PB0165

DATABASE

Click here to access PB0165 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0165	P08697	Alpha-2-antiplasmin	SERPINF2	A2AP, AAP, ALPHA-2-PI, API, PLI, alpha2AP, serpin family F member 2	Homo_sapiens	Serine protease inhibitor. The major targets of this inhibitor are plasmin and trypsin, but it also inactivates matriptase-3/TMPRSS7 and chymotrypsin.

Domains

Gene Ontology

PF00079 (Serpin)

GO:0002020 (enables) protease binding GO:0004866 (enables) endopeptidase inhibitor activity GO:0004867 (enables) serine-type endopeptidase inhibitor activity GO:0005515 (enables) protein binding GO:0030414 (enables) peptidase inhibitor activity GO:0042803 (enables) protein homodimerization activity GO:0002034 (involved in) maintenance of blood vessel diameter homeostasis by renin-angiotensin GO:0006953 (involved in) acute-phase response GO:0010466 (involved in) negative regulation of peptidase activity GO:0010757 (involved in) negative regulation of plasminogen activation GO:0010951 (involved in) negative regulation of endopeptidase activity GO:0030199 (involved in) collagen fibril organization GO:0032967 (involved in) positive regulation of collagen biosynthetic process GO:0042730 (involved in) fibrinolysis GO:0045597 (involved in) positive regulation of cell differentiation GO:0045944 (involved in) positive regulation of transcription by RNA polymerase II GO:0046330 (involved in) positive regulation of JNK cascade GO:0048514 (involved in) blood vessel morphogenesis GO:0048661 (involved in) positive regulation of smooth muscle cell proliferation GO:0051496 (involved in) positive regulation of stress fiber assembly GO:0051918 (involved in) negative regulation of fibrinolysis GO:0070374 (involved in) positive regulation of ERK1 and ERK2 cascade GO:0071636 (involved in) positive regulation of transforming growth factor beta production GO:2000049 (involved in) positive regulation of cell-cell adhesion mediated by cadherin GO:0005576 (located in) extracellular region GO:0005615 (located in) extracellular space GO:0009986 (located in) cell surface GO:0031093 (located in) platelet alpha granule lumen GO:0070062 (located in) extracellular exosome GO:0072562 (located in) blood microparticle GO:0005577 (part of) fibrinogen complex GO:0062023 (part of) collagen-containing extracellular matrix

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|P08697|A2AP_HUMAN Alpha-2-antiplasmin OS=Homo sapiens OX=9606 GN=SERPINF2 PE=1 SV=3 MALLWGLLVLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVSPLTLLKLGNQEPGGQ TALKSPPGVCSRDPTPEQTHRLARAMMAFTADLFSLVAQTSTCPNLILSPLSVALALSHL ALGAQNHTLQRLQQVLHAGSGPCLPHLLSRLCQDLGPGAFRLAARMYLQKGFPIKEDFLE QSEQLFGAKPVSLTGKQEDDLANINQWVKEATEGKIQEFLSGLPEDTVLLLLNAIHFQGF WRNKFDPSLTQRDSFHLDEQFTVPVEMMQARTYPLRWFLLEQPEIQVAHFPFKNNMSFVV LVPTHFEWNVSQVLANLSWDTLHPPLVWERPTKVRLPKLYLKHQMDLVATLSQLGLQELF QAPDLRGISEQSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLSSFSVNRPFLFFIF EDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGPDLKLVPPM EEDYPQFGSPK >sp|P08697-2|A2AP_HUMAN Isoform 2 of Alpha-2-antiplasmin OS=Homo sapiens OX=9606 GN=SERPINF2 MALLWGLLVLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVSPLTLLKLGNQVQPGA QNHTLQRLQQVLHAGSGPCLPHLLSRLCQDLGPGAFRLAARMYLQKGFPIKEDFLEQSEQ LFGAKPVSLTGKQEDDLANINQWVKEATEGKIQEFLSGLPEDTVLLLLNAIHFQGFWRNK FDPSLTQRDSFHLDEQFTVPVEMMQARTYPLRWFLLEQPEIQVAHFPFKNNMSFVVLVPT HFEWNVSQVLANLSWDTLHPPLVWERPTKVRLPKLYLKHQMDLVATLSQLGLQELFQAPD LRGISEQSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLSSFSVNRPFLFFIFEDTT GLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGPDLKLVPPMEEDY PQFGSPK >tr|F1RAP6|F1RAP6_DANRE Serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium-derived factor), member 2b OS=Danio rerio OX=7955 GN=serpinf2b PE=3 SV=1 MNLCFLAFLLLCYSKQGWTDDVTDPEDGVDPVIPLIPLTPSKPISDLKATLDPTVTEELT VNPDGLEADPPTPGPSSGQKEGSSEEELDTLCDGDMTGKQIKRTIGNGIMKLGLLFLENL KPSPDQPNVIFSPLSLSVALSQLALGATNDTEELLLHHLHADALPCYHTALSSLLRNFRK RSMPIASRIYLKTGFKAKSDFMEDSQKLYDSEPATLTDVNDVNEWVKKVTNGHISEFLSS LPPSAVMMLINAMHYKGEWLTRFDPHFTSTENFYIDENQIVNVDMMLGPKYPLSVFTHHE LDAQVARFPFKGDRSLLVVMPTSGHVNVSAIAAKLNISDLYSRLPRERNMQVKLPKFKLD FNQDLQEAMTSMGLGKLFSHPKLDRITEVPLFVSSVQHMSSVEINEEGAEAVAATSVVIS RSNPSFTVNQPFFFALMDDLSQTPLFLGVISNPNPGASTMITNPGNADKTDDKPFEVHPK
Selected proteins from model organisms >sp|P08697|A2AP_HUMAN Alpha-2-antiplasmin OS=Homo sapiens OX=9606 GN=SERPINF2 PE=1 SV=3 MALLWGLLVLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVSPLTLLKLGNQEPGGQ TALKSPPGVCSRDPTPEQTHRLARAMMAFTADLFSLVAQTSTCPNLILSPLSVALALSHL ALGAQNHTLQRLQQVLHAGSGPCLPHLLSRLCQDLGPGAFRLAARMYLQKGFPIKEDFLE QSEQLFGAKPVSLTGKQEDDLANINQWVKEATEGKIQEFLSGLPEDTVLLLLNAIHFQGF WRNKFDPSLTQRDSFHLDEQFTVPVEMMQARTYPLRWFLLEQPEIQVAHFPFKNNMSFVV LVPTHFEWNVSQVLANLSWDTLHPPLVWERPTKVRLPKLYLKHQMDLVATLSQLGLQELF QAPDLRGISEQSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLSSFSVNRPFLFFIF EDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGPDLKLVPPM EEDYPQFGSPK >sp|P08697-2|A2AP_HUMAN Isoform 2 of Alpha-2-antiplasmin OS=Homo sapiens OX=9606 GN=SERPINF2 MALLWGLLVLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVSPLTLLKLGNQVQPGA QNHTLQRLQQVLHAGSGPCLPHLLSRLCQDLGPGAFRLAARMYLQKGFPIKEDFLEQSEQ LFGAKPVSLTGKQEDDLANINQWVKEATEGKIQEFLSGLPEDTVLLLLNAIHFQGFWRNK FDPSLTQRDSFHLDEQFTVPVEMMQARTYPLRWFLLEQPEIQVAHFPFKNNMSFVVLVPT HFEWNVSQVLANLSWDTLHPPLVWERPTKVRLPKLYLKHQMDLVATLSQLGLQELFQAPD LRGISEQSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLSSFSVNRPFLFFIFEDTT GLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGPDLKLVPPMEEDY PQFGSPK >tr|F1RAP6|F1RAP6_DANRE Serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium-derived factor), member 2b OS=Danio rerio OX=7955 GN=serpinf2b PE=3 SV=1 MNLCFLAFLLLCYSKQGWTDDVTDPEDGVDPVIPLIPLTPSKPISDLKATLDPTVTEELT VNPDGLEADPPTPGPSSGQKEGSSEEELDTLCDGDMTGKQIKRTIGNGIMKLGLLFLENL KPSPDQPNVIFSPLSLSVALSQLALGATNDTEELLLHHLHADALPCYHTALSSLLRNFRK RSMPIASRIYLKTGFKAKSDFMEDSQKLYDSEPATLTDVNDVNEWVKKVTNGHISEFLSS LPPSAVMMLINAMHYKGEWLTRFDPHFTSTENFYIDENQIVNVDMMLGPKYPLSVFTHHE LDAQVARFPFKGDRSLLVVMPTSGHVNVSAIAAKLNISDLYSRLPRERNMQVKLPKFKLD FNQDLQEAMTSMGLGKLFSHPKLDRITEVPLFVSSVQHMSSVEINEEGAEAVAATSVVIS RSNPSFTVNQPFFFALMDDLSQTPLFLGVISNPNPGASTMITNPGNADKTDDKPFEVHPK >NP_032904.1 alpha-2-antiplasmin precursor [Mus musculus] MALLRGLLVLSLSCLQGPCFTFSPVSAVDLPGQQPVSEQAQQKLPLPALFKLDNQDFGDHATLKRSPGHC KSVPTAEETRRLAQAMMAFTTDLFSLVAQTSTSSNLVLSPLSVALALSHLALGAQNQTLHSLHRVLHMNT GSCLPHLLSHFYQNLGPGTIRLAARIYLQKGFPIKDDFLEQSERLFGAKPVKLTGKQEEDLANINQWVKE ATEGKIEDFLSELPDSTVLLLLNAIHFHGFWRTKFDPSLTQKDFFHLDERFTVSVDMMHAVSYPLRWFLL EQPEIQVAHFPFKNNMSFVVVMPTYFEWNVSEVLANLTWDTLYHPSLQERPTKVWLPKLHLQQQLDLVAT LSQLGLQELFQGPDLRGISEQNLVVSSVQHQSTMELSEAGVEAAAATSVAMNRMSLSSFTVNRPFLFFIM EDTIGVPLFVGSVRNPNPSALPQLQEQRDSPDNRLIGQNDKADFHGGKTFGPDLKLAPRMEEDYPQFSSP K >NP_777095.1 alpha-2-antiplasmin precursor [Bos taurus] MALLWGLLALILSCLSSLCSAQFSPVSTMEPLDLQLMDGQAQQKLPPLSLLKLDNQEPGGQIAPKKAPED CKLSPTPEQTRRLARAMMTFTTDLFSLVAQSSTRPNLILSPLSVALALSHLALGAQNQTLQRLKEVLHAD SGPCLPHLLSRLCQDLGPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPMSLTGMKGEDLANINRWVK EATEGKIEDFLSDLPDDTVLLLLNAIHFQGFWRSKFDPNLTQRGAFHLDEQFTVPVDMMQALTYPLHWFL LEQPEIQVAHFPFKNNMSFVVLMPTRFEWNASQVLANLTWDILHQPSLSERPTKVQLPKLHLKYQLDLVA TLSQLGLQELFQAPDLRGISDERLVVSSVQHQSALELSEAGVQAAAATSTAMSRMSLSSFIVNRPFLFFI LEDSTSLPLFVGSVRNPNPGAQPERKEQQDSPDGKDSFQDHKGLPRGDKPFDPDLKLGPPSEEDYAQPSS PK >NP_001011892.1 alpha-2-antiplasmin precursor [Rattus norvegicus] MALLRGLLVLSLSCLQGPSSMFSPVSAMDLPGQQPVSEQAQQKLPPLALLKLGNQDLGDHATLKRSPGDC KSAPTTEETRRLSQAMMAFTTDLFSLVAQTSTSSNLVLSPLSVALALSHLALGARNQTLENLQRVLHMNM GSCIPHLLSHFCQNLNPGTIRLAARIYLQKGFPIKDDFLEQSEKLFGAKPVKLTGRQEEDLMNINKWVKE ATEGKIEDFLSELPDNTVLLLLNAIHFHGFWRTKFDPSLTQKDSFHLDEQFTVPVAMMHAQSYPLRWFLL EQPEIQVAHFPFQNNMSFVVIMPTYFGWNVSEVLANLTWDTLYQPSMREKPTKVRLPKLHLEQHLDLVAT LSKLGLQDLFQSPDLRGISDQSLVVSSVQHQSTMELSEAGVEAAAATSTAMTRMSLSSFFLNRPFIFFIM EETIGIPLFVGSVRNPDPSAQPQPQEQQDSPDNRRLDQNDKADIPGGKTFAPDLKLVPRLEEDYPQFSSP K >XP_016786642.1 alpha-2-antiplasmin isoform X2 [Pan troglodytes] MHVRGVRDLCHRFTRNMALLWGLLVLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVSPLTLLKLGN QEPGGQTALKSPPGVCSRDPTPEQTRRLARAMMAFTADLFSLVAQTSTCPNLILSPLSVALALSHLALGA QNHTLQRLQQVLHAGSGPCLPHLLSRLCQDLGPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLT GKQEDDLANINQWVKEATEGKIQEFLSGLPEDTVLLLLNAIHFQGFWRNKFDPSLTQRDSFHLDEQFTVP VEMMQARTYPLRWFLLEQPEIQVAHFPFKNNMSFVVLVPTHFEWNVSQVLANLSWDTLHPPLVWERPTKV RLPKLYLKHQMDLVATLSQLGLQELFQAPDLRGISEQSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRM SLSSFSVNRPFLFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGPDL KLVPPMEEDYPQFGSPK >XP_005624992.1 alpha-2-antiplasmin isoform X1 [Canis lupus familiaris] MGWLEPEQSVGSTTVGPEGHCVQQQGAYRGQQQGSPAHPTKPAETSGIHRPVYPCGQDQTKKRNMALLRG LLVISLSCLQGSGAVFPPASAMEPLDQQLMGGQTQEKLPPLTLLKLGNQESSGHIGLKKAPRDCRGAPTP EQTRRLAQAMMAFTTDLFSLVAQRSTSPNLILSPLSVALALSHLALGAQNQTLRRLEQVLHADSGPCLPH LLSRLCQDLGPGAFRLAARMYLQKGFPIKEDFLKQSEQLFGAKPMSLTGRKGDDLLNINQWVKEATEGKI EDFLSELPDDTVLLLLNAIHFQGFWRSKFDPSLTQRDSFHLNEQFTVPVDMMHARTYPLRWFLLEQPEIQ VAHFPFKNNMSFVVIMPTHFEWNVSQVLANLSWDILHQPLLREKPTKVRLPKLHLNYQLDLVATLSRLGL QELFQAPDLRGISDQRLVVTSVQHQSALELSEAGVEAAAATGTAMSRMSLSSFSVNRPFLFFILEDTTSL PLFVGSVKNPNPSAPWERKEQQDSPDDRDYFQNRKAFPRGDKPFGPDLKLAPPSEEDYPQLHSPK >XP_008268885.1 PREDICTED: alpha-2-antiplasmin isoform X1 [Oryctolagus cuniculus] MPRNMVLLRGLLVLSLSCLQGPCAVLPPVSAMEPVGRQLTSGQSQEKLPPLALLKLVNQELHGQTALKKS PGDCRETPTPEQTRRLAQAMMAFTTDLFSLVVQASTSPNLVLSPLSVALALSHLALGAQNHTLQRLQQVL HADSGPCLPHLLSHLCRNLGPGAFRLAARMYLQKGFPIKEDFLKLSEQLFGAKPVSLTGRQEEDLVNINQ WVKEATEGKIEDFLSELPDSTVLLLLNAIHFQGFWRSKFDPSLTQRDSFHLDEQFTVPVDMMQAHKYPLR WFLLEQPEIQVAQFPFKNNMSFVVLVPTNFEWNVSQVLSNLSWDILHQPSLRERPTKVQLPKLLLKHQLD LVTTLSQLGLQELFLAPDLRGISDEGLVVSSVQHQSTLELNEAGVEAAAATSTAMSRMSLSSFSVNRPFL FFILEDTIDLPIFVGIVRNPNPSAQPERKEQQDSPDHRDPSQPQKSFPHGDKLFSPDLKLAPPSEEDYPQ LSSPK >XP_002826863.1 alpha-2-antiplasmin isoform X1 [Pongo abelii] MPRNMALLWGLLVLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPTQEQVPPLTLLKLGNQEPGGRTALKSP PGVCSRDPTPEQTRRLAQAMMAFTADLFSLVAQTSTCPNLILSPLSVALALSHLALGAQNHTLQRLQQVL HAGSGPCLPHLLSRLCQNLGPGAFRLAARMYLQKGFPIKEDFLEQSQRLFGAKPVRLTGKQEDDLANINQ WVKEATEGKIQEFLSELPEDAVLLLLNAIHFQGFWRNKFDPSLTQRDSFHLDEQFTVPVEMMQARTYPLR WFLLEQPEIQVAHFPFKNNMSFVVLVPTHFEWNVSKVLANLSWDTLHPPLVWERPTKVRLPKLYLKHQMD LVATLSQLGLQELFQAPDLRGISEQSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLSSFSVNRPFL FFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGPDLKLAPPLEEDYPQ FGSPK >XP_020923238.1 alpha-2-antiplasmin [Sus scrofa] MALLSGLLVLSLFCLHVLPPVSAMDPLGLQLMIGQGQEKLSPLSLLELDNQEHGGHTALNEAPGECKGTP TPEQTRRLAQAMMAFTRDLFSLVARSSTRPNLVLSPLSVALALSHLALGAQNQTLQRLQQVLHADSGPCL PYLLSRLCQDLGPGAFRLAARMYLQKGFPIKEDFLEQSEELFGAKPMSLTGRKGDDLANINQWVKEATEG KIEDFLSDLPEDTVLLLLNAIHFQGFWRSKFDPNLTQRDTFHLDEQFTVPVDMMQARMYPLRWFLLEQPE IQVAYFPFKNNMSFVVMVPIHFEWNVSQVLANLSWDILHQPLLRERPTKVQLPKLHLKYQLDLVATLSQL GLQGLFQAPDLRGISDESLVVSSVQHQSTLELSEAGVEAAAATSTAMSRMSLSFSVNRPFLFFILEDTTS LPLFVGSVRNPNPGAQPERKEQQDSPDSRYPFWNQKAFPRGDKPFYPDLKLAPPSEEEDYPQPSGPK >XP_024997830.2 alpha-2-antiplasmin [Gallus gallus] MVLLWGLLLLSLSALHSHPRLPLAHAVEQQHLSSDKAVDLKNLKSGGDEESALPEAIPTLLDAKLADTWE TYGTTPSISTSAETEEEESPGDKATAGAVSCHEQEPSGKTLSSEEEGEGEEESCDITWKKSQKLANGLMR FSTDLLREVQQESNGNNVILSPLSIALALSNLALGAANQTEKRLLEAMHLESVPCLHHMLSSLRRRLAGA TLSLASRVYLQKGYEVKEEFLEESEKFYGAKPVTLSGSSEDDLTAINKWVKEATNGQIPTFLQQLPGDTV MLLLNAIHFHGFWRNKFDASFTAPDAFHLSDDFVVSVEMMKAQRYPLSWFTLESQDIQVAKFPFKGNMSF VVIVPNQYTWNTSHVLENFPYGQLCRLFPKEVPTTVKIPKITLDYQLELNSVLSHMGLQELFISPNLQKI SDEPLFVSSIQHQSTMELKEDGVEASAATGVMISRSLSAFSIDRPFIFILFEEEMGIPLFIGSVKNPNPN AAPQVKELQDLPDATDDNEYTMPK >XP_003816899.2 alpha-2-antiplasmin isoform X2 [Pan paniscus] MFNRMCKSIFTRRESNLNRGWLRVKVLVGGEGWAGLVGAWAESEEHPSGARGTSCVTARSPQRNMALLWG LLVLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVSPLTLLKLGNQEPGGQTALKSPPGVCSRDPTP EQTRRLARAMMAFTADLFSLVAQTSTCPNLILSPLSVALALSHLALGAQNHTLQRLQQVLHAGSGPCLPH LLSRLCQDLGPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLTGKQEDDLANINQWVKEATEGKI QEFLSGLPEDTVLLLLNAIHFQGFWRNKFDPSLTQRDSFHLDEQFTVPVEMMQARTYPLRWFLLEQPEIQ VAHFPFKNNMSFVVLVPTHFEWNVSQVLANLSWDTLHPPLVWERPTKVRLPKLYLKHQMDLVATLSQLGL QELFQAPDLRGISEQSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLSSFSVNRPFLFFIFEDTTGL PLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGPDLKLVPPMEEDYPQFGSPK >XP_006940042.1 alpha-2-antiplasmin isoform X2 [Felis catus] MGKTGKNMALLLRGLLLLGLSCLQGPCLVFSAASAMEPSDQQLMSGPAQEKLPPLILLKLGNQEPSGHIA LKKAPRDCKGAPTPEETRKLAQAMMAFTTDLFSLVAQRATSPNLILSPLSVALALSHLALGAQNQTLQKL LQVLHADSGPCLPHLLSHLCQDLGPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLTGRKRDDLV NINQWVKEATEGKIEDFLSELPDDTVLLLLNAIHFQGFWRSKFDPSLTQRDSFHLNEEFTVPVDMMQART YPLRWFLLEQPEIQVAHFPFKNNMSFVVIMPTHFEWNVSQVLANLSWDILHQPLLREKPTKVQLPKLHLK YQLDLVATLSQLGLQELFQAPDLRGISDQRLVVSSVQHQSTLELSEAGVEAAAATGTAMSRMSLSSFIVN RPFVFFILEDTTSMPLFVGSVRNPNPSAQWERKEQQDSPDDRDSFLNQKAFPRGDKPFGPDLKLAPPSEE DYPQPNSPK >XP_004012597.3 alpha-2-antiplasmin isoform X2 [Ovis aries] MALLWGLLALSLSCLPSPCSAFSPVSAMEPLGLQLMSGQAQEKLPPLSLLKLGNQEPGGQIAPKKAPGDC KASPTPEQTRRLARAMMTFTTDLFSLVAQSSTRPNLILSPLSVALALSHLALGAQNQTLQRLKQVLHADS GPCLPHLLSRLCQDLGPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPMSLTGRKGEDLANINQWVKE ATEGKIEDFLSDLPDDTVLLLLNAIHFQGFWRNKFDPNLTQRDTFHLDEQFTVPVDMMQALTYPLHWFLL EQPEIQVAHFPFKNNMSFVVLMPTRFEWNVSQVLANLTWDILHQPLLRERPTKVQLPKLHLKYQLDLVAT LSQLGLQELFQAPDLRGISDERLVVSSVQHQSALELSEAGVEAAAATSTAMSRMSLSSFVVNRPFLFFIL DDSTSLPLFVGSVRNPNPGAQPERKEQQDSPSRDSFQDHKGRPRGDKPFDPDLKLGPPSEEDYPQPSSPK >XP_018868995.1 alpha-2-antiplasmin isoform X2 [Gorilla gorilla gorilla] MPRNMALLWGLLVLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVPPLTLLKLGNQEPGGQTALKSP PGICSRDPTPEQTRRLARAMMAFTADLFSLVAQTSTCPNLILSPLSVALALSHLALGAQNHTLQRLQQVL HAGSGPCLPHLLSRLCQDLGPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLTGKQEDDLANINQ WVKEATEGKIQEFLSGLPEDTVLLLLNAIHFQGFWRNKFDPSLTQRESFHLDEQFTVPVEMMQARTYPLR WFLLEQPEIQVAHFPFKNNMSFVVLVPTHFEWNVSQVLANLSWDTLHPPLVWERPTKVRLPKLYLKHQMD LVATLSQLGLQELFQAPDLRGISEQSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLSSFSVNRPFL FFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGPDLKLVPPMEEDYPQ FGSPK >XP_004075378.1 alpha-2-antiplasmin isoform X1 [Oryzias latipes] MDICLTLLFICLCSRGVTNAEAADDDSVPVVPLIPLINSNITETDEIRGMIEPGPSIVETTVGSISGGSA SDEDDMEGCGSISQSQESLQAITAAIQKLGVQLLQNLEITPDQPNLIISPLSISLALSQLALGAENETEE LLMHHLHENSVPCYHQSLHNVLLQLRNRDLQIATGIFLGQGFEAKQEFVSESKQLYHSEPAMLENLQQIN DWVENATQGKMSDFLSSLPSNLLLMLINAVHFKGEWKARFDPRFTTRGVFHLDDMHMVDVEVMEDAKHPL SSFTDHDLGAQVAKFPFMKLMSLLVVMPLSGQVNVSSLSAKLNISDLYDRLPKERAVQVKVPKFKLEYSQ ELQEVLTRLGLGEMFQNPNLADIADGPLLVSSVKHKSIMEINEEGAEAAASTSVVISRASNPVFHLSQPF FFVLIDDMTLIPIFMGVINNPNPGGPILQRGEFGNRDKAGFPNDKNSMADFERSPK >XP_005502065.1 alpha-2-antiplasmin isoform X1 [Columba livia] MKNPRNMVFLWALVLLCLSALHSHLRFSSAHALEQKHLFLEKDGELKDVKSAGVAESAVLEAVPTLPNAD LADFTYDSFQEIDGPRFPFITPPPGMRNGRNPEDEAVAGAVGCHEQQPAGESASSEEKGEAEDESCEMTW KKSQRLAGGLMRFSINLLREAQVESNGTNVILSPLSIALALSHLALGAANQTEKHLLAAMHLQSVPCLHH VLGTLRRRFTESTLSLASRLYLQKGFEVKDKFLEDSEKFYGAKPMTLSGMGEDDLVAINTWVKEATNGQI PTFLQQLPANTVLLLLNAIHFHGVWRNKFDANFTGPDVFHLDSKFMVPVEMMKAQRYPLSWFTLESQDIQ VAKFPFQSNMSFVVIVPNQYTWNLSHVLENFPYEQLCRLFPREVPTTVKIPKIKLDYQLELNKVLSQMGL QELFTSPNLQKISDEPLFVSSVQHQSTLELKEDGVEASAATSVAVSRSVSAFSLDQPFVFIIFEDETGIP LFIGSVQNPNPNAAPQIKEPRDSHKATDVNEYPMPK >XP_005693371.2 PREDICTED: alpha-2-antiplasmin isoform X1 [Capra hircus] MALLWGLLALSLSCLPSPCSAQFSPVSAMEPLGLQLMSGQAQEKLPPLSLLKLGNQEPGGQIAPKKAPGD CKASPTPEQTRRLARAMMTFTTDLFSLVAQSSTRPNLILSPLSVALALSHLALGAQNQTLQRLKQVLHAD SGPCLPHLLSRLCQDLGPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPMSLTGRKGEDLANINQWVK EATEGKIEDFLSDLPDDTVLLLLNAIHFQGFWRNKFDPNLTQRDTFHLDEQFTVPVDMMQALTYPLHWFL LEQPEIQVAHFPFKNNMSFVVLMPTRFEWNVSQVLANLTWDILHQPLLRERPTKVQLPKLHLKYQLDLVA TLSQLGLQELFQAPDLRGISDERLVVSSVQHQSALELSEAGVEAAAATSTAMSRMSLSSFVVNRPFLFFI LEDSTSLPLFVGSVRNPNPGAQPERKEQQDSPGRDSFQDHKGRPRGDKPFDPDLKLGPPSEEDYPQPSSP K >XP_006032910.1 alpha-2-antiplasmin [Alligator sinensis] MAVLLWGLLLLCLSALHHRPWCPLAYALEMDFTPSLHQDSSQGHEATGTSGQDLQPTVTSVTLPAAVSTL PNAVVSDSTSDTWEDIHGPTLPPTPTPTTTTTTTTVCRDKFMSPEGEPVTGTVGSHEQVLEGQEVDSSEE EEERNCNISQERMRKLADGLMKFTADLLQEVERENSQPNMVLSPLSITLALSHLALGAENQTEKHLLEAM HLKSVPCLHHTLSSIRRVLTESLLSVASQLYLQKGLEVKEKFLENSERFYGAKPVTLSGNKEDDLIAINK WVQEVTKGHISSFLSQLPDSMVMLLLNAVYFRGFWRNKFDASLTGPDMFHLNDEFMVPVEMMKAPKYSLS WFTLDSLEMQVARFPFKGNMSFVAIVPNQFGWNVSEVLENVSHDKLHGRFPKEKPTLVKMPKMHVDYKLE LNEVLSRLGLKELFSAPDLRKITNEPLLVSSIQHQSTLELAEEGVEASAATSIMLSRSLSTFSLDRPFLF IIFEETTGIPLFVGKIQNPNPSAAQQRKEPEDVSDVKSGLKDSPPK >XP_006260669.2 PREDICTED: alpha-2-antiplasmin [Alligator mississippiensis] MAVLLWGLLLLCLSALHHRPWCPLAYALEMDFTPSLHQDSSQGHEATGTSGQDLQPTVTSVTLPAAVSTL SNAVVSDSTSDTWEDIHGPTLPPTPTTTTTTTTVCRDKFMSPEGEPVTGTVGSHEQVLEGQEVDSSEEEE NHEESNCNISQERMRKLADGLMKFTADLLQEVEWENSQPNMVLSPLSITLALSHLALGAENQTEKHLLEA MHLKSVPCLHHTLSSIRSVLTESMLSVASQLYLQKGLEVKEKFLENSERFYGAKPVTLSGNKEDDLIAIN KWVKEVTKGHISSFLSQLPDSMVMLLLNAVYFRGFWRNKFDASLTGPDMFHLNDEFMVPVEMMKAPKYSL SWFTLDSLEMQVARFPFKGNMSFVAIVPNQFGWNVSEVLQNVSHDKLRGRFPKEKPTLVKMPKMHVDYKL ELNEVLSRLGLKELFSAPDLRKITDEPLLVSSIQHQSTLELAEEGVEASAATSIMLSRSLSTFSLDRPFL FIIFEETMGIPLFVGKIQNPNPSAAQQRKEPEDVSDVKSGLKDSPPK >XP_015806684.1 PREDICTED: alpha-2-antiplasmin [Nothobranchius furzeri] MDLCLTLLLICLCSQGATKAEVTEDQSTPLVPLIPSQPIEEGESSTSEPLASTDVATKELAAILTSNKTS LDVNETGDCQSASQSPKSQQAIAAAVQNLGVQLLQNLETTPEHPNIIISPLSISLALSQLALGAKNETEE LLMHHLHENAVPCYHRSLRDVLAQLKKRDLQIATRIFLRQGFEAKHKFVSESQLFYGSEPAVLESLQQIN EWVENATNGRMTDFLFTLPPNLLLMLINAVHFKGEWKARFDPNFTSRGVFYLDDLHMVDVDVMEDAKHQL SCFADNELEAQVARFPFTKLMSLLVVMPESGQVNVSALCAKLNISDLYERLPKETAVQVKVPKFKLEYSQ ELQEVLTKLGLGEMFLNPNLADIADGPLLVSSVMHKSSMEINEDGAEAAAATNIVISRAAIPVFHLTKPF FFVLMDDVTQIPIFMGVINNPNPGAPILQKGQFGSKDKMGFSYDKDHMSSFGGPK >XP_020765465.1 alpha-2-antiplasmin isoform X1 [Odocoileus virginianus texanus] MALLWGLLVLSLSCLPSPCSAQFSPVSAMEPLGLQLMDGQAQKKLPPLSLLKLGNQEPGGQIAPKKAPGD CKLSPTPEQTRRLARAMMTFTTDLFSLVAQSSTRPNLILSPLSVALALSHVALGAQNQTLQRLKQVLHAD SGPCLPHLLSRLCQDLGPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGSKPMSLTGRKGEDLANINQWVK EATEGKIEDFLSDLPDDTVLLLLNAIHFQGFWRSKFDPNLTQRGTFHLDEQFTVPVDMMQALTYPLHWFL LEQPEIQVAHFPFKNNMSFVVLMPTSFEWNVSQVLANLTWDILHQPSLRERPTKVQLPKLRLKYQLDLVA TLGQLGLQELFQAPDLRGISDERLVVSSVQHQSALELSEAGVEAAAATSTAMSRMSLSSFIVNRPFLFFI LEDSMSLPLFVGSVRNPNPGAQPERKEQQDSPDGRDSFQDHKGLPRGDKPFDPDLKLGPPSEEDYPQPSS PK >XP_030249187.1 alpha-2-antiplasmin [Sparus aurata] MDFHLTLLFICLCCQGVTNAEVADNESIPLVPLIPLMPSHPIQKAENESTAQPGTTYTTEAPENVTATTN RTNGGSSEEEQDEDCLSIGRSPQSREAIAAAIQKLGVQLLQNLETSAEQPNVIISPFSISLALSQLALGA VNETQELLMHHLHENTLPCYHQSLHNVLMQLRNNDLQIATRIFLRQEFQPKQDFVDESQRLYDSEPAILE SLQQINDWVDNATNGVMTDFLSALPPNLLLMLINAVHFKGEWKARFDPRFTSRGVFYLDDKHMVDVEVME DAKHPLSLFIDNELEAQVARFPFQKLMSLLVVMPLSGQVNVSSLSAKLNVSDLYNRLPKERAVQVKVPKF KLEYAQELQDVFTKLGLGEMFSSPNLAEISDGPLLVSSVLHKSSMEINEEGAEAAAATSVVISRASSPVF HLIQPFFFALMDDMTQVPIFMGVINNPNPGAPLLQRGDQGSKDKVGFPFDKNHVGTFGGPPK >XP_040194310.1 alpha-2-antiplasmin [Rana temporaria] MLITLLCADSAGYRRIRIMGKVLFWFFLAGVCCSLAEVIDEEELPATEIETTLVSTTPLTTKATHSNIVD STSDTWSDLFPWATEFTTTSTPAIQNETEAPKYEDSIEDDQDEKISSSENACNGDFSKTEMNQFADAMMK FSTDLLKQVHLGSKSSNVVVSPLSIALGLLQLTLGAEKETEKKLLETLHVESMPCLHEKMHKVTKRLVQT ALNIASRMYVDKSFKMKEEFLVKSAKLYGSKPVNLGPDMSQNLESINKWVSDATKGKITDFLSSISEKVV LILLNAIHFKGVWKNKFDPRMTSEDTFYVNDEESMLVDMMQANKYPLRFFTSEKLDSQVAKLPFKGNMSF VIVMPHQMEWNVSNILDKLNKSELYSRLHREKPTALRVPKLNLNFKLELTNALSSLGLGQLFRKPDLGKI SDDELVVSSVEHQCTLDLNEEGVEAAAATAVVTSRSLSTFSVNRPFLFLLIDDNTGLVLFFGYVREPKPS SPRKKKDPETKFLSKGAIPK >XP_006572060.1 leukocyte elastase inhibitor [Apis mellifera] MAKANMRESFRNIRFTLTFFSVLFAPRISFVIHRMSELLHIIFIIMLGSSSATFSNNKENIGKYLSASYNNFTRDLYKEL TSTNVRNIVNSPLIIHMILSHLSHGAESTTLNELTKSLYHYNKILIEEEYKSLIIKLNELSMVKLYIANAMYIQDGFEIL TEFLTIGKDVYQSEISKVDFKNNVEASQKINAWVNEKTNNKIPYFVSSDNFNENTKLILINAIYFNGTWLNIFNIRDTKD RIFHVSKNQTKLIPTMYSKSKYTHGDMPMLQAKFIEIPYKNPDVAMIIILPNQIDGLLNLQTNFSFEMLANTTRFYNDIK LYLPKFKIEFTIDLKNALNKLGLITMFKPNANFNRISNTPLMVDKVLHKAIIDINEEGTEAAATTAVSLRLRRCIYPEET EKFIVDRPFMFILEYKPNNIPLFIGNVQDIEVISQRDEL >NP_524956.2 serpin 38F, isoform A [Drosophila melanogaster] MKYLCLLLLATSVSCRFTDDLYQLLAKENADKNLITSPLSVEIALSLAYMGARGKTAQEMRDVLKLPDDKKEVAAKFKDL LSKLEGRESVAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAISANNPKITASIVNKWVDTQTSGKIRDLVMPSDVA NLVLVILNAIYFKGQWQKKFNTEQTKSDFHISDQKSVPVQMMSLVRPFGVSYDRELGANVIELPYRNSNLSMVIFLPDKV DGLPELEKKMVGFTPKLININVHLRLPKFKIEFSARLEQVLIAMGIQDAFKTSADFNDLVANSGAHVGGVVHKAFLEVNE EGSEAAAATAVVFRYKSIRSPPMDFNVNHPFAYVIRDAENIYFQGHFVNPEL >XP_031557330.1 leukocyte elastase inhibitor-like [Actinia tenebrosa] MGNNIITCNTFRLHSVLILAVSLVFCSVLLSTMAQADLIKASTNKFSLHLHQVLRGQATFDAEQNLFYSPSSILVALAMT HLGARGNTAKQMSSSFHLDEIPEKQLNAEFQKFLQKLNQSNAKGNEIAMANRLFVQMGFEVSKQFQEDSEKFFNAEAALV DYQKNSEGARQEVNQWVEQKTKNKIKDLIPEGMFGPDTRLTLVNAIYFKGSWMSKFDSNNTQTGPFQLTPSKTVQVPMMY KSDKFKYFENEGLKCKMLELPYSDEKISMIILLPDEVDGLSKLEDSLNYSKLDEAIGHLKMAPKEEVEVTLPKFKLSEKF SLKEVLSKMGASDLFNAAKADLTGINKDGQLYVSEVVHKAFVDVNEEGTEAAAATAVRVALMCMPMNPIFFANHPFLFLI RHNESGAILFIGRLANPK >XP_038050239.1 leukocyte elastase inhibitor-like [Patiria miniata] MYKLTLLVTSSRPDSIMAVIQIISILTVIALLYMSVFATSTGPDPQLELADANNRFAFHLYQTLADDPHRDNIFFSPMSI SIALAMTSLGARGNTARQIKDVLKFSTLEESRLHSSFAELNSAIFGANADKYVLRKANRLFGHKGFDLRQEFLADAERYY SSHMASLDFVEDTEVAREFINSWVGRETEDKIRDLLPHGSITGMTQLVLVNAIYFKADWVRQFDKSKTFDQDFHVSKDQV LEVPMMHRKSKFNFAEDITLRCKLIELPYVGQDFSMIVVLPDEIDGIDRLQKHLTNEKLQHLLNNLSNVTVGVAIPKFKL EETLHMNDVLYSMGMRDLFVRDKADLSGITGTRDLFVSSVIHRAFLEVNEEGSEAAAATAVTINKRSISLAPEFIADHPF LFFIADSKTKAIVFMGHCRKPEGVSLNHEEL >XP_039269246.1 serpin B9-like [Styela clava] MIKMKNIIISLGIAICLAVMSKADKMKTSTTPSDECSMASGAEANRIFAYEMYKVAAKLKPNQNIFLAPTTVGSGLSMML PGARESTKDQMLEGLMFKNTSTGFEPNDIECLMKMYSNELIETKLEDRGKGTKDVKAAKEDTLQLRTANRLFGEKSFNFS SKFIEQTAKYGVEMTKMNFQTDSAESRNFINQWVEKATEGKIKDLFSGKAIRPDTVLAVVSAIYFKGLWKYPFDPLNTFK QDFKVNDNKTVKADFMTKMINYRMTYSEDLEAQILDVPYDGDAYGKYNASMILIVPTRRGSIERVEEMLSEKTMKPILDE LQAEQQYTQRVRLLLPKFKMSKTYQLKPILRRLGIKNLFNPIRANLSGMIDPSEISPNLYVSTAVHKTFIKVDEKGTEAA GASGFGIVPLSLPPRLFCNRPFLFMIYEKNTDGVLFIGKVNDPTVQ >NP_001122924.1 SERPIN domain-containing protein [Caenorhabditis elegans] MSDPKENMALLLQSETDFGLGLLRQQNISESLAFSPLSIALALSLVHVAAKGETRDQIREALVKGSTDEQLEQHFANISA ALLAAERGTEVKLANHVFTRAGFKIKQSYLDDVKKLYNAGASSLDFDNKEATAEAINNFVRENTGDHIKKIIGSDSINSD LVAVLTNALYFKADWQNKFKKDSTFKSEFFSSADSKREIDFLHASSVSRDYAENDQFQVLSLPYKDNTFALTIFLPKTRF GLTESLKTLDSATIQHLLSNVSSTSVNVQIPKWKIETKLGLEEALQSLGIKKAFDNDADLGNMADGLYVSKVTHKALIEV DEEGTKAAAATTVSISLKSAMFVMEEPKDFTADHPFFFVLSKDNHPLFVGLHH >XP_030848953.1 leukocyte elastase inhibitor-like [Strongylocentrotus purpuratus] MAFSKQQDTSGQLVQLSSANIGFALDLYQTLQDERRGTNLFFSPLSISTALAMTQLGARGDTATQIADVFRFNQVDQDQL HGTFKELNNLLYQTDSGYKLHSANRLYGKSGYNFVQSFLEGTVFYYGAAIEAVNDFASPIATQSINDWVSKQTEGKIKNL IAPGTLNDLTRLVLVNAIYFKANWKSKFYAENTTHDTCTFKVFDERYKVPVSLMSQKGRFALTVDNTNDCLVLELPYESH NLSLLIALPTKDDGLGQLETKLSVDVLQSWDVGLKSRRVNVLLPKFKLEATFQLKEVLKRMGMPDAFDEDRANFKGISSE EREFYISAVIHKAFINVNEEGSEAAAATAFVMAGGGPRIEREKPILFRADHPFLFMIRHRSTKSVLFMGRMMDPS >XP_043759289.1 alpha-2-antiplasmin isoform X2 [Cervus elaphus] MALLWGLLVLSLSCLPSPCSAFSPVSAMEPLGLQLMGGQAQEKLPPLSLLKLGNQEPGGQIAPKKAPGECKASPTPEQTR RLAQAMMTFTTDLFSLVAQSSTRPNLILSPLSVALALSHVALGAQNQTLQRLKQVLHADSGPCLPHLLSHLCQELGPGAF RLAARMYLQKGFPIKEDFLEQSEQLFGSKPMSLTGRKGEDLANINQWVKEATEGKIEDFLSDLPDDTVLLLLNAIHFQGF WRSKFDPNLTQRGTFHLDEQFTVPVDMMQALTYPLHWFLLEQPEIQVAHFPFKNNMSFVVLMPTSFEWNVSQVLANLTWD ILHQPSLRERPTKVQLPKLRLKYQLDLVATLSQLGLQELFQAPDLRGISDERLVVSSVQHQSALELSEAGVEAAAATSTA MSRMSLSSFIVNRPFLFFILEDSMSLPLFVGSVRNPNPGAQPERKEQQDSPDGRDSFQDHKGLPRGDKPFDPDLKLGPPS EEDYPQPSSPK >KAB0367107.1 hypothetical protein FD755_020431 [Muntiacus reevesi] MALLWGLLVLSLSCLPSPCSAQFSPVSAMEPLGLQLMGGQAQEKLPPLSLLKLGNQEPGSQIAPKKAPGDCKASPTPEQT RRLAQAMVTFTTDLFSLVAQSSTRPNLILSPLSVALALSHVALGAQNQTLQRLKQVLHADSGPCLPHLLSRLCQDLGPGA FRLAARMYLQKGFPIKEDFLEQSEQLFGSKPMSLTGRKGEDLANINQWVKEATEGKIEDFLSDLPDDTVLLLLNAIHFQG FWRSKFDPNLTQRGTFHLDEQFTVPVDMMQALTYPLHWFLLEQPEIQVAHFPFKNNMSFVVLMPTSFEWNVSQVLANLTW DILHQPSLRERPTKVQLPKLRLKYQLDLVATLSQLGLQELFQAPDLRGISDERLVVSSVQHQSALELSEAGVEAAAATST AMSRMSLSSFIVNRPFLFFILEDSTSLPLFVGSVRNPNPGAQPERKEQQDSPDGRDSFQDHKGLPRGDKPFDPDLKLGPP SEEDYPQPSSPK >KAB0366160.1 hypothetical protein FD754_010316 [Muntiacus muntjak] MALLWGLLVLSLSCLPSPCSAQFSPVSAMEPLGLQLMGGQAQEKLPPLSLLKLGNQEPGSQIAPKKAPGDCKSSPTPEQT RRLAQAMVTFTTDLFSLVAQSSTRPNLILSPLSVALALSHVALGAQNQTLQRLKQVLHADSGPCLPHLLSRLCQDLGPGA FRLAARMYLQKGFPIKEDFLEQSEQLFGSKPMSLTGRKGEDLANINQWVKEATEGKIEDFLSDLPDDTVLLLLNAIHFQG FWRSKFDPNLTQRGTFHLDEQFTVPVDMMQALTYPLHWFLLEQPEIQVAHFPFKNNMSFVVLMPTSFEWNVSQVLANLTW DILHQPSLRERPTKVQLPKLRLKYQLDLVATLSQLGLQELFQAPDLRGISDERLVVSSVQHQSALELSEAGVEAAAATST AMSRMSLSSFIVNRPFLFFILEDSTSLPLFVGSVRNPNPGAQPERKEQQDSPDGRDSFQDHKGLPRGDKPFDPDLKLGPP SEEDYPQPSSPK >XP_043334282.1 alpha-2-antiplasmin isoform X2 [Cervus canadensis] MALLWGLLVLSLSCLPSPCSAFSPVSAMEPLGLQLMGGQAQEKLPPLSLLKLGNQEPGGQIAPKKAPGECKASPTPEQTR RLAQAMMTFTTDLFSLVAQSSTRPNLILSPLSVALALSHVALGAQNQTLQRLKQVLHADSGPCLPHLLSHLCQELGPGAF RLAARMYLQKGFPIKEDFLEQSEQLFRSKPMSLTGRKGEDLANINQWVKEATEGKIEDFLSDLPDDTVLLLLNAIHFQGF WRSKFDPNLTQRGTFHLDEQFTVPVDMMQALTYPLHWFLLEQPEIQVAHFPFKNNMSFVVLMPTSFEWNVSQVLANLTWD ILHQPSLRERPTKVQLPKLRLKYQLDLVATLSQLGLQELFQAPDLRGISDERLVVSSVQHQSALELSEAGVEAAAATSTA MSRMSLSSFIVNRPFLFFILEDSMSLPLFVGSVRNPNPGAQPERKEQQDSPDGRDSFQDHKGLPRGDKPFDPDLKLGPPS EEDYPQPSSPK >KAF4012197.1 hypothetical protein G4228_003071 [Cervus hanglu yarkandensis] MALLWGLLVLSLSCLPSPCSAQFSPVSAMEPLGLQEPGGQIAPKKAPGECKASPTPEQTRRLAQAMMTFTTDLFSLVAQS STRPNLILSPLSVALALSHVALGAQNQTLQRLKQVLHADSGPCLPHLLSHLCQELGPGAFRLAARMYLQKGFPIKEDFLE QSEQLFGSKPMSLTGRKGEDLANINQWVKEATEGKIEDFLSDLPDDTVLLLLNAIHFQGFWRSKFDPNLTQRGTFHLDEQ FTVPVDMMQALTYPLHWFLLEQPEIQVAHFPFKNNMSFVVLMPTSFEWNVSQVLANLTWDILHQPSLRERPTKVQLPKLR LKYQLDLVATLSQLGLQELFQAPDLRGISDERLVVSSVQHQSALELSEAGVEAAAATSTAMSRMSLSSFIVNRPFLFFIL EDSMSLPLFVGSVRNPNPGAQPERKEQQDSPDGRDSFQDHKGLPRGDKPFDPDLKLGPPSEEDYPQPSSPK >XP_018101643.1 alpha-2-antiplasmin isoform X4 [Xenopus laevis] MERLLLLCLIVLSGINGSSAYTTEVPPDANIEDKNVTTQHYETTSIPEDSTSDTWEDLHPLVTTACRTIDFETTTASDSD NLGSEDKLEEGSDDKLEEGSDDKLEEGSDDKLEEGPEDKLEEEPEDKLEEGPEDKLEEDPLKKLEEGADEKHPSEDNEPC KLVMDDNDDDNEVEQESCDENASLEEMRKFSQAITSFSIDLLKEIDPESQKPSAVMSPFSIALGLLQLSLGAGKEMQDKL METLHVESLHCLHNKLKTVRKELTTSILRTATRIYLKKGFQIKKSFLKRSEKWYGSKPMNLASKKKQNLDSINKWVKDVT EGQIPHFLSDLPQNVALILLNAMHFKGIWKNTFDPSLTSEEIFYINDDVGVPVEMMSAQKYPFSWFYLDGIEGHVAKLQF KGNMSFVILMPFSSTWNLSKLLANFNQSDLYSRFPKEKASNLKMPKLNLDYKLELNEALTNLGLGQLFTNPDLSGITNEP LFVSSIQHQSSLELNEEGVEASAATAVMTSRSHSVFRINRPFIFFLFEDTMGLPLFMGQVRDPSSGYQKKSSSKDKKNFN NGFLPK
Mafft alignment of selected proteins >sp|P08697|A2AP_HUMAN Alpha-2-antiplasmin OS=Homo sapiens OX=9606 GN=SERPINF2 PE=1 SV=3 ------------------------------------------------------------ ----------------------MALL-WGLL---------------VLSWSCLQGPCSV- FSPVSAMEPL-----------GRQLTSGPNQ------------EQVSPLTLLKLGN---- ------------------------------------------------------------ ------------------------------------QEPGGQTA-LKSPPG--------- ----------VCSRDPTPEQTHRLARAMMAFTADLFSLVAQT---STCPNLILSPLSVAL ALSHLALGAQNHTLQRLQQVLHAGS---------GPCLPHLLSRLCQDLG---------- -------PGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLT--GKQEDDLANINQW VKEATEGKIQEFLS--GLPEDTVLLLLNAIHFQGFWRNKFDPSLTQRD--SFHLDEQF-T VPVEMMQARTYPLRWFLLEQPEIQVAHFPFKN------NMSFVVLVPTHFEWNVSQVLAN LSWDTLHPPLVWER-------PTKVRLPKLYLKHQMDLVATLSQLGLQELFQA--PDLRG ISE-----QSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLS-------SFSVNRPF LFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGPDLK LVPPM-EEDYPQFGSPK >sp|P08697-2|A2AP_HUMAN Isoform 2 of Alpha-2-antiplasmin OS=Homo sapiens OX=9606 GN=SERPINF2 ------------------------------------------------------------ ----------------------MALL-WGLL---------------VLSWSCLQGPCSV- FSPVSAMEPL-----------GRQLTSGPNQ------------EQVSPLTLLKLGN---- ------------------------------------------------------------ ------------------------------------Q----------------------- ------------------------------------------------------------ ----VQPGAQNHTLQRLQQVLHAGS---------GPCLPHLLSRLCQDLG---------- -------PGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLT--GKQEDDLANINQW VKEATEGKIQEFLS--GLPEDTVLLLLNAIHFQGFWRNKFDPSLTQRD--SFHLDEQF-T VPVEMMQARTYPLRWFLLEQPEIQVAHFPFKN------NMSFVVLVPTHFEWNVSQVLAN LSWDTLHPPLVWER-------PTKVRLPKLYLKHQMDLVATLSQLGLQELFQA--PDLRG ISE-----QSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLS-------SFSVNRPF LFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGPDLK LVPPM-EEDYPQFGSPK >tr|F1RAP6|F1RAP6_DANRE Serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium-derived factor), member 2b OS=Danio rerio OX=7955 GN=serpinf2b PE=3 SV=1 ------------------------------------------------------------ ----------------------MNLCFLAFL---------------LLCYSKQG------ WTD-DVTDPED--------------------------------GVDPVIPLIPLTPSKPI SDLKATLD----PTVTEEL-------------TVNPDGLEADP----------------- ---------------------------------PTPGPSSGQKEGSSEEELD-------- --------TLCDGDMTGKQIKRTIGNGIMKLGLLFLENLKPS---PDQPNVIFSPLSLSV ALSQLALGATNDTEELLLHHLHADA---------LPCYHTALSSLLRNFR---------- -------KRSMPIASRIYLKTGFKAKSDFMEDSQKLYDSEPATLT-------DVNDVNEW VKKVTNGHISEFLS--SLPPSAVMMLINAMHYKGEWLTRFDPHFTSTE--NFYIDENQ-I VNVDMMLGPKYPLSVFTHHELDAQVARFPFKG------DRSLLVVMPTSGHVNVSAIAAK LNISDLYSRLPRER-------NMQVKLPKFKLDFNQDLQEAMTSMGLGKLFSH--PKLDR ITE-----VPLFVSSVQHMSSVEINEEGAEAVAATSVVISR-SNP-------SFTVNQPF FFALMDDLSQTPLFLGVISNPNPGASTMITNPGNADKTDDKPFE---------------- -------------VHPK >NP_032904.1 alpha-2-antiplasmin precursor [Mus musculus] ------------------------------------------------------------ ----------------------MALL-RGLL---------------VLSLSCLQGPCFT- FSPVSAVDLP-----------GQQPVSEQAQ------------QKLPLPALFKLDN---- ------------------------------------------------------------ ------------------------------------QDFGDHAT-LKRSPG--------- ----------HCKSVPTAEETRRLAQAMMAFTTDLFSLVAQT---STSSNLVLSPLSVAL ALSHLALGAQNQTLHSLHRVLHMNT---------GSCLPHLLSHFYQNLG---------- -------PGTIRLAARIYLQKGFPIKDDFLEQSERLFGAKPVKLT--GKQEEDLANINQW VKEATEGKIEDFLS--ELPDSTVLLLLNAIHFHGFWRTKFDPSLTQKD--FFHLDERF-T VSVDMMHAVSYPLRWFLLEQPEIQVAHFPFKN------NMSFVVVMPTYFEWNVSEVLAN LTWDTLYHPSLQER-------PTKVWLPKLHLQQQLDLVATLSQLGLQELFQG--PDLRG ISE-----QNLVVSSVQHQSTMELSEAGVEAAAATSVAMNRMSLS-------SFTVNRPF LFFIMEDTIGVPLFVGSVRNPNPSALPQLQEQRDSPDNRLIGQNDKADFHGGKTFGPDLK LAPRM-EEDYPQFSSPK >NP_777095.1 alpha-2-antiplasmin precursor [Bos taurus] ------------------------------------------------------------ ----------------------MALL-WGLL---------------ALILSCLSSLCSAQ FSPVSTMEPL-----------DLQLMDGQAQ------------QKLPPLSLLKLDN---- ------------------------------------------------------------ ------------------------------------QEPGGQIA-PKKAPE--------- ----------DCKLSPTPEQTRRLARAMMTFTTDLFSLVAQS---STRPNLILSPLSVAL ALSHLALGAQNQTLQRLKEVLHADS---------GPCLPHLLSRLCQDLG---------- -------PGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPMSLT--GMKGEDLANINRW VKEATEGKIEDFLS--DLPDDTVLLLLNAIHFQGFWRSKFDPNLTQRG--AFHLDEQF-T VPVDMMQALTYPLHWFLLEQPEIQVAHFPFKN------NMSFVVLMPTRFEWNASQVLAN LTWDILHQPSLSER-------PTKVQLPKLHLKYQLDLVATLSQLGLQELFQA--PDLRG ISD-----ERLVVSSVQHQSALELSEAGVQAAAATSTAMSRMSLS-------SFIVNRPF LFFILEDSTSLPLFVGSVRNPNPGAQPERKEQQDSPDGKDSFQDHKGLPRGDKPFDPDLK LGPPS-EEDYAQPSSPK >NP_001011892.1 alpha-2-antiplasmin precursor [Rattus norvegicus] ------------------------------------------------------------ ----------------------MALL-RGLL---------------VLSLSCLQGPSSM- FSPVSAMDLP-----------GQQPVSEQAQ------------QKLPPLALLKLGN---- ------------------------------------------------------------ ------------------------------------QDLGDHAT-LKRSPG--------- ----------DCKSAPTTEETRRLSQAMMAFTTDLFSLVAQT---STSSNLVLSPLSVAL ALSHLALGARNQTLENLQRVLHMNM---------GSCIPHLLSHFCQNLN---------- -------PGTIRLAARIYLQKGFPIKDDFLEQSEKLFGAKPVKLT--GRQEEDLMNINKW VKEATEGKIEDFLS--ELPDNTVLLLLNAIHFHGFWRTKFDPSLTQKD--SFHLDEQF-T VPVAMMHAQSYPLRWFLLEQPEIQVAHFPFQN------NMSFVVIMPTYFGWNVSEVLAN LTWDTLYQPSMREK-------PTKVRLPKLHLEQHLDLVATLSKLGLQDLFQS--PDLRG ISD-----QSLVVSSVQHQSTMELSEAGVEAAAATSTAMTRMSLS-------SFFLNRPF IFFIMEETIGIPLFVGSVRNPDPSAQPQPQEQQDSPDNRRLDQNDKADIPGGKTFAPDLK LVPRL-EEDYPQFSSPK >XP_016786642.1 alpha-2-antiplasmin isoform X2 [Pan troglodytes] M------------------------------------------------------HVRGV RDL---------C---HRFTRNMALL-WGLL---------------VLSWSCLQGPCSV- FSPVSAMEPL-----------GRQLTSGPNQ------------EQVSPLTLLKLGN---- ------------------------------------------------------------ ------------------------------------QEPGGQTA-LKSPPG--------- ----------VCSRDPTPEQTRRLARAMMAFTADLFSLVAQT---STCPNLILSPLSVAL ALSHLALGAQNHTLQRLQQVLHAGS---------GPCLPHLLSRLCQDLG---------- -------PGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLT--GKQEDDLANINQW VKEATEGKIQEFLS--GLPEDTVLLLLNAIHFQGFWRNKFDPSLTQRD--SFHLDEQF-T VPVEMMQARTYPLRWFLLEQPEIQVAHFPFKN------NMSFVVLVPTHFEWNVSQVLAN LSWDTLHPPLVWER-------PTKVRLPKLYLKHQMDLVATLSQLGLQELFQA--PDLRG ISE-----QSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLS-------SFSVNRPF LFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGPDLK LVPPM-EEDYPQFGSPK >XP_005624992.1 alpha-2-antiplasmin isoform X1 [Canis lupus familiaris] ------------------MGWLEPEQSVGSTTVGPEGHCVQQQGAYRGQQQGSPAHPTKP AETSGIHRPVYPCGQDQTKKRNMALL-RGLL---------------VISLSCLQGSGAV- FPPASAMEPL-----------DQQLMGGQTQ------------EKLPPLTLLKLGN---- ------------------------------------------------------------ ------------------------------------QESSGHIG-LKKAPR--------- ----------DCRGAPTPEQTRRLAQAMMAFTTDLFSLVAQR---STSPNLILSPLSVAL ALSHLALGAQNQTLRRLEQVLHADS---------GPCLPHLLSRLCQDLG---------- -------PGAFRLAARMYLQKGFPIKEDFLKQSEQLFGAKPMSLT--GRKGDDLLNINQW VKEATEGKIEDFLS--ELPDDTVLLLLNAIHFQGFWRSKFDPSLTQRD--SFHLNEQF-T VPVDMMHARTYPLRWFLLEQPEIQVAHFPFKN------NMSFVVIMPTHFEWNVSQVLAN LSWDILHQPLLREK-------PTKVRLPKLHLNYQLDLVATLSRLGLQELFQA--PDLRG ISD-----QRLVVTSVQHQSALELSEAGVEAAAATGTAMSRMSLS-------SFSVNRPF LFFILEDTTSLPLFVGSVKNPNPSAPWERKEQQDSPDDRDYFQNRKAFPRGDKPFGPDLK LAPPS-EEDYPQLHSPK >XP_008268885.1 PREDICTED: alpha-2-antiplasmin isoform X1 [Oryctolagus cuniculus] ------------------------------------------------------------ ------------------MPRNMVLL-RGLL---------------VLSLSCLQGPCAV- LPPVSAMEPV-----------GRQLTSGQSQ------------EKLPPLALLKLVN---- ------------------------------------------------------------ ------------------------------------QELHGQTA-LKKSPG--------- ----------DCRETPTPEQTRRLAQAMMAFTTDLFSLVVQA---STSPNLVLSPLSVAL ALSHLALGAQNHTLQRLQQVLHADS---------GPCLPHLLSHLCRNLG---------- -------PGAFRLAARMYLQKGFPIKEDFLKLSEQLFGAKPVSLT--GRQEEDLVNINQW VKEATEGKIEDFLS--ELPDSTVLLLLNAIHFQGFWRSKFDPSLTQRD--SFHLDEQF-T VPVDMMQAHKYPLRWFLLEQPEIQVAQFPFKN------NMSFVVLVPTNFEWNVSQVLSN LSWDILHQPSLRER-------PTKVQLPKLLLKHQLDLVTTLSQLGLQELFLA--PDLRG ISD-----EGLVVSSVQHQSTLELNEAGVEAAAATSTAMSRMSLS-------SFSVNRPF LFFILEDTIDLPIFVGIVRNPNPSAQPERKEQQDSPDHRDPSQPQKSFPHGDKLFSPDLK LAPPS-EEDYPQLSSPK >XP_002826863.1 alpha-2-antiplasmin isoform X1 [Pongo abelii] ------------------------------------------------------------ ------------------MPRNMALL-WGLL---------------VLSWSCLQGPCSV- FSPVSAMEPL-----------GRQLTSGPTQ------------EQVPPLTLLKLGN---- ------------------------------------------------------------ ------------------------------------QEPGGRTA-LKSPPG--------- ----------VCSRDPTPEQTRRLAQAMMAFTADLFSLVAQT---STCPNLILSPLSVAL ALSHLALGAQNHTLQRLQQVLHAGS---------GPCLPHLLSRLCQNLG---------- -------PGAFRLAARMYLQKGFPIKEDFLEQSQRLFGAKPVRLT--GKQEDDLANINQW VKEATEGKIQEFLS--ELPEDAVLLLLNAIHFQGFWRNKFDPSLTQRD--SFHLDEQF-T VPVEMMQARTYPLRWFLLEQPEIQVAHFPFKN------NMSFVVLVPTHFEWNVSKVLAN LSWDTLHPPLVWER-------PTKVRLPKLYLKHQMDLVATLSQLGLQELFQA--PDLRG ISE-----QSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLS-------SFSVNRPF LFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGPDLK LAPPL-EEDYPQFGSPK >XP_020923238.1 alpha-2-antiplasmin [Sus scrofa] ------------------------------------------------------------ ----------------------MALL-SGLL---------------VLSLFCLH----V- LPPVSAMDPL-----------GLQLMIGQGQ------------EKLSPLSLLELDN---- ------------------------------------------------------------ ------------------------------------QEHGGHTA-LNEAPG--------- ----------ECKGTPTPEQTRRLAQAMMAFTRDLFSLVARS---STRPNLVLSPLSVAL ALSHLALGAQNQTLQRLQQVLHADS---------GPCLPYLLSRLCQDLG---------- -------PGAFRLAARMYLQKGFPIKEDFLEQSEELFGAKPMSLT--GRKGDDLANINQW VKEATEGKIEDFLS--DLPEDTVLLLLNAIHFQGFWRSKFDPNLTQRD--TFHLDEQF-T VPVDMMQARMYPLRWFLLEQPEIQVAYFPFKN------NMSFVVMVPIHFEWNVSQVLAN LSWDILHQPLLRER-------PTKVQLPKLHLKYQLDLVATLSQLGLQGLFQA--PDLRG ISD-----ESLVVSSVQHQSTLELSEAGVEAAAATSTAMSRMSL--------SFSVNRPF LFFILEDTTSLPLFVGSVRNPNPGAQPERKEQQDSPDSRYPFWNQKAFPRGDKPFYPDLK LAPPSEEEDYPQPSGPK >XP_024997830.2 alpha-2-antiplasmin [Gallus gallus] ------------------------------------------------------------ ----------------------MVLL-WGLL---------------LLSLSALHSHPR-- LPLAHAVEQQH---LSSDKAVDLKNLKSGGDE------ESALPEAIPTLLDAKLAD-T-- WETYGTT-----PSISTSAE------------TEEEESPGDKA----------------- ---------------------TAGAVS------CHEQEPSGKTL-SSEEEGE-------- --------GEEESCDITWKKSQKLANGLMRFSTDLLREVQQE---SNGNNVILSPLSIAL ALSNLALGAANQTEKRLLEAMHLES---------VPCLHHMLSSLRRRLA---------- -------GATLSLASRVYLQKGYEVKEEFLEESEKFYGAKPVTLS--GSSEDDLTAINKW VKEATNGQIPTFLQ--QLPGDTVMLLLNAIHFHGFWRNKFDASFTAPD--AFHLSDDF-V VSVEMMKAQRYPLSWFTLESQDIQVAKFPFKG------NMSFVVIVPNQYTWNTSHVLEN FPYGQLCRLFPKEV-------PTTVKIPKITLDYQLELNSVLSHMGLQELFIS--PNLQK ISD-----EPLFVSSIQHQSTMELKEDGVEASAATGVMISR-SLS-------AFSIDRPF IFILFEEEMGIPLFIGSVKNPNPNAAPQVKELQDLPDATDDNEY---------------- -------------TMPK >XP_003816899.2 alpha-2-antiplasmin isoform X2 [Pan paniscus] MFNRMCKSIFTRRESNLNRGWLRVKVLVGG----------EGWAGLVGAWAESEEHPSGA RGTS--------CVTARSPQRNMALL-WGLL---------------VLSWSCLQGPCSV- FSPVSAMEPL-----------GRQLTSGPNQ------------EQVSPLTLLKLGN---- ------------------------------------------------------------ ------------------------------------QEPGGQTA-LKSPPG--------- ----------VCSRDPTPEQTRRLARAMMAFTADLFSLVAQT---STCPNLILSPLSVAL ALSHLALGAQNHTLQRLQQVLHAGS---------GPCLPHLLSRLCQDLG---------- -------PGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLT--GKQEDDLANINQW VKEATEGKIQEFLS--GLPEDTVLLLLNAIHFQGFWRNKFDPSLTQRD--SFHLDEQF-T VPVEMMQARTYPLRWFLLEQPEIQVAHFPFKN------NMSFVVLVPTHFEWNVSQVLAN LSWDTLHPPLVWER-------PTKVRLPKLYLKHQMDLVATLSQLGLQELFQA--PDLRG ISE-----QSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLS-------SFSVNRPF LFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGPDLK LVPPM-EEDYPQFGSPK >XP_006940042.1 alpha-2-antiplasmin isoform X2 [Felis catus] ------------------MG---------------------------------------- ----------------KTGKNMALLL-RGLL---------------LLGLSCLQGPCLV- FSAASAMEPS-----------DQQLMSGPAQ------------EKLPPLILLKLGN---- ------------------------------------------------------------ ------------------------------------QEPSGHIA-LKKAPR--------- ----------DCKGAPTPEETRKLAQAMMAFTTDLFSLVAQR---ATSPNLILSPLSVAL ALSHLALGAQNQTLQKLLQVLHADS---------GPCLPHLLSHLCQDLG---------- -------PGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLT--GRKRDDLVNINQW VKEATEGKIEDFLS--ELPDDTVLLLLNAIHFQGFWRSKFDPSLTQRD--SFHLNEEF-T VPVDMMQARTYPLRWFLLEQPEIQVAHFPFKN------NMSFVVIMPTHFEWNVSQVLAN LSWDILHQPLLREK-------PTKVQLPKLHLKYQLDLVATLSQLGLQELFQA--PDLRG ISD-----QRLVVSSVQHQSTLELSEAGVEAAAATGTAMSRMSLS-------SFIVNRPF VFFILEDTTSMPLFVGSVRNPNPSAQWERKEQQDSPDDRDSFLNQKAFPRGDKPFGPDLK LAPPS-EEDYPQPNSPK >XP_004012597.3 alpha-2-antiplasmin isoform X2 [Ovis aries] ------------------------------------------------------------ ----------------------MALL-WGLL---------------ALSLSCLPSPCSA- FSPVSAMEPL-----------GLQLMSGQAQ------------EKLPPLSLLKLGN---- ------------------------------------------------------------ ------------------------------------QEPGGQIA-PKKAPG--------- ----------DCKASPTPEQTRRLARAMMTFTTDLFSLVAQS---STRPNLILSPLSVAL ALSHLALGAQNQTLQRLKQVLHADS---------GPCLPHLLSRLCQDLG---------- -------PGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPMSLT--GRKGEDLANINQW VKEATEGKIEDFLS--DLPDDTVLLLLNAIHFQGFWRNKFDPNLTQRD--TFHLDEQF-T VPVDMMQALTYPLHWFLLEQPEIQVAHFPFKN------NMSFVVLMPTRFEWNVSQVLAN LTWDILHQPLLRER-------PTKVQLPKLHLKYQLDLVATLSQLGLQELFQA--PDLRG ISD-----ERLVVSSVQHQSALELSEAGVEAAAATSTAMSRMSLS-------SFVVNRPF LFFILDDSTSLPLFVGSVRNPNPGAQPERKEQQDSPS-RDSFQDHKGRPRGDKPFDPDLK LGPPS-EEDYPQPSSPK >XP_018868995.1 alpha-2-antiplasmin isoform X2 [Gorilla gorilla gorilla] ------------------------------------------------------------ ------------------MPRNMALL-WGLL---------------VLSWSCLQGPCSV- FSPVSAMEPL-----------GRQLTSGPNQ------------EQVPPLTLLKLGN---- ------------------------------------------------------------ ------------------------------------QEPGGQTA-LKSPPG--------- ----------ICSRDPTPEQTRRLARAMMAFTADLFSLVAQT---STCPNLILSPLSVAL ALSHLALGAQNHTLQRLQQVLHAGS---------GPCLPHLLSRLCQDLG---------- -------PGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLT--GKQEDDLANINQW VKEATEGKIQEFLS--GLPEDTVLLLLNAIHFQGFWRNKFDPSLTQRE--SFHLDEQF-T VPVEMMQARTYPLRWFLLEQPEIQVAHFPFKN------NMSFVVLVPTHFEWNVSQVLAN LSWDTLHPPLVWER-------PTKVRLPKLYLKHQMDLVATLSQLGLQELFQA--PDLRG ISE-----QSLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLS-------SFSVNRPF LFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDFLQSLKGFPRGDKLFGPDLK LVPPM-EEDYPQFGSPK >XP_004075378.1 alpha-2-antiplasmin isoform X1 [Oryzias latipes] ------------------------------------------------------------ ----------------------MDIC-LTLL---------------FICLCSRG------ VTNAEAADD----------------------------------DSVPVVPLIPLINSN-- ITETDEIR----GMIEPG--------------------PSIVE----------------- ---------------------------------TTVGSISGG---SASDEDD-------- -------MEGCGSISQSQESLQAITAAIQKLGVQLLQNLEIT---PDQPNLIISPLSISL ALSQLALGAENETEELLMHHLHENS---------VPCYHQSLHNVLLQLR---------- -------NRDLQIATGIFLGQGFEAKQEFVSESKQLYHSEPAMLE-------NLQQINDW VENATQGKMSDFLS--SLPSNLLLMLINAVHFKGEWKARFDPRFTTRG--VFHLDDMH-M VDVEVMEDAKHPLSSFTDHDLGAQVAKFPFMK------LMSLLVVMPLSGQVNVSSLSAK LNISDLYDRLPKER-------AVQVKVPKFKLEYSQELQEVLTRLGLGEMFQN--PNLAD IAD-----GPLLVSSVKHKSIMEINEEGAEAAASTSVVISRASNP-------VFHLSQPF FFVLIDDMTLIPIFMGVINNPNPGGPILQRGEFGNRDKAGFPNDKNSM----ADFE---- -------------RSPK >XP_005502065.1 alpha-2-antiplasmin isoform X1 [Columba livia] ------------------MK---------------------------------------- ------------------NPRNMVFL-WALV---------------LLCLSALHSHLR-- FSSAHALEQKH---LFLEKDGELKDVKSAGVA------ESAVLEAVPTLPNADLADFT-- YDSFQEIDGPRFPFITPPPG------------MRNGRNPEDEA----------------- ---------------------VAGAVG------CHEQQPAGESA-SSEEKGE-------- --------AEDESCEMTWKKSQRLAGGLMRFSINLLREAQVE---SNGTNVILSPLSIAL ALSHLALGAANQTEKHLLAAMHLQS---------VPCLHHVLGTLRRRFT---------- -------ESTLSLASRLYLQKGFEVKDKFLEDSEKFYGAKPMTLS--GMGEDDLVAINTW VKEATNGQIPTFLQ--QLPANTVLLLLNAIHFHGVWRNKFDANFTGPD--VFHLDSKF-M VPVEMMKAQRYPLSWFTLESQDIQVAKFPFQS------NMSFVVIVPNQYTWNLSHVLEN FPYEQLCRLFPREV-------PTTVKIPKIKLDYQLELNKVLSQMGLQELFTS--PNLQK ISD-----EPLFVSSVQHQSTLELKEDGVEASAATSVAVSR-SVS-------AFSLDQPF VFIIFEDETGIPLFIGSVQNPNPNAAPQIKEPRDSHKATDVNEY---------------- -------------PMPK >XP_005693371.2 PREDICTED: alpha-2-antiplasmin isoform X1 [Capra hircus] ------------------------------------------------------------ ----------------------MALL-WGLL---------------ALSLSCLPSPCSAQ FSPVSAMEPL-----------GLQLMSGQAQ------------EKLPPLSLLKLGN---- ------------------------------------------------------------ ------------------------------------QEPGGQIA-PKKAPG--------- ----------DCKASPTPEQTRRLARAMMTFTTDLFSLVAQS---STRPNLILSPLSVAL ALSHLALGAQNQTLQRLKQVLHADS---------GPCLPHLLSRLCQDLG---------- -------PGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPMSLT--GRKGEDLANINQW VKEATEGKIEDFLS--DLPDDTVLLLLNAIHFQGFWRNKFDPNLTQRD--TFHLDEQF-T VPVDMMQALTYPLHWFLLEQPEIQVAHFPFKN------NMSFVVLMPTRFEWNVSQVLAN LTWDILHQPLLRER-------PTKVQLPKLHLKYQLDLVATLSQLGLQELFQA--PDLRG ISD-----ERLVVSSVQHQSALELSEAGVEAAAATSTAMSRMSLS-------SFVVNRPF LFFILEDSTSLPLFVGSVRNPNPGAQPERKEQQDSPG-RDSFQDHKGRPRGDKPFDPDLK LGPPS-EEDYPQPSSPK >XP_006032910.1 alpha-2-antiplasmin [Alligator sinensis] ------------------M----------------------------------------- ----------------------AVLL-WGLL---------------LLCLSALHHRPW-- CPLAYALEMDFTPSLHQDSSQGHEATGTSGQDLQPTVTSVTLPAAVSTLPNAVVSDST-- SDTWEDIHGPTLP-PTPTPTT---TTTTTTVCRDKFMSPEGEP----------------- ---------------------VTGTVG------SHEQVLEGQEVDSSEEE---------- ---------EERNCNISQERMRKLADGLMKFTADLLQEVERE---NSQPNMVLSPLSITL ALSHLALGAENQTEKHLLEAMHLKS---------VPCLHHTLSSIRRVLT---------- -------ESLLSVASQLYLQKGLEVKEKFLENSERFYGAKPVTLS--GNKEDDLIAINKW VQEVTKGHISSFLS--QLPDSMVMLLLNAVYFRGFWRNKFDASLTGPD--MFHLNDEF-M VPVEMMKAPKYSLSWFTLDSLEMQVARFPFKG------NMSFVAIVPNQFGWNVSEVLEN VSHDKLHGRFPKEK-------PTLVKMPKMHVDYKLELNEVLSRLGLKELFSA--PDLRK ITN-----EPLLVSSIQHQSTLELAEEGVEASAATSIMLSR-SLS-------TFSLDRPF LFIIFEETTGIPLFVGKIQNPNPSAAQQRKEPEDVSDVKSGLKD---------------- -------------SPPK >XP_006260669.2 PREDICTED: alpha-2-antiplasmin [Alligator mississippiensis] ------------------M----------------------------------------- ----------------------AVLL-WGLL---------------LLCLSALHHRPW-- CPLAYALEMDFTPSLHQDSSQGHEATGTSGQDLQPTVTSVTLPAAVSTLSNAVVSDST-- SDTWEDIHGPTLP---PTPTT---TTTTTTVCRDKFMSPEGEP----------------- ---------------------VTGTVG------SHEQVLEGQEVDSSEEEEN-------- --------HEESNCNISQERMRKLADGLMKFTADLLQEVEWE---NSQPNMVLSPLSITL ALSHLALGAENQTEKHLLEAMHLKS---------VPCLHHTLSSIRSVLT---------- -------ESMLSVASQLYLQKGLEVKEKFLENSERFYGAKPVTLS--GNKEDDLIAINKW VKEVTKGHISSFLS--QLPDSMVMLLLNAVYFRGFWRNKFDASLTGPD--MFHLNDEF-M VPVEMMKAPKYSLSWFTLDSLEMQVARFPFKG------NMSFVAIVPNQFGWNVSEVLQN VSHDKLRGRFPKEK-------PTLVKMPKMHVDYKLELNEVLSRLGLKELFSA--PDLRK ITD-----EPLLVSSIQHQSTLELAEEGVEASAATSIMLSR-SLS-------TFSLDRPF LFIIFEETMGIPLFVGKIQNPNPSAAQQRKEPEDVSDVKSGLKD---------------- -------------SPPK >XP_015806684.1 PREDICTED: alpha-2-antiplasmin [Nothobranchius furzeri] ------------------------------------------------------------ ----------------------MDLC-LTLL---------------LICLCSQG------ ATKAEVTED----------------------------------QSTPLVPLIPSQPIE-- EGESSTSE----PLASTD--------------------VATKE----------------- ---------------------------------LAAILTSNK---TSLDVNE-------- -------TGDCQSASQSPKSQQAIAAAVQNLGVQLLQNLETT---PEHPNIIISPLSISL ALSQLALGAKNETEELLMHHLHENA---------VPCYHRSLRDVLAQLK---------- -------KRDLQIATRIFLRQGFEAKHKFVSESQLFYGSEPAVLE-------SLQQINEW VENATNGRMTDFLF--TLPPNLLLMLINAVHFKGEWKARFDPNFTSRG--VFYLDDLH-M VDVDVMEDAKHQLSCFADNELEAQVARFPFTK------LMSLLVVMPESGQVNVSALCAK LNISDLYERLPKET-------AVQVKVPKFKLEYSQELQEVLTKLGLGEMFLN--PNLAD IAD-----GPLLVSSVMHKSSMEINEDGAEAAAATNIVISRAAIP-------VFHLTKPF FFVLMDDVTQIPIFMGVINNPNPGAPILQKGQFGSKDKMGFSYDKDHM----SSFG---- --------------GPK >XP_020765465.1 alpha-2-antiplasmin isoform X1 [Odocoileus virginianus texanus] ------------------------------------------------------------ ----------------------MALL-WGLL---------------VLSLSCLPSPCSAQ FSPVSAMEPL-----------GLQLMDGQAQ------------KKLPPLSLLKLGN---- ------------------------------------------------------------ ------------------------------------QEPGGQIA-PKKAPG--------- ----------DCKLSPTPEQTRRLARAMMTFTTDLFSLVAQS---STRPNLILSPLSVAL ALSHVALGAQNQTLQRLKQVLHADS---------GPCLPHLLSRLCQDLG---------- -------PGAFRLAARMYLQKGFPIKEDFLEQSEQLFGSKPMSLT--GRKGEDLANINQW VKEATEGKIEDFLS--DLPDDTVLLLLNAIHFQGFWRSKFDPNLTQRG--TFHLDEQF-T VPVDMMQALTYPLHWFLLEQPEIQVAHFPFKN------NMSFVVLMPTSFEWNVSQVLAN LTWDILHQPSLRER-------PTKVQLPKLRLKYQLDLVATLGQLGLQELFQA--PDLRG ISD-----ERLVVSSVQHQSALELSEAGVEAAAATSTAMSRMSLS-------SFIVNRPF LFFILEDSMSLPLFVGSVRNPNPGAQPERKEQQDSPDGRDSFQDHKGLPRGDKPFDPDLK LGPPS-EEDYPQPSSPK >XP_030249187.1 alpha-2-antiplasmin [Sparus aurata] ------------------------------------------------------------ ----------------------MDFH-LTLL---------------FICLCCQG------ VTNAEVADN----------------------------------ESIPLVPLIPLMPSH-- PIQKAENE----STAQPGT-------------TYTTEAPENVT----------------- ---------------------------------ATTNRTNGG---SSEEEQD-------- --------EDCLSIGRSPQSREAIAAAIQKLGVQLLQNLETS---AEQPNVIISPFSISL ALSQLALGAVNETQELLMHHLHENT---------LPCYHQSLHNVLMQLR---------- -------NNDLQIATRIFLRQEFQPKQDFVDESQRLYDSEPAILE-------SLQQINDW VDNATNGVMTDFLS--ALPPNLLLMLINAVHFKGEWKARFDPRFTSRG--VFYLDDKH-M VDVEVMEDAKHPLSLFIDNELEAQVARFPFQK------LMSLLVVMPLSGQVNVSSLSAK LNVSDLYNRLPKER-------AVQVKVPKFKLEYAQELQDVFTKLGLGEMFSS--PNLAE ISD-----GPLLVSSVLHKSSMEINEEGAEAAAATSVVISRASSP-------VFHLIQPF FFALMDDMTQVPIFMGVINNPNPGAPLLQRGDQGSKDKVGFPFDKNHV----GTFG---- -------------GPPK >XP_040194310.1 alpha-2-antiplasmin [Rana temporaria] ------------------------------------------------------------ ------------------------ML-ITLLCADSAGYRRIRIMGKVLFWFFLAGVC--- CSLAEVIDEEELP----ATEIETTLVSTT--------------PLTTKATHSNIVDST-- SDTWSDLF----PWAT------EFTTTSTPAIQNETEAPKYED----------------- -----------------------------------SIEDDQDEK-ISSSEN--------- ----------ACNGDFSKTEMNQFADAMMKFSTDLLKQVHLG---SKSSNVVVSPLSIAL GLLQLTLGAEKETEKKLLETLHVES---------MPCLHEKMHKVTKRLV---------- -------QTALNIASRMYVDKSFKMKEEFLVKSAKLYGSKPVNLG--PDMSQNLESINKW VSDATKGKITDFLS--SISEKVVLILLNAIHFKGVWKNKFDPRMTSED--TFYVNDEE-S MLVDMMQANKYPLRFFTSEKLDSQVAKLPFKG------NMSFVIVMPHQMEWNVSNILDK LNKSELYSRLHREK-------PTALRVPKLNLNFKLELTNALSSLGLGQLFRK--PDLGK ISD-----DELVVSSVEHQCTLDLNEEGVEAAAATAVVTSR-SLS-------TFSVNRPF LFLLIDDNTGLVLFFGYVREPKPSSPRKKKDP----ETKFLSKG---------------- -------------AIPK >XP_006572060.1 leukocyte elastase inhibitor [Apis mellifera] ------------------MA---------------------------------------- --------------KANMRESFRNIR-FTLT------------FFSVLFAPRISFVI--- HRMSELL------------------------------------HIIFIIMLGS------- ------------------------------------------------------------ ------------------------------------------------------------ --------SSATFSNNKENIGKYLSASYNNFTRDLYKELTST---NV-RNIVNSPLIIHM ILSHLSHGAESTTLNELTKSLYHYN---------KILIEEEYKSLIIKLN---------- ----ELSMVKLYIANAMYIQDGFEILTEFLTIGKDVYQSEISKVD-FKNNVEASQKINAW VNEKTNNKIPYFVSSDNFNENTKLILINAIYFNGTWLNIFNIRDTKDR--IFHVSKNQ-T KLIPTMYSKS-KYTHGDMPMLQAKFIEIPYKNP-----DVAMIIILPNQID-GLLNLQTN FSFEMLANTTRFYN-------DIKLYLPKFKIEFTIDLKNALNKLGLITMFKPN-ANFNR ISN-----TPLMVDKVLHKAIIDINEEGTEAAATTAVSLRLRRCIYPEE-TEKFIVDRPF MFILEYKPNNIPLFIGNVQDIEVISQRDE------------------------------- ----------------L >NP_524956.2 serpin 38F, isoform A [Drosophila melanogaster] ------------------------------------------------------------ ------------------------MK-YLCL----------------------------- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------------------LLLATSVSCRFTDDLYQLLAKE---NADKNLITSPLSVEI ALSLAYMGARGKTAQEMRDVLKLPD--------DKKEVAAKFKDLLSKLEGRES------ -------VAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAIS-ANNPKITASIVNKW VDTQTSGKIRDLVMPSDV-ANLVLVILNAIYFKGQWQKKFNTEQTKSD---FHISDQK-S VPVQMMSLVR-PFGVSYDRELGANVIELPYRNS-----NLSMVIFLPDKVD-GLPELEKK MV-----GFTPKLINI-----NVHLRLPKFKIEFSARLEQVLIAMGIQDAFKTS-ADFND LVA----NSGAHVGGVVHKAFLEVNEEGSEAAAATAVVFRYKSIRSPPM---DFNVNHPF AYVIRDAEN--IYFQGHFVNPE-------------------------------------- ----------------L >XP_031557330.1 leukocyte elastase inhibitor-like [Actinia tenebrosa] ------------------------------------------------------------ ------------------------MG-NNII---------------TCNTFRLHSVL--- ---------------------------------------------ILAVSLVF------- ------------------------------------------------------------ ------------------------------------------------------------ ----------CSVLLSTMAQADLIKASTNKFSLHLHQVLRGQATFDAEQNLFYSPSSILV ALAMTHLGARGNTAKQMSSSFHLDEI-------PEKQLNAEFQKFLQKLNQSNA------ ------KGNEIAMANRLFVQMGFEVSKQFQEDSEKFFNAEAALVDYQKNSEGARQEVNQW VEQKTKNKIKDLIPEGMFGPDTRLTLVNAIYFKGSWMSKFDSNNTQTG--PFQLTPSK-T VQVPMMYKSD-KFKYFENEGLKCKMLELPYSDE-----KISMIILLPDEVD-GLSKLEDS LNYSKLDEAIGHLKMAPK--EEVEVTLPKFKLSEKFSLKEVLSKMGASDLFNAAKADLTG INK----DGQLYVSEVVHKAFVDVNEEGTEAAAATAVRVALMCMPMNP----IFFANHPF LFLIRHNESGAILFIGRLANPK-------------------------------------- ----------------- >XP_038050239.1 leukocyte elastase inhibitor-like [Patiria miniata] ------------------M----------------------------------------- ---------------------------YKLT---------------LLVTSSRPDSI--- MAVIQII------------------------------------SILTVIALLY------- ------------------------------------------------------------ ------------------------------------------------------------ --------MSVFATSTGPDPQLELADANNRFAFHLYQTLADD---PHRDNIFFSPMSISI ALAMTSLGARGNTARQIKDVLKFSTL-------EESRLHSSFAELNSAIFGANA------ ------DKYVLRKANRLFGHKGFDLRQEFLADAERYYSSHMASLDFVEDTEVAREFINSW VGRETEDKIRDLLPHGSITGMTQLVLVNAIYFKADWVRQFDKSKTFDQ--DFHVSKDQ-V LEVPMMHRKS-KFNFAEDITLRCKLIELPYVGQ-----DFSMIVVLPDEID-GIDRLQKH LTNEKLQHLLNNLSNV-----TVGVAIPKFKLEETLHMNDVLYSMGMRDLFVRDKADLSG ITG----TRDLFVSSVIHRAFLEVNEEGSEAAAATAVTINKRSISLAP----EFIADHPF LFFIADSKTKAIVFMGHCRKPEGVSLNHEE------------------------------ ----------------L >XP_039269246.1 serpin B9-like [Styela clava] ------------------M----------------------------------------- ----------------------IKMK-NIII----------------------------- -------------------------------------------SLGIAICLAVMSKAD-- ------------------------------------------------------------ ------------------------------------------------------------ -------KMKTSTTPSDECSMASGAEANRIFAYEMYKVAAKL---KPNQNIFLAPTTVGS GLSMMLPGARESTKDQMLEGLMFKNTSTGFEPNDIECLMKMYSNELIETKLEDRGKGTKD VKAAKEDTLQLRTANRLFGEKSFNFSSKFIEQTAK-YGVEMTKMNFQTDSAESRNFINQW VEKATEGKIKDLFSGKAIRPDTVLAVVSAIYFKGLWKYPFDPLNTFKQ--DFKVNDNK-T VKADFMTKMI-NYRMTYSEDLEAQILDVPYDGDAYGKYNASMILIVPTRRG-SIERVEEM LSEKTMKPILDELQAEQQYTQRVRLLLPKFKMSKTYQLKPILRRLGIKNLFNPIRANLSG MIDPSEISPNLYVSTAVHKTFIKVDEKGTEAAGASGFGIVPLSLP------PRLFCNRPF LFMIYEKNTDGVLFIGKVNDPTV------------------------------------- ----------------Q >NP_001122924.1 SERPIN domain-containing protein [Caenorhabditis elegans] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------MSDPKENMALLLQSETDFGLGL---LRQQ---NISESLAFSPLSIAL ALSLVHVAAKGETRDQIREALVKGS--------TDEQLEQHFANISAALLAAER------ -------GTEVKLANHVFTRAGFKIKQSYLDDVKKLYNAGASSLD-FDNKEATAEAINNF VRENTGDHIKKIIGSDSINSDLVAVLTNALYFKADWQNKFKKDSTFKS--EFFSSADS-K REIDFLHASSVSRDYAEND--QFQVLSLPYKDN-----TFALTIFLPKTRF-GLTESLKT LDSATIQHLLSNVSST-----SVNVQIPKWKIETKLGLEEALQSLGIKKAFDND-ADLGN MAD------GLYVSKVTHKALIEVDEEGTKAAAATTVSISLKSAMFVMEEPKDFTADHPF FFVLSKDNH--PLFVGLHH----------------------------------------- ----------------- >XP_030848953.1 leukocyte elastase inhibitor-like [Strongylocentrotus purpuratus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ --------MAFSKQQDTSGQLVQLSSANIGFALDLYQTLQDE---RRGTNLFFSPLSIST ALAMTQLGARGDTATQIADVFRFNQV-------DQDQLHGTFKELNNLLYQTDS------ -------GYKLHSANRLYGKSGYNFVQSFLEGTVFYYGAAIEAVN-DFASPIATQSINDW VSKQTEGKIKNLIAPGTLNDLTRLVLVNAIYFKANWKSKFYAENTTHDTCTFKVFDERYK VPVSLMSQKG-RFALTVDNTNDCLVLELPYESH-----NLSLLIALPTKDD-GLGQLETK LSVDVLQSWDVGLKSR-----RVNVLLPKFKLEATFQLKEVLKRMGMPDAFDEDRANFKG ISS---EEREFYISAVIHKAFINVNEEGSEAAAATAFVMAGGGPRIEREKPILFRADHPF LFMIRHRSTKSVLFMGRMMDPS-------------------------------------- ----------------- >XP_043759289.1 alpha-2-antiplasmin isoform X2 [Cervus elaphus] ------------------------------------------------------------ ----------------------MALL-WGLL---------------VLSLSCLPSPCSA- FSPVSAMEPL-----------GLQLMGGQAQ------------EKLPPLSLLKLGN---- ------------------------------------------------------------ ------------------------------------QEPGGQIA-PKKAPG--------- ----------ECKASPTPEQTRRLAQAMMTFTTDLFSLVAQS---STRPNLILSPLSVAL ALSHVALGAQNQTLQRLKQVLHADS---------GPCLPHLLSHLCQELG---------- -------PGAFRLAARMYLQKGFPIKEDFLEQSEQLFGSKPMSLT--GRKGEDLANINQW VKEATEGKIEDFLS--DLPDDTVLLLLNAIHFQGFWRSKFDPNLTQRG--TFHLDEQF-T VPVDMMQALTYPLHWFLLEQPEIQVAHFPFKN------NMSFVVLMPTSFEWNVSQVLAN LTWDILHQPSLRER-------PTKVQLPKLRLKYQLDLVATLSQLGLQELFQA--PDLRG ISD-----ERLVVSSVQHQSALELSEAGVEAAAATSTAMSRMSLS-------SFIVNRPF LFFILEDSMSLPLFVGSVRNPNPGAQPERKEQQDSPDGRDSFQDHKGLPRGDKPFDPDLK LGPPS-EEDYPQPSSPK >KAB0367107.1 hypothetical protein FD755_020431 [Muntiacus reevesi] ------------------------------------------------------------ ----------------------MALL-WGLL---------------VLSLSCLPSPCSAQ FSPVSAMEPL-----------GLQLMGGQAQ------------EKLPPLSLLKLGN---- ------------------------------------------------------------ ------------------------------------QEPGSQIA-PKKAPG--------- ----------DCKASPTPEQTRRLAQAMVTFTTDLFSLVAQS---STRPNLILSPLSVAL ALSHVALGAQNQTLQRLKQVLHADS---------GPCLPHLLSRLCQDLG---------- -------PGAFRLAARMYLQKGFPIKEDFLEQSEQLFGSKPMSLT--GRKGEDLANINQW VKEATEGKIEDFLS--DLPDDTVLLLLNAIHFQGFWRSKFDPNLTQRG--TFHLDEQF-T VPVDMMQALTYPLHWFLLEQPEIQVAHFPFKN------NMSFVVLMPTSFEWNVSQVLAN LTWDILHQPSLRER-------PTKVQLPKLRLKYQLDLVATLSQLGLQELFQA--PDLRG ISD-----ERLVVSSVQHQSALELSEAGVEAAAATSTAMSRMSLS-------SFIVNRPF LFFILEDSTSLPLFVGSVRNPNPGAQPERKEQQDSPDGRDSFQDHKGLPRGDKPFDPDLK LGPPS-EEDYPQPSSPK >KAB0366160.1 hypothetical protein FD754_010316 [Muntiacus muntjak] ------------------------------------------------------------ ----------------------MALL-WGLL---------------VLSLSCLPSPCSAQ FSPVSAMEPL-----------GLQLMGGQAQ------------EKLPPLSLLKLGN---- ------------------------------------------------------------ ------------------------------------QEPGSQIA-PKKAPG--------- ----------DCKSSPTPEQTRRLAQAMVTFTTDLFSLVAQS---STRPNLILSPLSVAL ALSHVALGAQNQTLQRLKQVLHADS---------GPCLPHLLSRLCQDLG---------- -------PGAFRLAARMYLQKGFPIKEDFLEQSEQLFGSKPMSLT--GRKGEDLANINQW VKEATEGKIEDFLS--DLPDDTVLLLLNAIHFQGFWRSKFDPNLTQRG--TFHLDEQF-T VPVDMMQALTYPLHWFLLEQPEIQVAHFPFKN------NMSFVVLMPTSFEWNVSQVLAN LTWDILHQPSLRER-------PTKVQLPKLRLKYQLDLVATLSQLGLQELFQA--PDLRG ISD-----ERLVVSSVQHQSALELSEAGVEAAAATSTAMSRMSLS-------SFIVNRPF LFFILEDSTSLPLFVGSVRNPNPGAQPERKEQQDSPDGRDSFQDHKGLPRGDKPFDPDLK LGPPS-EEDYPQPSSPK >XP_043334282.1 alpha-2-antiplasmin isoform X2 [Cervus canadensis] ------------------------------------------------------------ ----------------------MALL-WGLL---------------VLSLSCLPSPCSA- FSPVSAMEPL-----------GLQLMGGQAQ------------EKLPPLSLLKLGN---- ------------------------------------------------------------ ------------------------------------QEPGGQIA-PKKAPG--------- ----------ECKASPTPEQTRRLAQAMMTFTTDLFSLVAQS---STRPNLILSPLSVAL ALSHVALGAQNQTLQRLKQVLHADS---------GPCLPHLLSHLCQELG---------- -------PGAFRLAARMYLQKGFPIKEDFLEQSEQLFRSKPMSLT--GRKGEDLANINQW VKEATEGKIEDFLS--DLPDDTVLLLLNAIHFQGFWRSKFDPNLTQRG--TFHLDEQF-T VPVDMMQALTYPLHWFLLEQPEIQVAHFPFKN------NMSFVVLMPTSFEWNVSQVLAN LTWDILHQPSLRER-------PTKVQLPKLRLKYQLDLVATLSQLGLQELFQA--PDLRG ISD-----ERLVVSSVQHQSALELSEAGVEAAAATSTAMSRMSLS-------SFIVNRPF LFFILEDSMSLPLFVGSVRNPNPGAQPERKEQQDSPDGRDSFQDHKGLPRGDKPFDPDLK LGPPS-EEDYPQPSSPK >KAF4012197.1 hypothetical protein G4228_003071 [Cervus hanglu yarkandensis] ------------------------------------------------------------ ----------------------MALL-WGLL---------------VLSLSCLPSPCSAQ FSPVSAMEPL-----------GL------------------------------------- ------------------------------------------------------------ ------------------------------------QEPGGQIA-PKKAPG--------- ----------ECKASPTPEQTRRLAQAMMTFTTDLFSLVAQS---STRPNLILSPLSVAL ALSHVALGAQNQTLQRLKQVLHADS---------GPCLPHLLSHLCQELG---------- -------PGAFRLAARMYLQKGFPIKEDFLEQSEQLFGSKPMSLT--GRKGEDLANINQW VKEATEGKIEDFLS--DLPDDTVLLLLNAIHFQGFWRSKFDPNLTQRG--TFHLDEQF-T VPVDMMQALTYPLHWFLLEQPEIQVAHFPFKN------NMSFVVLMPTSFEWNVSQVLAN LTWDILHQPSLRER-------PTKVQLPKLRLKYQLDLVATLSQLGLQELFQA--PDLRG ISD-----ERLVVSSVQHQSALELSEAGVEAAAATSTAMSRMSLS-------SFIVNRPF LFFILEDSMSLPLFVGSVRNPNPGAQPERKEQQDSPDGRDSFQDHKGLPRGDKPFDPDLK LGPPS-EEDYPQPSSPK >XP_018101643.1 alpha-2-antiplasmin isoform X4 [Xenopus laevis] ------------------------------------------------------------ -------------------------M-ERLL---------------LLCLIVLSGIN--- GSSAYTTEVPP------DANIEDKNVTTQHY------------ETTSIPE-----DST-- SDTWEDLH----PLVTTACRTIDFETTTASDSDNLGSEDKLEEGSDDKLEEGSDDKLEEG SDDKLEEGPEDKLEEEPEDKLEEGPEDKLEEDPLKKLEEGADEK-HPSEDNEPCKLVMDD NDDDNEVEQESCDENASLEEMRKFSQAITSFSIDLLKEIDPE---SQKPSAVMSPFSIAL GLLQLSLGAGKEMQDKLMETLHVES---------LHCLHNKLKTVRKELT---------- -------TSILRTATRIYLKKGFQIKKSFLKRSEKWYGSKPMNLA--SKKKQNLDSINKW VKDVTEGQIPHFLS--DLPQNVALILLNAMHFKGIWKNTFDPSLTSEE--IFYINDDV-G VPVEMMSAQKYPFSWFYLDGIEGHVAKLQFKG------NMSFVILMPFSSTWNLSKLLAN FNQSDLYSRFPKEK-------ASNLKMPKLNLDYKLELNEALTNLGLGQLFTN--PDLSG ITN-----EPLFVSSIQHQSSLELNEEGVEASAATAVMTSR-SHS-------VFRINRPF IFFLFEDTMGLPLFMGQVRDPSSGYQKKSSSK----DKKNFNNG---------------- -------------FLPK
BMGE Cleaned alignment of selected proteins >sp|P08697|A2AP_HUMAN Alpha-2-antiplasmin OS=Homo sapiens OX=9606 GN=SERPINF2 PE=1 SV=3 VLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVSPLTLLKLGNQEPGGQTALKSPPGHRLARAMAFTADLFSLVAPNLILSPLSVALALSHLALGAQNHTLQRLQQVLHAGSGPCLPHLLSRLCPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLTGKQEDDLANINQWVKEATEGKIQEFLSGLPEDTVLLLLNAIHFQGFWRNKFDPSLTQRDSFHLDEQFTVPVEMMQARTYPLRWFLLEQPEIQVAHFPFKNNMSFVVLVPTEWNVSQVLANLSWDTLHPLVWERPTKVRLPKLYLKHQMDLVATLSQLGLQELFQPDLRGISESLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLSSFSVNRPFLFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDLKGFPRGDKLFGPDLKLVPPMEEDYPQFGSPK >sp|P08697-2|A2AP_HUMAN Isoform 2 of Alpha-2-antiplasmin OS=Homo sapiens OX=9606 GN=SERPINF2 VLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVSPLTLLKLGNQ-----------------------------------------------VQPGAQNHTLQRLQQVLHAGSGPCLPHLLSRLCPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLTGKQEDDLANINQWVKEATEGKIQEFLSGLPEDTVLLLLNAIHFQGFWRNKFDPSLTQRDSFHLDEQFTVPVEMMQARTYPLRWFLLEQPEIQVAHFPFKNNMSFVVLVPTEWNVSQVLANLSWDTLHPLVWERPTKVRLPKLYLKHQMDLVATLSQLGLQELFQPDLRGISESLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLSSFSVNRPFLFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDLKGFPRGDKLFGPDLKLVPPMEEDYPQFGSPK >tr|F1RAP6|F1RAP6_DANRE Serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium-derived factor), member 2b OS=Danio rerio OX=7955 GN=serpinf2b PE=3 SV=1 LLCYSKQG-----WTD-DVTDPE----------GVDPVIPLIPLTPGPSSGQKESSEEELRTIGNGIKLGLLFLENLKPNVIFSPLSLSVALSQLALGATNDTEELLLHHLHADALPCYHTALSSLLKRSMPIASRIYLKTGFKAKSDFMEDSQKLYDSEPATLT-----DVNDVNEWVKKVTNGHISEFLSSLPPSAVMMLINAMHYKGEWLTRFDPHFTSTENFYIDENQIVNVDMMLGPKYPLSVFTHHELDAQVARFPFKGDRSLLVVMPTHVNVSAIAAKLNISDLYRLPRERNMQVKLPKFKLDFNQDLQEAMTSMGLGKLFSPKLDRITEPLFVSSVQHMSSVEINEEGAEAVAATSVVISR-SNPSFTVNQPFFFALMDDLSQTPLFLGVISNPNPGASTMITNPGNADKTDD----------------------------VHPK >NP_032904.1 alpha-2-antiplasmin precursor [Mus musculus] VLSLSCLQGPCFTFSPVSAVDLPGQQPVSEQAQQKLPLPALFKLDNQDFGDHATLKRSPGRRLAQAMAFTTDLFSLVASNLVLSPLSVALALSHLALGAQNQTLHSLHRVLHMNTGSCLPHLLSHFYPGTIRLAARIYLQKGFPIKDDFLEQSERLFGAKPVKLTGKQEEDLANINQWVKEATEGKIEDFLSELPDSTVLLLLNAIHFHGFWRTKFDPSLTQKDFFHLDERFTVSVDMMHAVSYPLRWFLLEQPEIQVAHFPFKNNMSFVVVMPTEWNVSEVLANLTWDTLYPSLQERPTKVWLPKLHLQQQLDLVATLSQLGLQELFQPDLRGISENLVVSSVQHQSTMELSEAGVEAAAATSVAMNRMSLSSFTVNRPFLFFIMEDTIGVPLFVGSVRNPNPSALPQLQEQRDSPDNRLDKADFHGGKTFGPDLKLAPRMEEDYPQFSSPK >NP_777095.1 alpha-2-antiplasmin precursor [Bos taurus] ALILSCLSSLCSAFSPVSTMEPLDLQLMDGQAQQKLPPLSLLKLDNQEPGGQIAPKKAPERRLARAMTFTTDLFSLVAPNLILSPLSVALALSHLALGAQNQTLQRLKEVLHADSGPCLPHLLSRLCPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPMSLTGMKGEDLANINRWVKEATEGKIEDFLSDLPDDTVLLLLNAIHFQGFWRSKFDPNLTQRGAFHLDEQFTVPVDMMQALTYPLHWFLLEQPEIQVAHFPFKNNMSFVVLMPTEWNASQVLANLTWDILHPSLSERPTKVQLPKLHLKYQLDLVATLSQLGLQELFQPDLRGISDRLVVSSVQHQSALELSEAGVQAAAATSTAMSRMSLSSFIVNRPFLFFILEDSTSLPLFVGSVRNPNPGAQPERKEQQDSPDGKDHKGLPRGDKPFDPDLKLGPPSEEDYAQPSSPK >NP_001011892.1 alpha-2-antiplasmin precursor [Rattus norvegicus] VLSLSCLQGPSSMFSPVSAMDLPGQQPVSEQAQQKLPPLALLKLGNQDLGDHATLKRSPGRRLSQAMAFTTDLFSLVASNLVLSPLSVALALSHLALGARNQTLENLQRVLHMNMGSCIPHLLSHFCPGTIRLAARIYLQKGFPIKDDFLEQSEKLFGAKPVKLTGRQEEDLMNINKWVKEATEGKIEDFLSELPDNTVLLLLNAIHFHGFWRTKFDPSLTQKDSFHLDEQFTVPVAMMHAQSYPLRWFLLEQPEIQVAHFPFQNNMSFVVIMPTGWNVSEVLANLTWDTLYPSMREKPTKVRLPKLHLEQHLDLVATLSKLGLQDLFQPDLRGISDSLVVSSVQHQSTMELSEAGVEAAAATSTAMTRMSLSSFFLNRPFIFFIMEETIGIPLFVGSVRNPDPSAQPQPQEQQDSPDNRRDKADIPGGKTFAPDLKLVPRLEEDYPQFSSPK >XP_016786642.1 alpha-2-antiplasmin isoform X2 [Pan troglodytes] VLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVSPLTLLKLGNQEPGGQTALKSPPGRRLARAMAFTADLFSLVAPNLILSPLSVALALSHLALGAQNHTLQRLQQVLHAGSGPCLPHLLSRLCPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLTGKQEDDLANINQWVKEATEGKIQEFLSGLPEDTVLLLLNAIHFQGFWRNKFDPSLTQRDSFHLDEQFTVPVEMMQARTYPLRWFLLEQPEIQVAHFPFKNNMSFVVLVPTEWNVSQVLANLSWDTLHPLVWERPTKVRLPKLYLKHQMDLVATLSQLGLQELFQPDLRGISESLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLSSFSVNRPFLFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDLKGFPRGDKLFGPDLKLVPPMEEDYPQFGSPK >XP_005624992.1 alpha-2-antiplasmin isoform X1 [Canis lupus familiaris] VISLSCLQGSGAVFPPASAMEPLDQQLMGGQTQEKLPPLTLLKLGNQESSGHIGLKKAPRRRLAQAMAFTTDLFSLVAPNLILSPLSVALALSHLALGAQNQTLRRLEQVLHADSGPCLPHLLSRLCPGAFRLAARMYLQKGFPIKEDFLKQSEQLFGAKPMSLTGRKGDDLLNINQWVKEATEGKIEDFLSELPDDTVLLLLNAIHFQGFWRSKFDPSLTQRDSFHLNEQFTVPVDMMHARTYPLRWFLLEQPEIQVAHFPFKNNMSFVVIMPTEWNVSQVLANLSWDILHPLLREKPTKVRLPKLHLNYQLDLVATLSRLGLQELFQPDLRGISDRLVVTSVQHQSALELSEAGVEAAAATGTAMSRMSLSSFSVNRPFLFFILEDTTSLPLFVGSVKNPNPSAPWERKEQQDSPDDRDRKAFPRGDKPFGPDLKLAPPSEEDYPQLHSPK >XP_008268885.1 PREDICTED: alpha-2-antiplasmin isoform X1 [Oryctolagus cuniculus] VLSLSCLQGPCAVLPPVSAMEPVGRQLTSGQSQEKLPPLALLKLVNQELHGQTALKKSPGRRLAQAMAFTTDLFSLVVPNLVLSPLSVALALSHLALGAQNHTLQRLQQVLHADSGPCLPHLLSHLCPGAFRLAARMYLQKGFPIKEDFLKLSEQLFGAKPVSLTGRQEEDLVNINQWVKEATEGKIEDFLSELPDSTVLLLLNAIHFQGFWRSKFDPSLTQRDSFHLDEQFTVPVDMMQAHKYPLRWFLLEQPEIQVAQFPFKNNMSFVVLVPTEWNVSQVLSNLSWDILHPSLRERPTKVQLPKLLLKHQLDLVTTLSQLGLQELFLPDLRGISDGLVVSSVQHQSTLELNEAGVEAAAATSTAMSRMSLSSFSVNRPFLFFILEDTIDLPIFVGIVRNPNPSAQPERKEQQDSPDHRDQKSFPHGDKLFSPDLKLAPPSEEDYPQLSSPK >XP_002826863.1 alpha-2-antiplasmin isoform X1 [Pongo abelii] VLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPTQEQVPPLTLLKLGNQEPGGRTALKSPPGRRLAQAMAFTADLFSLVAPNLILSPLSVALALSHLALGAQNHTLQRLQQVLHAGSGPCLPHLLSRLCPGAFRLAARMYLQKGFPIKEDFLEQSQRLFGAKPVRLTGKQEDDLANINQWVKEATEGKIQEFLSELPEDAVLLLLNAIHFQGFWRNKFDPSLTQRDSFHLDEQFTVPVEMMQARTYPLRWFLLEQPEIQVAHFPFKNNMSFVVLVPTEWNVSKVLANLSWDTLHPLVWERPTKVRLPKLYLKHQMDLVATLSQLGLQELFQPDLRGISESLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLSSFSVNRPFLFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDLKGFPRGDKLFGPDLKLAPPLEEDYPQFGSPK >XP_020923238.1 alpha-2-antiplasmin [Sus scrofa] VLSLFCLH----VLPPVSAMDPLGLQLMIGQGQEKLSPLSLLELDNQEHGGHTALNEAPGRRLAQAMAFTRDLFSLVAPNLVLSPLSVALALSHLALGAQNQTLQRLQQVLHADSGPCLPYLLSRLCPGAFRLAARMYLQKGFPIKEDFLEQSEELFGAKPMSLTGRKGDDLANINQWVKEATEGKIEDFLSDLPEDTVLLLLNAIHFQGFWRSKFDPNLTQRDTFHLDEQFTVPVDMMQARMYPLRWFLLEQPEIQVAYFPFKNNMSFVVMVPIEWNVSQVLANLSWDILHPLLRERPTKVQLPKLHLKYQLDLVATLSQLGLQGLFQPDLRGISDSLVVSSVQHQSTLELSEAGVEAAAATSTAMSRMSL-SFSVNRPFLFFILEDTTSLPLFVGSVRNPNPGAQPERKEQQDSPDSRYQKAFPRGDKPFYPDLKLAPPSEEDYPQPSGPK >XP_024997830.2 alpha-2-antiplasmin [Gallus gallus] LLSLSALHSHPR-LPLAHAVEQQDLKNLKSGGDEAIPTLLDAKLADQEPSGKTLSSEEEGQKLANGLRFSTDLLREVQNNVILSPLSIALALSNLALGAANQTEKRLLEAMHLESVPCLHHMLSSLRGATLSLASRVYLQKGYEVKEEFLEESEKFYGAKPVTLSGSSEDDLTAINKWVKEATNGQIPTFLQQLPGDTVMLLLNAIHFHGFWRNKFDASFTAPDAFHLSDDFVVSVEMMKAQRYPLSWFTLESQDIQVAKFPFKGNMSFVVIVPNTWNTSHVLENFPYGQLCLFPKEVPTTVKIPKITLDYQLELNSVLSHMGLQELFIPNLQKISDPLFVSSIQHQSTMELKEDGVEASAATGVMISR-SLSAFSIDRPFIFILFEEEMGIPLFIGSVKNPNPNAAPQVKELQDLPDATD----------------------------TMPK >XP_003816899.2 alpha-2-antiplasmin isoform X2 [Pan paniscus] VLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVSPLTLLKLGNQEPGGQTALKSPPGRRLARAMAFTADLFSLVAPNLILSPLSVALALSHLALGAQNHTLQRLQQVLHAGSGPCLPHLLSRLCPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLTGKQEDDLANINQWVKEATEGKIQEFLSGLPEDTVLLLLNAIHFQGFWRNKFDPSLTQRDSFHLDEQFTVPVEMMQARTYPLRWFLLEQPEIQVAHFPFKNNMSFVVLVPTEWNVSQVLANLSWDTLHPLVWERPTKVRLPKLYLKHQMDLVATLSQLGLQELFQPDLRGISESLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLSSFSVNRPFLFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDLKGFPRGDKLFGPDLKLVPPMEEDYPQFGSPK >XP_006940042.1 alpha-2-antiplasmin isoform X2 [Felis catus] LLGLSCLQGPCLVFSAASAMEPSDQQLMSGPAQEKLPPLILLKLGNQEPSGHIALKKAPRRKLAQAMAFTTDLFSLVAPNLILSPLSVALALSHLALGAQNQTLQKLLQVLHADSGPCLPHLLSHLCPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLTGRKRDDLVNINQWVKEATEGKIEDFLSELPDDTVLLLLNAIHFQGFWRSKFDPSLTQRDSFHLNEEFTVPVDMMQARTYPLRWFLLEQPEIQVAHFPFKNNMSFVVIMPTEWNVSQVLANLSWDILHPLLREKPTKVQLPKLHLKYQLDLVATLSQLGLQELFQPDLRGISDRLVVSSVQHQSTLELSEAGVEAAAATGTAMSRMSLSSFIVNRPFVFFILEDTTSMPLFVGSVRNPNPSAQWERKEQQDSPDDRDQKAFPRGDKPFGPDLKLAPPSEEDYPQPNSPK >XP_004012597.3 alpha-2-antiplasmin isoform X2 [Ovis aries] ALSLSCLPSPCSAFSPVSAMEPLGLQLMSGQAQEKLPPLSLLKLGNQEPGGQIAPKKAPGRRLARAMTFTTDLFSLVAPNLILSPLSVALALSHLALGAQNQTLQRLKQVLHADSGPCLPHLLSRLCPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPMSLTGRKGEDLANINQWVKEATEGKIEDFLSDLPDDTVLLLLNAIHFQGFWRNKFDPNLTQRDTFHLDEQFTVPVDMMQALTYPLHWFLLEQPEIQVAHFPFKNNMSFVVLMPTEWNVSQVLANLTWDILHPLLRERPTKVQLPKLHLKYQLDLVATLSQLGLQELFQPDLRGISDRLVVSSVQHQSALELSEAGVEAAAATSTAMSRMSLSSFVVNRPFLFFILDDSTSLPLFVGSVRNPNPGAQPERKEQQDSPS-RDHKGRPRGDKPFDPDLKLGPPSEEDYPQPSSPK >XP_018868995.1 alpha-2-antiplasmin isoform X2 [Gorilla gorilla gorilla] VLSWSCLQGPCSVFSPVSAMEPLGRQLTSGPNQEQVPPLTLLKLGNQEPGGQTALKSPPGRRLARAMAFTADLFSLVAPNLILSPLSVALALSHLALGAQNHTLQRLQQVLHAGSGPCLPHLLSRLCPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPVSLTGKQEDDLANINQWVKEATEGKIQEFLSGLPEDTVLLLLNAIHFQGFWRNKFDPSLTQRESFHLDEQFTVPVEMMQARTYPLRWFLLEQPEIQVAHFPFKNNMSFVVLVPTEWNVSQVLANLSWDTLHPLVWERPTKVRLPKLYLKHQMDLVATLSQLGLQELFQPDLRGISESLVVSGVQHQSTLELSEVGVEAAAATSIAMSRMSLSSFSVNRPFLFFIFEDTTGLPLFVGSVRNPNPSAPRELKEQQDSPGNKDLKGFPRGDKLFGPDLKLVPPMEEDYPQFGSPK >XP_004075378.1 alpha-2-antiplasmin isoform X1 [Oryzias latipes] FICLCSRG-----VTNAEAADD-----------DSVPVVPLIPLINGSISGG--SASDEDQAITAAIKLGVQLLQNLEPNLIISPLSISLALSQLALGAENETEELLMHHLHENSVPCYHQSLHNVLNRDLQIATGIFLGQGFEAKQEFVSESKQLYHSEPAMLE-----NLQQINDWVENATQGKMSDFLSSLPSNLLLMLINAVHFKGEWKARFDPRFTTRGVFHLDDMHMVDVEVMEDAKHPLSSFTDHDLGAQVAKFPFMKLMSLLVVMPLQVNVSSLSAKLNISDLYRLPKERAVQVKVPKFKLEYSQELQEVLTRLGLGEMFQPNLADIADPLLVSSVKHKSIMEINEEGAEAAASTSVVISRASNPVFHLSQPFFFVLIDDMTLIPIFMGVINNPNPGGPILQRGEFGNRDKAGKNSM----ADFE----------------RSPK >XP_005502065.1 alpha-2-antiplasmin isoform X1 [Columba livia] LLCLSALHSHLR-FSSAHALEQKELKDVKSAGVEAVPTLPNADLADQQPAGESASSEEKGQRLAGGLRFSINLLREAQTNVILSPLSIALALSHLALGAANQTEKHLLAAMHLQSVPCLHHVLGTLRESTLSLASRLYLQKGFEVKDKFLEDSEKFYGAKPMTLSGMGEDDLVAINTWVKEATNGQIPTFLQQLPANTVLLLLNAIHFHGVWRNKFDANFTGPDVFHLDSKFMVPVEMMKAQRYPLSWFTLESQDIQVAKFPFQSNMSFVVIVPNTWNLSHVLENFPYEQLCLFPREVPTTVKIPKIKLDYQLELNKVLSQMGLQELFTPNLQKISDPLFVSSVQHQSTLELKEDGVEASAATSVAVSR-SVSAFSLDQPFVFIIFEDETGIPLFIGSVQNPNPNAAPQIKEPRDSHKATD----------------------------PMPK >XP_005693371.2 PREDICTED: alpha-2-antiplasmin isoform X1 [Capra hircus] ALSLSCLPSPCSAFSPVSAMEPLGLQLMSGQAQEKLPPLSLLKLGNQEPGGQIAPKKAPGRRLARAMTFTTDLFSLVAPNLILSPLSVALALSHLALGAQNQTLQRLKQVLHADSGPCLPHLLSRLCPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGAKPMSLTGRKGEDLANINQWVKEATEGKIEDFLSDLPDDTVLLLLNAIHFQGFWRNKFDPNLTQRDTFHLDEQFTVPVDMMQALTYPLHWFLLEQPEIQVAHFPFKNNMSFVVLMPTEWNVSQVLANLTWDILHPLLRERPTKVQLPKLHLKYQLDLVATLSQLGLQELFQPDLRGISDRLVVSSVQHQSALELSEAGVEAAAATSTAMSRMSLSSFVVNRPFLFFILEDSTSLPLFVGSVRNPNPGAQPERKEQQDSPG-RDHKGRPRGDKPFDPDLKLGPPSEEDYPQPSSPK >XP_006032910.1 alpha-2-antiplasmin [Alligator sinensis] LLCLSALHHRPW-CPLAYALEMDGHEATGTSGQAAVSTLPNAVVSDQVLEGQEVSSEEE-RKLADGLKFTADLLQEVEPNMVLSPLSITLALSHLALGAENQTEKHLLEAMHLKSVPCLHHTLSSIRESLLSVASQLYLQKGLEVKEKFLENSERFYGAKPVTLSGNKEDDLIAINKWVQEVTKGHISSFLSQLPDSMVMLLLNAVYFRGFWRNKFDASLTGPDMFHLNDEFMVPVEMMKAPKYSLSWFTLDSLEMQVARFPFKGNMSFVAIVPNGWNVSEVLENVSHDKLHRFPKEKPTLVKMPKMHVDYKLELNEVLSRLGLKELFSPDLRKITNPLLVSSIQHQSTLELAEEGVEASAATSIMLSR-SLSTFSLDRPFLFIIFEETTGIPLFVGKIQNPNPSAAQQRKEPEDVSDVKS----------------------------SPPK >XP_006260669.2 PREDICTED: alpha-2-antiplasmin [Alligator mississippiensis] LLCLSALHHRPW-CPLAYALEMDGHEATGTSGQAAVSTLSNAVVSDQVLEGQEVSSEEEERKLADGLKFTADLLQEVEPNMVLSPLSITLALSHLALGAENQTEKHLLEAMHLKSVPCLHHTLSSIRESMLSVASQLYLQKGLEVKEKFLENSERFYGAKPVTLSGNKEDDLIAINKWVKEVTKGHISSFLSQLPDSMVMLLLNAVYFRGFWRNKFDASLTGPDMFHLNDEFMVPVEMMKAPKYSLSWFTLDSLEMQVARFPFKGNMSFVAIVPNGWNVSEVLQNVSHDKLRRFPKEKPTLVKMPKMHVDYKLELNEVLSRLGLKELFSPDLRKITDPLLVSSIQHQSTLELAEEGVEASAATSIMLSR-SLSTFSLDRPFLFIIFEETMGIPLFVGKIQNPNPSAAQQRKEPEDVSDVKS----------------------------SPPK >XP_015806684.1 PREDICTED: alpha-2-antiplasmin [Nothobranchius furzeri] LICLCSQG-----ATKAEVTED-----------QSTPLVPLIPSQPILTSNK--TSLDVNQAIAAAVNLGVQLLQNLEPNIIISPLSISLALSQLALGAKNETEELLMHHLHENAVPCYHRSLRDVLKRDLQIATRIFLRQGFEAKHKFVSESQLFYGSEPAVLE-----SLQQINEWVENATNGRMTDFLFTLPPNLLLMLINAVHFKGEWKARFDPNFTSRGVFYLDDLHMVDVDVMEDAKHQLSCFADNELEAQVARFPFTKLMSLLVVMPEQVNVSALCAKLNISDLYRLPKETAVQVKVPKFKLEYSQELQEVLTKLGLGEMFLPNLADIADPLLVSSVMHKSSMEINEDGAEAAAATNIVISRAAIPVFHLTKPFFFVLMDDVTQIPIFMGVINNPNPGAPILQKGQFGSKDKMGKDHM----SSFG-----------------GPK >XP_020765465.1 alpha-2-antiplasmin isoform X1 [Odocoileus virginianus texanus] VLSLSCLPSPCSAFSPVSAMEPLGLQLMDGQAQKKLPPLSLLKLGNQEPGGQIAPKKAPGRRLARAMTFTTDLFSLVAPNLILSPLSVALALSHVALGAQNQTLQRLKQVLHADSGPCLPHLLSRLCPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGSKPMSLTGRKGEDLANINQWVKEATEGKIEDFLSDLPDDTVLLLLNAIHFQGFWRSKFDPNLTQRGTFHLDEQFTVPVDMMQALTYPLHWFLLEQPEIQVAHFPFKNNMSFVVLMPTEWNVSQVLANLTWDILHPSLRERPTKVQLPKLRLKYQLDLVATLGQLGLQELFQPDLRGISDRLVVSSVQHQSALELSEAGVEAAAATSTAMSRMSLSSFIVNRPFLFFILEDSMSLPLFVGSVRNPNPGAQPERKEQQDSPDGRDHKGLPRGDKPFDPDLKLGPPSEEDYPQPSSPK >XP_030249187.1 alpha-2-antiplasmin [Sparus aurata] FICLCCQG-----VTNAEVADN-----------ESIPLVPLIPLMPNRTNGG--SSEEEQEAIAAAIKLGVQLLQNLEPNVIISPFSISLALSQLALGAVNETQELLMHHLHENTLPCYHQSLHNVLNNDLQIATRIFLRQEFQPKQDFVDESQRLYDSEPAILE-----SLQQINDWVDNATNGVMTDFLSALPPNLLLMLINAVHFKGEWKARFDPRFTSRGVFYLDDKHMVDVEVMEDAKHPLSLFIDNELEAQVARFPFQKLMSLLVVMPLQVNVSSLSAKLNVSDLYRLPKERAVQVKVPKFKLEYAQELQDVFTKLGLGEMFSPNLAEISDPLLVSSVLHKSSMEINEEGAEAAAATSVVISRASSPVFHLIQPFFFALMDDMTQVPIFMGVINNPNPGAPLLQRGDQGSKDKVGKNHV----GTFG----------------GPPK >XP_040194310.1 alpha-2-antiplasmin [Rana temporaria] VLFWFFLAGVC--CSLAEVIDEEETTLVSTT--PLTTKATHSNIVDIEDDQDEKISSSENNQFADAMKFSTDLLKQVHSNVVVSPLSIALGLLQLTLGAEKETEKKLLETLHVESMPCLHEKMHKVTQTALNIASRMYVDKSFKMKEEFLVKSAKLYGSKPVNLGPDMSQNLESINKWVSDATKGKITDFLSSISEKVVLILLNAIHFKGVWKNKFDPRMTSEDTFYVNDEESMLVDMMQANKYPLRFFTSEKLDSQVAKLPFKGNMSFVIVMPHEWNVSNILDKLNKSELYRLHREKPTALRVPKLNLNFKLELTNALSSLGLGQLFRPDLGKISDELVVSSVEHQCTLDLNEEGVEAAAATAVVTSR-SLSTFSVNRPFLFLLIDDNTGLVLFFGYVREPKPSSPRKKKDP----ETKF----------------------------AIPK >XP_006572060.1 leukocyte elastase inhibitor [Apis mellifera] VLFAPRISFVI--HRMSELL-------------HIIFIIMLGS-----------------KYLSASYNFTRDLYKELTRNIVNSPLIIHMILSHLSHGAESTTLNELTKSLYHYNKILIEEEYKSLIMVKLYIANAMYIQDGFEILTEFLTIGKDVYQSEISKVDKNNVEASQKINAWVNEKTNNKIPYFVSNFNENTKLILINAIYFNGTWLNIFNIRDTKDRIFHVSKNQTKLIPTMYSKS-KYTHGDMPMLQAKFIEIPYKNDVAMIIILPND-GLLNLQTNFSFEMLATTRFYNDIKLYLPKFKIEFTIDLKNALNKLGLITMFKANFNRISNPLMVDKVLHKAIIDINEEGTEAAATTAVSLRLRRCIKFIVDRPFMFILEYKPNNIPLFIGNVQDIEVISQRDE------------------------------------------L >NP_524956.2 serpin 38F, isoform A [Drosophila melanogaster] ------------------------------------------------------------LLATSVSRFTDDLYQLLAKNLITSPLSVEIALSLAYMGARGKTAQEMRDVLKLPDKKEVAAKFKDLLVAILSLANRIYVNNKFKLVPEYNQMVKDSFKAEAEAISNNPKITASIVNKWVDTQTSGKIRDLVMDV-ANLVLVILNAIYFKGQWQKKFNTEQTKSD-FHISDQKSVPVQMMSLVR-PFGVSYDRELGANVIELPYRNNLSMVIFLPDD-GLPELEKKMV-----FTPKLINVHLRLPKFKIEFSARLEQVLIAMGIQDAFKADFNDLVAGAHVGGVVHKAFLEVNEEGSEAAAATAVVFRYKSIRDFNVNHPFAYVIRDAEN--IYFQGHFVNPE-------------------------------------------------L >XP_031557330.1 leukocyte elastase inhibitor-like [Actinia tenebrosa] TCNTFRLHSVL------------------------ILAVSLVF-----------------DLIKASTKFSLHLHQVLRQNLFYSPSSILVALAMTHLGARGNTAKQMSSSFHLDEEKQLNAEFQKFLGNEIAMANRLFVQMGFEVSKQFQEDSEKFFNAEAALVDKNSEGARQEVNQWVEQKTKNKIKDLIPMFGPDTRLTLVNAIYFKGSWMSKFDSNNTQTGPFQLTPSKTVQVPMMYKSD-KFKYFENEGLKCKMLELPYSDKISMIILLPDD-GLSKLEDSLNYSKLDAIGHLKEVEVTLPKFKLSEKFSLKEVLSKMGASDLFNADLTGINKQLYVSEVVHKAFVDVNEEGTEAAAATAVRVALMCMPIFFANHPFLFLIRHNESGAILFIGRLANPK-------------------------------------------------- >XP_038050239.1 leukocyte elastase inhibitor-like [Patiria miniata] LLVTSSRPDSI--MAVIQII-------------SILTVIALLY-----------------LELADANRFAFHLYQTLADNIFFSPMSISIALAMTSLGARGNTARQIKDVLKFSTESRLHSSFAELNKYVLRKANRLFGHKGFDLRQEFLADAERYYSSHMASLDEDTEVAREFINSWVGRETEDKIRDLLPSITGMTQLVLVNAIYFKADWVRQFDKSKTFDQDFHVSKDQVLEVPMMHRKS-KFNFAEDITLRCKLIELPYVGDFSMIVVLPDD-GIDRLQKHLTNEKLQLLNNLSTVGVAIPKFKLEETLHMNDVLYSMGMRDLFVADLSGITGDLFVSSVIHRAFLEVNEEGSEAAAATAVTINKRSISEFIADHPFLFFIADSKTKAIVFMGHCRKPEGVSLNHEE-----------------------------------------L >XP_039269246.1 serpin B9-like [Styela clava] ---------------------------------SLGIAICLAVMSK--------------ASGAEANIFAYEMYKVAAQNIFLAPTTVGSGLSMMLPGARESTKDQMLEGLMFKNIECLMKMYSNELTLQLRTANRLFGEKSFNFSSKFIEQTAK-YGVEMTKMNTDSAESRNFINQWVEKATEGKIKDLFSAIRPDTVLAVVSAIYFKGLWKYPFDPLNTFKQDFKVNDNKTVKADFMTKMI-NYRMTYSEDLEAQILDVPYDGNASMILIVPTG-SIERVEEMLSEKTMKILDELQRVRLLLPKFKMSKTYQLKPILRRLGIKNLFNANLSGMIDNLYVSTAVHKTFIKVDEKGTEAAGASGFGIVPLSLPRLFCNRPFLFMIYEKNTDGVLFIGKVNDPTV------------------------------------------------Q >NP_001122924.1 SERPIN domain-containing protein [Caenorhabditis elegans] ------------------------------------------------------------ALLLQSEDFGLGL---LRESLAFSPLSIALALSLVHVAAKGETRDQIREALVKGSDEQLEQHFANISGTEVKLANHVFTRAGFKIKQSYLDDVKKLYNAGASSLDDNKEATAEAINNFVRENTGDHIKKIIGSINSDLVAVLTNALYFKADWQNKFKKDSTFKSEFFSSADSKREIDFLHASSVSRDYAEND--QFQVLSLPYKDTFALTIFLPKF-GLTESLKTLDSATIQLLSNVSSVNVQIPKWKIETKLGLEEALQSLGIKKAFDADLGNMADGLYVSKVTHKALIEVDEEGTKAAAATTVSISLKSAMDFTADHPFFFVLSKDNH--PLFVGLHH----------------------------------------------------- >XP_030848953.1 leukocyte elastase inhibitor-like [Strongylocentrotus purpuratus] ------------------------------------------------------------VQLSSANGFALDLYQTLQTNLFFSPLSISTALAMTQLGARGDTATQIADVFRFNQQDQLHGTFKELNGYKLHSANRLYGKSGYNFVQSFLEGTVFYYGAAIEAVNFASPIATQSINDWVSKQTEGKIKNLIATLNDLTRLVLVNAIYFKANWKSKFYAENTTHDTFKVFDERKVPVSLMSQKG-RFALTVDNTNDCLVLELPYESNLSLLIALPTD-GLGQLETKLSVDVLQWDVGLKRVNVLLPKFKLEATFQLKEVLKRMGMPDAFDANFKGISSEFYISAVIHKAFINVNEEGSEAAAATAFVMAGGGPRLFRADHPFLFMIRHRSTKSVLFMGRMMDPS-------------------------------------------------- >XP_043759289.1 alpha-2-antiplasmin isoform X2 [Cervus elaphus] VLSLSCLPSPCSAFSPVSAMEPLGLQLMGGQAQEKLPPLSLLKLGNQEPGGQIAPKKAPGRRLAQAMTFTTDLFSLVAPNLILSPLSVALALSHVALGAQNQTLQRLKQVLHADSGPCLPHLLSHLCPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGSKPMSLTGRKGEDLANINQWVKEATEGKIEDFLSDLPDDTVLLLLNAIHFQGFWRSKFDPNLTQRGTFHLDEQFTVPVDMMQALTYPLHWFLLEQPEIQVAHFPFKNNMSFVVLMPTEWNVSQVLANLTWDILHPSLRERPTKVQLPKLRLKYQLDLVATLSQLGLQELFQPDLRGISDRLVVSSVQHQSALELSEAGVEAAAATSTAMSRMSLSSFIVNRPFLFFILEDSMSLPLFVGSVRNPNPGAQPERKEQQDSPDGRDHKGLPRGDKPFDPDLKLGPPSEEDYPQPSSPK >KAB0367107.1 hypothetical protein FD755_020431 [Muntiacus reevesi] VLSLSCLPSPCSAFSPVSAMEPLGLQLMGGQAQEKLPPLSLLKLGNQEPGSQIAPKKAPGRRLAQAMTFTTDLFSLVAPNLILSPLSVALALSHVALGAQNQTLQRLKQVLHADSGPCLPHLLSRLCPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGSKPMSLTGRKGEDLANINQWVKEATEGKIEDFLSDLPDDTVLLLLNAIHFQGFWRSKFDPNLTQRGTFHLDEQFTVPVDMMQALTYPLHWFLLEQPEIQVAHFPFKNNMSFVVLMPTEWNVSQVLANLTWDILHPSLRERPTKVQLPKLRLKYQLDLVATLSQLGLQELFQPDLRGISDRLVVSSVQHQSALELSEAGVEAAAATSTAMSRMSLSSFIVNRPFLFFILEDSTSLPLFVGSVRNPNPGAQPERKEQQDSPDGRDHKGLPRGDKPFDPDLKLGPPSEEDYPQPSSPK >KAB0366160.1 hypothetical protein FD754_010316 [Muntiacus muntjak] VLSLSCLPSPCSAFSPVSAMEPLGLQLMGGQAQEKLPPLSLLKLGNQEPGSQIAPKKAPGRRLAQAMTFTTDLFSLVAPNLILSPLSVALALSHVALGAQNQTLQRLKQVLHADSGPCLPHLLSRLCPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGSKPMSLTGRKGEDLANINQWVKEATEGKIEDFLSDLPDDTVLLLLNAIHFQGFWRSKFDPNLTQRGTFHLDEQFTVPVDMMQALTYPLHWFLLEQPEIQVAHFPFKNNMSFVVLMPTEWNVSQVLANLTWDILHPSLRERPTKVQLPKLRLKYQLDLVATLSQLGLQELFQPDLRGISDRLVVSSVQHQSALELSEAGVEAAAATSTAMSRMSLSSFIVNRPFLFFILEDSTSLPLFVGSVRNPNPGAQPERKEQQDSPDGRDHKGLPRGDKPFDPDLKLGPPSEEDYPQPSSPK >XP_043334282.1 alpha-2-antiplasmin isoform X2 [Cervus canadensis] VLSLSCLPSPCSAFSPVSAMEPLGLQLMGGQAQEKLPPLSLLKLGNQEPGGQIAPKKAPGRRLAQAMTFTTDLFSLVAPNLILSPLSVALALSHVALGAQNQTLQRLKQVLHADSGPCLPHLLSHLCPGAFRLAARMYLQKGFPIKEDFLEQSEQLFRSKPMSLTGRKGEDLANINQWVKEATEGKIEDFLSDLPDDTVLLLLNAIHFQGFWRSKFDPNLTQRGTFHLDEQFTVPVDMMQALTYPLHWFLLEQPEIQVAHFPFKNNMSFVVLMPTEWNVSQVLANLTWDILHPSLRERPTKVQLPKLRLKYQLDLVATLSQLGLQELFQPDLRGISDRLVVSSVQHQSALELSEAGVEAAAATSTAMSRMSLSSFIVNRPFLFFILEDSMSLPLFVGSVRNPNPGAQPERKEQQDSPDGRDHKGLPRGDKPFDPDLKLGPPSEEDYPQPSSPK >KAF4012197.1 hypothetical protein G4228_003071 [Cervus hanglu yarkandensis] VLSLSCLPSPCSAFSPVSAMEPLGL---------------------QEPGGQIAPKKAPGRRLAQAMTFTTDLFSLVAPNLILSPLSVALALSHVALGAQNQTLQRLKQVLHADSGPCLPHLLSHLCPGAFRLAARMYLQKGFPIKEDFLEQSEQLFGSKPMSLTGRKGEDLANINQWVKEATEGKIEDFLSDLPDDTVLLLLNAIHFQGFWRSKFDPNLTQRGTFHLDEQFTVPVDMMQALTYPLHWFLLEQPEIQVAHFPFKNNMSFVVLMPTEWNVSQVLANLTWDILHPSLRERPTKVQLPKLRLKYQLDLVATLSQLGLQELFQPDLRGISDRLVVSSVQHQSALELSEAGVEAAAATSTAMSRMSLSSFIVNRPFLFFILEDSMSLPLFVGSVRNPNPGAQPERKEQQDSPDGRDHKGLPRGDKPFDPDLKLGPPSEEDYPQPSSPK >XP_018101643.1 alpha-2-antiplasmin isoform X4 [Xenopus laevis] LLCLIVLSGIN--GSSAYTTEVPEDKNVTTQHYETTSIPE-----DLEEGADEKHPSEDNRKFSQAISFSIDLLKEIDPSAVMSPFSIALGLLQLSLGAGKEMQDKLMETLHVESLHCLHNKLKTVRTSILRTATRIYLKKGFQIKKSFLKRSEKWYGSKPMNLASKKKQNLDSINKWVKDVTEGQIPHFLSDLPQNVALILLNAMHFKGIWKNTFDPSLTSEEIFYINDDVGVPVEMMSAQKYPFSWFYLDGIEGHVAKLQFKGNMSFVILMPFTWNLSKLLANFNQSDLYRFPKEKASNLKMPKLNLDYKLELNEALTNLGLGQLFTPDLSGITNPLFVSSIQHQSSLELNEEGVEASAATAVMTSR-SHSVFRINRPFIFFLFEDTMGLPLFMGQVRDPSSGYQKKSSSK----DKKN----------------------------FLPK
PhyML tree of selected proteins (tr_F1RAP6_F1RAP6_DANRE_Serpin_peptidase_inhibitor__clade_F__alpha_2_antiplasmin__pigment_epithelium_derived_factor___member_2b_OS_Danio_rerio_OX_7955_GN_serpinf2b_PE_3_SV_1:0.43332931,(((((XP_002826863_1_alpha_2_antiplasmin_isoform_X1__Pongo_abelii_:0.01653489,(XP_018868995_1_alpha_2_antiplasmin_isoform_X2__Gorilla_gorilla_gorilla_:0.00226201,(sp_P08697_2_A2AP_HUMAN_Isoform_2_of_Alpha_2_antiplasmin_OS_Homo_sapiens_OX_9606_GN_SERPINF2:0.00761247,(sp_P08697_A2AP_HUMAN_Alpha_2_antiplasmin_OS_Homo_sapiens_OX_9606_GN_SERPINF2_PE_1_SV_3:0.00225983,(XP_016786642_1_alpha_2_antiplasmin_isoform_X2__Pan_troglodytes_:0.00000001,XP_003816899_2_alpha_2_antiplasmin_isoform_X2__Pan_paniscus_:0.00000001):0.00000001):0.00000001):0.00227436):0.00909762):0.07281674,((XP_008268885_1_PREDICTED__alpha_2_antiplasmin_isoform_X1__Oryctolagus_cuniculus_:0.07333585,(NP_032904_1_alpha_2_antiplasmin_precursor__Mus_musculus_:0.07001197,NP_001011892_1_alpha_2_antiplasmin_precursor__Rattus_norvegicus_:0.07226738):0.14994681):0.02192687,((XP_005624992_1_alpha_2_antiplasmin_isoform_X1__Canis_lupus_familiaris_:0.05538314,XP_006940042_1_alpha_2_antiplasmin_isoform_X2__Felis_catus_:0.04210466):0.03154793,(XP_020923238_1_alpha_2_antiplasmin__Sus_scrofa_:0.07335634,((NP_777095_1_alpha_2_antiplasmin_precursor__Bos_taurus_:0.04168656,(XP_020765465_1_alpha_2_antiplasmin_isoform_X1__Odocoileus_virginianus_texanus_:0.0048716,((KAB0367107_1_hypothetical_protein_FD755_020431__Muntiacus_reevesi_:0.00000001,KAB0366160_1_hypothetical_protein_FD754_010316__Muntiacus_muntjak_:0.00000001):0.00432818,(KAF4012197_1_hypothetical_protein_G4228_003071__Cervus_hanglu_yarkandensis_:0.00000001,(XP_043334282_1_alpha_2_antiplasmin_isoform_X2__Cervus_canadensis_:0.00227816,XP_043759289_1_alpha_2_antiplasmin_isoform_X2__Cervus_elaphus_:0.00000001):0.00000001):0.00251617):0.00454319):0.01044265):0.00887375,(XP_005693371_2_PREDICTED__alpha_2_antiplasmin_isoform_X1__Capra_hircus_:0.00000001,XP_004012597_3_alpha_2_antiplasmin_isoform_X2__Ovis_aries_:0.00458021):0.00853677):0.05384714):0.01577556):0.02594192):0.02337111):0.45672302,((XP_024997830_2_alpha_2_antiplasmin__Gallus_gallus_:0.11970811,XP_005502065_1_alpha_2_antiplasmin_isoform_X1__Columba_livia_:0.14333679):0.17878895,(XP_006032910_1_alpha_2_antiplasmin__Alligator_sinensis_:0.00600149,XP_006260669_2_PREDICTED__alpha_2_antiplasmin__Alligator_mississippiensis_:0.01064954):0.23933734):0.15868545):0.18518581,(XP_040194310_1_alpha_2_antiplasmin__Rana_temporaria_:0.43497931,XP_018101643_1_alpha_2_antiplasmin_isoform_X4__Xenopus_laevis_:0.48197906):0.21071224):0.22072481,(XP_039269246_1_serpin_B9_like__Styela_clava_:1.2628967,((XP_031557330_1_leukocyte_elastase_inhibitor_like__Actinia_tenebrosa_:0.64797887,(XP_006572060_1_leukocyte_elastase_inhibitor__Apis_mellifera_:1.49306938,NP_001122924_1_SERPIN_domain_containing_protein__Caenorhabditis_elegans_:1.35498835):0.20095306):0.15766839,(XP_038050239_1_leukocyte_elastase_inhibitor_like__Patiria_miniata_:0.66331453,(XP_030848953_1_leukocyte_elastase_inhibitor_like__Strongylocentrotus_purpuratus_:0.69596252,NP_524956_2_serpin_38F__isoform_A__Drosophila_melanogaster_:1.28751529):0.16885422):0.10753672):0.21971129):1.05657905):0.41913318,(XP_030249187_1_alpha_2_antiplasmin__Sparus_aurata_:0.10410236,(XP_015806684_1_PREDICTED__alpha_2_antiplasmin__Nothobranchius_furzeri_:0.17228875,XP_004075378_1_alpha_2_antiplasmin_isoform_X1__Oryzias_latipes_:0.13765955):0.02658296):0.29425184);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)