PB0172

DATABASE

Click here to access PB0172 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0172	Q9NQ30	Endothelial cell-specific molecule 1	ESM1	endocan	Homo_sapiens	Involved in angiogenesis; promotes angiogenic sprouting. May have potent implications in lung endothelial cell-leukocyte interactions.

Domains

Gene Ontology

PF00219 (IGFBP)

GO:0005171 (enables) hepatocyte growth factor receptor binding GO:0005178 (enables) integrin binding GO:0005515 (enables) protein binding GO:0001525 (involved in) angiogenesis GO:0002040 (involved in) sprouting angiogenesis GO:0008284 (involved in) positive regulation of cell population proliferation GO:1902204 (involved in) positive regulation of hepatocyte growth factor receptor signaling pathway GO:0005576 (located in) extracellular region

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|Q9NQ30|ESM1_HUMAN Endothelial cell-specific molecule 1 OS=Homo sapiens OX=9606 GN=ESM1 PE=1 SV=2 MKSVLLLTTLLVPAHLVAAWSNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAG RGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQSG ICDRGTGKCLKFPFFQYSVTKSSNRFVSLTEHDMASGDGNIVREEVVKENAAGSPVMRKW LNPR >sp|Q9NQ30-2|ESM1_HUMAN Isoform 2 of Endothelial cell-specific molecule 1 OS=Homo sapiens OX=9606 GN=ESM1 MKSVLLLTTLLVPAHLVAAWSNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAG RGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICKEHDMASGDGNIVREEVVKEN AAGSPVMRKWLNPR >tr|A0A0R4IF38|A0A0R4IF38_DANRE Endothelial cell-specific molecule 1 OS=Danio rerio OX=7955 GN=esm1 PE=4 SV=1 MRVFAILMFVLMVFFGETEAWGPGGKYAVNCPDKCNPALCGSTLRCRRTVLDDCGCCQVC AAGRGEHCYRTVSGMHGVKCGPGLFCDFYKDEDDYGDEYGICKDCMFGTYGMECRKTCDC KAGGLCDRETGACLSFKVLAKMAMLKSHSNEAGNEVGSGDTNTESSSSRASARNFLTPR
Selected proteins from model organisms >sp|Q9NQ30|ESM1_HUMAN Endothelial cell-specific molecule 1 OS=Homo sapiens OX=9606 GN=ESM1 PE=1 SV=2 MKSVLLLTTLLVPAHLVAAWSNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAG RGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQSG ICDRGTGKCLKFPFFQYSVTKSSNRFVSLTEHDMASGDGNIVREEVVKENAAGSPVMRKW LNPR >sp|Q9NQ30-2|ESM1_HUMAN Isoform 2 of Endothelial cell-specific molecule 1 OS=Homo sapiens OX=9606 GN=ESM1 MKSVLLLTTLLVPAHLVAAWSNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAG RGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICKEHDMASGDGNIVREEVVKEN AAGSPVMRKWLNPR >tr|A0A0R4IF38|A0A0R4IF38_DANRE Endothelial cell-specific molecule 1 OS=Danio rerio OX=7955 GN=esm1 PE=4 SV=1 MRVFAILMFVLMVFFGETEAWGPGGKYAVNCPDKCNPALCGSTLRCRRTVLDDCGCCQVC AAGRGEHCYRTVSGMHGVKCGPGLFCDFYKDEDDYGDEYGICKDCMFGTYGMECRKTCDC KAGGLCDRETGACLSFKVLAKMAMLKSHSNEAGNEVGSGDTNTESSSSRASARNFLTPR >NP_072126.1 endothelial cell-specific molecule 1 precursor [Rattus norvegicus] MKSLLLLTTLLIPLHLGMAWSAKYAVDCPEHCDNTECRSSLRCKRTVLDDCGCCQVCAAGPGETCYRTVS GMDGVKCGPGLKCHFYSEEDDFGDEFGVCKDCPYGTFGMDCKETCNCQSGICDRVTGRCLDFPFFQYAAA KSPSRTSASQTERDAASGDGNAVREEIGDRNAARPSVMKWLNPR >NP_076101.1 endothelial cell-specific molecule 1 precursor [Mus musculus] MKSLLLLTTLLVPLHLGMAWSAKYAVDCPEHCDKTECRSSLRCKRTVLDDCGCCQVCAAGPGETCYRTVS GMDGVKCGPGLKCHFYSEEDDFGDEFGICKDCPYGTFGMECKETCNCQSGICDRVTGRCLDFPFFQYAAA KSPSRTSASHTERDSASGDGNAVREEIGEGNAARPSVMKWLNPR >XP_428357.3 endothelial cell-specific molecule 1 [Gallus gallus] MKGFLLLTLLLMPAHAGAAWSAKYAVDCPEPCDSNACKSTLRCKRTVLDDCGCCRVCAAVLGETCYRTVS GMDGVKCGPGLKCQFYTEEDDFGDEFGICKECPYGTYGMECRKTCNCPSGICDRVTGKCLKFPFFQLSAS KPPNRRKIISHTDNDMASGDGNSVKEEFVKEKAIRTPVMKWLNPR >XP_518187.3 endothelial cell-specific molecule 1 [Pan troglodytes] MQNNHLNITDDISLGFSIPGWQQRVNPAFILDFINQNKRAWQEDSAAAGLRKLMTGKHAGNPVYKTHKRV GRGSATSLDGCFPPAKTTTAEPSRRQLGNMKSVLLLTTLLVPAHLVAAWSNNYAVDCPQHCDSSECKSSP RCKRTVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDC RETCNCQSGICDRGTGKCLKFPFFQYSVTKSSNRFVSLTEHDMASGDGNIVREEVVKENAAGSPVMRKWL NPR >XP_546319.2 endothelial cell-specific molecule 1 [Canis lupus familiaris] MKSLLLLLATLLVPAHLAAAWSARYAVDCPERCDSAGCKSSLRCKRTVLDDCGCCRVCAAGPGETCYRTV SAMDGVKCGPGLRCQFYSEEDDFGDEFGICKDCPYGTFGMDCKETCNCQSGICDRVTGKCLKFPFFQYSV AKASNRRFVSHTEHDMASGDGNAVREELVKENARSPVMKWLNPR >NP_001091570.1 endothelial cell-specific molecule 1 precursor [Bos taurus] MKRLLLLATLLVPAHLAAVWSRKYAVDCPERCDSSQCKSSSRCKRTVLDDCGCCRVCAAGLGETCYRTVS GMDGVKCGPGLRCQFYNEEDDFGDEFGICKDCPFGTFGMECKQICSCQSGICNRVTGKCLKFPFFQYSVA KATNQRFVSHTEHDVASGDGNAVREELVKENDAPSPVMKWLNPR >XP_002714077.2 PREDICTED: endothelial cell-specific molecule 1 [Oryctolagus cuniculus] MTGKHAGNPVYKTHQRVGREAQLPLWTAASRQPRLRRGEPSRSQAGNMKSFLLLTTLLVPAHLATAWSVK YAVDCPERCDSSECRSSLRCKRTVLDDCGCCRVCAAGLGETCYRTVAAMDGVKCGPGLRCQFYSEEDDFG DEFGICKDCPYGTFGMECKQTCNCQSGICDRVTGRCLKFPFFQYSVVKSSNRRFLPHSEHDMASGDGNAM REEIVKENVARSPVMKWLNPR >XP_002815601.1 endothelial cell-specific molecule 1 [Pongo abelii] MQNNHLNITDDISLGFSIPGWQQCVNPAFILDFINQNKRAWQEDSAAAGLRKLMTGKHAGNPVYKTHKRV GRGSATSLDGCFPPAKTTTGEPSRRQLGNMKSVLLLTTLLVPAHLVAAWSNNYAVDCPQQCDSSECKSSP RCKRTVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDC RETCNCQSGICDRGTGKCLKFPFFQYSVTKSSNRFVSLTEHDMASGDGNVVREEVVKENAAGSPVMRKWL NPR >XP_010723713.1 endothelial cell-specific molecule 1 [Meleagris gallopavo] MKGFLLLTLLLMPAHAGAAWSAKYAVDCPEPCDSNACKSTLRCKRTVLDDCGCCRVCAAVLGETCYRTVS GMDGVKCGPGLKCQFYTEEDDFGDEFGICKECPYGTYGMECRKTCNCPSGICDRVTGKCLKFPFFQLSAS KPPNRRKIISHTDNDMASGDGNSVKEEFIKEKAIHTPVMKWLNPR >XP_013840224.1 endothelial cell-specific molecule 1 isoform X1 [Sus scrofa] MTGKHAGNPVYKTLKRVGRGSAATLDGCFPPEKTPAREAEPGAAGNMKSLLLLATLLVPAHLAAAWSTKY AVDCPERCDTNECKSSLRCKRTVLDDCGCCRVCAAGLGETCYRTVSGMDGVKCGPGLRCQFYSEEDDFGD EFGICKDCPYGTFGMECKQTCSCQSGICDRVTGKCLKFPFQYSVAKAANRRFVSHTEHDMASGDGNAVRE ELMKENAARSPGMKWLNPR >XP_003827405.3 endothelial cell-specific molecule 1 [Pan paniscus] MQNNHLNITDDISLGFSIPGWQQRVNPAFILDFINQNKRAWQEDSAAAGLRKLMTGKHAGNPVYKTHKRV GRGSATSLDGCFPPAKTTTGEPSRRQLGNMKSVLLLTTLLVPAHLVAAWSNNYAVDCPQHCDSSECKSSP RCKRTVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDC RETCNCQSGICDRGTGKCLKFPFFQYSVTKSSNRFVSLTEHDMASGDGNIVREEVVKENAAGSPVMRKWL NPR >XP_003981465.1 endothelial cell-specific molecule 1 [Felis catus] MKSLLLLATLLVPAHLATTWSPKYAVDCPERCDRAECKSSLSCKRTVLDDCGCCRVCAAGLGETCYRTVS GMDGAKCGPGLRCQFYSEEDDFGDEFGICKDCPYGTFGMECKETCNCQSGICDRVTGKCLKFPFLQYSVA KTSNRRLVSTEHDMASGDGNTVTEELVKKNTRSPVMKWLNPR >XP_004017043.2 endothelial cell-specific molecule 1 [Ovis aries] MKCLLLLATLLVPAHLAGAWSLKYAVDCPEPCDSSQCNSGLHCKRTVLDDCGCCRVCAAELGETCYRTVS GMDGVKCGPGLRCQFDNKEDDFGDEIGICKDCPFGTFGVECKQICSCQSGICDRVTGKCLKLPFFQHSVT KATSQRFASHTEHDVASGDGNATREPVKENDARSPVTKRLNPR >XP_004058887.2 endothelial cell-specific molecule 1 [Gorilla gorilla gorilla] MTGKHAGNPVYKTHKRVGRGSATSLDGCFPPAKTTTGEPSRRQLGNMKSVLLLTTLLVPAHLVAAWSNNY AVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGE EFGICKDCPYGTFGMDCRETCNCQSGICDRGTGKCLKFPFFQYSVTKSSNRFVSLTEHDMASGDGNIVRE EVVKENAAGSPVMRKWLNPR >XP_023816191.1 endothelial cell-specific molecule 1 [Oryzias latipes] MSILLLTVLSSLVVRDADAWGASPKYAVNCPDRCSVERCGGTQRCARTVLDDCGCCQVCAAGRGEHCYRT VSGMHGVKCGPGLFCDFYKDEDDYGDEYGICKDCPYGTYGVECRKSCNCKGGICDRESGACLTLTFFSKI AGKLKTGPRPGETGSGEVISAHIAADQRADRSAAPKRLSPR >XP_005500944.1 endothelial cell-specific molecule 1 [Columba livia] MKGFLFLTLLLMPVRAGTTWSAKYAVDCPEPCDSNACKSTLRCKRTVLDDCGCCRVCAAALGETCYRTVS GMDGVKCGPGLKCQFYTEEDDFGDEFGICKECSYGTYGMECRKTCNCPSGICDRVTGKCLKFPFFQLSAS KPPNRRKIVSHTDNDMASGDGNSVKEEFVKEKAIRAPVMKWLNPR >XP_005694767.1 PREDICTED: endothelial cell-specific molecule 1 [Capra hircus] MKCLLLLATLLVPAHLEGAWSLKYAVDCPQPCDSSQCKSSLHCKRTVLDDCGCCRVCAAELGETCYRTVS GMDGVKCGPGLRCQFNNEEDDFGDEIGICKDCPFGTFGMECKQICSCQSGICDRVTGKCLKFPFFQHSVT KATSQRFASHTEHDVASGDGNATREELVKENDARSPVMKRLNPR >XP_006017352.1 endothelial cell-specific molecule 1 [Alligator sinensis] MKSFLFFTIILVLVHIRTAWSAKYAVDCPEPCDSNECKSTLRCKRTVLDDCGCCRVCAATLGETCYRTVS GMDGVKCGPGLKCQFYTEEDDFGDEFGICKECPYGTYGIECRKACNCQSGICDRVTGKCLKFPFFQLSAS KPPNRRKIISYTDNDMASGDGNAVKEEFVKEKGIDSPVMKWLNPR >XP_006268844.1 PREDICTED: endothelial cell-specific molecule 1 [Alligator mississippiensis] MKSFLFFTIILVLVHIRTAWSAKYAVDCPEPCDSNECKSTLRCKRTVLDDCGCCRVCAATLGETCYRTVS GMDGVKCGPGLKCQFYTEEDDFGDEFGICKECPYGTYGIECRKTCNCQSGICDRVTGKCLKFPFFQLSAS KPPNRRKIISYTDNDMASGDGNAVKEEFVKEKGIDSPVMKWLNPR >XP_015798398.1 PREDICTED: endothelial cell-specific molecule 1 isoform X1 [Nothobranchius furzeri] MSCRSVNPSLQRGSQVQEDNTSPFSLHLHTSIHPSIHSSTGMSLLLLAVLFSLLMEDAEAWGANAKYAVN CPDRCNAERCGGTQRCARTVLDDCGCCQVCAASRGEHCYRTVSGMHGAKCGPGLFCEFYKDEDDYGDEYG ICKDCPYGTYGVECRKTCSCKGGICDRETGACLTLTFFAKIASKLKTGQQAAGSEVGSGEVSSAQNPDRS TAPKRLNPR >XP_020752780.1 endothelial cell-specific molecule 1 [Odocoileus virginianus texanus] MTGKHAGNPVYKTHKRVGRRSATTLDGGFPPAETPPREAEPEPRENMKRLLLLATLLVPAHLAAVWSLKY AVDCPERCDSSQCRSSPRCKRTVLDDCGCCWVCAAGLGETCYRTVSGMDGVKCGPGLRCQFYDEEDDFGD EFGICKDCPFGTFGMECKQTCSCQSGICDKVTGKCLKFPFFQYSTAKATTQRFVSRTEHDVTSGDGNTVR EELVKEKDTRSPVTKWLNPR >XP_030291024.1 endothelial cell-specific molecule 1 [Sparus aurata] MKITQTADWSLHSSPPEVLRFSGSPPKKNPSEPTASLPACGPPPDRIPVMSLLLITVLSSLLVRDAEAWG ANVKYAVNCPDRCNTERCGGTQRCARTVLDDCGCCQVCAAGRGEHCYRTVSGMHGVKCGPGLFCEFYKDE DDYGDEYGICKDCLYGTYGVECRKTCNCKGGICDRETGACLTLKFFAKIASNLKNEPQAGVEVGSGEVST AQSTDPHTDRSTAPKRLIPR >XP_040195301.1 endothelial cell-specific molecule 1 [Rana temporaria] MKCCIFVASLLINMHFGTSRSSQYAVDCPDRCDGNECKSTVRCKRTVLDDCGCCRVCAAAAGETCYRTVS GMDGVKCGPGLTCQFFTEEDDFGDEFGVCRECPYGTYGMECRGTCNCPSGICDRVTGKCLKFPFFQFTGA KSPNKLRLNPDSEMASGDGNSVKPELAKDKSSRSPGIKWLNPR >KAB0353022.1 hypothetical protein FD754_017879 [Muntiacus muntjak] MKGLLLLATLLVPAHLAAVWSLKYAVDCPERCDSSQCKSSPRCKRTVLDDCGCCRVCAAGLGETCYRTVSGMDGVKCGPG LRCQFYNEEDDFGDEFGICKDCPFGTFGMECKQTCSCQSGICDRVTGKCLKFPFFQYSTAKATNQRFVSHTEHDVASGDG NAVREELVKEKDTRSPVTKWLNPR >KAB0369865.1 hypothetical protein FD755_018858 [Muntiacus reevesi] MKGLLLLATLLVPAHLAAVWSLKYAVDCPERCDSSQCKSSPRCKRTVLDDCGCCRVCAAGLGETCYRTVSGMDGVKCGPG LRCQFYNEEDDFGDEFGICKDCPFGTFGMECKQTCSCQSGICDRVTGKCLKFPFFQYSTAKATNQRLVSHTEHDVASGDG NAVREELVKEKETRSPVTKWLNPR >XP_043345009.1 endothelial cell-specific molecule 1 [Cervus canadensis] MKRLLLLVTLLVPAHLAAVWSFKYAVDCPERCDSRQCRSSPRCKRTVLDDCGCCWVCAAELGDTCYRTVSGMDGVKCGPG LRCQFYNEEDDFGDEFGICKDCPFGTFGMECKQTCSCQSGICDRVTGKCLKFPFQYSTAKATNQRFVTHTEHDVASGDGN AVREELVKEKDTLSPVTKWLNPR >XP_018099979.1 endothelial cell-specific molecule 1 [Xenopus laevis] MKCCLIVAALLINVHLGAARRAQYAVDCPDRCDSHDCRSTTRCKRTLLDDCGCCRVCAAAAGETCYRTVSGMDGVKCGPG LRCQFFTEEDDFGDEFGICRDCPYGTYGIECRRTCNCQSGICDRVTGKCLKFPFFQLTGGKTANKRRVASSSDPDMPSGD GHNDREENVKEKNGHSSGIKWLHPR
Mafft alignment of selected proteins >sp|Q9NQ30|ESM1_HUMAN Endothelial cell-specific molecule 1 OS=Homo sapiens OX=9606 GN=ESM1 PE=1 SV=2 ------------------------------------------------------------ --------------------------------------------MKS-VLLLTTLLVPAH LVAAW--SNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMD GMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQ-SGICDRGTGKCLKF PFFQYSVTKSSNR--FVSLTEHDMASGDGNIVREEVVKENAAGSPVMRKWLNPR >sp|Q9NQ30-2|ESM1_HUMAN Isoform 2 of Endothelial cell-specific molecule 1 OS=Homo sapiens OX=9606 GN=ESM1 ------------------------------------------------------------ --------------------------------------------MKS-VLLLTTLLVPAH LVAAW--SNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMD GMKCGPGLRCQPSNGEDPFGEEFGICK--------------------------------- --------------------EHDMASGDGNIVREEVVKENAAGSPVMRKWLNPR >tr|A0A0R4IF38|A0A0R4IF38_DANRE Endothelial cell-specific molecule 1 OS=Danio rerio OX=7955 GN=esm1 PE=4 SV=1 ------------------------------------------------------------ --------------------------------------------MRVFAILMFVLMVFFG ETEAWGPGGKYAVNCPDKCNPALCGSTLRCRRTVLDDCGCCQVCAAGRGEHCYRTVSGMH GVKCGPGLFCDFYKDEDDYGDEYGICKDCMFGTYGMECRKTCDCKAGGLCDRETGACLSF KVLAKMAMLKSHS----NEAGNEVGSGDTNT------ESSSSRASAR-NFLTPR >NP_072126.1 endothelial cell-specific molecule 1 precursor [Rattus norvegicus] ------------------------------------------------------------ --------------------------------------------MKS-LLLLTTLLIPLH LGMAW--SAKYAVDCPEHCDNTECRSSLRCKRTVLDDCGCCQVCAAGPGETCYRTVSGMD GVKCGPGLKCHFYSEEDDFGDEFGVCKDCPYGTFGMDCKETCNCQ-SGICDRVTGRCLDF PFFQYAAAKSPSRT-SASQTERDAASGDGNAVREEIGDRNAARPSVM-KWLNPR >NP_076101.1 endothelial cell-specific molecule 1 precursor [Mus musculus] ------------------------------------------------------------ --------------------------------------------MKS-LLLLTTLLVPLH LGMAW--SAKYAVDCPEHCDKTECRSSLRCKRTVLDDCGCCQVCAAGPGETCYRTVSGMD GVKCGPGLKCHFYSEEDDFGDEFGICKDCPYGTFGMECKETCNCQ-SGICDRVTGRCLDF PFFQYAAAKSPSRT-SASHTERDSASGDGNAVREEIGEGNAARPSVM-KWLNPR >XP_428357.3 endothelial cell-specific molecule 1 [Gallus gallus] ------------------------------------------------------------ --------------------------------------------MKG-FLLLTLLLMPAH AGAAW--SAKYAVDCPEPCDSNACKSTLRCKRTVLDDCGCCRVCAAVLGETCYRTVSGMD GVKCGPGLKCQFYTEEDDFGDEFGICKECPYGTYGMECRKTCNCP-SGICDRVTGKCLKF PFFQLSASKPPNRRKIISHTDNDMASGDGNSVKEEFVKEKAIRTPVM-KWLNPR >XP_518187.3 endothelial cell-specific molecule 1 [Pan troglodytes] MQNNHLNITDDISLGFSIPGWQQRVNPAFILDFINQNKRAWQEDSAAAGLRKLMTGKHAG N-PVYKTHKRVGR--GSATSLDGCFPPAKTTT--AEPSRRQLGNMKS-VLLLTTLLVPAH LVAAW--SNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMD GMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQ-SGICDRGTGKCLKF PFFQYSVTKSSNR--FVSLTEHDMASGDGNIVREEVVKENAAGSPVMRKWLNPR >XP_546319.2 endothelial cell-specific molecule 1 [Canis lupus familiaris] ------------------------------------------------------------ --------------------------------------------MKSLLLLLATLLVPAH LAAAW--SARYAVDCPERCDSAGCKSSLRCKRTVLDDCGCCRVCAAGPGETCYRTVSAMD GVKCGPGLRCQFYSEEDDFGDEFGICKDCPYGTFGMDCKETCNCQ-SGICDRVTGKCLKF PFFQYSVAKASNRR-FVSHTEHDMASGDGNAVREELVKEN-ARSPVM-KWLNPR >NP_001091570.1 endothelial cell-specific molecule 1 precursor [Bos taurus] ------------------------------------------------------------ --------------------------------------------MKR-LLLLATLLVPAH LAAVW--SRKYAVDCPERCDSSQCKSSSRCKRTVLDDCGCCRVCAAGLGETCYRTVSGMD GVKCGPGLRCQFYNEEDDFGDEFGICKDCPFGTFGMECKQICSCQ-SGICNRVTGKCLKF PFFQYSVAKATNQR-FVSHTEHDVASGDGNAVREELVKENDAPSPVM-KWLNPR >XP_002714077.2 PREDICTED: endothelial cell-specific molecule 1 [Oryctolagus cuniculus] -----------------------------------------------------MTGKHAG N-PVYKTHQRVGR--EAQLPL-WTAASRQPRLRRGEPSRSQAGNMKS-FLLLTTLLVPAH LATAW--SVKYAVDCPERCDSSECRSSLRCKRTVLDDCGCCRVCAAGLGETCYRTVAAMD GVKCGPGLRCQFYSEEDDFGDEFGICKDCPYGTFGMECKQTCNCQ-SGICDRVTGRCLKF PFFQYSVVKSSNRR-FLPHSEHDMASGDGNAMREEIVKENVARSPVM-KWLNPR >XP_002815601.1 endothelial cell-specific molecule 1 [Pongo abelii] MQNNHLNITDDISLGFSIPGWQQCVNPAFILDFINQNKRAWQEDSAAAGLRKLMTGKHAG N-PVYKTHKRVGR--GSATSLDGCFPPAKTTT--GEPSRRQLGNMKS-VLLLTTLLVPAH LVAAW--SNNYAVDCPQQCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMD GMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQ-SGICDRGTGKCLKF PFFQYSVTKSSNR--FVSLTEHDMASGDGNVVREEVVKENAAGSPVMRKWLNPR >XP_010723713.1 endothelial cell-specific molecule 1 [Meleagris gallopavo] ------------------------------------------------------------ --------------------------------------------MKG-FLLLTLLLMPAH AGAAW--SAKYAVDCPEPCDSNACKSTLRCKRTVLDDCGCCRVCAAVLGETCYRTVSGMD GVKCGPGLKCQFYTEEDDFGDEFGICKECPYGTYGMECRKTCNCP-SGICDRVTGKCLKF PFFQLSASKPPNRRKIISHTDNDMASGDGNSVKEEFIKEKAIHTPVM-KWLNPR >XP_013840224.1 endothelial cell-specific molecule 1 isoform X1 [Sus scrofa] -----------------------------------------------------MTGKHAG N-PVYKTLKRVGR--GSAATLDGCFPPEKTPAREAEP--GAAGNMKS-LLLLATLLVPAH LAAAW--STKYAVDCPERCDTNECKSSLRCKRTVLDDCGCCRVCAAGLGETCYRTVSGMD GVKCGPGLRCQFYSEEDDFGDEFGICKDCPYGTFGMECKQTCSCQ-SGICDRVTGKCLKF P-FQYSVAKAANRR-FVSHTEHDMASGDGNAVREELMKENAARSPGM-KWLNPR >XP_003827405.3 endothelial cell-specific molecule 1 [Pan paniscus] MQNNHLNITDDISLGFSIPGWQQRVNPAFILDFINQNKRAWQEDSAAAGLRKLMTGKHAG N-PVYKTHKRVGR--GSATSLDGCFPPAKTTT--GEPSRRQLGNMKS-VLLLTTLLVPAH LVAAW--SNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMD GMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQ-SGICDRGTGKCLKF PFFQYSVTKSSNR--FVSLTEHDMASGDGNIVREEVVKENAAGSPVMRKWLNPR >XP_003981465.1 endothelial cell-specific molecule 1 [Felis catus] ------------------------------------------------------------ --------------------------------------------MKS-LLLLATLLVPAH LATTW--SPKYAVDCPERCDRAECKSSLSCKRTVLDDCGCCRVCAAGLGETCYRTVSGMD GAKCGPGLRCQFYSEEDDFGDEFGICKDCPYGTFGMECKETCNCQ-SGICDRVTGKCLKF PFLQYSVAKTSNRR-LVS-TEHDMASGDGNTVTEELVKKN-TRSPVM-KWLNPR >XP_004017043.2 endothelial cell-specific molecule 1 [Ovis aries] ------------------------------------------------------------ --------------------------------------------MKC-LLLLATLLVPAH LAGAW--SLKYAVDCPEPCDSSQCNSGLHCKRTVLDDCGCCRVCAAELGETCYRTVSGMD GVKCGPGLRCQFDNKEDDFGDEIGICKDCPFGTFGVECKQICSCQ-SGICDRVTGKCLKL PFFQHSVTKATSQR-FASHTEHDVASGDGNATREP-VKENDARSPVT-KRLNPR >XP_004058887.2 endothelial cell-specific molecule 1 [Gorilla gorilla gorilla] -----------------------------------------------------MTGKHAG N-PVYKTHKRVGR--GSATSLDGCFPPAKTTT--GEPSRRQLGNMKS-VLLLTTLLVPAH LVAAW--SNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMD GMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQ-SGICDRGTGKCLKF PFFQYSVTKSSNR--FVSLTEHDMASGDGNIVREEVVKENAAGSPVMRKWLNPR >XP_023816191.1 endothelial cell-specific molecule 1 [Oryzias latipes] ------------------------------------------------------------ --------------------------------------------MSI-LLLTVLSSLVVR DADAWGASPKYAVNCPDRCSVERCGGTQRCARTVLDDCGCCQVCAAGRGEHCYRTVSGMH GVKCGPGLFCDFYKDEDDYGDEYGICKDCPYGTYGVECRKSCNCK-GGICDRESGACLTL TFFSKIAGKLKTGP---RP--GETGSGEVISAH-IAADQRADRSAAP-KRLSPR >XP_005500944.1 endothelial cell-specific molecule 1 [Columba livia] ------------------------------------------------------------ --------------------------------------------MKG-FLFLTLLLMPVR AGTTW--SAKYAVDCPEPCDSNACKSTLRCKRTVLDDCGCCRVCAAALGETCYRTVSGMD GVKCGPGLKCQFYTEEDDFGDEFGICKECSYGTYGMECRKTCNCP-SGICDRVTGKCLKF PFFQLSASKPPNRRKIVSHTDNDMASGDGNSVKEEFVKEKAIRAPVM-KWLNPR >XP_005694767.1 PREDICTED: endothelial cell-specific molecule 1 [Capra hircus] ------------------------------------------------------------ --------------------------------------------MKC-LLLLATLLVPAH LEGAW--SLKYAVDCPQPCDSSQCKSSLHCKRTVLDDCGCCRVCAAELGETCYRTVSGMD GVKCGPGLRCQFNNEEDDFGDEIGICKDCPFGTFGMECKQICSCQ-SGICDRVTGKCLKF PFFQHSVTKATSQR-FASHTEHDVASGDGNATREELVKENDARSPVM-KRLNPR >XP_006017352.1 endothelial cell-specific molecule 1 [Alligator sinensis] ------------------------------------------------------------ --------------------------------------------MKS-FLFFTIILVLVH IRTAW--SAKYAVDCPEPCDSNECKSTLRCKRTVLDDCGCCRVCAATLGETCYRTVSGMD GVKCGPGLKCQFYTEEDDFGDEFGICKECPYGTYGIECRKACNCQ-SGICDRVTGKCLKF PFFQLSASKPPNRRKIISYTDNDMASGDGNAVKEEFVKEKGIDSPVM-KWLNPR >XP_006268844.1 PREDICTED: endothelial cell-specific molecule 1 [Alligator mississippiensis] ------------------------------------------------------------ --------------------------------------------MKS-FLFFTIILVLVH IRTAW--SAKYAVDCPEPCDSNECKSTLRCKRTVLDDCGCCRVCAATLGETCYRTVSGMD GVKCGPGLKCQFYTEEDDFGDEFGICKECPYGTYGIECRKTCNCQ-SGICDRVTGKCLKF PFFQLSASKPPNRRKIISYTDNDMASGDGNAVKEEFVKEKGIDSPVM-KWLNPR >XP_015798398.1 PREDICTED: endothelial cell-specific molecule 1 isoform X1 [Nothobranchius furzeri] -----------------------------------------------------M------ --SCRSVNPSLQR--GSQVQEDNTSPFSLHLHTSIHPSIHSSTGMSL-LLLAVLFSLLME DAEAWGANAKYAVNCPDRCNAERCGGTQRCARTVLDDCGCCQVCAASRGEHCYRTVSGMH GAKCGPGLFCEFYKDEDDYGDEYGICKDCPYGTYGVECRKTCSCK-GGICDRETGACLTL TFFAKIASKLKTGQ---QAAGSEVGSGEVSSAQ------NPDRSTAP-KRLNPR >XP_020752780.1 endothelial cell-specific molecule 1 [Odocoileus virginianus texanus] -----------------------------------------------------MTGKHAG N-PVYKTHKRVGR--RSATTLDGGFPPAETPPREAEP--EPRENMKR-LLLLATLLVPAH LAAVW--SLKYAVDCPERCDSSQCRSSPRCKRTVLDDCGCCWVCAAGLGETCYRTVSGMD GVKCGPGLRCQFYDEEDDFGDEFGICKDCPFGTFGMECKQTCSCQ-SGICDKVTGKCLKF PFFQYSTAKATTQR-FVSRTEHDVTSGDGNTVREELVKEKDTRSPVT-KWLNPR >XP_030291024.1 endothelial cell-specific molecule 1 [Sparus aurata] -----------------------------------------------------MKITQTA DWSLHSSPPEVLRFSGSPPKKNPSEPTA--SLPACGPPPDRIPVMSL-LLITVLSSLLVR DAEAWGANVKYAVNCPDRCNTERCGGTQRCARTVLDDCGCCQVCAAGRGEHCYRTVSGMH GVKCGPGLFCEFYKDEDDYGDEYGICKDCLYGTYGVECRKTCNCK-GGICDRETGACLTL KFFAKIASNLKNEP---QA-GVEVGSGEVSTAQ--STDPHTDRSTAP-KRLIPR >XP_040195301.1 endothelial cell-specific molecule 1 [Rana temporaria] ------------------------------------------------------------ --------------------------------------------MKC-CIFVASLLINMH FGTSR--SSQYAVDCPDRCDGNECKSTVRCKRTVLDDCGCCRVCAAAAGETCYRTVSGMD GVKCGPGLTCQFFTEEDDFGDEFGVCRECPYGTYGMECRGTCNCP-SGICDRVTGKCLKF PFFQFTGAKSPNKLRL--NPDSEMASGDGNSVKPELAKDKSSRSPGI-KWLNPR >KAB0353022.1 hypothetical protein FD754_017879 [Muntiacus muntjak] ------------------------------------------------------------ --------------------------------------------MKG-LLLLATLLVPAH LAAVW--SLKYAVDCPERCDSSQCKSSPRCKRTVLDDCGCCRVCAAGLGETCYRTVSGMD GVKCGPGLRCQFYNEEDDFGDEFGICKDCPFGTFGMECKQTCSCQ-SGICDRVTGKCLKF PFFQYSTAKATNQR-FVSHTEHDVASGDGNAVREELVKEKDTRSPVT-KWLNPR >KAB0369865.1 hypothetical protein FD755_018858 [Muntiacus reevesi] ------------------------------------------------------------ --------------------------------------------MKG-LLLLATLLVPAH LAAVW--SLKYAVDCPERCDSSQCKSSPRCKRTVLDDCGCCRVCAAGLGETCYRTVSGMD GVKCGPGLRCQFYNEEDDFGDEFGICKDCPFGTFGMECKQTCSCQ-SGICDRVTGKCLKF PFFQYSTAKATNQR-LVSHTEHDVASGDGNAVREELVKEKETRSPVT-KWLNPR >XP_043345009.1 endothelial cell-specific molecule 1 [Cervus canadensis] ------------------------------------------------------------ --------------------------------------------MKR-LLLLVTLLVPAH LAAVW--SFKYAVDCPERCDSRQCRSSPRCKRTVLDDCGCCWVCAAELGDTCYRTVSGMD GVKCGPGLRCQFYNEEDDFGDEFGICKDCPFGTFGMECKQTCSCQ-SGICDRVTGKCLKF P-FQYSTAKATNQR-FVTHTEHDVASGDGNAVREELVKEKDTLSPVT-KWLNPR >XP_018099979.1 endothelial cell-specific molecule 1 [Xenopus laevis] ------------------------------------------------------------ --------------------------------------------MKC-CLIVAALLINVH LGAAR--RAQYAVDCPDRCDSHDCRSTTRCKRTLLDDCGCCRVCAAAAGETCYRTVSGMD GVKCGPGLRCQFFTEEDDFGDEFGICRDCPYGTYGIECRRTCNCQ-SGICDRVTGKCLKF PFFQLTGGKTANKRRVASSSDPDMPSGDGHNDREENVKEKNGHSSGI-KWLHPR
BMGE Cleaned alignment of selected proteins >sp|Q9NQ30|ESM1_HUMAN Endothelial cell-specific molecule 1 OS=Homo sapiens OX=9606 GN=ESM1 PE=1 SV=2 VLLLTTLLVPAHLVAAWSNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQSGICDRGTGKCLKFPFFQYSVTKSSNR-FVSLTEHDMASGDGNIVREEVVKENAAGSPVMKWLNPR >sp|Q9NQ30-2|ESM1_HUMAN Isoform 2 of Endothelial cell-specific molecule 1 OS=Homo sapiens OX=9606 GN=ESM1 VLLLTTLLVPAHLVAAWSNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICK---------------------------------------------------EHDMASGDGNIVREEVVKENAAGSPVMKWLNPR >tr|A0A0R4IF38|A0A0R4IF38_DANRE Endothelial cell-specific molecule 1 OS=Danio rerio OX=7955 GN=esm1 PE=4 SV=1 AILMFVLMVFFGETEAWGGKYAVNCPDKCNPALCGSTLRCRRTVLDDCGCCQVCAAGRGEHCYRTVSGMHGVKCGPGLFCDFYKDEDDYGDEYGICKDCMFGTYGMECRKTCDCKGGLCDRETGACLSFKVLAKMAMLKSHS---NEAGNEVGSGDTNT------ESSSSRASARNFLTPR >NP_072126.1 endothelial cell-specific molecule 1 precursor [Rattus norvegicus] LLLLTTLLIPLHLGMAWSAKYAVDCPEHCDNTECRSSLRCKRTVLDDCGCCQVCAAGPGETCYRTVSGMDGVKCGPGLKCHFYSEEDDFGDEFGVCKDCPYGTFGMDCKETCNCQSGICDRVTGRCLDFPFFQYAAAKSPSRTSASQTERDAASGDGNAVREEIGDRNAARPSVMKWLNPR >NP_076101.1 endothelial cell-specific molecule 1 precursor [Mus musculus] LLLLTTLLVPLHLGMAWSAKYAVDCPEHCDKTECRSSLRCKRTVLDDCGCCQVCAAGPGETCYRTVSGMDGVKCGPGLKCHFYSEEDDFGDEFGICKDCPYGTFGMECKETCNCQSGICDRVTGRCLDFPFFQYAAAKSPSRTSASHTERDSASGDGNAVREEIGEGNAARPSVMKWLNPR >XP_428357.3 endothelial cell-specific molecule 1 [Gallus gallus] FLLLTLLLMPAHAGAAWSAKYAVDCPEPCDSNACKSTLRCKRTVLDDCGCCRVCAAVLGETCYRTVSGMDGVKCGPGLKCQFYTEEDDFGDEFGICKECPYGTYGMECRKTCNCPSGICDRVTGKCLKFPFFQLSASKPPNRRIISHTDNDMASGDGNSVKEEFVKEKAIRTPVMKWLNPR >XP_518187.3 endothelial cell-specific molecule 1 [Pan troglodytes] VLLLTTLLVPAHLVAAWSNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQSGICDRGTGKCLKFPFFQYSVTKSSNR-FVSLTEHDMASGDGNIVREEVVKENAAGSPVMKWLNPR >XP_546319.2 endothelial cell-specific molecule 1 [Canis lupus familiaris] LLLLATLLVPAHLAAAWSARYAVDCPERCDSAGCKSSLRCKRTVLDDCGCCRVCAAGPGETCYRTVSAMDGVKCGPGLRCQFYSEEDDFGDEFGICKDCPYGTFGMDCKETCNCQSGICDRVTGKCLKFPFFQYSVAKASNRRFVSHTEHDMASGDGNAVREELVKEN-ARSPVMKWLNPR >NP_001091570.1 endothelial cell-specific molecule 1 precursor [Bos taurus] LLLLATLLVPAHLAAVWSRKYAVDCPERCDSSQCKSSSRCKRTVLDDCGCCRVCAAGLGETCYRTVSGMDGVKCGPGLRCQFYNEEDDFGDEFGICKDCPFGTFGMECKQICSCQSGICNRVTGKCLKFPFFQYSVAKATNQRFVSHTEHDVASGDGNAVREELVKENDAPSPVMKWLNPR >XP_002714077.2 PREDICTED: endothelial cell-specific molecule 1 [Oryctolagus cuniculus] FLLLTTLLVPAHLATAWSVKYAVDCPERCDSSECRSSLRCKRTVLDDCGCCRVCAAGLGETCYRTVAAMDGVKCGPGLRCQFYSEEDDFGDEFGICKDCPYGTFGMECKQTCNCQSGICDRVTGRCLKFPFFQYSVVKSSNRRFLPHSEHDMASGDGNAMREEIVKENVARSPVMKWLNPR >XP_002815601.1 endothelial cell-specific molecule 1 [Pongo abelii] VLLLTTLLVPAHLVAAWSNNYAVDCPQQCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQSGICDRGTGKCLKFPFFQYSVTKSSNR-FVSLTEHDMASGDGNVVREEVVKENAAGSPVMKWLNPR >XP_010723713.1 endothelial cell-specific molecule 1 [Meleagris gallopavo] FLLLTLLLMPAHAGAAWSAKYAVDCPEPCDSNACKSTLRCKRTVLDDCGCCRVCAAVLGETCYRTVSGMDGVKCGPGLKCQFYTEEDDFGDEFGICKECPYGTYGMECRKTCNCPSGICDRVTGKCLKFPFFQLSASKPPNRRIISHTDNDMASGDGNSVKEEFIKEKAIHTPVMKWLNPR >XP_013840224.1 endothelial cell-specific molecule 1 isoform X1 [Sus scrofa] LLLLATLLVPAHLAAAWSTKYAVDCPERCDTNECKSSLRCKRTVLDDCGCCRVCAAGLGETCYRTVSGMDGVKCGPGLRCQFYSEEDDFGDEFGICKDCPYGTFGMECKQTCSCQSGICDRVTGKCLKFP-FQYSVAKAANRRFVSHTEHDMASGDGNAVREELMKENAARSPGMKWLNPR >XP_003827405.3 endothelial cell-specific molecule 1 [Pan paniscus] VLLLTTLLVPAHLVAAWSNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQSGICDRGTGKCLKFPFFQYSVTKSSNR-FVSLTEHDMASGDGNIVREEVVKENAAGSPVMKWLNPR >XP_003981465.1 endothelial cell-specific molecule 1 [Felis catus] LLLLATLLVPAHLATTWSPKYAVDCPERCDRAECKSSLSCKRTVLDDCGCCRVCAAGLGETCYRTVSGMDGAKCGPGLRCQFYSEEDDFGDEFGICKDCPYGTFGMECKETCNCQSGICDRVTGKCLKFPFLQYSVAKTSNRRLVS-TEHDMASGDGNTVTEELVKKN-TRSPVMKWLNPR >XP_004017043.2 endothelial cell-specific molecule 1 [Ovis aries] LLLLATLLVPAHLAGAWSLKYAVDCPEPCDSSQCNSGLHCKRTVLDDCGCCRVCAAELGETCYRTVSGMDGVKCGPGLRCQFDNKEDDFGDEIGICKDCPFGTFGVECKQICSCQSGICDRVTGKCLKLPFFQHSVTKATSQRFASHTEHDVASGDGNATREP-VKENDARSPVTKRLNPR >XP_004058887.2 endothelial cell-specific molecule 1 [Gorilla gorilla gorilla] VLLLTTLLVPAHLVAAWSNNYAVDCPQHCDSSECKSSPRCKRTVLDDCGCCRVCAAGRGETCYRTVSGMDGMKCGPGLRCQPSNGEDPFGEEFGICKDCPYGTFGMDCRETCNCQSGICDRGTGKCLKFPFFQYSVTKSSNR-FVSLTEHDMASGDGNIVREEVVKENAAGSPVMKWLNPR >XP_023816191.1 endothelial cell-specific molecule 1 [Oryzias latipes] LLLTVLSSLVVRDADAWSPKYAVNCPDRCSVERCGGTQRCARTVLDDCGCCQVCAAGRGEHCYRTVSGMHGVKCGPGLFCDFYKDEDDYGDEYGICKDCPYGTYGVECRKSCNCKGGICDRESGACLTLTFFSKIAGKLKTGP--RP--GETGSGEVISAH-IAADQRADRSAAPKRLSPR >XP_005500944.1 endothelial cell-specific molecule 1 [Columba livia] FLFLTLLLMPVRAGTTWSAKYAVDCPEPCDSNACKSTLRCKRTVLDDCGCCRVCAAALGETCYRTVSGMDGVKCGPGLKCQFYTEEDDFGDEFGICKECSYGTYGMECRKTCNCPSGICDRVTGKCLKFPFFQLSASKPPNRRIVSHTDNDMASGDGNSVKEEFVKEKAIRAPVMKWLNPR >XP_005694767.1 PREDICTED: endothelial cell-specific molecule 1 [Capra hircus] LLLLATLLVPAHLEGAWSLKYAVDCPQPCDSSQCKSSLHCKRTVLDDCGCCRVCAAELGETCYRTVSGMDGVKCGPGLRCQFNNEEDDFGDEIGICKDCPFGTFGMECKQICSCQSGICDRVTGKCLKFPFFQHSVTKATSQRFASHTEHDVASGDGNATREELVKENDARSPVMKRLNPR >XP_006017352.1 endothelial cell-specific molecule 1 [Alligator sinensis] FLFFTIILVLVHIRTAWSAKYAVDCPEPCDSNECKSTLRCKRTVLDDCGCCRVCAATLGETCYRTVSGMDGVKCGPGLKCQFYTEEDDFGDEFGICKECPYGTYGIECRKACNCQSGICDRVTGKCLKFPFFQLSASKPPNRRIISYTDNDMASGDGNAVKEEFVKEKGIDSPVMKWLNPR >XP_006268844.1 PREDICTED: endothelial cell-specific molecule 1 [Alligator mississippiensis] FLFFTIILVLVHIRTAWSAKYAVDCPEPCDSNECKSTLRCKRTVLDDCGCCRVCAATLGETCYRTVSGMDGVKCGPGLKCQFYTEEDDFGDEFGICKECPYGTYGIECRKTCNCQSGICDRVTGKCLKFPFFQLSASKPPNRRIISYTDNDMASGDGNAVKEEFVKEKGIDSPVMKWLNPR >XP_015798398.1 PREDICTED: endothelial cell-specific molecule 1 isoform X1 [Nothobranchius furzeri] LLLAVLFSLLMEDAEAWNAKYAVNCPDRCNAERCGGTQRCARTVLDDCGCCQVCAASRGEHCYRTVSGMHGAKCGPGLFCEFYKDEDDYGDEYGICKDCPYGTYGVECRKTCSCKGGICDRETGACLTLTFFAKIASKLKTGQ--QAAGSEVGSGEVSSAQ------NPDRSTAPKRLNPR >XP_020752780.1 endothelial cell-specific molecule 1 [Odocoileus virginianus texanus] LLLLATLLVPAHLAAVWSLKYAVDCPERCDSSQCRSSPRCKRTVLDDCGCCWVCAAGLGETCYRTVSGMDGVKCGPGLRCQFYDEEDDFGDEFGICKDCPFGTFGMECKQTCSCQSGICDKVTGKCLKFPFFQYSTAKATTQRFVSRTEHDVTSGDGNTVREELVKEKDTRSPVTKWLNPR >XP_030291024.1 endothelial cell-specific molecule 1 [Sparus aurata] LLITVLSSLLVRDAEAWNVKYAVNCPDRCNTERCGGTQRCARTVLDDCGCCQVCAAGRGEHCYRTVSGMHGVKCGPGLFCEFYKDEDDYGDEYGICKDCLYGTYGVECRKTCNCKGGICDRETGACLTLKFFAKIASNLKNEP--QA-GVEVGSGEVSTAQ--STDPHTDRSTAPKRLIPR >XP_040195301.1 endothelial cell-specific molecule 1 [Rana temporaria] CIFVASLLINMHFGTSRSSQYAVDCPDRCDGNECKSTVRCKRTVLDDCGCCRVCAAAAGETCYRTVSGMDGVKCGPGLTCQFFTEEDDFGDEFGVCRECPYGTYGMECRGTCNCPSGICDRVTGKCLKFPFFQFTGAKSPNKLL--NPDSEMASGDGNSVKPELAKDKSSRSPGIKWLNPR >KAB0353022.1 hypothetical protein FD754_017879 [Muntiacus muntjak] LLLLATLLVPAHLAAVWSLKYAVDCPERCDSSQCKSSPRCKRTVLDDCGCCRVCAAGLGETCYRTVSGMDGVKCGPGLRCQFYNEEDDFGDEFGICKDCPFGTFGMECKQTCSCQSGICDRVTGKCLKFPFFQYSTAKATNQRFVSHTEHDVASGDGNAVREELVKEKDTRSPVTKWLNPR >KAB0369865.1 hypothetical protein FD755_018858 [Muntiacus reevesi] LLLLATLLVPAHLAAVWSLKYAVDCPERCDSSQCKSSPRCKRTVLDDCGCCRVCAAGLGETCYRTVSGMDGVKCGPGLRCQFYNEEDDFGDEFGICKDCPFGTFGMECKQTCSCQSGICDRVTGKCLKFPFFQYSTAKATNQRLVSHTEHDVASGDGNAVREELVKEKETRSPVTKWLNPR >XP_043345009.1 endothelial cell-specific molecule 1 [Cervus canadensis] LLLLVTLLVPAHLAAVWSFKYAVDCPERCDSRQCRSSPRCKRTVLDDCGCCWVCAAELGDTCYRTVSGMDGVKCGPGLRCQFYNEEDDFGDEFGICKDCPFGTFGMECKQTCSCQSGICDRVTGKCLKFP-FQYSTAKATNQRFVTHTEHDVASGDGNAVREELVKEKDTLSPVTKWLNPR >XP_018099979.1 endothelial cell-specific molecule 1 [Xenopus laevis] CLIVAALLINVHLGAARRAQYAVDCPDRCDSHDCRSTTRCKRTLLDDCGCCRVCAAAAGETCYRTVSGMDGVKCGPGLRCQFFTEEDDFGDEFGICRDCPYGTYGIECRRTCNCQSGICDRVTGKCLKFPFFQLTGGKTANKRVASSSDPDMPSGDGHNDREENVKEKNGHSSGIKWLHPR
PhyML tree of selected proteins ((((((XP_003981465_1_endothelial_cell_specific_molecule_1__Felis_catus_:0.08366863,(XP_546319_2_endothelial_cell_specific_molecule_1__Canis_lupus_familiaris_:0.03581819,(XP_013840224_1_endothelial_cell_specific_molecule_1_isoform_X1__Sus_scrofa_:0.03339049,((NP_001091570_1_endothelial_cell_specific_molecule_1_precursor__Bos_taurus_:0.02339774,(XP_004017043_2_endothelial_cell_specific_molecule_1__Ovis_aries_:0.04742692,XP_005694767_1_PREDICTED__endothelial_cell_specific_molecule_1__Capra_hircus_:0.01048334):0.07960236):0.00566412,((XP_043345009_1_endothelial_cell_specific_molecule_1__Cervus_canadensis_:0.04198613,XP_020752780_1_endothelial_cell_specific_molecule_1__Odocoileus_virginianus_texanus_:0.03546605):0.0108622,(KAB0369865_1_hypothetical_protein_FD755_018858__Muntiacus_reevesi_:0.01121865,KAB0353022_1_hypothetical_protein_FD754_017879__Muntiacus_muntjak_:0.00000001):0.00000001):0.02917598):0.05372256):0.0144017):0.00860599):0.01216384,(XP_002714077_2_PREDICTED__endothelial_cell_specific_molecule_1__Oryctolagus_cuniculus_:0.07835061,(XP_002815601_1_endothelial_cell_specific_molecule_1__Pongo_abelii_:0.00000001,((XP_003827405_3_endothelial_cell_specific_molecule_1__Pan_paniscus_:0.00000001,(XP_518187_3_endothelial_cell_specific_molecule_1__Pan_troglodytes_:0.00000001,(sp_Q9NQ30_ESM1_HUMAN_Endothelial_cell_specific_molecule_1_OS_Homo_sapiens_OX_9606_GN_ESM1_PE_1_SV_2:0.00000001,XP_004058887_2_endothelial_cell_specific_molecule_1__Gorilla_gorilla_gorilla_:0.00000001):0.00000001):0.00000001):0.00000001,sp_Q9NQ30_2_ESM1_HUMAN_Isoform_2_of_Endothelial_cell_specific_molecule_1_OS_Homo_sapiens_OX_9606_GN_ESM1:0.00000001):0.01101018):0.16226517):0.00000001):0.02540634,(NP_072126_1_endothelial_cell_specific_molecule_1_precursor__Rattus_norvegicus_:0.04455021,NP_076101_1_endothelial_cell_specific_molecule_1_precursor__Mus_musculus_:0.00222611):0.17244055):0.08340956,(tr_A0A0R4IF38_A0A0R4IF38_DANRE_Endothelial_cell_specific_molecule_1_OS_Danio_rerio_OX_7955_GN_esm1_PE_4_SV_1:0.34171924,(XP_015798398_1_PREDICTED__endothelial_cell_specific_molecule_1_isoform_X1__Nothobranchius_furzeri_:0.05343884,(XP_023816191_1_endothelial_cell_specific_molecule_1__Oryzias_latipes_:0.16585395,XP_030291024_1_endothelial_cell_specific_molecule_1__Sparus_aurata_:0.08767529):0.02630115):0.2934028):0.78388787):0.03111046,((XP_005500944_1_endothelial_cell_specific_molecule_1__Columba_livia_:0.02592295,(XP_428357_3_endothelial_cell_specific_molecule_1__Gallus_gallus_:0.00000001,XP_010723713_1_endothelial_cell_specific_molecule_1__Meleagris_gallopavo_:0.01119718):0.02855848):0.0340012,(XP_006017352_1_endothelial_cell_specific_molecule_1__Alligator_sinensis_:0.00553072,XP_006268844_1_PREDICTED__endothelial_cell_specific_molecule_1__Alligator_mississippiensis_:0.00000001):0.0705344):0.05654453):0.17921941,XP_040195301_1_endothelial_cell_specific_molecule_1__Rana_temporaria_:0.13902483,XP_018099979_1_endothelial_cell_specific_molecule_1__Xenopus_laevis_:0.2094915);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)