PB0158

DATABASE

Click here to access PB0158 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0158	O95841	Angiopoietin-related protein 1	ANGPTL1	ANG3, ANGPT3, ARP1, AngY, UNQ162, dJ595C2.2	Homo_sapiens

Domains	Gene Ontology
PF00147 (Fibrinogen_C)	GO:0005102 (enables) signaling receptor binding GO:0007169 (involved in) transmembrane receptor protein tyrosine kinase signaling pathway GO:0005615 (is active in) extracellular space GO:0062023 (is active in) collagen-containing extracellular matrix GO:0005576 (located in) extracellular region GO:0070062 (located in) extracellular exosome

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|O95841|ANGL1_HUMAN Angiopoietin-related protein 1 OS=Homo sapiens OX=9606 GN=ANGPTL1 PE=2 SV=1 MKTFTWTLGVLFFLLVDTGHCRGGQFKIKKINQRRYPRATDGKEEAKKCAYTFLVPEQRI TGPICVNTKGQDASTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLR KESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYA SLTDLVNNQSVMITLLEEQCLRIFSRQDTHVSPPLVQVVPQHIPNSQQYTPGLLGGNEIQ RDPGYPRDLMPPPDLATSPTKSPFKIPPVTFINEGPFKDCQQAKEAGHSVSGIYMIKPEN SNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLS NQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTT LDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSL RAVQMMIKPID >tr|Q5KQU0|Q5KQU0_DANRE Angiopoietin-like 1 OS=Danio rerio OX=7955 GN=angptl1a PE=2 SV=1 MRGVTWCMGTMLYLCISLLGKSHSGTELLHSRQRRAPADDSKKCSYTFLMPQQKITGPIC ASATGPEPDKDRVTRMDISDVREILSKQRREIEMLQLVADVDGNLVNEMKLLRKESRNMN SRVTQLYMQLLHEIIRKRDNSLELAQLENRVLNVTTEMLRLASRYKELEMRFAGLAGTVN NQSVLIAALEERCLRGYGRQDLPAVPPLVQVVPESIPANNNRFTNEIQRDNNNRAFPRGS RMDTPTPDPLGIPPPPQGTLTADGPFKDCSQVRQAGHSTSGMYLLKAEGSDRLIQAWCEH KLDNGGWTVFQRRKDGSVNFFRNWENYKKGFGNIDGEHWLGLENIYNLAKQGDYKLLVEL EDWVGKKVYAEYSSFHLEPESEGFRLRLGTYQGNAGDSLTSHNGKPFTTLDRDKDAFTGN CAHFHKGGWWYNACGQTNLNGVWYSGGVYRSKFQDGIFWAEYGGGYYSLKSVRMMIRPID
Selected proteins from model organisms >sp|O95841|ANGL1_HUMAN Angiopoietin-related protein 1 OS=Homo sapiens OX=9606 GN=ANGPTL1 PE=2 SV=1 MKTFTWTLGVLFFLLVDTGHCRGGQFKIKKINQRRYPRATDGKEEAKKCAYTFLVPEQRI TGPICVNTKGQDASTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLR KESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYA SLTDLVNNQSVMITLLEEQCLRIFSRQDTHVSPPLVQVVPQHIPNSQQYTPGLLGGNEIQ RDPGYPRDLMPPPDLATSPTKSPFKIPPVTFINEGPFKDCQQAKEAGHSVSGIYMIKPEN SNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLS NQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTT LDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSL RAVQMMIKPID >tr|Q5KQU0|Q5KQU0_DANRE Angiopoietin-like 1 OS=Danio rerio OX=7955 GN=angptl1a PE=2 SV=1 MRGVTWCMGTMLYLCISLLGKSHSGTELLHSRQRRAPADDSKKCSYTFLMPQQKITGPIC ASATGPEPDKDRVTRMDISDVREILSKQRREIEMLQLVADVDGNLVNEMKLLRKESRNMN SRVTQLYMQLLHEIIRKRDNSLELAQLENRVLNVTTEMLRLASRYKELEMRFAGLAGTVN NQSVLIAALEERCLRGYGRQDLPAVPPLVQVVPESIPANNNRFTNEIQRDNNNRAFPRGS RMDTPTPDPLGIPPPPQGTLTADGPFKDCSQVRQAGHSTSGMYLLKAEGSDRLIQAWCEH KLDNGGWTVFQRRKDGSVNFFRNWENYKKGFGNIDGEHWLGLENIYNLAKQGDYKLLVEL EDWVGKKVYAEYSSFHLEPESEGFRLRLGTYQGNAGDSLTSHNGKPFTTLDRDKDAFTGN CAHFHKGGWWYNACGQTNLNGVWYSGGVYRSKFQDGIFWAEYGGGYYSLKSVRMMIRPID >NP_082609.2 angiopoietin-related protein 1 precursor [Mus musculus] MKAFVWTLSVLLFLLGSGHCKGGQLKIKKITQRRYPRATDGKEEAKKCSYTFLVPEQKITGPICVNTKGQ DAGTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEI IRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVTITVLEEQCLRMFSRQDPHA SPPLVQVVPRHSPNSHQYTPGLLGGNEIQRDPGYPRDVMPPPDLPTAPTKSPFKIPAVTFINEGPFKDCQ QAKEAGHSASGIYMIKPENSNGLMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWL GLDNIYKLSNQDNYKLMIELEDWSEKKVYAEYSSFRLEPESDYYRLRLGTYQGNAGDSMMWHNGKQFTTL DRDKDTYTGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPID >XP_024831936.1 angiopoietin-related protein 1 isoform X1 [Bos taurus] MQKDSIQPHFKMKAFIWTLSVLFFLLMGIGHGRGRQFKIKKITQRRYPRATDGKEDAKKCSYTFLVPEQK ITGPICVNTKGQDAGTIKDMITRMDLENLKDVLSKQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSR VTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQ CLRIFSRQDPHVSPPLVQVVPQHIPNSHQYTPGLLGGNEIQRDPGYPRDLMPPPDLVTSPTKSPLKIPPV TFINEGPYKDCQHAKDAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYK KGFGNIDGEYWLGLENIYLLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDS MMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYS LRAVQMLIKPID >XP_038526496.1 angiopoietin-related protein 1 isoform X1 [Canis lupus familiaris] MHKDFIQPHFKMKAFIWTLSALFFLLMGIGHCRGGQFKMKKITQRRYPRATDAKEEAKKCAYTFLVPEQK ITGPICVNTKGQDASMIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSR VTQLYMQLLHEIIRKRDNSLELSQLENKILNITTEMLKMATRYKELEVKYASLTDLVNNQSVMITLLEEQ CLKIFSRQDPHVSPPLVQVVPQHIPNSHQYTPGLLGGNEIQRDPGYPRDLMPPPDLGTSPTKSPFKIPPV TFINEGPFKDCQHAKEAGHSVSGIYMIKPENSNGPIQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYK KGFGNIDGEYWLGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFFRLRLGTYQGNAGDS MMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYS LRAVQMMIKPID >NP_001102853.1 angiopoietin-related protein 1 precursor [Rattus norvegicus] MKTFVWILSVVLFLLGIGHCKGGQFKIKKTTQRRYPRATDGKEETKKCSYTFLVPEQKITGPICVNTKGQ DAGTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEI IRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITVLEEQCLRLFSRQDPHV SPPLVQVVPRHIPNSHQDTPGLLAGNEIQRDPGYPRDLMPPPDLATAPTKSPFKIPAVTFINEGELPFPG QWKNEAAMLYNPCDNTLRTS >XP_001155579.1 angiopoietin-related protein 1 [Pan troglodytes] MKAFTWTLGVLFFLLVDAGHCRGGQFKIKKINQRRYPRATDGKEEAKKCAYTFLVPEQRITGPICVNTKG QDASTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHE IIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDTH VSPPLVQVVPQHIPNSHQYTPGLLGGNEIQRDPGYPRDLMPPPDLATSPTKSPFKIPPVTFINEGPFKDC QQAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYW LGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTT LDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPI D >NP_001264594.1 angiopoietin-related protein 1 precursor [Gallus gallus] MKILKWTLGMLLFLLLSIGRCTEPSTLNKTSQRRHPRSTDGGEEGRKCGYTFLVPEQKITGPICVNNEPG TGNRKDEVTRMDIENLKDVLSKQKREIDILQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEII RKRDNSLELSQLENKVLNVTTEMLKMATKYKELEVKYAALTDLVNNQSVIISLLEEQCLRIFSRQDTHGS PPLVQVVPQHIPNSQPYTPVLLGGNEIQRDPGYPRDRDVRPPPDPATSPTKSPFRVPPLALINEGPFKDC QHAKDAGYSNSGIYMIKAENSNEPMQLWCENSLDPGGWAVIQKRTDGSVNFFRNWDSYKKGFGNIDGEYW LGLENIYMLTNQDNYRLLIELEDWSNKKVYAEYSSFRLEPENEFYRLRLGTYQGNAGDSMIWHNGKQFTT LDRDRDMYSGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLKAVQMMIRPI D >XP_005667844.1 angiopoietin-related protein 1 isoform X1 [Sus scrofa] MQKDVIHAHCKMKALIWTLSVLFFLLMGIGQCRGGQFKIKKITQRRYPRATDGKEEVKKCAYTFLVPEQK ITGPICVNTKGQDAGTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSR VTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQ CLRIFSRQDPHLSPPLVQVVPQHIPNSHQYTPGLLGGNEIQRDPGYPRDLMPPPDLATPPTKSPFKIPPV TFINEGPFKDCQHAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYK KGFGNTDGEYWLGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDS MMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSRYQDGIFWAEYRGGSYS LRAVQMMIKPID >XP_002715049.1 PREDICTED: angiopoietin-related protein 1 [Oryctolagus cuniculus] MKAFIWTAGVLIFLLIGTGHCRGGQFKIKKMTQRRYPRATDGKEEVKKCSYTFLVPEQKITGPICVNTKG QDAGAMKDMVTRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHE IIRKRDNSLELSQLENKVLNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITVLEEQCLRIFSRQDTH VSPPLVQVVPQHIPNSHQYTPGLLGGNEIQRDPGYPRDLMPPPDLATSPTKSPFKMPPVTFINEGPFKDC QQAKEAGHSISGIYLIKPENSNGPMQLWCENSLDPGGWTVIQKRKDGSVNFFRNWENYKKGFGNIDGEYW LGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEYYRLRLGTYQGNAGDSLMWHNGKQFTT LDRDKDVYTGNCAHFHKGGWWYNTCAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPI D >XP_002809805.1 angiopoietin-related protein 1 [Pongo abelii] MKAFTWTLGVLFFLLVDAGHCRGGQFKIKKINQRRYPRATDGKEEAKKCAYTFLVPEQRITGPICVNTKG QDASTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHE IIRKRDNSLELSQLENKILNVTTEMLRMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDTH VSPPLVQVVPQHIPNSHQYTPGLLGGNEIQRDPGYPRDLMPPADLATSPTKSPFKIPPVTFINEGPFKDC QQAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYW LGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTT LDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPI D >XP_003824749.1 angiopoietin-related protein 1 [Pan paniscus] MKAFTWTLGVLFFLLVDAGHCRGGQFKIKKINQRRYPRATDGKEEAKKCAYTFLVPEQRITGPICVNTKG QDASTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHE IIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDTH VSPPLVQVVPQHIPNSHQYTPGLLGGNEIQRDPGYPRDLMPPPDLATSPTKSPFKIPPVTFINEGPFKDC QQAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYW LGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTT LDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPI D >XP_003999280.1 angiopoietin-related protein 1 [Felis catus] MHKDFIQPHFKMKAFIWTLSVLFFLLMGIGHCRGGQFKIKKITQRRYPRATDGKEEAKKCSYTFLVPEQK ITGPICVNTKGQDASTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSR VTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQ CLKIFSRQDPHVSPPLVQVVPQHIPNSHPYTPGLLGGNEIQRDPGYPRDLMPLPDLGTSSTKSPLKIPPV TFINEGPFKDCQHAKEAGHSVSGIYMIKPENSNGPIQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYK KGFGNIDGEYWLGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFFRLRLGTYQGNAGDS MMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYS LRAVQMMIKPID >XP_004013880.1 angiopoietin-related protein 1 [Ovis aries] MQKESIQPHFKMKAFIWTLSVLFFLLMGIGHCRGGQFKIKKITQRRYPRATDGKEEAKKCSYTFLVPEQK ITGPICVNTKGQDAGTIKDMITRMDLENLKDVLSKQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSR VTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQ CLRIFSRQDPHVSPPLVQVVPQHTPHSHQYTPGLLGGNEIQRDPGYPRDLMPPPDLSTSPTKSPLKIPPV TFINEGPYKDCQHAKDAGHSVSGIYLIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYK KGFGNIDGEYWLGLENIYLLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDS MMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYS LRAVQMLIKPID >XP_004028013.1 angiopoietin-related protein 1 [Gorilla gorilla gorilla] MKAFTWTLGVLFFLLVDAGHCRGGQFKIKKINQRRYPRATDGKEEAKKCAYTFLVPEQRITGPICVNTKG QDASTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHE IIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDTH VSPPLVQVVPQHIPNSHQYTPGLLGGNEIQRDPGYPRDLMPPPDLATSPTKSPFKIPPVTFINEGPFKDC QQAKEAGHSVSGIYMIKPQNSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNTDGEYW LGLENIYMLSNQDNYKLLIELEDWSDKKVYAQYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTT LDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPI D >XP_004068226.1 angiopoietin-related protein 1 [Oryzias latipes] MQGLVWSLCVLLCLSLWEESSCRSSRETQRTKEPFLKRSKRAPTDPNAKQCSYTFLVPEQRITGPICAST TGPEPDKDRVTRMDIADVREVLNKQRREIETLQLVVDVDGNLVNEMKLLRKESRNMNSRVTQLYMQLLHE IIRKRDNSLELAQLENRVLNVTSEMMRLASRYKDLEARFATIAGVVNNQSVLITALEEQCLRSLGQGERA QAPPLVRAVPQNIPVDNRFTNEIQRNSRAFTRGSRKNSPTVSPFGIDPPPPQGTLTSDGPFKDCYEVRQA GHTTSGMYLLKTDNSDRLFQAWCEHGLDNGGWTVLQRRRGGAINFFRNWDTYKKGFGNIDGEHWLGLENI YNLSKQGDYKLMIELEDWAGKKVYAEYSSFHLESENQGYRLRLGTYQGNAGDSLSSNNGKQFTTLDRDRD AFSGNCAHFHRGGWWYNDCGQTNLNGVFHSGGVYRSKFQDGIFWADYGGGFYSLKSVLLMIRPID >XP_005501145.1 angiopoietin-related protein 1 [Columba livia] MKIFKWTWGVLLFLLLSIGRCTEQSTPNKTSQRRHPRSADGGEEGKKCGYTFLVPEQKITGPICVNTNGP ATGNRKDEVTRMDIENLKDVLSKQKREIDILQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEI IRKRDNSLELSQLENKVLNVTTEMLKMATKYKELEVKYAALTDLVNNQSVTISLLEEQCLRIFSRQDTHG SPPLVQVVPQHIPNSQPYSPVLLGGNEIQRDPAYPRDRDVRPPPDPATSPTKSPFRVPPLALINEGPFKD CQQAKEAGHSNSGIYMIKPENSNEPMQLWCENSLDPGGWAVIQKRTDGSVNFFRNWDSYKKGFGNIDGEY WLGLENIYMLTNQDNYRLLIELEDWSNKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMIWHNGKQFT TLDRDRDMYSGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLKAVQMMIRP ID >XP_005690975.1 PREDICTED: angiopoietin-related protein 1 [Capra hircus] MQKESIQPHFKMKAFIWTLSVLFFLLMGIGHCRGGQFKIKKITQRRYPRATDGKEEAKKCSYTFLVPEQK ITGPICVNTKGQDAGTIKDMITRMDLENLKDVLSKQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSR VTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQ CLRIFSRQDPHVSPPLVQVVPQHIPHSHQYTPGLLGGNEIQRDPSYPRDLMPPPDLLTSPTKSPLKIPPV TFINEGPYKDCQHAKDAGHSVSGIYLIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYK KGFGNIDGEYWLGLENIYLLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDS MMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYS LRAVQMLIKPID >XP_006033079.1 angiopoietin-related protein 1 [Alligator sinensis] MKIFTWTLGMVLFLLLSTGHCREQAALNKVSQKRHPRSTDGGEEGKKCGYTFLVPEQKITGPICVNTNGP RSDNRKDEVTRMDIENLKDVLSKQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEI IRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYAALTDLVNNQSVIISLLEEQCLRVFSRQDTHG SPPLVQVVPQHIPNSQPYTPVLLGGNEIQRDPGYPRDRDVRPPPDPATSPTKSPFRIPPLALINEGPFKD CQQAKEAGYSNSGIYMIKPENSNEPMQLWCENSLDPGGWAVIQKRTDGSVNFFRNWDSYKKGFGNVDGEY WLGLENIYMLTNQDNYRLLIELEDWSNKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMIWHNGKQFT TLDRDRDMYTGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLKAVQMMIRP ID >XP_006267321.1 PREDICTED: angiopoietin-related protein 1 [Alligator mississippiensis] MKIFTWTLGMVLFLLLSTGHCREQAALKVSQKRHPRSTDGGEEGKKCGYTFLVPEQKITGPICVNTNGPR SDNRKDEVTRMDIENLKDVLSKQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEII RKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYAALTDLVNNQSVIISLLEEQCLRVFSRQDTHGS PPLVQVVPQHIPNSQPYTPVLLGGNEIQRDPGYPRDRDVRPPPDPATFPTKSPFRIPPLALINEGPFKDC QQAKEAGYSNSGIYMIKPENSNEPMQLWCENSLDPGGWAVIQKRTDGSFNFFRNWDSYKKGFGNVDGEYW LGLENIYMLTNQDNYRLLIELEDWSNKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMIWHNGKQFTT LDRDRDMYTGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLKAVQMMIRPI D >XP_015827157.1 PREDICTED: angiopoietin-related protein 1-like [Nothobranchius furzeri] MQGLIWSLCALLCLSLWEESHCRSSRNIRSVNEPSLLRTKRALQDTDAKKCSYTFLVPEQRITGPICAST TGPEPDKDRVTRMDISDVREVLNKQRREIETLQLVVEVDGNLVNEMKLLRKESRNMNSRVTQLYMQLLHE IIRKRDNSLELVQLENRVLNVTSEMMRLASRYKELEARFATMAGVVNNQSILISALEEQCLRTLGRSELP PVPPLVQVVPENIPIDNRFTNEIVTKNQAFSRASRRESPTRSPFGMDPPPPQGTLTSDGPFKDCYQVRQA GYTTSGMYLLKTDNSEQLIQAWCEHGLDNGGWTVLQRRRDGSVNFFRNWENYKKGFGNIDGEHWLGLQNI FNLAKQGDYRLMIELEDWAGKKVYAEYSSFHLESESEGYKLRLGTYQGNAGDSFSSNNGKAFTTLDRDKD TFSGNCAHYHKGGWWYNACGQTNLNGVWYSGGVYRSKFQDGIFWADYGGGFYSLKCVRLMIRPID >XP_020724522.1 angiopoietin-related protein 1 [Odocoileus virginianus texanus] MQKDSIQPHFKMKAFIWTLSVLFFLLMGIGHCRGGQFKIKKITQRRYPRATDGKEEAKKCSYTFLVPEQK ITGPICVNTKGQDAGTIKDMITRMDLENLKDVLSKQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSR VTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQ CLRIFSRQDPHVSPPLVQVVPQHIPNSHQYTPGLLGGNEIQRDPGYPRDLMPPSDLITSPTKSPLKIPPV TFINEGPYKDCQHAKDAGHSVSGIYMIKPENSKGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYK KGFGNIDGEYWLGLENIYLLSNQDNYKLLIELEDWSEKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDS MMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYS LRAVQMLIKPID >XP_030290205.1 angiopoietin-related protein 1 [Sparus aurata] MQGLMWSLCALLCLSLWEESYCRSSREARRTKVPSLHRSKRAPLDPNAKKCSYTFLVPEQRITGPICAST TGPEPDKDRVTRMDIADVREVLSKQRREIETLQLVVDVDGNLVNEMKLLRKESRNMNSRVTQLYMQLLHE IIRKRDNSLELAQLENRVLNVTSEMMRLASRYKELESRYATMAGVVNNQSILISALEEQCMRTLGRSELP VVPPLVQVVPQNIPVNNRFTNEIQRYNNNRAFPRGSRMETPTASPFGIDPPPPQGTLTSDGPFKDCFQVR QAGHATSGMYLLKTDANDRLIQAWCEHGLDNGGWTVLQRRKDGSVNFFRNWENYKKGFGNIDGEHWLGLD NIYNLGKQGDYKLMVELEDWTGKKVYAEYSSFHLESESEGYRLRLGTYQGNAGDSFSSHNGKQFTTLDRD KDAFSGNCAHFHKGGWWYNACGQTNLNGVWYSGGVYRSKFQDGIFWADYGGGFYSLKSVRLMIRPID >XP_040216274.1 angiopoietin-related protein 1 isoform X1 [Rana temporaria] MKSCLDSSLDRIEMDTTLWTLKVLLLSLFTAGHCAKSKLGSQSGTSIRLARSTDYAENNDGKKCGYTFLV PQQKITGPICVSTKGPGANKDQVTRMDLENVKDSLTKQRREMEMLQVLVDVDGNIVSEVKLLRKESRNMN SRVTQLYMQLLHEIIRKRDNSLEIAQLENRILNVTAEMLRAATRYKELEVKYASLVDLVNNQSAIITLLE EQCMSVFSRRDSQGSPPLVQVVPQHIPNSKPYTPGLAGGNEIQRDTGYPRARDSRQPPQAPVPTVSPFRV PPVTVINEGPFKDCKHARESGFTSSGIYLIKPTNANSPMQLWCENNLDPGGWAVIQRRIDGSANFFRNWE TYKKGFGNIDSEYWLGLENIYQLSNQDNYKLLIELEDWNNKKVYAEYSSFRLEPETDFYRLRLGTYQGNA GDSMVWHNGKQFTTLDRDRDMYTGNCAHFHKGGWWYNACAHANLNGVWYRGGVYRSKHQDGIYWAEYRGG SYSLKKVQMMIRPID >KAB0341181.1 hypothetical protein FD754_018107 [Muntiacus muntjak] MQFNSIQPHFKMKAFIWTLSVLFFLLMGIGHCRGGQFKIKKITQRRYPRATDGKEEAKKCSYTFLVPEQKITGPICVNTK GQDAGTIKDMITRMDLENLKDVLSKQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSL ELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDPHVSPPLVQVVPQHIPNSHQY TPGLLGGNEIQRDPGYPRDLMPPPDLVTSPTKSPLKIPPVTFINEGPYKDCQHAKDAGHSVSGIYMIKPENSKGPLQLWC ENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYLLSNQDNYKLLIELEDWSDKKVYAEYSSFRLE PESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKYQDGIF WAEYRGGSYSLRAVQMLIKPID >XP_043341746.1 angiopoietin-related protein 1 isoform X1 [Cervus canadensis] MQKDSIQPHFKMKAFIWTLSVLFFLLMGIGHCRGGQFKIKKITQRRYPRATDGKEEAKKCSYTFLVPEQKITGPICVNTK GQDAGTIKDMITRMDLENLKDVLSKQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSL ELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDPHVSPPLVQVVPQHIPNSHQY TPGLLGGNEIQRDPGYPRGLMPPPDLVTSPTKSPLKIPPVTFINEGPYKDCQHAKDAGHSVSGIYMIKPENSKGPMQLWC ENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYLLSNQDNYKLLIELEDWSDKKVYAEYSSFRLE PESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGQYRSKYQDGIF WAEYRGGSYSLRAVQMLIKPID >XP_043779981.1 angiopoietin-related protein 1 isoform X1 [Cervus elaphus] MQKDSIQPHFKMKAFIWTLSVLFFLLMGIGRCRGGQFKIKKITQRRYPRATDGKEEAKKCSYTFLVPEQKITGPICVNTK GQDAGTIKDMITRMDLENLKDVLSKQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSL ELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDPHVSPPLVQVVPQHIPNSHQY TPGLLGGNEIQRDPGYPRGLMPPPDLVTSPTKSPLKIPPVTFINEGPYKDCQHAKDAGHSVSGIYMIKPENSKGPMQLWC ENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYLLSNQDNYKLLIELEDWSDKKVYAEYSSFRLE PESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGQYRSKYQDGIF WAEYRGGSYSLRAVQMLIKPID >XP_018113986.1 angiopoietin-related protein 1 [Xenopus laevis] MDTTLWNLGLMLFLVVPTGLCSNSDTKSRRQTLTRIARSTDEVDDGKRCGYTFLVPQQKVTGPICVLTKGSGPNKELVTR MDLENVKDVLAKQRRDMEMLQVVVAVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNALEVSQLETKILNVT SEMLRAATRYKELELKYASLVDVVNNQSSVIALLEEQCMKVFSRRDSPGSPPLVQVVPQHYPQIHQYTPGLGGGNEIQRD TGYPRVRDSRQPPQAPTSSPFRIPPVTIIDEGPFRDCQHAKESGFSSSGIYLIKPDNANSPMQLWCENSLDPGGWAVIQR RTDGSANFFRNWETYKKGFGNIDAEYWLGLENIYQLTNQDNYRLLIELEDWSNKKVYAEYSSFRLEPESEFYKLRLGTYQ GNAGDSMVWHNGKQFTTLDRDKDMYSGNCAHFHKGGWWYNACAHANLNGVWYRGGHYRSKHQDGIYWAEYRGGSYSLKAV QMLIRPID >XP_003211422.1 angiopoietin-related protein 2 [Meleagris gallopavo] MMTTKFICLMLIAAVGTAASKTQEFEDNDEEREQEFIYMNRYKRSSDPQDKCTYTFIVPQQRVTGAICVNSKEPEVLLEN RVNKQELQLLNNELLKQKRQIETLQQLVEVDGGIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNALELSQLENKI LNQTADMLQLANKYKDLEYKYQHLMSIANNQSVIINQLEEYCQRMPSIKPLPQTPQPPSKVYQPPTYNRMINQISTNEIQ SDQNLKVLPPTLPTMPAVTSIPTSTDKPSGPWRDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRL DGSVNFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLITMEDWSGRKVFAEYASFRLEPESEYYKLRLGRYNGN AGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNGVWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVM MIRPNPNTFH >XP_039268423.1 angiopoietin-related protein 2-like [Styela clava] MSRIVVVTLFIALLFCGHVRSQLTVVDPPIMQIATGGDNNGKSNMKYDVKIRKYTVVRVPETPPSTTTEISTTTTTPPPD LDVNHIEVQTRSTFEENLLEEDHDCAFTFTLPNPRPSNQQVCVRDVRALMTSYPEERRSGDEEALNTLRNEISLWQESMG DLKTQIEERLAVPSLEPVRNDVRLLQKESRNMNFRISQLYMQLLHEIIRKRDDTIEYTSVENSVMNVTIKYYELKEKHEA LVTDHKALKQQSQSQQEQIKILQTKMEEMVHRMNRMAVDIQLMGIDDEKDEVNDTANSSLSESRSSYTNCVDIQLYASKE SGIYILTLPSLSRKMKVWCDFEQDPGGWTVIQRRSEGKVNFYRNFASYQRGFGSLEGEFWLGLENIHHLTNQPGVNYKLH IDMEDWSGRKTFVEYGSFKLEGQDEGYRLKVAHYSGTAGDSLTWHNNMKFTTKNVDNDPFARNCANYQKGGWWYNTCAHS NLNGVYYMGGHYRSKFQDGIYWSEWRGGSYSLKHVEMKIKPSE
Mafft alignment of selected proteins >sp|O95841|ANGL1_HUMAN Angiopoietin-related protein 1 OS=Homo sapiens OX=9606 GN=ANGPTL1 PE=2 SV=1 -------------MKTFTWTLGVL--FFL-LVDTGHCRGG-------------------- -----QFKIKK---------------------------------INQRRYPRATD--GKE EAKKCAYTFLVPEQRITG-PICVN------TKGQDASTIKDM----ITRMDLENLKDVLS RQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQ LENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDTHVSP PLVQVVPQHIPN-SQQYTPGLLGGNEIQRDPGYP--RDLMPPPDLATSPTKSPFKI---- PPVTFINEGPFKDCQQAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTD GSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSNQD--NYKLLIELEDWSDKKVYAEYS SFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNA CAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPID---- >tr|Q5KQU0|Q5KQU0_DANRE Angiopoietin-like 1 OS=Danio rerio OX=7955 GN=angptl1a PE=2 SV=1 -------------MRGVTWCMGTMLYLCISLLGKSH------------------------ ----------S---------------------------------GTELLHSRQRRAPAD- DSKKCSYTFLMPQQKITG-PICAS------ATGPEPD--KDR----VTRMDISDVREILS KQRREIEMLQLVADVDGNLVNEMKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELAQ LENRVLNVTTEMLRLASRYKELEMRFAGLAGTVNNQSVLIAALEERCLRGYGRQDLPAVP PLVQVVPESIPANNNRFT------NEIQRDNNNR----AFPRGSRMDTPTPDPLGI-PPP PQGTLTADGPFKDCSQVRQAGHSTSGMYLLKAEGSDRLIQAWCEHKLDNGGWTVFQRRKD GSVNFFRNWENYKKGFGNIDGEHWLGLENIYNLAKQG--DYKLLVELEDWVGKKVYAEYS SFHLEPESEGFRLRLGTYQGNAGDSLTSHNGKPFTTLDRDKDAFTGNCAHFHKGGWWYNA CGQTNLNGVWYSGGVYRSKFQDGIFWAEYGGGYYSLKSVRMMIRPID---- >NP_082609.2 angiopoietin-related protein 1 precursor [Mus musculus] -------------MKAFVWTLSVL--LFL-L-GSGHCKGG-------------------- -----QLKIKK---------------------------------ITQRRYPRATD--GKE EAKKCSYTFLVPEQKITG-PICVN------TKGQDAGTIKDM----ITRMDLENLKDVLS RQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQ LENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVTITVLEEQCLRMFSRQDPHASP PLVQVVPRHSPN-SHQYTPGLLGGNEIQRDPGYP--RDVMPPPDLPTAPTKSPFKI---- PAVTFINEGPFKDCQQAKEAGHSASGIYMIKPENSNGLMQLWCENSLDPGGWTVIQKRTD GSVNFFRNWENYKKGFGNIDGEYWLGLDNIYKLSNQD--NYKLMIELEDWSEKKVYAEYS SFRLEPESDYYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDTYTGNCAHFHKGGWWYNA CAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPID---- >XP_024831936.1 angiopoietin-related protein 1 isoform X1 [Bos taurus] MQK--DSIQPHFKMKAFIWTLSVL--FFL-LMGIGHGRGR-------------------- -----QFKIKK---------------------------------ITQRRYPRATD--GKE DAKKCSYTFLVPEQKITG-PICVN------TKGQDAGTIKDM----ITRMDLENLKDVLS KQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQ LENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDPHVSP PLVQVVPQHIPN-SHQYTPGLLGGNEIQRDPGYP--RDLMPPPDLVTSPTKSPLKI---- PPVTFINEGPYKDCQHAKDAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTD GSVNFFRNWENYKKGFGNIDGEYWLGLENIYLLSNQD--NYKLLIELEDWSDKKVYAEYS SFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNA CAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLRAVQMLIKPID---- >XP_038526496.1 angiopoietin-related protein 1 isoform X1 [Canis lupus familiaris] MHK--DFIQPHFKMKAFIWTLSAL--FFL-LMGIGHCRGG-------------------- -----QFKMKK---------------------------------ITQRRYPRATD--AKE EAKKCAYTFLVPEQKITG-PICVN------TKGQDASMIKDM----ITRMDLENLKDVLS RQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQ LENKILNITTEMLKMATRYKELEVKYASLTDLVNNQSVMITLLEEQCLKIFSRQDPHVSP PLVQVVPQHIPN-SHQYTPGLLGGNEIQRDPGYP--RDLMPPPDLGTSPTKSPFKI---- PPVTFINEGPFKDCQHAKEAGHSVSGIYMIKPENSNGPIQLWCENSLDPGGWTVIQKRTD GSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSNQD--NYKLLIELEDWSDKKVYAEYS SFRLEPESEFFRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNA CAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLRAVQMMIKPID---- >NP_001102853.1 angiopoietin-related protein 1 precursor [Rattus norvegicus] -------------MKTFVWILSVV--LFL-L-GIGHCKGG-------------------- -----QFKIKK---------------------------------TTQRRYPRATD--GKE ETKKCSYTFLVPEQKITG-PICVN------TKGQDAGTIKDM----ITRMDLENLKDVLS RQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQ LENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITVLEEQCLRLFSRQDPHVSP PLVQVVPRHIPN-SHQDTPGLLAGNEIQRDPGYP--RDLMPPPDLATAPTKSPFKI---- PAVTFINEGELPFPGQWK---------------NEAAMLYNPCDNTL----------RTS ------------------------------------------------------------ ------------------------------------------------------------ --------------------------------------------------- >XP_001155579.1 angiopoietin-related protein 1 [Pan troglodytes] -------------MKAFTWTLGVL--FFL-LVDAGHCRGG-------------------- -----QFKIKK---------------------------------INQRRYPRATD--GKE EAKKCAYTFLVPEQRITG-PICVN------TKGQDASTIKDM----ITRMDLENLKDVLS RQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQ LENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDTHVSP PLVQVVPQHIPN-SHQYTPGLLGGNEIQRDPGYP--RDLMPPPDLATSPTKSPFKI---- PPVTFINEGPFKDCQQAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTD GSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSNQD--NYKLLIELEDWSDKKVYAEYS SFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNA CAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPID---- >NP_001264594.1 angiopoietin-related protein 1 precursor [Gallus gallus] -------------MKILKWTLGML--LFL-LLSIGRCT-E-------------------- -----PSTLNK---------------------------------TSQRRHPRSTD--GGE EGRKCGYTFLVPEQKITG-PICVN-------NEPGTGNRKDE----VTRMDIENLKDVLS KQKREIDILQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQ LENKVLNVTTEMLKMATKYKELEVKYAALTDLVNNQSVIISLLEEQCLRIFSRQDTHGSP PLVQVVPQHIPN-SQPYTPVLLGGNEIQRDPGYPRDRDVRPPPDPATSPTKSPFRV---- PPLALINEGPFKDCQHAKDAGYSNSGIYMIKAENSNEPMQLWCENSLDPGGWAVIQKRTD GSVNFFRNWDSYKKGFGNIDGEYWLGLENIYMLTNQD--NYRLLIELEDWSNKKVYAEYS SFRLEPENEFYRLRLGTYQGNAGDSMIWHNGKQFTTLDRDRDMYSGNCAHFHKGGWWYNA CAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLKAVQMMIRPID---- >XP_005667844.1 angiopoietin-related protein 1 isoform X1 [Sus scrofa] MQK--DVIHAHCKMKALIWTLSVL--FFL-LMGIGQCRGG-------------------- -----QFKIKK---------------------------------ITQRRYPRATD--GKE EVKKCAYTFLVPEQKITG-PICVN------TKGQDAGTIKDM----ITRMDLENLKDVLS RQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQ LENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDPHLSP PLVQVVPQHIPN-SHQYTPGLLGGNEIQRDPGYP--RDLMPPPDLATPPTKSPFKI---- PPVTFINEGPFKDCQHAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTD GSVNFFRNWENYKKGFGNTDGEYWLGLENIYMLSNQD--NYKLLIELEDWSDKKVYAEYS SFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNA CAHSNLNGVWYRGGHYRSRYQDGIFWAEYRGGSYSLRAVQMMIKPID---- >XP_002715049.1 PREDICTED: angiopoietin-related protein 1 [Oryctolagus cuniculus] -------------MKAFIWTAGVL--IFL-LIGTGHCRGG-------------------- -----QFKIKK---------------------------------MTQRRYPRATD--GKE EVKKCSYTFLVPEQKITG-PICVN------TKGQDAGAMKDM----VTRMDLENLKDVLS RQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQ LENKVLNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITVLEEQCLRIFSRQDTHVSP PLVQVVPQHIPN-SHQYTPGLLGGNEIQRDPGYP--RDLMPPPDLATSPTKSPFKM---- PPVTFINEGPFKDCQQAKEAGHSISGIYLIKPENSNGPMQLWCENSLDPGGWTVIQKRKD GSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSNQD--NYKLLIELEDWSDKKVYAEYS SFRLEPESEYYRLRLGTYQGNAGDSLMWHNGKQFTTLDRDKDVYTGNCAHFHKGGWWYNT CAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPID---- >XP_002809805.1 angiopoietin-related protein 1 [Pongo abelii] -------------MKAFTWTLGVL--FFL-LVDAGHCRGG-------------------- -----QFKIKK---------------------------------INQRRYPRATD--GKE EAKKCAYTFLVPEQRITG-PICVN------TKGQDASTIKDM----ITRMDLENLKDVLS RQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQ LENKILNVTTEMLRMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDTHVSP PLVQVVPQHIPN-SHQYTPGLLGGNEIQRDPGYP--RDLMPPADLATSPTKSPFKI---- PPVTFINEGPFKDCQQAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTD GSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSNQD--NYKLLIELEDWSDKKVYAEYS SFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNA CAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPID---- >XP_003824749.1 angiopoietin-related protein 1 [Pan paniscus] -------------MKAFTWTLGVL--FFL-LVDAGHCRGG-------------------- -----QFKIKK---------------------------------INQRRYPRATD--GKE EAKKCAYTFLVPEQRITG-PICVN------TKGQDASTIKDM----ITRMDLENLKDVLS RQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQ LENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDTHVSP PLVQVVPQHIPN-SHQYTPGLLGGNEIQRDPGYP--RDLMPPPDLATSPTKSPFKI---- PPVTFINEGPFKDCQQAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTD GSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSNQD--NYKLLIELEDWSDKKVYAEYS SFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNA CAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPID---- >XP_003999280.1 angiopoietin-related protein 1 [Felis catus] MHK--DFIQPHFKMKAFIWTLSVL--FFL-LMGIGHCRGG-------------------- -----QFKIKK---------------------------------ITQRRYPRATD--GKE EAKKCSYTFLVPEQKITG-PICVN------TKGQDASTIKDM----ITRMDLENLKDVLS RQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQ LENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLKIFSRQDPHVSP PLVQVVPQHIPN-SHPYTPGLLGGNEIQRDPGYP--RDLMPLPDLGTSSTKSPLKI---- PPVTFINEGPFKDCQHAKEAGHSVSGIYMIKPENSNGPIQLWCENSLDPGGWTVIQKRTD GSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSNQD--NYKLLIELEDWSDKKVYAEYS SFRLEPESEFFRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNA CAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLRAVQMMIKPID---- >XP_004013880.1 angiopoietin-related protein 1 [Ovis aries] MQK--ESIQPHFKMKAFIWTLSVL--FFL-LMGIGHCRGG-------------------- -----QFKIKK---------------------------------ITQRRYPRATD--GKE EAKKCSYTFLVPEQKITG-PICVN------TKGQDAGTIKDM----ITRMDLENLKDVLS KQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQ LENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDPHVSP PLVQVVPQHTPH-SHQYTPGLLGGNEIQRDPGYP--RDLMPPPDLSTSPTKSPLKI---- PPVTFINEGPYKDCQHAKDAGHSVSGIYLIKPENSNGPMQLWCENSLDPGGWTVIQKRTD GSVNFFRNWENYKKGFGNIDGEYWLGLENIYLLSNQD--NYKLLIELEDWSDKKVYAEYS SFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNA CAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLRAVQMLIKPID---- >XP_004028013.1 angiopoietin-related protein 1 [Gorilla gorilla gorilla] -------------MKAFTWTLGVL--FFL-LVDAGHCRGG-------------------- -----QFKIKK---------------------------------INQRRYPRATD--GKE EAKKCAYTFLVPEQRITG-PICVN------TKGQDASTIKDM----ITRMDLENLKDVLS RQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQ LENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDTHVSP PLVQVVPQHIPN-SHQYTPGLLGGNEIQRDPGYP--RDLMPPPDLATSPTKSPFKI---- PPVTFINEGPFKDCQQAKEAGHSVSGIYMIKPQNSNGPMQLWCENSLDPGGWTVIQKRTD GSVNFFRNWENYKKGFGNTDGEYWLGLENIYMLSNQD--NYKLLIELEDWSDKKVYAQYS SFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNA CAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPID---- >XP_004068226.1 angiopoietin-related protein 1 [Oryzias latipes] -------------MQGLVWSLCVL--LCLSLWEESSCRSS-------------------- ------RETQR---------------------------------TKEPFLKRSKRAPTDP NAKQCSYTFLVPEQRITG-PICAS------TTGPEPD--KDR----VTRMDIADVREVLN KQRREIETLQLVVDVDGNLVNEMKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELAQ LENRVLNVTSEMMRLASRYKDLEARFATIAGVVNNQSVLITALEEQCLRSLGQGERAQAP PLVRAVPQNIPV-DNRFT------NEIQR--NSR----AFTRGSRKNSPTVSPFGIDPPP PQGTLTSDGPFKDCYEVRQAGHTTSGMYLLKTDNSDRLFQAWCEHGLDNGGWTVLQRRRG GAINFFRNWDTYKKGFGNIDGEHWLGLENIYNLSKQG--DYKLMIELEDWAGKKVYAEYS SFHLESENQGYRLRLGTYQGNAGDSLSSNNGKQFTTLDRDRDAFSGNCAHFHRGGWWYND CGQTNLNGVFHSGGVYRSKFQDGIFWADYGGGFYSLKSVLLMIRPID---- >XP_005501145.1 angiopoietin-related protein 1 [Columba livia] -------------MKIFKWTWGVL--LFL-LLSIGRCT-E-------------------- -----QSTPNK---------------------------------TSQRRHPRSAD--GGE EGKKCGYTFLVPEQKITG-PICVN------TNGPATGNRKDE----VTRMDIENLKDVLS KQKREIDILQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQ LENKVLNVTTEMLKMATKYKELEVKYAALTDLVNNQSVTISLLEEQCLRIFSRQDTHGSP PLVQVVPQHIPN-SQPYSPVLLGGNEIQRDPAYPRDRDVRPPPDPATSPTKSPFRV---- PPLALINEGPFKDCQQAKEAGHSNSGIYMIKPENSNEPMQLWCENSLDPGGWAVIQKRTD GSVNFFRNWDSYKKGFGNIDGEYWLGLENIYMLTNQD--NYRLLIELEDWSNKKVYAEYS SFRLEPESEFYRLRLGTYQGNAGDSMIWHNGKQFTTLDRDRDMYSGNCAHFHKGGWWYNA CAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLKAVQMMIRPID---- >XP_005690975.1 PREDICTED: angiopoietin-related protein 1 [Capra hircus] MQK--ESIQPHFKMKAFIWTLSVL--FFL-LMGIGHCRGG-------------------- -----QFKIKK---------------------------------ITQRRYPRATD--GKE EAKKCSYTFLVPEQKITG-PICVN------TKGQDAGTIKDM----ITRMDLENLKDVLS KQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQ LENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDPHVSP PLVQVVPQHIPH-SHQYTPGLLGGNEIQRDPSYP--RDLMPPPDLLTSPTKSPLKI---- PPVTFINEGPYKDCQHAKDAGHSVSGIYLIKPENSNGPMQLWCENSLDPGGWTVIQKRTD GSVNFFRNWENYKKGFGNIDGEYWLGLENIYLLSNQD--NYKLLIELEDWSDKKVYAEYS SFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNA CAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLRAVQMLIKPID---- >XP_006033079.1 angiopoietin-related protein 1 [Alligator sinensis] -------------MKIFTWTLGMV--LFL-LLSTGHCR-E-------------------- -----QAALNK---------------------------------VSQKRHPRSTD--GGE EGKKCGYTFLVPEQKITG-PICVN------TNGPRSDNRKDE----VTRMDIENLKDVLS KQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQ LENKILNVTTEMLKMATRYRELEVKYAALTDLVNNQSVIISLLEEQCLRVFSRQDTHGSP PLVQVVPQHIPN-SQPYTPVLLGGNEIQRDPGYPRDRDVRPPPDPATSPTKSPFRI---- PPLALINEGPFKDCQQAKEAGYSNSGIYMIKPENSNEPMQLWCENSLDPGGWAVIQKRTD GSVNFFRNWDSYKKGFGNVDGEYWLGLENIYMLTNQD--NYRLLIELEDWSNKKVYAEYS SFRLEPESEFYRLRLGTYQGNAGDSMIWHNGKQFTTLDRDRDMYTGNCAHFHKGGWWYNA CAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLKAVQMMIRPID---- >XP_006267321.1 PREDICTED: angiopoietin-related protein 1 [Alligator mississippiensis] -------------MKIFTWTLGMV--LFL-LLSTGHCR-E-------------------- -----QAAL-K---------------------------------VSQKRHPRSTD--GGE EGKKCGYTFLVPEQKITG-PICVN------TNGPRSDNRKDE----VTRMDIENLKDVLS KQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQ LENKILNVTTEMLKMATRYRELEVKYAALTDLVNNQSVIISLLEEQCLRVFSRQDTHGSP PLVQVVPQHIPN-SQPYTPVLLGGNEIQRDPGYPRDRDVRPPPDPATFPTKSPFRI---- PPLALINEGPFKDCQQAKEAGYSNSGIYMIKPENSNEPMQLWCENSLDPGGWAVIQKRTD GSFNFFRNWDSYKKGFGNVDGEYWLGLENIYMLTNQD--NYRLLIELEDWSNKKVYAEYS SFRLEPESEFYRLRLGTYQGNAGDSMIWHNGKQFTTLDRDRDMYTGNCAHFHKGGWWYNA CAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLKAVQMMIRPID---- >XP_015827157.1 PREDICTED: angiopoietin-related protein 1-like [Nothobranchius furzeri] -------------MQGLIWSLCAL--LCLSLWEESHCRSS-------------------- ------RNIRS---------------------------------VNEPSLLRTKRALQDT DAKKCSYTFLVPEQRITG-PICAS------TTGPEPD--KDR----VTRMDISDVREVLN KQRREIETLQLVVEVDGNLVNEMKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELVQ LENRVLNVTSEMMRLASRYKELEARFATMAGVVNNQSILISALEEQCLRTLGRSELPPVP PLVQVVPENIPI-DNRFT------NEIVT--KNQ----AFSRASRRESPTRSPFGMDPPP PQGTLTSDGPFKDCYQVRQAGYTTSGMYLLKTDNSEQLIQAWCEHGLDNGGWTVLQRRRD GSVNFFRNWENYKKGFGNIDGEHWLGLQNIFNLAKQG--DYRLMIELEDWAGKKVYAEYS SFHLESESEGYKLRLGTYQGNAGDSFSSNNGKAFTTLDRDKDTFSGNCAHYHKGGWWYNA CGQTNLNGVWYSGGVYRSKFQDGIFWADYGGGFYSLKCVRLMIRPID---- >XP_020724522.1 angiopoietin-related protein 1 [Odocoileus virginianus texanus] MQK--DSIQPHFKMKAFIWTLSVL--FFL-LMGIGHCRGG-------------------- -----QFKIKK---------------------------------ITQRRYPRATD--GKE EAKKCSYTFLVPEQKITG-PICVN------TKGQDAGTIKDM----ITRMDLENLKDVLS KQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQ LENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDPHVSP PLVQVVPQHIPN-SHQYTPGLLGGNEIQRDPGYP--RDLMPPSDLITSPTKSPLKI---- PPVTFINEGPYKDCQHAKDAGHSVSGIYMIKPENSKGPMQLWCENSLDPGGWTVIQKRTD GSVNFFRNWENYKKGFGNIDGEYWLGLENIYLLSNQD--NYKLLIELEDWSEKKVYAEYS SFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNA CAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLRAVQMLIKPID---- >XP_030290205.1 angiopoietin-related protein 1 [Sparus aurata] -------------MQGLMWSLCAL--LCLSLWEESYCRSS-------------------- ------REARR---------------------------------TKVPSLHRSKRAPLDP NAKKCSYTFLVPEQRITG-PICAS------TTGPEPD--KDR----VTRMDIADVREVLS KQRREIETLQLVVDVDGNLVNEMKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELAQ LENRVLNVTSEMMRLASRYKELESRYATMAGVVNNQSILISALEEQCMRTLGRSELPVVP PLVQVVPQNIPV-NNRFT------NEIQRYNNNR----AFPRGSRMETPTASPFGIDPPP PQGTLTSDGPFKDCFQVRQAGHATSGMYLLKTDANDRLIQAWCEHGLDNGGWTVLQRRKD GSVNFFRNWENYKKGFGNIDGEHWLGLDNIYNLGKQG--DYKLMVELEDWTGKKVYAEYS SFHLESESEGYRLRLGTYQGNAGDSFSSHNGKQFTTLDRDKDAFSGNCAHFHKGGWWYNA CGQTNLNGVWYSGGVYRSKFQDGIFWADYGGGFYSLKSVRLMIRPID---- >XP_040216274.1 angiopoietin-related protein 1 isoform X1 [Rana temporaria] MKSCLDSSLDRIEMDTTLWTLKVL--LLS-LFTAGHCAKS-------------------- -----KLGSQS---------------------------------GTSIRLARSTDYAENN DGKKCGYTFLVPQQKITG-PICVS------TKGPGAN--KDQ----VTRMDLENVKDSLT KQRREMEMLQVLVDVDGNIVSEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLEIAQ LENRILNVTAEMLRAATRYKELEVKYASLVDLVNNQSAIITLLEEQCMSVFSRRDSQGSP PLVQVVPQHIPN-SKPYTPGLAGGNEIQRDTGYPRARDSRQPPQ-APVPTVSPFRV---- PPVTVINEGPFKDCKHARESGFTSSGIYLIKPTNANSPMQLWCENNLDPGGWAVIQRRID GSANFFRNWETYKKGFGNIDSEYWLGLENIYQLSNQD--NYKLLIELEDWNNKKVYAEYS SFRLEPETDFYRLRLGTYQGNAGDSMVWHNGKQFTTLDRDRDMYTGNCAHFHKGGWWYNA CAHANLNGVWYRGGVYRSKHQDGIYWAEYRGGSYSLKKVQMMIRPID---- >KAB0341181.1 hypothetical protein FD754_018107 [Muntiacus muntjak] MQF--NSIQPHFKMKAFIWTLSVL--FFL-LMGIGHCRGG-------------------- -----QFKIKK---------------------------------ITQRRYPRATD--GKE EAKKCSYTFLVPEQKITG-PICVN------TKGQDAGTIKDM----ITRMDLENLKDVLS KQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQ LENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDPHVSP PLVQVVPQHIPN-SHQYTPGLLGGNEIQRDPGYP--RDLMPPPDLVTSPTKSPLKI---- PPVTFINEGPYKDCQHAKDAGHSVSGIYMIKPENSKGPLQLWCENSLDPGGWTVIQKRTD GSVNFFRNWENYKKGFGNIDGEYWLGLENIYLLSNQD--NYKLLIELEDWSDKKVYAEYS SFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNA CAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLRAVQMLIKPID---- >XP_043341746.1 angiopoietin-related protein 1 isoform X1 [Cervus canadensis] MQK--DSIQPHFKMKAFIWTLSVL--FFL-LMGIGHCRGG-------------------- -----QFKIKK---------------------------------ITQRRYPRATD--GKE EAKKCSYTFLVPEQKITG-PICVN------TKGQDAGTIKDM----ITRMDLENLKDVLS KQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQ LENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDPHVSP PLVQVVPQHIPN-SHQYTPGLLGGNEIQRDPGYP--RGLMPPPDLVTSPTKSPLKI---- PPVTFINEGPYKDCQHAKDAGHSVSGIYMIKPENSKGPMQLWCENSLDPGGWTVIQKRTD GSVNFFRNWENYKKGFGNIDGEYWLGLENIYLLSNQD--NYKLLIELEDWSDKKVYAEYS SFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNA CAHSNLNGVWYRGGQYRSKYQDGIFWAEYRGGSYSLRAVQMLIKPID---- >XP_043779981.1 angiopoietin-related protein 1 isoform X1 [Cervus elaphus] MQK--DSIQPHFKMKAFIWTLSVL--FFL-LMGIGRCRGG-------------------- -----QFKIKK---------------------------------ITQRRYPRATD--GKE EAKKCSYTFLVPEQKITG-PICVN------TKGQDAGTIKDM----ITRMDLENLKDVLS KQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQ LENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDPHVSP PLVQVVPQHIPN-SHQYTPGLLGGNEIQRDPGYP--RGLMPPPDLVTSPTKSPLKI---- PPVTFINEGPYKDCQHAKDAGHSVSGIYMIKPENSKGPMQLWCENSLDPGGWTVIQKRTD GSVNFFRNWENYKKGFGNIDGEYWLGLENIYLLSNQD--NYKLLIELEDWSDKKVYAEYS SFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNA CAHSNLNGVWYRGGQYRSKYQDGIFWAEYRGGSYSLRAVQMLIKPID---- >XP_018113986.1 angiopoietin-related protein 1 [Xenopus laevis] -------------MDTTLWNLGLM--LFL-VVPTGLCSNS-------------------- -----DTKSRR---------------------------------QTLTRIARSTD--EVD DGKRCGYTFLVPQQKVTG-PICVL------TKGSGPN--KEL----VTRMDLENVKDVLA KQRRDMEMLQVVVAVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNALEVSQ LETKILNVTSEMLRAATRYKELELKYASLVDVVNNQSSVIALLEEQCMKVFSRRDSPGSP PLVQVVPQHYPQ-IHQYTPGLGGGNEIQRDTGYPRVRDSRQPPQ---APTSSPFRI---- PPVTIIDEGPFRDCQHAKESGFSSSGIYLIKPDNANSPMQLWCENSLDPGGWAVIQRRTD GSANFFRNWETYKKGFGNIDAEYWLGLENIYQLTNQD--NYRLLIELEDWSNKKVYAEYS SFRLEPESEFYKLRLGTYQGNAGDSMVWHNGKQFTTLDRDKDMYSGNCAHFHKGGWWYNA CAHANLNGVWYRGGHYRSKHQDGIYWAEYRGGSYSLKAVQMLIRPID---- >XP_003211422.1 angiopoietin-related protein 2 [Meleagris gallopavo] -------------MMTTKF-ICLM--LIA-AVGTAASKTQ-------------------- -----EFEDNDEE--REQE------------------------FIYMNRYKRSSD----- PQDKCTYTFIVPQQRVTG-AICVN------SKEPEV-LLENR----VNKQELQLLNNELL KQKRQIETLQQLVEVDGGIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNALELSQ LENKILNQTADMLQLANKYKDLEYKYQHLMSIANNQSVIINQLEEYCQRMPSIKPLPQTP QPPSKVYQ--PP-TYNRMINQISTNEIQSDQNLK-----VLPPTLPTMPAVT--SI---- PTSTDKPSGPWRDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLD GSVNFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQG--NYKLLITMEDWSGRKVFAEYA SFRLEPESEYYKLRLGRYNGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNA CAHSNLNGVWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRPNPNTFH >XP_039268423.1 angiopoietin-related protein 2-like [Styela clava] -------------MSR----IVVVT-LFIALLFCGHVRSQLTVVDPPIMQIATGGDNNGK SNMKYDVKIRKYTVVRVPETPPSTTTEISTTTTTPPPDLDVNHIEVQTRSTFEEN--LLE EDHDCAFTFTLPNPRPSNQQVCVRDVRALMTSYPEERRSGDEEALNTLRNEISLWQESMG DLKTQIEE-RLAVPSLEPVRNDVRLLQKESRNMNFRISQLYMQLLHEIIRKRDDTIEYTS VENSVMNVTIKYYELKEKHEALVTDHKALKQQSQSQQEQIKILQTKMEEMVHRMNRMAVD --IQLM-------------GIDDEKDEVNDTA---------------------------- NSSLSESRSSYTNCVDIQLYASKESGIYILTLPSLSRKMKVWCDFEQDPGGWTVIQRRSE GKVNFYRNFASYQRGFGSLEGEFWLGLENIHHLTNQPGVNYKLHIDMEDWSGRKTFVEYG SFKLEGQDEGYRLKVAHYSGTAGDSLTWHNNMKFTTKNVDNDPFARNCANYQKGGWWYNT CAHSNLNGVYYMGGHYRSKFQDGIYWSEWRGGSYSLKHVEMKIKPSE----
BMGE Cleaned alignment of selected proteins >sp|O95841|ANGL1_HUMAN Angiopoietin-related protein 1 OS=Homo sapiens OX=9606 GN=ANGPTL1 PE=2 SV=1 MKTFTWTLGVLLVDTGHCRGGQFKIKKINQRRYPRATDGKEEAKKCAYTFLVPEQRITGPICVNTKGQDASTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDTHVSPPLVQVVPQHIPNSQQYTPGLLGGNEIQRDPGYPRDLMPPPDLATSPTKSPFKIPPVTFINEGPFKDCQQAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPID >tr|Q5KQU0|Q5KQU0_DANRE Angiopoietin-like 1 OS=Danio rerio OX=7955 GN=angptl1a PE=2 SV=1 MRGVTWCMGTMLLGKSH---------SGTELLHSRQRRAD-DSKKCSYTFLMPQQKITGPICASATGPEPD--KDRVTRMDISDVREILSKQRREIEMLQLVADVDGNLVNEMKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELAQLENRVLNVTTEMLRLASRYKELEMRFAGLAGTVNNQSVLIAALEERCLRGYGRQDLPAVPPLVQVVPESIPANNRFT------NEIQRDNNNR--AFPRGSRMDTPTPDPLGIPQGTLTADGPFKDCSQVRQAGHSTSGMYLLKAEGSDRLIQAWCEHKLDNGGWTVFQRRKDGSVNFFRNWENYKKGFGNIDGEHWLGLENIYNLAKQGDYKLLVELEDWVGKKVYAEYSSFHLEPESEGFRLRLGTYQGNAGDSLTSHNGKPFTTLDRDKDAFTGNCAHFHKGGWWYNACGQTNLNGVWYSGGVYRSKFQDGIFWAEYGGGYYSLKSVRMMIRPID >NP_082609.2 angiopoietin-related protein 1 precursor [Mus musculus] MKAFVWTLSVLL-GSGHCKGGQLKIKKITQRRYPRATDGKEEAKKCSYTFLVPEQKITGPICVNTKGQDAGTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVTITVLEEQCLRMFSRQDPHASPPLVQVVPRHSPNSHQYTPGLLGGNEIQRDPGYPRDVMPPPDLPTAPTKSPFKIPAVTFINEGPFKDCQQAKEAGHSASGIYMIKPENSNGLMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLDNIYKLSNQDNYKLMIELEDWSEKKVYAEYSSFRLEPESDYYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDTYTGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPID >XP_024831936.1 angiopoietin-related protein 1 isoform X1 [Bos taurus] MKAFIWTLSVLLMGIGHGRGRQFKIKKITQRRYPRATDGKEDAKKCSYTFLVPEQKITGPICVNTKGQDAGTIKDMITRMDLENLKDVLSKQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDPHVSPPLVQVVPQHIPNSHQYTPGLLGGNEIQRDPGYPRDLMPPPDLVTSPTKSPLKIPPVTFINEGPYKDCQHAKDAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYLLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLRAVQMLIKPID >XP_038526496.1 angiopoietin-related protein 1 isoform X1 [Canis lupus familiaris] MKAFIWTLSALLMGIGHCRGGQFKMKKITQRRYPRATDAKEEAKKCAYTFLVPEQKITGPICVNTKGQDASMIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNITTEMLKMATRYKELEVKYASLTDLVNNQSVMITLLEEQCLKIFSRQDPHVSPPLVQVVPQHIPNSHQYTPGLLGGNEIQRDPGYPRDLMPPPDLGTSPTKSPFKIPPVTFINEGPFKDCQHAKEAGHSVSGIYMIKPENSNGPIQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFFRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLRAVQMMIKPID >NP_001102853.1 angiopoietin-related protein 1 precursor [Rattus norvegicus] MKTFVWILSVVL-GIGHCKGGQFKIKKTTQRRYPRATDGKEETKKCSYTFLVPEQKITGPICVNTKGQDAGTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITVLEEQCLRLFSRQDPHVSPPLVQVVPRHIPNSHQDTPGLLAGNEIQRDPGYPRDLMPPPDLATAPTKSPFKIPAVTFINEGELPFPGQWK---------------NEAAMLYNPCDNTL----------RTS--------------------------------------------------------------------------------------------------------------------------------------------------------------------- >XP_001155579.1 angiopoietin-related protein 1 [Pan troglodytes] MKAFTWTLGVLLVDAGHCRGGQFKIKKINQRRYPRATDGKEEAKKCAYTFLVPEQRITGPICVNTKGQDASTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDTHVSPPLVQVVPQHIPNSHQYTPGLLGGNEIQRDPGYPRDLMPPPDLATSPTKSPFKIPPVTFINEGPFKDCQQAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPID >NP_001264594.1 angiopoietin-related protein 1 precursor [Gallus gallus] MKILKWTLGMLLLSIGRCT-EPSTLNKTSQRRHPRSTDGGEEGRKCGYTFLVPEQKITGPICVN-NEPGTGNRKDEVTRMDIENLKDVLSKQKREIDILQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKVLNVTTEMLKMATKYKELEVKYAALTDLVNNQSVIISLLEEQCLRIFSRQDTHGSPPLVQVVPQHIPNSQPYTPVLLGGNEIQRDPGYPRDVRPPPDPATSPTKSPFRVPPLALINEGPFKDCQHAKDAGYSNSGIYMIKAENSNEPMQLWCENSLDPGGWAVIQKRTDGSVNFFRNWDSYKKGFGNIDGEYWLGLENIYMLTNQDNYRLLIELEDWSNKKVYAEYSSFRLEPENEFYRLRLGTYQGNAGDSMIWHNGKQFTTLDRDRDMYSGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLKAVQMMIRPID >XP_005667844.1 angiopoietin-related protein 1 isoform X1 [Sus scrofa] MKALIWTLSVLLMGIGQCRGGQFKIKKITQRRYPRATDGKEEVKKCAYTFLVPEQKITGPICVNTKGQDAGTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDPHLSPPLVQVVPQHIPNSHQYTPGLLGGNEIQRDPGYPRDLMPPPDLATPPTKSPFKIPPVTFINEGPFKDCQHAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNTDGEYWLGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSRYQDGIFWAEYRGGSYSLRAVQMMIKPID >XP_002715049.1 PREDICTED: angiopoietin-related protein 1 [Oryctolagus cuniculus] MKAFIWTAGVLLIGTGHCRGGQFKIKKMTQRRYPRATDGKEEVKKCSYTFLVPEQKITGPICVNTKGQDAGAMKDMVTRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKVLNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITVLEEQCLRIFSRQDTHVSPPLVQVVPQHIPNSHQYTPGLLGGNEIQRDPGYPRDLMPPPDLATSPTKSPFKMPPVTFINEGPFKDCQQAKEAGHSISGIYLIKPENSNGPMQLWCENSLDPGGWTVIQKRKDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEYYRLRLGTYQGNAGDSLMWHNGKQFTTLDRDKDVYTGNCAHFHKGGWWYNTCAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPID >XP_002809805.1 angiopoietin-related protein 1 [Pongo abelii] MKAFTWTLGVLLVDAGHCRGGQFKIKKINQRRYPRATDGKEEAKKCAYTFLVPEQRITGPICVNTKGQDASTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLRMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDTHVSPPLVQVVPQHIPNSHQYTPGLLGGNEIQRDPGYPRDLMPPADLATSPTKSPFKIPPVTFINEGPFKDCQQAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPID >XP_003824749.1 angiopoietin-related protein 1 [Pan paniscus] MKAFTWTLGVLLVDAGHCRGGQFKIKKINQRRYPRATDGKEEAKKCAYTFLVPEQRITGPICVNTKGQDASTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDTHVSPPLVQVVPQHIPNSHQYTPGLLGGNEIQRDPGYPRDLMPPPDLATSPTKSPFKIPPVTFINEGPFKDCQQAKEAGHSVSGIYMIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPID >XP_003999280.1 angiopoietin-related protein 1 [Felis catus] MKAFIWTLSVLLMGIGHCRGGQFKIKKITQRRYPRATDGKEEAKKCSYTFLVPEQKITGPICVNTKGQDASTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLKIFSRQDPHVSPPLVQVVPQHIPNSHPYTPGLLGGNEIQRDPGYPRDLMPLPDLGTSSTKSPLKIPPVTFINEGPFKDCQHAKEAGHSVSGIYMIKPENSNGPIQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFFRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLRAVQMMIKPID >XP_004013880.1 angiopoietin-related protein 1 [Ovis aries] MKAFIWTLSVLLMGIGHCRGGQFKIKKITQRRYPRATDGKEEAKKCSYTFLVPEQKITGPICVNTKGQDAGTIKDMITRMDLENLKDVLSKQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDPHVSPPLVQVVPQHTPHSHQYTPGLLGGNEIQRDPGYPRDLMPPPDLSTSPTKSPLKIPPVTFINEGPYKDCQHAKDAGHSVSGIYLIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYLLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLRAVQMLIKPID >XP_004028013.1 angiopoietin-related protein 1 [Gorilla gorilla gorilla] MKAFTWTLGVLLVDAGHCRGGQFKIKKINQRRYPRATDGKEEAKKCAYTFLVPEQRITGPICVNTKGQDASTIKDMITRMDLENLKDVLSRQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDTHVSPPLVQVVPQHIPNSHQYTPGLLGGNEIQRDPGYPRDLMPPPDLATSPTKSPFKIPPVTFINEGPFKDCQQAKEAGHSVSGIYMIKPQNSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNTDGEYWLGLENIYMLSNQDNYKLLIELEDWSDKKVYAQYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKHQDGIFWAEYRGGSYSLRAVQMMIKPID >XP_004068226.1 angiopoietin-related protein 1 [Oryzias latipes] MQGLVWSLCVLLWEESSCRSS-RETQRTKEPFLKRSKRTDPNAKQCSYTFLVPEQRITGPICASTTGPEPD--KDRVTRMDIADVREVLNKQRREIETLQLVVDVDGNLVNEMKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELAQLENRVLNVTSEMMRLASRYKDLEARFATIAGVVNNQSVLITALEEQCLRSLGQGERAQAPPLVRAVPQNIPVDNRFT------NEIQR--NSR--AFTRGSRKNSPTVSPFGIPQGTLTSDGPFKDCYEVRQAGHTTSGMYLLKTDNSDRLFQAWCEHGLDNGGWTVLQRRRGGAINFFRNWDTYKKGFGNIDGEHWLGLENIYNLSKQGDYKLMIELEDWAGKKVYAEYSSFHLESENQGYRLRLGTYQGNAGDSLSSNNGKQFTTLDRDRDAFSGNCAHFHRGGWWYNDCGQTNLNGVFHSGGVYRSKFQDGIFWADYGGGFYSLKSVLLMIRPID >XP_005501145.1 angiopoietin-related protein 1 [Columba livia] MKIFKWTWGVLLLSIGRCT-EQSTPNKTSQRRHPRSADGGEEGKKCGYTFLVPEQKITGPICVNTNGPATGNRKDEVTRMDIENLKDVLSKQKREIDILQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKVLNVTTEMLKMATKYKELEVKYAALTDLVNNQSVTISLLEEQCLRIFSRQDTHGSPPLVQVVPQHIPNSQPYSPVLLGGNEIQRDPAYPRDVRPPPDPATSPTKSPFRVPPLALINEGPFKDCQQAKEAGHSNSGIYMIKPENSNEPMQLWCENSLDPGGWAVIQKRTDGSVNFFRNWDSYKKGFGNIDGEYWLGLENIYMLTNQDNYRLLIELEDWSNKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMIWHNGKQFTTLDRDRDMYSGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLKAVQMMIRPID >XP_005690975.1 PREDICTED: angiopoietin-related protein 1 [Capra hircus] MKAFIWTLSVLLMGIGHCRGGQFKIKKITQRRYPRATDGKEEAKKCSYTFLVPEQKITGPICVNTKGQDAGTIKDMITRMDLENLKDVLSKQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDPHVSPPLVQVVPQHIPHSHQYTPGLLGGNEIQRDPSYPRDLMPPPDLLTSPTKSPLKIPPVTFINEGPYKDCQHAKDAGHSVSGIYLIKPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYLLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLRAVQMLIKPID >XP_006033079.1 angiopoietin-related protein 1 [Alligator sinensis] MKIFTWTLGMVLLSTGHCR-EQAALNKVSQKRHPRSTDGGEEGKKCGYTFLVPEQKITGPICVNTNGPRSDNRKDEVTRMDIENLKDVLSKQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYAALTDLVNNQSVIISLLEEQCLRVFSRQDTHGSPPLVQVVPQHIPNSQPYTPVLLGGNEIQRDPGYPRDVRPPPDPATSPTKSPFRIPPLALINEGPFKDCQQAKEAGYSNSGIYMIKPENSNEPMQLWCENSLDPGGWAVIQKRTDGSVNFFRNWDSYKKGFGNVDGEYWLGLENIYMLTNQDNYRLLIELEDWSNKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMIWHNGKQFTTLDRDRDMYTGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLKAVQMMIRPID >XP_006267321.1 PREDICTED: angiopoietin-related protein 1 [Alligator mississippiensis] MKIFTWTLGMVLLSTGHCR-EQAAL-KVSQKRHPRSTDGGEEGKKCGYTFLVPEQKITGPICVNTNGPRSDNRKDEVTRMDIENLKDVLSKQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYAALTDLVNNQSVIISLLEEQCLRVFSRQDTHGSPPLVQVVPQHIPNSQPYTPVLLGGNEIQRDPGYPRDVRPPPDPATFPTKSPFRIPPLALINEGPFKDCQQAKEAGYSNSGIYMIKPENSNEPMQLWCENSLDPGGWAVIQKRTDGSFNFFRNWDSYKKGFGNVDGEYWLGLENIYMLTNQDNYRLLIELEDWSNKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMIWHNGKQFTTLDRDRDMYTGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLKAVQMMIRPID >XP_015827157.1 PREDICTED: angiopoietin-related protein 1-like [Nothobranchius furzeri] MQGLIWSLCALLWEESHCRSS-RNIRSVNEPSLLRTKRQDTDAKKCSYTFLVPEQRITGPICASTTGPEPD--KDRVTRMDISDVREVLNKQRREIETLQLVVEVDGNLVNEMKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELVQLENRVLNVTSEMMRLASRYKELEARFATMAGVVNNQSILISALEEQCLRTLGRSELPPVPPLVQVVPENIPIDNRFT------NEIVT--KNQ--AFSRASRRESPTRSPFGMPQGTLTSDGPFKDCYQVRQAGYTTSGMYLLKTDNSEQLIQAWCEHGLDNGGWTVLQRRRDGSVNFFRNWENYKKGFGNIDGEHWLGLQNIFNLAKQGDYRLMIELEDWAGKKVYAEYSSFHLESESEGYKLRLGTYQGNAGDSFSSNNGKAFTTLDRDKDTFSGNCAHYHKGGWWYNACGQTNLNGVWYSGGVYRSKFQDGIFWADYGGGFYSLKCVRLMIRPID >XP_020724522.1 angiopoietin-related protein 1 [Odocoileus virginianus texanus] MKAFIWTLSVLLMGIGHCRGGQFKIKKITQRRYPRATDGKEEAKKCSYTFLVPEQKITGPICVNTKGQDAGTIKDMITRMDLENLKDVLSKQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDPHVSPPLVQVVPQHIPNSHQYTPGLLGGNEIQRDPGYPRDLMPPSDLITSPTKSPLKIPPVTFINEGPYKDCQHAKDAGHSVSGIYMIKPENSKGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYLLSNQDNYKLLIELEDWSEKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLRAVQMLIKPID >XP_030290205.1 angiopoietin-related protein 1 [Sparus aurata] MQGLMWSLCALLWEESYCRSS-REARRTKVPSLHRSKRLDPNAKKCSYTFLVPEQRITGPICASTTGPEPD--KDRVTRMDIADVREVLSKQRREIETLQLVVDVDGNLVNEMKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELAQLENRVLNVTSEMMRLASRYKELESRYATMAGVVNNQSILISALEEQCMRTLGRSELPVVPPLVQVVPQNIPVNNRFT------NEIQRYNNNR--AFPRGSRMETPTASPFGIPQGTLTSDGPFKDCFQVRQAGHATSGMYLLKTDANDRLIQAWCEHGLDNGGWTVLQRRKDGSVNFFRNWENYKKGFGNIDGEHWLGLDNIYNLGKQGDYKLMVELEDWTGKKVYAEYSSFHLESESEGYRLRLGTYQGNAGDSFSSHNGKQFTTLDRDKDAFSGNCAHFHKGGWWYNACGQTNLNGVWYSGGVYRSKFQDGIFWADYGGGFYSLKSVRLMIRPID >XP_040216274.1 angiopoietin-related protein 1 isoform X1 [Rana temporaria] MDTTLWTLKVLLFTAGHCAKSKLGSQSGTSIRLARSTDENNDGKKCGYTFLVPQQKITGPICVSTKGPGAN--KDQVTRMDLENVKDSLTKQRREMEMLQVLVDVDGNIVSEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLEIAQLENRILNVTAEMLRAATRYKELEVKYASLVDLVNNQSAIITLLEEQCMSVFSRRDSQGSPPLVQVVPQHIPNSKPYTPGLAGGNEIQRDTGYPRDSRQPPQ-APVPTVSPFRVPPVTVINEGPFKDCKHARESGFTSSGIYLIKPTNANSPMQLWCENNLDPGGWAVIQRRIDGSANFFRNWETYKKGFGNIDSEYWLGLENIYQLSNQDNYKLLIELEDWNNKKVYAEYSSFRLEPETDFYRLRLGTYQGNAGDSMVWHNGKQFTTLDRDRDMYTGNCAHFHKGGWWYNACAHANLNGVWYRGGVYRSKHQDGIYWAEYRGGSYSLKKVQMMIRPID >KAB0341181.1 hypothetical protein FD754_018107 [Muntiacus muntjak] MKAFIWTLSVLLMGIGHCRGGQFKIKKITQRRYPRATDGKEEAKKCSYTFLVPEQKITGPICVNTKGQDAGTIKDMITRMDLENLKDVLSKQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDPHVSPPLVQVVPQHIPNSHQYTPGLLGGNEIQRDPGYPRDLMPPPDLVTSPTKSPLKIPPVTFINEGPYKDCQHAKDAGHSVSGIYMIKPENSKGPLQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYLLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGHYRSKYQDGIFWAEYRGGSYSLRAVQMLIKPID >XP_043341746.1 angiopoietin-related protein 1 isoform X1 [Cervus canadensis] MKAFIWTLSVLLMGIGHCRGGQFKIKKITQRRYPRATDGKEEAKKCSYTFLVPEQKITGPICVNTKGQDAGTIKDMITRMDLENLKDVLSKQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDPHVSPPLVQVVPQHIPNSHQYTPGLLGGNEIQRDPGYPRGLMPPPDLVTSPTKSPLKIPPVTFINEGPYKDCQHAKDAGHSVSGIYMIKPENSKGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYLLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGQYRSKYQDGIFWAEYRGGSYSLRAVQMLIKPID >XP_043779981.1 angiopoietin-related protein 1 isoform X1 [Cervus elaphus] MKAFIWTLSVLLMGIGRCRGGQFKIKKITQRRYPRATDGKEEAKKCSYTFLVPEQKITGPICVNTKGQDAGTIKDMITRMDLENLKDVLSKQKREIDVLQLVVDVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNSLELSQLENKILNVTTEMLKMATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDPHVSPPLVQVVPQHIPNSHQYTPGLLGGNEIQRDPGYPRGLMPPPDLVTSPTKSPLKIPPVTFINEGPYKDCQHAKDAGHSVSGIYMIKPENSKGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYLLSNQDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLRLGTYQGNAGDSMMWHNGKQFTTLDRDKDMYAGNCAHFHKGGWWYNACAHSNLNGVWYRGGQYRSKYQDGIFWAEYRGGSYSLRAVQMLIKPID >XP_018113986.1 angiopoietin-related protein 1 [Xenopus laevis] MDTTLWNLGLMVVPTGLCSNSDTKSRRQTLTRIARSTDEVDDGKRCGYTFLVPQQKVTGPICVLTKGSGPN--KELVTRMDLENVKDVLAKQRRDMEMLQVVVAVDGNIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNALEVSQLETKILNVTSEMLRAATRYKELELKYASLVDVVNNQSSVIALLEEQCMKVFSRRDSPGSPPLVQVVPQHYPQIHQYTPGLGGGNEIQRDTGYPRDSRQPPQ---APTSSPFRIPPVTIIDEGPFRDCQHAKESGFSSSGIYLIKPDNANSPMQLWCENSLDPGGWAVIQRRTDGSANFFRNWETYKKGFGNIDAEYWLGLENIYQLTNQDNYRLLIELEDWSNKKVYAEYSSFRLEPESEFYKLRLGTYQGNAGDSMVWHNGKQFTTLDRDKDMYSGNCAHFHKGGWWYNACAHANLNGVWYRGGHYRSKHQDGIYWAEYRGGSYSLKAVQMLIRPID >XP_003211422.1 angiopoietin-related protein 2 [Meleagris gallopavo] MMTTKF-ICLMAVGTAASKTQEFEDNDIYMNRYKRSSD---PQDKCTYTFIVPQQRVTGAICVNSKEPEV-LLENRVNKQELQLLNNELLKQKRQIETLQQLVEVDGGIVNEVKLLRKESRNMNSRVTQLYMQLLHEIIRKRDNALELSQLENKILNQTADMLQLANKYKDLEYKYQHLMSIANNQSVIINQLEEYCQRMPSIKPLPQTPQPPSKVYQ--PPTYNRMINQISTNEIQSDQNLK---VLPPTLPTMPAVT--SIPTSTDKPSGPWRDCLQALEDGHDTSSIYLVKPENTNRLMQVWCDQRHDPGGWTVIQRRLDGSVNFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLITMEDWSGRKVFAEYASFRLEPESEYYKLRLGRYNGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAHYQKGGWWYNACAHSNLNGVWYRGGHYRSRYQDGVYWAEFRGGSYSLKKVVMMIRPNP >XP_039268423.1 angiopoietin-related protein 2-like [Styela clava] MSR----IVVVLLFCGHVRSQDVKIRKEVQTRSTFEENLLEEDHDCAFTFTLPNPRPSNQVCVRTSYPEERRSGDETLRNEISLWQESMGDLKTQIEE-RLAVPSLEPVRNDVRLLQKESRNMNFRISQLYMQLLHEIIRKRDDTIEYTSVENSVMNVTIKYYELKEKHEALVTDHKALKQQSQSQQEQIKILQTKMEEMVHRMNRMAVD--IQLM------------GIDDEKDEVNDTA----------------------NSSLSESRSSYTNCVDIQLYASKESGIYILTLPSLSRKMKVWCDFEQDPGGWTVIQRRSEGKVNFYRNFASYQRGFGSLEGEFWLGLENIHHLTNQPNYKLHIDMEDWSGRKTFVEYGSFKLEGQDEGYRLKVAHYSGTAGDSLTWHNNMKFTTKNVDNDPFARNCANYQKGGWWYNTCAHSNLNGVYYMGGHYRSKFQDGIYWSEWRGGSYSLKHVEMKIKPSE
PhyML tree of selected proteins (XP_039268423_1_angiopoietin_related_protein_2_like__Styela_clava_:1.96066307,XP_003211422_1_angiopoietin_related_protein_2__Meleagris_gallopavo_:0.48130688,((((XP_002715049_1_PREDICTED__angiopoietin_related_protein_1__Oryctolagus_cuniculus_:0.03473781,(((NP_082609_2_angiopoietin_related_protein_1_precursor__Mus_musculus_:0.02865412,NP_001102853_1_angiopoietin_related_protein_1_precursor__Rattus_norvegicus_:0.08901024):0.02610211,((XP_005667844_1_angiopoietin_related_protein_1_isoform_X1__Sus_scrofa_:0.01763704,(XP_003999280_1_angiopoietin_related_protein_1__Felis_catus_:0.00881495,XP_038526496_1_angiopoietin_related_protein_1_isoform_X1__Canis_lupus_familiaris_:0.01522686):0.01088389):0.00000001,(XP_024831936_1_angiopoietin_related_protein_1_isoform_X1__Bos_taurus_:0.00653774,((KAB0341181_1_hypothetical_protein_FD754_018107__Muntiacus_muntjak_:0.0021707,(XP_020724522_1_angiopoietin_related_protein_1__Odocoileus_virginianus_texanus_:0.00651003,(XP_043341746_1_angiopoietin_related_protein_1_isoform_X1__Cervus_canadensis_:0.00000001,XP_043779981_1_angiopoietin_related_protein_1_isoform_X1__Cervus_elaphus_:0.00217342):0.00434672):0.00000001):0.00217263,(XP_004013880_1_angiopoietin_related_protein_1__Ovis_aries_:0.00438232,XP_005690975_1_PREDICTED__angiopoietin_related_protein_1__Capra_hircus_:0.00271269):0.00614532):0.00000001):0.01529841):0.00764919):0.00608556,(sp_O95841_ANGL1_HUMAN_Angiopoietin_related_protein_1_OS_Homo_sapiens_OX_9606_GN_ANGPTL1_PE_2_SV_1:0.00433507,(XP_004028013_1_angiopoietin_related_protein_1__Gorilla_gorilla_gorilla_:0.00648254,((XP_001155579_1_angiopoietin_related_protein_1__Pan_troglodytes_:0.00000001,XP_003824749_1_angiopoietin_related_protein_1__Pan_paniscus_:0.00000001):0,XP_002809805_1_angiopoietin_related_protein_1__Pongo_abelii_:0.00430979):0):0.00215384):0.01543765):0.00450655):0.06910215,((XP_006033079_1_angiopoietin_related_protein_1__Alligator_sinensis_:0.00000001,XP_006267321_1_PREDICTED__angiopoietin_related_protein_1__Alligator_mississippiensis_:0.00445754):0.01514165,(NP_001264594_1_angiopoietin_related_protein_1_precursor__Gallus_gallus_:0.01921699,XP_005501145_1_angiopoietin_related_protein_1__Columba_livia_:0.01966233):0.03173633):0.08537169):0.06938663,(XP_018113986_1_angiopoietin_related_protein_1__Xenopus_laevis_:0.11977972,XP_040216274_1_angiopoietin_related_protein_1_isoform_X1__Rana_temporaria_:0.11249556):0.12730323):0.07704817,(tr_Q5KQU0_Q5KQU0_DANRE_Angiopoietin_like_1_OS_Danio_rerio_OX_7955_GN_angptl1a_PE_2_SV_1:0.11042185,(XP_030290205_1_angiopoietin_related_protein_1__Sparus_aurata_:0.0361854,(XP_004068226_1_angiopoietin_related_protein_1__Oryzias_latipes_:0.11071839,XP_015827157_1_PREDICTED__angiopoietin_related_protein_1_like__Nothobranchius_furzeri_:0.0918654):0.02253845):0.10474197):0.39605983):0.23623067);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)