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PBID | Uniprot | Name | Gene | Alternative | Organism | Uniprot Description |
PB0152 | P98160 | Basement membrane-specific heparan sulfate proteoglycan core protein | HSPG2 | HSPG, PLC, PRCAN, SJA, SJS, SJS1, heparan sulfate proteoglycan 2 | Homo_sapiens | The LG3 peptide has anti-angiogenic properties that require binding of calcium ions for full activity. |
Domains | Gene Ontology |
PF00008 (2_EGF) PF00052 (3_Laminin_B) PF00053 (9_Laminin_EGF) PF00054 (3_Laminin_G_1) PF00057 (4_Ldl_recept_a) PF07679 (9_I-set) PF13895 (Ig_2) |
GO:0001540 (enables) amyloid-beta binding
GO:0005509 (enables) calcium ion binding GO:0005515 (enables) protein binding GO:0008022 (enables) protein C-terminus binding GO:0030021 (enables) extracellular matrix structural constituent conferring compression resistance GO:0046872 (enables) metal ion binding GO:0050750 (enables) low-density lipoprotein particle receptor binding GO:0001525 (involved in) angiogenesis GO:0006629 (involved in) lipid metabolic process GO:0006898 (involved in) receptor-mediated endocytosis GO:0006954 (involved in) inflammatory response GO:0007420 (involved in) brain development GO:0009887 (involved in) animal organ morphogenesis GO:0009888 (involved in) tissue development GO:0016525 (involved in) negative regulation of angiogenesis GO:0030154 (involved in) cell differentiation GO:0072359 (involved in) circulatory system development GO:0005604 (is active in) basement membrane GO:0005576 (located in) extracellular region GO:0005615 (located in) extracellular space GO:0005796 (located in) Golgi lumen GO:0005886 (located in) plasma membrane GO:0005925 (located in) focal adhesion GO:0043202 (located in) lysosomal lumen GO:0062023 (located in) collagen-containing extracellular matrix GO:0070062 (located in) extracellular exosome GO:0098797 (part of) plasma membrane protein complex |
External Links | Description |
Intact | Open source database system and analysis tools for molecular interaction data. |
Protein Atlas | An open access resource for human proteins |
InterPro (new pfam) | InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites. |