PB0150

DATABASE

Click here to access PB0150 phyletic profile

PBID	Uniprot	Name	Gene	Alternative	Organism	Uniprot Description
PB0150	Q9HCB6	Spondin-1	SPON1	VSGP/F-spondin, f-spondin	Homo_sapiens	Major factor for vascular smooth muscle cell.

Domains

Gene Ontology

PF00090 (5_TSP_1) PF02014 (Reeler) PF06468 (Spond_N) PF19028 (TSP1_spondin)

GO:0062023 (colocalizes with) collagen-containing extracellular matrix GO:0005201 (enables) extracellular matrix structural constituent GO:0005515 (enables) protein binding GO:0046872 (enables) metal ion binding GO:0050693 (enables) LBD domain binding GO:0007155 (involved in) cell adhesion GO:0010954 (involved in) positive regulation of protein processing GO:0032092 (involved in) positive regulation of protein binding GO:1902430 (involved in) negative regulation of amyloid-beta formation GO:1902993 (involved in) positive regulation of amyloid precursor protein catabolic process GO:0031012 (is active in) extracellular matrix GO:0005576 (located in) extracellular region GO:0005615 (located in) extracellular space GO:0005788 (located in) endoplasmic reticulum lumen

External Links	Description
Intact	Open source database system and analysis tools for molecular interaction data.
Protein Atlas	An open access resource for human proteins
InterPro (new pfam)	InterPro provides functional analysis of proteins by classifying them into families and predicting domains and important sites.

Seed proteins (Human and Zebrafish) >sp|Q9HCB6|SPON1_HUMAN Spondin-1 OS=Homo sapiens OX=9606 GN=SPON1 PE=1 SV=2 MRLSPAPLKLSRTPALLALALPLAAALAFSDETLDKVPKSEGYCSRILRAQGTRREGYTE FSLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALRENREGDKEEDHAGTFQIIDEE ETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKK LCEQDSTFDGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHS KNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAA PSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSG VTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPD NVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPC PDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTL PTEETEKCTVNEECSPSSCLMTEWGEWDECSATCGMGMKKRHRMIKMNPADGSMCKAETS QAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEDLEQVEKC MLPECPIDCELTEWSQWSECNKSCGKGHVIRTRMIQMEPQFGGAPCPETVQRKKCRIRKC LRNPSIQKLRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQERYMT VKKRFKSSQFTSCKDKKEIRACNVHPC >tr|F1R2Z9|F1R2Z9_DANRE F-spondin OS=Danio rerio OX=7955 GN=spon1b PE=4 SV=3 MMDKDGLVVLLVFLNVFLIHSDAFKRDTAERHSRSEGGFCRILRTQARSARRDGQNEFRL KVEGEPETYQPGSTYRVSLYASSPSYFRGFTLIALKEGREGVSPDDYAGTFKLIDESDTQ FMTNCPPAVTESIPRRRTRIQVFWTAPPSGSGCVTLKASVVQRRIIFFQDEGSLTKRLCE KDPVAITEKPAQECCACGTAKYRVTFYGNWSEKLHPKDYPRRANHWSALIGASHTRSYVL WEYGGFASEGVKQVSEYGSPVKMEEEIRQKGDDVMTVIKTKAQWPAWQPLNIRAAPSAEF SVDRVRHLMSFLTMLGPSPDWNVGLSGEDLCTRDCGWVQKLVKDLVPWDAGTDSGVSYES PNKPSIPQERIRPLTSLDHPQSPFYDPSGGPMTPLGRVVVERIARKGEQCNTVPDTIDDI VADIAQEEKEEGDNTPETCIYSNWSPWSACSSSTCDKGRRMRQRMLKAQLDPNLPCLHTQ DFEPCMGPGCSEEEASTCMMSEWISWSPCSASCGMGMRSRERYVKQFPEDGSSCTLPTEE TEKCVVNDDCSPSSCVVTEWGEWEPCSVSCGLGMRRRERMMKMDASDGSPCRVQMAEAEK CMMPECNAVVCMLSPWSDWGECSVSCGVGMRTRQRMLKTPVKPGQCPDELEQVEKCMLPE CPTDCMLSEWSAWSECNKSCGKGHMIRSRMVKLEPQFGGLPCPETVQRKKCKIRKCSRGS RASEKRKRQEVSDRRRAKQSRESVAEESTVVCPIRPWSSWTECTKPCDGGTQERVMTIKK KGKSSQHNHCKNKKEIRACNVHPC
Selected proteins from model organisms >sp|Q9HCB6|SPON1_HUMAN Spondin-1 OS=Homo sapiens OX=9606 GN=SPON1 PE=1 SV=2 MRLSPAPLKLSRTPALLALALPLAAALAFSDETLDKVPKSEGYCSRILRAQGTRREGYTE FSLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALRENREGDKEEDHAGTFQIIDEE ETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKK LCEQDSTFDGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHS KNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAA PSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSG VTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPD NVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPC PDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTL PTEETEKCTVNEECSPSSCLMTEWGEWDECSATCGMGMKKRHRMIKMNPADGSMCKAETS QAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEDLEQVEKC MLPECPIDCELTEWSQWSECNKSCGKGHVIRTRMIQMEPQFGGAPCPETVQRKKCRIRKC LRNPSIQKLRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQERYMT VKKRFKSSQFTSCKDKKEIRACNVHPC >tr|F1R2Z9|F1R2Z9_DANRE F-spondin OS=Danio rerio OX=7955 GN=spon1b PE=4 SV=3 MMDKDGLVVLLVFLNVFLIHSDAFKRDTAERHSRSEGGFCRILRTQARSARRDGQNEFRL KVEGEPETYQPGSTYRVSLYASSPSYFRGFTLIALKEGREGVSPDDYAGTFKLIDESDTQ FMTNCPPAVTESIPRRRTRIQVFWTAPPSGSGCVTLKASVVQRRIIFFQDEGSLTKRLCE KDPVAITEKPAQECCACGTAKYRVTFYGNWSEKLHPKDYPRRANHWSALIGASHTRSYVL WEYGGFASEGVKQVSEYGSPVKMEEEIRQKGDDVMTVIKTKAQWPAWQPLNIRAAPSAEF SVDRVRHLMSFLTMLGPSPDWNVGLSGEDLCTRDCGWVQKLVKDLVPWDAGTDSGVSYES PNKPSIPQERIRPLTSLDHPQSPFYDPSGGPMTPLGRVVVERIARKGEQCNTVPDTIDDI VADIAQEEKEEGDNTPETCIYSNWSPWSACSSSTCDKGRRMRQRMLKAQLDPNLPCLHTQ DFEPCMGPGCSEEEASTCMMSEWISWSPCSASCGMGMRSRERYVKQFPEDGSSCTLPTEE TEKCVVNDDCSPSSCVVTEWGEWEPCSVSCGLGMRRRERMMKMDASDGSPCRVQMAEAEK CMMPECNAVVCMLSPWSDWGECSVSCGVGMRTRQRMLKTPVKPGQCPDELEQVEKCMLPE CPTDCMLSEWSAWSECNKSCGKGHMIRSRMVKLEPQFGGLPCPETVQRKKCKIRKCSRGS RASEKRKRQEVSDRRRAKQSRESVAEESTVVCPIRPWSSWTECTKPCDGGTQERVMTIKK KGKSSQHNHCKNKKEIRACNVHPC >NP_742064.2 spondin-1 precursor [Rattus norvegicus] MRLSPAPLRLSRGPALLALALPLAAALAFSDETLDKVAKSEGYCSRILRAQGTRREGYTEFSLRVEGDPD FYKPGSSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRR TRIQVFWIAPPTGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDPTLDGVTDRPILDCCACGTAKYRLT FYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVL TVIKAKAQWPAWQPVNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDL IPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPD NVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCEKGKRMRQRMLKAQLDLSVPCPDTQDFQPCM GPGCSDEDGSTCTMSEWITWSPCSVSCGMGMRSRERYVKQFPEDGSVCMLPTEETEKCTVNEECSPSSCL VTEWGEWDDCSATCGMGMKKRHRMVKMSPADGSMCKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTC GKGMRTRQRMLKSLAELGDCNEDLEQAEKCMLPECPIDCELSEWSQWSECNKSCGKGHMIRTRTIQMEPQ FGGAPCPETVQRKKCRARKCLRSPSIQKLRWREARESRRSEQLREESDGEQFPGCRMRPWTAWSECTKLC GGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC >NP_663559.1 spondin-1 precursor [Mus musculus] MRLSPVSLRLSRGPALLALALPLAAALAFSDETLDKVTKSEGYCSRILRAQGTRREGYTEFSLRVEGDPD FYKPGSSYRVTLSAAPPSYFRGFTLIALKENQEGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRR TRIQVFWIAPPTGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDPTLDGVTDRPILDCCACGTAKYRLT FYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVL TVIKAKAQWPAWQPVNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDL IPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPD NVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCEKGKRMRQRMLKAQLDLSVPCPDTQDFQPCM GPGCSDEDGSTCTMSEWITWSPCSVSCGMGMRSRERYVKQFPEDGSVCMLPTEETEKCTVNEECSPSSCL VTEWGEWDDCSATCGMGMKKRHRMVKMSPADGSMCKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTC GKGMRTRQRMLKSLAELGDCNEDLEQAEKCMLPECPIDCELSEWSQWSECNKSCGKGHMIRTRTIQMEPQ FGGVPCPETVQRKKCRTRKCLRSPSVQKLRWREARESRRSEQLREESDGEQFPGCRMRPWTAWSECTKLC GGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC >NP_777168.1 spondin-1 precursor [Bos taurus] MRLSPVLLRLSRGPALLALALPLAVALAFSDETLDKVPKSEGYCSRILRVQGTRREGYTEFSLRVEGDPD FYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRR TRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTFDGVTDKPILDCCACGTAKYRLT FYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVL TVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDL IPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPD NVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCM GPGCSDEDGSTCTMSEWITWSPCSISCGTGTRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCL TTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMCKAETSQAEKCMMPECHTIPCLLSLWSEWSDCSVTC GKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPECPIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQ FGGTPCPETVQRKKCRIRKCLRNPSIQNLRWREARESRRSEQLREESDGDQFPGCRMRPWTAWSECTKLC GGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC >NP_990182.1 spondin-1 precursor [Gallus gallus] MAARLRPLALRLLARTFPLVARGFSDETLEKAAKSEGYCSRILRAQGTRREGYNEFSLRVEGDPEFYKPG NSYRVTLSAATPAYFRGFTLIALKEGKEGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQV FWTAPPTGTGCVILKASIVQKRIIYFQDEGSLTKRICEQDSASEGVTDKPTLDCCACGTAKYRLTFYGNW SEKTHPKDFPRRTNHWSAIIGSSHSKNYILWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKA KAQWPAWQPLNVRAAPSAEFSVDRHRHLMSFLTMLGPSPDWNVGLSAEDLCTKDCGWVQKVVQDLIPWDA GTDSGVTYESPNKPTVPQEKIRPLTSLDHPQSPFYDPEGGSIKLVARVVLERIARKGEQCNFVPDNIDDI VADLAPEEKEEDDTPETCIYSNWSPWSACSSSTCEKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCS DEDGSTCMMSDWITWSPCSVSCGMGTRSRERYVKQFPEDGSMCKVPTEETEKCIVNEECSPSSCLVTEWG EWDECSASCGTGMKRRHRMIKMTPADGSMCKAETTEAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMR TRQRMLKSAAELGDCNEELEQAEKCMLPECPIDCELTEWSQWSECNTSCGKGHMIRTRMIKIEPQFGGTA CPETVQRTKCRVRKCLRGPGMEKRRWKEAREKRRSEQAKKNIDNEQYPVCRLKPWTAWTECSTLCGGGIQ ERYMMVKKRSKSTQFTSCKDKKELRACNVHPC >XP_508295.3 spondin-1 [Pan troglodytes] MPRFLRQTLGIQRRKINTAAPLIASSEETKQRCAGGSGQNQPSLLPLLRRGPPLLALLSFAWLSSAQLSA APRPPSRGGHGLRVADASSELPLSAAPPPGRAFVGTTSGRSRVANAGGRGTKLGAAKMRLSPAPLKLSRT PALLALALPLAAALAFSDETLDKVPKSEGYCSRILRAQGTRREGYTEFSLRVEGDPDFYKPGTSYRVTLS AAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAG TGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTFDGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKD YPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQ PLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTY ESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEE KDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCT MSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLMTEWGEWDECSAT CGMGMKKRHRMIKMSPADGSMCKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKS LAELGDCNEDLEQVEKCMLPECPIDCELTEWSQWSECNKSCGKGHVIRTRMIQMEPQFGGAPCPETVQRK KCRIRKCLRNPSIQKLRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKK RFKSSQFTSCKDKKEIRACNVHPC >XP_534067.2 spondin-1 [Canis lupus familiaris] MRLSPAPPGLSPSPALLALALPLAAALAFSDETLDKVPKSEGYCSRILRAQGTRREGYTEFSLRVEGDPD FYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRR TRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSMFDGVTDKPILDCCACGTAKYRLT FYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVL TVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDL IPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPD NVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCM GPGCSDEDGSTCTMSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCL MTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMCKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTC GKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPECPIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQ FGGAPCPETVQRKKCRIRKCLKNPSIQKLRWREARESRRGEQLREESDGEQFPGCRMRPWTAWSECTKLC GGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC >XP_002708869.1 PREDICTED: spondin-1 [Oryctolagus cuniculus] MRLSPAPLRLSRTLALLALALPLAAALAFSDETLDKVAKSEGYCSRILRAQGTRREGYTEFSLRVEGDPD FYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRR TRIQVFWIAPPTGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTFDGVTDKPILDCCACGTAKYRLT FYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVL TVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDL IPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSIIQVARVVIERIARKGEQCNIVPD NVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCM GPGCSDEDGSTCTMSEWITWSPCSISCGTGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCL MTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMCKAETSQTEKCMMPECHTIPCLLSPWSEWSDCSVTC GKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPECPIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQ FGGAPCPETVQRKKCRVRKCLRNPSIQKLRWREARESRRGEQLREESDGEQFPGCRMRPWTAWSECTKLC GGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC >XP_002822053.2 spondin-1 [Pongo abelii] MRLSPATLKLSRTPALLALALPLAAALAFSDETLDKVPKSEGYCSRILRAQGTRREGYTEFSLRVEGDPD FYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRR TRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTFDGVTDKPILDCCACGTAKYRLT FYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVL TVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDL IPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPD NVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCM GPGCSDEDGSTCTMSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCL MTEWGEWDECSATCGMGMKKRHRMIKMSPADGSMCKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTC GKGMRTRQRMLKSLAELGDCNEDLEQVEKCMLPECPIDCELTEWSQWSECNKSCGKGHVIRTRMIQMEPQ FGGAPCPETVQRKKCRIRKCLRNPSIQKLRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLC GGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC >XP_003123014.4 spondin-1 [Sus scrofa] MRLSPASVKLSGSPALLALALPLAAALAFSDETLDKVPKSEGYCSRILRVQGTRREGYTEFSLRVEGDPD FYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRR TRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKVCEQDSTFDGVTDRPILDCCACGTAKYRLT FYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVL TVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDL IPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPD NVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCM GPGCSDEDGSTCTMSEWITWSPCSISCGTGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCL MTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMCKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTC GKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPECPIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQ FGGAPCPETVQRKKCRIRKCLRNPSIQKLRWREARESRRSEQLREESDGEQFPGCRMRPWTAWSECTKLC GGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC >XP_031409214.1 spondin-1 [Meleagris gallopavo] MCFTSSAKDAAFPHPIATDDVNTWCVVTLSAATPAYFRGFTLIALKEGKEGDKEEDHAGTFQIIDEEETQ FMSNCPVAVTESTPRRRTRIQVFWTAPPTGTGCVILKASIVQKRIIYFQDEGSLTKRICEQDSASEGVTD KPILDCCACGTAKYRLTFYGNWSEKTHPKDFPRRTNHWSAIIGSSHSKNYILWEYGGYASEGVKQVAELG SPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRHRHLMSFLTMLGPSPDWNVGLSAE DLCTKDCGWVQKVVQDLIPWDAGTDSGVTYESPNKPTVPQEKIRPLTSLDHPQSPFYDPEGGSIKLVARV VIERIARKGEQCNIVPDNIDDIVADLAPEEKEEDDTPETCIYSNWSPWSACSSSTCEKGKRMRQRMLKAQ LDLSVPCPDTQDFQPCMGPGCSDEDGSTCMMSDWITWSPCSVSCGMGTRSRERYVKQFPEDGSMCKVPTE ETEKCIVNEECSPSSCLVTEWGEWDECSASCGTGMKRRHRMIKMTPADGSMCKAETTEAEKCMMPECHTI PCLLSPWSEWSDCSVTCGKGMRTRQRMLKSAAELGDCNEELEQAEKCMLPECPIDCELTEWSQWSECNTS CGKGHMIRTRMIKIEPQFGGTACPETVQRTKCRVRKCLRGPGMEKRRWKEAREKRRSEQAKKNIDNEQYP VCRLKPWTAWTECSTLCGGGIQERYMMVKKRSKSTQFTSCKDKKELRACNVHPC >XP_034788091.1 spondin-1 [Pan paniscus] MPRFLRQTLGIQRRKINTAPPLIASSEETKQRCAGGSGQNQPSLLPLLRRGPPLLALLSFAWLSSAQLSA APRPPSRGGHGLRVADAGSELPLSAAPPPGRAFVGTTSGRSRVAKAGGRGTKLGAAKMRLSPAPLKLSRT PALLALALPLAAALAFSDETLDKVPKSEGYCSRILRAQGTRREGYTEFSLRVEGDPDFYKPGTSYRVTLS AAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAG TGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTFDGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKD YPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQ PLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTY ESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEE KDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCT MSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLMTEWGEWDECSAT CGMGMKKRHRMIKMSPADGSMCKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKS LAELGDCNEDLEQVEKCMLPECPIDCELTEWSQWSECNKSCGKGHVIRTRMIQMEPQFGGAPCPETVQRK KCRIRKCLRNPSIQKLRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKK RFKSSQFTSCKDKKEIRACNVHPC >XP_023095364.1 spondin-1 [Felis catus] MRLSPAPLRLSRSPALLALALPLAAALAFSDETLDKVPKSEGYCSRILRAQGTRREGYTEFSLRVEGDPD FYKPGISYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRR TRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSMFDGVTDKPILDCCACGTAKYRLT FYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVL TVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDL IPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPD NVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCM GPGCSDEDGSTCTMSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCL MTEWGEWDDCSATCGMGMKKRHRMVKMSPADGSACKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTC GKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPECPIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQ FGGAPCPETVQRKKCRIRKCLRNPSIQKLRWREARESRRNEQLREESGGEQFPGCRMRPWTAWSECTKLC GGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC >XP_027835169.1 spondin-1 [Ovis aries] MRLSPVLLRLSRGPALLALALPLAVALAFSDETLDKVPKSEGYCSRILRVQGTRREGYTEFSLRVEGDPD FYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRR TRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTFDGVTDKPILDCCACGTAKYRLT FYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVL TVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDL IPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPD NVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCM GPGCSDEDGSTCTMSEWITWSPCSISCGAGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCL TTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMCKAETSQAEKCMMPECHTIPCLLSLWSEWSDCSVTC GKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPECPIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQ FGGAPCPETVQRKKCRIRKCLRNPSLQNLRWREARESRRSEQLREESDGDQFPGCRMRPWTAWSECTKLC GGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC >XP_018893034.2 spondin-1 [Gorilla gorilla gorilla] MPRFLRQTLGIQRRKINTAAPLIASSEETKQRCAGGSGQNQPSLLPLLRRGPPLLALLSFAWLSSAQLSA APRPPSRGGHGLRVADAGSELPLSAAPPPGRAFVGTTSGRSRVAKAGGRGTKLGAAKMRLSPASLKLSRT PALLALALPLAAALAFSDETLDKVPKSEGYCSRILRAQGTRREGYTEFSLRVEGDPDFYKPGTSYRVTLS AAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAG TGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTFDGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKD YPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQ PLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTY ESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEE KDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCT MSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLMTEWGEWDECSAT CGMGMKKRHRMIKMSPADGSMCKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKS LAELGDCNEDLEQMEKCMLPECPIDCELTEWSQWSECNKSCGKGHVIRTRMIQMEPQFGGAPCPETVQRK KCRIRKCLRNPSIQKLRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKK RFKSSQFTSCKDKKEIRACNVHPC >XP_005499371.1 spondin-1 isoform X1 [Columba livia] MGAHLQPLALRLLALTFPLVAKGFSDETLEKAAKSEGYCSRILRAQGTRREGYNEFSLRVEGDPEFYKPG NSYRVTLSAATPAYFRGFTLIALKEGKEGDKEEDHAGAFQIIDEEETQFMSNCPVAVTESTPRRRTRIQV FWTAPPTGTGCVILKASIVQKRIIYFQDEGSLTKKICEQDSASEGVTDKPILDCCACGTAKYRLTFYGNW SEKTHPKDFPRRTNHWSAIIGSSHSKNYILWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKA KAQWPAWQPLNVRAAPSAEFSVDRHRHLMSFLTMLGPSPDWNVGLSAEDLCTKDCGWVQRVVQDLIPWDA GTDSGVTYESPNKPTVPQEKIRPLTSLDHPQSPFYDPEGGSIKLVARVVIERIARKGEQCNIVPDNIDDI VADLAPEEKEEDDTPETCIYSNWSPWSACSSSTCEKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCS DEDGSTCMMSDWITWSPCSVSCGMGTRSRERYVKQFPEDGSMCKVPTEETEKCVVNEECSPSSCLVTEWG EWDECSASCGMGMKRRHRMIKMTPADGSMCKAETTEAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMR TRQRILKSAAELGDCNEELEQAEKCMLPECPIDCELTEWSQWSECNTSCGKGHMIRTRMIKIEPQFGGTA CPETVQRTKCRLRKCLRGPGMEKRRWKEAREKRRSEQAKKNIDSEQYPVCRLKPWTAWTECSTFCGGGIQ ERYMMVKKRSKSTQFTSCKDKKELRACNVHPC >XP_017915073.1 PREDICTED: spondin-1 [Capra hircus] MRLSPVLLRLSRGPALLALALPLAVALAFSDETLDKVPKSEGYCSRILRVQGTRREGYTEFSLRVEGDPD FYKPGTSYRVTLSAAPPSYFRGFTLIALKENRDGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRR TRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTFDGVTDKPILDCCACGTAKYRLT FYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVL TVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDL IPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPD NVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCM GPGCSDEDGSTCTMSEWITWSPCSISCGAGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCL TTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMCKAETSQAEKCMMPECHTIPCLLSLWSEWSDCSVTC GKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPECPIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQ FGGAPCPETVQRKKCRIRKCLRNPSLQNLRWREARESRRSEQLREESDGDQFPGCRMRPWTAWSECTKLC GGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC >XP_006028011.1 spondin-1 [Alligator sinensis] MGLHPQALLAWPLLALAFPSVALGFSDETLEKATKSEGYCSRILRAQGTRREGYNEFSLRVEGDPEFYKP GNSYRVTLSAATPAYFRGFTLIALKEGKEGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQ VFWTAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSAFEGVTDKPILDCCACGTAKYRLTFYGN WSEKTHPKDFPRRTNHWSAIIGSSHSKNYILWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIK AKAQWPAWQPVNVRAAPSAEFSVDRHRHLMSFLTMLGPSPDWNVGLSAEDLCTKDCGWVQKVVQDLIPWD AGTDSGVTYESPNKPTVPQEKIRPLTSLDHPQSPFYDPEGGSIKLVARVVIERIARKGEQCNIVPDNVDD IVADLAPEEKEEDDTPETCIYSNWSPWSACSSSTCEKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGC SDEDGSTCMMSEWITWSPCSVSCGMGTRSRERYVKQFPEDGSMCKVPTEETEKCIVNEECAPSSCLVTEW GEWDECSASCGMGMKKRYRMIKMTPADGSMCKTETTEAEKCMMPECHTIPCMLSPWSEWSDCSVTCGKGM RTRQRMLKSAAELGDCNEELEQVEKCMLPECPIDCELTEWSHWSECNKSCGKGHMIRTRMIKMEPQFGGA PCPETVQRKKCRIRKCLRNPSIEKRRWKEAREKRRSEQAKKDIDSEQYPGCKMRPWTAWSECTKLCGGGI QERFMIVKKRFKNTQFTSCKDKKEIRACNVHPC >XP_014457833.1 PREDICTED: spondin-1 [Alligator mississippiensis] MGLHPQALLAWPLLALAFPSVALGFLDETLEKATKSEGYCSRILRAQGTRREGYNEFSLRVEGDPEFYKP GNSYRVTLSAATPAYFRGFTLIALKEGKEGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQ VFWTAPPAGTRCVILKASIVQKRIIYFQDEGSLTKKLCEQDSAFEGVTDKPILDCCACGTAKYRLTFYGN WSEKTHPKDFPRRTNHWSAIIGSSHSKNYILWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIK AKAQWPAWQPVNVRAAPSAEFSVDRHRHLMSFLTMLGPSPDWNVGLSAEDLCTKDCGWVQKVVQDLIPWD AGTDSGVTYESPNKPTVPQEKIRPLTSLDHPQSPFYDPEGGSIKLVARVVIERIARKGEQCNIVPDNVDD IVADLAPEEKEEDDTPETCIYSNWSPWSACSSSTCEKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGC SDEDGSTCMMSEWITWSPCSVSCGMGTRSRERYVKQFPEDGSMCKVPTEETEKCIVNEECAPSSCLVTEW GEWDECSASCGMGMKKRYRMIKMTPADGSMCKTETTEAEKCMMPECHTIPCMLSPWSEWSDCSVTCGKGM RTRQRMLKSAAELGDCNEELEQVEKCMLPECPIDCELTEWSHWSECNKSCGKGHMIRTRMIKMEPQFGGA PCPETVQRKKCRIRKCLRNPSIEKRRWKEAREKRRSEQAKKDIDSEQYPGCKMRPWTAWSECTKLCGGGI QERFMIVKKRFKNTQFTSCKDKKEIRACNVHPC >XP_020728710.1 spondin-1 [Odocoileus virginianus texanus] MRLSPVLLRLSRGPALLALALPLAVALAFSDETLDKVPKSEGYCSRILRAQGTRREGYTEFRLRVEGDPD FYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRR TRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTFDGVTDKPILDCCACGTAKYRLT FYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVL TVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKLVQDL IPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPD NVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCM GPGCSDEDGSTCTMSEWITWSPCSISCGTGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCL TTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMCKAETSQAEKCMMPECHTIPCLLSLWSEWSDCSVTC GKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPECPIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQ FGGAPCPETVQRKKCRIRKCLRNPSIQNLRWREARESRRSEQLREESDGDQFPGCRMRPWTAWSECTKLC GGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC >XP_040184219.1 LOW QUALITY PROTEIN: spondin-1 [Rana temporaria] MGLLVQALYLSYVAVTCLSVVSGFTDETVEKAVKSEGYCSRILRAQGSTRKEGYHEFSLRVEGDPEYYKP GSTYRVTLSATTPAYFRGFTLIALKEGKEGEKEEDHAGSFQIIDDEETQFMSNCPVAVTESTPRRRTRIQ VLWTAPSIGTGCVILKASIVQKKIIYFQDEGSLTKRMCELDVTSEGANEKTIPDCCACGTAKYRLTFYGN WSEKAHAKDYPRRANHWSAIIGGSHSKSYVLWEYGGYASDGVKQVAELGSPVKMEEEIRQKGDDVLTVIK AKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLAMLGPSPDWNVGLSAEDLCTKECGWVQRVVQDLIPWD AGTDSGVSYESPNKPTIPQDKIRPLTSLDHPQSPFYDPEGGPIVPVARVVIERIARKGEQCNIVPDNVDD IVADLVAEEKERKIDTPETCLSSNWSPWSACSSAHVRKGKRMRQAMLKAQLDLSVXLPDTQDFEPCMGPG CSVDDASTCMMSEWIMWSPCSASCGXGMRSRERYVKLFPEDGSLCKVPTEETEKCIVNEECEPSSCIVTE WGEWEECSATCGMGMKKRHRMIKMTPADGSMCKTETSEVEKCMMPECHTIPCVLSPWSDWSDCSVTCGKG SRTRQRMLKSPAELGDCNEELKQVEKCMLPECPINCELTEWSHWSECNKSCGKGHMIRTRMITLEPQFGG GNCPETVQRKKCRVRKCQKNSGGEKRRLKDAREKRRSERTNEEVDGEHSPVCKMKPWTTWTECSKYCGGG IQERFMTVKKRFKSSQFTSCKDKKEIRACNVHPC >XP_039254629.1 spondin-1-like [Styela clava] MSQKQRDSKDSGMRCKMNTSPKACLAMRRFCVNSQMKSFCFLMQIMCVVISFRPSHSQEFFPIDFTNCDFNTEPTRPDFV LPRSGDNGFSVKIEGMPEYYESEKSYTVTISSTHPATFRGFALAAVHANNYSLPAGNFKLLNPSSTKKHPSCSNIVTQTT LGKKASVQFVWDSPAPGFGCVQFKAVIIQKGKIWYRNEDKLTQTLCETIDSSSARVAHICCSCGSAQYRMTFYGLWSPQT HPKDYPGYSTHWSNVIGASHNDRYTIWDYGQYATDGVKKVAEWGWPNAVENEIRAQGDSVISVIKTRAQWPAFQPRNIRE PPSAMFDVDASRHLVSLLTMLGPSPDWNVGITKESMCTSQCGWINTKSYDLTPWDAGTDSGVSYLSPNSPTNPQDRIRAL TSSDDTESPFYDPLGRPIEPVARVVLERISISGDQCGPSPVSNSAPRSTGIDILSSPSVIEPPLTSCLYGEWSEWSQCGV TCGWGIKMRTKSLINKLLPSASCKPSITEKEICKGAAFCDNEDDSTVCLYSEWTKWSDCTAPCGSDALRFRTRELQWPSE PKNCHEPLKEMRFDCNTEPCELDVCEYGTWSDWMPCSTQCGIGQTLRKKFSIQSTEKCESPVMEISKCMASTDCAAPVGF DVPSGCSYSPWTGWMPCPVTCGVGETFRKRVLDFSTPDIHCDEFQMERTKCMTSESCPEIERLDNFGTQHCEYSEWSEWM PCSASCDVGNTLRKRFLKKTNTVANCEELHMETVQCYMPPCSVMIPKEDSLPHATQKSCIYGEWTAWMPCSVTCGRGETL RKRFLKKSLDISQTCDGFEMETNRCTVPGSCEVVVPKHEDVVTDWSSCSVTCGFGEKSRTVIKENCDSEDCKVVEIEECF VDARCPVDCQLSDWSEWSPCQGCEPKSARHHRKVATSTKSFQVRKRERLIKPKLGGAKCGRRKERRKCVCPS >XP_038071797.1 spondin-1-like [Patiria miniata] MARIFTKMFTILSFYSLTLLAGTLGASRRACSRLPGDFTVPKRPGDNGYRIRISGHPSFYVPGQEYLVTLSSTPPVSFRE FTFACLLVEDDATSAGHFEIVDDRLAQFSPDTINCPELLIHTSKASKTSVTFRWIAPPAGTGCVNFKAAAVQKKQIWYKD ERGLTLWLCEEDVAASVPPQTNTVDEDANIECCACHTAKYTVTMRGLWSQETHPKDFPGGHGDHWSDLIGASHTKDYTIW KYGGYASLGVQRVAEWGSPTTLEREILAQTRNIKTVIRSRGLWPARGNMSAVLSVNRTHNLVSTLSMIGPSPDWCVGVSR VNLCTADCDWLQRLEIDLLPWDAGTDSGITFRSDNAPTVPIEPIHPITSSFPSNPLGAFYDPMGRPIPPMAILVFERTDN TLYDDLGEVVCEVDVGGPDATHTGGGGMPPKEGMMPPKEGMMPPKAGTMMPPKEGMMPPKAGTMMPPKEGMMPPKEGMIP SPDGEIMPPKPGMMNKGGELSNVTTPMMKKPVPEGDITMPPKVMPNEGEDIPVTMPPKHAKTGGRQPIDCMMSPWSDWTE CSRSCGKGTMRRQRMVKQKARHGGQACGKQKEKKNCSTGPCPRDCMMSDWGEWTPCSVTCGNDGTQIRMRKIKKKARGSG QPCGPRREERVCGTPIEC >XP_003251296.1 spondin-1 [Apis mellifera] MLLLTVTACLVITVQAGCPMRPTAEQTSASRTTGDGGYRILVSGKADKYIPNAVYTISLQGSQTHERLQQFTHFTLSVNS QHAPSNPTARVGYFQLFPDGLTTFNEDCVNTISEASDYPKNEVQVMWRAPPSGSGCVIFTAMVLENNVRWYAEDGALTKT FCEMDSSEVEALDGEKCCACDEAKYSLIMEGIWSNVTHPKDFPFSVWLTHFSDLIGASHVPSFSFWGKDHVATDGFRQLA EWGSASGVETELRANSNKLRTLIKAAGLWYPNVNSNTTTNFRVDRKRPMISVASMFGPSPDWVVGVSKLNLCRKDCSWTK SEIIDLYPWDAGTDNGISYMSPNSETTPREKMKPITTLYPEDPRSPFYDPSGRPMLPLARLYLTREKIIPRGCDEEVLQQ QVAQLEVAENTEDTVRPECQTTEYTGWSSCSVSCGKGLRMRTRSYLMPEKAAMFKCNRQLVSKEMCVSSIPECSGEEDTD DGVGSLAGGNNDAFCETTDWGHWSECSSSCGVGIKMRTRRFKDRMGRKRCPHVYLVEKVKCMEPACSPGLEEQIDPACKV TDWSDWSPCSASCGKGVKLRTRLLMVDPSKQQECSSRMELVQQRPCLDQADCTFDMATAKVVCMEEPNAGPCRGYFQRWA FVPQKLMCVPFVYGGCRGNRNNFLTAEECNNTCGIVRAILSGQPLNTTDVQVAPISPALPPVHCVVSGWSPWTPCSVSCG TGRVTSFRTIQQEARNGGNPCPKKLQRRSRCQLAPCE >XP_030844169.1 spondin-1 [Strongylocentrotus purpuratus] MGAKKLFLGTFLLFVTIWIVSGQEEESCDPVMVPNIPKRNGDNGYRIRVDRLPTDYVPGQEYRELKFIFKRYPMCACIQW KKRRFIGLPLLLDWMAASCVLKIYFFLSSLITVLLQSTTPVSFREFFLVATKGSAPNEAAGDFVITDRLKVRFSRTCSRA LTHTFSSSKTSISAQWLAPPAGAGCVNFRAGVIQKKTVWFAEDGDLTLQLCERESAGNGPAPPPTLDPHACCAPPHEEAK YRFTFVSTWTPQTHPRQYPTGNGNHWSDLIGASHGSDYTIWEYGQYASYGIKMVAEWGSPYRLEREIKEEGDNVKTVIFS RGLFPAYGPRLRNMTSYFKTDSQRNLVSAVSMMGPSPDWCVGISKENLCTADCGWVERKVFYLQPWDAGTDSGIMYNSSN SPLDPPDPIRPITSSDPDNPRASFYNPNGGPIGSLATVVIERVSIRNRSNTETEHGTGSQGGVHGGMPPKKPMMGGNPTM PPKVMGQPDPTMPPKVMGGHDPTMPPKVMGGHDLTMPPKVMGRPDPTMPPKVMRGRDPTMPSKVMAQEPTMPPKQMGVIT MPPKTIEIIPEGDIQTMPPKRRGKVVDCMMTAWGEWSECSKSCGKGKMLRQRMIKQRPRNGGEECGQTKERQSCNVARCT SVDRDCRMSEWGPWSDCSVSCGGEMGIEFRMRDVARRARGDGAPCDPLKEMRACSANPC >NP_477435.1 fat-spondin [Drosophila melanogaster] MGQSLPLLIRLIVVIWLTISMVTACPRAPTHLNHGRRTRGDNGYKLIVADGPNGYVPGKTYNLLLLGSRTHLKVQHFTHF TITAEAHTGARRPQAASPRRVGRFQLFSDSLTQFNDRCVNTVSEADDLPKTEVQVMWVAPESGSGCVSLSAMVYEGPRAW FADDGNLSTVICERKPDAAAAQKECCACDEAKYSFVFEGIWSNETHPKDYPFAIWLTHFSDVIGASHESNFSFWGENHIA TAGFRSLAEWGSPAALETELRANGPKLRTLIKAAGLWYPNVNQNTSSKFRVDRKHPKVSLVSMFGPSPDWVVGISGLDLC TEDCSWKESMDFDLFPWDAGTDSGISYMSPNSETQPPERMYRITTMYPEDPRAPFYNPKSREMTPLAKLYLRREKIVSRN CDDEFLQALQLEVSDDAEEQDTRAECRVGDYSAWSPCSVSCGKGIRMRSRQYLYPAAADQNKCARQLVAKEMCVAAIPEC ADGPAQSKDRDDDEGENLANSQSLVGSNGEGAGLCKTSPWSVWSECSASCGIGITMRTRTFVNHLGRKRCPHITIVEKNK CMRPDCTYEQVELPDPQCPTSQWSDWSPCSSTCGRGVTIRTRLLLLENGPDKESCTQRMELHQQKECVNPIDCHINAEQA KDICVQAPDPGPCRGTYMRYAYDPQNQHCYSFTYGGCRGNRNNFLTENDCLNTCNVLRSPYSSRVDQPRACVLSDWSVWS PCSVSCGVGVSESRRYVVTEPQNGGQPCSKRLVKSRSCAMPAC >NP_495473.2 F-spondin [Caenorhabditis elegans] MLRFVAILQFILLLLLIFSCNADEAKCTIKPYEAKGDKSPGSNGYVIEINGTTTKSMDISKGFVPGEIYKVSIRGWRTQY TVKTFRGFVVSSLFEDNTSAGSWQVVKGHGDARISPGCRQSGVSHANLKSKTSVHMMWKAPEVSSGCVVFRASVIETKYI WFTEAEGLTVKLCIQKGTQILKPVDDPSATCCACDIAQYDLEFTGIWSKNTHPKDYPTLEHLTHFTDMLGSSHSSNYSLW TIGGISTDGMKEIAEWGNTYKAEAEAKAKASEVRSLMKVKGLWFPDVQGTTKSQFVVNKYHHFVSLATMFGPSPDWCVGL SSVNLCLPDCTWAEERTFELQPFDAGTDSGPTYMSPNEPTEPREPIHWITTKLNPLSPFYNSKSDTIPTLAKVILRRKNV TSSECKSDDILKAEAHNITNTSEDEEYKDRRECMMTQWEPWSLCSATCGKGIRIRSRVYVFPIKAQVFHCHRQTTEKQFC NAKINECENSEAFSSKCQVSSWGSWGECSVQCGHGMRSRNRTFLNPATKSGDCSVDLERKDICVGENGDDCNVTPDPLCK TTAWSDWSPCSASCDEGVRVRTRLFFYSEHEKRCMHVNLQEKDTCVMQSCRRFIEINSEEICQEDKQAGQCAGNFPRYWY NHEKTQCERFIFTGCKGNRNQFETEEECKQICLPGYEKSKSLIPNNQLLEDFGNTEVDDGGERVDCEVSKWTAWGSCSVS CGRGKKSRSRHVVKLARNGGHQCSEHLMQELQCRLRPCPVKLTCQVGPWSRWSPCSVSCGEGSQTRRRRVVRARNDDWEE IECDDAETEVRQCTGRHQC >XP_031569176.1 spondin-2-like isoform X1 [Actinia tenebrosa] MFLARASFIISLNIILAVAESTIENQTCSGEDCKLNSRTEVGRTPPQPVKANDLKCCACGQATYRMTFVGKWSRLTHPRH FPGPMSSWSALIGCSHSNEYHMWRYGNLASLGVQRLGEWGSTSKLEEEMRKQGNKVLNIIKMPGLWWGVGRSVIEFRADQ THSLLSVMSRIVPSPDWYVGVDSLNLCHVNCTWKNEETVDLFPLDAGTDDGINFISVNARSNPQQPIRRIDTRLHNHPMS SFYLPDNDAIRPFAQIKIERLGVSGSCLRSNMKGPFPPKPARIDCQVSRWSSWTPCSVTCGLGKQVRGRDVIVQPMHDGI PCPNLYDYKICDLQTCDDNNNNKCLVSAWSTWSKCTGTCGIGFKVRKRTIIRQPALGNKTCPKLIKKRRCRLSPCQKDRG RASAADCVVSAWSSWSECNRQCNRGKKKRTRQILNKAKDGGRRCPRLQEKRKCLVRKCPKK >XP_043337550.1 spondin-1 [Cervus canadensis] MRLSPVLLRLSRGPALLALALPLAVALAFSDETLDKVPKSEGYCSRILRVQGTRREGYTEFRLRVEGDPDFYKPGTSYRV TLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILK ASIVQKRIIYFQDEGSLTKKLCEQDSTFDGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHS KNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMM GPSPDWNVGLSAEDLCTKECGWVQKLVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQV ARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPC PDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSISCGTGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCL TTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMCKAETSQAEKCMMPECHTIPCLLSLWSEWSDCSVTCGKGMRTRQRM LKSLAELGDCNEELEQVEKCMLPECPIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQFGGTPCPETVQRKKCRIRKC LRNPSIQNLRWREARESRRSEQLREESDGDQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIR ACNVHPC >KAF4009007.1 hypothetical protein G4228_000364 [Cervus hanglu yarkandensis] MISSPDPGNSASQNKHHRAANRQLRNKTALRWGSGQNQPSLLLLLRRGPPFLALLGQHGLRVASTSSELRCPPGLCQVSF PRGPLRAGVVWRQPAARAQSWGPARMRLSPVLLRLSRGPALLALALPLAVALAFSDETLDKVPKSEGYCSRILRVQGTRR EGYTEFRLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTES TPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTFDGVTDKPILDCCACGTAKYRLTFYGNW SEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPL NVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKLVQDLIPWDAGTDSGVTYESPNKPTIPQEK IRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACS SSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSISCGTGMRSRERYVKQFPEDG SVCTLPTEETEKCTVNEECSPSSCLTTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMCKAETSQAEKCMMPECHTIPC LLSLWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPECPIDCELTEWSQWSECNKSCGKGHMIRTRMI QMEPQFGGTPCPETVQRKKCRIRKCLRNPSIQNLRWREARESRRSEQLREESDGDQFPGCRMRPWTAWSECTKLCGGGIQ ERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC >XP_018115643.1 spondin-1 [Xenopus laevis] MGLIFQPLFWQFVATTYALMVLGFLDETVEKAIKSEGYCSRILRAQGGTRKEGYHEFSLRVEGDPDFYKPGNTYRVTLLA ASPAYFRGFTLIALKEGKEGEKEEDHAGSFQIIDEEDTQFMTNCPVAVTESTPRRRTRIQVFWTAPQIGTGCVILKASIV QKKIIYFQDEGSLTKRMCEPDLTLEGGNEKTMPDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKEYV LWEYGGQASDGVKQVAELGSPVKMEEEIRQKGDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRSRHLMSFLAMMGPSP DWNVGLTSEDLCTKECGWVQKVIQDLIPWDAGTDSGVTYESPNKPTIPQDKIRPLTSLDHPQSPFYDPEGGPIIPIARVV IERIARKGEQCNIIPDNVDDIVADLVTEEKDEDDTPETCIYSNWSPWSACSSATCDKGKRMRQRMLKAQLDLSVPCPDTQ DFEPCMGPGCSDDEASTCMMSEWITWSPCSASCGMGMRSRERYVKQFPEDGSLCKVPTEETEKCIVNEECEPSSCIVTEW AEWEECSATCGMGMKKRHRMIKMTPADGSMCKADTTEVEKCMMPECHTIPCVLSPWSEWSDCSVTCGKGTRTRQRMLKSP AELGDCNEELKQVEKCMLPECPISCELTEWSYWSECNKSCGKGHMIRTRMITMEPQFGGAVCPETVQRKKCRLRKCQKSS GNERRHLKDAREKRRSEKIKEDSDGEQYPVCKMKPWTAWTECTKFCGGGIQERFMTVKKRFKSSQFTSCKDKKEIRACNV HPC >XP_015808377.1 PREDICTED: spondin-1 isoform X1 [Nothobranchius furzeri] MPASGLDPRVVLLLCFISSAACNTFAFTEEPSDRAVKADSYCSRILRAQSNRKEVNNEFRLRVEGDPESYQPGSTYRVSL TASSPSYFRGFTLIATREGAEGDRDEDYAGNFQIIDEEETQFMTNCPPAVTESTPRRRTSIQVFWTAPPSGTGCVLLKAS IVQKRIIYFQDEGALTKRMCEKESLYGDSTDRPLLDCCACGTAKYRVTFYGNWSEKIHPKDYPRRANHWSALIGASHSKN YVLWEYGGTASEGVKQVAELGSPVKMEEEIRQKGDDVLTVIKMKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGP SPDWNVGLSAEDLCTKECGWAQKVVQDLIPWDAGTDGGVSYESPNKPTLPQDKIRPLTSLDHPQSPFYDPEGGAITPVAR VMVERIARKGEQCNIVPDNVDDIVADIAQEEKEEDDTPETCIYSNWSPWSACSSATCEKGKRMRQRMLKAQLDLSVPCPH TQDFEPCMGPGCSDEDASTCMMSEWITWSPCSASCGTGTRSRERYVKQFPDDGSVCTLPTEETENCVVNEDCLPSSCLVT EWAEWDVCSATCGLGMKRRERMVKMPPADGSICGAEVLEVEKCMMPECHTIPCLLTPWSEWSDCSVTCGKGLRTRQRILK SPAELGECTEELEQVEKCMLPECPIDCSLSEWTEWSECNKSCGKGHTIRTRIVKLEPQFGGDPCSQTVQRKKCKVRRCTR GQGNSEEKRRRKEQREKQRGKQGRAEGATEHPGCRMRPWSSWTECTKLCGGGIQERLMSIKQKFKTVQLSSCKDRKEIRA CNVHPC >XP_023809284.1 spondin-1 isoform X2 [Oryzias latipes] MKASGLHPAVMLLLCFISSAACTSLGFTEEPFERAGKADGYCSRILRAQSNRKESNNEFRLRVEGDPDSYQPGSTYRVNV IASSPSYFRGFTLIALKEGAGGDKDDDYAGNFRIIDEDETQFMTNCPHAVTESTPRRRNNIQVFWTAPPTGSGCVLLKAS IVQKKIIFFQDEGPLTKQMCEKESLYGDATDKPLLDCCACGTAKYRVTFYGNWSEKIHPKDYPRRANHWSAIIGASHSKN YVLWEYGGSASDGVKQVAELGSPVKMEEEIRQKGDDVLTVIKMKAQWPAWQPLNVRAAPSAEFSVDRIRHLMSFLTMMGP SPDWNVGLSAENLCTKECGWVQKVVQDLIPWDAGTDSGVSYESSNKPTVPQEKIRPLTSLDHPQSPFYDPEGGAITPVAR VVVERIARKGEQCNIVPDNVDDIVADIAQEEKEEDDTPETCIYSNWSPWSACSSATCEKGKRMRQRMLKAQLDLSVPCPH TQDFEPCMGPGCSDEDGSTCMMSEWITWSPCSMSCGAGIRSRERYVKQFPDDGSICTLPTEETENCVVNEECSPSSCLVT EWGEWDACSATCGLGMKRRERMVKMPPADGSICGAEVLEVEKCMMPECHTIPCLLTPWSEWSDCSVTCGKGSRTRHRVLK SPLELGECTEDLEQVEKCMLPECPIDCAMSDWTEWSECNKSCGKGHTIRTRVVTMEPQFGGDPCPETIQRKKCKVRKCSR GQGNSDDKKRRKEQREKRRSKQVKTEVTSEHPGCKMRPWSSWTECTKQCGGGIQERLMTVKQKFKTAQLSSCKERKEIRA CNVHPC >XP_030271163.1 spondin-1 isoform X2 [Sparus aurata] MSVAGRHARVLLLLCFVSTAACNMFAFTEEPSERAGKSDGYCSRILRAQSNRKEVNNEFRLRVEGDPESYQPGSTYRVLL TASSPSYFRGFTIIAQREGAEGDRDEDYIGNFQIIDEEETQFMTNCPPAVTESTPRRHTSIQVFWTAPRSGSGCVLLKAS IVQKRIIYFQDEGSLTKRMCEKESLYGDTTEKPLLDCCACGTAKYRVTFYGNWSEKIHPKDYPRRANHWSAIIGASHSKS YVLWEYGGLASDGVKQVAELGSPVKMEEEIRQKGDDVLTVIKMKAQWPAWQPLNVRAAPSAEFSVDRTRHIMSFLTMLGP SPDWNVGLSAEDLCTKECGWAQKVVQDLIPWDAGTDSGVTYESPNKPTVPQEKIRPLTSLDHPQSPFYDPEGGAITPVAR VVVERIARKGEQCNIVPDNVDDIVADIAQEEKEEDDTPETCIYSNWSPWSACSSATCEKGKRMRQRMLKAQLDLSVPCPH TQDFEPCMGPGCSDEDASTCMLSEWITWSPCSASCGIGSRSRERYVKQFPDDGSVCTLPTEETETCVVNEECSPSSCLVT EWGEWDVCSATCGLGMKRRERLVKMPPTDGSICGAEVLEVEKCMMPECHTIPCMLTPWSDWSDCSVTCGKGLRTRQRKLT SPVELGDCTEELEQVEKCMLPECPIDCVMSEWTEWSECNKSCGKGHTIRTRMVKLEPQFGGDSCTETIQRKKCKIRKCNR GQANSDEKKRRKEQREKRRSKTSRVDATSEHPGCKMRPWSSWTDCTKLCGGGIQERLMTVKQRFKTAQLSSCKDRKEIRA CNVHPC >KAB0370901.1 hypothetical protein FD755_017310 [Muntiacus reevesi] MVITLSKNHASGGSVPPYSFQSWFPGGQTHLSLKSELEVSEPSSLLENLPKSIDFLRIVKKTGFESEKPTQFLKKTHIYF YSFITLNSIFNYKGNKYFEVWTIPHSGYRSGQNALAGNDLCTPCTKQKVLRWLHPLVGQGVGVVLRLQQSKGSLTYRDLR RVCANTDQGYWAQCRHQNSSWRRHRKVWSFQGYAALRGGAGCAPRNQQWPEMETKNPPSLSPSHPLAIVMVSAFVSRRAA PSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKLVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLT SLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCD KGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCTMSEWITWSPCSISCGTGMRSRERYVKQFPEDGSVCTL PTEETEKCTVNEECSPSSCLTTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMCKAETSQAEKCMMPECHTIPCLLSLW SEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPECPIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQ FGGTPCPETVQRKKCRIRKCLRNPSIQNLRWREARESRRSEQLREESDGDQFPGCRLRPWTAWSECTKLCGGGIQERYMT VKKRFKSSQFTSCKDKKEIRACNVHPC >KAB0347695.1 hypothetical protein FD754_012552 [Muntiacus muntjak] MDCSPPGSSVHGILQARILEWVAIPLSRGPSRPRDQTHISCIGRQVLYHCTTWEQFLKKTHIYFYSFITLNSIFNYKGNK YFEHITQLPYYWVFRAGIGCPRTSYPLKPTKPTVQVRLQQSKGSLTYASRKASLPWPLFSGPHLTLQCCSTQHRKVWSFQ GYTALRGGRNQQWPEMETKNPPSLSPSHPLAIVMVSAFVSRRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLC TKECGWVQKLVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCN IVPDNVDDIVADLAPEEKDEDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSD EDGSTCTMSEWITWSPCSISCGTGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLTTEWGEWDECSATCGM GMKKRHRMVKMSPADGSMCKAETSQAEKCMMPECHTIPCLLSLWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEELEQ VEKCMLPECPIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQFGGTPCPETVQRKKCRIRKCLRNPSIQNLRWREARE SRRSEQLREESDGDQFPGCRLRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC >OWK18058.1 SPON1 [Cervus elaphus hippelaphus] MVSTFVSRRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKLVQDLIPWDAGTDSGVTYESPNKP TIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKEYPTSPRLVGQQGFSCSHVNLSRGRASHSSDRLSGKTP HILFPDDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGPGCSDEDGSTCTMSEWITWS PCSISCGTGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLTTEWGEWDECSATCGMGMKKRHRMVKMSPAD GSMCKAETSQAEKCMMPECHTIPCLLSLWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPECPIDCEL TEWSQWSECNKSCGKGHMIRTRMIQMEPQFGGTPCPETVQRKKCRIRKCLRNPSIQNLRWREARESRRSEQLREESDGDQ FPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNVHPC
Mafft alignment of selected proteins >sp|Q9HCB6|SPON1_HUMAN Spondin-1 OS=Homo sapiens OX=9606 GN=SPON1 PE=1 SV=2 ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MRLSPAPLK--------LSRTPALLALALPLAAALA FSDETLDK-VPKSEGYCSRILR----AQ-GTRREGYTEFSLRVEGD-------PDFYKPG TSYR-------------------------------------------------VTLSAAP P----SYFRGFTLIALRENREGDKEED----HAGTFQIID-EEETQFMS---NCPVA-VT ESTPRRRTRIQVFWIAPPAGTGC----VILKASIVQKRIIYFQDEGSLTKKLCEQDSTFD -GVTDKP------ILDCCAC--GTAKYRLTFYGNWSEKTHPKDYPR--RANHWSAIIGGS HSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVR AAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTD SGVTYESPNKPTIPQEKIRPLTSL--DHPQSPFYDPEGGSITQVARVVIERIARK----- -------GEQCNIV------PDNVDDIVADLAPEEKDE-D-DTPETCIYSNWSPWSACSS STCDKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CTMSEWITWSPCSISCGM-GMRSRERYVKQFPEDGSVCTLPT EETEKCT--VNEECSPSS-------CLMTEWGEWDECSATCGMGMK---KRHRMIKMNPA DGSM-C--KAETSQAEKCMMPECHTIP--------CLLSPWS--------------EWSD CSVTCGKGMRTRQRMLKSLAELG-DCNEDLEQVEKCMLPE-CP----------------- --IDCELTEWSQWSECNKSCGK--GHVIRTRMIQMEPQFGGAPCPET-VQRKKCRIRKCL RNPSI--QKLRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQ-ERY MTVKKRFKSSQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >tr|F1R2Z9|F1R2Z9_DANRE F-spondin OS=Danio rerio OX=7955 GN=spon1b PE=4 SV=3 ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MMDKDGLVV------------LLVFLNVFL-IHSDA FKRDTAER-HSRSEGGFCRILRT--QAR-SARRDGQNEFRLKVEGE-------PETYQPG STYR-------------------------------------------------VSLYASS P----SYFRGFTLIALKEGREGVSPDD----YAGTFKLID-ESDTQFMT---NCPPA-VT ESIPRRRTRIQVFWTAPPSGSGC----VTLKASVVQRRIIFFQDEGSLTKRLCEKDPV-- -AITEKP------AQECCAC--GTAKYRVTFYGNWSEKLHPKDYPR--RANHWSALIGAS HTRSYVLWEYGGFASEGVKQVSEYGSPVKMEEEIRQKGDDVMTVIKTKAQWPAWQPLNIR AAPSAEFSVDRVRHLMSFLTMLGPSPDWNVGLSGEDLCTRDCGWVQKLVKDLVPWDAGTD SGVSYESPNKPSIPQERIRPLTSL--DHPQSPFYDPSGGPMTPLGRVVVERIARK----- -------GEQCNTV------PDTIDDIVADIAQEEKEEGD-NTPETCIYSNWSPWSACSS STCDKGRRMRQRMLKAQ-LDPNLPC--LHTQDFEPCMG--PGC------SEEEA------ ---------------ST-CMMSEWISWSPCSASCGM-GMRSRERYVKQFPEDGSSCTLPT EETEKCV--VNDDCSPSS-------CVVTEWGEWEPCSVSCGLGMR---RRERMMKMDAS DGSP-C--RVQMAEAEKCMMPECNAVV--------CMLSPWS--------------DWGE CSVSCGVGMRTRQRMLKTPVKPG-QCPDELEQVEKCMLPE-CP----------------- --TDCMLSEWSAWSECNKSCGK--GHMIRSRMVKLEPQFGGLPCPET-VQRKKCKIRKCS RGSRA-SEKRKRQEVSDRRRAKQSRESVAEESTVVCPIRPWSSWTECTKPCDGGTQ-ERV MTIKKKGKSSQHNHCKN-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >NP_742064.2 spondin-1 precursor [Rattus norvegicus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MRLSPAPLR--------LSRGPALLALALPLAAALA FSDETLDK-VAKSEGYCSRILR----AQ-GTRREGYTEFSLRVEGD-------PDFYKPG SSYR-------------------------------------------------VTLSAAP P----SYFRGFTLIALKENREGDKEED----HAGTFQIID-EEETQFMS---NCPVA-VT ESTPRRRTRIQVFWIAPPTGTGC----VILKASIVQKRIIYFQDEGSLTKKLCEQDPTLD -GVTDRP------ILDCCAC--GTAKYRLTFYGNWSEKTHPKDYPR--RANHWSAIIGGS HSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPVNVR AAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTD SGVTYESPNKPTIPQEKIRPLTSL--DHPQSPFYDPEGGSITQVARVVIERIARK----- -------GEQCNIV------PDNVDDIVADLAPEEKDE-D-DTPETCIYSNWSPWSACSS STCEKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CTMSEWITWSPCSVSCGM-GMRSRERYVKQFPEDGSVCMLPT EETEKCT--VNEECSPSS-------CLVTEWGEWDDCSATCGMGMK---KRHRMVKMSPA DGSM-C--KAETSQAEKCMMPECHTIP--------CLLSPWS--------------EWSD CSVTCGKGMRTRQRMLKSLAELG-DCNEDLEQAEKCMLPE-CP----------------- --IDCELSEWSQWSECNKSCGK--GHMIRTRTIQMEPQFGGAPCPET-VQRKKCRARKCL RSPSI--QKLRWREARESRRSEQLREESDGEQFPGCRMRPWTAWSECTKLCGGGIQ-ERY MTVKKRFKSSQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >NP_663559.1 spondin-1 precursor [Mus musculus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MRLSPVSLR--------LSRGPALLALALPLAAALA FSDETLDK-VTKSEGYCSRILR----AQ-GTRREGYTEFSLRVEGD-------PDFYKPG SSYR-------------------------------------------------VTLSAAP P----SYFRGFTLIALKENQEGDKEED----HAGTFQIID-EEETQFMS---NCPVA-VT ESTPRRRTRIQVFWIAPPTGTGC----VILKASIVQKRIIYFQDEGSLTKKLCEQDPTLD -GVTDRP------ILDCCAC--GTAKYRLTFYGNWSEKTHPKDYPR--RANHWSAIIGGS HSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPVNVR AAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTD SGVTYESPNKPTIPQEKIRPLTSL--DHPQSPFYDPEGGSITQVARVVIERIARK----- -------GEQCNIV------PDNVDDIVADLAPEEKDE-D-DTPETCIYSNWSPWSACSS STCEKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CTMSEWITWSPCSVSCGM-GMRSRERYVKQFPEDGSVCMLPT EETEKCT--VNEECSPSS-------CLVTEWGEWDDCSATCGMGMK---KRHRMVKMSPA DGSM-C--KAETSQAEKCMMPECHTIP--------CLLSPWS--------------EWSD CSVTCGKGMRTRQRMLKSLAELG-DCNEDLEQAEKCMLPE-CP----------------- --IDCELSEWSQWSECNKSCGK--GHMIRTRTIQMEPQFGGVPCPET-VQRKKCRTRKCL RSPSV--QKLRWREARESRRSEQLREESDGEQFPGCRMRPWTAWSECTKLCGGGIQ-ERY MTVKKRFKSSQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >NP_777168.1 spondin-1 precursor [Bos taurus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MRLSPVLLR--------LSRGPALLALALPLAVALA FSDETLDK-VPKSEGYCSRILR----VQ-GTRREGYTEFSLRVEGD-------PDFYKPG TSYR-------------------------------------------------VTLSAAP P----SYFRGFTLIALKENREGDKEED----HAGTFQIID-EEETQFMS---NCPVA-VT ESTPRRRTRIQVFWIAPPAGTGC----VILKASIVQKRIIYFQDEGSLTKKLCEQDSTFD -GVTDKP------ILDCCAC--GTAKYRLTFYGNWSEKTHPKDYPR--RANHWSAIIGGS HSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVR AAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTD SGVTYESPNKPTIPQEKIRPLTSL--DHPQSPFYDPEGGSITQVARVVIERIARK----- -------GEQCNIV------PDNVDDIVADLAPEEKDE-D-DTPETCIYSNWSPWSACSS STCDKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CTMSEWITWSPCSISCGT-GTRSRERYVKQFPEDGSVCTLPT EETEKCT--VNEECSPSS-------CLTTEWGEWDECSATCGMGMK---KRHRMVKMSPA DGSM-C--KAETSQAEKCMMPECHTIP--------CLLSLWS--------------EWSD CSVTCGKGMRTRQRMLKSLAELG-DCNEELEQVEKCMLPE-CP----------------- --IDCELTEWSQWSECNKSCGK--GHMIRTRMIQMEPQFGGTPCPET-VQRKKCRIRKCL RNPSI--QNLRWREARESRRSEQLREESDGDQFPGCRMRPWTAWSECTKLCGGGIQ-ERY MTVKKRFKSSQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >NP_990182.1 spondin-1 precursor [Gallus gallus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MAARLRPL------------ALRLLARTFP-LVARG FSDETLEK-AAKSEGYCSRILR----AQ-GTRREGYNEFSLRVEGD-------PEFYKPG NSYR-------------------------------------------------VTLSAAT P----AYFRGFTLIALKEGKEGDKEED----HAGTFQIID-EEETQFMS---NCPVA-VT ESTPRRRTRIQVFWTAPPTGTGC----VILKASIVQKRIIYFQDEGSLTKRICEQDSASE -GVTDKP------TLDCCAC--GTAKYRLTFYGNWSEKTHPKDFPR--RTNHWSAIIGSS HSKNYILWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVR AAPSAEFSVDRHRHLMSFLTMLGPSPDWNVGLSAEDLCTKDCGWVQKVVQDLIPWDAGTD SGVTYESPNKPTVPQEKIRPLTSL--DHPQSPFYDPEGGSIKLVARVVLERIARK----- -------GEQCNFV------PDNIDDIVADLAPEEKEE-D-DTPETCIYSNWSPWSACSS STCEKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CMMSDWITWSPCSVSCGM-GTRSRERYVKQFPEDGSMCKVPT EETEKCI--VNEECSPSS-------CLVTEWGEWDECSASCGTGMK---RRHRMIKMTPA DGSM-C--KAETTEAEKCMMPECHTIP--------CLLSPWS--------------EWSD CSVTCGKGMRTRQRMLKSAAELG-DCNEELEQAEKCMLPE-CP----------------- --IDCELTEWSQWSECNTSCGK--GHMIRTRMIKIEPQFGGTACPET-VQRTKCRVRKCL RGPGM--EKRRWKEAREKRRSEQAKKNIDNEQYPVCRLKPWTAWTECSTLCGGGIQ-ERY MMVKKRSKSTQFTSCKD-KKELRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >XP_508295.3 spondin-1 [Pan troglodytes] MPRFLRQTLGIQRRKINTAAPLIASSEETKQRCAG-----------GSGQNQPSLLPLLR RGPPLLALLSFAWLSSAQLSAAPRPPSRGGHGLRVADASSELPLSAAPPPGRAFVGTTSG RSRVA----NAGGRGTKLGA--AKMRLSPAPLK--------LSRTPALLALALPLAAALA FSDETLDK-VPKSEGYCSRILR----AQ-GTRREGYTEFSLRVEGD-------PDFYKPG TSYR-------------------------------------------------VTLSAAP P----SYFRGFTLIALKENREGDKEED----HAGTFQIID-EEETQFMS---NCPVA-VT ESTPRRRTRIQVFWIAPPAGTGC----VILKASIVQKRIIYFQDEGSLTKKLCEQDSTFD -GVTDKP------ILDCCAC--GTAKYRLTFYGNWSEKTHPKDYPR--RANHWSAIIGGS HSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVR AAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTD SGVTYESPNKPTIPQEKIRPLTSL--DHPQSPFYDPEGGSITQVARVVIERIARK----- -------GEQCNIV------PDNVDDIVADLAPEEKDE-D-DTPETCIYSNWSPWSACSS STCDKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CTMSEWITWSPCSISCGM-GMRSRERYVKQFPEDGSVCTLPT EETEKCT--VNEECSPSS-------CLMTEWGEWDECSATCGMGMK---KRHRMIKMSPA DGSM-C--KAETSQAEKCMMPECHTIP--------CLLSPWS--------------EWSD CSVTCGKGMRTRQRMLKSLAELG-DCNEDLEQVEKCMLPE-CP----------------- --IDCELTEWSQWSECNKSCGK--GHVIRTRMIQMEPQFGGAPCPET-VQRKKCRIRKCL RNPSI--QKLRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQ-ERY MTVKKRFKSSQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >XP_534067.2 spondin-1 [Canis lupus familiaris] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MRLSPAPPG--------LSPSPALLALALPLAAALA FSDETLDK-VPKSEGYCSRILR----AQ-GTRREGYTEFSLRVEGD-------PDFYKPG TSYR-------------------------------------------------VTLSAAP P----SYFRGFTLIALKENREGDKEED----HAGTFQIID-EEETQFMS---NCPVA-VT ESTPRRRTRIQVFWIAPPAGTGC----VILKASIVQKRIIYFQDEGSLTKKLCEQDSMFD -GVTDKP------ILDCCAC--GTAKYRLTFYGNWSEKTHPKDYPR--RANHWSAIIGGS HSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVR AAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTD SGVTYESPNKPTIPQEKIRPLTSL--DHPQSPFYDPEGGSITQVARVVIERIARK----- -------GEQCNIV------PDNVDDIVADLAPEEKDE-D-DTPETCIYSNWSPWSACSS STCDKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CTMSEWITWSPCSISCGM-GMRSRERYVKQFPEDGSVCTLPT EETEKCT--VNEECSPSS-------CLMTEWGEWDECSATCGMGMK---KRHRMVKMSPA DGSM-C--KAETSQAEKCMMPECHTIP--------CLLSPWS--------------EWSD CSVTCGKGMRTRQRMLKSLAELG-DCNEELEQVEKCMLPE-CP----------------- --IDCELTEWSQWSECNKSCGK--GHMIRTRMIQMEPQFGGAPCPET-VQRKKCRIRKCL KNPSI--QKLRWREARESRRGEQLREESDGEQFPGCRMRPWTAWSECTKLCGGGIQ-ERY MTVKKRFKSSQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >XP_002708869.1 PREDICTED: spondin-1 [Oryctolagus cuniculus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MRLSPAPLR--------LSRTLALLALALPLAAALA FSDETLDK-VAKSEGYCSRILR----AQ-GTRREGYTEFSLRVEGD-------PDFYKPG TSYR-------------------------------------------------VTLSAAP P----SYFRGFTLIALKENREGDKEED----HAGTFQIID-EEETQFMS---NCPVA-VT ESTPRRRTRIQVFWIAPPTGTGC----VILKASIVQKRIIYFQDEGSLTKKLCEQDSTFD -GVTDKP------ILDCCAC--GTAKYRLTFYGNWSEKTHPKDYPR--RANHWSAIIGGS HSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVR AAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTD SGVTYESPNKPTIPQEKIRPLTSL--DHPQSPFYDPEGGSIIQVARVVIERIARK----- -------GEQCNIV------PDNVDDIVADLAPEEKDE-D-DTPETCIYSNWSPWSACSS STCDKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CTMSEWITWSPCSISCGT-GMRSRERYVKQFPEDGSVCTLPT EETEKCT--VNEECSPSS-------CLMTEWGEWDECSATCGMGMK---KRHRMVKMSPA DGSM-C--KAETSQTEKCMMPECHTIP--------CLLSPWS--------------EWSD CSVTCGKGMRTRQRMLKSLAELG-DCNEELEQVEKCMLPE-CP----------------- --IDCELTEWSQWSECNKSCGK--GHMIRTRMIQMEPQFGGAPCPET-VQRKKCRVRKCL RNPSI--QKLRWREARESRRGEQLREESDGEQFPGCRMRPWTAWSECTKLCGGGIQ-ERY MTVKKRFKSSQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >XP_002822053.2 spondin-1 [Pongo abelii] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MRLSPATLK--------LSRTPALLALALPLAAALA FSDETLDK-VPKSEGYCSRILR----AQ-GTRREGYTEFSLRVEGD-------PDFYKPG TSYR-------------------------------------------------VTLSAAP P----SYFRGFTLIALKENREGDKEED----HAGTFQIID-EEETQFMS---NCPVA-VT ESTPRRRTRIQVFWIAPPAGTGC----VILKASIVQKRIIYFQDEGSLTKKLCEQDSTFD -GVTDKP------ILDCCAC--GTAKYRLTFYGNWSEKTHPKDYPR--RANHWSAIIGGS HSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVR AAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTD SGVTYESPNKPTIPQEKIRPLTSL--DHPQSPFYDPEGGSITQVARVVIERIARK----- -------GEQCNIV------PDNVDDIVADLAPEEKDE-D-DTPETCIYSNWSPWSACSS STCDKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CTMSEWITWSPCSISCGM-GMRSRERYVKQFPEDGSVCTLPT EETEKCT--VNEECSPSS-------CLMTEWGEWDECSATCGMGMK---KRHRMIKMSPA DGSM-C--KAETSQAEKCMMPECHTIP--------CLLSPWS--------------EWSD CSVTCGKGMRTRQRMLKSLAELG-DCNEDLEQVEKCMLPE-CP----------------- --IDCELTEWSQWSECNKSCGK--GHVIRTRMIQMEPQFGGAPCPET-VQRKKCRIRKCL RNPSI--QKLRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQ-ERY MTVKKRFKSSQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >XP_003123014.4 spondin-1 [Sus scrofa] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MRLSPASVK--------LSGSPALLALALPLAAALA FSDETLDK-VPKSEGYCSRILR----VQ-GTRREGYTEFSLRVEGD-------PDFYKPG TSYR-------------------------------------------------VTLSAAP P----SYFRGFTLIALKENREGDKEED----HAGTFQIID-EEETQFMS---NCPVA-VT ESTPRRRTRIQVFWIAPPAGTGC----VILKASIVQKRIIYFQDEGSLTKKVCEQDSTFD -GVTDRP------ILDCCAC--GTAKYRLTFYGNWSEKTHPKDYPR--RANHWSAIIGGS HSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVR AAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTD SGVTYESPNKPTIPQEKIRPLTSL--DHPQSPFYDPEGGSITQVARVVIERIARK----- -------GEQCNIV------PDNVDDIVADLAPEEKDE-D-DTPETCIYSNWSPWSACSS STCDKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CTMSEWITWSPCSISCGT-GMRSRERYVKQFPEDGSVCTLPT EETEKCT--VNEECSPSS-------CLMTEWGEWDECSATCGMGMK---KRHRMVKMSPA DGSM-C--KAETSQAEKCMMPECHTIP--------CLLSPWS--------------EWSD CSVTCGKGMRTRQRMLKSLAELG-DCNEELEQVEKCMLPE-CP----------------- --IDCELTEWSQWSECNKSCGK--GHMIRTRMIQMEPQFGGAPCPET-VQRKKCRIRKCL RNPSI--QKLRWREARESRRSEQLREESDGEQFPGCRMRPWTAWSECTKLCGGGIQ-ERY MTVKKRFKSSQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >XP_031409214.1 spondin-1 [Meleagris gallopavo] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---MCFTS-SAKDAAFPHPI-----------ATDDVNTWCV------------------- -----------------------------------------------------VTLSAAT P----AYFRGFTLIALKEGKEGDKEED----HAGTFQIID-EEETQFMS---NCPVA-VT ESTPRRRTRIQVFWTAPPTGTGC----VILKASIVQKRIIYFQDEGSLTKRICEQDSASE -GVTDKP------ILDCCAC--GTAKYRLTFYGNWSEKTHPKDFPR--RTNHWSAIIGSS HSKNYILWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVR AAPSAEFSVDRHRHLMSFLTMLGPSPDWNVGLSAEDLCTKDCGWVQKVVQDLIPWDAGTD SGVTYESPNKPTVPQEKIRPLTSL--DHPQSPFYDPEGGSIKLVARVVIERIARK----- -------GEQCNIV------PDNIDDIVADLAPEEKEE-D-DTPETCIYSNWSPWSACSS STCEKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CMMSDWITWSPCSVSCGM-GTRSRERYVKQFPEDGSMCKVPT EETEKCI--VNEECSPSS-------CLVTEWGEWDECSASCGTGMK---RRHRMIKMTPA DGSM-C--KAETTEAEKCMMPECHTIP--------CLLSPWS--------------EWSD CSVTCGKGMRTRQRMLKSAAELG-DCNEELEQAEKCMLPE-CP----------------- --IDCELTEWSQWSECNTSCGK--GHMIRTRMIKIEPQFGGTACPET-VQRTKCRVRKCL RGPGM--EKRRWKEAREKRRSEQAKKNIDNEQYPVCRLKPWTAWTECSTLCGGGIQ-ERY MMVKKRSKSTQFTSCKD-KKELRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >XP_034788091.1 spondin-1 [Pan paniscus] MPRFLRQTLGIQRRKINTAPPLIASSEETKQRCAG-----------GSGQNQPSLLPLLR RGPPLLALLSFAWLSSAQLSAAPRPPSRGGHGLRVADAGSELPLSAAPPPGRAFVGTTSG RSRVA----KAGGRGTKLGA--AKMRLSPAPLK--------LSRTPALLALALPLAAALA FSDETLDK-VPKSEGYCSRILR----AQ-GTRREGYTEFSLRVEGD-------PDFYKPG TSYR-------------------------------------------------VTLSAAP P----SYFRGFTLIALKENREGDKEED----HAGTFQIID-EEETQFMS---NCPVA-VT ESTPRRRTRIQVFWIAPPAGTGC----VILKASIVQKRIIYFQDEGSLTKKLCEQDSTFD -GVTDKP------ILDCCAC--GTAKYRLTFYGNWSEKTHPKDYPR--RANHWSAIIGGS HSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVR AAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTD SGVTYESPNKPTIPQEKIRPLTSL--DHPQSPFYDPEGGSITQVARVVIERIARK----- -------GEQCNIV------PDNVDDIVADLAPEEKDE-D-DTPETCIYSNWSPWSACSS STCDKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CTMSEWITWSPCSISCGM-GMRSRERYVKQFPEDGSVCTLPT EETEKCT--VNEECSPSS-------CLMTEWGEWDECSATCGMGMK---KRHRMIKMSPA DGSM-C--KAETSQAEKCMMPECHTIP--------CLLSPWS--------------EWSD CSVTCGKGMRTRQRMLKSLAELG-DCNEDLEQVEKCMLPE-CP----------------- --IDCELTEWSQWSECNKSCGK--GHVIRTRMIQMEPQFGGAPCPET-VQRKKCRIRKCL RNPSI--QKLRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQ-ERY MTVKKRFKSSQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >XP_023095364.1 spondin-1 [Felis catus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MRLSPAPLR--------LSRSPALLALALPLAAALA FSDETLDK-VPKSEGYCSRILR----AQ-GTRREGYTEFSLRVEGD-------PDFYKPG ISYR-------------------------------------------------VTLSAAP P----SYFRGFTLIALKENREGDKEED----HAGTFQIID-EEETQFMS---NCPVA-VT ESTPRRRTRIQVFWIAPPAGTGC----VILKASIVQKRIIYFQDEGSLTKKLCEQDSMFD -GVTDKP------ILDCCAC--GTAKYRLTFYGNWSEKTHPKDYPR--RANHWSAIIGGS HSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVR AAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTD SGVTYESPNKPTIPQEKIRPLTSL--DHPQSPFYDPEGGSITQVARVVIERIARK----- -------GEQCNIV------PDNVDDIVADLAPEEKDE-D-DTPETCIYSNWSPWSACSS STCDKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CTMSEWITWSPCSISCGM-GMRSRERYVKQFPEDGSVCTLPT EETEKCT--VNEECSPSS-------CLMTEWGEWDDCSATCGMGMK---KRHRMVKMSPA DGSA-C--KAETSQAEKCMMPECHTIP--------CLLSPWS--------------EWSD CSVTCGKGMRTRQRMLKSLAELG-DCNEELEQVEKCMLPE-CP----------------- --IDCELTEWSQWSECNKSCGK--GHMIRTRMIQMEPQFGGAPCPET-VQRKKCRIRKCL RNPSI--QKLRWREARESRRNEQLREESGGEQFPGCRMRPWTAWSECTKLCGGGIQ-ERY MTVKKRFKSSQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >XP_027835169.1 spondin-1 [Ovis aries] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MRLSPVLLR--------LSRGPALLALALPLAVALA FSDETLDK-VPKSEGYCSRILR----VQ-GTRREGYTEFSLRVEGD-------PDFYKPG TSYR-------------------------------------------------VTLSAAP P----SYFRGFTLIALKENREGDKEED----HAGTFQIID-EEETQFMS---NCPVA-VT ESTPRRRTRIQVFWIAPPAGTGC----VILKASIVQKRIIYFQDEGSLTKKLCEQDSTFD -GVTDKP------ILDCCAC--GTAKYRLTFYGNWSEKTHPKDYPR--RANHWSAIIGGS HSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVR AAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTD SGVTYESPNKPTIPQEKIRPLTSL--DHPQSPFYDPEGGSITQVARVVIERIARK----- -------GEQCNIV------PDNVDDIVADLAPEEKDE-D-DTPETCIYSNWSPWSACSS STCDKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CTMSEWITWSPCSISCGA-GMRSRERYVKQFPEDGSVCTLPT EETEKCT--VNEECSPSS-------CLTTEWGEWDECSATCGMGMK---KRHRMVKMSPA DGSM-C--KAETSQAEKCMMPECHTIP--------CLLSLWS--------------EWSD CSVTCGKGMRTRQRMLKSLAELG-DCNEELEQVEKCMLPE-CP----------------- --IDCELTEWSQWSECNKSCGK--GHMIRTRMIQMEPQFGGAPCPET-VQRKKCRIRKCL RNPSL--QNLRWREARESRRSEQLREESDGDQFPGCRMRPWTAWSECTKLCGGGIQ-ERY MTVKKRFKSSQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >XP_018893034.2 spondin-1 [Gorilla gorilla gorilla] MPRFLRQTLGIQRRKINTAAPLIASSEETKQRCAG-----------GSGQNQPSLLPLLR RGPPLLALLSFAWLSSAQLSAAPRPPSRGGHGLRVADAGSELPLSAAPPPGRAFVGTTSG RSRVA----KAGGRGTKLGA--AKMRLSPASLK--------LSRTPALLALALPLAAALA FSDETLDK-VPKSEGYCSRILR----AQ-GTRREGYTEFSLRVEGD-------PDFYKPG TSYR-------------------------------------------------VTLSAAP P----SYFRGFTLIALKENREGDKEED----HAGTFQIID-EEETQFMS---NCPVA-VT ESTPRRRTRIQVFWIAPPAGTGC----VILKASIVQKRIIYFQDEGSLTKKLCEQDSTFD -GVTDKP------ILDCCAC--GTAKYRLTFYGNWSEKTHPKDYPR--RANHWSAIIGGS HSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVR AAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTD SGVTYESPNKPTIPQEKIRPLTSL--DHPQSPFYDPEGGSITQVARVVIERIARK----- -------GEQCNIV------PDNVDDIVADLAPEEKDE-D-DTPETCIYSNWSPWSACSS STCDKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CTMSEWITWSPCSISCGM-GMRSRERYVKQFPEDGSVCTLPT EETEKCT--VNEECSPSS-------CLMTEWGEWDECSATCGMGMK---KRHRMIKMSPA DGSM-C--KAETSQAEKCMMPECHTIP--------CLLSPWS--------------EWSD CSVTCGKGMRTRQRMLKSLAELG-DCNEDLEQMEKCMLPE-CP----------------- --IDCELTEWSQWSECNKSCGK--GHVIRTRMIQMEPQFGGAPCPET-VQRKKCRIRKCL RNPSI--QKLRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQ-ERY MTVKKRFKSSQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >XP_005499371.1 spondin-1 isoform X1 [Columba livia] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGAHLQPL------------ALRLLALTFP-LVAKG FSDETLEK-AAKSEGYCSRILR----AQ-GTRREGYNEFSLRVEGD-------PEFYKPG NSYR-------------------------------------------------VTLSAAT P----AYFRGFTLIALKEGKEGDKEED----HAGAFQIID-EEETQFMS---NCPVA-VT ESTPRRRTRIQVFWTAPPTGTGC----VILKASIVQKRIIYFQDEGSLTKKICEQDSASE -GVTDKP------ILDCCAC--GTAKYRLTFYGNWSEKTHPKDFPR--RTNHWSAIIGSS HSKNYILWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVR AAPSAEFSVDRHRHLMSFLTMLGPSPDWNVGLSAEDLCTKDCGWVQRVVQDLIPWDAGTD SGVTYESPNKPTVPQEKIRPLTSL--DHPQSPFYDPEGGSIKLVARVVIERIARK----- -------GEQCNIV------PDNIDDIVADLAPEEKEE-D-DTPETCIYSNWSPWSACSS STCEKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CMMSDWITWSPCSVSCGM-GTRSRERYVKQFPEDGSMCKVPT EETEKCV--VNEECSPSS-------CLVTEWGEWDECSASCGMGMK---RRHRMIKMTPA DGSM-C--KAETTEAEKCMMPECHTIP--------CLLSPWS--------------EWSD CSVTCGKGMRTRQRILKSAAELG-DCNEELEQAEKCMLPE-CP----------------- --IDCELTEWSQWSECNTSCGK--GHMIRTRMIKIEPQFGGTACPET-VQRTKCRLRKCL RGPGM--EKRRWKEAREKRRSEQAKKNIDSEQYPVCRLKPWTAWTECSTFCGGGIQ-ERY MMVKKRSKSTQFTSCKD-KKELRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >XP_017915073.1 PREDICTED: spondin-1 [Capra hircus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MRLSPVLLR--------LSRGPALLALALPLAVALA FSDETLDK-VPKSEGYCSRILR----VQ-GTRREGYTEFSLRVEGD-------PDFYKPG TSYR-------------------------------------------------VTLSAAP P----SYFRGFTLIALKENRDGDKEED----HAGTFQIID-EEETQFMS---NCPVA-VT ESTPRRRTRIQVFWIAPPAGTGC----VILKASIVQKRIIYFQDEGSLTKKLCEQDSTFD -GVTDKP------ILDCCAC--GTAKYRLTFYGNWSEKTHPKDYPR--RANHWSAIIGGS HSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVR AAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTD SGVTYESPNKPTIPQEKIRPLTSL--DHPQSPFYDPEGGSITQVARVVIERIARK----- -------GEQCNIV------PDNVDDIVADLAPEEKDE-D-DTPETCIYSNWSPWSACSS STCDKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CTMSEWITWSPCSISCGA-GMRSRERYVKQFPEDGSVCTLPT EETEKCT--VNEECSPSS-------CLTTEWGEWDECSATCGMGMK---KRHRMVKMSPA DGSM-C--KAETSQAEKCMMPECHTIP--------CLLSLWS--------------EWSD CSVTCGKGMRTRQRMLKSLAELG-DCNEELEQVEKCMLPE-CP----------------- --IDCELTEWSQWSECNKSCGK--GHMIRTRMIQMEPQFGGAPCPET-VQRKKCRIRKCL RNPSL--QNLRWREARESRRSEQLREESDGDQFPGCRMRPWTAWSECTKLCGGGIQ-ERY MTVKKRFKSSQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >XP_006028011.1 spondin-1 [Alligator sinensis] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGLHPQALL-----------AWPLLALAFP-SVALG FSDETLEK-ATKSEGYCSRILR----AQ-GTRREGYNEFSLRVEGD-------PEFYKPG NSYR-------------------------------------------------VTLSAAT P----AYFRGFTLIALKEGKEGDKEED----HAGTFQIID-EEETQFMS---NCPVA-VT ESTPRRRTRIQVFWTAPPAGTGC----VILKASIVQKRIIYFQDEGSLTKKLCEQDSAFE -GVTDKP------ILDCCAC--GTAKYRLTFYGNWSEKTHPKDFPR--RTNHWSAIIGSS HSKNYILWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPVNVR AAPSAEFSVDRHRHLMSFLTMLGPSPDWNVGLSAEDLCTKDCGWVQKVVQDLIPWDAGTD SGVTYESPNKPTVPQEKIRPLTSL--DHPQSPFYDPEGGSIKLVARVVIERIARK----- -------GEQCNIV------PDNVDDIVADLAPEEKEE-D-DTPETCIYSNWSPWSACSS STCEKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CMMSEWITWSPCSVSCGM-GTRSRERYVKQFPEDGSMCKVPT EETEKCI--VNEECAPSS-------CLVTEWGEWDECSASCGMGMK---KRYRMIKMTPA DGSM-C--KTETTEAEKCMMPECHTIP--------CMLSPWS--------------EWSD CSVTCGKGMRTRQRMLKSAAELG-DCNEELEQVEKCMLPE-CP----------------- --IDCELTEWSHWSECNKSCGK--GHMIRTRMIKMEPQFGGAPCPET-VQRKKCRIRKCL RNPSI--EKRRWKEAREKRRSEQAKKDIDSEQYPGCKMRPWTAWSECTKLCGGGIQ-ERF MIVKKRFKNTQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >XP_014457833.1 PREDICTED: spondin-1 [Alligator mississippiensis] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGLHPQALL-----------AWPLLALAFP-SVALG FLDETLEK-ATKSEGYCSRILR----AQ-GTRREGYNEFSLRVEGD-------PEFYKPG NSYR-------------------------------------------------VTLSAAT P----AYFRGFTLIALKEGKEGDKEED----HAGTFQIID-EEETQFMS---NCPVA-VT ESTPRRRTRIQVFWTAPPAGTRC----VILKASIVQKRIIYFQDEGSLTKKLCEQDSAFE -GVTDKP------ILDCCAC--GTAKYRLTFYGNWSEKTHPKDFPR--RTNHWSAIIGSS HSKNYILWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPVNVR AAPSAEFSVDRHRHLMSFLTMLGPSPDWNVGLSAEDLCTKDCGWVQKVVQDLIPWDAGTD SGVTYESPNKPTVPQEKIRPLTSL--DHPQSPFYDPEGGSIKLVARVVIERIARK----- -------GEQCNIV------PDNVDDIVADLAPEEKEE-D-DTPETCIYSNWSPWSACSS STCEKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CMMSEWITWSPCSVSCGM-GTRSRERYVKQFPEDGSMCKVPT EETEKCI--VNEECAPSS-------CLVTEWGEWDECSASCGMGMK---KRYRMIKMTPA DGSM-C--KTETTEAEKCMMPECHTIP--------CMLSPWS--------------EWSD CSVTCGKGMRTRQRMLKSAAELG-DCNEELEQVEKCMLPE-CP----------------- --IDCELTEWSHWSECNKSCGK--GHMIRTRMIKMEPQFGGAPCPET-VQRKKCRIRKCL RNPSI--EKRRWKEAREKRRSEQAKKDIDSEQYPGCKMRPWTAWSECTKLCGGGIQ-ERF MIVKKRFKNTQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >XP_020728710.1 spondin-1 [Odocoileus virginianus texanus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MRLSPVLLR--------LSRGPALLALALPLAVALA FSDETLDK-VPKSEGYCSRILR----AQ-GTRREGYTEFRLRVEGD-------PDFYKPG TSYR-------------------------------------------------VTLSAAP P----SYFRGFTLIALKENREGDKEED----HAGTFQIID-EEETQFMS---NCPVA-VT ESTPRRRTRIQVFWIAPPAGTGC----VILKASIVQKRIIYFQDEGSLTKKLCEQDSTFD -GVTDKP------ILDCCAC--GTAKYRLTFYGNWSEKTHPKDYPR--RANHWSAIIGGS HSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVR AAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKLVQDLIPWDAGTD SGVTYESPNKPTIPQEKIRPLTSL--DHPQSPFYDPEGGSITQVARVVIERIARK----- -------GEQCNIV------PDNVDDIVADLAPEEKDE-D-DTPETCIYSNWSPWSACSS STCDKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CTMSEWITWSPCSISCGT-GMRSRERYVKQFPEDGSVCTLPT EETEKCT--VNEECSPSS-------CLTTEWGEWDECSATCGMGMK---KRHRMVKMSPA DGSM-C--KAETSQAEKCMMPECHTIP--------CLLSLWS--------------EWSD CSVTCGKGMRTRQRMLKSLAELG-DCNEELEQVEKCMLPE-CP----------------- --IDCELTEWSQWSECNKSCGK--GHMIRTRMIQMEPQFGGAPCPET-VQRKKCRIRKCL RNPSI--QNLRWREARESRRSEQLREESDGDQFPGCRMRPWTAWSECTKLCGGGIQ-ERY MTVKKRFKSSQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >XP_040184219.1 LOW QUALITY PROTEIN: spondin-1 [Rana temporaria] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGLLVQALY------------LSYVAVTCL-SVVSG FTDETVEK-AVKSEGYCSRILR----AQGSTRKEGYHEFSLRVEGD-------PEYYKPG STYR-------------------------------------------------VTLSATT P----AYFRGFTLIALKEGKEGEKEED----HAGSFQIID-DEETQFMS---NCPVA-VT ESTPRRRTRIQVLWTAPSIGTGC----VILKASIVQKKIIYFQDEGSLTKRMCELDVTSE -GANEKT------IPDCCAC--GTAKYRLTFYGNWSEKAHAKDYPR--RANHWSAIIGGS HSKSYVLWEYGGYASDGVKQVAELGSPVKMEEEIRQKGDDVLTVIKAKAQWPAWQPLNVR AAPSAEFSVDRTRHLMSFLAMLGPSPDWNVGLSAEDLCTKECGWVQRVVQDLIPWDAGTD SGVSYESPNKPTIPQDKIRPLTSL--DHPQSPFYDPEGGPIVPVARVVIERIARK----- -------GEQCNIV------PDNVDDIVADLVAEEKER-KIDTPETCLSSNWSPWSACSS AHVRKGKRMRQAMLKAQ-LDLSVXL--PDTQDFEPCMG--PGC------SVDDA------ ---------------ST-CMMSEWIMWSPCSASCGX-GMRSRERYVKLFPEDGSLCKVPT EETEKCI--VNEECEPSS-------CIVTEWGEWEECSATCGMGMK---KRHRMIKMTPA DGSM-C--KTETSEVEKCMMPECHTIP--------CVLSPWS--------------DWSD CSVTCGKGSRTRQRMLKSPAELG-DCNEELKQVEKCMLPE-CP----------------- --INCELTEWSHWSECNKSCGK--GHMIRTRMITLEPQFGGGNCPET-VQRKKCRVRKCQ KNSGG--EKRRLKDAREKRRSERTNEEVDGEHSPVCKMKPWTTWTECSKYCGGGIQ-ERF MTVKKRFKSSQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >XP_039254629.1 spondin-1-like [Styela clava] ------------------------------------------------------------ ----MSQKQ--------------------------------------------------- -------------RDSKDSGMRCKMNTSPKACLAMRRFCVNSQMKSFCFLMQIM-CVVIS FRPSHSQEFFPIDFTNCDFNTEPTRPDF-VLPRSGDNGFSVKIEGM-------PEYYESE KSYT-------------------------------------------------VTISSTH P----ATFRGFALAAVH----ANNYSL----PAGNFKLLN-PSSTKKHP---SCSNI-VT QTTLGKKASVQFVWDSPAPGFGC----VQFKAVIIQKGKIWYRNEDKLTQTLCETIDSSS -ARV---------AHICCSC--GSAQYRMTFYGLWSPQTHPKDYPG--YSTHWSNVIGAS HNDRYTIWDYGQYATDGVKKVAEWGWPNAVENEIRAQGDSVISVIKTRAQWPAFQPRNIR EPPSAMFDVDASRHLVSLLTMLGPSPDWNVGITKESMCTSQCGWINTKSYDLTPWDAGTD SGVSYLSPNSPTNPQDRIRALTSS--DDTESPFYDPLGRPIEPVARVVLERISIS----- -------GDQCGPSPVS---NSAPRSTGIDILSSPSVI-E-PPLTSCLYGEWSEWSQC-G VTCGWGIKMRTKSLINK-LLPSASCK-PSITEKEICKGA-AFC------DNEDD------ ---------------STVCLYSEWTKWSDCTAPCGSDALRFRTREL-QWPSEPKNCHEPL KEMRFDC--NTEPCELDV-------CEYGTWSDWMPCSTQCGIGQT---LRKK---FSIQ STEK-C--ESPVMEISKCMASTDCAAPVGFDVPSGCSYSPWT--------------GWMP CPVTCGVGETFRKRVLDFSTPDI-HCDEFQMERTKCMTSESCPEIERLDNFG-------- -TQHCEYSEWSEWMPCSASCDV--GNTLRKRFLKKT--NTVANCEELHMETVQCYMPPCS VMIPK-------------------EDSLPHATQKSCIYGEWTAWMPCSVTCGRGET-LRK RFLKKSLDISQ--TCDGFEMETNRCTVPGSCEVVVPKHEDVVTDWSSCSVTCGFGEKSRT VIKENCDSEDCKVVEIEECFVDARCPVDCQLSDWSEWSPCQGCEPKSARHHRKVATSTKS FQVRKRERLIKPKLGGAKCGRRKERRKCVCPS >XP_038071797.1 spondin-1-like [Patiria miniata] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MAR----IF----------TKMFTILSFYS-LTLLA GT-------LGASRRACSRLPG---DFT-VPKRPGDNGYRIRISGH-------PSFYVPG QEYL-------------------------------------------------VTLSSTP P----VSFREFTFACLL----VEDDAT----SAGHFEIVD-DRLAQFSPDTINCPEL-LI HTSKASKTSVTFRWIAPPAGTGC----VNFKAAAVQKKQIWYKDERGLTLWLCEEDVAAS -VPPQTNTVDEDANIECCAC--HTAKYTVTMRGLWSQETHPKDFPGG-HGDHWSDLIGAS HTKDYTIWKYGGYASLGVQRVAEWGSPTTLEREILAQTRNIKTVIRSRGLWPA------R GNMSAVLSVNRTHNLVSTLSMIGPSPDWCVGVSRVNLCTADCDWLQRLEIDLLPWDAGTD SGITFRSDNAPTVPIEPIHPITSSFPSNPLGAFYDPMGRPIPPMAILVFERTDNTL---- --------------------YDDLGEVVCEVDVGGPDA---------------------T HTGGGGMPPKEGMMPPK-EGMMPPKAGTMMPPKEGMMP--PKA----------------- -------------------------------------GTMMPPKEGMMPPKEGMIPSPD- ----------GEIMPPKP-------GMMNKGGELSNVTTPMMKKP----VPEGDITMPPK VMPN-------EGEDIPVTMPPKHAKT-GGRQPIDCMMSPWS--------------DWTE CSRSCGKGTMRRQRMVKQKARHGGQACGKQKEKKNCSTGP-CP----------------- --RDCMMSDWGEWTPCSVTCGND-GTQIRMRKIKKKARGSGQPCGPR-REERVCGTP--- ------------------------------------------------------------ ----------------------------IEC----------------------------- ------------------------------------------------------------ -------------------------------- >XP_003251296.1 spondin-1 [Apis mellifera] ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MLL-LTVTA CL-------VITVQAGCPMRPTA-EQTS-ASRTTGDGGYRILVSGK-------ADKYIPN AVYT-------------------------------------------------ISLQGSQ THERLQQFTHFTLSVNSQH-APSNPTA----RVGYFQLFP-DGLTTFNE---DCVNT-IS EASDYPKNEVQVMWRAPPSGSGC----VIFTAMVLENNVRWYAEDGALTKTFCEMDSSEV -EALD--------GEKCCAC--DEAKYSLIMEGIWSNVTHPKDFPFSVWLTHFSDLIGAS HVPSFSFWGKDHVATDGFRQLAEWGSASGVETELRANSNKLRTLIKAAGLWYP----NVN SNTTTNFRVDRKRPMISVASMFGPSPDWVVGVSKLNLCRKDCSWTKSEIIDLYPWDAGTD NGISYMSPNSETTPREKMKPITTLYPEDPRSPFYDPSGRPMLPLARLYLTREKII----- -------PRGCD--------EEVLQQQVAQLEVAENTE-D-TVRPECQTTEYTGWSSC-S VSCGKGLRMRTRSYLMPEKAAMFKCN-RQLVSKEMCVSSIPEC------SGEEDTDDGVG -----SLAGGNND--AF-CETTDWGHWSECSSSCGV-GIKMRTRRFKDRMGRKRCPHVYL VEKVKCM---EPACSPGLEEQIDPACKVTDWSDWSPCSASCGKGVK---LRTRLLMVDPS KQQE-CSSRMELVQQRPCLDQADCTFD-MATAKVVCMEEPNAGPCRGYFQRWAFVPQKLM CVPFVYGGCRGNRNNFLTAEECN-NTCGI----VRAILSG-QPL--NTTDVQVAPISPAL PPVHCVVSGWSPWTPCSVSCGT--GRVTSFRTIQQEARNGGNPCPKKLQRRSRCQLAPCE ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------- >XP_030844169.1 spondin-1 [Strongylocentrotus purpuratus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGA--KKLF------------LGTFLLFVT-IWIVS GQ----------EEESCDPVMV----PN-IPKRNGDNGYRIRVDRL-------PTDYVPG QEYRELKFIFKRYPMCACIQWKKRRFIGLPLLLDWMAASCVLKIYFFLSSLITVLLQSTT P----VSFREFFLVATK----GSAPNE----AAGDFVITD-RLKVRFSR---TCSRA-LT HTFSSSKTSISAQWLAPPAGAGC----VNFRAGVIQKKTVWFAEDGDLTLQLCERESAGN -GPAPPPTLD---PHACCAPPHEEAKYRFTFVSTWTPQTHPRQYPTG-NGNHWSDLIGAS HGSDYTIWEYGQYASYGIKMVAEWGSPYRLEREIKEEGDNVKTVIFSRGLFPAYGP-RLR -NMTSYFKTDSQRNLVSAVSMMGPSPDWCVGISKENLCTADCGWVERKVFYLQPWDAGTD SGIMYNSSNSPLDPPDPIRPITSSDPDNPRASFYNPNGGPIGSLATVVIERVSIR----- -----------------------------NRSNTETEH-G-TGSQGGVHGGMPPKKPM-- ---MGGNPTMPPKVMGQ-PDPTMPP--KVMGGHDPTMP--PKV----------------- ----------------------------------------MGGHDLTMPPKVMGRP---- ----------DPTMPPKV----------MRGRDPTMPSKVMAQEPTMPPKQMGVITMPPK TIEI-------IPEGDIQTMPPKRRGK-----VVDCMMTAWG--------------EWSE CSKSCGKGKMLRQRMIKQRPRNGGEECGQTKERQSCNVAR-CTSVD-------------- --RDCRMSEWGPWSDCSVSCGGEMGIEFRMRDVARRARGDGAPCDPL-KEMRACSANPC- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------- >NP_477435.1 fat-spondin [Drosophila melanogaster] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGQ--------------------SLPLLIR-LIVVI WL-------TISMVTACPRAPT--HLNH-GRRTRGDNGYKLIVADG-------PNGYVPG KTYN-------------------------------------------------LLLLGSR THLKVQHFTHFTITAEAHT-GARRPQAASPRRVGRFQLFS-DSLTQFND---RCVNT-VS EADDLPKTEVQVMWVAPESGSGC----VSLSAMVYEGPRAWFADDGNLSTVICERKPDAA -AA----------QKECCAC--DEAKYSFVFEGIWSNETHPKDYPFAIWLTHFSDVIGAS HESNFSFWGENHIATAGFRSLAEWGSPAALETELRANGPKLRTLIKAAGLWYP----NVN QNTSSKFRVDRKHPKVSLVSMFGPSPDWVVGISGLDLCTEDCSWKESMDFDLFPWDAGTD SGISYMSPNSETQPPERMYRITTMYPEDPRAPFYNPKSREMTPLAKLYLRREKIV----- -------SRNCD--------DEFL--QALQLEVSDDAE-EQDTRAECRVGDYSAWSPC-S VSCGKGIRMRSRQYLYPAAADQNKCA-RQLVAKEMCVAAIPECADGPAQSKDRDDDEGEN LANSQSLVGSNGEGAGL-CKTSPWSVWSECSASCGI-GITMRTRTFVNHLGRKRCPHITI VEKNKCM---RPDCTYEQVELPDPQCPTSQWSDWSPCSSTCGRGVT---IRTRLLLLENG PDKESCTQRMELHQQKECVNPIDCHIN-AEQAKDICVQAPDPGPCRGTYMRYAYDPQNQH CYSFTYGGCRGNRNNFLTENDCL-NTCNV----LRSPYS-----------------SRVD QPRACVLSDWSVWSPCSVSCGV--GVSESRRYVVTEPQNGGQPCSKRLVKSRSCAMPAC- ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------- >NP_495473.2 F-spondin [Caenorhabditis elegans] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MLR------------------FVAILQFIL-LLLLI FS-------CNADEAKCTIKPY---EAK-GDKSPGSNGYVIEINGTTTKSMDISKGFVPG EIYK-------------------------------------------------VSIRGWR TQYTVKTFRGFVVSSLFE------DNT----SAGSWQVVKGHGDARISP---GCRQSGVS HANLKSKTSVHMMWKAPEVSSGC----VVFRASVIETKYIWFTEAEGLTVKLCIQKGTQI LKPVDDP------SATCCAC--DIAQYDLEFTGIWSKNTHPKDYPTLEHLTHFTDMLGSS HSSNYSLWTIGGISTDGMKEIAEWGNTYKAEAEAKAKASEVRSLMKVKGLWFP----DVQ GTTKSQFVVNKYHHFVSLATMFGPSPDWCVGLSSVNLCLPDCTWAEERTFELQPFDAGTD SGPTYMSPNEPTEPREPIHWITTK--LNPLSPFYNSKSDTIPTLAKVILRRKNVT----- -------SSECKS-------DDILKAEAHNITNTSEDE-EYKDRRECMMTQWEPWSLC-S ATCGKGIRIRSRVYVFPIKAQVFHCH-RQTTEKQFCNAKINEC------ENSEA------ ----FS---------SK-CQVSSWGSWGECSVQCGH-GMRSRNRTFLNPATKSGDCSVDL ERKDICVGENGDDCNVTP----DPLCKTTAWSDWSPCSASCDEGVR---VRTRLFFYSEH EKR--C-MHVNLQEKDTCVMQSCRRFI-EINSEEICQEDKQAGQCAGNFPRYWYNHEKTQ CERFIFTGCKGNRNQFETEEECK-QICLPGYEKSKSLIPN-NQL---LEDFGNTEVDDGG ERVDCEVSKWTAWGSCSVSCGR--GKKSRSRHVVKLARNGGHQCSEHLMQELQCRLRPCP VKL-------------------------------TCQVGPWSRWSPCSVSCGEGSQTRRR RVVRARNDDWEEIECDDAETEVRQCTGRHQC----------------------------- ------------------------------------------------------------ -------------------------------- >XP_031569176.1 spondin-2-like isoform X1 [Actinia tenebrosa] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MFL--------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------ARASFIISL------------NIILA-VA ESTIENQTC---------SGEDC---------------------------KLNSRTEVGR -TPPQPVKAN---DLKCCAC--GQATYRMTFVGKWSRLTHPRHFPG--PMSSWSALIGCS HSNEYHMWRYGNLASLGVQRLGEWGSTSKLEEEMRKQGNKVLNIIKMPGLWWG------V GRSVIEFRADQTHSLLSVMSRIVPSPDWYVGVDSLNLCHVNCTWKNEETVDLFPLDAGTD DGINFISVNARSNPQQPIRRIDTRLHNHPMSSFYLPDNDAIRPFAQIKIERLGVS----- -------GSCLRS------------------NMKGPFP-PKPARIDCQVSRWSSWTPC-S VTCGLGKQVRGRDVIVQPMHDGIPC--PNLYDYKICDL--QTC------DDNNN------ ---------------NK-CLVSAWSTWSKCTGTCGI-GFKVRKRTIIRQPALGN------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------KTCPKLIKKRRCRLSP-CQK-----DRGRA------ SAADCVVSAWSSWSECNRQCNR--GKKKRTRQILNKAKDGGRRCPRL-QEKRKCLVRKCP KK---------------------------------------------------------- ------------------------------------------------------------ ------------------------------------------------------------ -------------------------------- >XP_043337550.1 spondin-1 [Cervus canadensis] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MRLSPVLLR--------LSRGPALLALALPLAVALA FSDETLDK-VPKSEGYCSRILR----VQ-GTRREGYTEFRLRVEGD-------PDFYKPG TSYR-------------------------------------------------VTLSAAP P----SYFRGFTLIALKENREGDKEED----HAGTFQIID-EEETQFMS---NCPVA-VT ESTPRRRTRIQVFWIAPPAGTGC----VILKASIVQKRIIYFQDEGSLTKKLCEQDSTFD -GVTDKP------ILDCCAC--GTAKYRLTFYGNWSEKTHPKDYPR--RANHWSAIIGGS HSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVR AAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKLVQDLIPWDAGTD SGVTYESPNKPTIPQEKIRPLTSL--DHPQSPFYDPEGGSITQVARVVIERIARK----- -------GEQCNIV------PDNVDDIVADLAPEEKDE-D-DTPETCIYSNWSPWSACSS STCDKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CTMSEWITWSPCSISCGT-GMRSRERYVKQFPEDGSVCTLPT EETEKCT--VNEECSPSS-------CLTTEWGEWDECSATCGMGMK---KRHRMVKMSPA DGSM-C--KAETSQAEKCMMPECHTIP--------CLLSLWS--------------EWSD CSVTCGKGMRTRQRMLKSLAELG-DCNEELEQVEKCMLPE-CP----------------- --IDCELTEWSQWSECNKSCGK--GHMIRTRMIQMEPQFGGTPCPET-VQRKKCRIRKCL RNPSI--QNLRWREARESRRSEQLREESDGDQFPGCRMRPWTAWSECTKLCGGGIQ-ERY MTVKKRFKSSQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >KAF4009007.1 hypothetical protein G4228_000364 [Cervus hanglu yarkandensis] M--------------ISSPDPGNSASQNKHHRAANRQLRNKTALRWGSGQNQPSLLLLLR RGPPFLALL-------------------GQHGLRVASTSSELRC----PPGLCQVSFPRG PLRAGVVWRQPAARAQSWGP--ARMRLSPVLLR--------LSRGPALLALALPLAVALA FSDETLDK-VPKSEGYCSRILR----VQ-GTRREGYTEFRLRVEGD-------PDFYKPG TSYR-------------------------------------------------VTLSAAP P----SYFRGFTLIALKENREGDKEED----HAGTFQIID-EEETQFMS---NCPVA-VT ESTPRRRTRIQVFWIAPPAGTGC----VILKASIVQKRIIYFQDEGSLTKKLCEQDSTFD -GVTDKP------ILDCCAC--GTAKYRLTFYGNWSEKTHPKDYPR--RANHWSAIIGGS HSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVR AAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKLVQDLIPWDAGTD SGVTYESPNKPTIPQEKIRPLTSL--DHPQSPFYDPEGGSITQVARVVIERIARK----- -------GEQCNIV------PDNVDDIVADLAPEEKDE-D-DTPETCIYSNWSPWSACSS STCDKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CTMSEWITWSPCSISCGT-GMRSRERYVKQFPEDGSVCTLPT EETEKCT--VNEECSPSS-------CLTTEWGEWDECSATCGMGMK---KRHRMVKMSPA DGSM-C--KAETSQAEKCMMPECHTIP--------CLLSLWS--------------EWSD CSVTCGKGMRTRQRMLKSLAELG-DCNEELEQVEKCMLPE-CP----------------- --IDCELTEWSQWSECNKSCGK--GHMIRTRMIQMEPQFGGTPCPET-VQRKKCRIRKCL RNPSI--QNLRWREARESRRSEQLREESDGDQFPGCRMRPWTAWSECTKLCGGGIQ-ERY MTVKKRFKSSQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >XP_018115643.1 spondin-1 [Xenopus laevis] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MGLIFQPLF------------WQFVATTYA-LMVLG FLDETVEK-AIKSEGYCSRILR----AQGGTRKEGYHEFSLRVEGD-------PDFYKPG NTYR-------------------------------------------------VTLLAAS P----AYFRGFTLIALKEGKEGEKEED----HAGSFQIID-EEDTQFMT---NCPVA-VT ESTPRRRTRIQVFWTAPQIGTGC----VILKASIVQKKIIYFQDEGSLTKRMCEPDLTLE -GGNEKT------MPDCCAC--GTAKYRLTFYGNWSEKTHPKDYPR--RANHWSAIIGGS HSKEYVLWEYGGQASDGVKQVAELGSPVKMEEEIRQKGDEVLTVIKAKAQWPAWQPLNVR AAPSAEFSVDRSRHLMSFLAMMGPSPDWNVGLTSEDLCTKECGWVQKVIQDLIPWDAGTD SGVTYESPNKPTIPQDKIRPLTSL--DHPQSPFYDPEGGPIIPIARVVIERIARK----- -------GEQCNII------PDNVDDIVADLVTEEKDE-D-DTPETCIYSNWSPWSACSS ATCDKGKRMRQRMLKAQ-LDLSVPC--PDTQDFEPCMG--PGC------SDDEA------ ---------------ST-CMMSEWITWSPCSASCGM-GMRSRERYVKQFPEDGSLCKVPT EETEKCI--VNEECEPSS-------CIVTEWAEWEECSATCGMGMK---KRHRMIKMTPA DGSM-C--KADTTEVEKCMMPECHTIP--------CVLSPWS--------------EWSD CSVTCGKGTRTRQRMLKSPAELG-DCNEELKQVEKCMLPE-CP----------------- --ISCELTEWSYWSECNKSCGK--GHMIRTRMITMEPQFGGAVCPET-VQRKKCRLRKCQ KSSGN--ERRHLKDAREKRRSEKIKEDSDGEQYPVCKMKPWTAWTECTKFCGGGIQ-ERF MTVKKRFKSSQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >XP_015808377.1 PREDICTED: spondin-1 isoform X1 [Nothobranchius furzeri] ------------------------------------------------------------ ----MPA----------------------------------------------------- ------------------------SGLDPRVVL------------LLCFISSAA-CNTFA FTEEPSDR-AVKADSYCSRILR----AQ-SNRKEVNNEFRLRVEGD-------PESYQPG STYR-------------------------------------------------VSLTASS P----SYFRGFTLIATREGAEGDRDED----YAGNFQIID-EEETQFMT---NCPPA-VT ESTPRRRTSIQVFWTAPPSGTGC----VLLKASIVQKRIIYFQDEGALTKRMCEKESLYG -DSTDRP------LLDCCAC--GTAKYRVTFYGNWSEKIHPKDYPR--RANHWSALIGAS HSKNYVLWEYGGTASEGVKQVAELGSPVKMEEEIRQKGDDVLTVIKMKAQWPAWQPLNVR AAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWAQKVVQDLIPWDAGTD GGVSYESPNKPTLPQDKIRPLTSL--DHPQSPFYDPEGGAITPVARVMVERIARK----- -------GEQCNIV------PDNVDDIVADIAQEEKEE-D-DTPETCIYSNWSPWSACSS ATCEKGKRMRQRMLKAQ-LDLSVPC--PHTQDFEPCMG--PGC------SDEDA------ ---------------ST-CMMSEWITWSPCSASCGT-GTRSRERYVKQFPDDGSVCTLPT EETENCV--VNEDCLPSS-------CLVTEWAEWDVCSATCGLGMK---RRERMVKMPPA DGSI-C--GAEVLEVEKCMMPECHTIP--------CLLTPWS--------------EWSD CSVTCGKGLRTRQRILKSPAELG-ECTEELEQVEKCMLPE-CP----------------- --IDCSLSEWTEWSECNKSCGK--GHTIRTRIVKLEPQFGGDPCSQT-VQRKKCKVRRCT RGQGNSEEKRRRKEQREKQRGKQGRAEGATEH-PGCRMRPWSSWTECTKLCGGGIQ-ERL MSIKQKFKTVQLSSCKD-RKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >XP_023809284.1 spondin-1 isoform X2 [Oryzias latipes] ------------------------------------------------------------ ----MKA----------------------------------------------------- ------------------------SGLHPAVML------------LLCFISSAA-CTSLG FTEEPFER-AGKADGYCSRILR----AQ-SNRKESNNEFRLRVEGD-------PDSYQPG STYR-------------------------------------------------VNVIASS P----SYFRGFTLIALKEGAGGDKDDD----YAGNFRIID-EDETQFMT---NCPHA-VT ESTPRRRNNIQVFWTAPPTGSGC----VLLKASIVQKKIIFFQDEGPLTKQMCEKESLYG -DATDKP------LLDCCAC--GTAKYRVTFYGNWSEKIHPKDYPR--RANHWSAIIGAS HSKNYVLWEYGGSASDGVKQVAELGSPVKMEEEIRQKGDDVLTVIKMKAQWPAWQPLNVR AAPSAEFSVDRIRHLMSFLTMMGPSPDWNVGLSAENLCTKECGWVQKVVQDLIPWDAGTD SGVSYESSNKPTVPQEKIRPLTSL--DHPQSPFYDPEGGAITPVARVVVERIARK----- -------GEQCNIV------PDNVDDIVADIAQEEKEE-D-DTPETCIYSNWSPWSACSS ATCEKGKRMRQRMLKAQ-LDLSVPC--PHTQDFEPCMG--PGC------SDEDG------ ---------------ST-CMMSEWITWSPCSMSCGA-GIRSRERYVKQFPDDGSICTLPT EETENCV--VNEECSPSS-------CLVTEWGEWDACSATCGLGMK---RRERMVKMPPA DGSI-C--GAEVLEVEKCMMPECHTIP--------CLLTPWS--------------EWSD CSVTCGKGSRTRHRVLKSPLELG-ECTEDLEQVEKCMLPE-CP----------------- --IDCAMSDWTEWSECNKSCGK--GHTIRTRVVTMEPQFGGDPCPET-IQRKKCKVRKCS RGQGNSDDKKRRKEQREKRRSKQVKTEVTSEH-PGCKMRPWSSWTECTKQCGGGIQ-ERL MTVKQKFKTAQLSSCKE-RKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >XP_030271163.1 spondin-1 isoform X2 [Sparus aurata] ------------------------------------------------------------ ----MSV----------------------------------------------------- ------------------------AGRHARVLL------------LLCFVSTAA-CNMFA FTEEPSER-AGKSDGYCSRILR----AQ-SNRKEVNNEFRLRVEGD-------PESYQPG STYR-------------------------------------------------VLLTASS P----SYFRGFTIIAQREGAEGDRDED----YIGNFQIID-EEETQFMT---NCPPA-VT ESTPRRHTSIQVFWTAPRSGSGC----VLLKASIVQKRIIYFQDEGSLTKRMCEKESLYG -DTTEKP------LLDCCAC--GTAKYRVTFYGNWSEKIHPKDYPR--RANHWSAIIGAS HSKSYVLWEYGGLASDGVKQVAELGSPVKMEEEIRQKGDDVLTVIKMKAQWPAWQPLNVR AAPSAEFSVDRTRHIMSFLTMLGPSPDWNVGLSAEDLCTKECGWAQKVVQDLIPWDAGTD SGVTYESPNKPTVPQEKIRPLTSL--DHPQSPFYDPEGGAITPVARVVVERIARK----- -------GEQCNIV------PDNVDDIVADIAQEEKEE-D-DTPETCIYSNWSPWSACSS ATCEKGKRMRQRMLKAQ-LDLSVPC--PHTQDFEPCMG--PGC------SDEDA------ ---------------ST-CMLSEWITWSPCSASCGI-GSRSRERYVKQFPDDGSVCTLPT EETETCV--VNEECSPSS-------CLVTEWGEWDVCSATCGLGMK---RRERLVKMPPT DGSI-C--GAEVLEVEKCMMPECHTIP--------CMLTPWS--------------DWSD CSVTCGKGLRTRQRKLTSPVELG-DCTEELEQVEKCMLPE-CP----------------- --IDCVMSEWTEWSECNKSCGK--GHTIRTRMVKLEPQFGGDSCTET-IQRKKCKIRKCN RGQANSDEKKRRKEQREKRRSKTSRVDATSEH-PGCKMRPWSSWTDCTKLCGGGIQ-ERL MTVKQRFKTAQLSSCKD-RKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >KAB0370901.1 hypothetical protein FD755_017310 [Muntiacus reevesi] ------------------------------------------------------------ ----MVITL--------------------------------------------------- ---------------SKNHA--SGGSVPPYSFQSW------FPGGQTHLSLKSE--LEVS EPSSLLEN-LPKSIDFL-RIVK----KT-GFESEKPTQFLKKTH---------------- ------------------------------------------------------------ -----IYFYSFITLNSIFNYKGNK----------YFEVWT-IPHSGYRSGQ-NALAG-ND LCTPCTKQKV-LRWLHPLVGQGV---GVVLRLQ---------QSKGSLTYRD-------- -------------LRRVCAN---------TDQGYWAQCRHQNSSWR--R----------- HRK---VWSFQGYAA--LRGGAGCAPRNQQWPEMETKNPPSLSPSHPLAIVMVSAFVSRR AAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKLVQDLIPWDAGTD SGVTYESPNKPTIPQEKIRPLTSL--DHPQSPFYDPEGGSITQVARVVIERIARK----- -------GEQCNIV------PDNVDDIVADLAPEEKDE-D-DTPETCIYSNWSPWSACSS STCDKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CTMSEWITWSPCSISCGT-GMRSRERYVKQFPEDGSVCTLPT EETEKCT--VNEECSPSS-------CLTTEWGEWDECSATCGMGMK---KRHRMVKMSPA DGSM-C--KAETSQAEKCMMPECHTIP--------CLLSLWS--------------EWSD CSVTCGKGMRTRQRMLKSLAELG-DCNEELEQVEKCMLPE-CP----------------- --IDCELTEWSQWSECNKSCGK--GHMIRTRMIQMEPQFGGTPCPET-VQRKKCRIRKCL RNPSI--QNLRWREARESRRSEQLREESDGDQFPGCRLRPWTAWSECTKLCGGGIQ-ERY MTVKKRFKSSQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >KAB0347695.1 hypothetical protein FD754_012552 [Muntiacus muntjak] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------MDCSP-------------PGSSVHGILQARILEWVA IPLSRGPS-RPRDQTHISCIGR----QV-LYHCTTWEQFLKKTH---------------- ------------------------------------------------------------ -----IYFYSFITLNSIFNYKGNK----------YFEHI--------------------- -------TQLPYYWVF-RAGIGCPRTSYPLKPTKPTVQVRLQQSKGSLTYAS-RKASLPW -PLFSGPHL----TLQCCST---------------------------------------Q HRK---VWSFQGYT-------ALRGGRNQQWPEMETKNPPSLSPSHPLAIVMVSAFVSRR AAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKLVQDLIPWDAGTD SGVTYESPNKPTIPQEKIRPLTSL--DHPQSPFYDPEGGSITQVARVVIERIARK----- -------GEQCNIV------PDNVDDIVADLAPEEKDE-D-DTPETCIYSNWSPWSACSS STCDKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CTMSEWITWSPCSISCGT-GMRSRERYVKQFPEDGSVCTLPT EETEKCT--VNEECSPSS-------CLTTEWGEWDECSATCGMGMK---KRHRMVKMSPA DGSM-C--KAETSQAEKCMMPECHTIP--------CLLSLWS--------------EWSD CSVTCGKGMRTRQRMLKSLAELG-DCNEELEQVEKCMLPE-CP----------------- --IDCELTEWSQWSECNKSCGK--GHMIRTRMIQMEPQFGGTPCPET-VQRKKCRIRKCL RNPSI--QNLRWREARESRRSEQLREESDGDQFPGCRLRPWTAWSECTKLCGGGIQ-ERY MTVKKRFKSSQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ -------------------------------- >OWK18058.1 SPON1 [Cervus elaphus hippelaphus] ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ------------------------------------------------------------ ---------------------------------------------------MVSTFVSRR AAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKLVQDLIPWDAGTD SGVTYESPNKPTIPQEKIRPLTSL--DHPQSPFYDPEGGSITQVARVVIERIARKEYPTS PRLVGQQGFSCSHVNLSRGRASHSSDRLSGKTPHILFP-D-DTPETCIYSNWSPWSACSS STCDKGKRMRQRMLKAQ-LDLSVPC--PDTQDFQPCMG--PGC------SDEDG------ ---------------ST-CTMSEWITWSPCSISCGT-GMRSRERYVKQFPEDGSVCTLPT EETEKCT--VNEECSPSS-------CLTTEWGEWDECSATCGMGMK---KRHRMVKMSPA DGSM-C--KAETSQAEKCMMPECHTIP--------CLLSLWS--------------EWSD CSVTCGKGMRTRQRMLKSLAELG-DCNEELEQVEKCMLPE-CP----------------- --IDCELTEWSQWSECNKSCGK--GHMIRTRMIQMEPQFGGTPCPET-VQRKKCRIRKCL RNPSI--QNLRWREARESRRSEQLREESDGDQFPGCRMRPWTAWSECTKLCGGGIQ-ERY MTVKKRFKSSQFTSCKD-KKEIRACNV-HPC----------------------------- ------------------------------------------------------------ --------------------------------
BMGE Cleaned alignment of selected proteins >sp|Q9HCB6|SPON1_HUMAN Spondin-1 OS=Homo sapiens OX=9606 GN=SPON1 PE=1 SV=2 MRLSPAPLKLSRTPALLALALPAAALAFSDETLDKVPKSEGYCSRILRGTRREGYTEFSLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALRENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCTMSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLMTEWGEWDECSATCGMGMKKRHRMIKMNPADGSMKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEDLEQVEKCMLPEIDCELTEWSQWSECNKSCGKGHVIRTRMIQMEPQFGGAPCPETVQRKKCRIRKCLRNPSIQKLRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNV >tr|F1R2Z9|F1R2Z9_DANRE F-spondin OS=Danio rerio OX=7955 GN=spon1b PE=4 SV=3 MMDKDGLVV----LLVFLNVFLIHSDAFKRDTAERHSRSEGGFCRILRSARRDGQNEFRLKVEGEPETYQPGSTYRVSLYASSPSYFRGFTLIALKEGREGVSPDDYAGTFKLIDESDTQFMTNCPPAVTESIPRRRTRIQVFWTAPPSGSGCVTLKASVVQRRIIFFQDEGSLTKRLCEKDPVAITEKPAQECCACGTAKYRVTFYGNWSEKLHPKDYPRRANHWSALIGASHTRSYVLWEYGGFASEGVKQVSEYGSPVKMEEEIRQKGDDVMTVIKTKAQWPAWQPLNIRAAPSAEFSVDRVRHLMSFLTMLGPSPDWNVGLSGEDLCTRDCGWVQKLVKDLVPWDAGTDSGVSYESPNKPSIPQERIRPLTSLDHPQSPFYDPSGGPMTPLGRVVVERIARKGEQCNTVPDTIDDIVADIAQEEKEENTPETCIYSNWSPWSACSSSTCDKGRRMRQRMLKAQLDPNLPCLHTQDFEPCMGSEEEACMMSEWISWSPCSASCGMGMRSRERYVKQFPEDGSSCTLPTEETEKCVVNDDCSPSSCVVTEWGEWEPCSVSCGLGMRRRERMMKMDASDGSPRVQMAEAEKCMMPECNAVVCMLSPWSDWGECSVSCGVGMRTRQRMLKTPVKPGQCPDELEQVEKCMLPETDCMLSEWSAWSECNKSCGKGHMIRSRMVKLEPQFGGLPCPETVQRKKCKIRKCSRGSRAEKRKRQEVSDRRRAKQSRESVAEESTVVCPIRPWSSWTECTKPCDGGTQERVMTIKKKGKSSQHNHCKNKKEIRACNV >NP_742064.2 spondin-1 precursor [Rattus norvegicus] MRLSPAPLRLSRGPALLALALPAAALAFSDETLDKVAKSEGYCSRILRGTRREGYTEFSLRVEGDPDFYKPGSSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPTGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDPTGVTDRPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPVNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDTPETCIYSNWSPWSACSSSTCEKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCTMSEWITWSPCSVSCGMGMRSRERYVKQFPEDGSVCMLPTEETEKCTVNEECSPSSCLVTEWGEWDDCSATCGMGMKKRHRMVKMSPADGSMKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEDLEQAEKCMLPEIDCELSEWSQWSECNKSCGKGHMIRTRTIQMEPQFGGAPCPETVQRKKCRARKCLRSPSIQKLRWREARESRRSEQLREESDGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNV >NP_663559.1 spondin-1 precursor [Mus musculus] MRLSPVSLRLSRGPALLALALPAAALAFSDETLDKVTKSEGYCSRILRGTRREGYTEFSLRVEGDPDFYKPGSSYRVTLSAAPPSYFRGFTLIALKENQEGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPTGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDPTGVTDRPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPVNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDTPETCIYSNWSPWSACSSSTCEKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCTMSEWITWSPCSVSCGMGMRSRERYVKQFPEDGSVCMLPTEETEKCTVNEECSPSSCLVTEWGEWDDCSATCGMGMKKRHRMVKMSPADGSMKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEDLEQAEKCMLPEIDCELSEWSQWSECNKSCGKGHMIRTRTIQMEPQFGGVPCPETVQRKKCRTRKCLRSPSVQKLRWREARESRRSEQLREESDGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNV >NP_777168.1 spondin-1 precursor [Bos taurus] MRLSPVLLRLSRGPALLALALPAVALAFSDETLDKVPKSEGYCSRILRGTRREGYTEFSLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCTMSEWITWSPCSISCGTGTRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLTTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMKAETSQAEKCMMPECHTIPCLLSLWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPEIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQFGGTPCPETVQRKKCRIRKCLRNPSIQNLRWREARESRRSEQLREESDGDQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNV >NP_990182.1 spondin-1 precursor [Gallus gallus] MAARLRPL----ALRLLARTFPLVARGFSDETLEKAAKSEGYCSRILRGTRREGYNEFSLRVEGDPEFYKPGNSYRVTLSAATPAYFRGFTLIALKEGKEGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWTAPPTGTGCVILKASIVQKRIIYFQDEGSLTKRICEQDSAGVTDKPTLDCCACGTAKYRLTFYGNWSEKTHPKDFPRRTNHWSAIIGSSHSKNYILWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRHRHLMSFLTMLGPSPDWNVGLSAEDLCTKDCGWVQKVVQDLIPWDAGTDSGVTYESPNKPTVPQEKIRPLTSLDHPQSPFYDPEGGSIKLVARVVLERIARKGEQCNFVPDNIDDIVADLAPEEKEEDTPETCIYSNWSPWSACSSSTCEKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCMMSDWITWSPCSVSCGMGTRSRERYVKQFPEDGSMCKVPTEETEKCIVNEECSPSSCLVTEWGEWDECSASCGTGMKRRHRMIKMTPADGSMKAETTEAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSAAELGDCNEELEQAEKCMLPEIDCELTEWSQWSECNTSCGKGHMIRTRMIKIEPQFGGTACPETVQRTKCRVRKCLRGPGMEKRRWKEAREKRRSEQAKKNIDNEQYPVCRLKPWTAWTECSTLCGGGIQERYMMVKKRSKSTQFTSCKDKKELRACNV >XP_508295.3 spondin-1 [Pan troglodytes] MRLSPAPLKLSRTPALLALALPAAALAFSDETLDKVPKSEGYCSRILRGTRREGYTEFSLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCTMSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLMTEWGEWDECSATCGMGMKKRHRMIKMSPADGSMKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEDLEQVEKCMLPEIDCELTEWSQWSECNKSCGKGHVIRTRMIQMEPQFGGAPCPETVQRKKCRIRKCLRNPSIQKLRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNV >XP_534067.2 spondin-1 [Canis lupus familiaris] MRLSPAPPGLSPSPALLALALPAAALAFSDETLDKVPKSEGYCSRILRGTRREGYTEFSLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSMGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCTMSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLMTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPEIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQFGGAPCPETVQRKKCRIRKCLKNPSIQKLRWREARESRRGEQLREESDGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNV >XP_002708869.1 PREDICTED: spondin-1 [Oryctolagus cuniculus] MRLSPAPLRLSRTLALLALALPAAALAFSDETLDKVAKSEGYCSRILRGTRREGYTEFSLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPTGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSIIQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCTMSEWITWSPCSISCGTGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLMTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMKAETSQTEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPEIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQFGGAPCPETVQRKKCRVRKCLRNPSIQKLRWREARESRRGEQLREESDGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNV >XP_002822053.2 spondin-1 [Pongo abelii] MRLSPATLKLSRTPALLALALPAAALAFSDETLDKVPKSEGYCSRILRGTRREGYTEFSLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCTMSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLMTEWGEWDECSATCGMGMKKRHRMIKMSPADGSMKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEDLEQVEKCMLPEIDCELTEWSQWSECNKSCGKGHVIRTRMIQMEPQFGGAPCPETVQRKKCRIRKCLRNPSIQKLRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNV >XP_003123014.4 spondin-1 [Sus scrofa] MRLSPASVKLSGSPALLALALPAAALAFSDETLDKVPKSEGYCSRILRGTRREGYTEFSLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKVCEQDSTGVTDRPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCTMSEWITWSPCSISCGTGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLMTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPEIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQFGGAPCPETVQRKKCRIRKCLRNPSIQKLRWREARESRRSEQLREESDGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNV >XP_031409214.1 spondin-1 [Meleagris gallopavo] ------------------------------MCFTSSAKDAAFPHPI----ATDDVNTWCV----------------VTLSAATPAYFRGFTLIALKEGKEGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWTAPPTGTGCVILKASIVQKRIIYFQDEGSLTKRICEQDSAGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDFPRRTNHWSAIIGSSHSKNYILWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRHRHLMSFLTMLGPSPDWNVGLSAEDLCTKDCGWVQKVVQDLIPWDAGTDSGVTYESPNKPTVPQEKIRPLTSLDHPQSPFYDPEGGSIKLVARVVIERIARKGEQCNIVPDNIDDIVADLAPEEKEEDTPETCIYSNWSPWSACSSSTCEKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCMMSDWITWSPCSVSCGMGTRSRERYVKQFPEDGSMCKVPTEETEKCIVNEECSPSSCLVTEWGEWDECSASCGTGMKRRHRMIKMTPADGSMKAETTEAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSAAELGDCNEELEQAEKCMLPEIDCELTEWSQWSECNTSCGKGHMIRTRMIKIEPQFGGTACPETVQRTKCRVRKCLRGPGMEKRRWKEAREKRRSEQAKKNIDNEQYPVCRLKPWTAWTECSTLCGGGIQERYMMVKKRSKSTQFTSCKDKKELRACNV >XP_034788091.1 spondin-1 [Pan paniscus] MRLSPAPLKLSRTPALLALALPAAALAFSDETLDKVPKSEGYCSRILRGTRREGYTEFSLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCTMSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLMTEWGEWDECSATCGMGMKKRHRMIKMSPADGSMKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEDLEQVEKCMLPEIDCELTEWSQWSECNKSCGKGHVIRTRMIQMEPQFGGAPCPETVQRKKCRIRKCLRNPSIQKLRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNV >XP_023095364.1 spondin-1 [Felis catus] MRLSPAPLRLSRSPALLALALPAAALAFSDETLDKVPKSEGYCSRILRGTRREGYTEFSLRVEGDPDFYKPGISYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSMGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCTMSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLMTEWGEWDDCSATCGMGMKKRHRMVKMSPADGSAKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPEIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQFGGAPCPETVQRKKCRIRKCLRNPSIQKLRWREARESRRNEQLREESGGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNV >XP_027835169.1 spondin-1 [Ovis aries] MRLSPVLLRLSRGPALLALALPAVALAFSDETLDKVPKSEGYCSRILRGTRREGYTEFSLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCTMSEWITWSPCSISCGAGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLTTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMKAETSQAEKCMMPECHTIPCLLSLWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPEIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQFGGAPCPETVQRKKCRIRKCLRNPSLQNLRWREARESRRSEQLREESDGDQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNV >XP_018893034.2 spondin-1 [Gorilla gorilla gorilla] MRLSPASLKLSRTPALLALALPAAALAFSDETLDKVPKSEGYCSRILRGTRREGYTEFSLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCTMSEWITWSPCSISCGMGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLMTEWGEWDECSATCGMGMKKRHRMIKMSPADGSMKAETSQAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEDLEQMEKCMLPEIDCELTEWSQWSECNKSCGKGHVIRTRMIQMEPQFGGAPCPETVQRKKCRIRKCLRNPSIQKLRWREARESRRSEQLKEESEGEQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNV >XP_005499371.1 spondin-1 isoform X1 [Columba livia] MGAHLQPL----ALRLLALTFPLVAKGFSDETLEKAAKSEGYCSRILRGTRREGYNEFSLRVEGDPEFYKPGNSYRVTLSAATPAYFRGFTLIALKEGKEGDKEEDHAGAFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWTAPPTGTGCVILKASIVQKRIIYFQDEGSLTKKICEQDSAGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDFPRRTNHWSAIIGSSHSKNYILWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRHRHLMSFLTMLGPSPDWNVGLSAEDLCTKDCGWVQRVVQDLIPWDAGTDSGVTYESPNKPTVPQEKIRPLTSLDHPQSPFYDPEGGSIKLVARVVIERIARKGEQCNIVPDNIDDIVADLAPEEKEEDTPETCIYSNWSPWSACSSSTCEKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCMMSDWITWSPCSVSCGMGTRSRERYVKQFPEDGSMCKVPTEETEKCVVNEECSPSSCLVTEWGEWDECSASCGMGMKRRHRMIKMTPADGSMKAETTEAEKCMMPECHTIPCLLSPWSEWSDCSVTCGKGMRTRQRILKSAAELGDCNEELEQAEKCMLPEIDCELTEWSQWSECNTSCGKGHMIRTRMIKIEPQFGGTACPETVQRTKCRLRKCLRGPGMEKRRWKEAREKRRSEQAKKNIDSEQYPVCRLKPWTAWTECSTFCGGGIQERYMMVKKRSKSTQFTSCKDKKELRACNV >XP_017915073.1 PREDICTED: spondin-1 [Capra hircus] MRLSPVLLRLSRGPALLALALPAVALAFSDETLDKVPKSEGYCSRILRGTRREGYTEFSLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALKENRDGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKVVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCTMSEWITWSPCSISCGAGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLTTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMKAETSQAEKCMMPECHTIPCLLSLWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPEIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQFGGAPCPETVQRKKCRIRKCLRNPSLQNLRWREARESRRSEQLREESDGDQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNV >XP_006028011.1 spondin-1 [Alligator sinensis] MGLHPQALL---AWPLLALAFPSVALGFSDETLEKATKSEGYCSRILRGTRREGYNEFSLRVEGDPEFYKPGNSYRVTLSAATPAYFRGFTLIALKEGKEGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWTAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSAGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDFPRRTNHWSAIIGSSHSKNYILWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPVNVRAAPSAEFSVDRHRHLMSFLTMLGPSPDWNVGLSAEDLCTKDCGWVQKVVQDLIPWDAGTDSGVTYESPNKPTVPQEKIRPLTSLDHPQSPFYDPEGGSIKLVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKEEDTPETCIYSNWSPWSACSSSTCEKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCMMSEWITWSPCSVSCGMGTRSRERYVKQFPEDGSMCKVPTEETEKCIVNEECAPSSCLVTEWGEWDECSASCGMGMKKRYRMIKMTPADGSMKTETTEAEKCMMPECHTIPCMLSPWSEWSDCSVTCGKGMRTRQRMLKSAAELGDCNEELEQVEKCMLPEIDCELTEWSHWSECNKSCGKGHMIRTRMIKMEPQFGGAPCPETVQRKKCRIRKCLRNPSIEKRRWKEAREKRRSEQAKKDIDSEQYPGCKMRPWTAWSECTKLCGGGIQERFMIVKKRFKNTQFTSCKDKKEIRACNV >XP_014457833.1 PREDICTED: spondin-1 [Alligator mississippiensis] MGLHPQALL---AWPLLALAFPSVALGFLDETLEKATKSEGYCSRILRGTRREGYNEFSLRVEGDPEFYKPGNSYRVTLSAATPAYFRGFTLIALKEGKEGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWTAPPAGTRCVILKASIVQKRIIYFQDEGSLTKKLCEQDSAGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDFPRRTNHWSAIIGSSHSKNYILWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPVNVRAAPSAEFSVDRHRHLMSFLTMLGPSPDWNVGLSAEDLCTKDCGWVQKVVQDLIPWDAGTDSGVTYESPNKPTVPQEKIRPLTSLDHPQSPFYDPEGGSIKLVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKEEDTPETCIYSNWSPWSACSSSTCEKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCMMSEWITWSPCSVSCGMGTRSRERYVKQFPEDGSMCKVPTEETEKCIVNEECAPSSCLVTEWGEWDECSASCGMGMKKRYRMIKMTPADGSMKTETTEAEKCMMPECHTIPCMLSPWSEWSDCSVTCGKGMRTRQRMLKSAAELGDCNEELEQVEKCMLPEIDCELTEWSHWSECNKSCGKGHMIRTRMIKMEPQFGGAPCPETVQRKKCRIRKCLRNPSIEKRRWKEAREKRRSEQAKKDIDSEQYPGCKMRPWTAWSECTKLCGGGIQERFMIVKKRFKNTQFTSCKDKKEIRACNV >XP_020728710.1 spondin-1 [Odocoileus virginianus texanus] MRLSPVLLRLSRGPALLALALPAVALAFSDETLDKVPKSEGYCSRILRGTRREGYTEFRLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKLVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCTMSEWITWSPCSISCGTGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLTTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMKAETSQAEKCMMPECHTIPCLLSLWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPEIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQFGGAPCPETVQRKKCRIRKCLRNPSIQNLRWREARESRRSEQLREESDGDQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNV >XP_040184219.1 LOW QUALITY PROTEIN: spondin-1 [Rana temporaria] MGLLVQALY----LSYVAVTCLSVVSGFTDETVEKAVKSEGYCSRILRSTRKEGYHEFSLRVEGDPEYYKPGSTYRVTLSATTPAYFRGFTLIALKEGKEGEKEEDHAGSFQIIDDEETQFMSNCPVAVTESTPRRRTRIQVLWTAPSIGTGCVILKASIVQKKIIYFQDEGSLTKRMCELDVTGANEKTIPDCCACGTAKYRLTFYGNWSEKAHAKDYPRRANHWSAIIGGSHSKSYVLWEYGGYASDGVKQVAELGSPVKMEEEIRQKGDDVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLAMLGPSPDWNVGLSAEDLCTKECGWVQRVVQDLIPWDAGTDSGVSYESPNKPTIPQDKIRPLTSLDHPQSPFYDPEGGPIVPVARVVIERIARKGEQCNIVPDNVDDIVADLVAEEKERDTPETCLSSNWSPWSACSSAHVRKGKRMRQAMLKAQLDLSVXLPDTQDFEPCMGSVDDACMMSEWIMWSPCSASCGXGMRSRERYVKLFPEDGSLCKVPTEETEKCIVNEECEPSSCIVTEWGEWEECSATCGMGMKKRHRMIKMTPADGSMKTETSEVEKCMMPECHTIPCVLSPWSDWSDCSVTCGKGSRTRQRMLKSPAELGDCNEELKQVEKCMLPEINCELTEWSHWSECNKSCGKGHMIRTRMITLEPQFGGGNCPETVQRKKCRVRKCQKNSGGEKRRLKDAREKRRSERTNEEVDGEHSPVCKMKPWTTWTECSKYCGGGIQERFMTVKKRFKSSQFTSCKDKKEIRACNV >XP_039254629.1 spondin-1-like [Styela clava] MNTSPKACLSQMKSFCFLMQIMCVVISFRPSHSQEFPIDFTNCDFNTEVLPRSGDNGFSVKIEGMPEYYESEKSYTVTISSTHPATFRGFALAAVH----ANNYSLPAGNFKLLNPSSTKKHPSCSNIVTQTTLGKKASVQFVWDSPAPGFGCVQFKAVIIQKGKIWYRNEDKLTQTLCETIDSARV---AHICCSCGSAQYRMTFYGLWSPQTHPKDYPGYSTHWSNVIGASHNDRYTIWDYGQYATDGVKKVAEWGWPNAVENEIRAQGDSVISVIKTRAQWPAFQPRNIREPPSAMFDVDASRHLVSLLTMLGPSPDWNVGITKESMCTSQCGWINTKSYDLTPWDAGTDSGVSYLSPNSPTNPQDRIRALTSSDDTESPFYDPLGRPIEPVARVVLERISISGDQCGPSNSAPRSTGIDILSSPSVIPPLTSCLYGEWSEWSQC-GVTCGWGIKMRTKSLINKLLPSASCPSITEKEICKGDNEDDCLYSEWTKWSDCTAPCGSALRFRTREL-QWPSEPKNCHEPLKEMRFDCNTEPCELDVCEYGTWSDWMPCSTQCGIGQTLRKK---FSIQSTEKESPVMEISKCMASTDCAAPCSYSPWTGWMPCPVTCGVGETFRKRVLDFSTPDIHCDEFQMERTKCMTSEQHCEYSEWSEWMPCSASCDVGNTLRKRFLKKT--NTVANCEELMETVQCYMPPCSVMIPK-----------------EDSLPHATQKSCIYGEWTAWMPCSVTCGRGETLRKRFLKKSLDISQ--TCDGEMETNRCTV >XP_038071797.1 spondin-1-like [Patiria miniata] MAR----IF--TKMFTILSFYSLTLLAGT------LGASRRACSRLPGVPKRPGDNGYRIRISGHPSFYVPGQEYLVTLSSTPPVSFREFTFACLL----VEDDATSAGHFEIVDDRLAQFSPNCPELLIHTSKASKTSVTFRWIAPPAGTGCVNFKAAAVQKKQIWYKDERGLTLWLCEEDVAVPPQTNNIECCACHTAKYTVTMRGLWSQETHPKDFPGHGDHWSDLIGASHTKDYTIWKYGGYASLGVQRVAEWGSPTTLEREILAQTRNIKTVIRSRGLWPA------RGNMSAVLSVNRTHNLVSTLSMIGPSPDWCVGVSRVNLCTADCDWLQRLEIDLLPWDAGTDSGITFRSDNAPTVPIEPIHPITSSSNPLGAFYDPMGRPIPPMAILVFERTDNT-------YDDLGEVVCEVDVGGPDA------------------THTGGGGMPPKEGMMPPKEGMMPPKTMMPPKEGMMP-----------------------GTMMPPKEGMMPPKEGMIPSPD---------GEIMPPKPGMMNKGGELSNVTTPMMKKP-VPEGDITMPPKVMPN---EGEDIPVTMPPKHAKTCMMSPWSDWTECSRSCGKGTMRRQRMVKQKARHGQACGKQKEKKNCSTGPRDCMMSDWGEWTPCSVTCGNGTQIRMRKIKKKARGSGQPCGPRREERVCGTP-------------------------------------------------------------------------------------- >XP_003251296.1 spondin-1 [Apis mellifera] -------------------MLLLTVTACL------VITVQAGCPMRPTASRTTGDGGYRILVSGKADKYIPNAVYTISLQGSQTQQFTHFTLSVNSQH-APSNPTARVGYFQLFPDGLTTFNEDCVNTISEASDYPKNEVQVMWRAPPSGSGCVIFTAMVLENNVRWYAEDGALTKTFCEMDSSEALD--GEKCCACDEAKYSLIMEGIWSNVTHPKDFPFWLTHFSDLIGASHVPSFSFWGKDHVATDGFRQLAEWGSASGVETELRANSNKLRTLIKAAGLWYP----NVNSNTTTNFRVDRKRPMISVASMFGPSPDWVVGVSKLNLCRKDCSWTKSEIIDLYPWDAGTDNGISYMSPNSETTPREKMKPITTLEDPRSPFYDPSGRPMLPLARLYLTREKIIPRGCD--EEVLQQQVAQLEVAENTETVRPECQTTEYTGWSSC-SVSCGKGLRMRTRSYLMPKAAMFKCRQLVSKEMCVSSGEEDCETTDWGHWSECSSSCGVGIKMRTRRFKDRMGRKRCPHVYLVEKVKCM-EPACSPGLCKVTDWSDWSPCSASCGKGVKLRTRLLMVDPSKQQERMELVQQRPCLDQADCTFDCMEEPNAQKLMCVPFVYGGCRGNRNNFLTAEECNNTCGI----VRAILSGVHCVVSGWSPWTPCSVSCGTGRVTSFRTIQQEARNGGNPCPKKQRRSRCQLAPCE----------------------------------------------------------------------------------- >XP_030844169.1 spondin-1 [Strongylocentrotus purpuratus] MGA--KKLF----LGTFLLFVTIWIVSGQ---------EEESCDPVMVIPKRNGDNGYRIRVDRLPTDYVPGQEYRVLLQSTTPVSFREFFLVATK----GSAPNEAAGDFVITDRLKVRFSRTCSRALTHTFSSSKTSISAQWLAPPAGAGCVNFRAGVIQKKTVWFAEDGDLTLQLCERESAGPAPPPPHACCAPEEAKYRFTFVSTWTPQTHPRQYPTNGNHWSDLIGASHGSDYTIWEYGQYASYGIKMVAEWGSPYRLEREIKEEGDNVKTVIFSRGLFPAYGP-RLR-NMTSYFKTDSQRNLVSAVSMMGPSPDWCVGISKENLCTADCGWVERKVFYLQPWDAGTDSGIMYNSSNSPLDPPDPIRPITSSDNPRASFYNPNGGPIGSLATVVIERVSIR----------------NRSNTETEHTGSQGGVHGGMPPKKPM-----MGGNPTMPPKVMGQPDPTMPPKVMGGHDPTMP--------------------------MGGHDLTMPPKVMGRP------------DPTMPPKV---MRGRDPTMPSKVMAQEPTKQMGVITMPPKTIEI---IPEGDIQTMPPKRRGKCMMTAWGEWSECSKSCGKGKMLRQRMIKQRPRNGEECGQTKERQSCNVARRDCRMSEWGPWSDCSVSCGGGIEFRMRDVARRARGDGAPCDPLKEMRACSANPC------------------------------------------------------------------------------------ >NP_477435.1 fat-spondin [Drosophila melanogaster] MGQ------------SLPLLIRLIVVIWL------TISMVTACPRAPTGRRTRGDNGYKLIVADGPNGYVPGKTYNLLLLGSRTQHFTHFTITAEAHT-GARRPQARVGRFQLFSDSLTQFNDRCVNTVSEADDLPKTEVQVMWVAPESGSGCVSLSAMVYEGPRAWFADDGNLSTVICERKPDAA----QKECCACDEAKYSFVFEGIWSNETHPKDYPFWLTHFSDVIGASHESNFSFWGENHIATAGFRSLAEWGSPAALETELRANGPKLRTLIKAAGLWYP----NVNQNTSSKFRVDRKHPKVSLVSMFGPSPDWVVGISGLDLCTEDCSWKESMDFDLFPWDAGTDSGISYMSPNSETQPPERMYRITTMEDPRAPFYNPKSREMTPLAKLYLRREKIVSRNCD--DEFL--QALQLEVSDDAEDTRAECRVGDYSAWSPC-SVSCGKGIRMRSRQYLYPAADQNKCRQLVAKEMCVASKDRDCKTSPWSVWSECSASCGIGITMRTRTFVNHLGRKRCPHITIVEKNKCM-RPDCTYEQCPTSQWSDWSPCSSTCGRGVTIRTRLLLLENGPDKERMELHQQKECVNPIDCHINCVQAPDPQNQHCYSFTYGGCRGNRNNFLTENDCLNTCNV----LRSPYS-RACVLSDWSVWSPCSVSCGVGVSESRRYVVTEPQNGGQPCSKRVKSRSCAMPAC------------------------------------------------------------------------------------ >NP_495473.2 F-spondin [Caenorhabditis elegans] MLR----------FVAILQFILLLLLIFS------CNADEAKCTIKPYGDKSPGSNGYVIEINGTSKGFVPGEIYKVSIRGWRTKTFRGFVVSSLFE------DNTSAGSWQVVKHGDARISPGCRQSVSHANLKSKTSVHMMWKAPEVSSGCVVFRASVIETKYIWFTEAEGLTVKLCIQKGTKPVDDPSATCCACDIAQYDLEFTGIWSKNTHPKDYPTHLTHFTDMLGSSHSSNYSLWTIGGISTDGMKEIAEWGNTYKAEAEAKAKASEVRSLMKVKGLWFP----DVQGTTKSQFVVNKYHHFVSLATMFGPSPDWCVGLSSVNLCLPDCTWAEERTFELQPFDAGTDSGPTYMSPNEPTEPREPIHWITTKLNPLSPFYNSKSDTIPTLAKVILRRKNVTSSECKS-DDILKAEAHNITNTSEDEKDRRECMMTQWEPWSLC-SATCGKGIRIRSRVYVFPKAQVFHCRQTTEKQFCNAENSEACQVSSWGSWGECSVQCGHGMRSRNRTFLNPATKSGDCSVDLERKDICVNGDDCNVTPCKTTAWSDWSPCSASCDEGVRVRTRLFFYSEHEKR-HVNLQEKDTCVMQSCRRFICQEDKQAEKTQCERFIFTGCKGNRNQFETEEECKQICLPGYEKSKSLIPNVDCEVSKWTAWGSCSVSCGRGKKSRSRHVVKLARNGGHQCSEHMQELQCRLRPCPVKL-----------------------------TCQVGPWSRWSPCSVSCGEGSQRRRRVVRARNDDWEEIECDDETEVRQCTG >XP_031569176.1 spondin-2-like isoform X1 [Actinia tenebrosa] MFL-------------------------------------------------------------------------------------------------------ARASFIISL--------NIILAVAESTIENQTC---------SGEDC-----------------------KLNSRTEVTPPQPVDLKCCACGQATYRMTFVGKWSRLTHPRHFPGPMSSWSALIGCSHSNEYHMWRYGNLASLGVQRLGEWGSTSKLEEEMRKQGNKVLNIIKMPGLWWG------VGRSVIEFRADQTHSLLSVMSRIVPSPDWYVGVDSLNLCHVNCTWKNEETVDLFPLDAGTDDGINFISVNARSNPQQPIRRIDTRNHPMSSFYLPDNDAIRPFAQIKIERLGVSGSCLRS------------NMKGPFPPARIDCQVSRWSSWTPC-SVTCGLGKQVRGRDVIVQMHDGIPCPNLYDYKICDLDDNNNCLVSAWSTWSKCTGTCGIGFKVRKRTIIRQPALGN---------------------------------------------------------------------------------------------------------------KTCPKLIKKRRCRLSPADCVVSAWSSWSECNRQCNRGKKKRTRQILNKAKDGGRRCPRLQEKRKCLVRKCPKK--------------------------------------------------------------------------------- >XP_043337550.1 spondin-1 [Cervus canadensis] MRLSPVLLRLSRGPALLALALPAVALAFSDETLDKVPKSEGYCSRILRGTRREGYTEFRLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKLVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCTMSEWITWSPCSISCGTGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLTTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMKAETSQAEKCMMPECHTIPCLLSLWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPEIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQFGGTPCPETVQRKKCRIRKCLRNPSIQNLRWREARESRRSEQLREESDGDQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNV >KAF4009007.1 hypothetical protein G4228_000364 [Cervus hanglu yarkandensis] MRLSPVLLRLSRGPALLALALPAVALAFSDETLDKVPKSEGYCSRILRGTRREGYTEFRLRVEGDPDFYKPGTSYRVTLSAAPPSYFRGFTLIALKENREGDKEEDHAGTFQIIDEEETQFMSNCPVAVTESTPRRRTRIQVFWIAPPAGTGCVILKASIVQKRIIYFQDEGSLTKKLCEQDSTGVTDKPILDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKNYVLWEYGGYASEGVKQVAELGSPVKMEEEIRQQSDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKLVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCTMSEWITWSPCSISCGTGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLTTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMKAETSQAEKCMMPECHTIPCLLSLWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPEIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQFGGTPCPETVQRKKCRIRKCLRNPSIQNLRWREARESRRSEQLREESDGDQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNV >XP_018115643.1 spondin-1 [Xenopus laevis] MGLIFQPLF----WQFVATTYALMVLGFLDETVEKAIKSEGYCSRILRGTRKEGYHEFSLRVEGDPDFYKPGNTYRVTLLAASPAYFRGFTLIALKEGKEGEKEEDHAGSFQIIDEEDTQFMTNCPVAVTESTPRRRTRIQVFWTAPQIGTGCVILKASIVQKKIIYFQDEGSLTKRMCEPDLTGGNEKTMPDCCACGTAKYRLTFYGNWSEKTHPKDYPRRANHWSAIIGGSHSKEYVLWEYGGQASDGVKQVAELGSPVKMEEEIRQKGDEVLTVIKAKAQWPAWQPLNVRAAPSAEFSVDRSRHLMSFLAMMGPSPDWNVGLTSEDLCTKECGWVQKVIQDLIPWDAGTDSGVTYESPNKPTIPQDKIRPLTSLDHPQSPFYDPEGGPIIPIARVVIERIARKGEQCNIIPDNVDDIVADLVTEEKDEDTPETCIYSNWSPWSACSSATCDKGKRMRQRMLKAQLDLSVPCPDTQDFEPCMGSDDEACMMSEWITWSPCSASCGMGMRSRERYVKQFPEDGSLCKVPTEETEKCIVNEECEPSSCIVTEWAEWEECSATCGMGMKKRHRMIKMTPADGSMKADTTEVEKCMMPECHTIPCVLSPWSEWSDCSVTCGKGTRTRQRMLKSPAELGDCNEELKQVEKCMLPEISCELTEWSYWSECNKSCGKGHMIRTRMITMEPQFGGAVCPETVQRKKCRLRKCQKSSGNERRHLKDAREKRRSEKIKEDSDGEQYPVCKMKPWTAWTECTKFCGGGIQERFMTVKKRFKSSQFTSCKDKKEIRACNV >XP_015808377.1 PREDICTED: spondin-1 isoform X1 [Nothobranchius furzeri] SGLDPRVVL----LLCFISSAACNTFAFTEEPSDRAVKADSYCSRILRSNRKEVNNEFRLRVEGDPESYQPGSTYRVSLTASSPSYFRGFTLIATREGAEGDRDEDYAGNFQIIDEEETQFMTNCPPAVTESTPRRRTSIQVFWTAPPSGTGCVLLKASIVQKRIIYFQDEGALTKRMCEKESLDSTDRPLLDCCACGTAKYRVTFYGNWSEKIHPKDYPRRANHWSALIGASHSKNYVLWEYGGTASEGVKQVAELGSPVKMEEEIRQKGDDVLTVIKMKAQWPAWQPLNVRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWAQKVVQDLIPWDAGTDGGVSYESPNKPTLPQDKIRPLTSLDHPQSPFYDPEGGAITPVARVMVERIARKGEQCNIVPDNVDDIVADIAQEEKEEDTPETCIYSNWSPWSACSSATCEKGKRMRQRMLKAQLDLSVPCPHTQDFEPCMGSDEDACMMSEWITWSPCSASCGTGTRSRERYVKQFPDDGSVCTLPTEETENCVVNEDCLPSSCLVTEWAEWDVCSATCGLGMKRRERMVKMPPADGSIGAEVLEVEKCMMPECHTIPCLLTPWSEWSDCSVTCGKGLRTRQRILKSPAELGECTEELEQVEKCMLPEIDCSLSEWTEWSECNKSCGKGHTIRTRIVKLEPQFGGDPCSQTVQRKKCKVRRCTRGQGNEKRRRKEQREKQRGKQGRAEGATEH-PGCRMRPWSSWTECTKLCGGGIQERLMSIKQKFKTVQLSSCKDRKEIRACNV >XP_023809284.1 spondin-1 isoform X2 [Oryzias latipes] SGLHPAVML----LLCFISSAACTSLGFTEEPFERAGKADGYCSRILRSNRKESNNEFRLRVEGDPDSYQPGSTYRVNVIASSPSYFRGFTLIALKEGAGGDKDDDYAGNFRIIDEDETQFMTNCPHAVTESTPRRRNNIQVFWTAPPTGSGCVLLKASIVQKKIIFFQDEGPLTKQMCEKESLDATDKPLLDCCACGTAKYRVTFYGNWSEKIHPKDYPRRANHWSAIIGASHSKNYVLWEYGGSASDGVKQVAELGSPVKMEEEIRQKGDDVLTVIKMKAQWPAWQPLNVRAAPSAEFSVDRIRHLMSFLTMMGPSPDWNVGLSAENLCTKECGWVQKVVQDLIPWDAGTDSGVSYESSNKPTVPQEKIRPLTSLDHPQSPFYDPEGGAITPVARVVVERIARKGEQCNIVPDNVDDIVADIAQEEKEEDTPETCIYSNWSPWSACSSATCEKGKRMRQRMLKAQLDLSVPCPHTQDFEPCMGSDEDGCMMSEWITWSPCSMSCGAGIRSRERYVKQFPDDGSICTLPTEETENCVVNEECSPSSCLVTEWGEWDACSATCGLGMKRRERMVKMPPADGSIGAEVLEVEKCMMPECHTIPCLLTPWSEWSDCSVTCGKGSRTRHRVLKSPLELGECTEDLEQVEKCMLPEIDCAMSDWTEWSECNKSCGKGHTIRTRVVTMEPQFGGDPCPETIQRKKCKVRKCSRGQGNDKKRRKEQREKRRSKQVKTEVTSEH-PGCKMRPWSSWTECTKQCGGGIQERLMTVKQKFKTAQLSSCKERKEIRACNV >XP_030271163.1 spondin-1 isoform X2 [Sparus aurata] AGRHARVLL----LLCFVSTAACNMFAFTEEPSERAGKSDGYCSRILRSNRKEVNNEFRLRVEGDPESYQPGSTYRVLLTASSPSYFRGFTIIAQREGAEGDRDEDYIGNFQIIDEEETQFMTNCPPAVTESTPRRHTSIQVFWTAPRSGSGCVLLKASIVQKRIIYFQDEGSLTKRMCEKESLDTTEKPLLDCCACGTAKYRVTFYGNWSEKIHPKDYPRRANHWSAIIGASHSKSYVLWEYGGLASDGVKQVAELGSPVKMEEEIRQKGDDVLTVIKMKAQWPAWQPLNVRAAPSAEFSVDRTRHIMSFLTMLGPSPDWNVGLSAEDLCTKECGWAQKVVQDLIPWDAGTDSGVTYESPNKPTVPQEKIRPLTSLDHPQSPFYDPEGGAITPVARVVVERIARKGEQCNIVPDNVDDIVADIAQEEKEEDTPETCIYSNWSPWSACSSATCEKGKRMRQRMLKAQLDLSVPCPHTQDFEPCMGSDEDACMLSEWITWSPCSASCGIGSRSRERYVKQFPDDGSVCTLPTEETETCVVNEECSPSSCLVTEWGEWDVCSATCGLGMKRRERLVKMPPTDGSIGAEVLEVEKCMMPECHTIPCMLTPWSDWSDCSVTCGKGLRTRQRKLTSPVELGDCTEELEQVEKCMLPEIDCVMSEWTEWSECNKSCGKGHTIRTRMVKLEPQFGGDSCTETIQRKKCKIRKCNRGQANEKKRRKEQREKRRSKTSRVDATSEH-PGCKMRPWSSWTDCTKLCGGGIQERLMTVKQRFKTAQLSSCKDRKEIRACNV >KAB0370901.1 hypothetical protein FD755_017310 [Muntiacus reevesi] GSVPPYSFQFPGGQTHLSLKSE-LEVSEPSSLLENLPKSIDFL-RIVKGFESEKPTQFLKKTH---------------------IYFYSFITLNSIFNYKGNK------YFEVWTIPHSGYRSNALAGNDLCTPCTKQKV-LRWLHPLVGQGVVVLRLQ---------QSKGSLTYRD------------LRRVCAN-------TDQGYWAQCRHQNSSWRR-----------HRK---VWSFQGYAA--LRGGAGCAPRNQQWPEMETKNPPSLSPSHPLAIVMVSAFVSRRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKLVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCTMSEWITWSPCSISCGTGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLTTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMKAETSQAEKCMMPECHTIPCLLSLWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPEIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQFGGTPCPETVQRKKCRIRKCLRNPSIQNLRWREARESRRSEQLREESDGDQFPGCRLRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNV >KAB0347695.1 hypothetical protein FD754_012552 [Muntiacus muntjak] MDCSP-----PGSSVHGILQARLEWVAIPLSRGPSRPRDQTHISCIGRLYHCTTWEQFLKKTH---------------------IYFYSFITLNSIFNYKGNK------YFEHI-----------------------TQLPYYWVF-RAGIGCYPLKPTKPTVQVRLQQSKGSLTYAS-RKASLPLFSGPTLQCCST-----------------------------------QHRK---VWSFQGYT-------ALRGGRNQQWPEMETKNPPSLSPSHPLAIVMVSAFVSRRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKLVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGEQCNIVPDNVDDIVADLAPEEKDEDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCTMSEWITWSPCSISCGTGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLTTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMKAETSQAEKCMMPECHTIPCLLSLWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPEIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQFGGTPCPETVQRKKCRIRKCLRNPSIQNLRWREARESRRSEQLREESDGDQFPGCRLRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNV >OWK18058.1 SPON1 [Cervus elaphus hippelaphus] --------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MVSTFVSRRAAPSAEFSVDRTRHLMSFLTMMGPSPDWNVGLSAEDLCTKECGWVQKLVQDLIPWDAGTDSGVTYESPNKPTIPQEKIRPLTSLDHPQSPFYDPEGGSITQVARVVIERIARKGFSCSHVASHSSDRLSGKTPHILFPDTPETCIYSNWSPWSACSSSTCDKGKRMRQRMLKAQLDLSVPCPDTQDFQPCMGSDEDGCTMSEWITWSPCSISCGTGMRSRERYVKQFPEDGSVCTLPTEETEKCTVNEECSPSSCLTTEWGEWDECSATCGMGMKKRHRMVKMSPADGSMKAETSQAEKCMMPECHTIPCLLSLWSEWSDCSVTCGKGMRTRQRMLKSLAELGDCNEELEQVEKCMLPEIDCELTEWSQWSECNKSCGKGHMIRTRMIQMEPQFGGTPCPETVQRKKCRIRKCLRNPSIQNLRWREARESRRSEQLREESDGDQFPGCRMRPWTAWSECTKLCGGGIQERYMTVKKRFKSSQFTSCKDKKEIRACNV
PhyML tree of selected proteins (KAB0370901_1_hypothetical_protein_FD755_017310__Muntiacus_reevesi_:0.07910587,KAB0347695_1_hypothetical_protein_FD754_012552__Muntiacus_muntjak_:0.08464406,(OWK18058_1_SPON1__Cervus_elaphus_hippelaphus_:0.05206769,((XP_043337550_1_spondin_1__Cervus_canadensis_:0.00000001,KAF4009007_1_hypothetical_protein_G4228_000364__Cervus_hanglu_yarkandensis_:0.00000001):0.00000001,(XP_020728710_1_spondin_1__Odocoileus_virginianus_texanus_:0.00000001,(NP_777168_1_spondin_1_precursor__Bos_taurus_:0.00269996,((XP_003123014_4_spondin_1__Sus_scrofa_:0.00798383,(((sp_Q9HCB6_SPON1_HUMAN_Spondin_1_OS_Homo_sapiens_OX_9606_GN_SPON1_PE_1_SV_2:0.00269499,((XP_508295_3_spondin_1__Pan_troglodytes_:0.00000001,XP_034788091_1_spondin_1__Pan_paniscus_:0.00000001):0.00000001,(XP_002822053_2_spondin_1__Pongo_abelii_:0.00051056,XP_018893034_2_spondin_1__Gorilla_gorilla_gorilla_:0.0022468):0.001277):0.00000001):0.00883956,(XP_002708869_1_PREDICTED__spondin_1__Oryctolagus_cuniculus_:0.00765414,(((((tr_F1R2Z9_F1R2Z9_DANRE_F_spondin_OS_Danio_rerio_OX_7955_GN_spon1b_PE_4_SV_3:0.22792674,(XP_039254629_1_spondin_1_like__Styela_clava_:1.23488146,((XP_038071797_1_spondin_1_like__Patiria_miniata_:0.67628625,XP_030844169_1_spondin_1__Strongylocentrotus_purpuratus_:0.80840079):0.60375498,(XP_031569176_1_spondin_2_like_isoform_X1__Actinia_tenebrosa_:1.69287884,(NP_495473_2_F_spondin__Caenorhabditis_elegans_:0.87346948,(XP_003251296_1_spondin_1__Apis_mellifera_:0.40655406,NP_477435_1_fat_spondin__Drosophila_melanogaster_:0.45334153):0.74308794):0.47409994):0.23483552):0.15931894):0.6643844):0.0775869,(XP_023809284_1_spondin_1_isoform_X2__Oryzias_latipes_:0.06632448,(XP_030271163_1_spondin_1_isoform_X2__Sparus_aurata_:0.06056328,XP_015808377_1_PREDICTED__spondin_1_isoform_X1__Nothobranchius_furzeri_:0.05760945):0.02029315):0.07810038):0.10821856,(XP_018115643_1_spondin_1__Xenopus_laevis_:0.06026129,XP_040184219_1_LOW_QUALITY_PROTEIN__spondin_1__Rana_temporaria_:0.07493775):0.07257345):0.03845536,((XP_006028011_1_spondin_1__Alligator_sinensis_:0.00000001,XP_014457833_1_PREDICTED__spondin_1__Alligator_mississippiensis_:0.00272047):0.0198566,(XP_005499371_1_spondin_1_isoform_X1__Columba_livia_:0.00894452,(NP_990182_1_spondin_1_precursor__Gallus_gallus_:0.00717678,XP_031409214_1_spondin_1__Meleagris_gallopavo_:0.03435523):0.0073133):0.04255717):0.03155454):0.06222997,(NP_663559_1_spondin_1_precursor__Mus_musculus_:0.0094986,NP_742064_2_spondin_1_precursor__Rattus_norvegicus_:0.00000001):0.01723198):0.00507924):0.00394207):0.00062552,(XP_023095364_1_spondin_1__Felis_catus_:0.00656353,XP_534067_2_spondin_1__Canis_lupus_familiaris_:0.00669731):0.00166144):0.0015286):0.01085373,(XP_017915073_1_PREDICTED__spondin_1__Capra_hircus_:0.001349,XP_027835169_1_spondin_1__Ovis_aries_:0.00000001):0.00270269):0.00000001):0.00270671):0.00135147):0.29777182):0.01560531);
BLAST to find more sequences

Created by Puigbo and Nakamura @ University of Turku (2022)