDP--- ----------------------C-------KA-------VAYL-GDIALDEED------- ------------MRMF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------TVDRIVN-----------------------LADRTVTILNHTNT------ ----------G-SLSNETS--------------------------VNTTASS-------- --------------------------------RGS--------HRRRRAATSRPERVWPE GVIPYVISGNFSGSQRAIFRQAMRHWEKHTCVTFIERTT----EESYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDEHVSIIRDNIQPGQEYN FLKM-EPGEVDSLGEVYDFDSIMHYARNTFSRGIFLDTILPRYDVN---GVRPPIGQRTR LSKGDIAQARKLYKCPRCGDSLQESSGNFSSPGYPNGY---SAYMHCIWRISVTPGEKII LNFTSMDLYRS---HLC---WYDHVEIRDGYWRKAPLKGRFCG-DKLPDP-----IISTD SRLWIEFRSS--SNWVG--KGFSAVYEAICGGEVK-KDN--GQIQSPNYPDDYRPNKVCV WKITVA-QGYHVGLTFQSFEIERHDNCAYDYLEVRDGNSESSPLLGR-----FCGYDKPD DIKSSSNQLWMKFVSDGSVNKAGFAANFFKEMDECSRPDNGRCEQRCVNTLGSYKCACDP GYELAADKRSC--------EAACGGFITKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RITLLFDVFETEGNDV----CKYDFVEVRSGLSADS-RLHGKFCGAEKPEAI-TSQYNNM RIEFKSDNTVSKKGFKAQFFS--DK--DECSKENG----GCQHECVNTFGSYSCQCRSGF VLHENKH---DCKEAG-CDHVVNSVSGTITSPNWPDKYPSKKACTWALSTTPGHRIKIAF NEIDMEPHLECAYDHIEIYDGRDSKAQSLGRYCGTKKPQPIISTGNKMFIRFFSDNSVQK KGFEASHTAECGGRLKAEVKTKDLYSHAQFGDNNYPGASDCQWVITAEK-GYGVELIFQT FEIEEEADCGYDYMELFDGAD----TKSPRL-GRYCGSGPPE---EIYSAGDSIVIKFHS DDTINKKGFHVRYTSTKFQDT------LHSRKK--------------------------- ----------------------------------- >NP_033885.2 bone morphogenetic protein 1 precursor [Mus musculus] ------------------------------------------------------------ --------------------------------------MPGVARPPLP-----------L LS--LP----LL----------------------LLL-------------LLLP------ --------------RAGR-------------------PLDLA------------------ ------------DYTYDLGEE-------------------------DAPELLNYKDP--- ----------------------C-------KA-------AAFL-GDIALDEED------- ------------LRAF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QVQQAAV-----------------------LRQQTARRPSIKAA------ ----------G-NSSALGG--------------------------QGTSGQPQR------ ------------------------ESRGRW--RGR--------PRSRRAATSRPERVWPD GVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYN FLKM-EVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVN---GVKPSIGQRTR LSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGY---SAHMHCVWRISVTPGEKII LNFTSMDLYRS---RLC---WYDYVEVRDGFWRKAPLRGRFCG-GKLPEP-----IVSTD SRLWVEFRSS--SNWVG--KGFFAVYEAICGGDVK-KDN--GHIQSPNYPDDYRPSKVCI WRIQVS-EGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSNLIGR-----YCGYEKPD DIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDP GYELAPDKRRC--------EAACGGFLTKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RISLQFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGSEKPEVI-TSQYNNM RVEFKSDNTVSKKGFKAHFFS--DK--DECSKDNG----GCQQDCVNTFGSYECQCRSGF VLHDNKH---DCKEAG-CEHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTF VEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQR KGFQASHSTECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEE-GYGVELVFQT FEVEEETDCGYDYIELFDGYD----STAPRL-GRYCGSGPPE---EVYSAGDSVLVKFHS DDTISKKGFHLRYTSTKFQDT------LHSRK---------------------------- ----------------------------------- >NP_112613.1 bone morphogenetic protein 1 precursor [Rattus norvegicus] ------------------------------------------------------------ --------------------------------------MPGVARPPLP-----------L LS--LP-----L----------------------LLL-------------LLLP------ --------------RAGR-------------------PLDLA------------------ ------------DYTYDLGEE-------------------------DAPELLNYKDP--- ----------------------C-------KA-------AAFL-GDIALDEED------- ------------LRAF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------RVQQAAV-----------------------LRQQTAQRSSIKAA------ ----------G-NSSALGR--------------------------QSTSGQPQR------ ------------------------GSRGRW--RSR--------PRSRRAATSRPERVWPD GVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYN FLKM-EVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVN---GVKPSIGQRTR LSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGY---SAHMHCVWRISVTPGEKII LNFTSMDLYRS---RLC---WYDYVEVRDGFWRKAPLRGRFCG-GKLPEP-----IVSTD SRLWVEFRSS--SNWVG--KGFFAVYEAICGGDVK-KDN--GHIQSPNYPDDYRPSKVCI WRIQVS-EGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSNLIGR-----YCGYEKPD DIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDP GYELAPDKRRC--------EAACGGFLTKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RISLQFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGSEKPEVI-TSQYNNM RVEFKSDNTVSKKGFKAHFFS--DK--DECSKDNG----GCQQDCVNTFGSYECQCRSGF VLHDNKH---DCKEAG-CEHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTF VEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQR KGFQASHSTECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEE-GYGVELVFQT FEVEEETDCGYDYMELFDGYD----STAPRL-GRYCGSGPPE---EVYSAGDSVLVKFHS DDTISKKGFHLRYTSTKFQDT------LHSRK---------------------------- ----------------------------------- >XP_016814692.1 bone morphogenetic protein 1 isoform X1 [Pan troglodytes] ------------------------------------------------------------ --------------------------------------MPGVAR---------------- ----LP----LL----------------------LGL-------------LLLP------ --------------RPGR-------------------PLDLA------------------ ------------DYTYDLAEE-------------------------DDSEPLNYKDP--- ----------------------C-------KA-------AAFL-GDIALDEED------- ------------LRAF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QVQQAAD-----------------------LRQHTARKSSIKAA------ --------VAG-NTSTPSC--------------------------QSTNGQPQR------ ------------------------GACGRW--RGR--------SRSRRAATSRPERVWPD GVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYN FLKM-EPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVN---GVKPPIGQRTR LSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGY---SAHMHCVWRISVTPGEKII LNFTSLDLYRS---RLC---WYDYVEVRDGFWRKAPLRGRFCG-SKLPEP-----IVSTD SRLWVEFRSS--SNWVG--KGFFAVYEAICGGDVK-KDY--GHIQSPNYPDDYRPSKVCI WRIQVS-EGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGR-----YCGYEKPD DIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDP GYELAPDKRRC--------EAACGGFLTKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RISLQFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGSEKPEVI-TSQYNNM RVEFKSDNTVSKKGFKAHFFS--DK--DECSKDNG----GCQQDCVNTFGSYECQCRSGF VLHDNKH---DCKEAG-CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTF MEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQR KGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEE-GYGVELVFQT FEVEEETDCGYDYMELFDGYD----STAPRL-GRYCGSGPPE---EVYSAGDSVLVKFHS DDTITKKGFHLRYTSTKFQDT------LHSRK---------------------------- ----------------------------------- >XP_024852018.1 bone morphogenetic protein 1 isoform X1 [Bos taurus] ------------------------------------------------------------ --------------------------------------MPGVARPP-------------- ----LP----LL----------------------LWL-------------LLLA------ --------------RPGR-------------------PLDLA------------------ ------------DYTYDLGEE-------------------------DDAEPLNYKDP--- ----------------------C-------KA-------AAFL-GDIALDEED------- ------------LRAF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QVQQAAD-----------------------LRQRATRRSSIKAA------ --------VSG-NSSTLNS--------------------------QNTSMKPQR------ ------------------------RSRGRW--KSR--------SRSRRAATSRPERVWPD GVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYN FLKM-EVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVN---GVKPPIGQRTR LSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGY---SAHMHCVWRISVTPGEKII LNFTSMDLYRS---RLC---WYDYVEVRDGFWRKAPLRGRFCG-GKLPEP-----IVSTD SRLWVEFRSS--SNWVG--KGFFAVYEAICGGDVK-KDN--GHIQSPNYPDDYRPSKVCV WRIQVS-EGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGR-----YCGYEKPD DIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDP GYELAPDKRRC--------EAACGGFLTKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RISLQFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGSEKPEVI-TSQYNNM RVEFKSDNTVSKKGFKAHFFS--DK--DECSKDNG----GCQQDCVNTFGSYECQCRSGF VLHDNKH---DCKEAG-CDHKVTSSSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTF MEMDIESQPECAYDHLEVYDGRDSKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQR KGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEE-GYGVELVFQT FEVEEETDCGYDYMELFDGYD----STAPRL-GRYCGSGPPE---EVYSAGDSVLVKFHS DDTITKKGFHLRYTSTKFQDT------LHSRK---------------------------- ----------------------------------- >XP_020927995.1 LOW QUALITY PROTEIN: bone morphogenetic protein 1 [Sus scrofa] ------------------------------------------------------------ --------------------------------------MPGVARPP-------------- ----LP----LL----------------------LWL-------------LLLA------ --------------RPGR-------------------PLDLA------------------ ------------DYTYDLGEE-------------------------DDAEPLNYKDP--- ----------------------C-------KA-------AAFL-GDIALDEED------- ------------LRXF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QVQQAAD-----------------------LRQRTTRKSSIKAA------ ----------G-NSSTLQC--------------------------QSTRGQPQR------ ------------------------RSHGKW--RSR--------SRSRRAATSRPERVWPD GVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYN FLKM-EVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVN---GVKPPIGQRTR LSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGY---SAHMHCVWRISVTPGEKII LNFTSMDLYRS---RLC---WYDYVEVRDGFWRKAPLRGRFCG-GKLPEP-----IVSTD SRLWVEFRSS--SNWVG--KGFFAVYEAICGGDVK-KDN--GHIQSPNYPDDYRPSKVCI WRIQVS-EGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGR-----YCGYEKPD DIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDP GYELAPDKRRC--------EAACGGFLTKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RISLQFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGSEKPEVI-TSQYNNM RVEFKSDNTVSKKGFKAHFFS--DK--DECSKDNG----GCQQDCVNTFGSYECQCRSGF VLHDNKH---DCKEAG-CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTF LEMDIESQPECAYDHLEVYDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQR KGFQAAHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEE-GYGVELVFQT FEVEEETDCGYDYMELFDGYD----STAPRL-GRYCGSGPPE---EVYSAGDSVLVKFHS DDTITKKGFHLRYTSTKFQDT------LHSRK---------------------------- ----------------------------------- >XP_002818918.1 bone morphogenetic protein 1 isoform X1 [Pongo abelii] ------------------------------------------------------------ --------------------------------------MPGVAR---------------- ----LL----LL----------------------LGL-------------LLLP------ --------------RPGR-------------------PLDLA------------------ ------------DYTYDLAEE-------------------------DDSEPLNYKDP--- ----------------------C-------KA-------AAFL-GDIALDEED------- ------------LRAF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QVQQAAD-----------------------LRQHTARKSSIKAA------ --------VPG-NTSTPSC--------------------------QSTNGQPQR------ ------------------------GACGRW--RGR--------SRSRRAATSRPERVWPD GVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYN FLKM-EPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVN---GVKPPIGQRTR LSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGY---SAHMHCVWRISVTPGEKII LNFTSLDLYRS---RLC---WYDYVEVRDGFWRKAPLRGRFCG-SKLPEP-----IVSTD SRLWVEFRSS--SNWVG--KGFFAVYEAICGGDVK-KDY--GHIQSPNYPDDYRPSKVCI WRIQVS-EGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGR-----YCGYEKPD DIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDP GYELAPDKRRC--------EAACGGFLTKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RISLQFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGSEKPEVI-TSQYNNM RVEFKSDNTVSKKGFKAHFFS--DK--DECSKDNG----GCQQDCVNTFGSYECQCRSGF VLHDNKH---DCKEAG-CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTF MEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQR KGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEE-GYGVELVFQT FEVEEETDCGYDYMELFDGYD----STAPRL-GRYCGSGPPE---EVYSAGDSVLVKFHS DDTITKKGFHLRYTSTKFQDT------LHSRK---------------------------- ----------------------------------- >XP_038291401.1 bone morphogenetic protein 1 isoform X1 [Canis lupus familiaris] ------------------------------------------------------------ --------------------------------------MPGVARLP-------------- ----LP----LL----------------------LWL-------------LLLP------ --------------RPGR-------------------PLDLA------------------ ------------DYTYDLGEE-------------------------DDSEPVNYKDP--- ----------------------C-------KA-------AAFL-GDIALDEED------- ------------LTAF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QVQQVAD-----------------------LRQRTTHRSSIKTAVTYY-- --YCGRLPTPG-NSSAFNC--------------------------QSTSGQLQR------ ------------------------RSRGRW--RSR--------SRSRRAATSRPERVWPD GVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYN FLKM-ELQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVN---GVKPPIGQRTR LSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGY---SAHMHCVWRISVTPGEKII LNFTSMDLYRS---RLC---WYDYVEVRDGFWRKAPLRGRFCG-GKLPEP-----IVSTD SRLWVEFRSS--SNWVG--KGFFAVYEAICGGDVK-KDN--GHIQSPNYPDDYRPSKVCI WRIQVS-EGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSETSTLIGR-----YCGYEKPD DIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDP GYELAPDKRRC--------EAACGGFLTKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RISLQFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGSEKPEVI-TSQYNNM RVEFKSDNTVSKKGFKAHFFS--DK--DECSKDNG----GCQQDCVNTFGSYECQCRSGF VLHDNKH---DCKEAG-CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTF MEMDIESQPECAYDHLEVYDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQR KGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEE-GYGVELVFQT FEVEEETDCGYDYMELFDGYD----STAPRL-GRYCGSGPPE---EVYSAGDSVLVKFHS DDTITKKGFHLRYTSTKFQDT------LHSRK---------------------------- ----------------------------------- >XP_003823651.1 bone morphogenetic protein 1 isoform X1 [Pan paniscus] ------------------------------------------------------------ --------------------------------------MPGVAR---------------- ----LP----LL----------------------LGL-------------LLLP------ --------------RPGR-------------------PLDLA------------------ ------------DYTYDLAEE-------------------------DDSEPLNYKDP--- ----------------------C-------KA-------AAFL-GDIALDEED------- ------------LRAF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QVQQAAD-----------------------LRQHTARKSSIKAA------ --------VAG-NTSTPSC--------------------------QSTNGQPQR------ ------------------------GACGRW--RGR--------SRSRRAATSRPERVWPD GVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYN FLKM-EPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVN---GVKPPIGQRTR LSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGY---SAHMHCVWRISVTPGEKII LNFTSLDLYRS---RLC---WYDYVEVRDGFWRKAPLRGRFCG-SKLPEP-----IVSTD SRLWVEFRSS--SNWVG--KGFFAVYEAICGGDVK-KDY--GHIQSPNYPDDYRPSKVCI WRIQVS-EGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGR-----YCGYEKPD DIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDP GYELAPDKRRC--------EAACGGFLTKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RISLQFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGSEKPEVI-TSQYNNM RVEFKSDNTVSKKGFKAHFFS--DK--DECSKDNG----GCQQDCVNTFGSYECQCRSGF VLHDNKH---DCKEAG-CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTF MEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQR KGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEE-GYGVELVFQT FEVEEETDCGYDYMELFDGYD----STAPRL-GRYCGSGPPE---EVYSAGDSVLVKFHS DDTITKKGFHLRYTSTKFQDT------LHSRK---------------------------- ----------------------------------- >XP_023108277.1 bone morphogenetic protein 1 isoform X2 [Felis catus] ------------------------------------------------------------ --------------------------------------MPGVARLP-------------- ----LP----LL----------------------LWL-------------LLLA------ --------------RPGG-------------------PLDLA------------------ ------------DYTYDLGEE-------------------------EDSEPVNYKDP--- ----------------------C-------KA-------AAFL-GDIALDEED------- ------------LRAF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QVQQAED-----------------------LRQRATHRSSIKTT------ ----------G-NSSTPNC--------------------------QSTSGQPQR------ ------------------------RNRGRW--RSR--------SRSRRAATSRPERVWPD GVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYN FLKM-ELQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVN---GVKPPIGQRTR LSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGY---SAHMHCVWRISVTPGEKII LNFTSMDLYRS---RLC---WYDYVEVRDGFWRKAPLRGRFCG-GKLPEP-----IVSTD SRLWVEFRSS--SNWVG--KGFFAVYEAICGGDVK-KDN--GHIQSPNYPDDYRPSKVCI WRIQVS-EGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGR-----YCGYEKPD DIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDP GYELAPDKRRC--------EAACGGFLTKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RISLQFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGSEKPEVI-TSQYNNM RVEFKSDNTVSKKGFKAHFFS--DK--DECSKDNG----GCQQDCVNTFGSYECQCRSGF VLHDNKH---DCKEAG-CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTF VEMDIESQPECAYDHLEVYDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQR KGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEE-GYGVELVFQT FEVEEETDCGYDYMELFDGYD----STAPRL-GRYCGSGPPE---EVYSAGDSVLVKFHS DDTITKKGFHLRFTSTKFQDT------LHSKK---------------------------- ----------------------------------- >XP_014948597.2 bone morphogenetic protein 1 isoform X3 [Ovis aries] ------------------------------------------------------------ --------------------------------------MPGVARPP-------------- ----LP----LL----------------------LWL-------------LLLA------ --------------RPGR-------------------PLDLA------------------ ------------DYTYDLGEE-------------------------DDAEPLNYKDP--- ----------------------C-------KA-------AAFL-GDIALDEED------- ------------LRAF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QVQQAAD-----------------------LRQRATRRSSIKAAGTL--- --------VSG-NSSTLNS--------------------------QNASMKPQR------ ------------------------RSRGRW--KSR--------SRSRRAATSRPERVWPD GVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYN FLKM-EVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVN---GVKPPIGQRTR LSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGY---SAHMHCVWRISVTPGEKII LNFTSMDLYRS---RLC---WYDYVEVRDGFWRKAPLRGRFCG-GKLPEP-----IVSTD SRLWVEFRSS--SNWVG--KGFFAVYEAICGGDVK-KDN--GHIQSPNYPDDYRPSKVCV WRIQVS-EGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGR-----YCGYEKPD DIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDP GYELAPDKRRC--------EAACGGFLTKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RISLQFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGSEKPEVI-TSQYNNM RVEFKSDNTVSKKGFKAHFFS--DK--DECSKDNG----GCQQDCVNTFGSYECQCRSGF VLHDNKH---DCKEAG-CDHKVTSSSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTF MEMDIESQPECAYDHLEVYDGRDAKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQR KGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEE-GYGVELVFQT FEVEEESDCGYDYMELFDGYD----STAPRL-GRYCGSGPPE---EVYSAGDSVLVKFHS DDTITKKGFHLRYTSTKFQDT------LHSRK---------------------------- ----------------------------------- >XP_030869708.1 bone morphogenetic protein 1 isoform X1 [Gorilla gorilla gorilla] ------------------------------------------------------------ --------------------------------------MPGVAR---------------- ----LP----LL----------------------LGL-------------LLLP------ --------------RPGR-------------------PLDLA------------------ ------------DYTYDLAEE-------------------------DDSEPLNYKDP--- ----------------------C-------KA-------AAFL-GDIALDEED------- ------------LRVF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QVQQAAD-----------------------LRQHTARKSSIKAA------ --------VPG-NISTPSC--------------------------QSTNGQPQR------ ------------------------GACGRR--RGR--------SRSRRAATSRPERVWPD GVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYN FLKM-EPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVN---GVKPPIGQRTR LSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGY---SAHMHCVWRISVTPGEKII LNFTSLDLYRS---RLC---WYDYVEVRDGFWRKAPLRGRFCG-SKLPEP-----IVSTD SRLWVEFRSS--SNWVG--KGFFAVYEAICGGDVK-KDY--GHIQSPNYPDDYRPSKVCI WRIQVS-EGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGR-----YCGYEKPD DIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDP GYELAPDKRRC--------EAACGGFLTKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RISLQFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGSEKPEVI-TSQYNNM RVEFKSDNTVSKKGFKAHFFS--DK--DECSKDNG----GCQQDCINTFGSYECQCRSGF VLHDNKH---DCKEAG-CDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTF MEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQR KGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEE-GYGVELVFQT FEVEEETDCGYDYMELFDGYD----STAPRL-GRYCGSGPPE---EVYSAGDSVLVKFHS DDTITKKGFHLRYTSTKFQDT------LHSRK---------------------------- ----------------------------------- >XP_021154607.1 bone morphogenetic protein 1 [Columba livia] ------------------------------------------------------------ --------------------------------------M--------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------------------QESRRAATSRPERVWPD GVIPYVISGNFSGSQRAIFRQAMRHWEKHTCVTFLERND----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDDHVSIIRENIQPGQEYN FLKM-EPEEVESLGETYDFDSIMHYARNTFSRGIFLDTILPKYDVN---GVRPAIGQRTR LSKGDIAQARKLYRCPACGETLQDSQGNFSSPEFPNGY---SAHMHCVWRISVTPGEKII LNFTTLDLYRS---RLC---WYDYVEVRDGFWRKATLRGNQTG-SSQPARRHCPHLLPNR GMLGVQA--------AG--QGGFSSLTAICGGDVK-KDN--GHIQSPNYPDDYRPSKVCI WKITVS-EGFHVGLTFQSFEIERHDSCAYDYLEIRDGSSESSSLIGR-----YCGYDKPD DIKSTSNKLWMKFVSDGSINKAGFAVNFFKEVDECSRPNNGGCEQRCINTLGSYKCACDP GYELASDKRRC--------EAACGGFLTKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RISLQFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGAEKPDVI-TSQYNNM RIEFKSDNTVSKKGFKAHFFS--DK--DECSKNNG----GCQHECLNSFGSYECQCRSGF VLHDNKH---DCKEGG-------------SAP---------------------------- ------------------------------RFCGAKEPEPLISSSNKMFLKFVSDNSVQK KGFEATHATVCGGQVHAEVKTKDLYSHAQFGDNNYPGGSDCEWVIMAEE-GYGVELIFQT FEIEEEADCGYDYMELFDGYD----GTAPRL-GRFCGSGPPE---EIYSAGDSVMIRFHS DDTINKKGFHLRYTSTKFQDT------LHTKK---------------------------- ----------------------------------- >XP_017907774.1 PREDICTED: bone morphogenetic protein 1 isoform X1 [Capra hircus] ------------------------------------------------------------ --------------------------------------MPGVARPP-------------- ----LP----LL----------------------LWL-------------LLLA------ --------------RPGR-------------------PLDLA------------------ ------------DYTYDLGEE-------------------------DDAEPLNYKDP--- ----------------------C-------KA-------AAFL-GDIALDEED------- ------------LRAF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QVQQAAD-----------------------LRQRATRRSSIKAAGTL--- --------VSG-NSSTVNS--------------------------QNASMKPQR------ ------------------------RSRGRW--KSR--------SRSRRAATSRPERVWPD GVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYN FLKM-EVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVN---GVKPPIGQRTR LSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGY---SAHMHCVWRISVTPGEKII LNFTSMDLYRS---RLC---WYDYVEVRDGFWRKAPLRGRFCG-GKLPEP-----IVSTD SRLWVEFRSS--SNWVG--KGFFAVYEAICGGDVK-KDN--GHIQSPNYPDDYRPSKVCV WRIQVS-EGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGR-----YCGYEKPD DIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDP GYELAPDKRRC--------EAACGGFLTKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RISLQFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGSEKPEVI-TSQYNNM RVEFKSDNTVSKKGFKAHFFS--DK--DECSKDNG----GCQQDCVNTFGSYECQCRSGF VLHDNKH---DCKEAG-CDHKVTSSSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTF MEMDIESQPECAYDHLEVYDGRDAKAPVLGRFCGSKKPEPVLATSNRMFLRFYSDNSVQR KGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEE-GYGVELVFQT FEVEEESDCGYDYMELFDGYD----STAPRL-GRYCGSGPPE---EVYSAGDSVLVKFHS DDTITKKGFHLRYTSTKFQDT------LHSRK---------------------------- ----------------------------------- >XP_025066133.1 bone morphogenetic protein 1 [Alligator sinensis] ------------------------------------------------------------ --------------------------------------MAGDPE---------------- ----RP----VE----------------------LSK-------------LLG------- ----------------GY------------------GGYDTH------------------ ------------DDIETASDLLWMRLVSDSSINKATASFSVTFKVTTEAASLGGKGALHW DLLWIMRCLLLTKLNSIITSSRCLKEYLLNKN-------SVFL-GDIALDEED------- ------------LRMF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QADRITD-----------------------LTRHTMLRVAT--------- ------------NSSGSNT--------------------------NNTRLRPRR------ -----------------------HRKRHGWLVRQR--------SRSRRAATSRPERVWPD GVIPYVISGNFSGTQRAIFRQAMRHWEKFTCVTFLERTE----EDSYIIFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDDHVAIIKENIQLGQEYN FLKM-EPEEVESLGETYDFDSIMHYARNTFSRGIFLDTILPKYEVQ---GLRPSIGQRTR LSKGDISQARKLYRCPDCGETLQESQGNFSSPDFPNGY---AAHKHCVWRISVTPGEKII LNFTTLDIYRS---RLC---WYDYVEVRDGFWRKATLRGRFCG-NKLPEP-----IISTD SRLWIEFRSS--SNWVG--KGFFAAYEAICGGEVK-KDN--GHIQSPNYPDDYRPSKVCI WKITVS-PGFHVGIIFQSFEIERHDNCAYDYLEIRDGPSESSKELGR-----YCGYDKPD DIKTTSNKVWMKFVSDGSINKAGFSVTFFKEADECSRSDNGGCEQRCVNTLGSYKCACDP GYELAADKRRC--------EAACGGFLTKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RISLKFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGAEKPDVI-TSQYNNM RIEFKSDNTVSKKGFKAHFFS--DK--DECSKDNG----GCQHECLNTFGTYMCQCRSGF VLHDNKH---DCKEAG-CDHKVTSISGTITSPNWPDKYPTKKECTWALTTTAGHRIQLTF TELDIESHQECTYDHLEAYNGKDAKAPVLGRFCGAKKPEPIMSTSNKMFLKFFSDNSVQR KGFQASHTTVCGGQMRAEVKTKDLYSHAQFGDNNYPSGTDCEWVIMAEE-GYGVELIFQT FEIEEEADCGYDYMELFDGYD----GSAPRL-GRYCGSGPPE---VVYSAGDSVMIKFHS DDTINKKGFHLRYTSTKFQDT------LHTRK---------------------------- ----------------------------------- >XP_019347110.1 PREDICTED: bone morphogenetic protein 1 [Alligator mississippiensis] ------------------------------------------------------------ --------------------------------------MAGGRA---------------- ----RC----LL----------------------LAF-------------AVL------- ----------------GR-------------------ALDVA------------------ ------------DYP-DYAE--------------------------PEPEPLDYKDP--- ----------------------C-------KA-------AAFL-GDIALDEED------- ------------LRMF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QADRITD-----------------------LTRHTTLRVAT--------- ------------NSSGSNT--------------------------NNTRLRPRR------ -----------------------HRKRHGWLVRQR--------SRSRRAATSRPERVWPD GVIPYVISGNFSGNQRAIFRQAMRHWEKFTCVTFLERTE----EDSYIIFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDDHVAIIKENIQLGQEYN FLKM-EPEEVESLGETYDFDSIMHYARNTFSRGIFLDTILPKYEVQ---GLRPSIGQRTR LSKGDISQARKLYRCPDCGETLQESQGNFSSPDFPNGY---AAHKHCVWRISVTPGEKII LNFTTLDIYRS---RLC---WYDYVEVRDGFWRKATLRGRFCG-NKLPEP-----IISTD SRLWIEFRSS--SNWVG--KGFFAAYEAICGGEVK-KDN--GHIQSPNYPDDYRPSKVCI WKITVS-PGFHVGIIFQSFEIERHDNCAYDYLEIRDGPSESSKELGR-----YCGYDKPD DIKTTSNKVWMKFVSDGSINKAGFSVTFFKEADECSRSDNGGCEQRCVNTLGSYKCACDP GYELAADKRRC--------EAACGGFLTKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RISLKFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGAEKPDVI-TSQYNNM RIEFKSDNTVSKKGFKAHFFS--DK--DECSKDNG----GCQHECLNTFGTYMCQCRSGF VLHDNKH---DCKEAG-CDHKVTSISGTITSPNWPDKYPTKKECTWALTTTAGHRIQLTF TELDIESHQECTYDHLEAYNGKDAKAPILGRFCGAKKPEPILSTSNKMFLKFFSDNSVQR KGFQASHTTVCGGQMRAEVKTKDLYSHAQFGDNNYPSGTDCEWVIMAEE-GYGVELIFQT FEIEEEADCGYDYMELFDGYD----GSAPRL-GRYCGSGPPE---VVYSAGDSVMIKFHS DDTINKKGFHLRYTSTKFQDT------LHTRK---------------------------- ----------------------------------- >XP_020755633.1 bone morphogenetic protein 1 [Odocoileus virginianus texanus] MGESEGPRTRESDSRRRG--DAARDEGGQSGAEAARSTRRR---------------VRRP RRGLG-------------PDTPGTG-------------APSPAPPPRAPRRRSPLRAGRL RA--LPASGWLL----------------------RVM-------------LLLA------ --------------RPGR-------------------PLDLA------------------ ------------DYTYDLGEE-------------------------DDAEPLNYKDP--- ----------------------C-------KA-------AAFL-GDIALDEED------- ------------LRAF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QVQQAAD-----------------------LRQHATRRSSIKAA------ --------VSG-NSSALNS--------------------------QNTSTKPQR------ ------------------------RSHGRW--RSR--------SRSRRAATSRPERVWPD GVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYN FLKM-EVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVN---GVKPPIGQRTR LSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGY---SAHMHCVWRISVTPGEKII LNFTSMDLYRS---RLC---WYDYVEVRDGFWRKAPLRGRFCG-GKLPEP-----IVSTD SRLWVEFRSS--SNWVG--KGFFAVYEAICGGDVK-KDN--GHIQSPNYPDDYRPSKVCV WRIQVS-EGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGR-----YCGYEKPD DIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDP GYELAPDKRRC--------EAACGGFLTKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RISLQFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGSEKPEVI-TSQYNNM RVEFKSDNTVSKKGFKAHFFS--DK--DECSKDNG----GCQQDCVNTFGSYECQCRSGF VLHDNKH---DCKEAG-CDHKVTSSSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTF MEMDIESQPECAYDHLEVYDGRDSKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQR KGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEE-GYGVELVFQT FEVEEETDCGYDYMELFDGYD----STAPRL-GRYCGSGPPE---EVYSAGDSVLVKFHS DDTITKKGFHLRYTSTKFQDT------LHSRK---------------------------- ----------------------------------- >XP_040202086.1 bone morphogenetic protein 1 isoform X1 [Rana temporaria] ------------------------------------------------------------ --------------------------------------MPWTGRA--------------- ----PP----LF----------------------LWL-------------LLLP------ ----------------GV------------------IPLGEE------------------ ------------DYTDLYTELD------------------------ESEEHIDYKDP--- ----------------------C-------KA-------AAFI-GDIALDEED------- ------------LALF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------KIDRIVD-----------------------LRNRTISTVSRPAR------ -----------------------------------------------NGTLSRT------ ------------------------GRRARTD-RRV--------SRGRRAATSRPERVWPH GIIPYVVSGNFTGSQKAIFRQAMRHWEKHTCVTFLERTD----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDHHVTIIRDNIQPGQEYN FLKM-EQEEVESLGETYDFDSIMHYAKNTFSRGIFLDTILPKYEVN---GVKPSIGQRTR LSVGDITQARKLYQCTACGDTLQDSQGNFSSPGYPNGY---SAYVHCVWRLSVTPGEKIM LNFTSLDVYRS---RLC---WYDYIEVRDGHWKKAPLIGRYCG-EKIPEP-----IISSD SRLWIEFRSS--SNYVG--KGFHAVYEALCGGEMK-KDN--GHIQSPNYPDDYRPNKSCV WKLRVS-EGFNIGVTFQSFEIERHDSCAYDYLEIRDGNTEFSPLIGR-----FCGYDKPD DLKSSSNQLWVKFVSDGSINKAGFSIHFFKEVDECSRPHKGGCEQRCVNTLGSYKCACEP GYELAPDKKSC--------EAACGGFLTKLNGSLTSP-GWPKEYPPNKNCIWQLVAPTQF RISLKFDKFETEGNDV----CKYDYVEIRSGLTADA-KLLGTFCGAELPPVI-TSQYNNM RIEFKSDNTVSKKGFRATYYS--DK--DECSRDNG----GCQHECTNTQGSYTCHCRSGF TLHENKH---DCKEAG-CNHKVLASNQNISSPNWPDSYPSKKECTWQVTSTAGHRVKLIV KEVDLESHQECIYDHVEVYSGTDAQSPVLKRLCGSKVPEPIIAPGSSMFVKFVSDNSVQK KGFLAELTTECGGTLQAEVRTKDLYSHAKFGDDIHPSATECIWHIVSEG-KYGVELVFQS FELEEEQDCGYDYIELYDGPT----EGAPRM-GRYCGSGPPE---EVYSTGESLTVRFHS DDSINKKGFHIRYTSTKFQDT------LNARK---------------------------- ----------------------------------- >XP_039272807.1 bone morphogenetic protein 1-like [Styela clava] MADFCRAKFRTEKAFFCADIDPSV---------CC----KR------------------- --GYFRSVKM----------ASGGC-----MERQRTN-MKFLKTKESLS-N-------VL LHKEIP----LMDEQRTLCSGCLNMRSTKTYRRRLTLFAAMAIYILP--LLLLQ-P---- --------TGVQGLAPGVTWSVVAGISVINFQIESVNSQE-------------------- ------------QTTIWVDQP-------------------------EESEDKILKDP--- ----------------------C-------KA-------PLFL-GDIALDEVD------- ------------VEDIFG------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------ETVQEFMDHVGNDDSIEARDTTEDDGDDKKSINSQKSKKHSVREA------ --------SKGLRQNDPSAVDLDEQALRNKTESELSRIPTLREIVRRRKHSKKTEGVKLD SGKR----RKNGRRG--------RKRRGRY--RSRIQRTEAVHKRMRRAATARPERIWPA GVIPYVISANFTGSQRAMFKQAMRHWEAQTCITFIERTD----EEAFIKFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHIEIIYKNIQPGQEYN FEKM-DSSEINSLGETYDYYSIMHYARNTFSKGMFLDTIKPRVDAN---GARPTIGQRTR LSDGDVAQAKKLYQCNTCGYTLQDTSGNITSPNYPQYY---PAESHCIWRISVTPGEKIV LDITSLDIYES---EGC---YYDFLEIRDGHWYRSPKIGQYCG-RSLPAT-----ITSTD SRLWLQFRTS--TYYQG--RGFTLKYEAVCGGTIR-KES--GQIQSPNYPDDYRPSKECI WKVVVD-EGFRVGLSFQAFEVERHDTCSYDYLEVRDGPTADSDLIGR-----FCGYDKPE DVKSTSNTLWIKFVSDGSVNKAGFAASFFKEIDECEDKRKSGCQQGCVNTLGSYKCVCDP GYELAADGRTC--------EAACGGSVTNLDGYITSP-NWPNEYPTNKKCVWQIVAPPQH KISIQFEKFELEGNEV----CKYDYVEIRSGLSDDA-KFHGRFCGLELPPVI-RSTINEM SLAFKSDDTVSKRGFKIKFFS--DK--DECAISNG----GCEHECVNTIGSYSCTCRNGY VLHTNKR---GCKEAG-CKHDIKTAVGEITSPNWPNKYPSRKECTWLIRTTPGHRVKVVF HEFELETQPECAYDHLELYDGSDSDQTVLGRYCGSKKPGTIVATTSIMFIKFFSDASVQK RGFSATHQTVCGGNLNASTRSKDLFSHPQYGDNNYISGQECDWIITADT-GLVVRLTFTA FEVEEETDCSYDFVEVYDGED----DSATRF-GRYCGSKALS---TIMSTSGSLLLRFHS DDTINKKGFHARYSSSSYEDI------SESSSTGRRI----------------------- ----------------------------------- >XP_038060664.1 bone morphogenetic protein 1 homolog isoform X1 [Patiria miniata] ------------------------------------------------------------ --------------------------------------MGPVTLNHHLH----------- ----RT----FV----------------------LSLC------LLP--CLLLTVH---- -----VQSSCAHDLKDGMKL--------SRHHNKMQDEGD-------------------- ------------PHVYW-----------------------------RSTVTEEFADP--- ----------------------C-------KA-------DGFL-GDIALTEEQ------- ------------YQQEIG------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------RYKQKLQEYKQ--------------------SKGIRKKTNKQHEEKQLAKE--- ------------EKRLAKE--------------------------RRKLQRKEKKAIKEE KREE----RRQSRRPHLETIQIVQEEEETE--RGTDEVTTETHHRVARAVTSRPERKWPY GVIPYVIDGNFTGSQRAMFKQAMRHWENYTCITFVERSP--TQHRNYIVFTYRSCGCCSF VGMRAEGAQAISIGKNCDKFGVVVHELGHVVGFWHEHTRPDRDDHVTIVKENILPGQEYN FNKL-LPEEVDSLGQPYDFASIMHYARNTFSRGIWLDTVIPQRDPDAVPRAEIEIGQRKQ LSEGDITQANLLYKCPACGRTLQETTGNFSSPGWPEQF---NSRESCVWRISVTPGETIV LTFEDFELVGS---DDC---WYHHVEVRDGHWRFSNVLGRFCG-SNIPPV-----IVSTD SRLWIELKSSPTGNAVS--RGFAAHYEAVCGGNIS-KES--GMLQSPNYPDDYRPDKSCV WYLTMP-EGFQVGLNFQSFEVERHDNCIYDYVEVRDGHEDDSPLIGK-----YCGYLMPE DIKSSSNKLRVKFVSDGTVNKGGFSADFFKEDDECSK-NNGGCEQICVNTIGSYRCECEP GFELKADGESC--------EVACGGFLTSLQGNITSP-SYPDLYPRDKNCVWHLVAPSLY RISLQFLSFELEGNDV----CKYDYVEVRSGLTEVG-DLHGKFCGDDIPDTI-TSRYNNM RIEFKSDSTVSRPGFFAMFFA--DI--DECEKNNG----DCQHVCVNTLGSYTCSCRNGF TLHENGH---DCKESG-CRHDIRSSHGEITSPNYPDNYPKRKECTWHIVATPGHKVELVF NDFDLEHHLECAYDHVVIYDGDSSEGHLLGRFCGTRIPDPVLANTNQMYITFFSDASVSR RGFFATHSTICGGVLQADYVSQKLYSHADYGDNNYGSQEDCEWTILAPQ-GYSVRLMFRS FDIEHETECDYDSLEVLDGDS----YDSERI-GRFCGHKIPD---DIISQGENLRLIFRS DDTISKKGFYAEYQIS-------------------------------------------- ----------------------------------- >XP_030834881.1 bone morphogenetic protein 1 homolog isoform X1 [Strongylocentrotus purpuratus] ------------------------------------------------------------ --------------------------------------MDLLYY---------------- ----------MT----------------------VSLL-----------GFIL------- ------------------------------------------------------------ ------------SLTTFIGET-------------------------TRALSDDVSSP--- ----------------------C-------KA-------SGFL-GDIALTEDD------- ------------YEREMI------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------RARHNREQY--------------------------------------------- ------------RRRILQE--------------------------RHTRTTGARHHI--- ------------------------KKRTIE--EAK--------VRHVRAVTARPERRWTD AVIPYEIDGNFTGSQRAMFKQAMRHWENYTCITFVERNPANSEHDNHIVFTYQACGCCSF VGRKGDGAQAVSVGKNCDKFGVVVHELGHVVGFWHEHTRPDRNEFVGIVHQNIVPGQEYN FRVL-DAAEVDSLGETYDFASIMHYARNTFSRGIWLDTILPRKDPES--GIRPEIGQRKH LSEGDIIQANLLYKCPSCGRTLLESTGNFSSPEWPGQY---DGDQTCVWRISVTPGETIS LQFTGFELVGS---DGC---WYNYLEVRDGHWRHSPLLGRFCG-ASLPDP-----ILSSD SRLWIELKSS--AHRYS--RGFAANYEAICGGHIE-RES--GTLQSPNYPDDYHPSKECV WLITMP-ANYTVGLSFQSFEIERHETCIYDYVEVRDGHEDTSPLIGR-----YCGYFIPD DIKSTGNKMMVTFVSDGSVNKGGFSADFFKEKDECAQPDQGGCMDVCVNTIGSYRCDCRP GYELSSDGRRC--------EVACGGLFTGLRGNISSP-SYPEPYPRDKNCVWQIVAPSNY RISLQFITFDLEGNEV----CKYDYVDVRSGLNEEG-TLHGKFCGNEIPETI-TSRFNNL RIDFRSDNTVAKEGFFANFFA--DV--DECEEGNG----GCQHICTNTLGSYTCSCRNGF TVHENLH---GCKESG-CRREIQSTTGIITSPNYPDNYPKRKECTWHISANPGHKIVLSF DDFDLEQHQECTYDRVQVFDGDSDEGQVLGRYCGATIPDAVVSSSNHMFIRFYSDASVSR SGFSATHSTQCGGRLEAELSAQRLYSHADYGDQNYENQESCEWTIVSPD-DHFIHLWFRS FDIEHETECNYDQVMILDGDN----HAAESF-GKFCGHRAPD---DIVSSGDSLMITFSS DDTINKKGFLAIFKLTDGELL------EGAGEEEEEIYYN-------------------- ----------------------------------- >CAE1240683.1 tok [Sepia pharaonis] ------------------------------------------------------------ --------------------------------------MLSSGSYLLLFV---------- ----------FL----------------------MLCMQFHCQGTVQ--GLSLP------ --------------EPKS---LPMHRISSKDPVSLYTEQD-------------------- ------------STNISYKQPT------------------------RKTSNDLYMDP--- ----------------------C-------KA-------AGFI-NDIALTDDD------- ------------VHDLMK------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------MWHNNIEVQVD----------DPNVRHPRKISEPVSKRRPRKKNKGSHRKR--- --KRCRKKDPKCNKRKSKD--------------------------TTKKNSPKQ------ ------------------------KPVSEA--SRS--------WRTRRAATARQDRLWEY GVIPYQIEANFSGPHKALFRLAMRHWENHTCITFVERTP--E-HEDYIVFTERPCGCCSY VGKRGNGAQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDDHVQIIYKNIMPGQEYN FNKL-TPADVNSLGEEYDYGSIMHYARNTFARATFVDTILPKRKY----GTR-DIGQRIK LSPGDIRQANRLYRCASCGRTLQAATGEFSHKPNQQRT---EEREVCEWRISATHGEKIV LNITSLDVPES---RNC---VTDYLEVRDGYYERSTKLGKFCG-KTVPGV-----LQSTD SRMWLRFVST--QK-KG--EGFVAKYEAICGGVIN-KSR--GTLTSPNSPDDYRANQECV WRITVP-KAYLVGLMFQSFEIENHDNCVYDYLEIRDGPDETSPSLGK-----FCGYKVPE DIKSSGNQLYVKFVSDGSVQKAGFSATFTEEYNECLT-DYHGCDHICVNTLGSYKCMCEI GYELHSDGRKC--------EDACGGYISIENGTFQSP-SFPDLYPTNKYCVWQIVAPKQH RITLNFSYFDLEGNNQ---DCEYDSVRVSNGLNSDT-KAIGIFCGSTLPDSI-TSSENSL RIEFSSDNSVQKTGFNATFFT--DK--DECALKNG----GCQQICRNTIGSYQCACQNGF TLHENKH---DCKEGG-CKHQIKTPSGNINSPKWPDFYPSRKDCVWTFTVTDGHRVKLEF EEFELEPHQECTYDHIEIFDGTSTNSRSLGRFCGNKIPPPTYSSGNTMFMIFYSDASVQR KGFSAMHSTVCGGHLLAKTEPKFIYSHAKYGDQNYDNAADCDWIIEAED-DQRIYVEFKA FEIEDESECMYDYVKLYDGKS----DTGSAI-GKYCGSNKPP---PVTSSGRILTIRFVT DDTVNWKGFSLTYRLAEDQST----GGGETQELPEVQG---------------------- ----------------------------------- >XP_006567027.2 tolloid-like protein 1 isoform X2 [Apis mellifera] ------------------------------------------------------------ --------------------------------------MVASQEKS-------------- ----EP----IM----------------------VDRNQYSMDGELE-GGFSFNA----- ---------RNEDARPGV----------RDEGVEFRLESTTPPT---KKRHSARKQG--- --------REASQTASNATKSMQ--------------------AFLRTSEELNVAFP--- ----------------------T-------ST-------EGTN-QMRNLNAEN------- ------------IEQVF------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------TIQPESS--------------------TRNTSKQRHRRHHRRRTPKR--- --RHRRRKIPLIRRDLDDSSDE----------------------VVSFHDRQLRSIQFYD MEHK--------WKH--------GGARKRE--RFS--------SRARRAATARKERVWDH GVIPYEIDGNFSGAHKALFKQAMRHWENFTCVKFVERVP--QEHPNYILFTERPCGCCSF VGKRGNGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVQIIRDNIMSGQEYN FNKL-TEDEVNSLGLPYDYDSIMHYAKNTFSRGTYLDTILPMEVHG---KKRPEIGQRLR LSEGDIAQTNLLYKCYKCGRTFQENSGSFGSPTHPNSSP-PSEGERCEWRITATHGERIV LNITSLDIFKS---NFC---RSDYLEIRDGYWYKSNVLGRYCGSGKIHEP-----VVSTG SRMLVTYVTS--NYQSG-HRGFTASYEAVCGGEIELEDT--GHLESPNYPDGYQSSKECV WKLSVP-QNFQVALKFQSFEIENHDNCVYDYVEVRDGHNADSPLIGV-----YCGYKIPP DIKSTGNKLLVKFVSDGSVQKAGFSATFMKEFDECVL-IDHGCEHNCINTLGGFECSCKP GYELHSDGKHC--------EDACGGVFEDSNGTITSP-SFPVTYPGNKDCVWEIIAPPQY RITLNFTHFDLEGTNARQQECEYDSVEVSSKLGDDILRKHGVFCGSRLPSLI-TSEGNSM RVTFTSDNSIQKTGFAAVFFT--DM--DECATNNG----GCQHECRNTIGSYQCSCHNGF TLHENGH---DCKEGG-CKYEIAAPMGTITSPNYPDYYPGLKDCVWHFVTKPGHRIKLVF KVFEMESHQECNYDHIAIYDGDSPDSHVLGKFCGTKEPHPILATGNQMYMVFKSDASVQR KGFFATHSTACGGHLVATNEIRHLYSHARYGVHNYDHRTDCDWAIEAPP-GKNVHLTFVT FQLESESDCNYDFVEVYSGLD----TSGLLY-GRFCGNSNTT---DFISINEALLVRFRT DDTISNKGFMALFVAVDRQDSGENYGGSEDEDADEENL---------------------- ----------------------------------- >NP_001287510.1 tolkin, isoform C [Drosophila melanogaster] ------------------------------------------------------------ ------------------------------MRRRRGTPLGVSWTNCVLLL---------- ----ATG---LL----------------------VVLISVHAKNPRPHRGLPAPAPAPVP ASVDQVATENAHRREPTVDGSVLQRLSGSDRAVDEDEDVDEDEDEGLKHQHLEHRQQFDA YLGTIRRLRRPYRSKYTIEQLMRL-------------------HVTPKVSGDIDMDP--- ----------------------C-------KA-------GGFM-GDIALPEGDSGPVVAH TPIDDEEQERQEVEQLLADSPSPVHDPPSVSGAANSGPTKFNATFQLDLEKLKQEVYHEG LQVEEEGLTDIIRKKTKLPSSGPVNLKAGQSQSQSQSANEPVKPGSESPSDYAQASSYKN EVLPPSEQRIHTDKPARLTLAEIGPKFSNKTQSLHRNVDTRKIQSDNKDIEDDSGNNFVA ERRPSQIVPTSLPEQRSTPAHVYSNAGGNGMQLDDEVDFLHSRGVVRRRHRRGPKQRRSN QHLEHEVKLQRLREELS----------RPVIEAHHHQSHHQKQAQHRQHHQSHHRKKHRR QQQHHRRRGQSTTQYVNHSPPG----------------------FNQSQQAQQQSVPEMD L-----------LKA--------ETSKDEE--PLR--------HRVARAVTAKKERIWDY GVIPYEIDGNFSGIHKALFKLAMRHWENSTCIKFVERDP--EIHPNYIVFTVRSCGCCSF VGKRGNGPQAISIGRNCDKFGIVVHELGHVVGFWHEHTRPDREKHVVIEHNNIMKGQDYN FNML-SPDEVDSLGMAYDYDSIMHYARNTFSKGTYLDTILPIEMKG---RKRPEIGQRLR LSQGDIAQANLLYKCPKCGRTFQESSGIFASPSHYTAGALSNETEHCEWRITATYGERVE LKLENMNIFKS---NNC---ETDYLEIRDGYFEKSPLIGRFCG-KVDKEV-----IRTES SRMLLTYVNT--HRIEG-FRGFKAEFDVVCGGELS-VDDAVGRLESPNYPLDYLPNKECV WKITVP-ESYQVALKFQSFEVENHDSCVYDYVEVRDGPGQDAPLIGV-----FCGYKPPP NMKSSGNSMYVKFVSDTSVQKAGFSAVFMKEVDECET-QNHGCEHECINTLGGYECSCRI GFELHSDKKHC--------EDACGGVIEYPNGTITSP-SFPEMYPLLKECIWEIVAPPKH RISLNFTHFDLEGTAHQQSDCGYDSVTVYSKLGENRLKRIGTFCGSSIPPTA-TSESNAL RLEFHSDKSIQRSGFAAVFFT--DI--DECAVNNG----GCQHECRNTIGSYICMCHNGY SMHENGH---DCKEGE-CKYEISAPFGTIFSPNYPDSYPPNADCVWHFITTPGHRIKLIF NEFDVESHQECTYDNVAVYDGESESSSVLGRFCGDKIPFPISSTSNQMYMVLKTDKNKQK NGFTASHSTACGGYLRATSQVQQFYSHARFGNQDYDDGMDCEWTIAAPD-NSYVQLIFLT FDIESSENCTFDYVQVFSDIDDVYGQYGPMY-GQYCGNVLPQ---DINSMTHSLLVRFKT DGSVPMKGFSASYVAVPNSGE------YDHSDEDVENSYSSEMVTPFPGSLKSIYIEDTQ EETDEYSDFSGNQLVFNGQYRGRYSLPKRYYSGKA >XP_031559878.1 tolloid-like protein 1 [Actinia tenebrosa] ------------------------------------------------------------ --------------------------------------MAWTA----------------- ----------MV----------------------VTVV-----------FLVCV------ ------------------------------------------------------------ ----------------------------------------------VNGDNEDY-DP--- ----------------------C-------KA-------DGIIQGDIATN---------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------RRQ--------MRTRRAATADRNRFWKD GMIPYDIEIDYTGEQKATILRAMRHWENFTCLSFIEKSD--Q-DDDYIYFHNGRCGCCSF VGRKGNGRQGISIGKNCDKFGIVVHEIGHVVGFWHEHTRPDRQEYVTIINENIKKGEEHN FQKL-TNRDIDSRNEDYDYGSIMHYGKYTFSTSKNHVTILPKRNPFS--RMVPIIGQREK LSNGDVRQTHKMYRCPECGRTLQEPKGSFTSPGYPKPY---SQNKHCEWRISVTPGERIV LNFTKFNLRKASSNRGC---KHDFLEIRDGHGRKSNLIGRYCG-KKFPPT-----IWSTG SRLWIKFKSG--SSEIKPEFGFAAKYETRCGGPIR-KTH--GTIQSPNYPSWYPSKKECV WTIELPSKNLNVGVRFVAFDIEAHEQCDYDYLQLFNGPDTSSPSLGK-----FCGKTIPS DIKSNSSYLTLKFNSDTSINKPGFYITFFSERNECKV-NNGGCSQICRNTLGHYECECYP GFELHSNGKDC--------EAACGGILSDRNGTIMSP-SYPANYPKNKGCTWQITGLKGQ RVSLKFKEFKLEGSAN--GNCRYDYVEIRD---ENN-KVLKKLCGSSIPKTI-TSPSNVM FVDFRSDHTQSRKGFLAMYYS--DE--DECQKRKG----GCQHICVNTIGSYRCACKPGF TLHSNKH---SCKEASECSATLTTQTGLIMSPNYPGVYQHKKDCTWKIVVKPGSHVELNF RFLQIEEANDCRYDYVEIFSGTGGQAESIGRVCGNSLPSPVLSKAHKLMIKFHSDALIAK RGFKARYNAICGAKLNAINTARTFYSHPAYGDDDYSPSVKCRWTISTRN-G-FVKLRFKE FEVEKEKYCSYDGVTIRDGSN----ATSPLL-GKICGNSAKNAKREFLSTSNKMFIEFVS DLTTQKKGFIAEYVRVKRKGR------NRSKEYKTGKI---------------------- ----------------------------------- >NP_001360030.1 Zinc metalloproteinase nas-39 [Caenorhabditis elegans] ------------------------------------------------------------ --------------------------------------MRFSAN---------------- ----IA----II----------------------VNII-----------FLFIV------ ------------------------------------------------------------ ---------------------------------------------------VEFVLP--- ----------------------TFI-----RS------------GDV------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------RFRRYY--RNN--------GRVSRAATAKKERIWPE GIIPFVIASNFSGEHQHLFLRAMRHWENFTCVSFVPRQP--H-HKHYITFTVDKCGCCSY VGRRGEGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDMYVDIFYKSIQTGQDYN FEKS-KPEEVDSLGEPYDFSSIMHYARDTFSRGAFYDTILPKPNS----GFRLEIGQRVQ LSEGDIRQTKKLYKCAECGGTLMQESGNLAI----------QHAGVCTWHIISPQGHTIF LNITGSTLSPPS--SLCGKEEDNVITVRDGVSISSPVLDRICGGDSLFRT-----IASSG NRMLIQVRSS--TPAAS--LPF-ATYYAICGGPIY-ANE--GVIHSPKYPESYPPNSDCQ WTIHVD-ENSQVAIEFVYFHLEQHKECIYDRLILTEGISKNSKKDGKEMSETFCGLIEKK TIVSKTNQISLRFFSDNSVQKTGFELRFTKELNECAT-DKNICHHYCVNTVGGFKCACRV GYSLSSNGFSC--------DSTCGGYLKASNGSISSP-NFPEMYPNSKTCIWEIEAPDGY HIFLNFTKFNVEGMKT---ECAYDYVKIGDS---------EKLCGEYHEALLFTTPRNRV RIEFSSDSSVERDGFFANFIA--DF--DECQNDNA----GCEHTCQNRLGSYVCTCNPGY ILAEDKH---NCKEGS-CFFEVNAPAGDINSPNYPNDYPKGQNCSWHFVTTPGHRLMLTF SSFQVEEHAQCKYDAVSVYDGGDGSAQLAGVFCGLAPPPLLLSSSNELYLTFSSDASVSR RGFQAHYTSLCGGRLTAESTPGHIYSHATFSDSKYGKNQDCSWIVRAKSPGRGVRIQFST FNIESEEGCQYDYIEIYDGPE----ATLERLVGRFCGDTSPE---VITSTGPELLLIMHT DNAEEEKGFVAEYREAPRSSSTKRTFVSKTRHSPLEEP-----------------IHDRN E---------------------------------- >XP_043308815.1 bone morphogenetic protein 1 isoform X1 [Cervus canadensis] ------------------------------------------------------------ --------------------------------------MPGVARPP-------------- ----LP----LL----------------------LWL-------------LLLA------ --------------RPGR-------------------PLDLA------------------ ------------DYTYDLGEE-------------------------DDAEPLNYKDP--- ----------------------C-------KA-------AAFL-GDIALDEED------- ------------LRAF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QVQQAAD-----------------------LRQRATRRSSIKAA------ --------VSG-NSSTLNS--------------------------QNTSTKPQS------ ------------------------RSHGRW--RSR--------SRSRRAATSRPERVWPD GVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYN FLKM-EVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVN---GVKPPIGQRTR LSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGY---SAHMHCVWRISVTPGEKII LNFTSMDLYRS---RLC---WYDYVEVRDGFWRKAPLRGRFCG-GKLPEP-----IVSTD SRLWVEFRSS--SNWVG--KGFFAVYEAICGGDVK-KDN--GHIQSPNYPDDYRPSKVCV WRIQVS-EGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGR-----YCGYEKPD DIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDP GYELAPDKRRC--------EAACGGFLTKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RISLQFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGSEKPEVI-TSQYNNM RVEFKSDNTVSKKGFKAHFFS--DK--DECSKDNG----GCQQDCVNTFGSYECQCRSGF VLHDNKH---DCKEAG-CDHKVTSSSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTF MEMDIESQPECAYDHLEVYDGRDSKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQR KGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEE-GYGVELVFQT FEVEEETDCGYDYMELFDGYD----STAPRL-GRYCGSGPPE---EVYSAGDSVLVKFHS DDTITKKGFHLRYTSTKFQDT------LHSRK---------------------------- ----------------------------------- >KAF4019395.1 hypothetical protein G4228_011326 [Cervus hanglu yarkandensis] MDVGSKEVLMESPP------DYSAVPGGRLRIPCCPVNIKRLLIVVVVVVLVVVVVVGAL LMGLHMSQKHTEMLLIAYKPAPGTCCYIMKMAPQSIPSLEALTRKL-------------- ----QN----LQ----------------------VGV-------------WGLR------ --------------KPQR-------------------DSEDP------------------ ------------GAKGSCADW-------------------------QEADPVDSTGT--- ----------------------G-------PGEMGAVGRAAFL-GDIALDEED------- ------------LRAF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QVQQAAD-----------------------LRQRATRRSSIKAA------ --------VSG-NSSTLNS--------------------------QNTSTKPQS------ ------------------------RSHGRW--RSR--------SRSRRAATSRPERVWPD GVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYN FLKM-EVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVN---GVKPPIGQRTR LSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGY---SAHMHCVWRISVTPGEKII LNFTSMDLYRS---RLC---WYDYVEVRDGFWRKAPLRGRFCG-GKLPEP-----IVSTD SRLWVEFRSS--SNWVG--KGFFAVYEAICGGDVK-KDN--GHIQSPNYPDDYRPSKVCV WRIQVS-EGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGR-----YCGYEKPD DIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDP GYELAPDKRRC--------EAACGGFLTKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RISLQFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGSEKPEVI-TSQYNNM RVEFKSDNTVSKKGFKAHFFS--DK--DECSKDNG----GCQQDCVNTFGSYECQCRSGF VLHDNKH---DCKEAG-CDHKVTSSSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTF MEMDIESQPECAYDHLEVYDGRDSKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQR KGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEE-GYGVELVFQT FEVEEETDCGYDYMELFDGYD----STAPRL-GRYCGSGPPE---EVYSAGDSVLVKFHS DDTITKKGFHLRYTSTKFQDT------LHSRK---------------------------- ----------------------------------- >KAB0373058.1 hypothetical protein FD755_014717 [Muntiacus reevesi] ------------------------------------------------------------ --------------------------------------MPGVARPP-------------- ----LP----LL----------------------LWL-------------LLLA------ --------------RPGR-------------------PLDLA------------------ ------------DYTYDLGEE-------------------------DDAEPLNYKDP--- ----------------------C-------KA-------AAFL-GDIALDEED------- ------------LRVF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QVQQAAD-----------------------LRQRATRRSSIKAA------ --------VSG-NSSTLNS--------------------------QNTSTKPQR------ ------------------------RSHGRW--RSR--------SRSRRAATSRPERVWPD GVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTD----EDSYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYN FLKM-EVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVN---GVKPPIGQRTR LSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGY---SAHMHCVWRISVTPGEKII LNFTSMDLYRS---RLC---WYDYVEVRDGFWRKAPLRGRFCG-GKLPEP-----IVSTD SRLWVEFRSS--SNWVG--KGFFAVYEAICGGDVK-KDN--GHIQSPNYPDDYRPSKVCV WRIQVS-EGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGR-----YCGYEKPD DIKSTSSRLWLKFVSDGSINKAGFAVNFFKEGMLVRGRGR--------------KCHRSP GRRQDSPRLRGGDTAFLVPPAACGGFLTKLNGSITSP-GWPKEYPPNKNCIWQLVAPTQY RISLQFDFFETEGNDV----CKYDFVEVRSGLTADS-KLHGKFCGSEKPEVI-TSQYNNM RVEFKSDNTVSKKGFKAHFFS--DK--DECSKDNG----GCQQDCVNTFGSYECQCRSGF VLHDNKH---DCKEAG-CDHKVTSSSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTF MEMDIESQPECAYDHLEVYDGRDSKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQR KGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEE-GYGVELVFQT FEVEEETDCGYDYMELFDGYD----STAPRL-GRYCGSGPPE---EVYSAGDSVLVKFHS DDTITKKGFHLRYTSTKFQDT------LHSRK---------------------------- ----------------------------------- >XP_004072530.1 bone morphogenetic protein 1 [Oryzias latipes] ------------------------------------------------------------ --------------------------------------MDLSVR---------------- ----CL----FL----------------------LSCL-----------GVIL------- ----------------AI-------------------DLDAA------------------ ------------DPGYYVEPT-------------------------ATSEAIDYKDP--- ----------------------C-------KA-------VAFL-GDIALDEED------- ------------MRLF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------KVDRIID-----------------------LAQRTVQNVNHTDE------ ----------G-S-----D--------------------------HSGNANN-------- --------------------------------QGS--------QRRKRAATSRPERVWPE GVIPYVISGNFSGSQRAVFRQAMRHWEKHTCVTFIERTQ----EESYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDEHVSIIKDNIQPGQEYN FLKM-EPGEVDSLGEVYDFDSIMHYARNTFSRGIFLDTILPRYDVN---GVRPPIGQRTR LSKGDIAQARKLYKCSKCGESLQDSSGNFSSPGFPNGY---SAYMHCIWRISVTPGEKII LNFTSMDLYRS---HLC---WYDHVEIRDGYWRKAPLKGRFCG-DKLPEP-----IISTD SRLWIEFRSS--SNWVG--KGFSAVYEAICGGDVK-RDN--GQIQSPNYPDDYRPNKACI WKISVS-EGYHVGLTFQSFEIERHDSCAYDYLEVRDGISENSPLLGR-----FCGYDKPD DIKTSSNHLWMKFVSDGSVNKAGFAANFFKEMDECSKPDNGRCEQRCVNTLGSYKCACDP GYELAADKRSC--------EAACGGFITKLNGSITSP-GWPREYPPNKNCIWQLVAPTQY RITLLFDVFETEGNDV----CKYDFVEVRSGLSADS-KPHGKFCGSEKPEAI-TSQYNNM RIEFKSDNTVSKKGFKAQFFS--DK--DECSKENG----GCQHDCVNTFGSYRCQCRSGF VLHENKH---DCKEAG-CDHTVNSVSGAITSPNWPDKYPSKKACTWALSTTPGHRIKIAF NEIDMEAHLDCAYDHIQIYDGRDAKAPSLGRFCGSKKPQPIISSGNKLFIRFFSDNSVQK KGFDASHSAECGGILKAEVKTKDLFSHAQFGDNNYPGASDCEWVISAEK-GYGVELIFQT FEIEEEADCGYDYMELFDGAD----TKSPRL-GRYCGSGPPE---EIYSAGDSIVIKFHS DDTINKKGFHVRYTSTKFQDT------LHSRK---------------------------- ----------------------------------- >XP_030273707.1 bone morphogenetic protein 1 [Sparus aurata] ------------------------------------------------------------ --------------------------------------MDLTAR---------------- ----CL----FL----------------------LYCL-----------GVIL------- ----------------AI-------------------DLEAI------------------ ------------DPGYYVEST-------------------------ATSEAIDYKDP--- ----------------------C-------KA-------VAFL-GDIALDEED------- ------------MRSF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------KVDRVID-----------------------LAQRTVYTVNHTDS------ ----------G-S-----T--------------------------NQSSQNR-------- --------------------------------QGS--------HRRKRAATSRPERVWPE GVIPYVISGNFSGSQRAIFRQAMRHWEKHTCVTFIERTQ----EESYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDEHVSIIRDNIQPGQEYN FLKM-EPGEVDSLGEVYDFDSIMHYARNTFSRGIFLDTILPRYDVN---GVRPPIGQRTR LSKGDIAQARKLYKCSRCGDSLQDSSGNFSSPGFPNGY---SAYMHCIWRISVTPGEKII LNFTSMDLYRS---HLC---WYDHVEIRDGYWRKAPLKGRFCG-DKLPEP-----IISTD SRLWIEFRSS--SNWVG--KGFSAVYEAICGGEVK-KDN--GQIQSPNYPDDYRPNKVCV WKITVA-QGYHVGLTFQSFEIERHDSCAYDYLEVRDGNSENSPLLGR-----FCGYDKPD DIKTSSNQLWMKFVSDGSVNKAGFAANFFKEMDECSKPDNGRCEQRCVNTLGSYKCACDP GYELAADKRSC--------EAACGGFITKLNGSITSP-GWPREYPPNKNCIWQLVAPTQY RITLLFDVFETEGNDV----CKYDYVEVRSGLSADS-RLHGKFCGAEKPEAI-TSQYNNM RIEFKSDNTVSKKGFKAQFFS--DK--DECSKENG----GCQHECVNTFGSYSCQCRSGF VLHENKH---DCKEAG-CDHTVNSVSGTITSPNWPDKYPSKKACTWALTTTPGHRIKIAF NEIDMEAHLECAYDHIEIYDGRDGKAPSMGRFCGTKKPPPITSSGNKLFVRFFSDNSVQK KGFEASHTAECGGRLKAEVKTKDLFSHAQFGDNNYPGASDCQWVISAEK-GYGVELIFQT FEIEEEADCGYDYMELFDGAD----TKSPRL-GRYCGSGPPE---EIYSAGDSIVIKFRS DDTINKKGFHVRYTSTKFQDT------LHSRK---------------------------- ----------------------------------- >XP_015827829.1 PREDICTED: bone morphogenetic protein 1 [Nothobranchius furzeri] ------------------------------------------------------------ --------------------------------------MDLSVS---------------- ----CW----LL----------------------LSCI-----------GAIL------- ----------------AI-------------------DLEAI------------------ ------------DPGFYVEPS-------------------------ATSEAIDYKDP--- ----------------------C-------KA-------AAFL-GDIALDEED------- ------------LKNF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------KVDRIID-----------------------LAQRTVQTFNHTDA------ ----------G-S--------------------------------DNRSQNR-------- --------------------------------QSP--------QRRKRAATSRLERVWPE GVIPYVISGNFSGSQRAIFRQAMRHWEKHTCVTFIERTQ----EESYIVFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDEHVSIIRDNIQQGQEYN FLKM-EPGEVDSLGEVYDFDSIMHYARNTFSRGIFLDTILPRYDVN---GVRPPIGQRTR LSKGDIAQARKLYKCSKCGDSLQESSGNFSSPGFPNGY---SAYMHCIWRISVTPGEKII LNFTSMDLYRS---HLC---WYDHVEIRDGYWRKAPLKGRFCG-DKLPEP-----IISTD SRLWIEFRSS--SNWVG--KGFSAVYEAICGGEVK-RDN--GQIQSPNYPDDYRPNKVCV WKISVS-QGFHVGLTFQSFEIERHDSCAYDYLEVRDGLSENSPLLGR-----FCGYDKPD DIKTSSNHLWMKFVSDGSVNKAGFAANFFKETDECSKPDNGRCEQRCVNTLGSYKCACDP GYELAADKRSC--------EAACGGFITKLNDSITSP-GWPREYPPNKNCIWQLVAPTQY RITLLFDVFETEGNDV----CKYDYVEVRSGLSADS-RLHGKFCGAEKPEAI-TSQYNNM RIEFKSDNTVSKKGFKAQFFS--DK--DECSKENG----GCQHECVNTFGSYSCQCRSGF VLHENKH---DCKEAG-CDHTVNSVNGVITSPNWPDKYPSKKACTWALTTTPGHRIKIAF NEIDMEPHLECAYDHIEVYDGRDGKSPSLGRFCGSKKPPPIESSSNKLFIRFFSDNSVQK KGFEASHSAECGGRLKAEVKTKDLFSHAQFGDNNYPGASDCQWVISAEK-GYGVELIFQT FEIEEEADCGYDYMELFDGAD----TKSPRL-GRYCGSGPPE---EIYSAGDSIVIKFHS DDTINKKGFHVRYTSTKFQDT------LHSRK---------------------------- ----------------------------------- >XP_018106279.1 bone morphogenetic protein 1 L homeolog isoform X1 [Xenopus laevis] ------------------------------------------------------------ --------------------------------------MPWLGS---------------- ----PP----LL----------------------LWA-------------LLAG------ ------------MLHLGQ-------------------GQEFL------------------ ------------DYSYDLEE--------------------------VVEESIDYKDP--- ----------------------C-------KA-------AAFW-GDIALDEED------- ------------LANF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------KVARIVD-----------------------LTKHTISTVSGAAS------ -----------------------------------------------NSSRPQR------ ------------------------GRRTRKE-RRR--------SRERRAATSRPERVWPD GVIPYVISGNFSGSQRAIFRQAMRHWEKHTCVTFLERTD----EDSYIIFTYRPCGCCSY VGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDDHVSIIRENIQPGQEYN FLKM-EPEEVESIGETYDFDSIMHYARNTFSRGIFLDTILPKYDVN---GVRPPIGQRTR LSSGDIAQAKKLYRCPACGETLQDSQGNFSSPGFPNGY---SAYMHCVWRLSVTPGEKII LNFTSLDLYRS---RLC---WYDYIEVRDGFWKKAPLRGRFCG-DKIPEP-----IISTE SRLWIEFRSS--SNWVG--KGFQAVYEALCGGDVK-KDS--GHIQSPNYPDDYRPNKACV WKLSVS-EGFHVGISFQSFEIERHDSCAYDYLEIRDGSSESSPLIGR-----FCGYDKPD DIKSSTNQLWVKFVSDGSINKAGFSLNYFKEVDECSRPNNGGCEQRCVNTLGSYKCACDP GYELGPDKKSC--------EAACGGFLTKLNGSITSP-GWPKEYPPNKNCVWQLVAPTQY RISLKFDQFETEGNDV----CKYDFVEVRSGLTSDS-KLHGKFCGTELPAVI-TSQYNNM RIEFKSDNTVSKKGFQANFFS--DK--DECSQDNG----GCQHECTNTLGSYICQCRSGF TLHENKH---DCKEAG-CDHKVTGSTGTISSPNWPDKYPSKKICTWQITATPGHRAKLTV SEVDLESHQECLYDHVEVYSGCDAQSPALNRFCGSKIPDPIISPGNTMFLKFMSDNSVQK RGFLGELSSVCGGTLHAEVRTQDLYSHAKFGDDTHPSGTECLWHIVSEA-GYGVELVFQS FELEEEPDCGYDYMELYDGPD----EGAPRL-GRYCGSGPPE---EVYSAGDALTIKFHA DDTINKKGFHVRYTSTKFQDT------LHARK---------------------------- ----------------------------------- >XP_040530575.1 tolloid-like protein 2 isoform X1 [Gallus gallus] ------------------------------------------------------------ --------------------------------------MGRGATPL-------------- ----RR----LL----------------------LSL-------------LLLP------ --------------GPGL------------------------------------------ ----------------AAGEPE------------------------TAEEQMEYRDP--- ----------------------C-------KA-------AAFW-GDIALDEDD------- ------------LKLF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QIDRTVD-----------------------LTKHSAGNARHTSG------ --------GLG-EQSFEPS--------------------------ENTTSTDSKKAVKTD GRQNTTLVRSLKKKE--------YKDESGMDARSS--------PRVRRATTSRAERIWPG GVIPYVIGGNFTGTQRAIFKQAMRHWEKHTCVTFVERTD----EESFIVFTYRTCGCCSY VGRRGGGPQAISIGKNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQQGQEYN FLKM-EAGEVNSLGETYDFDSIMHYARNTFSRGVFLDTILPRRDDN---GVRPTIGQRVR LSQGDIAQARKLYKCPACGETLQDSTGNFSAPGFPSGY---PSYSHCVWRISVTPGEKIM LNFTSMDLFKS---RLC---WYDYVEVRDGYWRKAPLLGRFCG-DKIPEP-----VISTD SRLWIEFRSS--SNILG--KGFFVVYEAICGGEVR-KDA--GQIQSPNYPDDYRPSKECI WKITVS-EGFHIGISFQAFEIEWHDACSYDYLEIRDGLTENSPLIGQ-----FCGYEKPE DIKSSSNKIWMKFTSDATISKAGFAANFFKEMDECSQPDNGGCEQHCENTLGSYKCTCEP GYELTADKKSC--------EAACGGFITKLNGTITSP-GWPKEYPTNKNCVWQVVAPAQY RISLQFEVFDLEGNDV----CKYDYVEVRSGLATDS-KLHGKFCGSEKPEVI-TSYSNNI RLEFKSDNTVSKKGFKVHFFS--DK--DECSKDNG----GCQHECINTFGSYVCQCRNGF KLHENNH---DCKEAG-CEHKLSSAEGMMSSPNWPDKYPSRKECTWNISATPGHRVKVTF HEFEIEQHQECAYDHLEMYDGPNSKSPILGRFCGSKKPDPVVASTNKMFLRFYSDASVQR KGFQAKHSTVCGGLLKAEVQTKELYSHAQFGDNNYPGQANCDWVIVAED-GYGVELMFQT FEIEEEADCGYDYMEIYDGYD----STAPRL-GRFCGSGPLE---EIYSAGDSIMIRFHT DDTINKKGFHAQYISTKFQDA------LHMRK---------------------------- ----------------------------------- >XP_031410433.1 tolloid-like protein 2 [Meleagris gallopavo] ------------------------------------------------------------ --------------------------------------MAKHPEGE-------------- ----------VF------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------------------CF------SP-------AAFW-GDIALDEDD------- ------------LKLF-------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ----------QIDRTVD-----------------------LTKHSAGNARHTSG------ --------GLG-EQSFEPS--------------------------ENTTSTDSKRAVKTD GKQNTTLVRSLKKKE--------RKDESGMDARSS--------PRVRRATTSRAERIWPG GVIPYVIGGNFTGTQRAIFKQAMRHWEKHTCVTFVERTD----EESFIVFTYRTCGCCSY VGRRGGGPQAISIGKNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQQGQEYN FLKM-EAGEVNSLGETYDFDSIMHYARNTFSRGVFLDTILPRRDDN---GVRPTIGQRVR LSQGDIAQARKLYKCPACGETLQDSTGNFSAPGFPSGY---PSYSHCVWRISVTPGEKIM LNFTSMDLFKS---RLC---WYDYVEVRDGYWRKAPLLGRFCG-DKIPEP-----VISTD SRLWIEFRSS--SNILG--KGFFVVYEAICGGEIR-KDA--GQIQSPNYPDDYRPSKECI WKITVS-EGYHIGISFQAFEIEWHDACSYDYLEIRDGLTENSPLIGQ-----FCGYEKPE DIKSSSNKIWMKFASDATISKAGFAANFFKEMDECSQPDNGGCEQHCENTLGSYKCTCEP GYELTADKKSC--------EAACGGFITKLNGTITSP-GWPKEYPTNKNCIWQVVAPAQY RISLQFEVFDLEGNDV----CKYDFVEVRSGLATDS-KLHGKFCGSEKPEVI-TSYGNNM RLEFKSDNTVSKKGFKIHFFS--DK--DECSKDNG----GCQHECINTFGSYVCQCRNGF KLHENNH---DCKEAG-CEHKLSSAEGMMSSPNWPDKYPSRKECTWNISATSGHRVKVTF NEFEIEQHQECAYDHLEMYDGPNSKSPILGRFCGSKKPDPVVASTNKMFLRFYSDASVQR KGFQAKHSTVCGGLLKAEVQTKELYSHAQFGDNNYPGQANCDWVIVAED-GYGVELIFQT FEIEEEADCGYDYMEIYDGYD----STAPRL-GRFCGSGPLE---EIYSAGDSIMIRFHT DDTINKKGFHARYISTKFQDA------LHMRK---------------------------- -----------------------------------
BMGE Cleaned alignment of selected proteins >sp|P13497|BMP1_HUMAN Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 PE=1 SV=2 MPGVARPLDLADYTYDLAEEDDSEPLNYKDPGDIALDEEDQVQQAVDLRRHTARKSSIKAAGACGRWSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDTLHSRK >sp|P13497-2|BMP1_HUMAN Isoform BMP1-1 of Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 MPGVARPLDLADYTYDLAEEDDSEPLNYKDPGDIALDEEDQVQQAVDLRRHTARKSSIKAAGACGRWSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSRPALQPPRGRPHQ-------------------------------------------------------------------------------------------------------------------------LKF----RVQKR-------------------------------------------------------------------------------RTPQ---------------------------------------------------- >sp|P13497-3|BMP1_HUMAN Isoform BMP1-4 of Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 MPGVARPLDLADYTYDLAEEDDSEPLNYKDPGDIALDEEDQVQQAVDLRRHTARKSSIKAAGACGRWSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGVLHSSLLLSCGSRNGASFPCSLESSTHQA--LCWTGLFL------------RPS----------------------------------------------------------------------------------------------------PFP------RL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------P---------------LAAPR------------------------TLRAGV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- >sp|P13497-4|BMP1_HUMAN Isoform BMP1-5 of Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 MPGVARPLDLADYTYDLAEEDDSEPLNYKDPGDIALDEEDQVQQAVDLRRHTARKSSIKAAGACGRWSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEGC-------YDLQVGKPLW------DRHC---------FRLS------------------------------THG-------PEML----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GTALRG----------------------------------------------------------------------------------------------------------------------- >sp|P13497-5|BMP1_HUMAN Isoform BMP1-6 of Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 MPGVARPLDLADYTYDLAEEDDSEPLNYKDPGDIALDEEDQVQQAVDLRRHTARKSSIKAAGACGRWSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FGLLGHP----------------------------------------------PRR-------P------------------------------------------- >sp|P13497-6|BMP1_HUMAN Isoform BMP1-7 of Bone morphogenetic protein 1 OS=Homo sapiens OX=9606 GN=BMP1 MPGVARPLDLADYTYDLAEEDDSEPLNYKDPGDIALDEEDQVQQAVDLRRHTARKSSIKAAGACGRWSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDRHSHLSGLCPHALVDTVPAPPSALHGDTHAHTHTHHCPIAQETCRGPPLGASRLSPQGPG--------------------HLTLAPQE----------------------------------------GS--YLDFWD-----------TH--------RGDPK--------------------------------------------------------------PRRRRKS---------------LKTF----SLTPATFRGIWAL----------- >tr|F1REM3|F1REM3_DANRE Metalloendopeptidase OS=Danio rerio OX=7955 GN=bmp1a PE=4 SV=2 MELAARDLDAIEPGYYVETSSPSDLIDYKDPGDIALDEEDTVDRIVNLADRTVTILNHTNT------HRRRRAATSRPERVWPEGVIPYVISGNFSGSQRAIFRQAMRHWEKHTCVTFIERTTEESYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDEHVSIIRDNIQPGQEYNFLKMEPGEVDSLGEVYDFDSIMHYARNTFSRGIFLDTILPRYDVNGVRPPIGQRTRLSKGDIAQARKLYKCPRCGDSLQESSGNFSSPGYPNGYSAYMHCIWRISVTPGEKIILNFTSMDLYRSWYDHVEIRDGYWRKAPLKGRFCGDKLPDPIISTDSRLWIEFRSSSNWVGKGFSAVYEAICGGEVKGQIQSPNYPDDYRPNKVCVWKITVAQGYHVGLTFQSFEIERHDNCAYDYLEVRDGNSESSPLLGRFCGYDKPDDIKSSSNQLWMKFVSDGSVNKAGFAANFFKEMDECSRPDNGRCEQRCVNTLGSYKCACDPGYELAADKRSCEAACGGFITKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRITLLFDVFETEGNDVCKYDFVEVRSGLSADSRLHGKFCGAEKPEAITSQYNNMRIEFKSDNTVSKKGFKAQFFSDECSKENGGCQHECVNTFGSYSCQCRSGFVLHENKHDCKEAGCDHVVNSVSGTITSPNWPDKYPSKKACTWALSTTPGHRIKIAFNEIDMEPHLECAYDHIEIYDGRDSKAQSLGRYCGTKKPQPIISTGNKMFIRFFSDNSVQKKGFEASHTAECGGRLKAEVKTKDLYSHAQFGDNNYPGASDCQWVITAEKGYGVELIFQTFEIEEEADCGYDYMELFDGADKSPRLGRYCGSGPPEEIYSAGDSIVIKFHSDDTINKKGFHVRYTSTKFQDTLHSRK >NP_033885.2 bone morphogenetic protein 1 precursor [Mus musculus] MPGVARPLDLADYTYDLGEEDAPELLNYKDPGDIALDEEDQVQQAAVLRQQTARRPSIKAAESRGRWPRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPSIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSNLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCEHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFVEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGFQASHSTECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYIELFDGYDTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTISKKGFHLRYTSTKFQDTLHSRK >NP_112613.1 bone morphogenetic protein 1 precursor [Rattus norvegicus] MPGVARPLDLADYTYDLGEEDAPELLNYKDPGDIALDEEDRVQQAAVLRQQTAQRSSIKAAGSRGRWPRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPSIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSNLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCEHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFVEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGFQASHSTECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTISKKGFHLRYTSTKFQDTLHSRK >XP_016814692.1 bone morphogenetic protein 1 isoform X1 [Pan troglodytes] MPGVARPLDLADYTYDLAEEDDSEPLNYKDPGDIALDEEDQVQQAADLRQHTARKSSIKAAGACGRWSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDTLHSRK >XP_024852018.1 bone morphogenetic protein 1 isoform X1 [Bos taurus] MPGVARPLDLADYTYDLGEEDDAEPLNYKDPGDIALDEEDQVQQAADLRQRATRRSSIKAARSRGRWSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKGHIQSPNYPDDYRPSKVCVWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSSSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVYDGRDSKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDTLHSRK >XP_020927995.1 LOW QUALITY PROTEIN: bone morphogenetic protein 1 [Sus scrofa] MPGVARPLDLADYTYDLGEEDDAEPLNYKDPGDIALDEEDQVQQAADLRQRTTRKSSIKAARSHGKWSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFLEMDIESQPECAYDHLEVYDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQAAHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDTLHSRK >XP_002818918.1 bone morphogenetic protein 1 isoform X1 [Pongo abelii] MPGVARPLDLADYTYDLAEEDDSEPLNYKDPGDIALDEEDQVQQAADLRQHTARKSSIKAAGACGRWSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDTLHSRK >XP_038291401.1 bone morphogenetic protein 1 isoform X1 [Canis lupus familiaris] MPGVARPLDLADYTYDLGEEDDSEPVNYKDPGDIALDEEDQVQQVADLRQRTTHRSSIKTARSRGRWSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMELQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSETSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVYDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDTLHSRK >XP_003823651.1 bone morphogenetic protein 1 isoform X1 [Pan paniscus] MPGVARPLDLADYTYDLAEEDDSEPLNYKDPGDIALDEEDQVQQAADLRQHTARKSSIKAAGACGRWSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDTLHSRK >XP_023108277.1 bone morphogenetic protein 1 isoform X2 [Felis catus] MPGVARPLDLADYTYDLGEEEDSEPVNYKDPGDIALDEEDQVQQAEDLRQRATHRSSIKTTRNRGRWSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMELQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFVEMDIESQPECAYDHLEVYDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRFTSTKFQDTLHSKK >XP_014948597.2 bone morphogenetic protein 1 isoform X3 [Ovis aries] MPGVARPLDLADYTYDLGEEDDAEPLNYKDPGDIALDEEDQVQQAADLRQRATRRSSIKAARSRGRWSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKGHIQSPNYPDDYRPSKVCVWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSSSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVYDGRDAKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEESDCGYDYMELFDGYDTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDTLHSRK >XP_030869708.1 bone morphogenetic protein 1 isoform X1 [Gorilla gorilla gorilla] MPGVARPLDLADYTYDLAEEDDSEPLNYKDPGDIALDEEDQVQQAADLRQHTARKSSIKAAGACGRRSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSLDLYRSWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDECSKDNGGCQQDCINTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLRFYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDTLHSRK >XP_021154607.1 bone morphogenetic protein 1 [Columba livia] M------------------------------------------------------------------QESRRAATSRPERVWPDGVIPYVISGNFSGSQRAIFRQAMRHWEKHTCVTFLERNDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDDHVSIIRENIQPGQEYNFLKMEPEEVESLGETYDFDSIMHYARNTFSRGIFLDTILPKYDVNGVRPAIGQRTRLSKGDIAQARKLYRCPACGETLQDSQGNFSSPEFPNGYSAHMHCVWRISVTPGEKIILNFTTLDLYRSWYDYVEVRDGFWRKATLRGNQTGSSQPARLLPNRGMLGVQA------AGQGGFSSLTAICGGDVKGHIQSPNYPDDYRPSKVCIWKITVSEGFHVGLTFQSFEIERHDSCAYDYLEIRDGSSESSSLIGRYCGYDKPDDIKSTSNKLWMKFVSDGSINKAGFAVNFFKEVDECSRPNNGGCEQRCINTLGSYKCACDPGYELASDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGAEKPDVITSQYNNMRIEFKSDNTVSKKGFKAHFFSDECSKNNGGCQHECLNSFGSYECQCRSGFVLHDNKHDCKEGG------------SAP----------------------------------------------------------RFCGAKEPEPLISSSNKMFLKFVSDNSVQKKGFEATHATVCGGQVHAEVKTKDLYSHAQFGDNNYPGGSDCEWVIMAEEGYGVELIFQTFEIEEEADCGYDYMELFDGYDTAPRLGRFCGSGPPEEIYSAGDSVMIRFHSDDTINKKGFHLRYTSTKFQDTLHTKK >XP_017907774.1 PREDICTED: bone morphogenetic protein 1 isoform X1 [Capra hircus] MPGVARPLDLADYTYDLGEEDDAEPLNYKDPGDIALDEEDQVQQAADLRQRATRRSSIKAARSRGRWSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKGHIQSPNYPDDYRPSKVCVWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSSSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVYDGRDAKAPVLGRFCGSKKPEPVLATSNRMFLRFYSDNSVQRKGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEESDCGYDYMELFDGYDTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDTLHSRK >XP_025066133.1 bone morphogenetic protein 1 [Alligator sinensis] MAGDPEGYDTHDDIETASDLTEAASLGGKGAGDIALDEEDQADRITDLTRHTMLRVAT---RKRHGWSRSRRAATSRPERVWPDGVIPYVISGNFSGTQRAIFRQAMRHWEKFTCVTFLERTEEDSYIIFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDDHVAIIKENIQLGQEYNFLKMEPEEVESLGETYDFDSIMHYARNTFSRGIFLDTILPKYEVQGLRPSIGQRTRLSKGDISQARKLYRCPDCGETLQESQGNFSSPDFPNGYAAHKHCVWRISVTPGEKIILNFTTLDIYRSWYDYVEVRDGFWRKATLRGRFCGNKLPEPIISTDSRLWIEFRSSSNWVGKGFFAAYEAICGGEVKGHIQSPNYPDDYRPSKVCIWKITVSPGFHVGIIFQSFEIERHDNCAYDYLEIRDGPSESSKELGRYCGYDKPDDIKTTSNKVWMKFVSDGSINKAGFSVTFFKEADECSRSDNGGCEQRCVNTLGSYKCACDPGYELAADKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLKFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGAEKPDVITSQYNNMRIEFKSDNTVSKKGFKAHFFSDECSKDNGGCQHECLNTFGTYMCQCRSGFVLHDNKHDCKEAGCDHKVTSISGTITSPNWPDKYPTKKECTWALTTTAGHRIQLTFTELDIESHQECTYDHLEAYNGKDAKAPVLGRFCGAKKPEPIMSTSNKMFLKFFSDNSVQRKGFQASHTTVCGGQMRAEVKTKDLYSHAQFGDNNYPSGTDCEWVIMAEEGYGVELIFQTFEIEEEADCGYDYMELFDGYDSAPRLGRYCGSGPPEVVYSAGDSVMIKFHSDDTINKKGFHLRYTSTKFQDTLHTRK >XP_019347110.1 PREDICTED: bone morphogenetic protein 1 [Alligator mississippiensis] MAGGRAALDVADYP-DYAE-PEPEPLDYKDPGDIALDEEDQADRITDLTRHTTLRVAT---RKRHGWSRSRRAATSRPERVWPDGVIPYVISGNFSGNQRAIFRQAMRHWEKFTCVTFLERTEEDSYIIFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDDHVAIIKENIQLGQEYNFLKMEPEEVESLGETYDFDSIMHYARNTFSRGIFLDTILPKYEVQGLRPSIGQRTRLSKGDISQARKLYRCPDCGETLQESQGNFSSPDFPNGYAAHKHCVWRISVTPGEKIILNFTTLDIYRSWYDYVEVRDGFWRKATLRGRFCGNKLPEPIISTDSRLWIEFRSSSNWVGKGFFAAYEAICGGEVKGHIQSPNYPDDYRPSKVCIWKITVSPGFHVGIIFQSFEIERHDNCAYDYLEIRDGPSESSKELGRYCGYDKPDDIKTTSNKVWMKFVSDGSINKAGFSVTFFKEADECSRSDNGGCEQRCVNTLGSYKCACDPGYELAADKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLKFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGAEKPDVITSQYNNMRIEFKSDNTVSKKGFKAHFFSDECSKDNGGCQHECLNTFGTYMCQCRSGFVLHDNKHDCKEAGCDHKVTSISGTITSPNWPDKYPTKKECTWALTTTAGHRIQLTFTELDIESHQECTYDHLEAYNGKDAKAPILGRFCGAKKPEPILSTSNKMFLKFFSDNSVQRKGFQASHTTVCGGQMRAEVKTKDLYSHAQFGDNNYPSGTDCEWVIMAEEGYGVELIFQTFEIEEEADCGYDYMELFDGYDSAPRLGRYCGSGPPEVVYSAGDSVMIKFHSDDTINKKGFHLRYTSTKFQDTLHTRK >XP_020755633.1 bone morphogenetic protein 1 [Odocoileus virginianus texanus] APSPAPPLDLADYTYDLGEEDDAEPLNYKDPGDIALDEEDQVQQAADLRQHATRRSSIKAARSHGRWSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKGHIQSPNYPDDYRPSKVCVWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSSSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVYDGRDSKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDTLHSRK >XP_040202086.1 bone morphogenetic protein 1 isoform X1 [Rana temporaria] MPWTGRPLGEEDYTDLYTELESEEHIDYKDPGDIALDEEDKIDRIVDLRNRTISTVSRPARGRRARTSRGRRAATSRPERVWPHGIIPYVVSGNFTGSQKAIFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDHHVTIIRDNIQPGQEYNFLKMEQEEVESLGETYDFDSIMHYAKNTFSRGIFLDTILPKYEVNGVKPSIGQRTRLSVGDITQARKLYQCTACGDTLQDSQGNFSSPGYPNGYSAYVHCVWRLSVTPGEKIMLNFTSLDVYRSWYDYIEVRDGHWKKAPLIGRYCGEKIPEPIISSDSRLWIEFRSSSNYVGKGFHAVYEALCGGEMKGHIQSPNYPDDYRPNKSCVWKLRVSEGFNIGVTFQSFEIERHDSCAYDYLEIRDGNTEFSPLIGRFCGYDKPDDLKSSSNQLWVKFVSDGSINKAGFSIHFFKEVDECSRPHKGGCEQRCVNTLGSYKCACEPGYELAPDKKSCEAACGGFLTKLNGSLTSPGWPKEYPPNKNCIWQLVAPTQFRISLKFDKFETEGNDVCKYDYVEIRSGLTADAKLLGTFCGAELPPVITSQYNNMRIEFKSDNTVSKKGFRATYYSDECSRDNGGCQHECTNTQGSYTCHCRSGFTLHENKHDCKEAGCNHKVLASNQNISSPNWPDSYPSKKECTWQVTSTAGHRVKLIVKEVDLESHQECIYDHVEVYSGTDAQSPVLKRLCGSKVPEPIIAPGSSMFVKFVSDNSVQKKGFLAELTTECGGTLQAEVRTKDLYSHAKFGDDIHPSATECIWHIVSEGKYGVELVFQSFELEEEQDCGYDYIELYDGPTGAPRMGRYCGSGPPEEVYSTGESLTVRFHSDDSINKKGFHIRYTSTKFQDTLNARK >XP_039272807.1 bone morphogenetic protein 1-like [Styela clava] MKFLKTSQE--QTTIWVDQPEESEDKILKDPGDIALDEVDTVQEFMDINSQKSKKHSVREAKRRGRYKRMRRAATARPERIWPAGVIPYVISANFTGSQRAMFKQAMRHWEAQTCITFIERTDEEAFIKFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHIEIIYKNIQPGQEYNFEKMDSSEINSLGETYDYYSIMHYARNTFSKGMFLDTIKPRVDANGARPTIGQRTRLSDGDVAQAKKLYQCNTCGYTLQDTSGNITSPNYPQYYPAESHCIWRISVTPGEKIVLDITSLDIYESYYDFLEIRDGHWYRSPKIGQYCGRSLPATITSTDSRLWLQFRTSTYYQGRGFTLKYEAVCGGTIRGQIQSPNYPDDYRPSKECIWKVVVDEGFRVGLSFQAFEVERHDTCSYDYLEVRDGPTADSDLIGRFCGYDKPEDVKSTSNTLWIKFVSDGSVNKAGFAASFFKEIDECEDKRKSGCQQGCVNTLGSYKCVCDPGYELAADGRTCEAACGGSVTNLDGYITSPNWPNEYPTNKKCVWQIVAPPQHKISIQFEKFELEGNEVCKYDYVEIRSGLSDDAKFHGRFCGLELPPVIRSTINEMSLAFKSDDTVSKRGFKIKFFSDECAISNGGCEHECVNTIGSYSCTCRNGYVLHTNKRGCKEAGCKHDIKTAVGEITSPNWPNKYPSRKECTWLIRTTPGHRVKVVFHEFELETQPECAYDHLELYDGSDSDQTVLGRYCGSKKPGTIVATTSIMFIKFFSDASVQKRGFSATHQTVCGGNLNASTRSKDLFSHPQYGDNNYISGQECDWIITADTGLVVRLTFTAFEVEEETDCSYDFVEVYDGEDSATRFGRYCGSKALSTIMSTSGSLLLRFHSDDTINKKGFHARYSSSSYEDISESSS >XP_038060664.1 bone morphogenetic protein 1 homolog isoform X1 [Patiria miniata] MGPVTLEGD--PHVYW----RSTVTEEFADPGDIALTEEQKLQEYKQIRKKTNKQHEEKQLEEEETEHRVARAVTSRPERKWPYGVIPYVIDGNFTGSQRAMFKQAMRHWENYTCITFVERSPHRNYIVFTYRSCGCCSFVGMRAEGAQAISIGKNCDKFGVVVHELGHVVGFWHEHTRPDRDDHVTIVKENILPGQEYNFNKLLPEEVDSLGQPYDFASIMHYARNTFSRGIWLDTVIPQRDPDRAEIEIGQRKQLSEGDITQANLLYKCPACGRTLQETTGNFSSPGWPEQFNSRESCVWRISVTPGETIVLTFEDFELVGSWYHHVEVRDGHWRFSNVLGRFCGSNIPPVIVSTDSRLWIELKSSGNAVSRGFAAHYEAVCGGNISGMLQSPNYPDDYRPDKSCVWYLTMPEGFQVGLNFQSFEVERHDNCIYDYVEVRDGHEDDSPLIGKYCGYLMPEDIKSSSNKLRVKFVSDGTVNKGGFSADFFKEDDECSK-NNGGCEQICVNTIGSYRCECEPGFELKADGESCEVACGGFLTSLQGNITSPSYPDLYPRDKNCVWHLVAPSLYRISLQFLSFELEGNDVCKYDYVEVRSGLTEVGDLHGKFCGDDIPDTITSRYNNMRIEFKSDSTVSRPGFFAMFFADECEKNNGDCQHVCVNTLGSYTCSCRNGFTLHENGHDCKESGCRHDIRSSHGEITSPNYPDNYPKRKECTWHIVATPGHKVELVFNDFDLEHHLECAYDHVVIYDGDSSEGHLLGRFCGTRIPDPVLANTNQMYITFFSDASVSRRGFFATHSTICGGVLQADYVSQKLYSHADYGDNNYGSQEDCEWTILAPQGYSVRLMFRSFDIEHETECDYDSLEVLDGDSDSERIGRFCGHKIPDDIISQGENLRLIFRSDDTISKKGFYAEYQIS---------- >XP_030834881.1 bone morphogenetic protein 1 homolog isoform X1 [Strongylocentrotus purpuratus] MDLLYY-----SLTTFIGETTRALSDDVSSPGDIALTEDDNREQY----------------KKRTIEVRHVRAVTARPERRWTDAVIPYEIDGNFTGSQRAMFKQAMRHWENYTCITFVERNPHDNHIVFTYQACGCCSFVGRKGDGAQAVSVGKNCDKFGVVVHELGHVVGFWHEHTRPDRNEFVGIVHQNIVPGQEYNFRVLDAAEVDSLGETYDFASIMHYARNTFSRGIWLDTILPRKDPEGIRPEIGQRKHLSEGDIIQANLLYKCPSCGRTLLESTGNFSSPEWPGQYDGDQTCVWRISVTPGETISLQFTGFELVGSWYNYLEVRDGHWRHSPLLGRFCGASLPDPILSSDSRLWIELKSSAHRYSRGFAANYEAICGGHIEGTLQSPNYPDDYHPSKECVWLITMPANYTVGLSFQSFEIERHETCIYDYVEVRDGHEDTSPLIGRYCGYFIPDDIKSTGNKMMVTFVSDGSVNKGGFSADFFKEKDECAQPDQGGCMDVCVNTIGSYRCDCRPGYELSSDGRRCEVACGGLFTGLRGNISSPSYPEPYPRDKNCVWQIVAPSNYRISLQFITFDLEGNEVCKYDYVDVRSGLNEEGTLHGKFCGNEIPETITSRFNNLRIDFRSDNTVAKEGFFANFFADECEEGNGGCQHICTNTLGSYTCSCRNGFTVHENLHGCKESGCRREIQSTTGIITSPNYPDNYPKRKECTWHISANPGHKIVLSFDDFDLEQHQECTYDRVQVFDGDSDEGQVLGRYCGATIPDAVVSSSNHMFIRFYSDASVSRSGFSATHSTQCGGRLEAELSAQRLYSHADYGDQNYENQESCEWTIVSPDDHFIHLWFRSFDIEHETECNYDQVMILDGDNAAESFGKFCGHRAPDDIVSSGDSLMITFSSDDTINKKGFLAIFKLTDGELLEGAGE >CAE1240683.1 tok [Sepia pharaonis] MLSSGSEQD--STNISYKQPRKTSNDLYMDPNDIALTDDDNIEVQVDVSKRRPRKKNKGSHKPVSEAWRTRRAATARQDRLWEYGVIPYQIEANFSGPHKALFRLAMRHWENHTCITFVERTPHEDYIVFTERPCGCCSYVGKRGNGAQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDDHVQIIYKNIMPGQEYNFNKLTPADVNSLGEEYDYGSIMHYARNTFARATFVDTILPKRKY-GTR-DIGQRIKLSPGDIRQANRLYRCASCGRTLQAATGEFSHKPNQQRTEEREVCEWRISATHGEKIVLNITSLDVPESVTDYLEVRDGYYERSTKLGKFCGKTVPGVLQSTDSRMWLRFVSTQK-KGEGFVAKYEAICGGVINGTLTSPNSPDDYRANQECVWRITVPKAYLVGLMFQSFEIENHDNCVYDYLEIRDGPDETSPSLGKFCGYKVPEDIKSSGNQLYVKFVSDGSVQKAGFSATFTEEYNECLT-DYHGCDHICVNTLGSYKCMCEIGYELHSDGRKCEDACGGYISIENGTFQSPSFPDLYPTNKYCVWQIVAPKQHRITLNFSYFDLEGNNQCEYDSVRVSNGLNSDTKAIGIFCGSTLPDSITSSENSLRIEFSSDNSVQKTGFNATFFTDECALKNGGCQQICRNTIGSYQCACQNGFTLHENKHDCKEGGCKHQIKTPSGNINSPKWPDFYPSRKDCVWTFTVTDGHRVKLEFEEFELEPHQECTYDHIEIFDGTSTNSRSLGRFCGNKIPPPTYSSGNTMFMIFYSDASVQRKGFSAMHSTVCGGHLLAKTEPKFIYSHAKYGDQNYDNAADCDWIIEAEDDQRIYVEFKAFEIEDESECMYDYVKLYDGKSTGSAIGKYCGSNKPPPVTSSGRILTIRFVTDDTVNWKGFSLTYRLAEDQSTGETQE >XP_006567027.2 tolloid-like protein 1 isoform X2 [Apis mellifera] MVASQEESTTPQTASNATKSRTSEELNVAFPQMRNLNAENTIQPESSTSKQRHRRHHRRRTGARKRESRARRAATARKERVWDHGVIPYEIDGNFSGAHKALFKQAMRHWENFTCVKFVERVPHPNYILFTERPCGCCSFVGKRGNGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVQIIRDNIMSGQEYNFNKLTEDEVNSLGLPYDYDSIMHYAKNTFSRGTYLDTILPMEVHGKKRPEIGQRLRLSEGDIAQTNLLYKCYKCGRTFQENSGSFGSPTHPNSSSEGERCEWRITATHGERIVLNITSLDIFKSRSDYLEIRDGYWYKSNVLGRYCGGKIHEPVVSTGSRMLVTYVTSNYQSGRGFTASYEAVCGGEIEGHLESPNYPDGYQSSKECVWKLSVPQNFQVALKFQSFEIENHDNCVYDYVEVRDGHNADSPLIGVYCGYKIPPDIKSTGNKLLVKFVSDGSVQKAGFSATFMKEFDECVL-IDHGCEHNCINTLGGFECSCKPGYELHSDGKHCEDACGGVFEDSNGTITSPSFPVTYPGNKDCVWEIIAPPQYRITLNFTHFDLEGTNACEYDSVEVSSKLGDDIRKHGVFCGSRLPSLITSEGNSMRVTFTSDNSIQKTGFAAVFFTDECATNNGGCQHECRNTIGSYQCSCHNGFTLHENGHDCKEGGCKYEIAAPMGTITSPNYPDYYPGLKDCVWHFVTKPGHRIKLVFKVFEMESHQECNYDHIAIYDGDSPDSHVLGKFCGTKEPHPILATGNQMYMVFKSDASVQRKGFFATHSTACGGHLVATNEIRHLYSHARYGVHNYDHRTDCDWAIEAPPGKNVHLTFVTFQLESESDCNYDFVEVYSGLDSGLLYGRFCGNSNTTDFISINEALLVRFRTDDTISNKGFMALFVAVDRQDSSEDED >NP_001287510.1 tolkin, isoform C [Drosophila melanogaster] LGVSWTDVDEDRSKYTIEQLPKVSGDIDMDPGDIALPEGDRLREELSQKQAQHRQHHQSHHTSKDEEHRVARAVTAKKERIWDYGVIPYEIDGNFSGIHKALFKLAMRHWENSTCIKFVERDPHPNYIVFTVRSCGCCSFVGKRGNGPQAISIGRNCDKFGIVVHELGHVVGFWHEHTRPDREKHVVIEHNNIMKGQDYNFNMLSPDEVDSLGMAYDYDSIMHYARNTFSKGTYLDTILPIEMKGRKRPEIGQRLRLSQGDIAQANLLYKCPKCGRTFQESSGIFASPSHYTAGNETEHCEWRITATYGERVELKLENMNIFKSETDYLEIRDGYFEKSPLIGRFCGKVDKEVIRTESSRMLLTYVNTHRIEGRGFKAEFDVVCGGELSGRLESPNYPLDYLPNKECVWKITVPESYQVALKFQSFEVENHDSCVYDYVEVRDGPGQDAPLIGVFCGYKPPPNMKSSGNSMYVKFVSDTSVQKAGFSAVFMKEVDECET-QNHGCEHECINTLGGYECSCRIGFELHSDKKHCEDACGGVIEYPNGTITSPSFPEMYPLLKECIWEIVAPPKHRISLNFTHFDLEGTAHCGYDSVTVYSKLGENRKRIGTFCGSSIPPTATSESNALRLEFHSDKSIQRSGFAAVFFTDECAVNNGGCQHECRNTIGSYICMCHNGYSMHENGHDCKEGECKYEISAPFGTIFSPNYPDSYPPNADCVWHFITTPGHRIKLIFNEFDVESHQECTYDNVAVYDGESESSSVLGRFCGDKIPFPISSTSNQMYMVLKTDKNKQKNGFTASHSTACGGYLRATSQVQQFYSHARFGNQDYDDGMDCEWTIAAPDNSYVQLIFLTFDIESSENCTFDYVQVFSDIDYGPMYGQYCGNVLPQDINSMTHSLLVRFKTDGSVPMKGFSASYVAVPNSGEYDHSD >XP_031559878.1 tolloid-like protein 1 [Actinia tenebrosa] MAWTA---------------VNGDNEDY-DPGDIATN------------------------------MRTRRAATADRNRFWKDGMIPYDIEIDYTGEQKATILRAMRHWENFTCLSFIEKSDDDDYIYFHNGRCGCCSFVGRKGNGRQGISIGKNCDKFGIVVHEIGHVVGFWHEHTRPDRQEYVTIINENIKKGEEHNFQKLTNRDIDSRNEDYDYGSIMHYGKYTFSTSKNHVTILPKRNPFRMVPIIGQREKLSNGDVRQTHKMYRCPECGRTLQEPKGSFTSPGYPKPYSQNKHCEWRISVTPGERIVLNFTKFNLRKAKHDFLEIRDGHGRKSNLIGRYCGKKFPPTIWSTGSRLWIKFKSGSSEIKFGFAAKYETRCGGPIRGTIQSPNYPSWYPSKKECVWTIELPKNLNVGVRFVAFDIEAHEQCDYDYLQLFNGPDTSSPSLGKFCGKTIPSDIKSNSSYLTLKFNSDTSINKPGFYITFFSERNECKV-NNGGCSQICRNTLGHYECECYPGFELHSNGKDCEAACGGILSDRNGTIMSPSYPANYPKNKGCTWQITGLKGQRVSLKFKEFKLEGSANCRYDYVEIRD---ENNKVLKKLCGSSIPKTITSPSNVMFVDFRSDHTQSRKGFLAMYYSDECQKRKGGCQHICVNTIGSYRCACKPGFTLHSNKHSCKEASCSATLTTQTGLIMSPNYPGVYQHKKDCTWKIVVKPGSHVELNFRFLQIEEANDCRYDYVEIFSGTGGQAESIGRVCGNSLPSPVLSKAHKLMIKFHSDALIAKRGFKARYNAICGAKLNAINTARTFYSHPAYGDDDYSPSVKCRWTISTRNG-FVKLRFKEFEVEKEKYCSYDGVTIRDGSNTSPLLGKICGNSAKNEFLSTSNKMFIEFVSDLTTQKKGFIAEYVRVKRKGRNRSKE >NP_001360030.1 Zinc metalloproteinase nas-39 [Caenorhabditis elegans] MRFSAN-------------------VEFVLPGDV---------------------------RFRRYYGRVSRAATAKKERIWPEGIIPFVIASNFSGEHQHLFLRAMRHWENFTCVSFVPRQPHKHYITFTVDKCGCCSYVGRRGEGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDMYVDIFYKSIQTGQDYNFEKSKPEEVDSLGEPYDFSSIMHYARDTFSRGAFYDTILPKPNS-GFRLEIGQRVQLSEGDIRQTKKLYKCAECGGTLMQESGNLAI-------QHAGVCTWHIISPQGHTIFLNITGSTLSPPEDNVITVRDGVSISSPVLDRICGDSLFRTIASSGNRMLIQVRSSTPAASLPF-ATYYAICGGPIYGVIHSPKYPESYPPNSDCQWTIHVDENSQVAIEFVYFHLEQHKECIYDRLILTEGISKNSKKDGKFCGLIEKKTIVSKTNQISLRFFSDNSVQKTGFELRFTKELNECAT-DKNICHHYCVNTVGGFKCACRVGYSLSSNGFSCDSTCGGYLKASNGSISSPNFPEMYPNSKTCIWEIEAPDGYHIFLNFTKFNVEGMKTCAYDYVKIGDS--------EKLCGEYHEALLTTPRNRVRIEFSSDSSVERDGFFANFIADECQNDNAGCEHTCQNRLGSYVCTCNPGYILAEDKHNCKEGSCFFEVNAPAGDINSPNYPNDYPKGQNCSWHFVTTPGHRLMLTFSSFQVEEHAQCKYDAVSVYDGGDGSAQLAGVFCGLAPPPLLLSSSNELYLTFSSDASVSRRGFQAHYTSLCGGRLTAESTPGHIYSHATFSDSKYGKNQDCSWIVRAKSGRGVRIQFSTFNIESEEGCQYDYIEIYDGPETLERLGRFCGDTSPEVITSTGPELLLIMHTDNAEEEKGFVAEYREAPRSSSSKTRH >XP_043308815.1 bone morphogenetic protein 1 isoform X1 [Cervus canadensis] MPGVARPLDLADYTYDLGEEDDAEPLNYKDPGDIALDEEDQVQQAADLRQRATRRSSIKAARSHGRWSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKGHIQSPNYPDDYRPSKVCVWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSSSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVYDGRDSKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDTLHSRK >KAF4019395.1 hypothetical protein G4228_011326 [Cervus hanglu yarkandensis] LEALTRDSEDPGAKGSCADWQEADPVDSTGTGDIALDEEDQVQQAADLRQRATRRSSIKAARSHGRWSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKGHIQSPNYPDDYRPSKVCVWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSSSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVYDGRDSKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDTLHSRK >KAB0373058.1 hypothetical protein FD755_014717 [Muntiacus reevesi] MPGVARPLDLADYTYDLGEEDDAEPLNYKDPGDIALDEEDQVQQAADLRQRATRRSSIKAARSHGRWSRSRRAATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDRHVSIVRENIQPGQEYNFLKMEVQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIGQRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKIILNFTSMDLYRSWYDYVEVRDGFWRKAPLRGRFCGGKLPEPIVSTDSRLWVEFRSSSNWVGKGFFAVYEAICGGDVKGHIQSPNYPDDYRPSKVCVWRIQVSEGFHVGLTFQSFEIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGFAVNFFKEGMLVRGRGR--------------KCHRSPGRRQDSPRLRGPAACGGFLTKLNGSITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSKLHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDECSKDNGGCQQDCVNTFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSSSGTITSPNWPDKYPSKKECTWAISSTPGHRVKLTFMEMDIESQPECAYDHLEVYDGRDSKAPVLGRFCGSKKPEPVLATGNRMFLRFYSDNSVQRKGFQASHSTECGGQVRAEVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGYGVELVFQTFEVEEETDCGYDYMELFDGYDTAPRLGRYCGSGPPEEVYSAGDSVLVKFHSDDTITKKGFHLRYTSTKFQDTLHSRK >XP_004072530.1 bone morphogenetic protein 1 [Oryzias latipes] MDLSVRDLDAADPGYYVEPTATSEAIDYKDPGDIALDEEDKVDRIIDLAQRTVQNVNHTDE------QRRKRAATSRPERVWPEGVIPYVISGNFSGSQRAVFRQAMRHWEKHTCVTFIERTQEESYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDEHVSIIKDNIQPGQEYNFLKMEPGEVDSLGEVYDFDSIMHYARNTFSRGIFLDTILPRYDVNGVRPPIGQRTRLSKGDIAQARKLYKCSKCGESLQDSSGNFSSPGFPNGYSAYMHCIWRISVTPGEKIILNFTSMDLYRSWYDHVEIRDGYWRKAPLKGRFCGDKLPEPIISTDSRLWIEFRSSSNWVGKGFSAVYEAICGGDVKGQIQSPNYPDDYRPNKACIWKISVSEGYHVGLTFQSFEIERHDSCAYDYLEVRDGISENSPLLGRFCGYDKPDDIKTSSNHLWMKFVSDGSVNKAGFAANFFKEMDECSKPDNGRCEQRCVNTLGSYKCACDPGYELAADKRSCEAACGGFITKLNGSITSPGWPREYPPNKNCIWQLVAPTQYRITLLFDVFETEGNDVCKYDFVEVRSGLSADSKPHGKFCGSEKPEAITSQYNNMRIEFKSDNTVSKKGFKAQFFSDECSKENGGCQHDCVNTFGSYRCQCRSGFVLHENKHDCKEAGCDHTVNSVSGAITSPNWPDKYPSKKACTWALSTTPGHRIKIAFNEIDMEAHLDCAYDHIQIYDGRDAKAPSLGRFCGSKKPQPIISSGNKLFIRFFSDNSVQKKGFDASHSAECGGILKAEVKTKDLFSHAQFGDNNYPGASDCEWVISAEKGYGVELIFQTFEIEEEADCGYDYMELFDGADKSPRLGRYCGSGPPEEIYSAGDSIVIKFHSDDTINKKGFHVRYTSTKFQDTLHSRK >XP_030273707.1 bone morphogenetic protein 1 [Sparus aurata] MDLTARDLEAIDPGYYVESTATSEAIDYKDPGDIALDEEDKVDRVIDLAQRTVYTVNHTDS------HRRKRAATSRPERVWPEGVIPYVISGNFSGSQRAIFRQAMRHWEKHTCVTFIERTQEESYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDEHVSIIRDNIQPGQEYNFLKMEPGEVDSLGEVYDFDSIMHYARNTFSRGIFLDTILPRYDVNGVRPPIGQRTRLSKGDIAQARKLYKCSRCGDSLQDSSGNFSSPGFPNGYSAYMHCIWRISVTPGEKIILNFTSMDLYRSWYDHVEIRDGYWRKAPLKGRFCGDKLPEPIISTDSRLWIEFRSSSNWVGKGFSAVYEAICGGEVKGQIQSPNYPDDYRPNKVCVWKITVAQGYHVGLTFQSFEIERHDSCAYDYLEVRDGNSENSPLLGRFCGYDKPDDIKTSSNQLWMKFVSDGSVNKAGFAANFFKEMDECSKPDNGRCEQRCVNTLGSYKCACDPGYELAADKRSCEAACGGFITKLNGSITSPGWPREYPPNKNCIWQLVAPTQYRITLLFDVFETEGNDVCKYDYVEVRSGLSADSRLHGKFCGAEKPEAITSQYNNMRIEFKSDNTVSKKGFKAQFFSDECSKENGGCQHECVNTFGSYSCQCRSGFVLHENKHDCKEAGCDHTVNSVSGTITSPNWPDKYPSKKACTWALTTTPGHRIKIAFNEIDMEAHLECAYDHIEIYDGRDGKAPSMGRFCGTKKPPPITSSGNKLFVRFFSDNSVQKKGFEASHTAECGGRLKAEVKTKDLFSHAQFGDNNYPGASDCQWVISAEKGYGVELIFQTFEIEEEADCGYDYMELFDGADKSPRLGRYCGSGPPEEIYSAGDSIVIKFRSDDTINKKGFHVRYTSTKFQDTLHSRK >XP_015827829.1 PREDICTED: bone morphogenetic protein 1 [Nothobranchius furzeri] MDLSVSDLEAIDPGFYVEPSATSEAIDYKDPGDIALDEEDKVDRIIDLAQRTVQTFNHTDA------QRRKRAATSRLERVWPEGVIPYVISGNFSGSQRAIFRQAMRHWEKHTCVTFIERTQEESYIVFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDEHVSIIRDNIQQGQEYNFLKMEPGEVDSLGEVYDFDSIMHYARNTFSRGIFLDTILPRYDVNGVRPPIGQRTRLSKGDIAQARKLYKCSKCGDSLQESSGNFSSPGFPNGYSAYMHCIWRISVTPGEKIILNFTSMDLYRSWYDHVEIRDGYWRKAPLKGRFCGDKLPEPIISTDSRLWIEFRSSSNWVGKGFSAVYEAICGGEVKGQIQSPNYPDDYRPNKVCVWKISVSQGFHVGLTFQSFEIERHDSCAYDYLEVRDGLSENSPLLGRFCGYDKPDDIKTSSNHLWMKFVSDGSVNKAGFAANFFKETDECSKPDNGRCEQRCVNTLGSYKCACDPGYELAADKRSCEAACGGFITKLNDSITSPGWPREYPPNKNCIWQLVAPTQYRITLLFDVFETEGNDVCKYDYVEVRSGLSADSRLHGKFCGAEKPEAITSQYNNMRIEFKSDNTVSKKGFKAQFFSDECSKENGGCQHECVNTFGSYSCQCRSGFVLHENKHDCKEAGCDHTVNSVNGVITSPNWPDKYPSKKACTWALTTTPGHRIKIAFNEIDMEPHLECAYDHIEVYDGRDGKSPSLGRFCGSKKPPPIESSSNKLFIRFFSDNSVQKKGFEASHSAECGGRLKAEVKTKDLFSHAQFGDNNYPGASDCQWVISAEKGYGVELIFQTFEIEEEADCGYDYMELFDGADKSPRLGRYCGSGPPEEIYSAGDSIVIKFHSDDTINKKGFHVRYTSTKFQDTLHSRK >XP_018106279.1 bone morphogenetic protein 1 L homeolog isoform X1 [Xenopus laevis] MPWLGSGQEFLDYSYDLEE-VVEESIDYKDPGDIALDEEDKVARIVDLTKHTISTVSGAASGRRTRKSRERRAATSRPERVWPDGVIPYVISGNFSGSQRAIFRQAMRHWEKHTCVTFLERTDEDSYIIFTYRPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVIGFWHEHTRPDRDDHVSIIRENIQPGQEYNFLKMEPEEVESIGETYDFDSIMHYARNTFSRGIFLDTILPKYDVNGVRPPIGQRTRLSSGDIAQAKKLYRCPACGETLQDSQGNFSSPGFPNGYSAYMHCVWRLSVTPGEKIILNFTSLDLYRSWYDYIEVRDGFWKKAPLRGRFCGDKIPEPIISTESRLWIEFRSSSNWVGKGFQAVYEALCGGDVKGHIQSPNYPDDYRPNKACVWKLSVSEGFHVGISFQSFEIERHDSCAYDYLEIRDGSSESSPLIGRFCGYDKPDDIKSSTNQLWVKFVSDGSINKAGFSLNYFKEVDECSRPNNGGCEQRCVNTLGSYKCACDPGYELGPDKKSCEAACGGFLTKLNGSITSPGWPKEYPPNKNCVWQLVAPTQYRISLKFDQFETEGNDVCKYDFVEVRSGLTSDSKLHGKFCGTELPAVITSQYNNMRIEFKSDNTVSKKGFQANFFSDECSQDNGGCQHECTNTLGSYICQCRSGFTLHENKHDCKEAGCDHKVTGSTGTISSPNWPDKYPSKKICTWQITATPGHRAKLTVSEVDLESHQECLYDHVEVYSGCDAQSPALNRFCGSKIPDPIISPGNTMFLKFMSDNSVQKRGFLGELSSVCGGTLHAEVRTQDLYSHAKFGDDTHPSGTECLWHIVSEAGYGVELVFQSFELEEEPDCGYDYMELYDGPDGAPRLGRYCGSGPPEEVYSAGDALTIKFHADDTINKKGFHVRYTSTKFQDTLHARK >XP_040530575.1 tolloid-like protein 2 isoform X1 [Gallus gallus] MGRGAT---------AAGEPTAEEQMEYRDPGDIALDEDDQIDRTVDLTKHSAGNARHTSGKDESGMPRVRRATTSRAERIWPGGVIPYVIGGNFTGTQRAIFKQAMRHWEKHTCVTFVERTDEESFIVFTYRTCGCCSYVGRRGGGPQAISIGKNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQQGQEYNFLKMEAGEVNSLGETYDFDSIMHYARNTFSRGVFLDTILPRRDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDSTGNFSAPGFPSGYPSYSHCVWRISVTPGEKIMLNFTSMDLFKSWYDYVEVRDGYWRKAPLLGRFCGDKIPEPVISTDSRLWIEFRSSSNILGKGFFVVYEAICGGEVRGQIQSPNYPDDYRPSKECIWKITVSEGFHIGISFQAFEIEWHDACSYDYLEIRDGLTENSPLIGQFCGYEKPEDIKSSSNKIWMKFTSDATISKAGFAANFFKEMDECSQPDNGGCEQHCENTLGSYKCTCEPGYELTADKKSCEAACGGFITKLNGTITSPGWPKEYPTNKNCVWQVVAPAQYRISLQFEVFDLEGNDVCKYDYVEVRSGLATDSKLHGKFCGSEKPEVITSYSNNIRLEFKSDNTVSKKGFKVHFFSDECSKDNGGCQHECINTFGSYVCQCRNGFKLHENNHDCKEAGCEHKLSSAEGMMSSPNWPDKYPSRKECTWNISATPGHRVKVTFHEFEIEQHQECAYDHLEMYDGPNSKSPILGRFCGSKKPDPVVASTNKMFLRFYSDASVQRKGFQAKHSTVCGGLLKAEVQTKELYSHAQFGDNNYPGQANCDWVIVAEDGYGVELMFQTFEIEEEADCGYDYMEIYDGYDTAPRLGRFCGSGPLEEIYSAGDSIMIRFHTDDTINKKGFHAQYISTKFQDALHMRK >XP_031410433.1 tolloid-like protein 2 [Meleagris gallopavo] MAKHPE-------------------------GDIALDEDDQIDRTVDLTKHSAGNARHTSGKDESGMPRVRRATTSRAERIWPGGVIPYVIGGNFTGTQRAIFKQAMRHWEKHTCVTFVERTDEESFIVFTYRTCGCCSYVGRRGGGPQAISIGKNCDKFGIVAHELGHVVGFWHEHTRPDRDQHVTIIRENIQQGQEYNFLKMEAGEVNSLGETYDFDSIMHYARNTFSRGVFLDTILPRRDDNGVRPTIGQRVRLSQGDIAQARKLYKCPACGETLQDSTGNFSAPGFPSGYPSYSHCVWRISVTPGEKIMLNFTSMDLFKSWYDYVEVRDGYWRKAPLLGRFCGDKIPEPVISTDSRLWIEFRSSSNILGKGFFVVYEAICGGEIRGQIQSPNYPDDYRPSKECIWKITVSEGYHIGISFQAFEIEWHDACSYDYLEIRDGLTENSPLIGQFCGYEKPEDIKSSSNKIWMKFASDATISKAGFAANFFKEMDECSQPDNGGCEQHCENTLGSYKCTCEPGYELTADKKSCEAACGGFITKLNGTITSPGWPKEYPTNKNCIWQVVAPAQYRISLQFEVFDLEGNDVCKYDFVEVRSGLATDSKLHGKFCGSEKPEVITSYGNNMRLEFKSDNTVSKKGFKIHFFSDECSKDNGGCQHECINTFGSYVCQCRNGFKLHENNHDCKEAGCEHKLSSAEGMMSSPNWPDKYPSRKECTWNISATSGHRVKVTFNEFEIEQHQECAYDHLEMYDGPNSKSPILGRFCGSKKPDPVVASTNKMFLRFYSDASVQRKGFQAKHSTVCGGLLKAEVQTKELYSHAQFGDNNYPGQANCDWVIVAEDGYGVELIFQTFEIEEEADCGYDYMEIYDGYDTAPRLGRFCGSGPLEEIYSAGDSIMIRFHTDDTINKKGFHARYISTKFQDALHMRK
PhyML tree of selected proteins (XP_031410433_1_tolloid_like_protein_2__Meleagris_gallopavo_:0.01319962,XP_040530575_1_tolloid_like_protein_2_isoform_X1__Gallus_gallus_:0.00822652,(((tr_F1REM3_F1REM3_DANRE_Metalloendopeptidase_OS_Danio_rerio_OX_7955_GN_bmp1a_PE_4_SV_2:0.03015164,(XP_030273707_1_bone_morphogenetic_protein_1__Sparus_aurata_:0.00947429,(XP_004072530_1_bone_morphogenetic_protein_1__Oryzias_latipes_:0.03223868,XP_015827829_1_PREDICTED__bone_morphogenetic_protein_1__Nothobranchius_furzeri_:0.02194393):0.01350056):0.02161683):0.10680392,(((XP_021154607_1_bone_morphogenetic_protein_1__Columba_livia_:0.08894267,(XP_025066133_1_bone_morphogenetic_protein_1__Alligator_sinensis_:0.02752012,XP_019347110_1_PREDICTED__bone_morphogenetic_protein_1__Alligator_mississippiensis_:0.00458734):0.09046873):0.02299833,(((XP_024852018_1_bone_morphogenetic_protein_1_isoform_X1__Bos_taurus_:0.00000001,(KAB0373058_1_hypothetical_protein_FD755_014717__Muntiacus_reevesi_:0.02594986,(XP_043308815_1_bone_morphogenetic_protein_1_isoform_X1__Cervus_canadensis_:0.00000001,(KAF4019395_1_hypothetical_protein_G4228_011326__Cervus_hanglu_yarkandensis_:0.03506461,XP_020755633_1_bone_morphogenetic_protein_1__Odocoileus_virginianus_texanus_:0.00592368):0.00000001):0.00000001):0.00117588):0.00117949,(XP_014948597_2_bone_morphogenetic_protein_1_isoform_X3__Ovis_aries_:0.00000001,XP_017907774_1_PREDICTED__bone_morphogenetic_protein_1_isoform_X1__Capra_hircus_:0.0011756):0.0011754):0.00311381,(XP_020927995_1_LOW_QUALITY_PROTEIN__bone_morphogenetic_protein_1__Sus_scrofa_:0.00594535,(((XP_030869708_1_bone_morphogenetic_protein_1_isoform_X1__Gorilla_gorilla_gorilla_:0.00235585,((XP_002818918_1_bone_morphogenetic_protein_1_isoform_X1__Pongo_abelii_:0.00000001,(XP_016814692_1_bone_morphogenetic_protein_1_isoform_X1__Pan_troglodytes_:0.00000001,XP_003823651_1_bone_morphogenetic_protein_1_isoform_X1__Pan_paniscus_:0.00000001):0.00000001):0.00000001,(sp_P13497_BMP1_HUMAN_Bone_morphogenetic_protein_1_OS_Homo_sapiens_OX_9606_GN_BMP1_PE_1_SV_2:0.00000001,(sp_P13497_2_BMP1_HUMAN_Isoform_BMP1_1_of_Bone_morphogenetic_protein_1_OS_Homo_sapiens_OX_9606_GN_BMP1:0.01265265,(sp_P13497_5_BMP1_HUMAN_Isoform_BMP1_6_of_Bone_morphogenetic_protein_1_OS_Homo_sapiens_OX_9606_GN_BMP1:0.00000001,(sp_P13497_6_BMP1_HUMAN_Isoform_BMP1_7_of_Bone_morphogenetic_protein_1_OS_Homo_sapiens_OX_9606_GN_BMP1:0.00000001,(sp_P13497_4_BMP1_HUMAN_Isoform_BMP1_5_of_Bone_morphogenetic_protein_1_OS_Homo_sapiens_OX_9606_GN_BMP1:0.00000001,sp_P13497_3_BMP1_HUMAN_Isoform_BMP1_4_of_Bone_morphogenetic_protein_1_OS_Homo_sapiens_OX_9606_GN_BMP1:0.20990534):0.0421487):0.00000001):0.05516095):0.1085429):0.00235977):0.00000001):0.01159886,(NP_112613_1_bone_morphogenetic_protein_1_precursor__Rattus_norvegicus_:0.00235005,NP_033885_2_bone_morphogenetic_protein_1_precursor__Mus_musculus_:0.00356457):0.0141893):0.00546281,(XP_023108277_1_bone_morphogenetic_protein_1_isoform_X2__Felis_catus_:0.00954407,XP_038291401_1_bone_morphogenetic_protein_1_isoform_X1__Canis_lupus_familiaris_:0.00233261):0.00483847):0.00109198):0.00164638):0.09557754):0.0363929,(XP_040202086_1_bone_morphogenetic_protein_1_isoform_X1__Rana_temporaria_:0.16710391,XP_018106279_1_bone_morphogenetic_protein_1_L_homeolog_isoform_X1__Xenopus_laevis_:0.0587934):0.12170261):0.04033523):0.08424385,(XP_039272807_1_bone_morphogenetic_protein_1_like__Styela_clava_:0.43917244,((XP_038060664_1_bone_morphogenetic_protein_1_homolog_isoform_X1__Patiria_miniata_:0.25357385,XP_030834881_1_bone_morphogenetic_protein_1_homolog_isoform_X1__Strongylocentrotus_purpuratus_:0.31877166):0.26734331,(XP_031559878_1_tolloid_like_protein_1__Actinia_tenebrosa_:1.17258808,(NP_001360030_1_Zinc_metalloproteinase_nas_39__Caenorhabditis_elegans_:1.31260163,(CAE1240683_1_tok__Sepia_pharaonis_:0.45418584,(XP_006567027_2_tolloid_like_protein_1_isoform_X2__Apis_mellifera_:0.25585452,NP_001287510_1_tolkin__isoform_C__Drosophila_melanogaster_:0.47254426):0.21594186):0.10130105):0.16339302):0.0338358):0.14708262):0.15312541):0.17829059);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)